CN106620397A - Granules capable of preventing and treating dental ulcer and preparation method of granules - Google Patents
Granules capable of preventing and treating dental ulcer and preparation method of granules Download PDFInfo
- Publication number
- CN106620397A CN106620397A CN201710116478.4A CN201710116478A CN106620397A CN 106620397 A CN106620397 A CN 106620397A CN 201710116478 A CN201710116478 A CN 201710116478A CN 106620397 A CN106620397 A CN 106620397A
- Authority
- CN
- China
- Prior art keywords
- parts
- particle
- weight
- dental ulcer
- treating dental
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 231100000397 ulcer Toxicity 0.000 title claims abstract description 47
- 208000025865 Ulcer Diseases 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 239000008187 granular material Substances 0.000 title abstract 8
- 239000002994 raw material Substances 0.000 claims abstract description 48
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 33
- 244000197580 Poria cocos Species 0.000 claims abstract description 31
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 31
- 239000000706 filtrate Substances 0.000 claims abstract description 31
- 244000268590 Euryale ferox Species 0.000 claims abstract description 30
- 235000006487 Euryale ferox Nutrition 0.000 claims abstract description 29
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 52
- 239000002245 particle Substances 0.000 claims description 50
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 42
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 31
- 241000209205 Coix Species 0.000 claims description 26
- 235000007354 Coix lacryma jobi Nutrition 0.000 claims description 26
- 229910052742 iron Inorganic materials 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 16
- 239000000047 product Substances 0.000 claims description 14
- 244000241838 Lycium barbarum Species 0.000 claims description 12
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 12
- 235000005489 dwarf bean Nutrition 0.000 claims description 11
- 238000005469 granulation Methods 0.000 claims description 10
- 230000003179 granulation Effects 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 28
- 210000000952 spleen Anatomy 0.000 abstract description 20
- 210000002784 stomach Anatomy 0.000 abstract description 8
- 238000002156 mixing Methods 0.000 abstract description 7
- 230000036541 health Effects 0.000 abstract description 6
- 244000241872 Lycium chinense Species 0.000 abstract description 3
- 235000015468 Lycium chinense Nutrition 0.000 abstract description 3
- 210000000582 semen Anatomy 0.000 abstract description 3
- 244000077995 Coix lacryma jobi Species 0.000 abstract description 2
- 244000269722 Thea sinensis Species 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 240000005717 Dioscorea alata Species 0.000 abstract 1
- 241000620028 Dolichoris Species 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000000227 grinding Methods 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- 235000008935 nutritious Nutrition 0.000 abstract 1
- 208000020670 canker sore Diseases 0.000 description 27
- 239000003814 drug Substances 0.000 description 18
- 210000000214 mouth Anatomy 0.000 description 13
- 201000010099 disease Diseases 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
- 230000036407 pain Effects 0.000 description 12
- 235000013305 food Nutrition 0.000 description 10
- 210000003734 kidney Anatomy 0.000 description 10
- 210000004072 lung Anatomy 0.000 description 9
- 235000009508 confectionery Nutrition 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 210000002105 tongue Anatomy 0.000 description 8
- 206010012735 Diarrhoea Diseases 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 6
- 238000009835 boiling Methods 0.000 description 6
- 230000007812 deficiency Effects 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 208000004880 Polyuria Diseases 0.000 description 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 4
- 208000002399 aphthous stomatitis Diseases 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000027939 micturition Effects 0.000 description 4
- 210000004400 mucous membrane Anatomy 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- 235000019640 taste Nutrition 0.000 description 4
- 230000008673 vomiting Effects 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 3
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 240000001417 Vigna umbellata Species 0.000 description 3
- 235000011453 Vigna umbellata Nutrition 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000037213 diet Effects 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- -1 galactolipin Chemical compound 0.000 description 3
- 230000000116 mitigating effect Effects 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 230000000306 recurrent effect Effects 0.000 description 3
- 229960002477 riboflavin Drugs 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 150000003722 vitamin derivatives Chemical class 0.000 description 3
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 2
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 2
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 229930003471 Vitamin B2 Natural products 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- SRBFZHDQGSBBOR-LECHCGJUSA-N alpha-D-xylose Chemical compound O[C@@H]1CO[C@H](O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-LECHCGJUSA-N 0.000 description 2
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 2
- 229960003022 amoxicillin Drugs 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 208000019902 chronic diarrheal disease Diseases 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000002218 hypoglycaemic effect Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 201000005630 leukorrhea Diseases 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 210000003097 mucus Anatomy 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 2
- 210000003800 pharynx Anatomy 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 230000000171 quenching effect Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 230000007958 sleep Effects 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 2
- 229960003495 thiamine Drugs 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 210000005182 tip of the tongue Anatomy 0.000 description 2
- 206010046901 vaginal discharge Diseases 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 235000019164 vitamin B2 Nutrition 0.000 description 2
- 239000011716 vitamin B2 Substances 0.000 description 2
- 229960003487 xylose Drugs 0.000 description 2
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- HOMSOWZTBJWNHP-UHFFFAOYSA-N 5-chlorothiadiazole Chemical compound ClC1=CN=NS1 HOMSOWZTBJWNHP-UHFFFAOYSA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- 206010061623 Adverse drug reaction Diseases 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 206010004542 Bezoar Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 102000030523 Catechol oxidase Human genes 0.000 description 1
- 108010031396 Catechol oxidase Proteins 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 244000247747 Coptis groenlandica Species 0.000 description 1
