CN110279511A - It is a kind of to facilitate the sheath that environment maintains in vagina - Google Patents
It is a kind of to facilitate the sheath that environment maintains in vagina Download PDFInfo
- Publication number
- CN110279511A CN110279511A CN201910694011.7A CN201910694011A CN110279511A CN 110279511 A CN110279511 A CN 110279511A CN 201910694011 A CN201910694011 A CN 201910694011A CN 110279511 A CN110279511 A CN 110279511A
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- China
- Prior art keywords
- sheath
- vagina
- lubricant
- lubricating fluid
- bulge loop
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/02—Contraceptive devices; Pessaries; Applicators therefor for use by males
- A61F6/04—Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/02—Contraceptive devices; Pessaries; Applicators therefor for use by males
- A61F6/04—Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
- A61F2006/048—Condoms, sheaths or the like, e.g. combined with devices protecting against contagion with surface protuberances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/10—Materials for lubricating medical devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention provides a kind of sheath for facilitating environment maintenance in vagina, belongs to family planning articles technical field.The sheath includes natural rubber sheath, and screw thread bulge loop is arranged in the sheath surface layer, and several grooves are arranged on the bulge loop；And it is coated in lubricating fluid on sheath bulge loop, lubricating fluid includes bacteriostatic agent, lubricant；The bacteriostatic agent includes Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purified water；And the packaging bag for sealing the natural rubber sheath.Sheath of the present invention is by addition sodium hyaluronate as lubricating fluid, and it joined Gotu Kola P.E, Honegsukle flower P.E, ensuring to be deposited in intracorporal is all substance without any side effects, once during sexual life, vaginal walls have breakage, the centella and honeysuckle Essence for being deposited in intravaginal can rapidly repair, thus the effect maintained environment in vagina.
Description
Technical field
The invention belongs to family planning articles technical fields, and in particular to a kind of to facilitate the contraception that environment maintains in vagina
Set.
Background technique
With the improvement of living standards, the sales volume of sheath also rises year by year.It follows that sheath in the market
Type is increasingly various.In face of panoramic sheath, condom color of today appears, smell is different.This can improve people
To the dislike psychology of condom, increase property attraction.But fragrance, lubricant for wherein adding etc. may result in girl's vagina
Inflammation.
Existing sheath all adds lubricant substantially, and most of sheath is all addition silicone oil and mineral oil as profit
Lubrication prescription, silicone oil and mineral oil are greasy, it is not easy to clean, for a long time using can also cause gynecological disease.In clinic it has also been found that: warp
It is often used that the female vagina of sheath contraception, cervicitis chance of occurrence is with regard to more.Under normal circumstances, vagina also has and some has
Oxygen bacterium and anaerobic bacteria, one balance of formation, one defense mechanism of self-assembling formation have self purification, vaginal fluid between them
Many pathogenic bacteria can be all ejected.However since silicone oil is inorganic matter, and insoluble and water, adsorption capacity is strong, and vagina is
Cyclic annular fold, Long Term Contact silicone oil will affect the metabolism of vagina, and silicone oil accumulation will cause vagina fouling product can not
The problem of discharge；To enabling some harmful germs be difficult to exhaust, when these grease long-term existence are in intravaginal, vagina can be destroyed
In immune system so that germ is easier to breed, this is also frequency one of the reason of being increased using women's gynaecological imflammation of sheath
It is numerous to aggravate gynaecological imflammation using the sheath of silicate-containing oil and mineral oil.
Summary of the invention
The present invention is by providing a kind of sheath for facilitating environment maintenance in vagina, to solve to keep away in the prior art
Pregnant set makees the technical issues of lubricant can generate burden to the vagina of women using silicone oil.
