JP2001211781A - Method for preventing reproduction disorder of cow and feed composition used for the above method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a method for preventing a reproduction disorder of cows, since in recent years, a conception by one time artificial insemination becomes less in a highly secreting milking cow fed with a concentrated feed and it becomes an important problem to improve the conception rate by reducing the period from delivery to conception, i.e., to prevent the reproduction disorder, and a feed composition used for the above method. SOLUTION: This method for preventing the reproduction disorder of cows is to feed astaxanthin to cows after delivery. It is preferable to feed astaxanthin which is rumen bypass-treated by covering it with a fatty acid salt, by 10-200 mg as a daily dose.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a method for preventing reproductive disorders in cattle and a feed composition used for the method.

[0002]

BACKGROUND OF THE INVENTION The lactation period of dairy cows is about 9 to 10 months, and the milk yield gradually decreases, with the maximum about 60 days after parturition. At this time, artificial insemination is performed for the next delivery. When about 300 days have passed since the delivery, the milk yield is reduced to 1/3 of the maximum, so milking is stopped until the next delivery. If this dry period can be shortened, the lactation period will be relatively long and the production cost of milk will be low. However, in recent years, fertilization of high-dairy cows that have been fed a high concentration of feed has been less likely to be conception by one artificial insemination, and the conception rate has been improved to shorten the period from calving to the next conception, that is, to prevent reproductive disorders. Is an important issue in dairy management.

[0003] Also, in the case of beef cattle, the conception rate has decreased as in the case of dairy cows. In the case of beef cattle, especially since the cost of artificial insemination (seed fee) is expensive, the advantage of conception with one artificial insemination is great, and prevention of reproductive disorders is an important management issue as in the case of dairy cows. Has become.

[0004]

2. Description of the Related Art The causes of reproductive disorders are mainly luteal dysfunction and ovarian cysts (luteal cysts and follicular cysts), and the symptoms are arousal and persistent estrus. When these symptoms are observed, vitamin preparations, hormonal preparations, amino acids (Japanese Unexamined Patent Publication No.
No. 631), uterine washing, intrauterine drug solution injection, etc., are not always effective, and many cows are discarded. Currently, about 25% of dairy cow abandonment causes reproductive disorders. As a preventive method, a thick feed is restricted, that is, a low protein feed is fed. However, this method has a disadvantage that a milk amount is reduced.

On the other hand, astaxanthin is a carotenoid pigment, and is widely distributed in nature in green algae such as haematococcus, crustaceans such as phafia yeast, shrimp and krill, fish and birds. It is mainly used for improving the color tone of fish such as red sea bream, but there is no report that it was used to prevent cattle disease.

[0006]

SUMMARY OF THE INVENTION The present invention provides a method for preventing reproductive disorders in cattle and a feed composition used for the method.

[0007]

Means for Solving the Problems In order to solve the above-mentioned problems, the present inventors have searched for useful substances for preventing reproductive disorders in cattle, and found that astaxanthin used for improving the color tone of red sea bream and the like is used. (Hereinafter sometimes referred to as AX) was found to significantly shorten the period from delivery to the next conception, and thus completed the present invention.

[0008] That is, the present invention provides a method for preventing reproductive disorders in cattle, characterized by feeding astaxanthin. The present invention also provides an astaxanthin-containing feed composition for preventing reproductive disorders in cattle, which is used in the method. In this specification, prevention of reproductive disorders in cattle means shortening the period from calving to the next conception.

The astaxanthin used in the present invention comprises:
Both natural products and synthetic products can be used. Astaxanthin-containing natural products such as shrimp shell, crab shell, krill, prawns, Phaffia yeast, hematococcus and the like can be used as a natural product itself, but these are previously pulverized or oiled, extracted with an organic solvent, etc. to extract astaxanthin. Those with improved utilization are preferred. For example, in the case of Phaffia yeast, those obtained by previously pulverizing the yeast cell wall using a roll mill, a ball mill, a jet mill, or the like can be suitably used. (Japanese Unexamined Patent Publication Nos. Hei 6-319531 and Hei 8-182).

