CN110290817B - 转谷氨酰胺酶处理的产品 - Google Patents

转谷氨酰胺酶处理的产品 Download PDF

Info

Publication number
CN110290817B
CN110290817B CN201880009304.0A CN201880009304A CN110290817B CN 110290817 B CN110290817 B CN 110290817B CN 201880009304 A CN201880009304 A CN 201880009304A CN 110290817 B CN110290817 B CN 110290817B
Authority
CN
China
Prior art keywords
tissue
collagen
matrix
transglutaminase
tissue matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201880009304.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN110290817A (zh
Inventor
怡·陈
肖恩·柯林斯
黄励婷
埃里克·斯特克
辉·许
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LifeCell Corp
Original Assignee
LifeCell Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LifeCell Corp filed Critical LifeCell Corp
Priority to CN202010506398.1A priority Critical patent/CN111544652A/zh
Publication of CN110290817A publication Critical patent/CN110290817A/zh
Application granted granted Critical
Publication of CN110290817B publication Critical patent/CN110290817B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/362—Skin, e.g. dermal papillae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254—Enzymes, proenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
CN201880009304.0A 2017-01-30 2018-01-29 转谷氨酰胺酶处理的产品 Active CN110290817B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010506398.1A CN111544652A (zh) 2017-01-30 2018-01-29 转谷氨酰胺酶处理的产品

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762452000P 2017-01-30 2017-01-30
US62/452,000 2017-01-30
PCT/US2018/015684 WO2018140853A1 (en) 2017-01-30 2018-01-29 Transglutaminase treated products

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010506398.1A Division CN111544652A (zh) 2017-01-30 2018-01-29 转谷氨酰胺酶处理的产品

Publications (2)

Publication Number Publication Date
CN110290817A CN110290817A (zh) 2019-09-27
CN110290817B true CN110290817B (zh) 2020-07-03

Family

ID=61224534

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201880009304.0A Active CN110290817B (zh) 2017-01-30 2018-01-29 转谷氨酰胺酶处理的产品
CN202010506398.1A Pending CN111544652A (zh) 2017-01-30 2018-01-29 转谷氨酰胺酶处理的产品

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202010506398.1A Pending CN111544652A (zh) 2017-01-30 2018-01-29 转谷氨酰胺酶处理的产品

Country Status (7)

Country Link
US (4) US10413634B2 (enExample)
EP (1) EP3573674A1 (enExample)
JP (1) JP6942191B2 (enExample)
CN (2) CN110290817B (enExample)
AU (1) AU2018212908A1 (enExample)
CA (1) CA3051145A1 (enExample)
WO (1) WO2018140853A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10413634B2 (en) * 2017-01-30 2019-09-17 Lifecell Corporation Transglutaminase treated products
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
JP2022535105A (ja) * 2019-06-07 2022-08-04 ライフセル コーポレーション コーティングされたポリマー材料
CN113081482B (zh) * 2021-04-23 2024-02-27 柏为（武汉）医疗科技股份有限公司 一种中耳防粘连膜及其制备方法