To achieve the above object, the technical solution of the invention is as follows:
A kind of sheath facilitating environment maintenance in vagina, including
Natural rubber sheath, the sheath surface layer are arranged screw thread bulge loop, several grooves are arranged on the bulge loop；
Lubricating fluid, the lubricating fluid are coated on sheath bulge loop, and lubricating fluid includes bacteriostatic agent, lubricant；It is described antibacterial
Agent includes Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purifying
Water；
Sealing bags are used for the natural rubber sheath sealed package；
The amount ratio of the bacteriostatic agent and lubricant is (1.2-2.5): (6-9)；
The careless extract and the amount ratio of Honegsukle flower P.E avenged is (4-7): (1-3)；
The sodium hyaluronate, trehalose, propylene glycol and purified water amount ratio be (1-2): (0.15-0.32): (4-6):
(2-5)。
Preferably, the bacteriostatic agent the preparation method comprises the following steps:
It takes centella and honeysuckle to mix in proportion, is ground into coarse powder, extract reflux twice with ethyl alcohol, 2 hours every time, the
70% ethanol consumption is 12 times of centella and honeysuckle mixture, and second of 65% ethanol consumption is centella and gold and silver
10 times of flower mixture, filtration, merging filtrate are added 0.2% active carbon reflux decoloration in 30-40 minutes, filter, depressurize while hot
The concentration and recovery ethyl alcohol extremely thick medicinal extract without alcohol taste；Thick medicinal extract is added with water to volume and medicinal material amount (2-3): 1 medical fluid, and filtering obtains
Filtrate；AB-8 resin adsorption on filtrate is collected elution fraction, eluent is depressurized dense with 40% ethanol elution of 4 times of column volumes
Be reduced to specific gravity be 1.12-1.14 to obtain the final product.
Preferably, the lubricant the preparation method comprises the following steps:
Sodium hyaluronate, trehalose, propylene glycol are made an addition in purified water in proportion, stirring and dissolving, in the cool sealing storage
It 12-24 hours, sterilizes to obtain the final product.
Preferably, the amount ratio of bacteriostatic agent and lubricant is 2:8.
Preferably, lubricating fluid dosage is 1.2-1.5g in the sheath.
The raw material that the present invention uses has a characteristic that
Centella (Classification system: Centellaasiatica (L.) Urban), also known as Gotu Kola, copper coin grass, membranaceous marshmarigold herb,
For the herb of umbelliferae centella.Gotu Kola P.E shows wide spectrum biological activity for a long time, it is most important that
It is anti-oxidant, anti-inflammatory, antibacterial and anticancer activity.In dermatology, Gotu Kola P.E is for treating minor cut or wound, appreciation scar
Trace, burn, psoriasis etc..Gotu Kola P.E can stimulate fibroblast proliferation and activate SMAD signal transduction path, because
This can increase the generation of I-type collagen and reduce the formation of striae of pregnancy and inflammatory reaction.Gotu Kola P.E can be shown
The hydration levels for increasing cuticula are write, this is mainly related with the triterpene saponin compound in Gotu Kola P.E, asiatic centella triterpenoid
Saponin(e is a kind of hydrophily sugar chain, mainly glucose and rhamnose, can improve epidermal barrier in obstruction layer in conjunction with water
Ability enhances moisture of skin.
Honeysuckle chlorogenic acid rich in plays the role of inhibiting bacteria and diminishing inflammation, antiviral, especially to gram-positive bacteria such as gold
Staphylococcus aureus, streptococcus pneumonia, Streptococcusagalactiae, streptococcus pyogenes effect are stronger.
The beneficial effects of the present invention are:
1. sheath of the present invention joined Gotu Kola P.E, honeysuckle by adding sodium hyaluronate as lubricating fluid
Extract, it is ensured that being deposited in intracorporal is all substance without any side effects, and centella and honeysuckle being capable of anti-inflammatory and right
Wound has repair function, once during sexual life, vaginal walls have breakage, is deposited in the centella and gold and silver anthosin of intravaginal
Magnificent liquid can be repaired rapidly, thus the effect maintained environment in vagina.
2. convex hoop shape screw thread is arranged in sheath surface layer of the present invention, and groove is arranged on screw thread, further groove can be deposited
Lubricating fluid is stored up, the lubricating action of sheath can be enhanced.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of sheath of the present invention.
Fig. 2 is the structural schematic diagram of bulge loop of the present invention.
In figure: 1- sheath；2- bulge loop；3- groove.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts it is all its
His embodiment, shall fall within the protection scope of the present invention.