- 235000002991 Coptis groenlandica Nutrition 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- 101100276976 Drosophila melanogaster Drak gene Proteins 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 241001149422 Ganoderma applanatum Species 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- 206010028034 Mouth ulceration Diseases 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 208000007117 Oral Ulcer Diseases 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 235000007189 Oryza longistaminata Nutrition 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 208000010513 Stupor Diseases 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 102000002262 Thromboplastin Human genes 0.000 description 1
- 108010000499 Thromboplastin Proteins 0.000 description 1
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 1
- 241000219977 Vigna Species 0.000 description 1
- 235000010716 Vigna mungo Nutrition 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000002605 anti-dotal effect Effects 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 235000013527 bean curd Nutrition 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000005178 buccal mucosa Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 235000019504 cigarettes Nutrition 0.000 description 1
- LOHQECMUTAPWAC-UHFFFAOYSA-N coagulin Natural products C1C(C)=C(CO)C(=O)OC1C1(C)C(C2(C)CCC3C4(C(=O)CC=CC4=CCC43)C)(O)CCC24O1 LOHQECMUTAPWAC-UHFFFAOYSA-N 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003866 digestant Substances 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 230000002497 edematous effect Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000027119 gastric acid secretion Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- JMANVNJQNLATNU-UHFFFAOYSA-N glycolonitrile Natural products N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 229960003284 iron Drugs 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- VDYCLYGKCGVBHN-UHFFFAOYSA-N pachymaic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC(=C)C(C)C)C(O)=O)C(O)CC21C VDYCLYGKCGVBHN-UHFFFAOYSA-N 0.000 description 1
- SRDNLMOBFKJOSD-UHFFFAOYSA-N pachymic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C(O)=O)C(O)CC21C SRDNLMOBFKJOSD-UHFFFAOYSA-N 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 206010036596 premature ejaculation Diseases 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000021251 pulses Nutrition 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 1
- 229940032091 stigmasterol Drugs 0.000 description 1
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 1
- 235000016831 stigmasterol Nutrition 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 201000000498 stomach carcinoma Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses granules capable of preventing and treating dental ulcer and a preparation method of the granules, belonging to the field of health food. The granules are prepared from the following raw materials in parts by weight: 15-25 parts of common yam rhizome, 5-15 parts of coix seeds, 5-15 parts of gorgon fruits, 5-15 parts of semen phaseoli, 5-10 parts of poria cocos, 1-2 parts of Tie Guanyin tea leaves, 1-2 parts of Chinese wolfberry fruits, and 1-2 parts of semen dolichoris. The preparation method of the granules comprises the following steps: (1) grinding the raw materials; (2) carrying out decocting and carrying out filtering; (3) mixing the filtrates; (4) carrying out concentrating; and (5) carrying out pelleting. The preparation method is simple, the use is convenient, the raw materials are easily available, the cost is low, and the popularization and use are easy; the curative effects are good, no toxic and side effects exist, and the granules are suitable for all people suffering from dental ulcer. The granules provided by the invention can prevent and treat dental ulcer, can tonify the spleen and nourish the stomach, can build the body, are nutritious and healthy, and can be used for daily health care.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of particle of anti-treating dental ulcer and preparation method thereof.
Background technology
Canker sore is a kind of common disease, the parts such as mucous membrane of mouth, tongue, throat is mainly in, with oral mucosal disease
It is characterized.Recurrent oral ulceration, aphtha are modal canker sore, and the incidence of disease in crowd is about 20%.Mouthful
Chamber ulcer can betide any age, and it is higher that women suffers from this sick ratio, can occur throughout the year, and in spring, people are more susceptible to suffer from
This disease, is characterized in recurrent exerbation, cusalgia unbearably, patient's normal diet is affected, while multiple complications can also be caused.
Modal canker sore is exactly that oral mucosa is damaged, and causes canker sore, festers, and the lighter affects normal digestion
Function, severe one even causes the major diseases such as canceration.The cause of disease and mechanism of causing a disease of canker sore is still indefinite.Inducement can
Can be local trauma, stress, food, medicine, hormonal readiness change and vitamin or microelement deficiencies.Canker sore is easy
Recurrence, cycle is short, and easily infect, such as to treat not in time, Relapse rate outbreak delays lasting, can also switch to " Behcet synthesis
Disease ", or even involve internal organs, cause great pain to the work and life of patient.
At present, the method for treating oral ulcer generally adopts Western medicine anti-inflammatory, though Western medicine has preferable bacteriostasis simultaneously
Good clinical short-term curative effects, but Western medicine large side effects, easily generation drug resistance and dependence are achieved, there is recurrence rate
High and adverse drug reaction, severe patient possibly even causes flora imbalance, mucous membrane of mouth to strip off and superposition sense, and long-term taking can shadow
Ring the health status of patient.
In prior art, treating the Chinese medicine of canker sore has two kinds of local application and medicine for oral administration, and local application is good for such as golden larynx
Spray, Bingpeng San, superior sore throat powder etc., though these medicines can temporary relief of symptoms, also cause the bitter picotement in oral cavity, do not relax
Clothes, and can not effect a radical cure.And medicine for oral administration is all often antipyretic and antidotal type, specific aim is not strong, also has strong stimulation to alimentary canal, easily draws
Diarrhoea is played, the people for suffering from indiestion, especially pregnant woman, child cannot take.In addition, the conventional topical remedy of canker sore controls
Treat, formulation mostly is powder, pulvis, GARG, spraying, film etc., and classification has medicine, apparatus, disappear font size product and daily chemical products
Deng, also various folk prescriptions among the people, but not a kind of particularly effective product can obtain the consistent accreditation of patient.
