CN110624060A - Traditional Chinese medicine preparation for treating infantile diarrhea and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating infantile diarrhea and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
Abstract
The invention discloses a traditional Chinese medicine preparation for treating infantile diarrhea, which is characterized by being prepared from the following components in parts by weight: 5-10 parts of schisandra chinensis, 5-10 parts of capsicum frutescens, 3-6 parts of pericarpium citri reticulatae, 2-5 parts of liquorice, 1-3 parts of bamboo leaves, 3-6 parts of white paeony root, 4-8 parts of cistanche, 3-6 parts of plantain herb and 10-15 parts of pig bone. The invention also discloses a preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea. The traditional Chinese medicine preparation for treating infantile diarrhea disclosed by the invention is rich in raw material sources, low in cost, convenient and quick to use, remarkable in treatment effect on infantile diarrhea, free of toxic and side effects, and safe and convenient to use.
Description
Technical Field
The invention belongs to the technical field of drug treatment, particularly relates to a formula of a traditional Chinese medicine preparation for treating infantile diarrhea, and particularly relates to a traditional Chinese medicine preparation with good curative effect on infantile diarrhea and a preparation method thereof.
Background
With the improvement of living standard and the change of life style of people, digestive tract diseases are one of the common clinical diseases, the incidence rate is on the trend of rising year by year, and diarrhea is one of the common symptoms of the diseases. According to the world health organization, infectious diarrhea is the highest infectious disease of infants in developing countries, the fatality rate is about 20 per thousand, and about 460 million infants are lost every year only in the sub, non and Rad regions. Therefore, it is very important to treat infantile diarrhea in real time.
To treat infantile diarrhea in a targeted manner, the cause of infantile diarrhea needs to be known first. The diarrhea of the disease is the usual diarrhea, namely the times of defecation are more than usual, and the nature is changed and more water is contained. The diarrhea is caused by a plurality of reasons, firstly, dysentery and enteritis caused by bacteria, viral enteritis caused by viruses, pathogenic colibacillosis generally occurs in summer, also called summer diarrhea, viral enteritis is often seen in autumn, also called autumn diarrhea, digestive enzyme secretion reduction activity caused by poor digestibility of infants is lower, tolerance of multi-food is poor, diarrhea caused by digestive dysfunction occurs, acidity in stomach of children is lower than that of adults, antibacterial ability is poor, immunoglobulin in blood is lower, intestinal infection is easily caused, stale or deteriorated milk or other food is eaten, and vomiting and diarrhea are caused; or diarrhea due to gastrointestinal digestive function caused by excessive food of infants, which is dyspepsia.
There are many existing methods for treating infantile diarrhea, but the treatment usually requires hospitalization, and has a long course of disease and high cost. The oral anti-inflammatory drug and the injection infusion are adopted for treatment, so that the treatment course is long, the side effect is large, and the influence on infants is large; the traditional Chinese medicine also adopts external drugs for treatment, but the problems of unsatisfactory treatment effect, high cost, slow effect and the like generally exist.
The Chinese patent application with application number 96117162.6 and publication number CN1181249A discloses a Chinese herbal medicine of an infantile diarrhea paste, which adopts precious medicines such as goldthread root, musk and the like, and rosin is required to be added for oil refining in the preparation process, so the medicine has the defects of high cost and complex preparation process.
The patent with the application number of 201210182863.6 discloses a Chinese medicinal orally disintegrating tablet for treating infantile diarrhea, which comprises the following components in part by weight: 10 parts of codonopsis pilosula, 10 parts of bighead atractylodes rhizome, 9 parts of poria cocos, 10 parts of semen coicis, 9 parts of rhizoma atractylodis, 10 parts of Chinese pulsatilla root, 6 parts of ash bark, 6 parts of kudzu root, 3 parts of fructus amomi, 10 parts of semen plantaginis, 10 parts of fried Chinese yam, 10 parts of fried hawthorn, 10 parts of fried medicated leaven, 10 parts of fried malt, 6 parts of myrobalan, 6 parts of honey-fried licorice root, and a proper amount of dextrin, microcrystalline cellulose, lactose, polyvinylpyrrolidone and magnesium stearate; the traditional Chinese medicine oral disintegrating agent is taken without water, automatically disintegrates and dissolves in the oral cavity, can be taken smoothly through normal physiological swallowing action, is mainly used for treating diarrhea caused by dysfunction of gastric transport and transformation due to spleen deficiency, dyspepsia and spleen qi deficiency, and has a plurality of medicinal ingredients and complex components.
