CN110604784A - Traditional Chinese medicine composition with remarkable alopecia prevention effect and application of traditional Chinese medicine composition in hair growth - Google Patents
Traditional Chinese medicine composition with remarkable alopecia prevention effect and application of traditional Chinese medicine composition in hair growth Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition with a remarkable alopecia prevention effect and application thereof in hair growth, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 2-5 parts of lucid ganoderma, 10-20 parts of prepared rehmannia root, 10-15 parts of Chinese yam, 10-20 parts of donkey-hide gelatin, 10-20 parts of medlar, 5-15 parts of peach kernel, 15-20 parts of tuckahoe, 5-10 parts of American ginseng, 20-25 parts of dwarf lilyturf tuber, 10-15 parts of Chinese date and 10-20 parts of astragalus root. The traditional Chinese medicine composition has a remarkable effect on alopecia caused by various reasons, particularly seborrheic alopecia.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with remarkable effects of preventing alopecia and white hair and application thereof in hair growth.
Background
The modern people lead to the rapid increase of the number of the alopecia and the white hair and the trend towards the youth due to a plurality of factors such as the accelerated pace of life, the increased working pressure, the overdraft of energy, the environmental pollution and the like, thereby not only bringing adverse effects to the working life of patients, but also causing heavy psychological pressure to the patients. Generally speaking, alopecia is more prevalent in men than in women.
The factors causing alopecia are many, and according to the analysis of the traditional Chinese medicine, the traditional Chinese medicine considers that the main causes of the alopecia are self body deficiency and wind evil invasion, and the main causes are liver and kidney deficiency and qi and blood deficiency. The hair is remained in the blood and the kidney is lustered, so that the hair is vigorous if the kidney has strong function, and the liver and kidney are insufficient, so that the alopecia can be caused. The reason why qi and blood should be supplemented is that the hair roots are hair follicles, which supply nutrition to the hair, and the hair follicles supply various nutrients through peripheral blood vessels, so that if the blood flow of the head is insufficient or the blood vessels are small, alopecia is caused, and the main reason of alopecia is caused.
The categories of hair loss mainly include: seborrheic alopecia, alopecia areata, hereditary alopecia, nutritional disorder alopecia, chemotherapy, senile alopecia, etc. Seborrheic alopecia is caused by imbalance between yin and yang of liver and kidney, especially deficiency of kidney yin, and is closely related to damp-heat. Alopecia areata is caused by liver and kidney deficiency, and wind and blood stasis. Combining a plurality of Chinese literatures, the root of the traditional Chinese medicine for preventing alopecia lies in: tonify liver and kidney, and nourish qi and blood.
Because western medicines have strong side effects, are painful to operate and treat and are expensive, how to treat alopecia becomes a mysterious study, and because no real reliable product is available for solving the pain point of the problem, the market for preventing alopecia becomes a huge market with 2 hundred million people demands and 4000 hundred million business opportunities. The traditional Chinese medicine treatment has the advantages of mild property of medicinal components, small side effect, convenient taking, low price and the like, and is more advantageous in the treatment of preventing alopecia.
Disclosure of Invention
The invention aims to overcome the defects of the existing anti-hair loss treatment technology, provides a traditional Chinese medicine composition with good anti-hair loss and white hair effects and application thereof in hair growth, and aims to provide a reliable and efficient medical technical means for anti-hair loss treatment and serve the society.
The technology comprises the following main contents:
a traditional Chinese medicine composition with a remarkable alopecia prevention effect is composed of the following raw materials in parts by weight: 2-5 parts of lucid ganoderma, 10-20 parts of prepared rehmannia root, 10-15 parts of Chinese yam, 10-20 parts of donkey-hide gelatin, 10-20 parts of medlar, 5-15 parts of peach kernel, 15-20 parts of tuckahoe, 5-10 parts of American ginseng, 20-25 parts of dwarf lilyturf tuber, 10-15 parts of Chinese date and 10-20 parts of astragalus root.
The preferable formula of the raw materials is as follows: 3 parts of lucid ganoderma, 18 parts of prepared rehmannia root, 7 parts of Chinese yam, 13 parts of donkey-hide gelatin, 10 parts of medlar, 13 parts of peach kernel, 18 parts of tuckahoe, 5 parts of American ginseng, 15 parts of dwarf lilyturf tuber, 15 parts of Chinese date and 13 parts of astragalus root.
The main effective component of the scutellaria baicalensis is baicalin, which can promote the secretion of hair papilla cells and has obvious growth promoting effect on mouse tentacle hair follicles cultured in vitro. The scutellaria water extract has obvious promotion effect on cell proliferation, melanin generation and tyrosinase activity.
