CN104069304A - Spray for treating halitosis caused by function imbalance of internal organs and preparation method thereof - Google Patents
Spray for treating halitosis caused by function imbalance of internal organs and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a spray for treating halitosis caused by function imbalance of internal organs. The spray is prepared from the following main raw materials at weight ratio: 9-15 parts of water chestnut, 6-12 parts of sweet clover, 5-10 parts of soapstone, 15-20 parts of honeysuckle, 10-15 parts of membranous milkvetch root, 5-15 parts of liquorice, 4-9 parts of baical skullcap root, 15-25 parts of mentha haplocalyx, 15-30 parts of green tea, 12-20 parts of sugar candy and 10-25 parts of hericium erinaceus. The spray has the function of halitosis removal, can well relieve thick and greasy tongue, bitter mouth and dry throat, weak chest, gastrointestinal discomfort, insomnia and dreaminess and other symptoms, and has a remarkable therapeutic effect on halitosis caused by function imbalance of internal organs.
Description
Technical field
The present invention relates to Chinese medicine field, especially relate to a kind of spray for the treatment of visceral dysfunction halitosis disease and preparation method thereof.
Background technology
Halitosis disease is also referred to as implication or halitosis, be exactly in population, come out make others be sick of, make own awkward unpleasant implication.Conventionally the persistent period surpasses 20, can be defined as halitosis disease.The people of halitosis, the often symptom such as, dry mouth with bitter taste greasy with thick fur, uncomfortable in chest, the gastrointestinal upset of breathing hard, insomnia and dreamful sleep, constipation.Oral cavity is just as a micro factory, the inside approximately 50,000,000 antibacterials that living, and they stay in dark corner and " day and night work ", gnaw and are biting food detritus, produce the corrupt stink of fermentation, and along with breathing comes out.This is also the feel heavier reason of halitosis later of why wakeing up.The reason that causes halitosis is a lot, is generally divided into ectogenicly and endogenic, and medically alleged halitosis is sick, mainly refers to endogenic.Halitosis is first because oral disease causes, as gingivitis, gingival hemorrhage, alveolar pyorrhea, a large amount of calculus or dirty dirts or have food impaction, deeply build hydrogen sulfide and methanthiol that in hole, food residual produces after bacterial decomposition fermentation, make pH value reach 7.2, generation is shouted and is stamped and Ammonia, thereby produces unpleasant stink.Relevant medical thinks, the reason that causes halitosis disease is mainly to take stomach-fire as main, stomach internal organs accumulated heat, and gastrointestinal dysfunction, dyspepsia, gastrointestinal hemorrhage, constipation etc. cause in implication attacks.Can there is halitosis by meridians in visceral dysfunction, the visceral dysfunction halitosis that we often say is sick.
The basic reason of visceral dysfunction halitosis disease is that gastrointestinal function is disorderly, metabolic function imbalance, and immunity of organisms reduces and causes viscera function to lack of proper care.Modern medicine study shows, this class halitosis disease is to cause viscera function imbalance because immunity of organisms reduces, be difficult to balance and the pathogenic microorganism that suppresses to produce foreign odor chemical compound gas, when prolific pathogenic microorganism reaches certain polymerization amount, in human body, absorb the foreign odor chemical compound gas that can produce high concentration while decomposing nutrition, when foreign odor chemical compound gas reaches finite concentration, gas will enter in blood, and intactly by blood, being transported to pulmonary, stomach, direct oral cavity and nasal cavity excrete.Outside this distinguishing mark of visceral dysfunction halitosis disease symptoms performance antihalitosis, also can be according to patient's individual variation, there are respectively following single or multiple Symptoms: thick fur is greasy, xerostomia, bitter taste, breathe hard, the symptom such as uncomfortable in chest, gastrointestinal upset, frequent micturition, constipation, soreness of the waist and knees, limbs fiber crops pain, easily get angry (women easily gets angry menstrual period), the trick heart are easily perspired, often heating of health, fatiguability, agitation, insomnia, lassitude, giddy, hair are withered, tinnitus.Different halitosis also may indicate various disease.The sick expert Jeffery of Australia's dentistry and halitosis Si Peise represents, in the gas that many systemic disease patients breathe out with some special taste.As the implication band rotten apple taste of diabetic, renal failure patient's implication has a fish like smell, and in the oral cavity of patient with liver cirrhosis, has sulfur smoke, and heart disease easily causes the halitosis of slight putrid taste.
