CN106309549A - Ultramicro-pulverised powder Chinese veterinary drug combination for promoting sow postpartum recovery and preparing method thereof - Google Patents
Ultramicro-pulverised powder Chinese veterinary drug combination for promoting sow postpartum recovery and preparing method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K9/00—Medicinal preparations characterised by special physical form
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Abstract
The invention discloses a ultramicro-pulverised powder Chinese veterinary drug combination for promoting sow postpartum recovery comprising by weight 40- 60 parts of leonurus, 40-60 parts of angelica sinensis, 20-30 parts of milkvetch root, 20-25 parts of herba epimedii, 10-15 parts of seed of cowherb, 10-15 parts of rhizoma chuanxiong and 5- 10 parts of honey-fried licorice root. The preparing method includes the steps of (1) mixing and smashing angelica sinensis and leonurus and smashing remaining materials separately; (2) superfinely grinding the mixed coarse powder of angelica sinensis and leonurus; (3) superfinely grinding remaining materials; (4) mixing ultramicro-pulverised powder. The invented product speeds up the growth of piglets, facilitates oestrus and reduces the postpartum comprehensive adverse symptoms.
Description
Technical field
The present invention relates to veterinary drug technical field, be specifically related to a kind of superfine powder herbal medicine promoting sow postpartum recovery and combine
Thing and preparation method thereof.
Background technology
During Swine Production, improve production efficiency, reduce production cost, be the target always pursued of pig industry.More come
The most enterprises of raising pigs have recognized that the importance of cost management, how effectively to manage cost, are that we are common
The realistic problem paid close attention to.The cost of pig industry is mainly by feed cost use, place colony house and personal management expense at present, and pig
The several respects such as the production efficiency of group are constituted.In addition to reducing feedstuff and production management's cost, improve Swine herd production efficiency and become fall
One of important channel of low production cost.
The puerperal sow of scientific and reasonable management can be greatly enhanced sow reproductive efficiency, thus also improves whole pig
The production capacity of field.But in actual production, the epidemic prevention and control before general emphasis childbirth and in childbirth, and sow after childbirth
The preventing and treating of feed management and some diseases in accordance with the law is the most often left in the basket.It is known that nursing sow is in whole Swine Production process
In, it is in most important status, but puerperal sow often due to be not taken prevents timely and effectively and treatment is arranged
Executing and take care of, the Health restoration speed making sow is slower.Additionally, along with the development of large-scale cultivation, the cultivation density of pig
Strengthen, add vaccine immunity injection and each stage turn that group etc. is various stress be continuous, particularly sow carries out position limiting fence for a long time
Raise, lack motion, cause body QI and blood to be retarded by silt, had a strong impact on the normal metabolism of body, caused prevention of sow constipation, uterus
Shrink unable, placenta retention, prolonged labor, cause fetal asphyxia dead, puerperal, there is breast in the not enough or milk poor water mass of milk
The postpartum syndromes such as inflammation.Once there is disease in sow, the most then to consume substantial amounts of medicine, and be in a bad way results even in
Death, causes serious economic loss.Therefore, the postpartum recovery particular importance of sow, existing treating method is in feedstuff
Adding some feed additives, for preventing and treat the some diseases in sow puerperal, but this medicine has selectivity to disease,
It is only capable for the treatment of one or both puerperal diseases, other diseases can not be accomplished prevention and the purpose for the treatment of；Also have some puerperal
Recovering additive granules relatively big, utilization rate of active components is low, the most in use there is consumption big, the defect that cost is high；
Also some postpartum recovery additive therapeutic effect is the best, has certain side effect.
Summary of the invention
For above-mentioned deficiency of the prior art, the invention provides beast in a kind of superfine powder promoting sow postpartum recovery
Drug composition and preparation method thereof, can effectively solve treatment target single, and effective rate of utilization is low, and cost is high, and therapeutic effect is the best,
The problem having side effect.
For achieving the above object, the technical solution adopted for the present invention to solve the technical problems is:
A kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the component of following weight portion: Herba Leonuri 40-60
Part, Radix Angelicae Sinensis 40-60 part, Radix Astragali 20-30 part, Herba Epimedii 20-25 part, Semen Vaccariae 10-15 part, Rhizoma Chuanxiong 10-15 part and Radix Glycyrrhizae Preparata
5-10 part.