The Lycium plant has various fluorigenic activities, and mainly comprises activities of oxidation resistance, liver protection, neuroprotection, anti-tumor, anti-inflammatory and the like. The flavonoids are main anti-oxidation components in the medlar, and the flavonoid glycosides in the medlar mainly take kaempferol and quercetin as mother nucleuses.
The ganoderan can remarkably improve the cell survival rate, obviously reduce the positive staining rate of beta-galactosidase, reduce cells in G0/G1 phase, increase cells in S phase, and effectively protect vascular endothelial cells.
The total saponins of the stems and leaves of the American ginseng can protect the damaged myocardial tissues in the non-ischemic area after myocardial infarction by means of anti-inflammation, vascular endothelium protection, energy metabolism regulation and the like. The result of the extraction of the American ginseng total flavone and the effect of the American ginseng total flavone on eliminating hydroxyl free radicals shows that the American ginseng extract contains effective components with the capacity of eliminating the hydroxyl free radicals (. OH) and has certain eliminating effect.
The flavone and glucoside substances in fructus Jujubae can relax blood vessel, antagonize platelet activating factor, scavenge free radicals, and inhibit peroxidation of polyunsaturated fatty acid on biological membrane.
The Chinese yam proteoglycan has obvious in-vitro antioxidation, and the in-vitro antioxidation capability of the Chinese yam proteoglycan is positively correlated with the proteoglycan concentration. Rhizoma Dioscoreae can significantly improve activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) in brain, and reduce content of oxidation product Malondialdehyde (MDA).
The donkey-hide gelatin can effectively improve hematopoietic microenvironment. The components of donkey-hide gelatin are similar to stem cell microenvironment substances in embryonic tissues, and the substances play a role in the whole process of proliferation and development from totipotent stem cells to various lineages of blast cells, regulate hematopoietic microenvironment and enrich blood. The effective components of colla Corii Asini can be skin extracellular matrix components, and they have the characteristics of heterologous inducer, and can act on stem cells to further proliferate and differentiate
The medicinal components of the traditional Chinese medicine composition with the significant alopecia prevention effect are mainly used for treating alopecia through the following mechanisms: replenishing qi, nourishing blood, dilating scalp capillary, improving microcirculation, and activating hair mother cell; promoting the proliferation of hair mother cells, improving the activity of tyrosinase and promoting the formation of melanin; protecting vascular endothelial cells, and inhibiting vascular endothelial cell aging; free radical in vivo scavenging, antioxidant, antiinflammatory, etc.
The traditional Chinese medicine composition with the significant alopecia prevention effect is wide in application, and the alopecia types are treated as follows:
1) seborrheic alopecia;
2) alopecia areata;
3) alopecia caused by excessive mental stress;
4) alopecia due to endocrine dyscrasia;
5) postpartum alopecia;
6) alopecia due to malnutrition;
7) chemotherapy-induced alopecia;
8) hair loss due to hair damage;
the Chinese medicinal composition with the remarkable alopecia preventing effect is used by soaking in boiled water and directly drinking. The traditional Chinese medicine has the characteristics of mild property of medicinal components, small side effect, convenient administration and the like, and has more advantages in alopecia prevention and treatment.
Detailed Description
The invention is further illustrated by the following examples.
Examples 1
Weighing 3 parts of lucid ganoderma, 18 parts of prepared rehmannia root, 7 parts of Chinese yam, 13 parts of donkey-hide gelatin, 10 parts of medlar, 13 parts of peach kernel, 18 parts of tuckahoe, 5 parts of American ginseng, 15 parts of dwarf lilyturf tuber, 15 parts of Chinese date and 13 parts of astragalus.
The additive of the traditional Chinese medicine composition with the significant alopecia preventing effect comprises: perfumes, ph regulators, humectants, surfactants, preservatives, antimicrobials, stabilizers, excipients, and mixtures thereof.
The application method of the traditional Chinese medicine composition with the significant alopecia prevention effect is mainly soaking in boiled water, and the traditional Chinese medicine composition is directly drunk 2 times a day.
EXAMPLES example 2
Clinical validation
Case 1
Plum, male, now 52 years old, seborrheic alopecia. After the traditional Chinese medicine composition in the embodiment example 1 is drunk 2-3 times a day and is insisted on treatment for 6 months, the grease secretion of the head is obviously reduced, the hair begins to grow in the middle of the scalp, the hair gradually becomes thick, and the recovery is almost complete.
