KR101724147B1 - Cosmetic composition having anti-itching effect containing crude drug extracts - Google Patents

Abstract

A cosmetic composition for suppressing and alleviating itching, comprising an extract of a herbal medicine comprising a centilla extract, a golden extract, a chamomile extract, a magnolia bark extract, a green tea extract, a royal jelly extract and a buttercage extract as active ingredients, The present invention relates to a cosmetic composition for suppressing and alleviating itching and it is effective for improving sensitive skin by containing herbal medicine extracts having the effects of soothing, itching inhibition and improvement of skin, antibacterial, anti-inflammatory, antioxidant and anti- And it is characterized by hypoallergenic properties to prevent allergic reactions and to alleviate or ameliorate skin troubles such as itching, inflammation, erythema and skin damage.

Description

[0001] Cosmetic compositions containing anti-itching extract containing crude drug extracts [

The present invention relates to a cosmetic composition for suppressing and alleviating itching comprising an extract of herbal medicine, and more particularly to a cosmetic composition containing a herbal extract of various kinds useful for skin improvement, as an active ingredient, to stabilize sensitive, irritating or reactive skin, To a cosmetic composition which relieves hot sensation and inflammation to effectively improve sensitive skin such as atopic skin and alleviates or prevents irritation to the skin.

It is well known that certain skin types are more sensitive than others, and these skin are generally referred to as sensitive skin, which is a skin that exhibits better contact stimuli or Allergy response than the average group .

Although the cause of the sensitive skin is not clearly known, it is generally known to be caused by external influences such as cosmetics, psychological / physical stress, air pollution and other environmental substances.

Symptoms of the sensitive skin include visible reactions such as erythema, skin dryness, stinging, itching (pruritus) and inflammation, and such sensitive skin holders are increasingly on the rise.

An example of such a sensitive skin is skin with atopic dermatitis, that is, atopic skin. Atopy means a strange, strange, strange, unfamiliar, out of place, Abnormal reaction, oddity, etc.

Atopic dermatitis is a skin inflammation that occurs when contact dermatitis is caused by exposure to a substance that irritates the skin or causes an allergic reaction. Many types of natural or artificial chemicals present around us promote contact dermatitis Such as soaps, cleansers, detergents, precious metals, perfumes, industrial solvents, cosmetics, fabric finishes, shampoos or antibiotic ointments.

Symptoms of atopic dermatitis accompany skin eruptions, skin edema, blisters, ulcers and severe itching. If the treatment for the atopic dermatitis is not performed, the skin is continuously exposed to a substance promoting the skin reaction, so that the contact dermatitis becomes chronic, the skin thickens and peels off due to chronic contact dermatitis, Loss of hair also occurs.

The atopic dermatitis causes 0.5 to 1% of the whole population and 5 to 10% of the children suffering from the atopic dermatitis. The onset period of the atopic symptoms is generally 2 to 6 months after birth, 85% appear within five years of age.

The atopic dermatitis is usually known to be a short-lived disease at a young age, but 50% of the patients disappear within two months, 25% continue to adolescence, and the remaining 25% continue to disappear even if they become adults.

In recent years, there has been an increasing demand for a composition for skin external application such as a human body cleanser, a hair shampoo, a hair conditioner, etc., which can be safely used without being irritated by sensitive or extremely sensitive skin holders such as atopic skin. In addition, Various studies have been actively conducted on cosmetics and external skin products that improve the condition.

The cosmetic composition for the above-mentioned atopic skin and (sensitive) skin can be used as an anti-soothing agent that suppresses or alleviates the itching without causing itching and skin irritation, has an anti-inflammatory effect, Bacteria-suppressing bacteria-suppressing effect, moisturizing and protecting skin barrier, and restoring skin protection effect.

However, there have been studies and research results of academia claiming that chemical preservatives (parabens, phenoxyethanol, diazolidinyl urea) used in common cosmetic formulations damage human DNA, and there are cases where atopic and extreme sensitive skin cause sensitive itching Replacement is required.

