CN105497412A - Agentia for promoting oestrus and ovulation of ewes and preparing method thereof - Google Patents

Agentia for promoting oestrus and ovulation of ewes and preparing method thereof Download PDF

Info

Publication number
CN105497412A
CN105497412A CN201510937701.2A CN201510937701A CN105497412A CN 105497412 A CN105497412 A CN 105497412A CN 201510937701 A CN201510937701 A CN 201510937701A CN 105497412 A CN105497412 A CN 105497412A
Authority
CN
China
Prior art keywords
parts
ovulation
agentia
ewe
ewes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510937701.2A
Other languages
Chinese (zh)
Inventor
孙自富
刘宏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510937701.2A priority Critical patent/CN105497412A/en
Publication of CN105497412A publication Critical patent/CN105497412A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533—Leonurus (motherwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/64—Orobanchaceae (Broom-rape family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses agentia for promoting oestrus and ovulation of ewes. The agentia is prepared from radix astragali, semen cuscutae, herba epimedii, motherwort, actinolite, herba taxilli, common yam rhizome, flos carthami, radix rehmanniae preparata, cistanche, Chinese dates, radix codonopsis, glossy privet fruit and additives. The Chinese herbs are used as main raw materials and are reasonably matched according to the relation of monarch, minister, assistant and guide of traditional Chinese medicine, the different components take effect synergetically, and therefore the agentia has good aphrodisiac and ovulation-promoting functions; the additives are used and can improve the irritant taste of Chinese herb liquid, have a feed attracting effect, can provide rich microelements for the ewes, assist in recovery and stabilization of internal secretion and physiques of the ewes and enhance the use effect of the Chinese herb liquid. The agentia is liquid at normal temperature and can be doped into feed or mixed with water to be taken, and operation of using the agentia is easier than that of an existing artificial aphrodisiac method; the use effect is good, most ewes can be in heat and mated within five days after ablactation, and the fertilization success rate reaches 97% or above.

