CN110327391A - A kind of Chinese veterinary medicinal composition and preparation method thereof for treating Postpartum Cows syndrome of blood stasis due to qi deficiency - Google Patents

A kind of Chinese veterinary medicinal composition and preparation method thereof for treating Postpartum Cows syndrome of blood stasis due to qi deficiency Download PDF

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CN110327391A
CN110327391A CN201910612325.8A CN201910612325A CN110327391A CN 110327391 A CN110327391 A CN 110327391A CN 201910612325 A CN201910612325 A CN 201910612325A CN 110327391 A CN110327391 A CN 110327391A
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deficiency
syndrome
blood stasis
radix
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秦俊杰
白东东
朱浩
侯晓礁
陈立红
李福元
吕慧源
马培倩
王顺山
韩俊国
梁伟
王保山
王秀敏
江厚生
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BEIJING CENTRE BIOLOGY Co Ltd
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Abstract

The invention discloses a kind of Chinese veterinary medicinal compositions and preparation method thereof for treating Postpartum Cows syndrome of blood stasis due to qi deficiency, it is characterized by: 10~40 parts of Radix Astragali, 10~30 parts of Radix Codonopsis, 5~20 parts of motherwort, Radix Angelicae Sinensis 5~15,5~15 parts of Rhizoma Chuanxiong, 5~15 parts of Radix Glycyrrhizae, 10~30 parts of jujube, 5-20 parts of Cortex Magnoliae Officinalis, corresponding preparations are made by the preparation process of required dosage form.The invention has the benefit that showing through correlation test, it has the benefits of benefiting qi and nourishing blood, activating microcirculation and removing stasis medicinal, both can tonifying spleen lung gas, lifting disease, but can nourshing blood and promoting blood circulation, tonifying blood and regulating menstruation, and drug of the invention be pure Chinese medicinal preparation, it is environmentally protective, the noresidue in Contents in Cows is suitable for all Postpartum Cows syndrome of blood stasis due to qi deficiency, can also significantly reduce the disease incidence of Postpartum Cows qi deficiency to blood stasis associated diseases.

Description

A kind of Chinese veterinary medicinal composition and preparation method thereof for treating Postpartum Cows syndrome of blood stasis due to qi deficiency
Technical field
The invention belongs to milk cow field of pharmaceutical technology, and in particular to a kind of for treating in Postpartum Cows syndrome of blood stasis due to qi deficiency Animal medicinal composition and preparation method thereof.
Background technique
Milk cow is known as mother of baby, the lifelong nurse of the mankind, ensures milk cow health, improves the output of milk, to promoting me State's milk industry develops in a healthy way, raising people's living standard is significant.Milk cow postpartum is in poor health, and lactation activity is reinforced in addition, battalion Support metabolism be in negative balance, resistance weaken, a variety of diseases easily occur, as retention of afterbirth, hysteritis, the subinvolution of uterus, Indigestion, hypogalactia, lochiorrhagia even infertility etc., seriously affect the health and its production performance of milk cow.Chinese medicine thinks " to produce Thin fluid injury afterwards, vigour is impaired, and remaining blood turbid is not most ", therefore postpartum " healthy tendency is easily empty, susceptible disease and evil, easily raw to be retarded by silt ".Blood is in arteries and veins It flows round without stopping in pipe, the impetus of full Lai Yuqi.This power is realized by the activity of viscera function.If internal organs function It can weaken or fail, the deficiency of vital energy cannot push blood to run in vascular, and the blood that is bound to is powerless, and blood flow is slow or is retarded by silt, pole Easily cause a variety of postpartum diseases.The disease caused at present about milk cow postpartum qi deficiency to blood stasis is clinically mostly with antibiotic treatment Based on, but since the problems such as it easily leads to bacterial drug resistance generation, off-drug period length, medicament residue and food safety is to a certain degree On limit the clinical application of antibiotic, and in terms of Chinese veterinarian, crude drug source is extensive, cheap, environmentally protective, and is controlling Treating ox postpartum syndrome of blood stasis due to qi deficiency has clinical experience very rich.
Summary of the invention
The present invention is directed to various drawbacks for above-mentioned treatment technology and insufficient, based on Chinese veterinarian's theory, in conjunction with facing Bed practical experience, provides a kind of for treating the Chinese veterinary medicinal composition of Postpartum Cows syndrome of blood stasis due to qi deficiency.