In addition, the mineral oil (Petrolatum) used in common cosmetic formulations has a strong skin oil film and inhibits skin respiration, resulting in erythema, itching, and irritation of the skin with extremely sensitive atopic skin. Is required.

In addition, antimicrobial agents (Mycin) and antimicrobials (antimicrobials) that replace steroids and antifungal agents, which are resistant to inflammation and inhibition of bacterial growth in atopic skin, (Polyethylene glycol), dibutylhydroxytoluene (DHT), butylhydroxy anisole (BHA), avobenzene, oxybenzone, isopropyl alcohol, synthetic surfactants, etc., which are given skin side effects and human health risks, A manufacturing technique which is not used from the step of preparing the composition to the step of preparing the composition is required.

In order to repair skin barrier damage, it is required to develop a composition containing ingredients that promote cell regeneration beyond the step of protecting skin damaged by lipids (ceramides), oil, plant butter, and the like.

SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide a cosmetic composition for suppressing and alleviating itching, which comprises a herbal medicine extract suitable for sensitive skin such as atopic skin.

In order to solve the above problems, a cosmetic composition for suppressing and alleviating itching is characterized in that it comprises, as an active ingredient, a herbal medicine extract comprising a centilla extract, a golden extract, a chamomile extract, a magnolia bark extract, a green tea extract, And a cosmetic composition for suppressing and alleviating itching.

In addition, in the present invention, the golden extract contains 1.5 to 2.5% by weight based on the total weight of the cosmetic composition for suppressing and alleviating itching, and the centipede extract, chamomile extract, Magnolia bark extract, green tea extract, 0.5 to 2.5% by weight based on the total weight of the cosmetic composition.

In one embodiment of the present invention, the buttercups extract is a fermented extract obtained by fermenting buttercups.

The present invention also provides a cosmetic composition for suppressing and alleviating itching, characterized in that the herbal medicine extract which is an active ingredient of the cosmetic composition for suppressing and alleviating the itch is extracted by ultrasonic extraction.

In the present invention, at least one formulation agent selected from the group consisting of argan oil, oilseed rape seed oil and shea butter is added to a cosmetic composition for suppressing and alleviating itching, which contains the herbal medicine extract as an active ingredient, The present invention also provides a cosmetic composition for suppressing and alleviating itching.

In the present invention, the argan oil content is 5 to 20% by weight, the oilseed rape seed oil is 5 to 10% by weight and the shea butter is 5 to 10% by weight based on the total weight of the cosmetic composition for suppressing and alleviating itching, A cosmetic composition for inhibiting and relieving itching.

In the present invention, the cosmetic composition for suppressing and alleviating the itch may be at least one selected from the group consisting of lotion, lotion, nutritional cream, massage cream, essence, gel, serum, pack, powder, ointment for external use, And a cosmetic composition for suppressing and alleviating itching.

The cosmetic composition for suppressing and alleviating itching comprising the herbal medicine extract according to the present invention contains herbal medicine extracts having an effect such as skin soothing, itching inhibition and improvement, antibacterial, anti-inflammatory, antioxidant, anti-atopic , It is effective for the improvement of sensitive skin, and it can prevent the allergic reaction due to hypoallergenic to the skin and can alleviate or improve the skin troubles such as itching, inflammation, erythema and skin damage.

The following embodiments are provided by way of example so that those skilled in the art can fully understand the spirit of the present invention. Therefore, the present invention is not limited to the embodiments described below, but may be embodied in other forms.

The present invention is a cosmetic composition for exfoliation comprising an herbal medicine extract as an active ingredient. Specific examples of the present invention will be described in detail below.

The composition according to the present invention contains, as an active ingredient, a herbal medicine extract comprising a centipedial extract, a golden extract, a chamomile extract, a magnolia bark extract, a green tea extract, a royal jelly extract, and a dropwort extract. In an embodiment of the present invention, the buttercups extract may be an extract obtained by extracting buttercups with ultrasonic waves or hot water, or may be an extracted fermentation extract after naturally fermenting buttercups.