Case 2
Zhangqi, male, now 28 years old, in recent years, the hair is seriously lost due to the work pressure and emotional tension. The traditional Chinese medicine composition in the embodiment 1 is drunk 2-3 times a day, after the treatment is insisted for 8 months, new hair grows out of the head and becomes dense gradually, and no recurrence is caused after the traditional Chinese medicine composition is used for 1 year.
Case 3
Yang Shi, female, 35 years old, postpartum alopecia. With the traditional Chinese medicine composition in the embodiment example 1, the hair on the head is gradually thickened and is obviously improved after the traditional Chinese medicine composition is drunk for 2-3 times every day and the treatment is insisted for 3 months.
Clinical observation is carried out on nearly 100 alopecia patients by applying the traditional Chinese medicine composition in the embodiment 1, wherein the patients come from different regions, the ages of the patients range from 20 to 60 years, 65 male patients and 35 female patients. The alopecia types include seborrheic alopecia, alopecia areata, malnutritional alopecia, postpartum alopecia, alopecia caused by high mental stress, and the like. The application method is soaking in boiled water, and directly drinking the tea 2-3 times a day, with 30 days of each treatment course. According to clinical observation, the alopecia of patients is obviously improved by 87 cases, slightly improved by 7 cases and ineffective by 6 cases.
Clinical tests prove that the traditional Chinese medicine composition with the significant anti-hair loss effect has good treatment effect on hair loss caused by various reasons, and the traditional Chinese medicine is easier to accept by wide patients due to the characteristics of mild medicinal components, small side effect, convenient administration, low price and the like, and has great potential in the anti-hair loss market.
Claims (6)
1. A traditional Chinese medicine composition with a remarkable alopecia prevention effect is characterized by being prepared from the following medicinal material extracts: ganoderma lucidum, radix rehmanniae Preparata, rhizoma Dioscoreae, colla Corii Asini, fructus Lycii, semen Persicae, Poria, radix Panacis Quinquefolii, radix Ophiopogonis, fructus Jujubae, and radix astragali.
2. The traditional Chinese medicine composition with the significant alopecia preventing effect according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 2-5 parts of lucid ganoderma, 10-20 parts of prepared rehmannia root, 10-15 parts of Chinese yam, 10-20 parts of donkey-hide gelatin, 10-20 parts of medlar, 5-15 parts of peach kernel, 15-20 parts of tuckahoe, 5-10 parts of American ginseng, 20-25 parts of dwarf lilyturf tuber, 10-15 parts of Chinese date and 10-20 parts of astragalus root.
3. The traditional Chinese medicine composition with the significant alopecia preventing effect according to claim 2, characterized in that the composition is composed of the following raw materials in parts by weight: 3 parts of lucid ganoderma, 18 parts of prepared rehmannia root, 7 parts of Chinese yam, 13 parts of donkey-hide gelatin, 10 parts of medlar, 13 parts of peach kernel, 18 parts of tuckahoe, 5 parts of American ginseng, 15 parts of dwarf lilyturf tuber, 15 parts of Chinese date and 13 parts of astragalus root.
4. The traditional Chinese medicine composition with the significant alopecia preventing effect according to claim 1, characterized in that the composition contains additives.
5. The Chinese herbal medicine composition with remarkable alopecia preventing effect according to claim 4, characterized in that the composition contains additives comprising: perfumes, ph regulators, humectants, surfactants, preservatives, antimicrobials, stabilizers, excipients, and mixtures thereof.
6. The traditional Chinese medicine composition with the significant alopecia preventing effect according to claim 1, which is characterized in that the application method of the traditional Chinese medicine composition is soaking in boiled water and directly drinking.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087267A (en) * | 1992-11-23 | 1994-06-01 | 梅晓春 | A kind of prescription for the treatment of seborrheic alopecia |
| CN104706811A (en) * | 2013-12-11 | 2015-06-17 | 王焱 | Hair-growth traditional Chinese medicine formula |
| CN107184892A (en) * | 2017-05-26 | 2017-09-22 | 云南滇药医药健康产业有限公司 | Composition with blood-nourishing black hair effect and preparation method thereof |
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2018
- 2018-05-28 CN CN201810561019.1A patent/CN110604784A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087267A (en) * | 1992-11-23 | 1994-06-01 | 梅晓春 | A kind of prescription for the treatment of seborrheic alopecia |
| CN104706811A (en) * | 2013-12-11 | 2015-06-17 | 王焱 | Hair-growth traditional Chinese medicine formula |
| CN107184892A (en) * | 2017-05-26 | 2017-09-22 | 云南滇药医药健康产业有限公司 | Composition with blood-nourishing black hair effect and preparation method thereof |
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Application publication date: 20191224 |