Description

A kind ofly promote that ewe oestruses the medicament and preparation method thereof of ovulation
Technical field
The present invention relates to a kind of medicament of raising ewe, be specifically related to a kind ofly promote that ewe oestruses the medicament and preparation method thereof of ovulation.
Background technology
The breeding cycle of ewe and farrowing rate are the fast development of flock of sheep and the key link of enterprise's culture benefit, the natural feeding cycle of current ewe is 3 ~ 4 months, long suckling causes ewe hormonal change larger, body constitution declines relatively, need the recovery of a period of time to take good care of after wean, and now ewe is rather responsive to growing environment condition, the fluctuation of the factors such as illumination, temperature, feedstuff all can cause ewe to postpone oestrus, breeding must be caused to postpone, affect the income of culturist.Current people are in order to promote that ewe oestruses ovulation, general use hormone is promoted the sexual maturity method, hormone method of promoting the sexual maturity is divided into again heeling-in method and intravaginal sponge method, heeling-in method: with veterinary's heeling-in rifle by appropriate hormone, such as medroxyprogesterone, megestrol, progesterone, be imbedded at the ewe basal part of the ear subcutaneous, after 10 ~ 12 days, to ewe intramuscular injection pregnant mare serum 400 ~ 750 iu, can oestrus after 2 ~ 3; Intravaginal sponge method: the sponge being soaked with progestogen is placed in ewe external os of vervix place 10 ~ 14 days, injects pregnant mare serum 400 ~ 500 iu, can oestrus through about 30h after drug withdrawal.Can find out that the operational approach of prior art is comparatively complicated, and use external hormone to regulate, easily cause the hormonal readiness in animal body unbalance, cause endocrine disturbance, be unfavorable for sustainable development.
Summary of the invention
In order to solve the problem, the invention provides and a kind ofly promote that ewe oestruses the medicament and preparation method thereof of ovulation, made medicament can promote that ewe oestruses, shorten breeding cycle, increase farrowing quantity, increase economic efficiency, and medicament is without any side effects to ewe, be conducive to sustainable development.
The present invention is achieved through the following technical solutions:
Promote ewe oestrus ovulation a medicament, be made up of the material of following weight portion:
5 ~ 8 parts of Radixs Astragali, 5 ~ 8 parts of Semen Cuscutae, 4 ~ 6 parts of Herba Epimedii, 3 ~ 6 parts of Herba Leonuris, 4 ~ 5 parts of Actinolitum, 3 ~ 4 parts of Herba Taxillis, 2 ~ 4 parts of Rhizoma dioscoreaes, 2 ~ 4 parts of Flos Carthamis, 3 ~ 5 parts of Radix Rehmanniaes Preparata, 4 ~ 6 parts of Herba Cistanches, 2 ~ 4 portions of Fructus Jujubaes, 2 ~ 5 parts of Radix Codonopsis, 3 ~ 6 parts of Fructus Ligustri Lucidi, 1 ~ 2 part of additive.
Further, described additive is made up of the material of following weight portion: 5 ~ 10 portions of Sal, 2 ~ 3 parts of aspartames, 1 ~ 3 part of compound vitamin, 0.2 ~ 0.3 part of carbonate rare earth, 0.3 ~ 0.5 part of bacillus titanium zinc.
Further, vitamin A, vitamin D and vitamin E is contained in described compound vitamin.
Promote that ewe oestruses the preparation method of medicament of ovulation, comprises the steps:
(1) 4 ~ 5 parts of Actinolitum are put into crucible, after heating and calcining is aglow, the pure rear pulverizing of yellow wine leaching of pouring its quality 1/4 ~ 1/5 into is for subsequent use;
(2) stirring to faint yellow by putting into hot pot with Testa Tritici after 2 ~ 4 parts of Rhizoma dioscoreae cuttings, cooling for subsequent use after sieve removes wheat bran;
(3) 4 ~ 6 parts of Herba Cistanches to be put into etc. the water of its quality, after soaking 5 ~ 10min, change water at every turn, dry for subsequent use after repetitive operation 3 ~ 4 times;
(4) made for above-mentioned steps material is put into the water of its gross mass 3 ~ 5 times with residual components, after intense fire boils, then use slow fire boiling 15 ~ 20min, after filtration, filtrate is concentrated into the half of original volume.
In medicine component of the present invention, the Radix Astragali: nature and flavor are sweet, tepor, return lung, spleen channel, have tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promote the production of body fluid nourish blood, the stagnant blood stasis dispelling of row, expelling pus and toxin by strengthening QI and expelling pus and promoting granulation function, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, have blood in stool metrorrhagia, exterior deficiency spontaneous perspiration, deficiency of vital energy edema weak for the deficiency of vital energy, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, hemiplegia, arthralgia pain are numb, carbuncle difficult burst and burst for a long time do not hold back; Semen Cuscutae: the effect with nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive improving eyesight, to suffer from a deficiency of the kidney the treatment of rushing down for impotence and seminal emission, dripping urination, vaginal bleeding due to deficiency of the kidney during pregnancy, spleen; Herba Epimedii: nature and flavor acrid, sweet, warm, returns liver, kidney channel, has the function of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling, rheumatic arthralgia, numbness contracture soft for kidney yang deficiency, impotence and seminal emission, muscles and bones flaccidity; Herba Leonuri: nature and flavor are bitter, pungent, are slightly cold, return liver, pericardium, urinary bladder channel, have the function of promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing, for menoxenia, dysmenorrhea amenorrhea, lochiorrhea, edema oliguria, sore swollen toxin; Actinolitum: warm in nature salty, has effect of warming the kidney to invigorate YANG, and after yellow wine leaching is pure, effect is better; Herba Taxilli: have invigorating the liver and kidney, bone and muscle strengthening, except the antiabortive effect of rheumatism, network of promoting blood circulation, beneficial blood; Rhizoma dioscoreae sweet in the mouth, property is put down, kidney tonifying gas, strengthening the spleen and stomach, has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, helps effect of the five internal organs, bone and muscle strengthening; Flos Carthami: property is pungent, warm, enters the heart, Liver Channel, has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Radix Rehmanniae Preparata: there is YIN nourishing effect of enriching blood, diseases such as can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, pass out semen, quench one's thirst; Herba Cistanches: sweet in the mouth, salty, warm in nature, has the effect in kidney-replenishing, benefiting essence-blood, intestine moistening road, for asthenia of essence and blood, and nebulousurine, the frequent micturition heeltap, infertility, the treatment of the symptoms such as dryness of the intestine constipation; Fructus Jujubae: sweet in the mouth is warm in nature, has the function of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine; Radix Codonopsis: sweet in the mouth, property are put down, return spleen lung kidney channel, have invigorating the spleen and benefiting