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5230097A (en) 1975-09-02 1977-03-07 Kaneyasu Miyata Method of mounting different substitute blood vessel
US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
CA2051092C (en) 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
US8067149B2 (en) 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
US5374539A (en) 1991-06-17 1994-12-20 Nimni; Marcel E. Process for purifying collagen and generating bioprosthesis
US5549904A (en) * 1993-06-03 1996-08-27 Orthogene, Inc. Biological adhesive composition and method of promoting adhesion between tissue surfaces
WO1996032905A1 (en) 1995-04-19 1996-10-24 St. Jude Medical, Inc. Matrix substrate for a viable body tissue-derived prosthesis and method for making the same
US5782915A (en) 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts
US6166288A (en) 1995-09-27 2000-12-26 Nextran Inc. Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
DK0942739T3 (da) 1996-12-10 2006-07-17 Purdue Research Foundation Biomateriale afledt fra hvirveldyrlevervæv
DE19828726A1 (de) 1997-06-27 1999-01-07 Augustinus Dr Bader Bioartifizielles Transplantat und Verfahren zu seiner Herstellung
FR2769721B1 (fr) * 1997-10-10 2001-01-26 Sextant Avionique Dispositif optique pour viseur de casque comportant un miroir de mangin
US6123731A (en) * 1998-02-06 2000-09-26 Osteotech, Inc. Osteoimplant and method for its manufacture
AU759086B2 (en) 1998-03-06 2003-04-03 Crosscart, Inc. Soft tissue xenografts
US6383732B1 (en) 1999-02-11 2002-05-07 Crosscart, Inc. Method of preparing xenograft heart valves
CA2332986C (en) 1998-05-26 2009-09-08 Lifecell Corporation Cryopreservation of human red blood cells
US6267786B1 (en) 1999-02-11 2001-07-31 Crosscart, Inc. Proteoglycan-reduced soft tissue xenografts
US20030068815A1 (en) 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
US20070009586A1 (en) 2000-02-29 2007-01-11 Cohen Kelman I Wound dressings containing complexes of transition metals and alginate for elastase sequestering
GB0011356D0 (en) * 2000-05-12 2000-06-28 Univ Nottingham Trent Medical implant materials
EP1315796B1 (en) 2000-08-16 2006-07-12 Duke University Decellularized tissue engineered constructs and tissues
JP2004529711A (ja) 2001-05-07 2004-09-30 クロスカート インコーポレイテッド 粘膜下異種移植片
TWI284665B (en) 2001-08-17 2007-08-01 Univ Nat Cheng Kung Fabrication method of the porous collagen matrix
ES2672815T3 (es) 2001-10-18 2018-06-18 Lifecell Corporation Remodelación de tejidos y órganos
US8308797B2 (en) 2002-01-04 2012-11-13 Colibri Heart Valve, LLC Percutaneously implantable replacement heart valve device and method of making same
US7919121B2 (en) 2002-01-11 2011-04-05 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
WO2003087464A1 (en) 2002-04-05 2003-10-23 Novozymes North America, Inc. Improvement of strength and abrasion resistance of durable press finished cellulosic materials
AUPS242702A0 (en) 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US6835385B2 (en) 2002-06-14 2004-12-28 Carol J. Buck Compositions and methods for softening, thinning and removing hyperkeratotic tissue
AU2003211379A1 (en) 2002-08-28 2004-03-19 Kinki University Process for producing collagen treated with cysteine protease and collagen treated with cysteine protease
JP3658385B2 (ja) 2002-09-20 2005-06-08 佳宏 高見 皮膚の無細胞化方法、該方法による無細胞化真皮マトリックス及びその製造方法並びに該マトリックスを用いた複合培養皮膚
US20040191226A1 (en) 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
US20040176855A1 (en) 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
EP1651050B1 (en) 2003-07-21 2012-08-22 Lifecell Corporation Acellular tissue matrices made from galactose alpha-1,3-galactose -deficient tissue
US7901461B2 (en) * 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
US20050186286A1 (en) 2004-02-25 2005-08-25 Yoshihiro Takami Skin decellularization method, acellular dermal matrix and production method therefore employing said decellularization method, and composite cultured skin employing said matrix
CA2559720A1 (en) 2004-03-17 2005-09-29 Revivicor, Inc. Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase
GB0420091D0 (en) * 2004-09-10 2004-10-13 Univ Nottingham Trent Medical implant materials
US20060073592A1 (en) 2004-10-06 2006-04-06 Wendell Sun Methods of storing tissue matrices
WO2006074373A2 (en) 2005-01-06 2006-07-13 Crosscart, Inc. Immunochemically modified and sterilized xenografts and allografts
US9216236B2 (en) 2005-03-07 2015-12-22 Technion Research & Development Foundation Limited Natural tissue-derived decellularized matrix and methods of generating and using same
GB0515003D0 (en) * 2005-07-21 2005-08-31 Univ Aston Medical devices and coatings therefor
EP2965769B1 (en) 2005-08-26 2018-12-26 Regents of the University of Minnesota Decellularization and recellularization of organs and tissues
JP5002805B2 (ja) 2005-10-14 2012-08-15 財団法人ヒューマンサイエンス振興財団 生物由来スキャフォールドの作製方法
US20070248575A1 (en) 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
JP5050197B2 (ja) 2006-07-31 2012-10-17 財団法人ヒューマンサイエンス振興財団 生物由来スキャフォールドの作製方法
WO2008076407A2 (en) * 2006-12-15 2008-06-26 Lifebond Ltd. Gelatin-transglutaminase hemostatic dressings and sealants
US8361503B2 (en) 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
AU2008237733A1 (en) 2007-04-16 2008-10-23 Tissue Science Laboratories Plc Vascular implant
WO2008125850A2 (en) 2007-04-16 2008-10-23 Tissue Science Laboratories Plc Methods and compositions for tissue regeneration
US20100119577A1 (en) 2007-05-06 2010-05-13 Byoung-Hyun Min Therapeutic composite for cartilage disorder using extracellular matrix (ecm) scaffold
EP2011524A1 (en) * 2007-07-02 2009-01-07 Omrix Biopharmaceuticals Ltd. Fibrin glue with a visualization agent
AU2008275072B2 (en) 2007-07-10 2013-03-14 Lifecell Corporation Acellular tissue matrix compositions for tissue repair
CZ301086B6 (cs) 2007-10-17 2009-11-04 Bio-Skin, A. S. Sterilní autologní, allogenní nebo xenogenní implantát a zpusob jeho výroby
TWI353845B (en) 2008-03-19 2011-12-11 Food Industry Res & Dev Inst Process for preparing peptide products for promoti
GB0807868D0 (en) 2008-04-30 2008-06-04 Knight David P Cartilage repair material and a method for the preparation thereof
EP3581214A1 (en) 2008-06-06 2019-12-18 LifeCell Corporation Elastase treatment of tissue matrices
AU2009261559B2 (en) 2008-06-18 2014-01-16 Lifebond Ltd Improved cross-linked compositions
AU2009267181A1 (en) 2008-07-01 2010-01-07 Cook Biotech Incorporated Isolated extracellular matrix material including subserous fascia
US7927414B2 (en) 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
PL2398502T3 (pl) 2009-02-18 2016-03-31 Cormatrix Cardiovascular Inc Kompozycje i sposoby do zapobiegania zaburzeniu rytmu serca
CA2753684A1 (en) 2009-03-02 2010-09-10 The Children's Mercy Hospital Tissue engineered human pulmonary valves with cyclic pressure bioreactor accelerated seeding strategies and methods for assessing inflammatory potential of putative scaffolds fortissue engineered heart valves
US9155323B2 (en) 2009-05-15 2015-10-13 Siebte Pmi Verwaltungs Gmbh Aqueous process for preparing protein isolate and hydrolyzed protein from an oilseed
US8198408B2 (en) 2009-07-27 2012-06-12 National Cheng Kung University Method for preparing porous collagen matrices
WO2011014155A1 (en) 2009-07-27 2011-02-03 National Cheng Kung University Preparation of high purity collagen
EP3545980A1 (en) 2010-02-26 2019-10-02 DeCell Technologies Inc. Methods for tissue decellularization
EP2590691B1 (en) 2010-07-08 2019-09-04 LifeCell Corporation Method for shaping tissue matrices
GB2482166A (en) 2010-07-22 2012-01-25 Tissue Science Lablratories Ltd Manufacture of collagenous material from use in therapy from collagen particles
DK2600910T3 (en) 2010-08-05 2016-04-04 Lifebond Ltd Wound dressings and adhesives COMPREHENSIVE DRYING FORMATIONS
WO2012030805A2 (en) * 2010-08-30 2012-03-08 President And Fellows Of Harvard College A high strength chitin composite material and method of making
US10207025B2 (en) 2011-04-28 2019-02-19 Lifecell Corporation Method for enzymatic treatment of tissue products
EP3473278B1 (en) * 2011-04-28 2020-10-28 LifeCell Corporation Method for enzymatic treatment of tissue products
US9238793B2 (en) 2011-04-28 2016-01-19 Lifecell Corporation Method for enzymatic treatment of tissue products
CA2837196C (en) 2011-05-31 2020-03-24 Lifecell Corporation Adipose tissue matrices
CN103816562B (zh) * 2013-12-02 2016-01-13 华东师范大学 一种战争创伤快速止血产品及其制备方法
CN105802251B (zh) * 2016-04-25 2019-09-17 成都大学 一种自组装胶原模板组织工程材料及其制备方法与应用
JP7143222B2 (ja) * 2016-05-09 2022-09-28 ライフボンド リミテッド メッシュベースのインサイチュ架橋性組成物
US10413634B2 (en) * 2017-01-30 2019-09-17 Lifecell Corporation Transglutaminase treated products
AU2018212909B2 (en) 2017-01-30 2023-12-14 Lifecell Corporation Tissue matrix materials and enzymatic adhesives