Because uncomfortable in chest, the symptom such as have palpitation, breathe hard, feel suffocated may appear in visceral dysfunction halitosis disease, after there are these symptoms, a lot of people just suspect and oneself obtained heart disease, and even some patient accepted cardiopathic treatment, but final effect is all bad.In addition, visceral dysfunction halitosis disease also may cause the unstable of blood pressure, but also there will be headache, dizziness, tinnitus, the temporary rising that also there will be body temperature, blood glucose having, and such patient will be misdiagnosed as hypertension, diabetes sometimes.Visceral dysfunction halitosis disease also can cause the problem of digestive system sometimes, patient there will be the symptom of appetite decline, appetite minimizing, the flatulence of having the hiccups, there will be severe nausea and vomiting, such a patient's major part all can be made gastroscope, but result is all superficial gastritis or duodenal bulbar ulcer.It is not real gastropathy, and by gastropathy, going treatment is not all right certainly, so the effect of receiving is distinct.Do not look down upon this slight defect of halitosis, it can make people's (especially youngster) closely associate with others, thereby produces inferiority complex, and impact is communication normally.At present, halitosis has had influence on daily life gradually, because there is halitosis, others keeps at a distance with him, other just seals nose serious possible own a mouth, more courteous meeting is passed chewing gum to him, and this reaction makes their stress very large, especially in employment situation more urgent today.
In the method for existing Chinese medicine halitosis disease, publication number CN101181360A(application number 200710114725.3) patent discloses a kind of gargle pharmacy for the treatment of halitosis, and the crude drug that forms effective ingredient is: 10 grams of the Radix Aucklandiae, 6 grams of Flos Caryophyllis, 12 grams of Herba Pogostemoniss, 12 grams of the Radixs Angelicae Dahuricae, 30 grams of Radix Puerariaes.This is medicament, though can alleviate rapidly halitosis symptom, cannot effect a radical cure, and is the medicine of curing the symptoms, not the disease, and undesirable to the curative effect of visceral dysfunction halitosis disease.In addition, Flos Caryophylli mainly originates in Australia and the subtropical and tropical zones in America, in China mainly by cultivating, so rareness relatively.Publication number CN 101744282A(application number 201010103431.2) patent discloses a kind of rice lotus-root congee and packaging process thereof for the treatment of halitosis, and the raw material that forms effective ingredient is: 1000 parts, water, rice 50-150 part, Rhizoma Nelumbinis 50-150 part.This is nutraceutical, can only to halitosis disease, alleviate to some extent to a certain extent, and DeGrain, more cannot effect a radical cure halitosis disease.
Summary of the invention
For the sick present situation lacking of existing treatment visceral dysfunction halitosis, one of object of the present invention is to provide a kind of spray for the treatment of visceral dysfunction halitosis disease, there is feature easy to operate, evident in efficacy, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.Another object is just to provide the preparation method of above-mentioned spray.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of spray for the treatment of visceral dysfunction halitosis disease, taking off the primary raw material of stating weight proportion is prepared from: Corm Eleocharitis 9-15 part, melilotus 6-12 part, Talcum 5-10 part, Flos Lonicerae 15-20 part, Radix Astragali 10-15 part, Radix Glycyrrhizae 5-15 part, Radix Scutellariae 4-9 part, Herba Menthae 15-25 part, green tea 15-30 part, crystal sugar 12-20 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 10-25 part.
Treat a spray for visceral dysfunction halitosis disease, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Corm Eleocharitis 10-14 part, melilotus 7-11 part, Talcum 6-9 part, Flos Lonicerae 16-19 part, Radix Astragali 11-14 part, Radix Glycyrrhizae 7-13 part, Radix Scutellariae 5-8 part, Herba Menthae 17-23 part, green tea 20-25 part, crystal sugar 14-18 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 15-20 part.
