CN110582489A - Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 - Google Patents

Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 Download PDF

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CN110582489A
CN110582489A CN201880028332.7A CN201880028332A CN110582489A CN 110582489 A CN110582489 A CN 110582489A CN 201880028332 A CN201880028332 A CN 201880028332A CN 110582489 A CN110582489 A CN 110582489A
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compound
ring
reaction
cancer
group
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CN110582489B (zh
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赵焰平
王红军
李功
姜媛媛
李想
刘彬
仲伟婷
刘凯
李发洁
周丽莹
刘亚男
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Mitralign Inc
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Mitralign Inc
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Priority claimed from PCT/CN2017/104290 external-priority patent/WO2019000682A1/zh
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Priority to CN202311291547.7A priority Critical patent/CN117343049A/zh
Priority to CN202010118186.6A priority patent/CN111217797B/zh
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Abstract

Description

PCT国内申请，说明书已公开。

Claims (18)

  1. PCT国内申请，权利要求书已公开。
CN201880028332.7A 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 Active CN110582489B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202311291547.7A CN117343049A (zh) 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
CN202010118186.6A CN111217797B (zh) 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途

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Application Number Priority Date Filing Date Title
CNPCT/CN2017/091085 2017-06-30
CNPCT/CN2017/091085 2017-06-30
PCT/CN2017/104290 WO2019000682A1 (zh) 2017-06-30 2017-09-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
CNPCT/CN2017/104290 2017-09-29
CN201711089580 2017-11-08
CN2017110895806 2017-11-08
PCT/CN2018/093713 WO2019001572A1 (zh) 2017-06-30 2018-06-29 Rho 相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途

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CN202010118186.6A Division CN111217797B (zh) 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途

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CN202010118186.6A Active CN111217797B (zh) 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
CN201880028332.7A Active CN110582489B (zh) 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途

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CN202010118186.6A Active CN111217797B (zh) 2017-06-30 2018-06-29 Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途

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US (2) US11390609B2 (zh)
EP (1) EP3647311B1 (zh)
JP (2) JP7311228B2 (zh)
KR (1) KR102585860B1 (zh)
CN (3) CN117343049A (zh)
AU (2) AU2018294054B2 (zh)
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