Therefore, the finding of the traditional Chinese medicine preparation for treating infantile diarrhea, which has the advantages of obvious curative effect on infantile diarrhea, no toxic or side effect, and safe and convenient medication, has very important significance.
Disclosure of Invention
The invention mainly aims to provide the traditional Chinese medicine preparation for treating the infantile diarrhea, which has the advantages of rich raw material sources, low cost, convenience and quickness in use, obvious treatment effect on the infantile diarrhea, no toxic or side effect, and safety and convenience in medication. Meanwhile, the invention also provides a preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea.
In order to achieve the above purposes, the technical scheme adopted by the invention is as follows: the traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
Further, the traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by weight: 5-10 parts of schisandra chinensis, 5-10 parts of capsicum frutescens, 3-6 parts of pericarpium citri reticulatae, 2-5 parts of liquorice, 1-3 parts of bamboo leaves, 3-6 parts of white paeony root, 4-8 parts of cistanche, 3-6 parts of plantain herb and 10-15 parts of pig bone.
As a preferred embodiment of the invention, the traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by mass: 50g of schisandra chinensis, 50g of capsicum frutescens, 30g of pericarpium citri reticulatae, 20g of liquorice, 10g of bamboo leaves, 30g of white paeony root, 40g of cistanche, 30g of plantain herb and 100g of pig bone.
Further, the preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea.
According to the preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea provided by the embodiment of the invention, the sieving is preferably 100-200-mesh sieve.
According to the method for preparing the traditional Chinese medicine preparation for treating infantile diarrhea of the embodiment of the invention, preferably, the saline is a low-concentration sodium chloride aqueous solution or normal saline.
Preferably, the mass percentage concentration of the sodium chloride aqueous solution is 0.5-0.8 wt%.
Preferably, the preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water, making into paste, and making into round cake.
Preferably, the diameter of the round cake is 1-2cm, and the thickness of the round cake is 0.1-0.4 cm.
Due to the application of the technical scheme, compared with the prior art, the invention has the following advantages:
(1) the preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea provided by the invention is simple and feasible, economic and effective, environment-friendly, low in energy consumption, high in production effect and product qualification rate, and can realize safe, efficient and rapid preparation of the traditional Chinese medicine preparation for treating infantile diarrhea.
(2) The traditional Chinese medicine preparation for treating infantile diarrhea provided by the invention overcomes the defects that the traditional Chinese medicine preparation for treating infantile diarrhea has long treatment course, great side effect and great influence on infants; the traditional Chinese medicine composition has the defects of non-ideal treatment effect, high expense, slow effect taking, excessive medicinal ingredients and complex components, and has the advantages of rich raw material sources, low cost, convenience and quickness in use, remarkable treatment effect on infantile diarrhea, no toxic or side effect, and safety and convenience in medication.
(3) According to the traditional Chinese medicine preparation for treating infantile diarrhea provided by the invention, the added schisandra chinensis is warm in gastric acid, enters the lung channel, heart channel and kidney channel, has the functions of astringing and fixing color, and can be used for treating chronic diarrhea; the spicy rice has the effects of warming middle energizer and relieving pain; chen Guang Pi is bitter in taste and warm in nature, enters lung meridian and spleen meridian, and has the effects of regulating qi and invigorating spleen; the pig bone is warm in nature and has the functions of relieving diarrhea and invigorating stomach; the traditional Chinese medicine composition is reasonably compatible with other medicines and has a synergistic effect, the principle of monarch, minister, assistant and guide is met, and the effect of treating infantile diarrhea can be realized; has the effects of dispelling cold, relieving diarrhea and relieving pain, treats both symptoms and root causes, and has obvious curative effect on infantile diarrhea.
(4) The traditional Chinese medicine preparation for treating infantile diarrhea provided by the invention has the advantages of conditioning and applying simultaneously, warming and invigorating spleen and kidney, clearing heat and drying dampness, cooling blood and removing stagnancy, and supporting spleen and inhibiting liver to cause enteritis, is exact in curative effect, high in cure rate, convenient to operate, suitable for symptoms such as enteritis, chronic colitis, infantile diarrhea, abdominal distension and the like, and is simple to operate and free of pain particularly for infantile diarrhea.
Detailed Description
The following description is presented to disclose the invention so as to enable any person skilled in the art to practice the invention. The preferred embodiments in the following description are given by way of example only, and other obvious variations will occur to those skilled in the art.
Example 1
The traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
The traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by weight: 5 parts of schisandra chinensis, 5 parts of capsicum frutescens, 3 parts of pericarpium citri reticulatae, 2 parts of liquorice, 1 part of bamboo leaves, 3 parts of white paeony root, 4 parts of cistanche, 3 parts of plantain herb and 10 parts of pig bone.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea.