Treat a spray for visceral dysfunction halitosis disease, the scheme being more preferably is, takes off the primary raw material of stating weight proportion and is prepared from: 12 parts of Corm Eleocharitiss, 9 parts of melilotuss, 7 parts, Talcum, 18 parts of Flos Loniceraes, 12 parts of the Radixs Astragali, 10 parts, Radix Glycyrrhizae, 6 parts of Radix Scutellariaes, 20 parts of Herba Menthaes, 22 parts of green tea, 16 parts, crystal sugar, 17 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
The preparation method of above-mentioned spray, step is as follows:
(1), by Talcum pulverization, cross 80-120 mesh sieve;
(2) green tea is put in glass container, pours the hot water of 60 ℃-80 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water be crystal sugar consumption 1-5 doubly, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, cease fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 20 ℃-40 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 20-40 minute at a simmer, adds step (1) gained Pulvis Talci after truce, and standing 1-3 hour, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
The preparation method of above-mentioned spray, preferred scheme is: step (1) is crossed 90-110 mesh sieve (preferably 100 mesh sieves).
The preparation method of above-mentioned spray, preferred scheme is: step (2) is poured the hot water (the preferably hot water of 70 ℃) of 65 ℃-75 ℃ into.
The preparation method of above-mentioned spray, preferred scheme is: the consumption of step (3) water is 2-4 times (preferably 3 times) of crystal sugar consumption.
The preparation method of above-mentioned spray, preferred scheme is: step (4) is with the rice wine moistening of 25 ℃-35 ℃ stand-by (preferably 30 ℃).
The preparation method of above-mentioned spray, preferred scheme is: step (5) turns 25-35 at a simmer minute (preferably 30 minutes).
The preparation method of above-mentioned spray, preferred scheme is: step (5) standing 1.5-2.5 hour (preferably 2 hours).
using method: for making the present invention reach optimum therapeuticing effect, during use, in oral cavity, spraying medicine, according to abiding by of doctor, advise and select spray medicine 3-8 time the concrete condition every day of oneself, spray under 2-3 at every turn, 7 days is a course for the treatment of.
This spray is remarkable to the sick effect of visceral dysfunction halitosis, not only has the effect of eliminating halitosis, and this spray also has depressed liver-energy dispersing and QI regulating to a certain extent simultaneously, adjust intestinal nourishing the stomach, yin nourishing removing heat from blood, heat-clearing and toxic substances removing, the effect of nourishing YIN to lower pathogenic fire, removes toxin and the metabolism putrefaction in human body, assembled.
The pharmacological effect of each crude drug is respectively:
Corm Eleocharitis: belong to shallow water perennial root draft, do vegetable with bulb edible.Corm Eleocharitis color of the leather purple is black, and meat is pure white, and the sweet succulence of taste is clear and melodious good to eat, has the good reputation of " underground pear " from ancient times, and what northerner looked is " south of the River Radix Ginseng ".Corm Eleocharitis is nutritious, contains protein, fat, crude fibre, carotene, vitamin B, vitamin C, ferrum, calcium, phosphorus and carbohydrate, can eat something rare, and also can be used for the cooking, can starch processed, also can make Chinese medicine.Chinese medicine and pharmacy think Corm Eleocharitis have quench the thirst, help digestion, antipyretic function.Sweet in the mouth, cold in nature.Return stomach warp.Have clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, promotes the production of body fluid and moisturizes, diuresis relieving constipation, and the de-swelling that helps digestion, conditioning hemorrhoid or dysentery are had blood in stool, woman uterine bleeding, discomfort in the throat, mass in the abdomen is gathered, the effect that conjunctival congestion is hidden from view.For lung-dryness syndrome due to deficiency of YIN, cough ant phlegm, jaundice, dysentery, poliomyelitis, constipation.In addition, Corm Eleocharitis contains a kind of antimicrobial component, and to the certain effect that reduced blood pressure, this material also has preventive and therapeutic effect to cancer.
Melilotus: bitter in the mouth, light, cool in nature, nontoxic.Belong to pulse family, biennial herb, high 40-100 centimetre.Originate in northeast, south China, southwestern various places, all the other each province are usually by cultivation.Be born in hillside, riverbank, roadside, chiltern meadow.The effect with heat-clearing and toxic substances removing, is used for the treatment of skin scar, red wind, dysentery with red and white feces, gonorrhea.
Talcum: sweet in the mouth, light, cold in nature.Return bladder, lung, stomach warp.There is inducing diuresis for treating stranguria syndrome, clearing away summer-heat, the effect of damp eliminating sore.For pyretic stranguria, stranguria caused by urinary stone, urinates hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea, eczema, eczema, miliaria.
Flos Lonicerae: sweet in the mouth, cold in nature.Return lung, the heart, stomach warp.There is heat-clearing and toxic substances removing, the effect of wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating.