Asiatic Pennywort is a perennial plant of dicotyledonous plant, dicotyledonous plant, phylloquinomycetes, and periwinkle, which is distributed mainly in Korea, Japan and China. It lives in a humid region and is used as medicinal product in India.

Gold (Skullcap) is a perennial plant of the dicotyledonous monocotyledonous plant. It grows in mountainous meadows, is about 20 ~ 60cm in height and is grown as a medicinal plant. In addition, the above-mentioned gold grows on the abandonment with several hairs, the branches are split, the leaves are opposite, the bosom is flat, and the edges are flat. In one room, the above-mentioned gold is used as fever, diuretic, branch, insect, and anti-inflammatory agent.

Chamomile (Chamomile) is a grass belonging to the dicotyledonous plant. It is sometimes referred to as Camomile, Chamomile, or Camomile. The country of origin is in England, but now it is found all over the world. Chamomile also helps to alleviate symptoms, relieve symptoms, and act as an antimicrobial agent by using cold chamomile tea to treat skin inflammation caused by fleas, contact allergies and various bacterial and fungal infections.

Magnolia uses the magnolia bud as a medicine called ginseng. The name God is a name that is said to be a little spicy. From the past, gods are known to be the best medicine for nodules, and all the seeds, roots, bark and leaves are used in medicine. The Shin has an efficacy that penetrates the enchantments and pierces the clogged areas. It cleanses the headache, sinusitis, nasal congestion, and toothache, eliminates the cold and cold of the stomach, cleanses the head, Lt; / RTI > And when the god is made into a cream and applied to the face, the spots, freckles, acne disappear and the face becomes smooth and glows. Shin also brightens the eyes, heals the thirsty symptoms of the cold, and eliminates the symptoms of fever and itchy sores. Magnolia bark is known for its flavor and cold properties. It treats many diseases caused by alcohol and has good effect on eczema, swelling, swelling and various skin diseases. Magnolia bark enhances eyesight and hearing, eliminates bad smell, makes urine come out well, and is very effective for back pain, headache, sore throat, rhinitis, sinusitis.

Green tea (culture: green tea, kanji: 綠茶, Japanese: り ょ く ち ゃ) refers to water that has not been fermented, dried tea leaves to leave the blue light intact, or tea leaves. Vitamin A and tannin in the green tea keeps the skin healthy, vitamin C ingredient is 5 to 8 times more than lemon, melanin pigment is suppressed and makes the skin white. Also, the soothing effect of the skin, the moisturizing effect and the delayed aging of the skin, and the fragrance that comes out of the green tea releases the mind and body fatigue. Green tea extract protects the skin from various harmful factors, so it has the effect of making the skin cleaner and healthier.

Mandarin is the most common of the mandarins and is the origin of the Malay Peninsula and is mainly grown in tropical and subtropical regions. Saponin, sapotoxin, saponin, etc., are contained in the citrus tree, so that it absorbs nutrients and facilitates metabolism. Especially, it is effective in improving dermatitis because it has immune and anti-inflammatory action. In addition, the bark of the royal bark has a detoxifying effect because it has a skin cleansing function.

Minari is a perennial herb that grows in the hills of Korea, and is commonly found in wetlands and wetlands near water. They are cultivated wild in Jeju, Jeonnam, Jeonbuk, Gyeongbuk, Chungnam, Chungbuk, and Gangwon provinces. The buttercup is an alkaline plant rich in various vitamins and minerals and fiber.

The composition of the present invention can be obtained by mixing the herbal medicine extracts including the centilla extract, golden extract, chamomile extract, Magnolia bark extract, green tea extract, royal jelly extract, and dropwort extract at various weight ratios. More specifically, the composition of the present invention contains 0.5 to 2.5% by weight of Centella asiatica extract, Chamomile extract, Magnolia bark extract, Green tea extract, Mandarin extract and Millipore extract, respectively, and the gold extract may contain 1.5 to 2.5% by weight However, the scope of the present invention is not limited thereto.