Further, a kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the group of following weight portion
Point: Herba Leonuri 45-58 part, Radix Angelicae Sinensis 45-58 part, Radix Astragali 22-30 part, Herba Epimedii 21-24 part, Semen Vaccariae 12-15 part, Rhizoma Chuanxiong
12-15 part and Radix Glycyrrhizae Preparata 6-8 part.
Further, a kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the group of following weight portion
Point: Herba Leonuri 56 parts, Radix Angelicae Sinensis 55 parts, the Radix Astragali 26 parts, Herba Epimedii 23 parts, Semen Vaccariae 13 parts, Rhizoma Chuanxiong 13 parts and Radix Glycyrrhizae Preparata 8 parts.
The preparation method of the superfine powder Chinese veterinary medicinal composition of above-mentioned promotion sow postpartum recovery, comprises the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 20-30 mesh, is crushed to 80-the most again
100 mesh, then residual components is crushed to respectively 20-30 mesh, it is crushed to 80-100 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
Further, step (1) is first crushed to 24 mesh, is crushed to 80 mesh the most again.
Superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery that the present invention provides and preparation method thereof, has following
Beneficial effect:
(1) present invention is with promoting blood circulation to restore menstrual flow, the Herba Leonuri of the row's of squeezing lochia and replenishing and activating blood, the Radix Angelicae Sinensis of menstruction regulating and pain relieving as monarch drug, with
The Herba Epimedii of QI invigorating, the Radix Astragali of ascending up spleen-Qi and Yang and kidney-replenishing is as ministerial drug, it is possible to combines Radix Angelicae Sinensis and plays effect of qi and blood tonifying, with
Semen Vaccariae and Rhizoma Chuanxiong are as adjuvant drug, and for dredge the meridian passage and blood-activating and qi-promoting, Radix Glycyrrhizae Preparata plays effect of spleen reinforcing stomach function regulating, adjusts simultaneously
Save the most each all medicines, make compatibility of drugs more scientific, reasonable.
(2) tentatively pulverize and micronizing after Radix Angelicae Sinensis and Herba Leonuri being mixed, can effectively solve powder independent to Radix Angelicae Sinensis
That causes because its sugar content is higher during broken or micronizing sticks to pulverizer inwall, thus causes the problem yielded poorly, with
Time also efficiently solve because of pulverize time temperature too high reduction effective ingredient activity a difficult problem.
(3) by micronizing, the cell wall sporoderm-broken rate of medicine reaches more than 95% so that effective ingredient release is more abundant, with
Time amass increase 10 ~ 15 times compared with without the medical surfaces of micronizing so that drug use amount reduce by 50%.
(4) after using product of the present invention, the speed of growth of piglet can be accelerated, and promote its phenomenon of oestrusing, reduce puerperal and combine
Close the generation of unfavorable symptom.
(5) low cost of the present invention, preparation process is simple, and the product prepared has no side effect.
Detailed description of the invention
Embodiment 1
A kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the component of following weight portion: Herba Leonuri 40 parts,
Radix Angelicae Sinensis 40 parts, the Radix Astragali 20 parts, Herba Epimedii 20 parts, Semen Vaccariae 10 parts, Rhizoma Chuanxiong 10 parts and Radix Glycyrrhizae Preparata 5 parts.
The preparation method of the superfine powder Chinese veterinary medicinal composition of above-mentioned promotion sow postpartum recovery, comprises the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 20 mesh, is crushed to 80 mesh the most again,
Residual components is crushed to respectively 20 mesh again, is crushed to 80 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
Embodiment 2
A kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the component of following weight portion: Herba Leonuri 60 parts,
Radix Angelicae Sinensis 60 parts, the Radix Astragali 30 parts, Herba Epimedii 25 parts, Semen Vaccariae 15 parts, Rhizoma Chuanxiong 15 parts and Radix Glycyrrhizae Preparata 10 parts.