The Radix Astragali: sweet in the mouth, warm in nature.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis toxin expelling, the effect of evacuation of pus.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, diabetes.
Radix Glycyrrhizae: sweet in the mouth, property is flat.GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, limbs pain, carbuncle sore tumefacting virus.
Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect.For vomiting uncomfortable in chest, dysentery, jaundice, cough due to lung-heat, carbuncle sore tumefacting virus, frequent fetal movement.
Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel.There is wind-dispelling heat-dissipating, refresh oneself, throat, rash, the effect of resolving depression.Be used for having a headache dizzy, conjunctival congestion and swelling pain, pharyngalgia celostomia, toothache, measles without adequate eruption, urticaria pruritus, hypochondriac pain due to stagnation of liverQI gastral cavity is swollen.
Green tea: be the tea of making without fermentation, therefore more reservation the natural materials of fresh leaf, the tea polyphenols containing, catechin, chlorophyll, caffeine, aminoacid, vitamins and other nutritious components are also more.These natural nutrition compositions in green tea, have special-effect to anti-aging, anti-cancer, anticancer, sterilization, antiinflammatory etc., be other teas can't be obtained.In China, green tea is described as " state's drink ".Modern science studies confirm that in a large number, and Folium Camelliae sinensis contains and the closely-related biochemical of health really.Acrid in the mouth, cold in nature.Return liver, spleen, lung, kidney channel.Having refreshes oneself clears away heart-fire, clearing away summer-heat, eliminate indigestion and phlegm, go greasy fat-reducing, the effect of the relieving restlessness that clears away heart-fire, removing toxic substances relieving alcoholic intoxication, promoting the production of body fluid to quench thirst, pathogenic fire reducing improving eyesight, dysentery relieving dehumidifying.For modern disease, Radiation sickness, cardiovascular and cerebrovascular disease, cancer, acute and chronic dysentery, amebic dysentery.
Crystal sugar: be the crystallization reproduced goods of Saccharum Sinensis Roxb., the crystal sugar adularescent of Nature creating, micro-Huang, light grey isochrome, add all kinds of colored crystal sugar of food coloring in addition in addition on market, such as green, blue, orange, micro-multiple color such as red, dark red.Because its crystallization is as ice shape, therefore named crystal sugar, crystal sugar quality is pure, not perishable, except can do confection edible, also can be used for gourmet food sweeting agent, dipping drinks and nourishing adjuvant drug etc. prepare medicines.Sweet in the mouth, property is flat, nontoxic.Return lung, spleen channel.Have YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough, supplements blood glucose, the effect of diuresis removing toxic substances.For xeropulmonary cough, dry cough without phlegm, cough with blood-flecked phlegm, the deficiency of the lung, the cough with asthma due to wind and cold fatigue, infantile malaria, fasting dysentery, aphtha, acute toothache.
Hericium erinaceus (Bull. Ex Fr.) Pers.: property is flat, sweet in the mouth.Return spleen, stomach warp.For Aphyllophorales hedgehog fungus section, the culture of process submerged fermentation is through separation and Extraction gained, and main component is polysaccharide, aminoacid etc., is the raw material of the preparations such as FUFANG WEINING PIAN, is widely used in field of medicaments.Have antiulcer and antiinflammatory, antitumor, hepatoprotective, increase immunity, defying age, raising body's hypoxia tolerance, increase heart blood output, accelerates the effect of body blood circulation, reduction blood glucose and blood fat.For weakness of the spleen and stomach, dyspepsia, neurasthenia, gastric duodenal ulcer, superficial gastritis, chronic gastritis, the esophageal carcinoma, gastric cancer, intestinal cancer, sexual impotence, digestive tract tumor.