In addition, the composition may be formulated by one or more formulating agents selected from the group consisting of argan oil, oilseed rape seed oil, and shea butter. Argan oil, oilseed rape seed oil, and shea butter are vegetable oils and can be formulated into various formulations such as liquid solutions, creams, lotions and the like depending on their contents. Since the argan oil, the oilseed rape seed oil and the shear butter can be applied to the composition according to the present invention by using a known commercial product, the description of the specific production method is omitted. Among them, the argan oil is classified into the European organic certification body Ecocert Ecocert) is known to be produced by the cold pressing method. It is effective for prevention of aging / wrinkle, atopic skin, skin elasticity, skin inflammation, etc., and various products for basic cosmetics, makeup, hair . In addition, the oilseed rape seed oil is produced by the same process by a known method of producing sesame oil to prevent destruction of an active ingredient, that is, a known low-temperature squeeze method. The sheared butter is a fruit of a shea tree Is mainly used as a skin moisturizing agent and softening agent. It is also used for food, and it is known that it has antioxidant and anti-inflammatory effect in addition to skin moisturizing and regenerating effect. The sheer butter also has an ultraviolet shielding effect. The ultraviolet shielding effect is about a sun protection factor (SPF) of about 6, and it stimulates the capillary blood vessels to make hair and scalp thicker, . When the weight ratio of the argan oil and the oil seed oil is 10% by weight or more based on the total weight of the composition, the composition may be formulated into a cream, 5-10% by weight may be formulated into lotion, % Or less, it can be formulated into a liquid solution (skin). In addition, the formulations may be formulated into various forms such as lotions, nutritional creams, massage creams, essences, gels, serums, packs, powders, ointments for external use, sprays, suspensions, emulsions, sprays or cosmetics depending on the composition ratio. The argan oil is contained in an amount of 0 to 20% by weight, more specifically 5 to 20% by weight, based on the total weight of the composition, 0 to 10% by weight, more specifically 5 to 10% , And the shear butter is contained in an amount of 0 to 10 wt%, more specifically 5 to 10 wt%, to form a composition according to a specific embodiment of the present invention.

 The content of each component constituting the composition of the present invention is not limited to that described above and it is possible to produce a composition effective for exfoliation which does not impair low stimulation and skin moisturizing ability even if the contents of the components are changed. Hereinafter, the present invention will be described in more detail by way of examples. However, the following examples illustrate the present invention and the contents of the present invention are not limited to the following examples.

Preparation Example 1: Preparation of herbal extracts

The herbal medicine extracts including the centilla extract, golden extract, chamomile extract, Magnolia bark extract, green tea extract, royal jelly extract, and parsley extract can be prepared by various known extraction methods. In this embodiment, An example is given.

In general, ultrasonic waves have a higher frequency than the human audible frequency range, and the ultrasonic extraction method can complete the extraction in a very short time compared with general solvent extraction, and the extraction time is shortened by about 10 times as compared with the supercritical extraction (2), 149-152 (2000). Kim WI, KW (2000). &Quot; Ultrasonic energy effects on squalene extraction from amaranth seed ". Applied Chemistry. Chung, SB Lee, IK Hong and KA Park, "Ultrasonic energy effects on solvent extraction from amaranth seed oil", J. Korean Ind. Eng Chem. 12 (3), 307-311 (2001))

Hereinafter, a method for extracting the in-line extract will be described. Ultrasonic waves having a wavelength of 35 to 45 kHz, in particular ultrasonic waves having a wavelength of 40 kHz, are used, and the centistallium extract is extracted with an ultrasonic wave having an output of about 300 to 500 Watt. 2 parts by weight of the cinnabar raw materials and an extraction solvent (68 parts by weight of purified water and 30 parts by weight of 1,3-butylene glycol) were put into a known ultrasonic wave extractor and ultrasonically operated to extract the mixture at 40 to 50 ° C for about 2 hours To obtain the primary extract. Butyleneglycol is a large organic alcohol, which has the effect of pulling moisture, so it exhibits a moisturizing effect of maintaining the moisture of the skin and is a safe solvent having no skin irritation. More specifically, ultrasound is applied at an output of about 300 Watt at about 40 캜 for 1 hour, then the ultrasound waves are applied for 1 hour at an output of 500 Watt at a temperature of 50 캜 to cool the first centella cochilla extract to room temperature, Remove the raw materials. The primary extract was filtered through a filter paper having a pore size of 0.4 to 0.8 탆 to obtain a liquid pomfret buds extract.