The content of the invention
The purpose of the present invention is for the deficiencies in the prior art, there is provided a kind of good effect, it is in good taste, using safety, cost
Cheap particle of anti-treating dental ulcer and preparation method thereof.
To reach above-mentioned purpose, the technical scheme that the present invention takes is as follows：
A kind of particle of anti-treating dental ulcer, it is characterised in that be made up of the raw material of following parts by weight：15 ~ 25 parts of Huaihe River mountain, the heart of a lotus seed
5 ~ 15 parts of rice, 5 ~ 15 parts of Gorgon fruit, 5 ~ 15 parts of rde bean, 5 ~ 10 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin.
Above-mentioned technical proposal, preferably, being made up of the raw material of following parts by weight：18 ~ 21 parts of Huaihe River mountain, the seed of Job's tears 8 ~ 10
Part, 8 ~ 12 parts of Gorgon fruit, 8 ~ 10 parts of rde bean, 4 ~ 5 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin.
Above-mentioned technical proposal, preferably, being made up of the raw material of following parts by weight：20 parts of Huaihe River mountain, 10 parts of the seed of Job's tears, Gorgon fruit
10 parts, 10 parts of rde bean, 5 parts of Poria cocos, 1 part of Iron Guanyin.
Above-mentioned technical proposal, preferably, being made up of the raw material of following parts by weight：15 ~ 25 parts of Huaihe River mountain, the seed of Job's tears 5 ~ 15
Part, 5 ~ 15 parts of Gorgon fruit, 5 ~ 15 parts of rde bean, 5 ~ 10 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin, 1 ~ 3 part of matrimony vine, 1 ~ 3 part of French beans.
Above-mentioned technical proposal, preferably, being made up of the raw material of following parts by weight：15 ~ 17 parts of Huaihe River mountain, 6 ~ 9 parts of the seed of Job's tears,
9 ~ 12 parts of Gorgon fruit, 10 ~ 12 parts of rde bean, 8 ~ 10 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin, 1 ~ 2 part of matrimony vine, 1 ~ 2 part of French beans.
Above-mentioned technical proposal, preferably, being made up of the raw material of following parts by weight：17 parts of Huaihe River mountain, 8 parts of the seed of Job's tears, Gorgon fruit
10 parts, 11 parts of rde bean, 8 parts of Poria cocos, 1 part of Iron Guanyin, 1.5 parts of matrimony vine, 1.5 parts of French beans.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material is crushed by weight, is well mixed, obtain raw mixture；
（2）By step（1）The raw mixture for obtaining is by weight 1 with clear water：5 ~ 10 are decocted, and are filtered after decoction, weight
It is multiple 3 times, decoct 60-90 minutes every time；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is for 1.10 ~ 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract of gained is spray-dried, granulation, obtains product particle.
Above-mentioned technical proposal, preferably, the step（2）In, raw mixture is 1 with the weight ratio of clear water：7.
Above-mentioned technical proposal, preferably, the step（2）In, decocting time is slow fire 80-90 minutes or intense fire 60-
70 minutes.
Above-mentioned technical proposal, preferably, the step（2）In, decoction method is used instead after first decocting 30 minutes with high heat
It is cooked by slow fire 60 minutes.
Above-mentioned technical proposal, preferably, the step（1）In, the powder being ground into is 5 ~ 10 mesh.
Huai Shan, winds herbaceous species, and the mankind eat from ancient times, are one of earliest plants of human consumption.Huaihe River mountain is sweet, property
It is flat, enter lung, spleen, kidney channel；It is not dry oiliness；With strengthening the spleen and tonifying the lung, beneficial stomach kidney tonifying, reinforce the kidney beneficial essence, hearing-improing and eyesight improving, help the five internal organs, strong muscle
Bone, long will to calm the nerves, the effect promoted longevity；Cure mainly weakness of the spleen and the stomach, lassitude, poor appetite, chronic diarrhea and dysentery, Lung Qi deficiency it is dry,
Asthma due to excessive phlegm cough, kidney qi loss, soreness and weakness of waist and knees, lower limb impotence is weak, frequent micturition of quenching one's thirst, premature ejaculation of passing out semen, under band gonorrhoea, skin are red swollen, fat
Etc. illness.Huai Shan contains the materials such as amylase, polyphenol oxidase, is conducive to taste digestion and absorption function, is flat tonifying spleen and stomach simply
Medicine-food two-purpose product, with invigorating spleen and reinforcing stomach, digestant effect.No matter spleen sun is lost or stomach-Yin deficiency, all edible.It is clinically normal
With controlling the illnesss such as weakness of the spleen and the stomach, deficiency of food body is tired, have loose bowels.Huai Shan contains various nutrients, there is strong body, the work of nourishing kidney and replenishing pneuma
With.The diseases such as the effect of Huai Shan has nourishing kidney and replenishing pneuma, generally deficiency of the kidney seminal emission, women leukorrhea is more, frequent urination, can all take it.Huai Shan
Containing saponin, lymphatic temperament, there is a lubrication, moist effect, with benefit lung and restrain cough thus the effect of, can beneficial lung qi, support lung yin, treat lung
Empty phlegm is coughed the disease of chronic cough.Huai Shan contains mucus protein, there is the hypoglycemic effect of drop, can be used to treat diabetes, is diabetes patient
Diet good food.Huai Shan contains substantial amounts of mucus albumen, electrolytes and minerals, can effectively prevent blood fat in the heavy of vascular wall
Form sediment, prevent cardiovascular diseases, obtain effect that beneficial will is calmed the nerves, promoted longevity.It was found that Huai Shan has sedation, anti-liver can be carried out
Stupor.