The principle of spray of the present invention based on traditional Chinese medical herbal treatment visceral dysfunction halitosis disease, the medical material of selecting is more common, cheap and easy to operate.Disorderly for gastrointestinal function, immunity of organisms reduces and causes visceral dysfunction, to regulate the function of recovering imbalance, carry out balance and suppress to produce the pathogenic microorganism of foreign odor chemical compound gas, thereby making the concentration of this foreign odor chemical compound gas keep rational concentration.The recovery function of take is primary treatment direction, and visceral dysfunction halitosis is had to fabulous therapeutical effect.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1treat a spray for visceral dysfunction halitosis disease, take off and state primary raw material and be prepared from (getting 10g for every part): 9 parts of Corm Eleocharitiss, 6 parts of melilotuss, 5 parts, Talcum, 15 parts of Flos Loniceraes, 10 parts of the Radixs Astragali, 5 parts, Radix Glycyrrhizae, 4 parts of Radix Scutellariaes, 15 parts of Herba Menthaes, 15 parts of green tea, 12 parts, crystal sugar, 10 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
A kind of spray preparation process for the treatment of visceral dysfunction halitosis disease is as follows:
(1), by Talcum pulverization, cross 80 mesh sieves;
(2) green tea is put in glass container, pours the hot water of 60 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water is 1 times of crystal sugar consumption, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, ceases fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 20 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 20 minutes at a simmer, adds step (1) gained Pulvis Talci after truce, standing 1 hour, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
Using method: spraying medicine in oral cavity, select spray medicine 3-8 time every day, spray under 2-3 at every turn, 7 days is a course for the treatment of.
model case onecao XX, man, 8 years old, people from Cao County, Heze city of Shandong province.Summer in 2010, be diagnosed as visceral dysfunction halitosis sick, greasy with thick fur, dry mouth with bitter taste, the trick heart is easily perspired, easily irritated symptom.Father and mother have been a lot of hospitals with him and have received treatment, but halitosis be never controlled effectively, and find that child's emotional status also gradually becomes more irritated and do not like so much and spoken.Mother's introduction according to boy: at primary school he is a wise and active boy originally, can be after suffering from halitosis, and whole people becomes and felt oneself inferior.
Heard afterwards that the present invention treated the spray of visceral dysfunction halitosis disease, so also like to try and see, used the spray of embodiment 1 gained treatment visceral dysfunction halitosis disease, sprayed every day 3 times, used after 3 days, obviously felt that halitosis had alleviated; Use after 1 course for the treatment of, the sensation trick heart has not so easily been perspired yet, and so easily not irritated yet, gradually takes to other child and plays; After 2 courses for the treatment of of treatment, halitosis thoroughly has been cured, he has exposed again that smile that how long it is since we last met on the face, has given the child's simplicity that part lose for change happy! And his mother has been unable to bear falling down happy tear.Drug withdrawal so far without recurrence, during have no adverse reaction.
embodiment 2treat a spray for visceral dysfunction halitosis disease, take off and state primary raw material and be prepared from (getting 30g for every part): 15 parts of Corm Eleocharitiss, 12 parts of melilotuss, 10 parts, Talcum, 20 parts of Flos Loniceraes, 15 parts of the Radixs Astragali, 15 parts, Radix Glycyrrhizae, 9 parts of Radix Scutellariaes, 25 parts of Herba Menthaes, 30 parts of green tea, 20 parts, crystal sugar, 25 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
A kind of spray preparation process for the treatment of visceral dysfunction halitosis disease is as follows:
(1), by Talcum pulverization, cross 120 mesh sieves;
(2) green tea is put in glass container, pours the hot water of 80 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water is 5 times of crystal sugar consumption, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, ceases fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 40 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 40 minutes at a simmer, adds step (1) gained Pulvis Talci after truce, standing 3 hours, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
Using method: spraying medicine in oral cavity, select spray medicine 3-8 time every day, spray under 2-3 at every turn, 7 days is a course for the treatment of.
model case twozhao XX, man, 52 years old, people from Qihe County, Dezhou City Shandong Province.Suffering from seriousness halitosis, is all full not only sticky but also smelly saliva in the mouth when get up every morning.Because the reason of halitosis, be in love or in ensuing work, all suffered from very large puzzlement at an early age, in the work that baffles in emotion, have some setbacks, make Mr. Zhao very irritated.But also often with dryness in the nasal cavity, dry cough, vexed uneasiness regularly, insomnia and dreamful sleep, lassitude loin and legs, dry mouth and throat, especially night are more serious, often because xerostomia or daydream are waken up.Repeatedly go to outpatient service and hospital, also used folk prescription among the people, but the effect substantially all not had, or be temporary improvement and recurrence afterwards.