To achieve the above object, inventor is studied by long-term practice based on Chinese veterinarian's pharmacology opinion, is filtered out this hair Mode is implemented as follows in bright formula, main use:
A kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency, drug composition are indicated with parts by weight are as follows: 5~60 parts of Radix Astragali, 5~50 parts of Radix Codonopsis, 3~30 parts of motherwort, Radix Angelicae Sinensis 3~30,3~30 parts of Rhizoma Chuanxiong, 3~30 parts of Radix Glycyrrhizae, jujube 5 ~50 parts, 3~30 parts of Cortex Magnoliae Officinalis.
A kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency, drug composition are indicated with parts by weight are as follows: It is 10~40 parts of Radix Astragali, 10~30 parts of Radix Codonopsis, 10~20 parts of motherwort, Radix Angelicae Sinensis 5~15,5~15 parts of Rhizoma Chuanxiong, 5~15 parts of Radix Glycyrrhizae, big 10~30 parts of jujube, 5~20 parts of Cortex Magnoliae Officinalis.
A kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency, drug composition is indicated with parts by weight, excellent It is selected as: 25 parts of Radix Astragali, 15 parts of Radix Codonopsis, 10 parts of motherwort, Radix Angelicae Sinensis 10,10 parts of Rhizoma Chuanxiong, 10 parts of Radix Glycyrrhizae, 20 parts of jujube, 10 parts of Cortex Magnoliae Officinalis.
The present invention is made using industry universal method water extraction, specifically: number weighs each medicinal material according to the required weight, is added The water of 10~12 times of medicinal material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging is filtered twice Liquid, filtrate decompression are concentrated into relative density 1.15~1.20 (60 DEG C), corresponding preparations are made by the preparation process of required dosage form, i.e., ?.
The application method of composition described in the present invention is: using above-mentioned composition as raw material, corresponding auxiliary material is added, into one Step is prepared into the internal dosage forms such as oral solution, pulvis, granule.
Prescription and its principle of the invention:
Chinese veterinarian is dialectical to think that the Postpartum Cows syndrome of blood stasis due to qi deficiency cause of disease is complicated, and the cause of disease has: (1) the gas consumption deficiency of blood.Gas consumption blood Void can cause the Yang-function insufficiency of kidneyzang, and gasify not normal, excretion disorder, and aqueous, which is spread unchecked, causes diarrhea and oedema;It can cause weakness of the spleen and the stomach, cause milk cow Postpartum does not eat;Uterus can be made to shrink powerless, retention of afterbirth and postpartum uterine disease occurs.(2) blood-stasis internal-depression.Blood-stasis internal-depression or tire The punching of clothing remaining influence is appointed, and the escape of blood from vessels and channels can cause lochiorrhagia;Hemostasis is stopped up stagnant and can cause postpartum fever;Retention of blood stasis, gaseous pulse are stopped up stagnant Still cause galactostasis.(3) postpartum exogenous disease.Postpartum, qi and blood consume, interspaces of skin and muscles being loose, hundred sections were hollow, and exopathogen multiplies due to excessive blood loss Void invasion, and cause zang-fu diseases;Or exopathogen invading the interior, change hot air wind producing, qi and blood stagnation, and cause pain or fever.It sums up i.e. ancient People's so-called postpartum is more " qi deficiency to blood stasis ", and susceptible exopathogen, all diseases are outstanding raw.Be thus benefiting qi and nourishing blood, activating microcirculation and removing stasis medicinal for prevention and treatment postartum disease Effective ways.In prescription of the present invention, the gas of the big tonifying spleen lung of Radix Astragali is reused, is monarch drug in a prescription as a means of the source of green blood;Radix Codonopsis bowl spares benefit Gas, nourishes blood and promotes the production of body fluid, Chinese angelica blood supplementing promoting blood circulation, menstruction regulating and pain relieving, the two amount to, and make YANG promoting growth while YIN promoting generation, and the prosperous blood of gas is raw, and enhancing Radix Astragali lifts sun The power of gas is altogether ministerial drug;Motherwort promoting blood circulation adjusting, the promoting flow of qi and blood, Rhizoma Chuanxiong, Cortex Magnoliae Officinalis blood-activating and qi-promoting, wind-expelling pain-stopping etc., San Zhehe Altogether, replenishing and activating blood, qi being the governor of blood, blood being the material foundation of QI, the prosperous then gas foot of blood, is altogether adjutant;Radix Glycyrrhizae, jujube benefiting qi and nourishing blood, emergency Analgesic, coordinating the drug actions of a prescription, to make medicine.All medicines share has the effect of benefiting qi and nourishing blood, activating microcirculation and removing stasis medicinal.