QI, tonifying the lung and stopping cough, enriching kidney essence, effect of stimulating milk secretion.Be used for the treatment of uterine hypoplasia, deficiency of kidney-QI, asthenia internal injury, cardiopalmus weak, insufficiency of the spleen let out wash, the disease such as leucorrhea is many, poliomyelitis, breast rareness, the enuresis, the deficiency of the lung, cough; Fructus Ligustri Lucidi: nature and flavor are bitter, cool, return liver, kidney channel, have the effect of nourishing the liver and kidney, improving eyesight black hair, for the hepatic and renal YIN deficiency, dizzy ear toot, soreness of the waist and knees, early whitening of beard and hair, poor vision, interior-heat quench one's thirst and osteopyrexia and fever.Above-mentioned Chinese medicine ingredients non-fully are simply piled up, but consider that drug effect between heterogeneity is arranged in pairs or groups with coordinating, as the Radix Astragali, Herba Epimedii and Semen Cuscutae coordinated, there is invigorating vital QI, kidney invigorating and YANG supporting, the effect of control agent internal hormone balance, Flos Carthami and Herba Leonuri coordinate the irritability that can strengthen uterus, and Fructus Ligustri Lucidi coordinates the effect can playing estrogen with Radix Codonopsis, physiological change during the similar normal oestrus such as induce vaginal mucosa to carry out a series of hyperemia, to come off.
The present invention has following beneficial effect: the present invention take Chinese herbal medicine as primary raw material, the monarch and his subjects' relation of assisting a ruler in governing a country according to Chinese medicine has carried out rational collocation, synergism between different component, make it have good Effect of Ovulation of promoting the sexual maturity, the use of additive can improve the stimulation taste of Chinese herbal medicine fluid, plays food calling effect, can provide abundant trace element again for ewe, assist the recovery of its endocrine and body constitution and stablize, enhancing the result of use of Chinese herbal medicine fluid.Be liquid under this medicament room temperature, can mix feedstuff or mix water delivery service, simple to operate many than existing artificial propagation method, and result of use is good, copulation of just can oestrusing in after wean 5 days of ewe in most puerperal, fertilization success rate reaches more than 97%.
Detailed description of the invention
Embodiment 1
Promote ewe oestrus ovulation a medicament, be made up of the material of following weight portion:
6 parts of Radixs Astragali, 5 parts of Semen Cuscutae, 6 parts of Herba Epimedii, 5 parts of Herba Leonuris, 4 parts of Actinolitum, 3 parts of Herba Taxillis, 4 parts of Rhizoma dioscoreaes, 2 parts of Flos Carthamis, 3 parts of Radix Rehmanniaes Preparata, 6 parts of Herba Cistanches, 2 portions of Fructus Jujubaes, 4 parts of Radix Codonopsis, 5 parts of Fructus Ligustri Lucidi, 2 parts of additives.
Further, described additive is made up of the material of following weight portion: 8 portions of Sal, 2 parts of aspartames, 2 parts of compound vitamines, 0.2 part of carbonate rare earth, 0.4 part of bacillus titanium zinc.
Further, vitamin A, vitamin D and vitamin E is contained in described compound vitamin.
Promote that ewe oestruses the preparation method of medicament of ovulation, comprises the steps:
(1) 4 parts of Actinolitum are put into crucible, after heating and calcining is aglow, the pure rear pulverizing of yellow wine leaching of pouring its quality 1/4 into is for subsequent use;
(2) stirring to faint yellow by putting into hot pot with Testa Tritici after 4 parts of Rhizoma dioscoreae cuttings, cooling for subsequent use after sieve removes wheat bran;
(3) 6 parts of Herba Cistanches to be put into etc. the water of its quality, each soak 8min after change water, dry for subsequent use after repetitive operation 3 times;
(4) made for above-mentioned steps material is put into the water of its gross mass 5 times with residual components, after intense fire boils, then use slow fire boiling 16min, after filtration, filtrate is concentrated into the half of original volume.
Embodiment 2
Promote ewe oestrus ovulation a medicament, be made up of the material of following weight portion:
7 parts of Radixs Astragali, 6 parts of Semen Cuscutae, 4 parts of Herba Epimedii, 5 parts of Herba Leonuris, 4 parts of Actinolitum, 3 parts of Herba Taxillis, 4 parts of Rhizoma dioscoreaes, 2 parts of Flos Carthamis, 4 parts of Radix Rehmanniaes Preparata, 5 parts of Herba Cistanches, 4 portions of Fructus Jujubaes, 3 parts of Radix Codonopsis, 5 parts of Fructus Ligustri Lucidi, 2 parts of additives.
Further, described additive is made up of the material of following weight portion: 9 portions of Sal, 2 parts of aspartames, 2 parts of compound vitamines, 0.2 part of carbonate rare earth, 0.4 part of bacillus titanium zinc.
Further, vitamin A, vitamin D and vitamin E is contained in described compound vitamin.
Promote that ewe oestruses the preparation method of medicament of ovulation, comprises the steps:
(1) 4 parts of Actinolitum are put into crucible, after heating and calcining is aglow, the pure rear pulverizing of yellow wine leaching of pouring its quality 1/5 into is for subsequent use;
(2) stirring to faint yellow by putting into hot pot with Testa Tritici after 4 parts of Rhizoma dioscoreae cuttings, cooling for subsequent use after sieve removes wheat bran;
(3) 5 parts of Herba Cistanches to be put into etc. the water of its quality, each soak 6min after change water, dry for subsequent use after repetitive operation 4 times;
(4) made for above-mentioned steps material is put into the water of its gross mass 3 times with residual components, after intense fire boils, then use slow fire boiling 15min, after filtration, filtrate is concentrated into the half of original volume.
For contrast effect of the present invention, on October 31,1 day to 2015 March in 2015, from Taihe County, Anhui Province, goat plant selects the moderate healthy multiparity she-goat 200 of the growth of livestock carefully, be divided into two groups at random, one group is experimental group 1, one group is matched group 1, carry out isolated rearing respectively, two groups are all first carried out that the short-term of month is excellent raises, April 1 rose, in the feedstuff of experimental group, mix medicament of the present invention carry out feeding, every day twice, matched group feedstuff is left intact, carry out examination feelings after three days to detect, to oestrusing, ewe carries out artificial fertilization's breeding, and add up later stage farrowing amount etc., following table is corresponding correction data:
Experimental group 1 Matched group 1
Experiment number of elements (only) 100 100
April 4 detected number of elements (only) of oestrusing 91 75
April 4 detected Oestrus rate (%) 91 75
Artificial fertilization's number of elements (only) 91 75
To be fertilized successful number of elements (only) 90 64
Common property lamb number of elements on August 20 (only) 238 135
The ewe of one tire three lamb accounts for and produces sheep ratio (%) 44.4 23.4
Can be found by upper table, this medicament obviously can promote that ewe oestruses ovulation, improves fertilization success rate, increases farrowing quantity, and then improves culture benefit.