Afterwards, once recognizing that with the exchanging of friend the present invention treats the spray of visceral dysfunction halitosis disease, so use the spray of embodiment 2 gained treatment visceral dysfunction halitosis diseases, spray every day 8 times, use after 1 course for the treatment of, halitosis symptom obviously improves, and also seldom can wake up night; Use about similar 2 courses for the treatment of, tongue fur originally thick on tongue is also thin a lot, and saliva is substantially also less smelly; When medication is in the time of similar 1 month, completely not smelly in oral cavity, once disliked that his grandson also started to approach him gradually, one family is enjoying family happiness, and Mr. Zhao feels incomparable happiness now! Drug withdrawal so far without recurrence, during have no adverse reaction.
embodiment 3treat a spray for visceral dysfunction halitosis disease, take off and state primary raw material and be prepared from (getting 50g for every part): 10 parts of Corm Eleocharitiss, 7 parts of melilotuss, 6 parts, Talcum, 16 parts of Flos Loniceraes, 11 parts of the Radixs Astragali, 7 parts, Radix Glycyrrhizae, 5 parts of Radix Scutellariaes, 17 parts of Herba Menthaes, 20 parts of green tea, 14 parts, crystal sugar, 15 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
A kind of spray preparation process for the treatment of visceral dysfunction halitosis disease is as follows:
(1), by Talcum pulverization, cross 90 mesh sieves;
(2) green tea is put in glass container, pours the hot water of 65 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water is 2 times of crystal sugar consumption, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, ceases fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 25 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 25 minutes at a simmer, adds step (1) gained Pulvis Talci after truce, standing 1.5 hours, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
Using method: spraying medicine in oral cavity, select spray medicine 3-8 time every day, spray under 2-3 at every turn, 7 days is a course for the treatment of.
embodiment 4treat a spray for visceral dysfunction halitosis disease, take off and state primary raw material and be prepared from (getting 20g for every part): 14 parts of Corm Eleocharitiss, 11 parts of melilotuss, 9 parts, Talcum, 19 parts of Flos Loniceraes, 14 parts of the Radixs Astragali, 13 parts, Radix Glycyrrhizae, 8 parts of Radix Scutellariaes, 23 parts of Herba Menthaes, 25 parts of green tea, 18 parts, crystal sugar, 20 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
A kind of spray preparation process for the treatment of visceral dysfunction halitosis disease is as follows:
(1), by Talcum pulverization, cross 110 mesh sieves;
(2) green tea is put in glass container, pours the hot water of 75 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water is 4 times of crystal sugar consumption, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, ceases fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 35 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 35 minutes at a simmer, adds step (1) gained Pulvis Talci after truce, standing 2.5 hours, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
Using method: spraying medicine in oral cavity, select spray medicine 3-8 time every day, spray under 2-3 at every turn, 7 days is a course for the treatment of.
model case threeking XX, female, 28 years old.Rizhao City, Shandong Province from Donggang District.Frequent xerostomia, bitter taste, especially serious when getting up morning with empty stomach, and also tongue surface whiting after getting up morning, inappetence, light when heavy during halitosis symptom, while weighing, oneself can smell one niff.And outside antihalitosis, often cold with thirsty drink, aphtha of the mouth and tongue, gingival swelling and pain, abdominal distention, the symptom such as suppurate hemorrhage.Folk prescription has also tried much, but bad while always being fashion.The halitosis of suffering from for oneself, it is very awkward that Mrs Wang feels always, many times she has to select to escape the occasion of some friends' parties etc., does not contact for a long time and also allows her lose some good friends simultaneously.Before going out sometimes, brush teeth, can not cross and within several hours, will feel the taste coming out in own oral cavity.
Use the aerosol spray agent of embodiment 4 gained treatment visceral dysfunction halitosis diseases, spray 6-10 every day, uses after 3 days, and halitosis symptom obviously improves, and has felt salubrious in the mouth a lot; Use after 1 course for the treatment of, found thick thin fur on tongue many, saliva is substantially less smelly, and the symptoms such as xerostomia, bitter taste, gingival swelling and pain, aphtha of the mouth and tongue have also disappeared substantially.When adhering to using 2 courses for the treatment of, completely not smelly in mouthful always.So far without recurrence, there is not bad phenomenon in drug withdrawal yet.