The present invention has following an advantage and effect compared with the existing technology: the present invention is that a kind of source natural plants are used for The Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency, by way of the administration for oral administration, with benefiting qi and nourishing blood, activating microcirculation and removing stasis medicinal The rules for the treatment of, multipath adjust Postpartum Cows syndrome of blood stasis due to qi deficiency, can significantly mitigate the clinical symptoms of postpartum syndrome of blood stasis due to qi deficiency milk cow, reduce The disease incidence of Postpartum Cows qi deficiency to blood stasis associated diseases.
Specific embodiment
The present invention will be further explained with reference to the examples below, as described below, is only to preferable implementation of the invention Example, not limits the present invention, any person skilled in the art is possibly also with the disclosure above Technology contents be changed to the equivalent embodiment changed on an equal basis.Without departing from the concept of the present invention, according to the present invention Technical spirit any simple modification or equivalent variations that following embodiment is made, fall within the scope of protection of the present invention.
Embodiment 1: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of: Radix Astragali agents It is total that medicinal material is added in 15 parts, 10 parts of Radix Codonopsis, 5 parts of motherwort, 5 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Chuanxiong, 5 parts of Radix Glycyrrhizae, 10 parts of jujube, 10 parts of Cortex Magnoliae Officinalis The water of 10 times of weight amounts, immersion 0.5 hour are decocted three times, are decocted 1.0 hours every time, and filtration, filtrate, filtrate subtract twice for merging Pressure is concentrated into relative density 1.12 (60 DEG C), and sodium benzoate 3.5g is added, and is mixed, is let cool, and filtrate adds water adjustment total amount extremely 1000ml, sterilizing, the filling Traditional Chinese veterinary medicine oral solution to get for treating Postpartum Cows syndrome of blood stasis due to qi deficiency.
Embodiment 2: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicine is added in 25 parts of stilbene, 15 parts of Radix Codonopsis, 10 parts of motherwort, Radix Angelicae Sinensis 10,10 parts of Rhizoma Chuanxiong, 10 parts of Radix Glycyrrhizae, 20 parts of jujube, 10 parts of Cortex Magnoliae Officinalis The water of 10 times of material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, and filtration merges filtrate twice, filter Liquid is concentrated under reduced pressure into relative density 1.12 (60 DEG C), and sodium benzoate 3.5g is added, and is mixed, is let cool, and filtrate adds water adjustment total amount extremely 1000ml, sterilizing, the filling Traditional Chinese veterinary medicine oral solution to get for treating Postpartum Cows syndrome of blood stasis due to qi deficiency.
Embodiment 3: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicine is added in 35 parts of stilbene, 20 parts of Radix Codonopsis, 30 parts of motherwort, 15 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 5 parts of Radix Glycyrrhizae, 20 parts of jujube, 20 parts of Cortex Magnoliae Officinalis The water of 10 times of material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, and filtration merges filtrate twice, filter Liquid is concentrated under reduced pressure into relative density 1.12 (60 DEG C), and sodium benzoate 3.5g is added, and is mixed, is let cool, and filtrate adds water adjustment total amount extremely 1000ml, sterilizing, the filling Traditional Chinese veterinary medicine oral solution to get for treating Postpartum Cows syndrome of blood stasis due to qi deficiency.
Embodiment 4: not following the parts by weight relationship of this formulation of drug, arbitrarily carry out prescription, weighs 35 parts of Radix Astragali, party Join 24 parts, 15 parts of motherwort, 8 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Chuanxiong, 12 parts of Radix Glycyrrhizae, 10 parts of jujube, 14 parts of Cortex Magnoliae Officinalis, medicinal material total weight 10 is added The water of amount again impregnates 0.5 hour, decocts three times, every time decoction 1.0 hours, filtration, and merging filtrate, filtrate decompression is concentrated into phase To density 1.12 (60 DEG C), sodium benzoate 3.5g is added, mixes, lets cool, filtrate adds water to adjust total amount to 1000ml, sterilizes, fills Dress is to get the Traditional Chinese veterinary medicine oral solution for treating Postpartum Cows syndrome of blood stasis due to qi deficiency.
