CN110339315A - A kind of mongolian veterinary drug feed addictive and preparation method thereof for promoting ewe ovulation to produce twin lamb(s) - Google Patents

Abstract

The invention discloses the mongolian veterinary drug feed addictives and preparation method thereof that a kind of promotion ewe ovulation produces twin lamb(s), including Herba Epimedii and each 40 parts of actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort；Rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；Kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；Each 15 parts of Goat Placenta powder, deer blood meal, each 5 parts of nitre, Lygodium japonicum.The additive using non-stimulated non-antibiotics production without side-effects, have many advantages, such as efficiently, it is low toxicity, nonirritant, meeting the ovulation of promoting the sexual maturity of ewe, non-stimulated, without side-effects, harmonious object converts development trend from traditional chemical substance to animal；Additive main component derives from green plants and minerals between nature, compatible with phytophagous ewe vivo environment, degradation in vivo or can be metabolized as simple native compound, the final product cleared up in body is carbon dioxide and water.

Description

A kind of mongolian veterinary drug feed addictive and preparation method thereof for promoting ewe ovulation to produce twin lamb(s)

Technical field:

It promotes the sexual maturity ovulation field the present invention relates to farm animals, specially a kind of mongolian veterinary drug for promoting ewe ovulation to produce twin lamb(s) Feed addictive and preparation method thereof.

Background technique:

With the rapid development of economy, people's living standard is substantially improved, thus eat safe and healthy, nutrition has become The new Diet concept of people.For the mutton in the Inner Mongol, the features such as meat exquisiteness, low fat, low cholesterol, high protein, to get over The consumption to mutton is increased come more people, also have stimulated the development of sheep husbandry, but still it is increasingly high effectively to meet market The mutton consumption demand risen, therefore improving sheep raising industry development is research hotspot important at present, and reproductive trait is sheep raising production One of principal economic indicators of industry, the every tire litter size for increasing sheep is the effective measures for reducing production cost, improving production efficiency. Currently, the domestic mode for producing more lambs for increasing ewe, which mainly has directly to introduce a fine variety to have both at home and abroad, stablizes the genetic mother of more lambs Sheep variety, or by breeding, core reproducting herd is established, furthermore be exactly to carry out that more lambs is induced to handle using exogenous hormone.It introduces Various serious germs and virus etc. can be brought while new varieties, the breeding time is too long, and exogenous hormone inducing effect is all unstable, And it is easy to generate sheep side effect, excretory system disorder etc., therefore it is unfolded to ewe for environmentally protective mongolian veterinary drug Promote the sexual maturity Effect of Ovulation additive research be of great significance.

Summary of the invention:

The purpose of the present invention is in view of the drawbacks of the prior art, provide a kind of mongolian veterinary drug feeding of promotion ewe ovulation production twin lamb(s) Feed additives and preparation method thereof, to solve the problems, such as that above-mentioned background technique proposes.

To achieve the above object, the present invention provides following technological invention: a kind of mongolian veterinary drug for promoting ewe ovulation to produce twin lamb(s) Feed addictive, including monarch drug in a prescription, ministerial drug, adjutant and make medicine,

Monarch drug in a prescription: Herba Epimedii and each 40 parts of actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort；

Ministerial drug: rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；

Adjutant: kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；

Make medicine: each 15 parts of Goat Placenta powder, deer blood meal, each 5 parts of nitre, Lygodium japonicum.

A kind of preparation method for the mongolian veterinary drug feed addictive for promoting ewe ovulation to produce twin lamb(s),

Specific step is as follows；

Step 1: feeding, by each 40 parts of Herba Epimedii and actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort； Rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；Kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；Sheep Each 15 parts of placenta powder, deer blood meal, each 5 parts of raw material of nitre, Lygodium japonicum carries out cleaning, drying；

Step 2: the raw material that step 1 is taken is carried out to obtain mixture A after being crushed to the sieving mixing of 60-80 mesh；

Step 3: being put into pulverizing mill for the mixture A of step 2 and pulverize, and obtaining granularity is 300-400 purpose Mixture B is the additive.