The seed of Job's tears, is called coix seed, the seed of jog's tears, maize, is the benevolence of grass Job's tears.Its is cool in nature, sweet, light, enters
Spleen, lung, kidney channel, have functions that Li Shui, invigorating the spleen, except numbness, clearing away heat and eliminating pus.Meter Ren be used as medicine have invigorating the spleen, diuresis, heat-clearing, antibechic it
Effect.Because the nutritive value of the seed of Job's tears is very high, it is described as " king of world grass "；In Europe, it is referred to as " life and health
Standing grain "；In Japan, again anti-cancer food is listed in recently, therefore is had a sudden rise in social status.The characteristics of seed of Job's tears has easy digested absorption,
No matter for nourishing or for medical treatment, effect all relaxes very much.
Gorgon fruit, belongs to the astringent medicinal in Chinese medicine, is the dry mature kernal of nymphaeaceae plant Gorgon euryale, originates in Hubei, Hunan, river
The ground such as west, Anhui, also known as current Huang, chicken head fruit, Soviet Union's Huang etc..Gorgon fruit nature and flavor are sweet, puckery, flat.Gorgon fruit contains abundant starch, also contains
Protein, fat, carbohydrate, crude fibre, calcium, phosphorus, iron, thiamine, riboflavin, Yan acid, vitamin and micro carrotene
Deng.The function of Gorgon fruit be tonifying middle-Jiao and Qi, supplementing the kidney to control the nocturnal, eliminating dampness and arresting leucorrhea.It is usually used in emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, in vain
It is turbid, under band.Gorgon fruit can strengthen Small Intestinal, improve urine wood sugar excretion rate, increase serum concentration of carotene, can make lung cancer,
The morbidity risk rate of cancer of the stomach declines, and greatly reduces cancer odds.Simultaneously Gorgon fruit has very high food therapy value, in China certainly
It is ancient as vigor of remaining youthful forever, prevent prematurely senile good thing.
Rde bean, another name：Red bean, red rice bean, rice bean, albumen beans, Chi Shandou, are pulse family, Vigna annual herb.It is red
Red bean is mainly used in Chinese medicine, possess promoting circulation of blood enrich blood, invigorating spleen to remove dampness, removing toxic substances apocenosis the effects such as.Rde bean is mild-natured, sweet, acid, energy
It is inducing diuresis and reducing edema（Oedema, tinea pedis, jaundice, rush down dysentery is had blood in stool, carbuncle swells）, heat-clearing removing jaundice.Rde bean has diuresis, to heart disease
It is beneficial with ephrosis, edematous patient.Rde bean is rich in folic acid, and puerpera, wet nurse eats rde bean lactagogue.Rde bean has
It is good to relax bowel, lowering blood pressure and blood fat, adjust blood sugar, prevention calculus, the effect of body building and weight reducing.Rde bean is in treatment liver
Hardening ascites aspect also has effect.
Poria cocos, also known as beautiful spirit, Fu spirits, Wan Linggui, Fu Tu, the dry sclerotia of Shi Ni shelf funguses section fungi Poria cocos, Chang Jisheng
On pine roots.Poria cocos contains pachymaran, glucose, protein, amino acid, organic acid, fat, lecithin, adenine, courage
Alkali, ergosterol, various enzymes and sylvite etc..The traditional Chinese medical science thinks that Poria cocos slightly sweet flavor is put down, enter the heart, lung, the spleen channel.With eliminating dampness and diuresis,
Dampness removing and do not hinder healthy tendency；Energy strengthening the spleen and stomach, there is antitoxic heart-soothing and sedative.Poria cocos can control difficult urination, and oedema turgor, phlegm and retained fluid is coughed
It is inverse, to vomit inverse, vomiting during early pregnancy is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful to wait disease.Contained pachymic acid has strengthen immunity, resists in Poria cocos
Tumour and the effect of calmness, hypoglycemic etc..Poria cocos can relax gastrointestinal smooth muscle, and gastric acid secretion inhibiting prevents liver cell bad
Extremely, the effects such as antibacterial.Poria cocos can as important dietotherapy kind, Jing often to eat with can invigorating spleen to remove dampness, it is aid digestion, strengthen physique.
Iron Guanyin, belongs to green, is one of Chinese well-known tea.The refined rhythm of delicate fragrance, has natural orchid fragrant after brewing, grow
Taste is pure dense, and fragrant aroma persistently, has " reputation that seven bubbles have lingering fragrance ".In addition to the health care with general tealeaves, also with anti-ageing
Always, anti arteriosclerosis, prevent and treat diabetes, defatting beauty, prevent and treat carious tooth, heat-clearing and fire-reducing, enemy's cigarette is the effects such as sober up.
Matrimony vine, also known as GANQIZI, the sweet state fruit of Chinese wolfberry.The property sweet taste of matrimony vine, the traditional Chinese medical science thinks that it being capable of nourishing liver and kidney, benefit
Shrewd head and blood-nourishing, the immunity for strengthening people.The fruit of Chinese wolfberry is rich in LBP-X, and LBP-X is a kind of water-soluble polysaccharide, by
Arabinose, glucose, galactolipin, mannose, wood sugar, rhamnose this 6 kinds of monosaccharide components composition, with physiologically active, can
Strengthen non-specific immune function, improve resistance against diseases, while matrimony vine can also be antifatigue and reduces blood pressure.