Also Published As

Publication number Publication date
WO2018140853A1 (en) 2018-08-02
US10814033B2 (en) 2020-10-27
US20210015970A1 (en) 2021-01-21
CN111544652A (zh) 2020-08-18
CA3051145A1 (en) 2018-08-02
US11724004B2 (en) 2023-08-15
JP2020505154A (ja) 2020-02-20
WO2018140853A8 (en) 2019-07-18
US20190374678A1 (en) 2019-12-12
US10413634B2 (en) 2019-09-17
AU2018212908A1 (en) 2019-08-08
US20230364300A1 (en) 2023-11-16
US20180214602A1 (en) 2018-08-02
JP6942191B2 (ja) 2021-09-29
EP3573674A1 (en) 2019-12-04
CN110290817A (zh) 2019-09-27

Similar Documents

Publication Publication Date Title
US20230364300A1 (en) Transglutaminase treated products
US20250332323A1 (en) Tissue matrices incorporating multiple tissue types
ES2328339T3 (es) Revestimiento inmunoestimulante para dispositivos quirurgicos.
JP4856309B2 (ja) ヒアルロン酸誘導体を含んでいる三次元人工器官及びそれらの調製工程
KR20170003916A (ko) 세포외 기질로부터 유래한 최종 멸균된 하이드로겔의 제조 방법
US20250127862A1 (en) Tissue matrix materials and enzymatic adhesives
Agarwal et al. Comprehensive study related to advancement in biomaterials for medical applications
PT1171175E (pt) O invento refere-se à utilização de um complexa de substâncias activas para a fabricação de peças biológicas, especialmente de órgãos para seres vivos, com os seguintes componentes, diferentes uns dos outros e em cada um dos casos especificamente ada
HK40034646A (en) Transglutaminase treated products
CN106618765A (zh) 一种用于牙科种植体的抗菌肽层
Pardeshi et al. Introduction to Biomaterials in Design of Regenerative Medicine

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant