CN110352245A - 可分泌变体免疫调节蛋白和工程化细胞疗法 - Google Patents

可分泌变体免疫调节蛋白和工程化细胞疗法 Download PDF

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CN110352245A
CN110352245A CN201780078110.1A CN201780078110A CN110352245A CN 110352245 A CN110352245 A CN 110352245A CN 201780078110 A CN201780078110 A CN 201780078110A CN 110352245 A CN110352245 A CN 110352245A
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igsf
affinity
cell
cells
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R·斯旺森
M·科尔纳克尔
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Alpine Immune Sciences Inc
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Alpine Immune Sciences Inc
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CN201780078110.1A 2016-10-20 2017-10-20 可分泌变体免疫调节蛋白和工程化细胞疗法 Pending CN110352245A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662410827P 2016-10-20 2016-10-20
US62/410,827 2016-10-20
US201762475210P 2017-03-22 2017-03-22
US62/475,210 2017-03-22
US201762537921P 2017-07-27 2017-07-27
US62/537,921 2017-07-27
PCT/US2017/057743 WO2018075978A1 (en) 2016-10-20 2017-10-20 Secretable variant immunomodulatory proteins and engineered cell therapy

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CN110352245A true CN110352245A (zh) 2019-10-18

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CN201780078110.1A Pending CN110352245A (zh) 2016-10-20 2017-10-20 可分泌变体免疫调节蛋白和工程化细胞疗法

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US (1) US20200040059A1 (https=)
EP (2) EP3872180A1 (https=)
JP (1) JP2020500010A (https=)
KR (1) KR20190099194A (https=)
CN (1) CN110352245A (https=)
AU (1) AU2017345764A1 (https=)
CA (1) CA3040296A1 (https=)
IL (1) IL266045A (https=)
SG (1) SG11201903407XA (https=)
WO (1) WO2018075978A1 (https=)

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CN113087806A (zh) * 2019-12-31 2021-07-09 华东师范大学 靶向多种肿瘤的新型car-t细胞及其制备和方法
CN113308491A (zh) * 2021-05-25 2021-08-27 北京鼎成肽源生物技术有限公司 一种共表达nfat和人dnam-1蛋白的重组质粒、重组细胞及其构建方法和应用
WO2021197430A1 (en) * 2020-04-01 2021-10-07 Nanjing Legend Biotech Co., Ltd. Compositions and methods for reducing graft rejection in allogeneic cell therapy

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EA201891022A1 (ru) 2015-12-17 2019-01-31 Псайоксус Терапьютикс Лимитед Вирус, кодирующий антитело к комплексу tcr или фрагмент указанного антитела
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US11325948B2 (en) 2016-03-19 2022-05-10 Exuma Biotech Corp. Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
EP4706777A2 (en) 2016-04-15 2026-03-11 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
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US11471488B2 (en) 2016-07-28 2022-10-18 Alpine Immune Sciences, Inc. CD155 variant immunomodulatory proteins and uses thereof
US11834490B2 (en) 2016-07-28 2023-12-05 Alpine Immune Sciences, Inc. CD112 variant immunomodulatory proteins and uses thereof
GB201713765D0 (en) 2017-08-28 2017-10-11 Psioxus Therapeutics Ltd Modified adenovirus
CN119614520A (zh) 2016-08-29 2025-03-14 阿卡米斯生物公司 携带双特异性t细胞衔接器的腺病毒
EP3596114A2 (en) 2017-03-16 2020-01-22 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
JP2020511144A (ja) 2017-03-16 2020-04-16 アルパイン イミューン サイエンシズ インコーポレイテッド Ｐｄ−ｌ２バリアント免疫調節タンパク質及びその使用
WO2018201014A1 (en) 2017-04-28 2018-11-01 Five Prime Therapeutics, Inc. Methods of treatment with cd80 extracellular domain polypeptides
PL3630143T3 (pl) 2017-06-01 2023-10-30 Akamis Bio Limited Wirus onkolityczny i sposób
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KR102813968B1 (ko) 2017-10-10 2025-05-29 알파인 이뮨 사이언시즈, 인코포레이티드 Ctla-4 변이체 면역조절 단백질 및 이의 용도
SMT202600062T1 (it) 2017-10-18 2026-03-09 Alpine Immune Sciences Inc Proteine immunomodulatrici del ligando di icos variante e composizioni e metodi correlati
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JP2021514379A (ja) 2018-02-21 2021-06-10 ファイブ プライム セラピューティクス， インコーポレイテッド Ｂ７−ｈ４抗体製剤
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