Claims (4)

1. promote ewe oestrus ovulation a medicament, it is characterized in that, be made up of the material of following weight portion:
5 ~ 8 parts of Radixs Astragali, 5 ~ 8 parts of Semen Cuscutae, 4 ~ 6 parts of Herba Epimedii, 3 ~ 6 parts of Herba Leonuris, 4 ~ 5 parts of Actinolitum, 3 ~ 4 parts of Herba Taxillis, 2 ~ 4 parts of Rhizoma dioscoreaes, 2 ~ 4 parts of Flos Carthamis, 3 ~ 5 parts of Radix Rehmanniaes Preparata, 4 ~ 6 parts of Herba Cistanches, 2 ~ 4 portions of Fructus Jujubaes, 2 ~ 5 parts of Radix Codonopsis, 3 ~ 6 parts of Fructus Ligustri Lucidi, 1 ~ 2 part of additive.
2. according to claim 1 a kind of promote ewe oestrus ovulation medicament, it is characterized in that, described additive is made up of the material of following weight portion: 5 ~ 10 portions of Sal, 2 ~ 3 parts of aspartames, 1 ~ 3 part of compound vitamin, 0.2 ~ 0.3 part of carbonate rare earth, 0.3 ~ 0.5 part of bacillus titanium zinc.
3. according to claim 2ly a kind ofly promote that ewe oestruses the medicament of ovulation, is characterized in that, containing vitamin A, vitamin D and vitamin E in described compound vitamin.
4. as claimed in claim 1 promote that ewe oestruses the preparation method of medicament of ovulation, is characterized in that, comprises the steps:
(1) 4 ~ 5 parts of Actinolitum are put into crucible, after heating and calcining is aglow, the pure rear pulverizing of yellow wine leaching of pouring its quality 1/4 ~ 1/5 into is for subsequent use;
(2) stirring to faint yellow by putting into hot pot with Testa Tritici after 2 ~ 4 parts of Rhizoma dioscoreae cuttings, cooling for subsequent use after sieve removes wheat bran;
(3) 4 ~ 6 parts of Herba Cistanches to be put into etc. the water of its quality, after soaking 5 ~ 10min, change water at every turn, dry for subsequent use after repetitive operation 3 ~ 4 times;
(4) made for above-mentioned steps material is put into the water of its gross mass 3 ~ 5 times with residual components, after intense fire boils, then use slow fire boiling 15 ~ 20min, after filtration, filtrate is concentrated into the half of original volume.
CN201510937701.2A 2015-12-16 2015-12-16 Agentia for promoting oestrus and ovulation of ewes and preparing method thereof Pending CN105497412A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510937701.2A CN105497412A (en) 2015-12-16 2015-12-16 Agentia for promoting oestrus and ovulation of ewes and preparing method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510937701.2A CN105497412A (en) 2015-12-16 2015-12-16 Agentia for promoting oestrus and ovulation of ewes and preparing method thereof