embodiment 5treat a spray for visceral dysfunction halitosis disease, take off and state primary raw material and be prepared from (getting 10g for every part): 12 parts of Corm Eleocharitiss, 9 parts of melilotuss, 7 parts, Talcum, 18 parts of Flos Loniceraes, 12 parts of the Radixs Astragali, 10 parts, Radix Glycyrrhizae, 6 parts of Radix Scutellariaes, 20 parts of Herba Menthaes, 22 parts of green tea, 16 parts, crystal sugar, 17 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
A kind of spray preparation process for the treatment of visceral dysfunction halitosis disease is as follows:
(1), by Talcum pulverization, cross 100 mesh sieves;
(2) green tea is put in glass container, pours the hot water of 70 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water is 3 times of crystal sugar consumption, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, ceases fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 30 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 30 minutes at a simmer, adds step (1) gained Pulvis Talci after truce, standing 2 hours, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
Using method: spraying medicine in oral cavity, select spray medicine 3-8 time every day, spray under 2-3 at every turn, 7 days is a course for the treatment of.
test example: the clinical practice of the spray of embodiment 5 gained treatments visceral dysfunction halitosis diseases: in August, 2010-2012 year February, in 3 hospitals, screen 100 routine patients, women's 50 examples wherein, male's 50 examples, maximum 76 years old age, minimal ages 6 years old (is got rid of the Index for examinations such as the heart, liver, kidney, blood not the patient of normal range, trimester of pregnancy, women breast-feeding their children, the patient who has ethanol, drug dependence medical history, participated in other drug clinical trial person's patient in 3 months and other are not suitable for crowd).Test 1 month before, carries out Continuous Observation to this crowd, records symptom and variation.Be divided at random two groups, experimental group (M-F equates, is respectively 25 examples) and matched group (M-F equates, is respectively 25 examples).Experimental group is taken embodiment 5 products obtained therefroms, and using method is: adhering to mouth spray pharmacy 5 times every day, 7 days is a course for the treatment of.Matched group is taken other medicine (XIANGSHA YANGWEI WAN), using method: each 8 balls, every day 3 times.Curative effect situation criterion: cure: halitosis symptom disappears completely.Effective: halitosis symptom alleviates or part disappears.Invalid: halitosis symptom unchanged or recurrence.Wherein always effectively comprise and curing with effective, result is as shown in the table:
Table 1
therapeutic effect: take healing 38 examples of the spray of embodiment 5 gained treatments visceral dysfunction halitosis diseases, cure rate is up to 76%, effective 11 examples, and effective percentage 22%, invalid 1 example, total effective rate has reached 98%.And take healing 15 examples of other products XIANGSHA YANGWEI WAN, and cure rate has only reached 30%, effective 20 examples, and invalid 15 examples, inefficiency has reached 30%, total effective rate 70%.Can find out: the successful of taking the spray of embodiment 5 gained treatments visceral dysfunction halitosis diseases is better than taking other products.
Remarks: have 19 male 19 female in the 38 routine patients that cure in experimental group, have 7 male 8 female in the 15 routine patients that cure in matched group.Can infer that thus this spray has equal curative effect to men and women.
Table 2
From table 2, can obviously find out: take ratio that each symptom of experimental group of the spray of embodiment 5 gained treatments visceral dysfunction halitosis diseases is eased apparently higher than the matched group of taking other medicine XIANGSHA YANGWEI WAN, and after 3 courses for the treatment of, each remission rate of experimental group has all reached more than 92%, can conclude that this spray has good curative effect to visceral dysfunction halitosis disease.
Spray of the present invention has made up the vacancy for the treatment of in the traditional Chinese medical science in visceral dysfunction halitosis disease, and visceral dysfunction halitosis disease is had to significant curative effect, and to compare side effect little with medicine of other treatment halitosis disease.Each crude drug that the present invention treats the spray of visceral dysfunction halitosis disease mixes, when first mouthful of spray, just can alleviate rapidly the symptom of halitosis, increase the confidence of patient's cure diseases, and mouthful spray pharmacy is easy to use, and batching is all to choose more common medical material, cheap, ordinary people can life-time service, has not only reduced the burden on health and has also reduced pecuniary burden.Take 1 course for the treatment of, more than 54% feeling takes a turn for the better to some extent, and malaise symptoms improves; Take 2 courses for the treatment of, more than 78% feeling takes a turn for the better to some extent, and malaise symptoms improves or disappears, halitosis, and thick fur, the symptoms such as dryness in the nasal cavity xerostomia are largely improved; Take 3 courses for the treatment of, more than 94% feeling takes a turn for the better to some extent, and malaise symptoms disappears substantially, halitosis, thick fur, distending pain, the weak transference cure that waits, most of patient's self-induction recovery from illness.In experimental group, take 3 more than the course for the treatment of, effective percentage can reach 94%, and matched group is only 64%.