The manufacturing process of the above-mentioned gold extract, chamomile extract, magnolia bark extract, green tea extract, royal jelly extract and buttercup extract (including buttercage fermentation extract) is also obtained by the ultrasonic extraction method using the same amount of raw materials in the same manner as the above- .

Meanwhile, the argan oil was used as a raw material for importing morganosan (trademark: www.fairetrade.net), Organic Pure Argan Oil-Moroco acid) Marionel, product name: Premium Shea Butter from France). The oilseed rape seed oil is obtained by a low-temperature squeezing method, and more specifically, can be obtained by milking 100 g of oilseed rape seeds at room temperature to 40 캜.

Preparation Example 2: Preparation of the composition according to the present invention

First, the above-mentioned gold extract is mixed with each of all other components except for the above-mentioned gold extract, so that 2 wt% of the above-mentioned gold extract is contained in the whole of the mixture solution (for example, the mixture of the extract and the gold extract).

The purified water was heated to 100 degrees Celsius, cooled to 50 degrees C, and mixed with the gold extract and the purified water to make the gold extract 2 wt%.

Next, the composition according to the present invention is prepared by mixing all constituents, stirring / mixing with a stirrer, and then cooling to room temperature.

In the present invention, the remaining herbal medicine extract components except for the golden extract are mixed at almost the same weight ratio so that each component exhibits uniform efficacy. When the amount of the gold extract is more than 2.5% by weight based on the total weight, anticorrosion and antioxidant power are better, The cost is increased, and if it is less than 1.5% by weight, the antifogging and antioxidant power may be problematic. On the other hand, it is generally desirable that no thickeners and metal ion sequestering agents or pH adjusters added to the cosmetic composition are added.

As described above, the present invention includes various herbal medicine extracts useful for skin improvement as an active ingredient, thereby stabilizing sensitive, irritating or reactive skin, alleviating itching, hot sensation and inflammation, effectively improving sensitive skin such as atopic skin, ≪ / RTI > was prepared with the examples in Table 1 below. ≪ tb > < TABLE >

Constituent Example 1 (unit% by weight) Example 2 (unit weight%) Centipede extract One 2 Golden extract 2 2 Chamomile extract One 2 Magnolia bark extract One 2 Green tea extract One 2 Royal jelly extract One 2 Manila extract One 2 Argan oil 15 15 Oil seed oil 8 8 Sheer butter 8 8 Purified water Balance Balance

Experimental Example

1. Atopic skin improvement

The compositions prepared by blending the composition ratios shown in Table 1 above were evaluated for improvement effect and sensation of use on atopic skin and extremely sensitive skin. The evaluation method was as follows. The results obtained by dividing the evaluation score of the atopic child and 20 adult men and women using the cosmetic composition of the present invention for two weeks were divided by 10, and the results are shown in Table 2 below.

Evaluation items Example 1 Example 2 Skin irritant 5 4.7 Itching inhibition 4.3 5 Redness and inflammation inhibition 4.3 5 Moisturizing effect 5 5 Total Atopy Suppression 4.6 4.7 Evaluation Criteria 5: Very good, 4: Good, 3: Fair.

According to the contents of the above [Table 2], the cosmetic composition for suppressing and alleviating itching comprising the herbal medicine extract of the present invention is excellent in suppressing and alleviating symptoms of atopic skin without stimulating the atypical skin, .