It in addition, the technical solution between each embodiment of the present invention can be combined with each other, but must be general with this field
Based on logical technical staff can be realized, it will be understood that when the combination of technical solution appearance is conflicting or cannot achieve this
The combination of technical solution is not present, also not the present invention claims protection scope within.
It is a kind of to facilitate the sheath that environment maintains in vagina, the packaging including sealing；Day in the packaging
Right rubber condoms；Screw thread bulge loop is arranged in the sheath surface layer, and several grooves are arranged on the bulge loop；And in the packet
In dress and coated in the lubricating fluid on sheath bulge loop, the lubricating fluid includes bacteriostatic agent, lubricant；The bacteriostatic agent includes
Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purified water；It is described
The amount ratio of bacteriostatic agent and lubricant is (1.2-2.5): (6-9)；The amount ratio for avenging careless extract and Honegsukle flower P.E
For (4-7): (1-3)；The sodium hyaluronate, trehalose, propylene glycol and purified water amount ratio be (1-2): (0.15-0.32):
(4-6): (2-5).
Referring to Fig. 1,1 surface layer of sheath sheath is arranged screw thread bulge loop 2, several grooves 3 is arranged on the bulge loop.This hair
It is bright that experience effect can be enhanced by the way that screw thread bulge loop is arranged on sheath surface layer, while groove is set on bulge loop, it can be to profit
Synovia enhances the lubricant effect of sheath into storage.
Embodiment 1
It is a kind of to facilitate the sheath that environment maintains in vagina, the packaging bag including sealing；In the packaging bag
Natural rubber sheath；Screw thread bulge loop is arranged in the sheath surface layer, and several grooves are arranged on the bulge loop；And institute
The lubricating fluid in packaging and being coated on sheath bulge loop is stated, the lubricating fluid includes bacteriostatic agent, lubricant；The bacteriostatic agent
Including Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purified water；
The amount ratio of the bacteriostatic agent and lubricant is 2:8；The careless extract and the amount ratio of Honegsukle flower P.E avenged is 4:2；Institute
The amount ratio for stating sodium hyaluronate, trehalose, propylene glycol and purified water is 1:0.25:4:5；Lubricating fluid dosage is in sheath
1.2g。
The bacteriostatic agent the preparation method comprises the following steps: centella and honeysuckle is taken to mix in proportion, be ground into coarse powder, mentioned with ethyl alcohol
Fetch stream twice, 2 hours every time, 70% ethanol consumption was 12 times of centella and honeysuckle mixture for the first time, for the second time
65% ethanol consumption is 10 times of centella and honeysuckle mixture, is filtered, merging filtrate, and 0.2% active carbon reflux is added
It decolourizes within 40 minutes, filters while hot, recycling ethyl alcohol is concentrated under reduced pressure to the thick medicinal extract without alcohol taste；Thick medicinal extract is added with water to volume and medicinal material
The medical fluid of 2.5:1 is measured, filtering obtains filtrate；AB-8 resin adsorption on filtrate, with 40% ethanol elution of 4 times of column volumes, collection is washed
De- part, it is 1.14 that eluent, which is concentrated under reduced pressure into specific gravity, to obtain the final product.
The lubricant the preparation method comprises the following steps: sodium hyaluronate, trehalose, propylene glycol are made an addition in purified water in proportion, stir
Mix dissolution, sealing storage 16 hours, sterilizes in the cool to obtain the final product.
Bacteriostatic agent obtained and lubricant are mixed in proportion up to lubricating fluid.