Finally it should be noted that, embodiment is the specific embodiment of optimum of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. a spray for the treatment of visceral dysfunction halitosis disease, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Corm Eleocharitis 9-15 part, melilotus 6-12 part, Talcum 5-10 part, Flos Lonicerae 15-20 part, Radix Astragali 10-15 part, Radix Glycyrrhizae 5-15 part, Radix Scutellariae 4-9 part, Herba Menthae 15-25 part, green tea 15-30 part, crystal sugar 12-20 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 10-25 part.
2. spray according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Corm Eleocharitis 10-14 part, melilotus 7-11 part, Talcum 6-9 part, Flos Lonicerae 16-19 part, Radix Astragali 11-14 part, Radix Glycyrrhizae 7-13 part, Radix Scutellariae 5-8 part, Herba Menthae 17-23 part, green tea 20-25 part, crystal sugar 14-18 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 15-20 part.
3. spray according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 12 parts of Corm Eleocharitiss, 9 parts of melilotuss, 7 parts, Talcum, 18 parts of Flos Loniceraes, 12 parts of the Radixs Astragali, 10 parts, Radix Glycyrrhizae, 6 parts of Radix Scutellariaes, 20 parts of Herba Menthaes, 22 parts of green tea, 16 parts, crystal sugar, 17 parts of Hericium erinaceus (Bull. Ex Fr.) Pers.es.
4. according to the preparation method of the arbitrary described spray of claim 1-3, it is characterized in that, step is as follows:
(1), by Talcum pulverization, cross 80-120 mesh sieve;
(2) green tea is put in glass container, pours the hot water of 60 ℃-80 ℃ into, soak 30 minutes, filter filtrate for later use;
(3) crystal sugar is placed in to pot, adds water and boil, the consumption of water be crystal sugar consumption 1-5 doubly, can hear crystal sugar sound of crack in Pi in water, after crystal sugar melts completely, cease fire;
(4) by Corm Eleocharitis, melilotus, Flos Lonicerae, the Radix Astragali, Radix Glycyrrhizae, Radix Scutellariae and Herba Menthae mix homogeneously, stand-by with the rice wine moistening of 20 ℃-40 ℃;
(5) step (4) gained mixture and Hericium erinaceus (Bull. Ex Fr.) Pers. are joined in step (2) gained filtrate, intense fire is fried open, and turns 20-40 minute at a simmer, adds step (1) gained Pulvis Talci after truce, and standing 1-3 hour, gets supernatant stand-by;
(6) step (3) gained crystal sugar water is mixed homogeneously with step (5) gained supernatant, be aided with pharmaceutically acceptable carrier package and get final product.
5. preparation method according to claim 4, is characterized in that: step (1) is crossed 90-110 mesh sieve (preferably 100 mesh sieves).
6. preparation method according to claim 4, is characterized in that: step (2) is poured the hot water (the preferably hot water of 70 ℃) of 65 ℃-75 ℃ into.
7. preparation method according to claim 4, is characterized in that: the consumption of step (3) water is 2-4 times (preferably 3 times) of crystal sugar consumption.
8. preparation method according to claim 4, is characterized in that: step (4) is with the rice wine moistening of 25 ℃-35 ℃ stand-by (preferably 30 ℃).
9. preparation method according to claim 4, is characterized in that: step (5) turns 25-35 at a simmer minute (preferably 30 minutes).
10. preparation method according to claim 4, is characterized in that: step (5) standing 1.5-2.5 hour (preferably 2 hours).
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104491296A (en) * | 2014-10-09 | 2015-04-08 | 黄珊 | Traditional Chinese medicine preparation for eliminating functional dyspepsia-caused ozostomia and preparation method thereof |
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| Title |
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| 孙红艳: "口臭中医证治相应关系的研究", 《世界中西医结合杂志》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104491296A (en) * | 2014-10-09 | 2015-04-08 | 黄珊 | Traditional Chinese medicine preparation for eliminating functional dyspepsia-caused ozostomia and preparation method thereof |
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Address after: 014000, Yingbin District, 2 National Road, Qingshan District, Inner Mongolia, Baotou Applicant after: Chen Hongyan Address before: 250014, building 2, modern leisurely City, No. 34 Jiefang East Road, Lixia District, Ji'nan, Shandong Applicant before: Chen Hongyan |
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