French beans, sweet, slightly warm in nature is vitamin B1, B2 and nicotinic acid, general containing protein, fat, carbohydrate, phosphorus, calcium, iron, zinc
The compositions such as acid, stigmasterol, phosphatide, cyanogen glucoside, blood cell coagulin.French beans can be used for nvigorating the spleen and in, dampness elimination of relieving summer heat, and control summer-heat and damp vomiting and diarrhoea,
Insufficiency of the spleen to vomit inverse, deficiency of food is let out long, and water stops quenching one's thirst, leukorrhea with reddish discharge, infantile malnutrition etc..
Beneficial effect：Among the raw material of the present invention, Huai Shan, the seed of Job's tears, Iron Guanyin are respectively provided with clearing heat and detoxicating effect, and respectively
Effect of raw material is very gentle, using rear non-stimulated, by this several raw materials mixing after, the effect becomes apparent from, for canker sore
Therapeutic effect it is more notable, other raw materials are added in above raw material, then can not only treat canker sore, and can invigorating the spleen be good for
Stomach, supplements the nutrients, and builds up health, it is to avoid the recurrence of canker sore.The present invention has the advantage that relative to prior art：1、
The preparation method of the present invention is simple, easy to use, and abundant raw material source is with low cost, is adapted to promote the use of；2nd, it is of the invention by original
Material is fabricated to particle, and the utilization rate of active components for treating canker sore is high, can effectively alleviate canker sore, and in good taste, energy
Mitigate psychological burden of the patient to general flavour of a drug, while can whet the appetite, patient easily receives；3rd, good effect of the invention,
Can antibacterial, anti-inflammatory, pain relieving, and can repairing ulcer quickly, active ingredient absorbs fast, and has no toxic side effect, and security is good, to oral cavity
Mucous membrane is non-stimulated, is adapted to all groups with canker sore and eats, and the statistics of Jing application examples, the present invention is controlled canker sore
More rate is up to 99%；4th, particle of the invention can preventing canker sore again can be to the oral cavity that produced
Ulcer is treated, and energy physical fitness, and nutrient health can be used as daily food and drink.
Specific embodiment
With reference to specific application examples, the invention will be further described.
Embodiment 1
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：200 grams of Huaihe River mountain, 100 grams of the seed of Job's tears, Gorgon fruit
100 grams, 100 grams of rde bean, 50 grams of Poria cocos, 10 grams of Iron Guanyin.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material Huai Shan, the seed of Job's tears, Gorgon fruit, rde bean, Poria cocos, Iron Guanyin are crushed by weight, crosses 5 mesh sieves；
（2）It is 1 that whole raw materials is pressed raw material total amount with the weight ratio of clear water：5 are decocted, and are filtered after decoction, are repeated 3 times,
Every time intense fire is decocted 60 minutes；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.10 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 1
Mr. Zhou, 55 years old, there is ulcer at not of uniform size 4, diameter 15-25mm in oral cavity, surface is covered with white pseudomembrane, surrounding
Micro- red, substantially, thermostimulation to the cold increases canker sores.Voluntarily pain has been alleviated after oral amoxicillin, but recurrent exerbation, pain
Unbearably, diet is difficult, irritated insomnia for pain.Patient is taken after mixing it with water with particle obtained in embodiment 1, boiling water, 5 grams every time, sooner or later each daily
Once, ulcer surface pain substantially mitigates after 1 day, and symptom disappears after 3 days, recovery from illness.
Embodiment 2
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：210 grams of Huaihe River mountain, 80 grams of the seed of Job's tears, Gorgon fruit
110 grams, 90 grams of rde bean, 50 grams of Poria cocos, 20 grams of Iron Guanyin.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material Huai Shan, the seed of Job's tears, Gorgon fruit, rde bean, Poria cocos, Iron Guanyin are crushed by weight, crosses 10 mesh sieves；
（2）It is 1 that whole raw materials is pressed raw material total amount with the weight ratio of clear water：7 are decocted, and are filtered after decoction, are repeated 3 times,
Every time intense fire is decocted 70 minutes；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 2
Mrs Yang, 40 years old, there is a canker sore medical history for many years, when it is light when weight, once repeatedly took Chinese and Western medicine, fail to obtain expection and control
Therapeutic effect, monthly still there is outbreak 3-5 time, after increase because of canker sore, hurt like hell and diagnosis and treatment of coming.Burst at the upper lip one of patient
Ulcer, lower lip has ulcer at three, and sublingual ulcer such as soya bean is big, and ulcer center is concave, and surrounding blush, surface is covered with faint yellow vacation
Film, scorching hot pain, feverish sensation over the palm, abdominal distension, dry and hard excrement, bitter taste mouth is greasy, red tongue body, yellow and greasy fur.Patient is with obtained in embodiment 2
Particle, boiling water is taken after mixing it with water, 8 grams every time, and sooner or later respectively once daily, canker sores sense after 1 day somewhat mitigates, and pain is obvious after 2 days
Mitigate, symptom disappears after 4 days, recovery from illness.After recovery from illness, holding takes weekly 1 time, observes 5 months, without recurrence.