Embodiment 2
It is a kind of to facilitate the sheath that environment maintains in vagina, the packaging including sealing；Day in the packaging
Right rubber condoms；Screw thread bulge loop is arranged in the sheath surface layer, and several grooves are arranged on the bulge loop；And in the packet
In dress and coated in the lubricating fluid on sheath bulge loop, the lubricating fluid includes bacteriostatic agent, lubricant；The bacteriostatic agent includes
Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purified water；It is described
The amount ratio of bacteriostatic agent and lubricant is 2.5:6；The careless extract and the amount ratio of Honegsukle flower P.E avenged is 5:3；It is described
Sodium hyaluronate, trehalose, propylene glycol and purified water amount ratio be 1.5:0.32:5:2；Lubricating fluid dosage is in sheath
1.3g。
The bacteriostatic agent the preparation method comprises the following steps: centella and honeysuckle is taken to mix in proportion, be ground into coarse powder, mentioned with ethyl alcohol
Fetch stream twice, 2 hours every time, 70% ethanol consumption was 12 times of centella and honeysuckle mixture for the first time, for the second time
65% ethanol consumption is 10 times of centella and honeysuckle mixture, is filtered, merging filtrate, and 0.2% active carbon reflux is added
It decolourizes within 30 minutes, filters while hot, recycling ethyl alcohol is concentrated under reduced pressure to the thick medicinal extract without alcohol taste；Thick medicinal extract is added with water to volume and medicinal material
The medical fluid of 3:1 is measured, filtering obtains filtrate；AB-8 resin adsorption on filtrate collects elution with 40% ethanol elution of 4 times of column volumes
Part, it is 1.12 that eluent, which is concentrated under reduced pressure into specific gravity, to obtain the final product.
The lubricant the preparation method comprises the following steps: sodium hyaluronate, trehalose, propylene glycol are made an addition in purified water in proportion, stir
Mix dissolution, sealing storage 24 hours, sterilizes in the cool to obtain the final product.
Bacteriostatic agent obtained and lubricant are mixed in proportion up to lubricating fluid.
Embodiment 3
It is a kind of to facilitate the sheath that environment maintains in vagina, the packaging including sealing；Day in the packaging
Right rubber condoms；Screw thread bulge loop is arranged in the sheath surface layer, and several grooves are arranged on the bulge loop；And in the packet
In dress and coated in the lubricating fluid on sheath bulge loop, the lubricating fluid includes bacteriostatic agent, lubricant；The bacteriostatic agent includes
Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purified water；It is described
The amount ratio of bacteriostatic agent and lubricant is 1.2:7；The careless extract and the amount ratio of Honegsukle flower P.E avenged is 7:1；It is described
Sodium hyaluronate, trehalose, propylene glycol and purified water amount ratio be 2:0.15:6:4；Lubricating fluid dosage is 1.5g in sheath.
The bacteriostatic agent the preparation method comprises the following steps: centella and honeysuckle is taken to mix in proportion, be ground into coarse powder, mentioned with ethyl alcohol
Fetch stream twice, 2 hours every time, 70% ethanol consumption was 12 times of centella and honeysuckle mixture for the first time, for the second time
65% ethanol consumption is 10 times of centella and honeysuckle mixture, is filtered, merging filtrate, and 0.2% active carbon reflux is added
It decolourizes within 35 minutes, filters while hot, recycling ethyl alcohol is concentrated under reduced pressure to the thick medicinal extract without alcohol taste；Thick medicinal extract is added with water to volume and medicinal material
The medical fluid of 2:1 is measured, filtering obtains filtrate；AB-8 resin adsorption on filtrate collects elution with 40% ethanol elution of 4 times of column volumes
Part, it is 1.13 that eluent, which is concentrated under reduced pressure into specific gravity, to obtain the final product.
The lubricant the preparation method comprises the following steps: sodium hyaluronate, trehalose, propylene glycol are made an addition in purified water in proportion, stir
Mix dissolution, sealing storage 12 hours, sterilizes in the cool to obtain the final product.
Bacteriostatic agent obtained and lubricant are mixed in proportion up to lubricating fluid.
The above description is only an embodiment of the present invention, is not intended to limit the scope of the invention, all to utilize this hair
Equivalent structure or equivalent flow shift made by bright specification and accompanying drawing content is applied directly or indirectly in other relevant skills
Art field, is included within the scope of the present invention.
