CN109329617A - A kind of feed addictive and its application method preventing cow postpartum retention of afterbirth - Google Patents
A kind of feed addictive and its application method preventing cow postpartum retention of afterbirth Download PDFInfo
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- CN109329617A CN109329617A CN201811364099.8A CN201811364099A CN109329617A CN 109329617 A CN109329617 A CN 109329617A CN 201811364099 A CN201811364099 A CN 201811364099A CN 109329617 A CN109329617 A CN 109329617A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
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Abstract
The invention discloses a kind of feed addictives for preventing cow postpartum retention of afterbirth.It is made of natural astaxanthin, yeast chromium, yeast selenium, vitamin E, sodium butyrate and Chinese herb feed additive (folium artemisiae argyi, Radix Astragali, Rhizoma Atractylodis Macrocephalae and cordate houttuynia).Perinatal period cow reproductive hormone secretion balance is adjusted in the feed addictive, alleviate oxidative stress and oxidative damage that perinatal period cow is subjected to, maintain the normal contractility of uterine smooth muscle, improve immunity of organisms, to accomplish to prevent the generation of cow retention of afterbirth, the recovery of cow postpartum body condition is also helped, the purpose of reproductive performance and the general level of the health is improved.
Description
Technical field
The present invention relates to a kind of feed addictives and its application method for preventing cow postpartum retention of afterbirth, belong to feed skill
Art field.
Background technique
Retention of afterbirth typically refers to 12 hours postpartum afterbirth and is not yet discharged and is trapped in intrauterine, is cow postpartum common disease
One of disease.With the continuous development of large-scale cultivation, which is showed an increasing trend year by year, and average attack rate is in 10-
25% or so, but the cattle farm having may be up to 50% or so.Retention of afterbirth is very serious to the harm of cow, does not only result in production
Afterwards heat delay, for the first time conception rate reduce and the output of milk decline, also easily secondary postpartum disease, as endometritis,
Involution of uterus delay and Uterine Prolapse etc..In production, the cow of many retentions of afterbirth is eliminated because of infertility, economic loss
It is almost the same with severe infection disease.Therefore, cow retention of afterbirth is the problem for seriously affecting cattle-raising sound development for a long time.
The cause of disease for causing retention of afterbirth is extremely complex, and single factors determine by no means, and generally acknowledged at present mainly has three aspects
The cause of disease: (1) feed is single during gestation, lacks inorganic salts, microelement and certain vitamins etc., causes calver weak, thin,
Cause postpartum uterine myometrium powerless or shrink to inhibit, afterbirth is given birth to difficulty；(2) uterus is sent out by cause pathogeny imcrobe infection
Raw endometritis, placenta inflammation, are not readily separated placentogenesis adhesion；(3) calver body inner estrogen hyposecretion, progesterone
Content is high, upsets placenta and loosens function, causes retention of afterbirth.In addition, the fortuitous events such as miscarriage and premature labor also can cause afterbirth not
Under.Treatment cow retention of afterbirth mainly increases uterine contraction ability by oxytocin injection at present, promotes afterbirth discharge, and combine
Injecting large dosage of antibiotic prevents uterine infection, manually separates mother and sons' placenta one by one using afterbirth decollement when necessary.Although this
A little treatment methods achieve certain effect, but there are the problem of be also obvious: (1) when oxytocin injection will be held
Machine is injected when cervical orifice opens a business not contracted locking, is conducive to afterbirth discharge, otherwise afterbirth can not still be discharged in intrauterine；
(2) injection of antibiotics causes the milk of production that cannot eat, and needs certain withdrawal time after curing；(3) peeling operation tire
Clothing is high to operator's technical requirements, if disinfection is not stringent, operation is rough will cause trouble instead, can also cause to produce when serious
Septicemia afterwards.Therefore, how effectively to prevent cow retention of afterbirth and have become current cattle-raising major issue urgently to be resolved.
Summary of the invention
The problem of the present invention overcomes above-mentioned productions provides a kind of feed for preventing cow postpartum retention of afterbirth
Additive.Perinatal period cow reproductive hormone secretion balance is adjusted in the feed addictive, alleviates the oxidation that perinatal period cow is subjected to
Stress and oxidative damage, maintain the normal contractility of uterine smooth muscle, improve immunity of organisms, thus accomplish prevent cow tire
Clothing not under generation.
The technical scheme is that a kind of feed addictive for preventing cow postpartum retention of afterbirth, characterized in that under
The group for stating weight percent is grouped as: natural astaxanthin 12-18%, yeast chromium 14-16%, yeast selenium 14-16%, vitamin E
20-24%, sodium butyrate 16-20% and Chinese herb feed additive 13-17%.Above-mentioned raw materials are the dry powder that granularity is less than 0.5mm.