Embodiment 5: not following the compatibility relationship of this formulation of drug, arbitrarily chooses formulation of drug and carries out prescription, weighs The water of 10 times of medicinal material total weight amounts is added in 20 parts of Radix Astragali, 10 parts of Radix Codonopsis, 15 parts of motherwort, 5 parts of Rhizoma Chuanxiong, 10 parts of jujube, impregnates It 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate decompression is concentrated into relative density 1.12 (60 DEG C), sodium benzoate 3.5g is added, mixes, lets cool, filtrate adds water to adjust total amount to 1000ml, and sterilizing is filling to get for controlling Treat the Traditional Chinese veterinary medicine oral solution of Postpartum Cows syndrome of blood stasis due to qi deficiency.
Embodiment 6: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicine is added in 10 parts of stilbene, 20 parts of Radix Codonopsis, 10 parts of motherwort, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 5 parts of Radix Glycyrrhizae, 20 parts of jujube, 10 parts of Cortex Magnoliae Officinalis The water of 10 times of material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate subtracts Pressure is concentrated into relative density 1.17 (60 DEG C), is spray-dried, and glucose is added and adjusts total amount to 200g to get for treating postpartum The herbal medicine pulvis of milk cow syndrome of blood stasis due to qi deficiency.
Embodiment 7: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicine is added in 30 parts of stilbene, 10 parts of Radix Codonopsis, 20 parts of motherwort, 5 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 10 parts of Radix Glycyrrhizae, 10 parts of jujube, 5 parts of Cortex Magnoliae Officinalis The water of 10 times of material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate subtracts Pressure is concentrated into relative density 1.20 (60 DEG C), is spray-dried, and glucose is added and adjusts total amount to 200g to get for treating postpartum The herbal medicine pulvis of milk cow syndrome of blood stasis due to qi deficiency.
Embodiment 8: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang 20 parts of stilbene, 15 parts of Radix Codonopsis, 15 parts of motherwort, 10 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 10 parts of Radix Glycyrrhizae, 30 parts of jujube, 20 parts of Cortex Magnoliae Officinalis are added The water of 10 times of medicinal material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate It is concentrated under reduced pressure into relative density 1.17 (60 DEG C), is spray-dried, glucose adjustment total amount is added and is produced to 200g to get for treating The herbal medicine pulvis of milk cow syndrome of blood stasis due to qi deficiency afterwards.
Embodiment 9: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicinal material is added in 15 parts of stilbene, 10 parts of Radix Codonopsis, 10 parts of motherwort, 10 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Chuanxiong, 5 parts of Radix Glycyrrhizae, 20 parts of jujube, 5 parts of Cortex Magnoliae Officinalis The water of 10 times of total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate decompression It is concentrated into relative density 1.18 (60 DEG C), is spray-dried, obtains extract;Add dextrin 200g, sucrose 50g, carboxymethyl cellulose Plain sodium 20g is mixed, and using 70% ethyl alcohol as wetting agent, particle is made, dry to get for treating Postpartum Cows qi deficiency to blood stasis The veterinary drug granules of card.
Embodiment 10: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicine is added in 25 parts of stilbene, 15 parts of Radix Codonopsis, 20 parts of motherwort, 5 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 10 parts of Radix Glycyrrhizae, 30 parts of jujube, 15 parts of Cortex Magnoliae Officinalis The water of 10 times of material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate subtracts Pressure is concentrated into relative density 1.18 (60 DEG C), is spray-dried, is obtained extract;It is fine to add dextrin 200g, sucrose 50g, carboxymethyl Plain sodium 20g is tieed up, is mixed, using 70% ethyl alcohol as wetting agent, particle is made, it is dry to get for treating Postpartum Cows deficiency of vital energy blood The veterinary drug granules of stasis syndrome.
Embodiment 11: a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency is made of agents: taking Huang Medicine is added in 35 parts of stilbene, 20 parts of Radix Codonopsis, 10 parts of motherwort, 15 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Chuanxiong, 15 parts of Radix Glycyrrhizae, 10 parts of jujube, 10 parts of Cortex Magnoliae Officinalis The water of 10 times of material total weight amounts impregnates 0.5 hour, decocts three times, decocts 1.0 hours every time, filtration, merging filtrate, filtrate subtracts Pressure is concentrated into relative density 1.19 (60 DEG C), is spray-dried, is obtained extract;It is fine to add dextrin 200g, sucrose 50g, carboxymethyl Plain sodium 20g is tieed up, is mixed, using 70% ethyl alcohol as wetting agent, particle is made, it is dry to get for treating Postpartum Cows deficiency of vital energy blood The veterinary drug granules of stasis syndrome.