Embodiment 3
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：180 grams of Huaihe River mountain, 90 grams of the seed of Job's tears, Gorgon fruit 90
Gram, 100 grams of rde bean, 40 grams of Poria cocos, 10 grams of Iron Guanyin.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material Huai Shan, the seed of Job's tears, Gorgon fruit, rde bean, Poria cocos, Iron Guanyin are crushed by weight, crosses 5 mesh sieves；
（2）It is 1 that whole raw materials is pressed raw material total amount with the weight ratio of clear water：10 are decocted, and are filtered after decoction, are repeated 3 times,
90 minutes are cooked by slow fire every time；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 3
Miss Wu, 35 years old, the wheat harvesting period of canker sore one, (8 pieces/times, one day three of early stage large dose oral administration vitamin B compound
It is secondary), somewhat take a turn for the better after 3 days, later large dose oral administration vitamin B compound effect on driving birds is not good, add vitamin C, Amoxicillin, afterwards instead
Recurrence is made, and repeated in the same position of left cheek film and swells and ache, and has abscess.To examine, abscess portion punctures out fester, fester Jing bacteriums
Culture, as a result to corrode Aitken bacterium, is diagnosed as the left cheek film abscess in bacterial oral cavity.Patient with particle obtained in embodiment 3,
Boiling water is taken after mixing it with water, 4 grams every time, and sooner or later each daily once canker sores sense after 2 days somewhat mitigates, and pain substantially mitigates after 3 days, and 5
Symptom disappears after it, recovery from illness, observes 3 months, without recurrence.
Embodiment 4
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：250 grams of Huaihe River mountain, 150 grams of the seed of Job's tears, Gorgon fruit
150 grams, 150 grams of rde bean, 70 grams of Poria cocos, 15 grams of Iron Guanyin.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material Huai Shan, the seed of Job's tears, Gorgon fruit, rde bean, Poria cocos, Iron Guanyin are crushed by weight, crosses 10 mesh sieves；
（2）It is 1 that whole raw materials is pressed raw material total amount with the weight ratio of clear water：9 are decocted, and are filtered after decoction, are repeated 3 times,
80 minutes are cooked by slow fire every time；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.10 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 4
Lu, schoolgirl, 12 years old, oral cavity pain can not take food, and occur chestnut grain sample small red dot or exanthema vesiculosum in the tip of the tongue or lip, burn
Hot pain, very then halitosis swelling and aching of gum, the yellow constipation of urine, red tongue with yellowish fur is big as mucous membrane of mouth or the visible several pieces of soya beans of the tip of the tongue, lingual surface
Little ulcer surface, oral secretion plate coating checking candida albicans is positive.Patient is taken after mixing it with water with the particle obtained by embodiment 4, boiling water, often
Secondary 10 grams, sooner or later respectively once daily, fully recover after 2 days.
Embodiment 5
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：180 grams of Huaihe River mountain, 80 grams of the seed of Job's tears, Gorgon fruit 80
Gram, 80 grams of rde bean, 50 grams of Poria cocos, 10 grams of Iron Guanyin.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material Huai Shan, the seed of Job's tears, Gorgon fruit, rde bean, Poria cocos, Iron Guanyin are crushed by weight, crosses 7 mesh sieves；
（2）It is 1 that whole raw materials is pressed raw material total amount with the weight ratio of clear water：6 are decocted, and are filtered after decoction, are repeated 3 times,
Use instead after first decocting 30 minutes with high heat every time and be cooked by slow fire 60 minutes；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 5
Mr. Pei, 30 years old, canker sore outbreak 5 months repeatedly, in department of stomatology, Hospital treatment, used piece bayesian gargle and a cow-bezoar
Shangqing pill, antibiotic, vitamin etc. have no little effect, after open Chinese medicine（Medicine name is unknown）, do not feel any better after clothes, do oral secretion training
Support as fungus growth.Jing friend introductions come here and go to a doctor.Face is sallow dim stagnant when medical, in oral cavity bilateral buccal mucosa, lower lip
Many aphtha points are seen in side and pharynx palate etc., and sore face is light red, lingual surface thin and whitish fur, and bean curd slag specimen tongue at number is seen thereon, and tongue side is with teeth
Print, diet is few, scanty drak urine, defecates less.Patient is taken after mixing it with water with particle obtained in embodiment 5, boiling water, 8 grams every time, sooner or later daily
Respectively once, symptom mitigation after 1 day, symptom disappears after 3 days, recovery from illness, observes 4 months, without recurrence.
Embodiment 6
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：17 parts of Huaihe River mountain, 8 parts of the seed of Job's tears, Gorgon fruit 10
Part, 11 parts of rde bean, 8 parts of Poria cocos, 1 part of Iron Guanyin, 1.5 parts of matrimony vine, 1.5 parts of French beans.
（1）Raw material is crushed by weight, crosses 7 mesh sieves, be well mixed, obtain raw mixture；
（2）By weight it is 1 by raw mixture and clear water：7 are decocted, and are filtered after decoction, are repeated 3 times, and are cooked by slow fire every time
Boil 85 minutes；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 6
Mr. Zhao, 50 years old, there is a canker sore medical history for many years, when it is light when weight, once repeatedly took Chinese and Western medicine, fail to obtain expection
Therapeutic effect, immediate cause canker sore increases and diagnosis and treatment of coming.During examining, ulcer at upper lip two, lower lip has ulcer at three, tongue
Lower ulcer such as soya bean is big, and ulcer center is concave, surrounding blush, and surface is covered with faint yellow pseudomembrane, scorching hot pain, feverish sensation over the palm,
Abdominal distension, dry and hard excrement, bitter taste mouth is greasy, red tongue body, yellow and greasy fur, veins is sliding.Patient is taken after mixing it with water with particle obtained in embodiment 6, boiling water, often
Secondary 5 grams, sooner or later respectively once daily, fully recover after 3 days.