[0010] Furthermore, if these astaxanthin-containing substances are used after being subjected to rumen bypass treatment, the objective can be achieved with a smaller amount of administration, which is economically preferable. Generally, when a biologically active substance is orally administered to ruminants such as cattle, it is stable in the rumen gastric juice and prevents the abomasum and beyond, in order to prevent decomposition by microorganisms present in the rumen of ruminants. There is a lumen bypass treatment that coats the active substance with a substance that disintegrates in the digestive tract. In the present invention, any of the known rumen bypass treatments can be used, but divalent metal salts of fatty acids such as stearic acid, linoleic acid, and oleic acid (for example, magnesium salt, calcium salt) (Salt). In addition, among these fatty acid salts, magnesium salts and calcium salts of unsaturated fatty acids such as linoleic acid and oleic acid have an effect of enhancing the effect of preventing astaxanthin's reproductive disorders even if they are used in combination without being coated with astaxanthin. Is most preferred.

The present invention is applicable to dairy cows such as Holstein breeds and jersey breeds, and beef cattle such as Japanese black breeds. Astaxanthin is fed to cattle at least 20 days before estrus in accordance with the estrous cycle, preferably immediately after parturition, in the form of oral administration and continued until conception is confirmed. Feeding to cattle can be performed by suspending the above-mentioned astaxanthin-containing substance in water or the like and forcibly administering it. However, since the palatability is not bad, it is preferable from the viewpoint of working efficiency to mix and freely ingest the compound feed. .

When the amount of astaxanthin administered is 5 mg or more per day in the case of rumen bypass treatment, the conception rate of cattle is improved, and there is an excellent effect of preventing reproductive disorders. Although there is no particular upper limit, a daily supply of 5 to 200 mg is preferable from an economic viewpoint. In addition, when astaxanthin that has not been subjected to rumen bypass treatment is fed alone, the same effect can be obtained by feeding 100 mg or more as a daily dose.

When astaxanthin has not been subjected to rumen bypass treatment, unsaturated fatty acids or salts thereof may be replaced with 1
25 g to 500 g, preferably 50 g to 20 per day
When 0 g is used in combination, the same effect of preventing reproductive disorders can be obtained by feeding a smaller amount of astaxanthin, that is, 15 mg or more as a daily dose. As unsaturated fatty acids or salts thereof that can be used, unsaturated fatty acids such as oleic acid, linoleic acid, linolenic acid, eicosapentaenoic acid, docosahexaenoic acid or a mixture of two or more thereof, or divalent metal salts thereof (magnesium salts, Calcium salts), but divalent metal salts are preferred because they bypass the lumen. If the amount of the unsaturated fatty acid salt is within the above range, a saturated fatty acid salt such as a stearic acid salt may be mixed.

The method of the present invention can effectively prevent the reproductive dysfunction of cattle only by feeding astaxanthin, which also exists in nature and whose safety has been confirmed. In addition, there is no disadvantage that the amount of milk is reduced in application to dairy cows, and the present invention greatly contributes to management for cattle breeding farmers.

[0015]

The present invention will be described in more detail with reference to the following Examples, which do not limit the scope of the present invention.

Example 1 750 g of Phaffia yeast (5000 ppm of AX content) previously ground by a jet stream mill (jet mill).
Was mixed with 600 ml of linoleic acid and kneaded with a biaxial kneader, and 150 g of slaked lime was gradually added and mixed. This was crushed and sized using a high-speed hammer mill (manufactured by Hosokawa Micron Corporation) at 9600 rpm,
1 kg of a rumen-bypassed AX-containing feed composition (AX content: 3,000 ppm, particle size: 9 mesh) was produced.

EXAMPLE 2 Ten Holstein cows (two cows) were used in the test. About 5 of them, Example 1 immediately after delivery
Of the AX-containing feed composition as AX was 15 mg / head /
On the day, it was mixed with the compound feed and fed daily, and artificial insemination was performed (AX-fed section). The remaining five animals were subjected to artificial insemination without feeding the AX-containing feed composition (the AX non-fed group). Artificial insemination was performed when estrus occurred 50 days after delivery and repeated until conception. Table 1 shows the results.
Note that the number of days until conception in Table 1 indicates the number of days from the date of delivery to the day of artificial insemination at which the veterinarian has confirmed conception. As is clear from Table 1, when AX was fed, the period until conception was shortened, and reproductive disorders were prevented. Regarding milk production, AX salary and AX
There was no apparent difference from the unpaid district.