The beneficial effects of the present invention are:

The additive identical with present chemical agent is to achieve the effect that ovulation produces twin lamb(s) by gavaging or feeding, no Same is that ewe ovulation produces the mongolian veterinary drug feed addictive of twin lamb(s) using non-stimulated non-antibiotics production without side-effects, meat The additive of the developments such as desert cistanche, fructus lycii, cynomorium songaricum, motherwort, Herba Epimedii, actinolite is from having the plant of substance of ovulating of promoting the sexual maturity Object tissue develops；Have many advantages, such as efficient, less toxic, nonirritant, meets the ovulation of promoting the sexual maturity of ewe from traditional chemicals Matter object non-stimulated to animal, without side-effects, harmonious converts development trend；Ewe ovulation is promoted to produce the mongolian veterinary drug feed addition of twin lamb(s) Agent main component derives from green plants and minerals between nature, compatible with phytophagous ewe vivo environment, can drop in vivo Simple native compound is solved or is metabolized as, for its effective component containing only three kinds of carbon, hydrogen, oxygen elements, that clears up in body is final Product is carbon dioxide and water, this promotes the sexual maturity extremely difficult in drug reach of ovulating chemically synthesized.

Specific embodiment:

The preferred embodiments of the present invention will be described in detail below, so that advantages and features of the invention can be easier to by this Field personnel understanding, so as to make a clearer definition of the protection scope of the present invention.

Embodiment: the present invention provides a kind of technological invention: a kind of mongolian veterinary drug feed addition for promoting ewe ovulation to produce twin lamb(s) Agent, including monarch drug in a prescription, ministerial drug, adjutant and make medicine,

Monarch drug in a prescription: Herba Epimedii and each 40 parts of actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort；

Ministerial drug: rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；

Adjutant: kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；

Make medicine: each 15 parts of Goat Placenta powder, deer blood meal, each 5 parts of nitre, Lygodium japonicum.

A kind of preparation method for the mongolian veterinary drug feed addictive for promoting ewe ovulation to produce twin lamb(s), specific step is as follows；

Step 1: feeding, by each 40 parts of Herba Epimedii and actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort； Rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；Kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；Sheep Each 15 parts of placenta powder, deer blood meal, each 5 parts of raw material of nitre, Lygodium japonicum carries out cleaning, drying；

Step 2: the raw material that step 1 is taken is carried out to obtain mixture A after being crushed to the sieving mixing of 60-80 mesh；

Step 3: being put into pulverizing mill for the mixture A of step 2 and pulverize, and obtaining granularity is 300-400 purpose Mixture B is the additive.

Application method:

Feed mixes clothes, grows up ewe every daily 10~15 parts, or drinking-water gavages, and breeds after being used in conjunction 7~15 days.Pass through this The mongolian veterinary drug feed addictive that the ewe ovulation of invention production produces twin lamb(s) has the function of promoting the sexual maturity, ovulates while producing twin lamb(s).

Monarch drug in a prescription: Herba Epimedii, enhancement hormone secretion can raise libido, and have the effect for promoting sexual function；Actinolite, it is main The effect wanted is exactly to carry out sterile treatment, improves sexual excitement；Motherwort, activating microcirculation and removing stasis medicinal, inducing diuresis for removing edema are clearing heat and detoxicating；Meat desert Rong, clinic are mainly used for treating kidney deficiency and negative blood failure, the qi and blood deficiency of Yin, infertility etc.；Fructus lycii promotes immune, removing freely The effects of base, liver protection, protection and improvement reproductive function；Cynomorium songaricum, big tonifying yin gas, benefiting essence-blood, benefit stool.