The component and its parts by weight of said herbal medicine additive are as follows: folium artemisiae argyi 35-40, Radix Astragali 15-20, Rhizoma Atractylodis Macrocephalae 15-20, fish raw meat
Careless 25-30 is ground into the dry powder of 40-200 mesh after mixing.
Feed addictive optimum ratio (weight ratio): natural astaxanthin 15%, yeast chromium 15%, yeast selenium 15%, dimension life
Plain E 22%, sodium butyrate 18% and Chinese herb feed additive 15%.
Wherein above-mentioned raw materials natural astaxanthin, yeast chromium, yeast selenium etc. are feed grade.Natural shrimp used in the present invention
Blueness is known as effective component content >=5%.
Application method: after each component is mixed, being added directly into mixed concentrate, and additive amount is 0.8-1.5% (with mixing
Fine fodder meter)；Feeding period is to terminate 30 days to 30 days after childbirth before the cow in calf expected date of childbirth.
Each raw material effect:
Natural astaxanthin: i.e. 3,3 '-dihydroxy -4,4 '-diketo-β, β '-carrotene belong to keto-acid carotenoid,
Containing unsaturated ketone group and hydroxyl in molecular structure, free radical can be attracted or provide electronics to free radical by constituting alpha-alcohol ketone,
It is one of presently found most strong, most efficient natural, can effectively clear the oxygen radical in body cell, maintain
The normal physiological status of body.
Yeast chromium: chromium is one of microelement necessary to animal, can be improved the utilization rate of animal feed, strengthen immunity,
Improve body to undesirable condition with stress resistance, improve reproductive performance.Yeast chromium absorptivity is high, and bioactivity is good, performance
It is more stable, it is a kind of safe and efficient chromium replenishers.
Yeast selenium: selenium is growth of animal metabolism and the required microelement of breeding, resisting stress anti-oxidant to body, raising
Immunity etc. plays an important role.Yeast selenium belongs to good organic selenium source, is easily absorbed by organisms, and environmental pollution is small, has
Higher biological safety.
Vitamin E: vitamin E and selenium have synergistic function in terms of very much, including cooperate with anti-oxidant, resisting stress,
Immunity of organisms and premunition are improved, enhancing development improves reproductive performance etc..
Sodium butyrate: promote Intestinal Mucosal Immunity cell Proliferation, strengthen immunity；Improve the calcium uptake ability of cow, enhancing
The contractility of uterine smooth muscle reduces difficult labour, promotes afterbirth discharge.
Chinese herb feed additive: by folium artemisiae argyi, Radix Astragali, Rhizoma Atractylodis Macrocephalae and cordate houttuynia prescription, wherein folium artemisiae argyi warming channel for arresting bleeding is monarch drug in a prescription；Radix Astragali
Tonifying Qi and lifting yang, shengjin nourishing are ministerial drug；Rhizoma Atractylodis Macrocephalae strengthening the spleen and replenishing qi, miscarriage prevention, eliminate dampness and have diuretic effect, cordate houttuynia is clearing heat and detoxicating, and inducing diuresis for treating strangurtia is
Adjuvant.Above-mentioned raw materials collective effect has the function of recuperating qi-blood, strengthening spleen, tonifying kidney, temperature through miscarriage prevention, and the machine of cow can be enhanced
Body immunity function, also has antagonism and lethal effect to various bacteria and virus, and also liver protection diuresis improves resisting stress capability
Effect.
Beneficial effects of the present invention: above-mentioned several raw materials are carried out prescription by the present invention, and wherein natural astaxanthin has relatively strong
Oxidation resistance it is strong, yeast chromium, yeast selenium, vitamin E and Chinese herb feed additive supplement body vitamin, microelement and
Improve the immune of body, resisting stress and antibacterial, antiviral, contractility of the sodium butyrate with enhancing uterine smooth muscle, promotion tire
The effect that clothing discharge and enhancing are immunized.Each raw material collective effect, is adjusted perinatal period cow reproductive hormone secretion balance, and alleviation is enclosed
The oxidative stress and oxidative damage that term cow is subjected to maintain the normal contractility of uterine smooth muscle, improve immunity of organisms,
To accomplish to prevent the generation of cow retention of afterbirth, it is conducive to cow postpartum body condition and restores, improve reproductive performance and the general level of the health
Purpose.Also improve antibacterial, anti-virus ability, the antibiotic in alternative daily ration.
