CN110475875B - 通过分析甲基化dna检测结肠瘤形成 - Google Patents
通过分析甲基化dna检测结肠瘤形成 Download PDFInfo
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- CN110475875B CN110475875B CN201880012946.6A CN201880012946A CN110475875B CN 110475875 B CN110475875 B CN 110475875B CN 201880012946 A CN201880012946 A CN 201880012946A CN 110475875 B CN110475875 B CN 110475875B
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410745296.3A CN119193824A (zh) | 2017-01-27 | 2018-01-26 | 通过分析甲基化dna检测结肠瘤形成 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762451327P | 2017-01-27 | 2017-01-27 | |
| US62/451,327 | 2017-01-27 | ||
| US201862622107P | 2018-01-25 | 2018-01-25 | |
| US62/622,107 | 2018-01-25 | ||
| PCT/US2018/015535 WO2018140781A1 (en) | 2017-01-27 | 2018-01-26 | Detection of colon neoplasia by analysis of methylated dna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410745296.3A Division CN119193824A (zh) | 2017-01-27 | 2018-01-26 | 通过分析甲基化dna检测结肠瘤形成 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110475875A CN110475875A (zh) | 2019-11-19 |
| CN110475875B true CN110475875B (zh) | 2024-06-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880012946.6A Active CN110475875B (zh) | 2017-01-27 | 2018-01-26 | 通过分析甲基化dna检测结肠瘤形成 |
| CN202410745296.3A Pending CN119193824A (zh) | 2017-01-27 | 2018-01-26 | 通过分析甲基化dna检测结肠瘤形成 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202410745296.3A Pending CN119193824A (zh) | 2017-01-27 | 2018-01-26 | 通过分析甲基化dna检测结肠瘤形成 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11118228B2 (enExample) |
| EP (1) | EP3574110A4 (enExample) |
| JP (3) | JP7289264B2 (enExample) |
| KR (2) | KR102667067B1 (enExample) |
| CN (2) | CN110475875B (enExample) |
| AU (2) | AU2018211956B2 (enExample) |
| CA (1) | CA3049459A1 (enExample) |
| WO (1) | WO2018140781A1 (enExample) |
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| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| ES2812753T3 (es) | 2014-03-31 | 2021-03-18 | Mayo Found Medical Education & Res | Detección de neoplasma colorectal |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| CN107532124B (zh) | 2015-03-27 | 2022-08-09 | 精密科学公司 | 检测食管疾病 |
| AU2016315924B2 (en) * | 2015-08-31 | 2022-08-25 | Exact Sciences Corporation | Detecting gastric neoplasm |
| CN108350485A (zh) | 2015-10-30 | 2018-07-31 | 精密科学发展有限责任公司 | 血浆dna的多重扩增检测测定以及分离和检测 |
| US10370726B2 (en) * | 2016-04-14 | 2019-08-06 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasia |
| US20170321286A1 (en) | 2016-05-05 | 2017-11-09 | Exact Sciences Corporation | Detection of lung neoplasia by amplification of rna sequences |
| WO2017192221A1 (en) | 2016-05-05 | 2017-11-09 | Exact Sciences Corporation | Detection of lung neoplasia by analysis of methylated dna |
| EP3488003B1 (en) * | 2016-07-19 | 2023-10-25 | Exact Sciences Corporation | Nucleic acid control molecules from non-human organisms |
| ES2902174T3 (es) * | 2016-07-19 | 2022-03-25 | Exact Sciences Dev Co Llc | ADN de control metilado |
| CN110475875B (zh) | 2017-01-27 | 2024-06-25 | 精密科学公司 | 通过分析甲基化dna检测结肠瘤形成 |
| CN111655869B (zh) | 2017-11-30 | 2024-06-28 | 梅约医学教育与研究基金会 | 检测乳腺癌 |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| US20220162709A1 (en) * | 2019-04-03 | 2022-05-26 | Mayo Foundation For Medical Education And Research | Detecting pancreatic ductal adenocarcinoma in plasma |
| CN109811035A (zh) * | 2019-04-11 | 2019-05-28 | 中国人民解放军第四军医大学 | 一种肠道脱落细胞目标基因启动子甲基化检测的方法及试剂盒 |
| US11396679B2 (en) * | 2019-05-31 | 2022-07-26 | Universal Diagnostics, S.L. | Detection of colorectal cancer |
| US11001898B2 (en) | 2019-05-31 | 2021-05-11 | Universal Diagnostics, S.L. | Detection of colorectal cancer |
| CN110317874A (zh) * | 2019-07-19 | 2019-10-11 | 江苏元丞生物科技有限公司 | Vav3基因甲基化检测试剂盒及其应用 |
| KR20220092561A (ko) | 2019-10-31 | 2022-07-01 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 난소암 검출 |
| US11898199B2 (en) | 2019-11-11 | 2024-02-13 | Universal Diagnostics, S.A. | Detection of colorectal cancer and/or advanced adenomas |
| CN112662765A (zh) * | 2020-03-17 | 2021-04-16 | 博尔诚(北京)科技有限公司 | 一种检测6种中国高发癌症的探针组合物 |
| CA3173044A1 (en) * | 2020-03-20 | 2021-09-23 | Singlera Health Technologies (Shanghai) Ltd. | Methods and kits for screening colorectal neoplasm |
| CN111961721B (zh) * | 2020-04-15 | 2022-06-07 | 南方医科大学 | 血浆sfmbt2基因甲基化在结直肠癌中转移预测及动态监测中的应用 |
| CN115605138A (zh) * | 2020-04-17 | 2023-01-13 | 精密科学公司(Us) | 可摄取取样装置 |
| US12467096B2 (en) | 2020-05-15 | 2025-11-11 | Universal Diagnostics, S.A. | Methods and systems for identifying methylation biomarkers |
| WO2022002424A1 (en) | 2020-06-30 | 2022-01-06 | Universal Diagnostics, S.L. | Systems and methods for detection of multiple cancer types |
| CN112430657B (zh) * | 2020-10-27 | 2022-09-09 | 哈尔滨医科大学 | 结直肠癌相关的甲基化标志物以及用于检测结直肠癌的试剂盒 |
| US11821045B2 (en) | 2021-04-13 | 2023-11-21 | Geninus Inc. | Colorectal cancer-specific methylation biomarkers for diagnosing colorectal cancer |
| CN113454243B (zh) * | 2021-04-23 | 2025-03-21 | 华大数极生物科技(深圳)有限公司 | 用于结直肠癌检测的组合物、试剂盒及应用 |
| US20220349009A1 (en) * | 2021-04-23 | 2022-11-03 | Mayo Foundation For Medical Education And Research | Detecting esophageal disorders |
| CN115433778B (zh) * | 2021-06-02 | 2023-06-16 | 武汉艾米森生命科技有限公司 | 一种用于检测结直肠癌或结直肠腺瘤相关基因甲基化的检测试剂、试剂盒及其应用 |
| WO2023017001A1 (en) * | 2021-08-09 | 2023-02-16 | Epigenomics Ag | Improved methods for detecting colorectal cancer |
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| EP4582561A1 (en) * | 2022-09-02 | 2025-07-09 | BGI Genomics Co., Limited | Combination of differentially methylated regions, kit, and use thereof |
| WO2024045160A1 (zh) * | 2022-09-02 | 2024-03-07 | 深圳华大基因股份有限公司 | Oplah基因的差异性甲基化区域、试剂盒和用途 |
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