CN110384794A - A kind of ointment for female vulva hickie - Google Patents
A kind of ointment for female vulva hickie Download PDFInfo
- Publication number
- CN110384794A CN110384794A CN201810361770.7A CN201810361770A CN110384794A CN 110384794 A CN110384794 A CN 110384794A CN 201810361770 A CN201810361770 A CN 201810361770A CN 110384794 A CN110384794 A CN 110384794A
- Authority
- CN
- China
- Prior art keywords
- hickie
- ointment
- vulva
- female vulva
- bamboo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Abstract
The present invention provides a kind of ointment for female vulva hickie, it is made of the raw material of following weight ratio: the red bacterium of bamboo, frutus cnidii, kuh-seng, propolis, acetic acid chlorhexidine, biologically active peptide, after product of the invention is applied to female vulva, it can go deep into skin texture rapidly, it is effectively antipruritic, destroy the living environment of harmful bacteria, improve antibacterial ability, and Chinese medicine combination drug effect is mildly non-stimulated, patient is after using 7 days, the vulva surface surface of a wound starts to heal, and pigment starts to precipitate after 10-15 days, and hickie illness is eased.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of ointment for female vulva hickie.
Background technique
Female vulva hickie is also known as that vulva white is damaged or dystrophy of vulva, nosogenesis be vulva local nerve with
Lesion tissue caused by angiodystrophia and pigment alteration, clinically by external cause local skin and mucous membrane denaturation or atrophic disease
Disease is referred to as leukoplakia vulvae.Unbearably for pudendal pruritus, local skin is dry for the Symptoms of leukoplakia vulvae, bleaches and plump, has
Pain burning sensation.It is clinically laser, the methods of microwave, but the method only acts on to the traditional therapy of leukoplakia vulvae
Skin surface is unable to reach the purpose of radical cure, also has high energy to gather ultrasound, local block therapy etc. at present and takes effect apparent therapy,
But such therapy medication is all hormone medicine, patient is very careful to the selection of hormone medicine therefore this in recent years
Method is not appropriate for being used for a long time.At present to the treatment of leukoplakia vulvae in addition to there are also the methods of medications for surgical treatment, still
Long-term stubborn disease this for leukoplakia vulvae, the effect is unsatisfactory, ailing to torment patient throughout the year.
Summary of the invention
According to above-mentioned elaboration, the purpose of the present invention is to provide a kind of Chinese medicine composition sprays, are used for female vulva hickie
Treatment.
Technical solution provided by the invention: a kind of ointment for female vulva hickie is the raw material by following weight ratio
It is made: the red bacterium 15%~20% of bamboo, frutus cnidii 3%~5%, propolis 1%~3%, kuh-seng 1%~3%, acetic acid chlorhexidine
0.20-0.40%, biologically active peptide 1%~3%.
In above-mentioned technical proposal, the red bacterium 20% of bamboo, kuh-seng 1%, frutus cnidii 3%, propolis 1%, acetic acid chlorhexidine 0.30%,
Biologically active peptide 1%.
A kind of preparation method of ointment for female vulva hickie provided by the invention is: by the raw material:
The red bacterium of bamboo, frutus cnidii, propolis, kuh-seng, acetic acid chlorhexidine, biologically active peptide mix lotion.
The extraction of Chinese medicine uses aqueous solvent extracting mode, the effective component of extraction.
For the present invention based on pathogenesis and treatment principle to female vulva disease, compatibility is reasonable, scientific, is largely faced
Bed verifying, without any toxicity and side effects, after product of the invention is applied to female vulva, can go deep into rapidly skin texture, and effectively antipruritic, destruction has
The living environment of evil bacterium, improves antibacterial ability, and Chinese medicine combination drug effect is mildly non-stimulated, and patient is after using 7 days, vulva
The surface surface of a wound starts to heal, and pigment starts to precipitate after 10-15 days, and hickie illness is eased.