Specific embodiment
In the present embodiment, the manufacturer of natural astaxanthin is Yunnan Ai Erfa astaxanthin biological Technology Co., Ltd., is had
Effective component content is 5%.The manufacturer of yeast chromium be Angel Yeast Co., Ltd, content 99%, chromium content be >=
0.2%.The manufacturer of yeast selenium is Angel Yeast Co., Ltd, and Se content is >=0.2%.
Embodiment 1:
It matches (weight ratio): natural astaxanthin 15%, yeast chromium 15%, yeast selenium 15%, vitamin E 22%, sodium butyrate
18% and Chinese herb feed additive 15%.Above-mentioned raw materials granularity is the dry powder less than 0.5mm.
Chinese herb feed additive (parts by weight): folium artemisiae argyi 35, Radix Astragali 15, Rhizoma Atractylodis Macrocephalae 15, cordate houttuynia 25 are ground into 100 mesh after mixing
Dry powder.
Experimental design:
According to cow age, parity, physical condition and the expected date of childbirth close principle, select 60 sharp wood praise × western Shandong Huang is miscellaneous
Cow is handed over, carries out feeding experiment at the Jinan City town Tang Wang " Li Luniu core breeding station " in the 10-12 month in 2017.Participate in test
Cow is randomly divided into control group and test group, is respectively 30.Control group fed cow in calf mixed concentrate (academy of agricultural sciences of Shandong Province poultry
Herd the production of centre of development feed factory), test group adds the feed addictive that 1.5% present invention prepares in mixed concentrate.Feeding
Period is to terminate 30 days to postpartum 30 days before the cow in calf expected date of childbirth, experimental period 60 days.Cow list slot bolt during test
System's raising, every morning 7:00 and 18:00 in afternoon are respectively fed 1 time, first thick after essence, free water.Observe cow postpartum afterbirth not
Under incidence and pregnancy rate in 90 days, with evaluate feed addictive of the invention to cow postpartum afterbirth discharge and reproductive performance
The influence of recovery；On-test, childbirth the 1st day and at the end of vena cava anterior take a blood sample, detect serum in progesterone and estradiol content,
To evaluate the influence of feed addictive of the invention to perinatal period cow levels of reproductive hormones；Vena cava anterior is adopted when off-test
Blood detects sero-immunity index, to evaluate the influence of feed addictive of the invention to cow postpartum immune function.As a result such as table
Shown in 1-4.
The observation result of 1 cow postpartum Major Clinical index of table
Note: same column shoulder mark lowercase difference person, significant difference (p < 0.05), similarly hereinafter.
Influence (pg/mL) of 2 compound additive of table to cow progesterone level
| Group | Gestation 255 days | It gives a birth the 1st day | 30 days after childbirth |
| Control group | 418.3±23.8a | 137.6±12.4a | 206.8±9.6a |
| Test group | 409.2±16.4a | 103.1±7.1b | 202.3±10.4a |
Influence (pg/mL) of 3 compound additive of table to cow estradiol level
| Group | Gestation 255 days | It gives a birth the 1st day | 30 days after childbirth |
| Control group | 7.98±0.58a | 9.06±0.22b | 6.82±0.28a |
| Test group | 8.63±0.49a | 11.65±0.49a | 6.50±0.17a |
Influence (g/L) of 4 compound additive of table to cow postpartum immune function
| Group | IgA | IgG | IgM | Complement C_3 | Complement C4 |
| Control group | 0.55±0.01 | 1.59±0.01 | 0.22±0.01 | 0.09±0.0 | 0.07±0.0 |
| Test group | 0.69±0.01 | 1.77±0.1 | 0.30±0.01 | 0.12±0.01 | 0.09±0.0 |
The result shows that cow postpartum retention of afterbirth can not only effectively be prevented by adding 1.5% compound additive in mixed concentrate
Restore with promotion postpartum reproductive performance, and improves perinatal period cow entirety immune level.Seen from table 1, test group mixing essence
1.5% compound additive is added in material, afterbirth discharge rate is 100% after cow childbirth, significantly improves 16.7% compared with control group；It produces
Pregnancy rate is 93.3% in 90 days afterwards, significantly improves 26.6% compared with control group.By table 2,3 as it can be seen that adding in test group mixed concentrate
Add 1.5% compound additive, progesterone content is substantially less than control group when childbirth, and estradiol content is significantly higher than control group, this has
It plays a role conducive to the two collaboration, improves endometrium to the sensibility of oxytocins, stimulate uterine contraction, afterbirth is discharged.By table 4
As it can be seen that adding 1.5% compound additive in mixed concentrate, cow postpartum entirety immune level is significantly improved, compared with the control group,
25.5%, 11.3%, 36.4%, 33.3% and is respectively increased in IgA, IgG, IgM, Complement C_3 in blood, Complement C4 level
28.6%.