The clinical test for treating Postpartum Cows syndrome of blood stasis due to qi deficiency
(1) test material
Animal: clinical signs go out Postpartum Cows 90 of syndrome of blood stasis due to qi deficiency.
Trial drug: Traditional Chinese veterinary medicine oral solution made from Examples 1 to 5 is to should be used as one~medical fluid of medical fluid five.
(2) method and result
Clinical symptoms with Postpartum Cows syndrome of blood stasis due to qi deficiency: 1. constitution is thin and weak, in nutrition under, the shrivelled tarnish of coat; 2. force of labor is weak, prolonged labor;3. fortune step is out of strength, crouch how vertical few;4. appetite stimulator, feed intake decline;5. defecate it is dilute rush down, number increase Add;6. arteria caudalis is weak.7. labia swelling is turned up;8. lochia efflux time extends, color purple is dim grumeleuse;9. abdominal pain is uneasy;⑩ Delivery time extends or retention of afterbirth.Above-mentioned clinical symptoms, which must meet 4 or so, can be diagnosed as Postpartum Cows qi deficiency to blood stasis Card.
Treatment method: will suffer from the milk cow of postpartum syndrome of blood stasis due to qi deficiency, be included in sequence according to case, random according to clinical research Change scheme requires to be divided into 6 groups, every group 15, respectively one group of medical fluid, two groups of medical fluid, three groups of medical fluid, four groups of medical fluid, medical fluid five Group and blank control group (hereinafter referred to as control group).
Five groups of one group~medical fluid of medical fluid: one~medical fluid of administered by oral gavage 500mL medical fluid five is distinguished in the set time daily, daily 1 time, 30d is observed continuously in successive administration 5d.
Control group: 30d is observed continuously in the daily set time administered by oral gavage 500mL physiological saline of every ox.
Curative effect determinate standard: test is counted according to postpartum syndrome of blood stasis due to qi deficiency diagnostic criteria by head with ox, each symptom presses nothing (0 point), light (1 point), in (2 points), (3 points) progresss quantization modulations accumulations are scored again, observe pretherapy and post-treatment integral and change.Respectively It is respectively recorded 1 time before medication, after medication and after withdrawal observation.Therapeutic effect of syndrome rate=(pre-treatment score-post treatment integral)/ Pre-treatment score × 100%.
Effective: Chinese veterinarian's symptom is substantially reduced after treatment, therapeutic effect of syndrome rate >=70%;;
Effective: Chinese veterinarian's symptom mitigates after treatment, 30%≤therapeutic effect of syndrome rate < 70%;
Invalid: Chinese veterinarian's symptom is not improved or aggravates after treatment, therapeutic effect of syndrome rate < 30%.
Therapeutic effect statistics is specifically shown in Tables 1 and 2.
1 Postpartum Cows syndrome of blood stasis due to qi deficiency treatment results statistical form of table
Note: it is handled in integral statistics using 20.0 one-way analysis of variance of SPSS, as a result each group is compared with before administration, * table Show significant difference (P < 0.05), * * indicates that difference is extremely significant (P < 0.01);It is compared between group, different lowercase letter indication differences are significant (P < 0.05), different capitalizations indicate that difference is extremely significant (P < 0.01);Total effective rate uses 20.0 Chi-square Test of SPSS, together Sample difference lowercase letter indication difference is significant (P < 0.05), and different capitalizations indicate that difference is extremely significant (P < 0.01).
As can be seen from Table 1, before administration, there was no significant difference (P > 0.05) for each group Postpartum Cows integral;Administration 5 days Afterwards, one group~medical fluid of medical fluid, three groups of integrals with administration before compared with difference it is extremely significant (P < 0.01), with four groups of medical fluid, five groups of medical fluid and Control group integral compares significant difference (P < 0.05), five groups of four groups of medical fluid and medical fluid compared with before administration significant difference (P < 0.05);After being observed continuously 30 days, one group~medical fluid of medical fluid, five groups of integrals difference compared with before administration is extremely significant (P < 0.01), medicine Three groups of one group~medical fluid of the liquid difference compared with four groups of medical fluid, five groups of medical fluid and control group integral is extremely significant (P < 0.01), control group The significant difference (P < 0.05) compared with five groups of integrals of four groups of medical fluid and medical fluid;Total effective rate is after Chi-square Test, with medical fluid two Group is compared, and one group of medical fluid, there was no significant difference (P > 0.05) for three groups of total effective rates of medicine company, four groups of medical fluid, five groups of medical fluid and control Group total effective rate difference is extremely significant (P < 0.01), compared with the control group, three groups of one group of medical fluid, medical fluid total effective rate significant difference (P <0.05), three groups of differences of medical fluid are extremely significant (P<0.01), five groups of total effective rate differences of four groups of medical fluid and medical fluid it is not significant (P> 0.05), the above result shows that one group~medical fluid of medical fluid, three groups for the treatment of Postpartum Cows syndrome of blood stasis due to qi deficiency significant effects are better than medical fluid four Group, five groups of medical fluid and control group, two groups of clinical efficacies of Chinese medicine liquid are best.