Publications (1)

Publication Number Publication Date
CN105497412A true CN105497412A (en) 2016-04-20

Family

ID=55705973

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510937701.2A Pending CN105497412A (en) 2015-12-16 2015-12-16 Agentia for promoting oestrus and ovulation of ewes and preparing method thereof

Country Status (1)

Country Link
CN (1) CN105497412A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729283A (en) * 2016-12-29 2017-05-31 中悦民安（北京）科技发展有限公司 A kind of Chinese medicine composition for progestogenic of being promoted the sexual maturity for domestic animal and preparation method thereof
CN107047997A (en) * 2017-06-20 2017-08-18 黄平县华龙生态种养殖有限公司 It is a kind of to be suitable to edible feed of ewe and preparation method thereof before breeding
CN107517924A (en) * 2017-09-30 2017-12-29 东阿阿胶股份有限公司 A kind of illumination, the medication combined method for promoting jenny ass to enter oestrus in advance
CN108338121A (en) * 2018-01-31 2018-07-31 广西东兰县隘洞拉社通达种养专业合作社 The cultural method that sow efficiently farrows
CN108783011A (en) * 2018-08-14 2018-11-13 阜阳师范学院 A kind of feed improving Goat Reproduction ability
CN108887234A (en) * 2018-07-24 2018-11-27 内蒙古中蕴马产业发展有限公司 A method of postponing the breeding season of mare
CN110339315A (en) * 2019-08-09 2019-10-18 内蒙古自治区农牧业科学院 A kind of mongolian veterinary drug feed addictive and preparation method thereof for promoting ewe ovulation to produce twin lamb(s)
CN110432383A (en) * 2019-08-09 2019-11-12 内蒙古自治区农牧业科学院 It is a kind of to promote the sexual maturity the mongolian veterinary drug additive and preparation method thereof of progestogenic for ewe