The sieving is to sieve through a 100-mesh sieve.
The brine is a low-concentration sodium chloride aqueous solution; the mass percentage concentration of the sodium chloride aqueous solution is 0.5-0.8 wt%.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water to prepare into paste, and making into round cake shape; the diameter of the round cake is 1cm, and the thickness of the round cake is 0.1 cm.
Example 2
The traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
The traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by weight: 6.5 parts of schisandra chinensis, 6 parts of capsicum frutescens, 4 parts of pericarpium citri reticulatae, 3 parts of liquorice, 1.5 parts of bamboo leaves, 4 parts of radix paeoniae alba, 5 parts of cistanche, 4 parts of plantain herb and 11 parts of pig bone.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea.
The sieving is 120 mesh sieving.
The brine is normal brine.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water to prepare into paste, and making into round cake shape; the diameter of the round cake is 1.2cm, and the thickness of the round cake is 0.2 cm.
Example 3
The traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
The traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by weight: 8 parts of schisandra chinensis, 7.5 parts of capsicum frutescens, 4.5 parts of pericarpium citri reticulatae, 3.5 parts of liquorice, 2 parts of bamboo leaves, 4.5 parts of white paeony roots, 6 parts of cistanche salsa, 4.5 parts of plantain herbs and 13 parts of pig bones.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea.
The sieving is to sieve through a 150-mesh sieve; the saline is low-concentration sodium chloride aqueous solution or normal saline; the mass percentage concentration of the sodium chloride aqueous solution is 0.65 wt%.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water to prepare into paste, and making into round cake shape; the diameter of the round cake is 1.5cm, and the thickness of the round cake is 0.25 cm.
Example 4
The traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
The traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by weight: 9 parts of schisandra chinensis, 9 parts of capsicum frutescens, 5.5 parts of pericarpium citri reticulatae, 4.5 parts of liquorice, 2.5 parts of bamboo leaves, 5.5 parts of white paeony roots, 7.5 parts of cistanche salsa, 5.5 parts of plantain herbs and 14.5 parts of pig bones.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea; the sieving is to sieve through a 180-mesh sieve; the brine is a low-concentration sodium chloride aqueous solution; the mass percentage concentration of the sodium chloride aqueous solution is 0.75 wt%.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water to prepare into paste, and making into round cake shape; the diameter of the round cake is 1.8cm, and the thickness of the round cake is 0.35 cm.
Example 5
The traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
The traditional Chinese medicine preparation for treating infantile diarrhea is prepared from the following components in parts by weight: 10 parts of schisandra chinensis, 10 parts of capsicum frutescens, 6 parts of pericarpium citri reticulatae, 5 parts of liquorice, 3 parts of bamboo leaves, 6 parts of white paeony root, 8 parts of cistanche, 6 parts of plantain herb and 15 parts of pig bone.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea; the sieving is to sieve through a 200-mesh sieve; the brine is a low-concentration sodium chloride aqueous solution; the mass percentage concentration of the sodium chloride aqueous solution is 0.8 wt%.
The preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water to prepare into paste, and making into round cake shape; the diameter of the round cake is 2cm, and the thickness of the round cake is 0.4 cm.
Comparative example 1
The present example provides a Chinese medicinal preparation for treating infantile diarrhea, which has a formula and a preparation method substantially the same as those of example 1, except that schisandra chinensis is not added.
Comparative example 2
The present example provides a Chinese medicinal preparation for treating infantile diarrhea, which has a formula and a preparation method which are basically the same as those of example 1, except that the rice peppers are not added.
Comparative example 3
This example provides a Chinese medicinal preparation for treating infantile diarrhea, which has substantially the same formulation and preparation method as example 1, except that no pericarpium Citri Reticulatae viride is added
Comparative example 4
The present example provides a Chinese medicinal preparation for treating infantile diarrhea, which has a formulation and a preparation method substantially the same as those of example 1, except that no pig bone is added.
Comparative example 5
The traditional Chinese medicine preparation for treating infantile diarrhea is sold in the market.
In order to further illustrate the beneficial technical effects of the traditional Chinese medicine preparation for treating infantile diarrhea in the embodiment of the present invention, the traditional Chinese medicine preparation for treating infantile diarrhea prepared in the above embodiments 1-5 and comparative examples 1-5 is subjected to clinical experiments, the experimental results are shown in table 1, and the experimental methods are as follows: 400 children volunteers with diarrhea are randomly selected and divided into 10 groups, each group corresponds to examples 1-5 and comparative examples 1-5, the traditional Chinese medicine preparation for treating the diarrhea of each example is externally applied to the Shenque point of the sick children, fixed by using an adhesive tape, gently massaged for 10-15 minutes, changed once a day, and used for 3 times as a treatment course. The condition of the sick infants is observed and counted after one treatment course.