2. Evaluation of the antimicrobial activity of the finished product

The antimicrobial activity was tested by direct smear test and visual inspection. The test strains were S. aureus, E. coli, P. aeruginosa, Candida albicans (C. albicans, and A. fumigatus were used.

For the test method, the bacterial solution cultured in YM medium for 24 hours was adjusted to the concentration of # 0.5 McFarland standard, and the cultured broth was evenly plated on each plate medium, dried for 3 to 5 minutes, Was placed on the culture medium and completely adhered thereto. Then, the test was performed on days 1, 3, and 7, and the results are shown in Table 3 below.

(Unit: number) Test strain 0 days 1 day 3 days 7 days Staphylococcus aureus 2.2 * 10 ⁷ 0 0 0 Escherichia coli 2.2 * 10 ⁷ 0 0 0 P. aeruginosa 2.2 * 10 ⁷ 10 0 0 Candida albicans 2.2 * 10 ⁷ 10 0 0 Yeast mold 1.8 * 10 ⁷ 0 0 0

According to the contents of the above Table 3, it can be seen that the composition according to the present invention exhibits a strong antibacterial effect against the five test strains commonly used for testing the antibacterial activity of cosmetics. In particular, the antimicrobial effect is maintained for more than one week, and it is found that there is an excellent effect for alleviating symptoms of skin infection caused by skin scratching and inhibiting bacterial growth.

The foregoing description is merely illustrative of the technical idea of the present invention, and various changes and modifications may be made by those skilled in the art without departing from the essential characteristics of the present invention. Therefore, the embodiments disclosed in the present invention are intended to illustrate rather than limit the scope of the present invention, and the scope of the technical idea of the present invention is not limited by these embodiments. The scope of protection of the present invention should be construed according to the following claims, and all technical ideas within the scope of equivalents should be construed as falling within the scope of the present invention.

It is also to be understood that the terms such as " comprises, "" comprising," or "having ", as used herein, mean that a component can be implanted unless specifically stated to the contrary. But should be construed as including other elements. All terms, including technical and scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, unless otherwise defined. Commonly used terms, such as predefined terms, should be interpreted to be consistent with the contextual meanings of the related art, and are not to be construed as ideal or overly formal, unless expressly defined to the contrary.

Claims (7)

A cosmetic composition for suppressing and alleviating itching, which comprises at least one of centilla extract, golden extract, chamomile extract, magnolia bark extract, green tea extract and royal jelly extract; And herbal extracts comprising an extract of the extract, as an active ingredient and containing the remaining purified water,
Wherein the gold extract contains 1.5 to 2.5 wt%, and the centistallium extract, chamomile extract, magnolia bark extract, green tea extract, royal jelly extract, and corydalis extract each contain 0.5 to 2.5 wt% ≪ / RTI >
delete The method according to claim 1,
Wherein the buttercup extract is a fermented extract extracted from fermented buttercups.
The method according to claim 1,
Wherein the herbal medicine extract as an active ingredient of the cosmetic composition for suppressing and alleviating the itch is extracted by ultrasonic extraction method.
The method according to claim 1,
The cosmetic composition for suppressing and alleviating itching which contains the herbal medicine extract as an active ingredient is further added with at least one formulating agent selected from the group consisting of argan oil, oil seed oil, and shea butter, Wherein the cosmetic composition is a cosmetic composition for suppressing and alleviating itching.
6. The method of claim 5,
Characterized in that the argan oil contains 5 to 20% by weight, the oilseed rape seed oil is 5 to 10% by weight and the shea butter is 5 to 10% by weight based on the total weight of the cosmetic composition for suppressing and alleviating itching Gt; cosmetic < / RTI > composition for inhibiting and alleviating itching.
7. The method according to any one of claims 1 to 6,
Characterized in that the formulation of the cosmetic composition for suppressing and alleviating the itch is a lotion, lotion, nutritional cream, massage cream, essence, gel, serum, pack, powder, ointment for external use, Gt; cosmetic < / RTI > composition for inhibiting and alleviating itching.