The preparation method of the superfine powder Chinese veterinary medicinal composition of above-mentioned promotion sow postpartum recovery, comprises the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 30 mesh, is crushed to 100 mesh the most again,
Residual components is crushed to respectively 30 mesh again, is crushed to 100 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
Embodiment 3
A kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the component of following weight portion: Herba Leonuri 45 parts,
Radix Angelicae Sinensis 45 parts, the Radix Astragali 22 parts, Herba Epimedii 21 parts, Semen Vaccariae 12 parts, Rhizoma Chuanxiong 12 parts and Radix Glycyrrhizae Preparata 6 parts.
The preparation method of the superfine powder Chinese veterinary medicinal composition of above-mentioned promotion sow postpartum recovery, comprises the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 25 mesh, is crushed to 90 mesh the most again,
Residual components is crushed to respectively 25 mesh again, is crushed to 90 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
Embodiment 4
A kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the component of following weight portion: Herba Leonuri 58 parts,
Radix Angelicae Sinensis 58 parts, the Radix Astragali 30 parts, Herba Epimedii 24 parts, Semen Vaccariae 15 parts, Rhizoma Chuanxiong 15 parts and Radix Glycyrrhizae Preparata 8 parts.
The preparation method of the superfine powder Chinese veterinary medicinal composition of above-mentioned promotion sow postpartum recovery, comprises the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 28 mesh, is crushed to 100 mesh the most again,
Residual components is crushed to respectively 28 mesh again, is crushed to 100 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
Embodiment 5
A kind of superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, including the component of following weight portion: Herba Leonuri 56 parts,
Radix Angelicae Sinensis 55 parts, the Radix Astragali 26 parts, Herba Epimedii 23 parts, Semen Vaccariae 13 parts, Rhizoma Chuanxiong 13 parts and Radix Glycyrrhizae Preparata 8 parts.
The preparation method of the superfine powder Chinese veterinary medicinal composition of above-mentioned promotion sow postpartum recovery, comprises the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 24 mesh, is crushed to 80 mesh the most again,
Residual components is crushed to respectively 24 mesh again, is crushed to 80 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
Experimental example 1
Experimental subject: pig farm 1
Experimentation: the farrowing sow in pig farm 1 is randomly divided into 6 deciles, and wherein 1 group is matched group, remaining 5 groups is experiment
Group, matched group uses normal feedstuff (suckling material), and based on experimental group, feedstuff (suckling material) mixes product of the present invention, the same day in puerperal
Use, it is ensured that experimental group every farrowing sow searches for food 50g product of the present invention every day, and experimental group numbering is numbered relative with embodiment
Should, use continuously and stop using after product of the present invention for 7 days, only use normal feedstuff (suckling material) until wean (26 days puerperal broke
Milk), piglet weight, 7 days wean rates of sow and inflammation rate in puerperal when period statistics newborn piglet weight, wean.
Experimental result: Oestrus rate after piglet weight (counterpoise), sow are weaned 7 days when newborn piglet weight (counterpoise), wean
1 is the results are shown in Table with inflammation rate in puerperal:
The each embodiment result in table 1 pig farm 1
| Newborn piglet weight (kg) | Piglet weight (kg) during wean | Sow is weaned Oestrus rate (%) after 7 days | Inflammation rate in puerperal (%) | |
| Matched group | 1.55 | 5.72 | 45.6 | 27.3 |
| Embodiment 1 | 1.53 | 6.31 | 86.6 | 12.0 |
| Embodiment 2 | 1.49 | 6.38 | 87.2 | 11.1 |
| Embodiment 3 | 1.51 | 6.45 | 88.3 | 10.6 |
| Embodiment 4 | 1.54 | 6.51 | 89.1 | 9.9 |
| Embodiment 5 | 1.56 | 6.59 | 90.9 | 9.1 |
Experimental example 2
Experimental subject: pig farm 2
Experimentation: the farrowing sow in pig farm 2 is randomly divided into 6 deciles, and wherein 1 group is matched group, remaining 5 groups is experiment
Group, matched group uses normal feedstuff (suckling material), and based on experimental group, feedstuff (suckling material) mixes product of the present invention, the same day in puerperal
Use, it is ensured that experimental group every farrowing sow searches for food 50g product of the present invention every day, and experimental group numbering is numbered relative with embodiment
Should, use continuously and stop using after product of the present invention for 7 days, only use normal feedstuff (suckling material) until wean (21 days puerperal broke
Milk), piglet weight, 7 days wean rates of sow and inflammation rate in puerperal when period statistics newborn piglet weight, wean.