Specific embodiment
Technical solution of the present invention is clearly and completely described below, it is clear that described embodiment is only this
Invention a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art exist
Every other embodiment obtained under the premise of creative work is not made, shall fall within the protection scope of the present invention.
Compatibility of drugs of the invention is reasonable, and component effect is:
The red bacterium of bamboo, property is pungent, puckery, puts down.Enter Liver Channel.There are detoxifying and relieving itching, torr sore myogenic.
Kuh-seng, bitter is cold in nature, return heart, liver, stomach, large intestine, bladder meridian, has heat-clearing, eliminating dampness, and the effect of desinsection has only negative
The benefits of itching.
Propolis has the effect of moisturizing myogenic, anti-inflammatory analgetic.
Frutus cnidii, warm-natured, bitter return kidney channel, and the present invention utilizes antibacterial, antimycotic, anti-inflammatory effect.
Acetic acid chlorhexidine plays bactericidal effect.
Biologically active peptide adjusts the physiological function of internal cell, activates related enzyme system in vivo, promotes the logical of intermediate supersession film
The effect of permeability.
According to above-mentioned component and compatibility principle analysis, the present invention, following embodiment is disclosed.
Embodiment:
Take: a kind of ointment for female vulva hickie, is to be made from the following raw materials in parts by weight:
The frutus cnidii that bamboo parasitic fungus extract 200g that hypocrellin effective content is 20%, frutus cnidii effective content are 10%
The propolis extract that shrubby sophora extract 10g that extract 30g, matrine effective content are 98%, propolis effective content are 10%
10g, acetic acid chlorhexidine 0.3g, biologically active peptide 10g are stirred evenly, and the last weight of mixture is 260.3g.
In use, Chinese medicine composition lotion is uniformly applied to female vulva affected part surface by patient.
To show fungistatic effect of the invention, the embodiment of the present invention does bacteriostatic test:
One, equipment
1, test strain: Escherichia coli (8099) are cultivated 9 generations, Candida albicans (ATCC10231), culture 9 generations, golden yellow
Color staphylococcus (ATCC6538) cultivated for 9 generations, is provided by Chinese Culture Collection Center.
2, general English agar medium, sabouraud's agar are provided by Beijing road and bridge technology Co., Ltd.
3/0.03mol/L phosphate buffer solution (PBS)
4, carrier: filter paper (2.0cm × 3.0cm), sterile measuring pipette, sterilized petri dishes, sterile test tube, constant incubator
Deng
Two, sample is the present embodiment 5g, is put into sterile mortar grinding, crushes, mixes, is put into sterilized petri dishes and is directly pressed down
Bacterium test.
Three, method is according to GB15979-200 " Disposable Sanitary Accessory sanitary standard " appendix C 4, " disinfection technology rule
Model " 2002 editions 2.1.8 test.
Bacteriostatic test is carrier test, and 20 DEG C ± 1 DEG C of test temperature, test is repeated 3 times.
Four, result
Under conditions of 20 DEG C ± 2 DEG C of test temperature, embodiment is to Escherichia coli, Candida albicans, Staphylococcus aureus
Bacterium inhibitory effect.
The embodiment of the present invention is shown in Table 1 to the inhibitory effect inspection of staphylococcus aureus；
The inhibitory effect of 1 staphylococcus aureus of table
The embodiment of the present invention is shown in Table 2 for the inhibitory effect inspection of Candida albicans.
The inhibitory effect of 2 Candida albicans of table
The embodiment of the present invention is shown in Table 3 to the inhibitory effect inspection of Escherichia coli；
The inhibitory effect of 3 Escherichia coli of table
The conclusion tested above, for embodiment to Escherichia coli, Candida albicans, staphylococcus aureus inhibiting rate are reachable
90% or more.