Embodiment 7
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：17 parts of Huaihe River mountain, 9 parts of the seed of Job's tears, Gorgon fruit 10
Part, 10 parts of rde bean, 8 parts of Poria cocos, 1 part of Iron Guanyin, 1 part of matrimony vine, 1 part of French beans.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material is crushed by weight, is well mixed, obtain raw mixture；
（2）By weight it is 1 by raw mixture and clear water：6 are decocted, and are filtered after decoction, are repeated 3 times, and are cooked by slow fire every time
Boil 85 minutes；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.20 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 7
Ms Zhang, 30 years old, started easily long canker sore before 5 years, nearly January carrys out canker sore and increases, and takes vitamin C, A Mo
XiLin, does not feel any better, and Amoxicillin is changed to into ROX, while oral cavity patch ' meaning can be pasted ' effect is still bad.Patient implements
Particle obtained in example 7, boiling water is taken after mixing it with water, 8 grams every time, sooner or later respectively once daily, symptom mitigation after 2 days, symptom disappears after 7 days, fullys recover from an illness
More, observe 5 months, without recurrence.
Embodiment 8
A kind of particle of anti-treating dental ulcer, is made up of the raw material of following parts by weight：A kind of particle of anti-treating dental ulcer, by
The raw material composition of following parts by weight：Above-mentioned technical proposal, preferably, being made up of the raw material of following parts by weight：Huaihe River mountain 16
Part, 8 parts of the seed of Job's tears, 9 parts of Gorgon fruit, 10 parts of rde bean, 9 parts of Poria cocos, 1.5 parts of Iron Guanyin, 1.5 parts of matrimony vine, 1 part of French beans.
The preparation method of the particle of above-mentioned anti-treating dental ulcer, comprises the steps：
（1）Raw material is crushed by weight, is well mixed, obtain raw mixture；
（2）By weight it is 1 by raw mixture and clear water：8 are decocted, and are filtered after decoction, are repeated 3 times, and are first useed force every time
Fire is used instead after decocting 30 minutes and is cooked by slow fire 60 minutes；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract for obtaining is spray-dried, granulation, obtains product particle.
Application examples 8
, 43 years old, there is canker sore 2 years repeatedly in Mr. Li, repeated ulcer in oral cavity, when as when stop, ache at ulcer when sending out
Pain is uncomfortable, affects feed, sleep, once takes the medicines such as vitamin B2, Yiqing Capsule, coptis bolus for clearing the upper heat, and localized pulverization xilei san
Or watermelon crystal spray, can respite pain, promote ulcer surface healing, but can not effect a radical cure, easily recur in fatigue.Because of tired cause
Canker sore recurrence is medical, and pain is uncomfortable, affects feed and sleeps, and feels spiritlessness and weakness, tastelessness, and food is received average, and two just adjust.
Patient's lustreless complexion, there is ulcer at 4 in oral cavity, sore pale complexion, periphery is in pale red, and tongue nature is light, there is indentation on side, tongue is thin white, arteries and veins
Carefully.Card category temper virtual loss, flaring up of deficient fire is controlled and preferably replenished qi to invigorate the spleen, and sweet temperature dissipates fire.Patient is rushed with particle obtained in embodiment 8, boiling water
Clothes, 7 grams every time, sooner or later respectively once daily, and symptom mitigation after 1 day, symptom disappears after 7 days, recovery from illness, half a year is observed, without recurrence.
Except above-mentioned application exception, the present invention has also made the application of the canker sore sufferer of other 100, wherein man 42
Example, female 58,10～68 years old age, average age 32 years old., using the obtained particle of the present invention, 2 times a day, the morning and evening each one for patient
It is secondary.Healing time is 1 ~ 5 day, and cure rate is up to 99%.The present invention is more preferable than the therapeutic effect of common Chinese and Western medicine, and without recurrence
Situation.The particle mouthfeel of the present invention is good, and formula meets canker sore pathogenesis, and nontoxic to human body, patient is easier to connect
Receive, can whet the appetite.Except treat canker sore in addition to, this particle in daily life using not only can preventing canker sore,
Can be used with strengthening body.
Claims (10)
1. a kind of particle of anti-treating dental ulcer, it is characterised in that be made up of the raw material of following parts by weight：15 ~ 25 parts of Huaihe River mountain,
5 ~ 15 parts of the seed of Job's tears, 5 ~ 15 parts of Gorgon fruit, 5 ~ 15 parts of rde bean, 5 ~ 10 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin.
2. the particle of anti-treating dental ulcer as claimed in claim 1, it is characterised in that by the raw material group of following parts by weight
Into：18 ~ 21 parts of Huaihe River mountain, 8 ~ 10 parts of the seed of Job's tears, 8 ~ 12 parts of Gorgon fruit, 8 ~ 10 parts of rde bean, 4 ~ 5 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin.
3. the particle of anti-treating dental ulcer as claimed in claim 2, it is characterised in that by the raw material group of following parts by weight
Into：20 parts of Huaihe River mountain, 10 parts of the seed of Job's tears, 10 parts of Gorgon fruit, 10 parts of rde bean, 5 parts of Poria cocos, 1 part of Iron Guanyin.
4. the particle of anti-treating dental ulcer as claimed in claim 1, it is characterised in that also including the original of following weight fraction
Material：1 ~ 3 part of matrimony vine, 1 ~ 3 part of French beans.
5. the particle of anti-treating dental ulcer as claimed in claim 4, it is characterised in that by the raw material group of following parts by weight
Into：15 ~ 17 parts of Huaihe River mountain, 6 ~ 9 parts of the seed of Job's tears, 9 ~ 12 parts of Gorgon fruit, 10 ~ 12 parts of rde bean, 8 ~ 10 parts of Poria cocos, 1 ~ 2 part of Iron Guanyin, matrimony vine
1 ~ 2 part, 1 ~ 2 part of French beans.