It can be seen that natural astaxanthin, yeast chromium, yeast selenium, vitamin E, sodium butyrate and Chinese herb feed additive are matched
5, respective advantage can not only be given full play to, and there is synergistic effect, the discharge of cow postpartum afterbirth and reproductive performance are restored
The effect of being significantly improved, cow postpartum entirety immune level significantly improve.
Embodiment 2
It matches (weight ratio): natural astaxanthin 18%, yeast chromium 15%, yeast selenium 15%, vitamin E 24%, sodium butyrate
16% and Chinese herb feed additive 12%.Above-mentioned raw materials granularity is the dry powder less than 0.5mm.
Chinese herb feed additive (parts by weight): folium artemisiae argyi 40, Radix Astragali 20, Rhizoma Atractylodis Macrocephalae 20, cordate houttuynia 30 are ground into 200 mesh after mixing
Dry powder.
Application method: after each component is mixed, being added directly into mixed concentrate, and additive amount is 0.8-1.5% (with mixing
Fine fodder meter)；Feeding period is to terminate 30 days to 30 days after childbirth before the cow in calf expected date of childbirth.
Embodiment 3
It matches (weight ratio): natural astaxanthin 14%, yeast chromium 14%, yeast selenium 16%, vitamin E 22%, sodium butyrate
20% and Chinese herb feed additive 14%.Above-mentioned raw materials granularity is the dry powder less than 0.5mm.
Chinese herb feed additive (parts by weight): folium artemisiae argyi 38, Radix Astragali 17, Rhizoma Atractylodis Macrocephalae 17, cordate houttuynia 28 are ground into 100 mesh after mixing
Dry powder.
Application method: after each component is mixed, being added directly into mixed concentrate, and additive amount is 0.8-1.5% (with mixing
Fine fodder meter)；Feeding period is to terminate 30 days to 30 days after childbirth before the cow in calf expected date of childbirth.
Claims (5)
1. a kind of feed addictive for preventing cow postpartum retention of afterbirth, characterized in that be grouped by the group of following weight percentage
At: natural astaxanthin 12-18%, yeast chromium 14-16%, yeast selenium 14-16%, vitamin E 20-24%, sodium butyrate 16-
20% and Chinese herb feed additive 13-17%；
The component and its parts by weight of the Chinese herb feed additive are as follows: folium artemisiae argyi 35-40, Radix Astragali 15-20, Rhizoma Atractylodis Macrocephalae 15-20, cordate houttuynia
25-30。
2. a kind of feed addictive for preventing cow postpartum retention of afterbirth as described in claim 1, characterized in that the medium-height grass
The dry powder of 40-200 mesh is ground into after each component mixing of medicine additive.
3. a kind of feed addictive for preventing cow postpartum retention of afterbirth as described in claim 1, characterized in that described natural
Astaxanthin, yeast chromium, yeast selenium, vitamin E and sodium butyrate are the dry powder that granularity is less than 0.5mm.
4. a kind of feed addictive for preventing cow postpartum retention of afterbirth as described in claim 1, characterized in that the feed
Additive is grouped as by the group of following weight percentage: natural astaxanthin 15%, yeast chromium 15%, yeast selenium 15%, vitamin E
22%, sodium butyrate 18% and Chinese herb feed additive 15%.
5. a kind of feed addictive for preventing cow postpartum retention of afterbirth as described in any one of claim 1-4, special
Sign is after mixing each component of feed addictive, to be added directly into mixed concentrate, additive amount 0.8-1.5%；When feeding
Phase is to terminate 30 days to 30 days after childbirth before the cow in calf expected date of childbirth.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109874931A (en) * | 2019-04-22 | 2019-06-14 | 威海金牌生物科技股份有限公司 | A kind of mixed feed and preparation method thereof improving Bao high-temperature resistance |
| CN110140816A (en) * | 2019-07-03 | 2019-08-20 | 济南阔达生物科技有限公司 | A kind of feed addictive preventing ewe endometritis and its application method |
| CN114128798A (en) * | 2021-12-06 | 2022-03-04 | 吉林大学 | Feed additive for improving cow mating rate and preparation method thereof |
| CN115918793A (en) * | 2022-12-22 | 2023-04-07 | 吉林大学 | Feed additive for improving disease resistance and productivity of dairy cows and preparation method thereof |
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