To show clinical application effect of the invention, the present invention is proved through clinical and experimental study: to the composition of embodiment
Crowd through age groups carries out test effect, and through testing, this product has good effect to female vulva hickie, such as suffers from
7 days beginning vulva surface of a wound start to heal person after use, and there are vulvas to have the symptoms such as itch, pain calcination equal before use by patient
It obtains biggish improvement after using 10-15 days, when use after cleaning vulva, this product is taken uniformly to be applied to uncomfortable position.Daily
1-2 times.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (3)
1. a kind of ointment for female vulva hickie, it is characterised in that: be made of the raw material of following weight ratio: the red bacterium of bamboo
15%~20%, frutus cnidii 3%~5%, propolis 1%~3%, kuh-seng 1%~3%, acetic acid chlorhexidine 0.20-0.40%, life
Object active peptide 1%~3%.
2. a kind of ointment for female vulva hickie according to claim 1, it is characterised in that: be by following weight ratio
Raw material be made: the red bacterium 20% of bamboo, kuh-seng 1%, frutus cnidii 3%, propolis 1%, acetic acid chlorhexidine 0.30%, biologically active peptide
1%, the red bacterium of the raw material bamboo, frutus cnidii, acetic acid chlorhexidine mix with the kuh-seng of equivalent weight, biologically active peptide.
3. a kind of ointment for female vulva hickie according to claims 1 and 2, it is characterised in that: the ointment system
Preparation Method is that the red bacterium of bamboo, frutus cnidii, kuh-seng, acetic acid chlorhexidine, biologically active peptide is taken to pulverize using grinder, and bee is added
Lotion is made in glue.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810361770.7A CN110384794A (en) | 2018-04-20 | 2018-04-20 | A kind of ointment for female vulva hickie |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810361770.7A CN110384794A (en) | 2018-04-20 | 2018-04-20 | A kind of ointment for female vulva hickie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110384794A true CN110384794A (en) | 2019-10-29 |
Family
ID=68283669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810361770.7A Pending CN110384794A (en) | 2018-04-20 | 2018-04-20 | A kind of ointment for female vulva hickie |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110384794A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1284494A (en) * | 2000-08-22 | 2001-02-21 | 云南医药工业股份有限公司 | Bamboo parasitic fungus extract and its preparation and application |
| CN101991605A (en) * | 2010-11-12 | 2011-03-30 | 杨长辉 | Medicament for bactriostasis, protection and cleaning of vagina of human body and preparation method thereof |
| CN107510768A (en) * | 2016-06-15 | 2017-12-26 | 吴鹏飞 | A kind of draft bacteriostatic gel |
| CN107802825A (en) * | 2017-12-04 | 2018-03-16 | 陕西美芙康生物科技有限公司 | A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa |
| CN107812137A (en) * | 2017-10-25 | 2018-03-20 | 北京中蜜科技发展有限公司 | A kind of draft skin bacteriostatic gel of propolis-containing and preparation method thereof |
-
2018
- 2018-04-20 CN CN201810361770.7A patent/CN110384794A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1284494A (en) * | 2000-08-22 | 2001-02-21 | 云南医药工业股份有限公司 | Bamboo parasitic fungus extract and its preparation and application |
| CN101991605A (en) * | 2010-11-12 | 2011-03-30 | 杨长辉 | Medicament for bactriostasis, protection and cleaning of vagina of human body and preparation method thereof |
| CN107510768A (en) * | 2016-06-15 | 2017-12-26 | 吴鹏飞 | A kind of draft bacteriostatic gel |
| CN107812137A (en) * | 2017-10-25 | 2018-03-20 | 北京中蜜科技发展有限公司 | A kind of draft skin bacteriostatic gel of propolis-containing and preparation method thereof |
| CN107802825A (en) * | 2017-12-04 | 2018-03-16 | 陕西美芙康生物科技有限公司 | A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa |
Non-Patent Citations (3)
| Title |
|---|
| 张胜泉，等: "竹红菌治疗外阴白色病变(白斑)的组织变化研究―附13例治疗前后的组织学观查", 《云南医药》 * |
| 顾红媛: "竹红菌素软膏治疗外阴白斑病33例疗效观察", 《中国伤残医学》 * |
| 颜世明，等，主编，: "《美容与皮肤病外用妙方集》", 31 May 1995, 南京大学出版社 * |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191029 |