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1442171A (en) * 2003-01-29 2003-09-17 路春山 Medicinal powder for treating infertility of female animal
CN101940665A (en) * 2010-09-07 2011-01-12 陈鹏举 Aphrodisiac proconceptive traditional Chinese medicine combination for livestock
CN102114153A (en) * 2009-12-31 2011-07-06 天津瑞普生物技术股份有限公司 Traditional Chinese medicine preparation for improving oestrus and pregnancy of dams and preparation method thereof
CN102920993A (en) * 2012-11-28 2013-02-13 河南亚卫动物药业有限公司 Medicament for treating oestrus failure and infertility of female livestock
CN103720993A (en) * 2013-11-15 2014-04-16 北安市飞龙动物药厂 Traditional Chinese medicine composition for improving dam ovulation quality
CN104586932A (en) * 2015-01-22 2015-05-06 河南黑马动物药业有限公司 Traditional Chinese medicine for increasing pregnancy rate of female animals and preparation process thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1442171A (en) * 2003-01-29 2003-09-17 路春山 Medicinal powder for treating infertility of female animal
CN102114153A (en) * 2009-12-31 2011-07-06 天津瑞普生物技术股份有限公司 Traditional Chinese medicine preparation for improving oestrus and pregnancy of dams and preparation method thereof
CN101940665A (en) * 2010-09-07 2011-01-12 陈鹏举 Aphrodisiac proconceptive traditional Chinese medicine combination for livestock
CN102920993A (en) * 2012-11-28 2013-02-13 河南亚卫动物药业有限公司 Medicament for treating oestrus failure and infertility of female livestock
CN103720993A (en) * 2013-11-15 2014-04-16 北安市飞龙动物药厂 Traditional Chinese medicine composition for improving dam ovulation quality
CN104586932A (en) * 2015-01-22 2015-05-06 河南黑马动物药业有限公司 Traditional Chinese medicine for increasing pregnancy rate of female animals and preparation process thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729283A (en) * 2016-12-29 2017-05-31 中悦民安（北京）科技发展有限公司 A kind of Chinese medicine composition for progestogenic of being promoted the sexual maturity for domestic animal and preparation method thereof
CN107047997A (en) * 2017-06-20 2017-08-18 黄平县华龙生态种养殖有限公司 It is a kind of to be suitable to edible feed of ewe and preparation method thereof before breeding
CN107517924A (en) * 2017-09-30 2017-12-29 东阿阿胶股份有限公司 A kind of illumination, the medication combined method for promoting jenny ass to enter oestrus in advance
CN107517924B (en) * 2017-09-30 2021-03-23 东阿阿胶股份有限公司 Method for promoting donkey to enter estrus in advance by combination of illumination and medicines
CN108338121A (en) * 2018-01-31 2018-07-31 广西东兰县隘洞拉社通达种养专业合作社 The cultural method that sow efficiently farrows
CN108887234A (en) * 2018-07-24 2018-11-27 内蒙古中蕴马产业发展有限公司 A method of postponing the breeding season of mare
CN108783011A (en) * 2018-08-14 2018-11-13 阜阳师范学院 A kind of feed improving Goat Reproduction ability
CN110339315A (en) * 2019-08-09 2019-10-18 内蒙古自治区农牧业科学院 A kind of mongolian veterinary drug feed addictive and preparation method thereof for promoting ewe ovulation to produce twin lamb(s)
CN110432383A (en) * 2019-08-09 2019-11-12 内蒙古自治区农牧业科学院 It is a kind of to promote the sexual maturity the mongolian veterinary drug additive and preparation method thereof of progestogenic for ewe

Similar Documents

Publication Publication Date Title
CN105497412A (en) Agentia for promoting oestrus and ovulation of ewes and preparing method thereof
CN101940665B (en) Aphrodisiac proconceptive traditional Chinese medicine combination for livestock
CN102492596B (en) Body-building and health-care medicinal liquor
CN104352776B (en) A kind of hypomenorrhia for the treatment of causes infertile Chinese medicine preparation and preparation method thereof
CN108338121A (en) The cultural method that sow efficiently farrows
CN102940732A (en) Traditional Chinese medicine for adjusting insufficient lactation and agalactosis of sow
CN104784648A (en) Traditional Chinese medicine preparation for anorexia and preparation method of traditional Chinese medicine preparation
CN108403903A (en) A kind of sow with functions of promoting sexual maturity is scattered
CN101293077B (en) Chinese medicinal herb prescription for inducing birth of ricefield eel
CN104322995A (en) Ewe estrus promoting feed and preparation method thereof
CN105248376A (en) Method for increasing postweaning oestrus rate of one-birth sows
CN104958701A (en) Traditional Chinese medicine preparation for HPRL (Hyperprolactinemia) and preparation method of traditional Chinese medicine preparation
CN108837131A (en) A kind of Chinese herbal compounds are promoted the sexual maturity scattered and preparation method thereof
CN104922538A (en) Chinese herbal preparation used for IgA nephropathy and preparing method thereof
CN104800771A (en) Traditional Chinese medicine preparation for treating children sleep terror disorder and preparation method thereof
CN108576341A (en) A kind of coffee and preparation method improving male's sexual
CN103432366B (en) Traditional Chinese medicine formula for treating cow infertility and preparation method and application thereof
CN103638493B (en) Medicine for treating male infertility and preparation method of medicine
CN103211917B (en) Antler plate wine and preparation method thereof
CN105944020A (en) Traditional Chinese medicine for treating ovarian function decrease
CN106071188A (en) A kind of pig feed additive and preparation method thereof and application
CN104306583A (en) Traditional Chinese medicine composition for treating scanty menstruation and preparation method of traditional Chinese medicine composition
CN104906526A (en) Chinese medicine preparation for premature ovarian failure and preparation method of Chinese medicine preparation
CN108432958A (en) A kind of pig feed additive
CN116270878B (en) Traditional Chinese medicine oral liquid for preventing and treating dairy cow mastitis and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160420