6. the particle of anti-treating dental ulcer as claimed in claim 5, it is characterised in that by the raw material group of following parts by weight
Into：17 parts of Huaihe River mountain, 8 parts of the seed of Job's tears, 10 parts of Gorgon fruit, 11 parts of rde bean, 8 parts of Poria cocos, 1 part of Iron Guanyin, 1.5 parts of matrimony vine, French beans 1.5
Part.
7. the preparation method of the particle of the anti-treating dental ulcer described in any one of claim 1 to 6, it is characterised in that include as
Lower step：
（1）Raw material is crushed by weight, is well mixed, obtain raw mixture；
（2）By step（1）The raw mixture for obtaining is by weight 1 with clear water：5 ~ 10 are decocted, and are filtered after decoction, weight
It is multiple 3 times, decoct 60-90 minutes every time；
（3）By step（2）3 filtrates for obtaining merge and are well mixed, and obtain comprehensive filtrate；
（4）The medicinal extract that relative density is for 1.10 ~ 1.15 is determined when comprehensive filtrate is concentrated into into 70 DEG C；
（5）By step（4）The medicinal extract of gained is spray-dried, granulation, obtains product particle.
8. the preparation method of the particle of anti-treating dental ulcer as claimed in claim 7, it is characterised in that：The step（2）In,
Raw mixture is 1 with the weight ratio of clear water：7.
9. the preparation method of the particle of anti-treating dental ulcer as claimed in claim 7, it is characterised in that：The step（2）In,
Decocting time is slow fire 80-90 minutes or intense fire 60-70 minutes.
10. the preparation method of the particle of anti-treating dental ulcer as claimed in claim 7, it is characterised in that：The step（2）
In, decoction method is used instead after first decocting 30 minutes with high heat and is cooked by slow fire 60 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710116478.4A CN106620397A (en) | 2017-03-01 | 2017-03-01 | Granules capable of preventing and treating dental ulcer and preparation method of granules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710116478.4A CN106620397A (en) | 2017-03-01 | 2017-03-01 | Granules capable of preventing and treating dental ulcer and preparation method of granules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106620397A true CN106620397A (en) | 2017-05-10 |
Family
ID=58846447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710116478.4A Pending CN106620397A (en) | 2017-03-01 | 2017-03-01 | Granules capable of preventing and treating dental ulcer and preparation method of granules |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106620397A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107501435A (en) * | 2017-09-30 | 2017-12-22 | 南京正宽医药科技有限公司 | The extracting method of pachymaran and its application |
-
2017
- 2017-03-01 CN CN201710116478.4A patent/CN106620397A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 健康大讲堂编委会: "《药膳健康吃法东问西答》", 31 December 2012, 湖南美术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107501435A (en) * | 2017-09-30 | 2017-12-22 | 南京正宽医药科技有限公司 | The extracting method of pachymaran and its application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101695376B (en) | Health-care food for preventing diabetes | |
| CN103416625B (en) | Barley piglet feed and preparation method thereof | |
| CN101797326B (en) | Chinese materia medica preparation for treating borborygmus diarrhoea and preparation method thereof | |
| KR20110073717A (en) | A functional food and making method of thereof | |
| CN102934759A (en) | Milk cow forage for improving milk quality | |
| CN104381691A (en) | Functional feed for preventing nutritional anemia of piglets and preparation method of functional feed | |
| CN106562428A (en) | Facial beautification and body shaping soft extract and preparation method thereof | |
| KR20130063074A (en) | Blood glucose and blood pressure decrease action composition | |
| CN106579395A (en) | Kidney-tonifying and hair-restoring nutrition powder and preparation method thereof | |
| KR20070013114A (en) | Composition for tea | |
| CN107596197A (en) | A kind of strongly fragrant tea of tonifying Qi solution and preparation method thereof | |
| CN104273439A (en) | Noodle capable of tonifying spleen and promoting appetite and preparation method thereof | |
| CN103431260A (en) | Mixed-grain full-nutrition formulation food for patients with gastrointestinal tract malabsorption and pancreatitis | |
| CN107343935A (en) | A kind of pulvis for infant spleen-tonifying and preparation method thereof | |
| CN106620397A (en) | Granules capable of preventing and treating dental ulcer and preparation method of granules | |
| CN102526537A (en) | Medicinal composition for treating hyperglycemia | |
| KR20110025454A (en) | Functional food and method of preparing thereof | |
| KR100815333B1 (en) | Healthfood using medicalherbs and method preparing thereof | |
| CN106729163A (en) | A kind of Chinese medicine composition for preventing and treating damp-heat constitution and preparation method thereof | |
| CN106361982A (en) | Edible and medicinal traditional Chinese medicine preparations for treating diabetes and preparing method thereof | |
| KR100497845B1 (en) | food having herbal medicine for assisting healthy and producing method thereof | |
| CN105832868A (en) | Soaking method of pepper and cantharides selenium-rich medicinal liquor | |
| CN105851398A (en) | Dendrobium officinale health tea and preparation method thereof | |
| CN104940735A (en) | Dendrobium officinale traditional Chinese medicinal composition capable of strengthening spleen and stomach and preparation method thereof | |
| CN104740487B (en) | A kind of Chinese medicine composition for treating children anorexia and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20190923 Address after: 230036 Hefei Changjiang Road, Anhui, No. 130 Applicant after: Anhui Agricultural University Address before: 516021 Guangdong city of Huizhou province Hui Sha di 2 Road Longhu Bay Applicant before: Li Gui Wen |
|
| TA01 | Transfer of patent application right | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170510 |
|
| RJ01 | Rejection of invention patent application after publication |