Ministerial drug: Radix Angelicae Sinensis has the effect of replenishing qi and blood, qi-restoratives damage；Rhizoma polygonati, Yin nourishing and lung moistening are invigorated the spleen and benefited qi, Zishen fill fine；Sea-buckthorn, Strengthening spleen and nourishing stomach, relieving cough and reducing sputum, promoting blood circulation scattered silt；Cortex cinnamomi treats the insufficiency of the kidney yang, the insufficiency of both the spleen and the kindey；Pomegranate, to hormone secretion and blood Circulation has certain stimulation, beneficial to the health of reproductive system and related organ；Asparagus fern, nourishing yin to moisten dryness, clearing lung-heat are promoted the production of body fluid；It is white Splendid achnatherum, astringing to arrest bleeding, detumescence and promoting granulation；Fructus piperis longi, warming spleen and stomach for dispelling cold, lower gas analgesic.

Adjutant: myrobalan, astringing lung-QI, puckery intestines, lower gas；Kaempferia galamga, regulating qi-flowing for relieving pain, strengthening the spleen and stomach, antibacterial anti-inflammatory；Excrementum pteropi, hemostasis, Promoting blood circulation to remove blood stasis；Cape jasmine, purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body.

Make medicine: Goat Placenta powder, enhancing physical strength, promotion hematopoiesis function, raising immunity etc.；Deer blood meal, energy benefiting essence-blood, yang-tonifying Gas, hemostasis；Nitre relieves pain, helps digestion；Lygodium japonicum, clearing heat and detoxicating, promoting diuresis for stranguria.Method foundation:

Increase ewe litter size number, influenced by number of eggs ovulated, in order to improve the lambing percentage of ewe, according to the illiteracy of collection Animal doctor's prescription, the monarch according to mongolian veterinary drug is theoretical, has screened additive of the present invention formula, while having done and having fed this mongolian veterinary drug Test after additive and the exogenous hormone-twin lamb hormone for having injected current clinic compared the lambing quantity of ewe, and then really Invention of the present invention is determined.

Composition of raw materials:

Monarch drug in a prescription: Herba Epimedii and each 40 parts of actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort；

Ministerial drug: rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；

Adjutant: kaempferia galamga, excrementum pteropi, cape jasmine and each 10 parts of myrobalan；

Make medicine: each 15 parts of Goat Placenta powder, deer blood meal, nitre and each 5 parts of Lygodium japonicum.

Preparation process:

1. above each taste medicine is weighed by prescribed dose respectively is crushed to 60-80 mesh, sieving for standby；

2. it particularly to be carried out to pulverizing mill again to pulverize；

3. sieving is uniformly mixed after the gained micronized processing of granularity 300-400 purpose.

Production invention verifying:

Currently, being the heat ovulation for controlling breeding sheep by artificial exogenous hormone promoting ewe ovulation to produce in twin lamb(s) Situation, but effect is unstable, easily generates side effect, excretory system disorder etc. to mother, therefore ovulate to this promotion ewe and produce twin lamb(s) Environmentally protective preparation carry out Experimental Comparison.

Materials and methods:

Test drug: twin lamb hormone derives from Lanzhou Livestock and Animal Drug Inst., Chinese Academy of Agricultural Science, ingredient (immunogene) For testosterone -3- carboxymethyl oxime bovine serum albumin(BSA), water aqua type is stored refrigerated.Each 40 parts of Herba Epimedii, actinolite, Herba Cistanches, fructus lycii Each 20 parts of son, cynomorium songaricum, motherwort；Each 20 parts of rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata, fructus piperis longi；Kaempferia galamga, five spirits Rouge, cape jasmine, each 10 parts of myrobalan；Each 15 parts of Goat Placenta powder, deer blood meal, each 5 parts of nitre, Lygodium japonicum.It is purchased from Anguo Shore Kang Yuan drink Piece Co., Ltd.