Claims (5)
1. a kind of facilitate the sheath that environment maintains in vagina, which is characterized in that including
Natural rubber sheath, the sheath surface layer are arranged screw thread bulge loop, several grooves are arranged on the bulge loop；
Lubricating fluid, the lubricating fluid are coated on sheath bulge loop, and lubricating fluid includes bacteriostatic agent, lubricant；The bacteriostatic agent packet
Include Gotu Kola P.E and Honegsukle flower P.E；The lubricant includes sodium hyaluronate, trehalose, propylene glycol and purified water；
Sealing bags are used for the natural rubber sheath sealed package；
The amount ratio of the bacteriostatic agent and lubricant is (1.2-2.5): (6-9)；
The careless extract and the amount ratio of Honegsukle flower P.E avenged is (4-7): (1-3)；
The sodium hyaluronate, trehalose, propylene glycol and purified water amount ratio be (1-2): (0.15-0.32): (4-6): (2-
5)。
2. according to claim 1 facilitate the sheath that environment maintains in vagina, which is characterized in that described antibacterial
Agent the preparation method comprises the following steps:
It takes centella and honeysuckle to mix in proportion, is ground into coarse powder, extract reflux twice with ethyl alcohol, 2 hours every time, for the first time
70% ethanol consumption is 12 times of centella and honeysuckle mixture, and second of 65% ethanol consumption is that centella and honeysuckle are mixed
10 times for closing object, filtration, merging filtrate are added 0.2% active carbon reflux decoloration in 30-40 minutes, filter, be concentrated under reduced pressure while hot
Ethyl alcohol is recycled to the thick medicinal extract without alcohol taste；Thick medicinal extract is added with water to volume and medicinal material amount (2-3): 1 medical fluid, and filtering obtains filtrate；
AB-8 resin adsorption on filtrate is collected elution fraction, eluent is concentrated under reduced pressure into 40% ethanol elution of 4 times of column volumes
Specific gravity be 1.12-1.14 to obtain the final product.
3. according to claim 1 facilitate the sheath that environment maintains in vagina, which is characterized in that the lubrication
Agent the preparation method comprises the following steps:
Sodium hyaluronate, trehalose, propylene glycol are made an addition in purified water in proportion, stirring and dissolving, in the cool sealing storage 12-24
Hour, it sterilizes to obtain the final product.
4. the sheath according to claim 1 for facilitating environment in vagina and maintaining, which is characterized in that bacteriostatic agent and
The amount ratio of lubricant is 2:8.
5. according to claim 4 facilitate the sheath that environment maintains in vagina, which is characterized in that the contraception
Lubricating fluid dosage is 1.2-1.5g in set.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910694011.7A CN110279511A (en) | 2019-07-30 | 2019-07-30 | It is a kind of to facilitate the sheath that environment maintains in vagina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910694011.7A CN110279511A (en) | 2019-07-30 | 2019-07-30 | It is a kind of to facilitate the sheath that environment maintains in vagina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110279511A true CN110279511A (en) | 2019-09-27 |
Family
ID=68024307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910694011.7A Pending CN110279511A (en) | 2019-07-30 | 2019-07-30 | It is a kind of to facilitate the sheath that environment maintains in vagina |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110279511A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112006832A (en) * | 2020-09-25 | 2020-12-01 | 郑闪 | Condom |
| GB2604189A (en) * | 2021-02-10 | 2022-08-31 | Reckitt Benckiser Health Ltd | Packaged lubricated condom |
| CN116474176A (en) * | 2023-03-21 | 2023-07-25 | 宁波汉科医疗器械有限公司 | Lubricating fluid suitable for natural cavity and tract of human body and application thereof |
Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN2461512Y (en) * | 2001-01-05 | 2001-11-28 | 刘家全 | Venereal disease preventing condom |
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| CN1660130A (en) * | 2004-12-20 | 2005-08-31 | 凌沛学 | Human body lubricant of containing fucose and hyaluronic acid, and its prepn. method |
| CN101396384A (en) * | 2007-09-28 | 2009-04-01 | 天津天士力现代中药资源有限公司 | Asiatic centella extract and preparation methode thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112006832A (en) * | 2020-09-25 | 2020-12-01 | 郑闪 | Condom |
| GB2604189A (en) * | 2021-02-10 | 2022-08-31 | Reckitt Benckiser Health Ltd | Packaged lubricated condom |
| CN116474176A (en) * | 2023-03-21 | 2023-07-25 | 宁波汉科医疗器械有限公司 | Lubricating fluid suitable for natural cavity and tract of human body and application thereof |
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