[0018]

[Table 1] ――――――――――――――――――――――――― Test area Test cattle Days until conception ――――――――――― ―――――――――――――――― AX Salary Ward No.1 105 days No.2 92 days No.3 85 days No.4 102 days No.5 62 days ―――――― ――――――――――――――――――――― Average of No.1 to No.5 89.2 days ―――――――――――――――― ――――――――――― AX unpaid ward No.6 165 days No.7 138 days No.8 101 days No.9 145 days No.10 126 days ―――――――――― ――――――――――――――――― Average of No.6 to No.10 135.0 days ―――――――――――――――――――― ―――――――

Example 3 In the tests, Holstein cows (two to three cows) were used.
The head was used. Among them, 10 animals were divided into 5 groups of 2 animals, and immediately after parturition, the AX-containing feed composition of Example 1 was used as AX at 10, 20, 50, 100, and 2 respectively.
The mixture was fed to a compound feed at 00 mg / head / day and fed daily to perform artificial insemination (AX fed group). The remaining four animals were subjected to artificial insemination without feeding the AX-containing feed composition (AX
Unpaid ward). Artificial insemination was performed in the same manner as in Example 2. Table 2 shows the results. In addition, the determination of conception in Table 2 was evaluated as ○ when the conception was confirmed within 120 days from the delivery date to the date of artificial insemination, and × when the conception was not confirmed. As is clear from Table 2, AX was 10 to 200 mg /
When fed within the head / day range, conception was confirmed early, and reproductive disorders were prevented. In addition, there was no clear difference in the milk yield between the AX-fed and non-AX-fed groups.

[0020]

[Table 2] ――――――――――――――――――――――――― Test plot AX dose Test cow conception ――――――――――― ―――――――――――――――― AX Salary Ward 10mg / head / day No.11 ○ No.12 ○ 20mg / head / day No.13 ○ No.14 ○ 50mg / head / day No.15 ○ No.16 ○ 100mg / head / day No.17 ○ No.18 ○ 200mg / head / day No.19 ○ No.20 ○ ―――――――――――――――――― ――――――――――― AX unpaid area 0mg / head / day No.21 × No.22 ○ No.23 × No.24 × ―――――――――――――― ―――――――――――――

Example 4 For about one and a half years, a Japanese black calf (2 calves, about 400 kg in weight) which did not conceive even after artificial insemination was carried out 20 days before estrus in accordance with the estrous cycle. The AX-containing feed composition of Example 1 was mixed with a mixed feed at a dose of 15 mg / head / day as AX and fed daily to perform artificial insemination. As a result, the AX-containing feed composition was fertilized at the first artificial insemination after feeding.

Example 5 The AX-containing feed composition of Example 1 was fed to a Japanese black calf (about 400 kg in weight), who had not conceived even after artificial insemination for about half a year, according to the estrous cycle, 20 days before estrus. Was fed as an AX at a dose of 15 mg / head / day in a compound feed and fed daily to perform artificial insemination. As a result, the AX-containing feed composition was fertilized at the first artificial insemination after feeding.

Claims (11)

[Claims] 1. A method for preventing reproductive disorders in cattle, which comprises feeding astaxanthin. 2. The method according to claim 1, wherein the astaxanthin to be supplied has been subjected to a rumen bypass treatment. 3. The method according to claim 1, wherein the astaxanthin to be supplied has been subjected to rumen bypass treatment by coating with fatty acid calcium. 4. A daily dose of astaxanthin of 5-2.
4. The method according to any one of claims 1 to 3, wherein the method provides a dose of 00 mg. 5. A method for preventing reproductive disorders in cattle, comprising feeding astaxanthin and an unsaturated fatty acid or a salt thereof. 6. The method according to claim 5, wherein the unsaturated fatty acid is linoleic acid. 7. A daily dosage of astaxanthin of 15 to 15%.
The method according to claim 5 or 6, wherein 200 mg is supplied. 8. A feed composition for preventing reproductive disorders in cattle, comprising astaxanthin. 9. The feed composition according to claim 8, wherein the astaxanthin is subjected to a rumen bypass treatment. 10. The feed composition according to claim 8, wherein the astaxanthin has been subjected to rumen bypass treatment by coating with fatty acid calcium. 11. A feed composition for preventing reproductive disorders in cattle, comprising astaxanthin and unsaturated fatty acids or salts thereof.