Experimental animal and grouping: selection Siziwang Banner Sunit ewes Zhong Yang Co., Ltd, investigated by breeding history and medical history, Clinical examination, the ewe (Sunit ewes) 160 of free from infection, parasitic disease and genital diseases are randomly divided into 4 groups, 1 group of work For control, feed addictive is not added and is directly fed with feed；After 2 groups of groupings after 20d, 200- is crushed to using this prescription The additive product that 300 mesh pulverize feeds 2 courses for the treatment of, a course for the treatment of 7d；After 3 groups of groupings after 20d, using the powder of this prescription The broken additive product to 60-80 mesh feeds 2 courses for the treatment of；4 groups of requirements according to twin lamb hormone ewe breed before 35d and 15d distinguishes 2 tail muscles and injects 1mL twin lamb hormone, then breeds simultaneously.Usually feeding is consistent with management.

As a result with analysis:

1 lambing situation of table

With column data shoulder, different letters indicate significant difference (P < 0.05), and letter is identical or indicates that difference is not shown without letter It writes (P < 0.05)

As it can be seen from table 1 of the present invention group and twin lamb hormone group double lamb rate are all significantly higher than control group (P < 0.05).But this Invention group lambing percentage is also significantly greater than control group, while double lamb rate also significantly has exceeded twin lamb hormone group, has absolutely proved the present invention Ovulation induction to produce twin lamb(s) effect obvious.

The single twin lamb(s) comparison of table 2

With column data shoulder, different letters indicate significant difference (P < 0.05), and letter is identical or indicates that difference is not shown without letter It writes (P < 0.05)

From table 2 it can be seen that the survival rate that the present invention invents is also very high, it is seen that this mongolian veterinary drug feeds serum after additive FSH concentration is shown in Table 2.In ultramicro grinding group, the formula by the additive before feeding additive is reasonable, can be used for sheep raising production In.

Clinical effectiveness test:

(1) trial drug

Twin lamb hormone, derives from Lanzhou Livestock and Animal Drug Inst., Chinese Academy of Agricultural Science, and ingredient (immunogene) is testosterone -3- Carboxymethyl oxime bovine serum albumin(BSA), water aqua type are stored refrigerated.Each 40 parts of Herba Epimedii, actinolite, Herba Cistanches, fructus lycii, cynomorium songaricum, Each 20 parts of motherwort；Each 20 parts of rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata, fructus piperis longi；Kaempferia galamga, excrementum pteropi, cape jasmine, Each 10 parts of myrobalan；Each 15 parts of Goat Placenta powder, deer blood meal, each 5 parts of nitre, Lygodium japonicum.It is purchased from the limited public affairs of Anguo Shore Kang Yuan medicine materical crude slice Department.Being crossed 60 meshes with common grinder and crushed is common coarse powder；Micro mist is that common coarse powder is carried out Ultramicro-powder with pulverizing mill again Gained (granularity 300-400 mesh) after broken.

(2) experimental animal

Siziwang Banner mountain peak cultivation cooperative society sheep core group Mongolia ewe is selected, selection has normal fertility, health It is disease-free, 2-5 years old, weight 30kg or more ewe only, after rejecting nonpregnant ewe and sick and weak sheep, be left 203, be randomly divided into 4 A test group is participated in the experiment ewe Unified number, is weighed and is registered, independent group, test group feeding and management condition and control group before lambing It is essentially identical.Ewe participate in the experiment in preliminary trial period tetrad seedling immunization inocultation, uses Albendazole expelling parasite before entering the winter.Test group is divided into control group (53), ultramicro grinding group (invention group 50 of the present invention), coarse powder group (present invention is crushed to 50,60-80 mesh), twin lamb hormone group (50) then unify conventinal breeding.

(3) test method

Additive 20d is not had to 1. raising by different preparations are grouped, after grouping, after 21d once a day, additive capacity is 10-15 parts/only, unified with 15 days, blank group does not have to product.