The evaluation criteria were:
and (3) healing: patients with infantile diarrhea, emesis, fever, dehydration, abnormal tongue quality, abnormal tongue fur, etc. and no recurrence for one week;
the method has the following advantages: the infant diarrhea of the patient is controlled, the diarrhea frequency is obviously reduced, and the complicating symptoms are relieved;
and (4) invalidation: the diarrhea of the infant of the patient is not improved, and the complicating symptoms are not reduced or even aggravated.
TABLE 1 results of clinical experiments
| Item | Invalidation | Is effective | Recovery method | High efficiency |
| Unit of | Human being | Human being | Human being | ％ |
| Example 1 | 2 | 4 | 34 | 95.0 |
| Example 2 | 1 | 3 | 36 | 97.5 |
| Example 3 | 0 | 1 | 39 | 100.0 |
| Example 4 | 0 | 2 | 38 | 100.0 |
| Example 5 | 0 | 0 | 40 | 100.0 |
| Comparative example 1 | 5 | 5 | 30 | 87.5 |
| Comparative example 2 | 5 | 9 | 26 | 87.5 |
| Comparative example 3 | 7 | 8 | 25 | 82.5 |
| Comparative example 4 | 6 | 9 | 25 | 85.0 |
| Comparative example 6 | 10 | 10 | 20 | 75.0 |
The data result shows that the effective rate of the traditional Chinese medicine preparation for treating infantile diarrhea disclosed by the invention is more than or equal to 95.0%, and the effective rate of the traditional Chinese medicine paste in the comparative example is less than or equal to 87.5%, so that the traditional Chinese medicine preparation for treating infantile diarrhea disclosed by the invention has a better treatment effect and is a result of synergistic effect of all the components.
Claims (9)
1. The traditional Chinese medicine preparation for treating infantile diarrhea is characterized by being prepared from the following components: fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica.
2. The traditional Chinese medicine preparation for treating infantile diarrhea according to claim 1, which is characterized by being prepared from the following components in parts by weight: 5-10 parts of schisandra chinensis, 5-10 parts of capsicum frutescens, 3-6 parts of pericarpium citri reticulatae, 2-5 parts of liquorice, 1-3 parts of bamboo leaves, 3-6 parts of white paeony root, 4-8 parts of cistanche, 3-6 parts of plantain herb and 10-15 parts of pig bone.
3. The traditional Chinese medicine preparation for treating infantile diarrhea according to claim 2, which is characterized by being prepared from the following components in parts by mass: 50g of schisandra chinensis, 50g of capsicum frutescens, 30g of pericarpium citri reticulatae, 20g of liquorice, 10g of bamboo leaves, 30g of white paeony root, 40g of cistanche, 30g of plantain herb and 100g of pig bone.
4. The traditional Chinese medicine preparation for treating infantile diarrhea according to any one of claims 1 to 3, wherein the preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea comprises the following steps: mixing fructus Schisandrae chinensis, fructus Capsici, pericarpium Citri Reticulatae Chachiensis, radix Glycyrrhizae, folium Bambusae, radix Paeoniae alba, herba cistanches, herba plantaginis, and Os Sus domestica at a certain proportion, grinding into fine powder, sieving, adding saline water, and making into paste to obtain the Chinese medicinal preparation for treating infantile diarrhea.
5. The traditional Chinese medicine preparation for treating infantile diarrhea as claimed in claim 4, wherein the sieving is 100-mesh and 200-mesh sieving.
6. The traditional Chinese medicine preparation for treating infantile diarrhea according to claim 4, wherein the saline is a low-concentration sodium chloride aqueous solution or normal saline.
7. The traditional Chinese medicine preparation for treating infantile diarrhea according to claim 6, wherein the mass percentage concentration of the sodium chloride aqueous solution is 0.5-0.8 wt%.
8. The traditional Chinese medicine preparation for treating infantile diarrhea according to claim 4, wherein the preparation method of the traditional Chinese medicine preparation for treating infantile diarrhea further comprises the following steps: adding saline water, making into paste, and making into round cake.
9. The traditional Chinese medicine preparation for treating infantile diarrhea according to claim 8, wherein the diameter of the cake is 1-2cm, and the thickness is 0.1-0.4 cm.
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Application publication date: 20191231 |