2 Chinese veterinary medicinal composition of table is to each group milk cow postpartum morbidity statistical form
As can be seen from Table 2, in the influence for Chinese veterinary medicinal composition to the disease incidence of Postpartum Cows, two groups of medical fluid cause Disease incident it is minimum, only 6.67%, be lower than other medical fluid groups and control group, can it can be seen from the table, one group of medical fluid~ The disease incident of five groups of initiations of medical fluid will be lower than control group, illustrate Chinese veterinary medicinal composition and can reduce Postpartum Cows illness and is several Rate, and two groups of effects of medical fluid are best.
It is preferably controlled the above test results show that Chinese veterinary medicinal composition of the invention has Postpartum Cows syndrome of blood stasis due to qi deficiency Therapeutic effect can be relieved the clinical symptoms of postpartum syndrome of blood stasis due to qi deficiency milk cow, and can reduce Postpartum Cows qi deficiency to blood stasis to a certain extent Card causes the disease incidence of other diseases.

Claims (5)

1. a kind of Chinese veterinary medicinal composition for treating Postpartum Cows syndrome of blood stasis due to qi deficiency, which is characterized in that by the original of following parts by weight Material medicine is made: 5~60 parts of Radix Astragali, 5~50 parts of Radix Codonopsis, 3~50 parts of motherwort, Radix Angelicae Sinensis 3~30,3~30 parts of Rhizoma Chuanxiong, Radix Glycyrrhizae 3~ 30 parts, 5~50 parts of jujube, 3~30 parts of Cortex Magnoliae Officinalis.
2. the Chinese veterinary medicinal composition for the treatment of milk cow syndrome of blood stasis due to qi deficiency according to claim 1, which is characterized in that the medicine The parts by weight of each bulk pharmaceutical chemicals in object composition are as follows: 10~40 parts of Radix Astragali, 10~30 parts of Radix Codonopsis, 10~30 parts of motherwort, Radix Angelicae Sinensis 5~ 15,5~15 parts of Rhizoma Chuanxiong, 5~15 parts of Radix Glycyrrhizae, 10~30 parts of jujube, 5-20 parts of Cortex Magnoliae Officinalis.
3. according to claim 1, treating the Chinese veterinary medicinal composition of milk cow syndrome of blood stasis due to qi deficiency described in 2, it is characterised in that described Bulk pharmaceutical chemicals are preferred based on parts by weight are as follows: 25 parts of Radix Astragali, 20 parts of Radix Codonopsis, 15 parts of motherwort, Radix Angelicae Sinensis 10,10 parts of Rhizoma Chuanxiong, Radix Glycyrrhizae 10 Part, 20 parts of jujube, 10 parts of Cortex Magnoliae Officinalis.
4. according to claim 1, treating the Chinese veterinary medicinal composition of milk cow syndrome of blood stasis due to qi deficiency described in 2,3, which is characterized in that described Bulk pharmaceutical chemicals the preparation method is as follows: number weighs each medicinal material according to the required weight, 10~12 times of amount water of medicinal material total weight, immersion is added It 0.5 hour, decocts three times, 1 hour every time, filtration, merging filtrate, filtrate decompression is concentrated into relative density 1.15~1.20 (60 DEG C), corresponding preparations are made by the preparation process of required dosage form.
5. Chinese veterinary medicinal composition described in claims 1 to 3 any one is in the drug of preparation treatment milk cow syndrome of blood stasis due to qi deficiency Application.
CN201910612325.8A 2019-07-09 2019-07-09 A kind of Chinese veterinary medicinal composition and preparation method thereof for treating Postpartum Cows syndrome of blood stasis due to qi deficiency Pending CN110327391A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110960610A (en) * 2019-12-23 2020-04-07 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicine composition for preventing and treating qi deficiency type retained fetal membranes of dairy cows and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110960610A (en) * 2019-12-23 2020-04-07 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicine composition for preventing and treating qi deficiency type retained fetal membranes of dairy cows and preparation method thereof

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