2. twin lamb hormone the 1st inoculation of progress in 35 days before breeding crosses 15 and carry out the 2nd injection, each dosage is 1ml。

3. breeding method is artificial insemination+natural mating, the breeding season is test 36d.

(4) result and analysis

3 ewe heat of table and fertilization situation

Note: the female entirely different expression significant difference (P < 0.05) of colleague's data shoulder marking-up indicates difference containing same letter Not significant (P > 0.05)

From table 3 it can be seen that the fine mongolian veterinary drug additive of the present invention either Oestrus rate or conception rate with compare There is significant difference, all without significant difference in terms of Oestrus rate and conception rate compared with twin lamb hormone.

4 ewe lambing of table and twin lamb(s) situation

Note: the female entirely different expression significant difference (P < 0.05) of colleague's data shoulder marking-up indicates difference containing same letter Not significant (P > 0.05)

It can be defined from table 4, mongolian veterinary drug additive micro mist and coarse powder, twin lamb hormone have production twin lamb(s) effect, but difference on effect Significantly, invention mongolian veterinary drug micro mist group effect of the present invention is best, can promote and apply.

The additive identical with present chemical agent is to achieve the effect that ovulation produces twin lamb(s) by gavaging or feeding, no Same is that ewe ovulation produces the mongolian veterinary drug feed addictive of twin lamb(s) using non-stimulated non-antibiotics production without side-effects, meat The additive of the developments such as desert cistanche, fructus lycii, cynomorium songaricum, motherwort, Herba Epimedii, actinolite is from having the plant of substance of ovulating of promoting the sexual maturity Object tissue develops；Have many advantages, such as efficient, less toxic, nonirritant, meets the ovulation of promoting the sexual maturity of ewe from traditional chemicals Matter object non-stimulated to animal, without side-effects, harmonious converts development trend；Ewe ovulation is promoted to produce the mongolian veterinary drug feed addition of twin lamb(s) Agent main component derives from green plants and minerals between nature, compatible with phytophagous ewe vivo environment, can drop in vivo Simple native compound is solved or is metabolized as, for its effective component containing only three kinds of carbon, hydrogen, oxygen elements, that clears up in body is final Product is carbon dioxide and water, this promotes the sexual maturity extremely difficult in drug reach of ovulating chemically synthesized.

The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention Shield.

Claims (2)

1. a kind of mongolian veterinary drug feed addictive for promoting ewe ovulation to produce twin lamb(s), including monarch drug in a prescription, ministerial drug, adjutant and make medicine, it is special Sign is:

Monarch drug in a prescription: Herba Epimedii and each 40 parts of actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort；

Ministerial drug: rhizoma polygonati, sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；

Adjutant: kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；

Make medicine: each 15 parts of Goat Placenta powder, deer blood meal, each 5 parts of nitre, Lygodium japonicum.

2. a kind of preparation method for the mongolian veterinary drug feed addictive for promoting ewe ovulation to produce twin lamb(s) as described in claim 1, special Sign is that specific step is as follows；

Step 1: feeding, by each 40 parts of Herba Epimedii and actinolite；Herba Cistanches, fructus lycii, cynomorium songaricum and each 20 parts of motherwort；Rhizoma polygonati, Sea-buckthorn, Radix Angelicae Sinensis, cortex cinnamomi, pomegranate, asparagus fern, the bletilla striata and each 20 parts of fructus piperis longi；Kaempferia galamga, excrementum pteropi, cape jasmine, each 10 parts of myrobalan；Goat Placenta Each 15 parts of powder, deer blood meal, each 5 parts of raw material of nitre, Lygodium japonicum carries out cleaning, drying；

Step 2: the raw material that step 1 is taken is carried out to obtain mixture A after being crushed to the sieving mixing of 60-80 mesh；

Step 3: being put into pulverizing mill for the mixture A of step 2 and pulverize, and obtains the mixing that granularity is 300-400 mesh Object B is the additive.