Experimental result: Oestrus rate after piglet weight (counterpoise), sow are weaned 7 days when newborn piglet weight (counterpoise), wean
1 is the results are shown in Table with inflammation rate in puerperal:
The each embodiment result in table 1 pig farm 2
| Newborn piglet weight (kg) | Piglet weight (kg) during wean | Sow is weaned Oestrus rate (%) after 7 days | Inflammation rate in puerperal (%) | |
| Matched group | 1.54 | 5.69 | 45.3 | 27.6 |
| Embodiment 1 | 1.55 | 5.89 | 86.1 | 11.8 |
| Embodiment 2 | 1.51 | 5.94 | 87.3 | 11.2 |
| Embodiment 3 | 1.56 | 6.02 | 88.0 | 10.3 |
| Embodiment 4 | 1.48 | 6.07 | 89.1 | 9.7 |
| Embodiment 5 | 1.53 | 6.12 | 90.5 | 9.2 |
Normal feedstuff used by experimental example 1 and experimental example 2 is conventional suckling material after sow produces, when kind is varied from (still falling within
Conventional suckling material), but piglet weight, Oestrus rate and inflammation in puerperal are without significant change.
From Tables 1 and 2, after using product of the present invention, the speed of growth of piglet can be accelerated, and it is existing to promote that it is oestrused
As, reduce the generation of comprehensive unfavorable symptom in puerperal.
Claims (5)
1. the superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery, it is characterised in that include the group of following weight portion
Point: Herba Leonuri 40-60 part, Radix Angelicae Sinensis 40-60 part, Radix Astragali 20-30 part, Herba Epimedii 20-25 part, Semen Vaccariae 10-15 part, Rhizoma Chuanxiong
10-15 part and Radix Glycyrrhizae Preparata 5-10 part.
The superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery the most according to claim 1, it is characterised in that include
The component of following weight portion: Herba Leonuri 45-58 part, Radix Angelicae Sinensis 45-58 part, Radix Astragali 22-30 part, Herba Epimedii 21-24 part, Semen Vaccariae
12-15 part, Rhizoma Chuanxiong 12-15 part and Radix Glycyrrhizae Preparata 6-8 part.
The superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery the most according to claim 2, it is characterised in that include
The component of following weight portion: Herba Leonuri 56 parts, Radix Angelicae Sinensis 55 parts, the Radix Astragali 26 parts, Herba Epimedii 23 parts, Semen Vaccariae 13 parts, Rhizoma Chuanxiong 13
Part and Radix Glycyrrhizae Preparata 8 parts.
4. the preparation side of the superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery as described in any one of claim 1-3
Method, it is characterised in that comprise the following steps:
(1) weigh each composition respectively by formula, Radix Angelicae Sinensis and Herba Leonuri mix and be crushed to 20-30 mesh, is crushed to 80-the most again
100 mesh, then residual components is crushed to respectively 20-30 mesh, it is crushed to 80-100 mesh the most again, obtains raw material of Chinese medicine coarse powder；
(2) Radix Angelicae Sinensis and the Herba Leonuri coarse powder of step (1) gained are carried out micronizing, until particle diameter is less than 10 μm；
(3) other coarse powder in addition to Radix Angelicae Sinensis and Herba Leonuri coarse powder in step (1) are carried out micronizing, respectively until particle diameter is little
In 10 μm；
(4) step (2) gained material is mixed homogeneously with step (3) gained material, the superfine powder of sow postpartum recovery must be promoted
Chinese veterinary medicinal composition.
The preparation method of the superfine powder Chinese veterinary medicinal composition promoting sow postpartum recovery the most according to claim 4, it is special
Levy and be, step (1) is first crushed to 24 mesh, is crushed to 80 mesh the most again.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109247444A (en) * | 2018-11-26 | 2019-01-22 | 山西大禹生物工程股份有限公司 | A kind of feed addictive and preparation method thereof conducive to sow Recovery |
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