CN110267971B - 免疫调节剂 - Google Patents
免疫调节剂 Download PDFInfo
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- CN110267971B CN110267971B CN201780082480.2A CN201780082480A CN110267971B CN 110267971 B CN110267971 B CN 110267971B CN 201780082480 A CN201780082480 A CN 201780082480A CN 110267971 B CN110267971 B CN 110267971B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662418352P | 2016-11-07 | 2016-11-07 | |
| US62/418352 | 2016-11-07 | ||
| PCT/US2017/060107 WO2018085750A2 (en) | 2016-11-07 | 2017-11-06 | Immunomodulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110267971A CN110267971A (zh) | 2019-09-20 |
| CN110267971B true CN110267971B (zh) | 2023-12-19 |
Family
ID=60574708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780082480.2A Active CN110267971B (zh) | 2016-11-07 | 2017-11-06 | 免疫调节剂 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10988507B2 (enExample) |
| EP (1) | EP3535280B1 (enExample) |
| JP (1) | JP7085545B2 (enExample) |
| KR (1) | KR102526034B1 (enExample) |
| CN (1) | CN110267971B (enExample) |
| ES (1) | ES2910832T3 (enExample) |
| WO (1) | WO2018085750A2 (enExample) |
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| US11203610B2 (en) | 2017-12-20 | 2021-12-21 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| CN111788204B (zh) | 2018-02-26 | 2023-05-05 | 吉利德科学公司 | 作为hbv复制抑制剂的取代吡咯嗪化合物 |
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| TW202005654A (zh) | 2018-04-06 | 2020-02-01 | 捷克科學院有機化學與生物化學研究所 | 2,2,─環二核苷酸 |
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| US9809625B2 (en) * | 2015-03-18 | 2017-11-07 | Bristol-Myers Squibb Company | Immunomodulators |
| US10143746B2 (en) * | 2016-03-04 | 2018-12-04 | Bristol-Myers Squibb Company | Immunomodulators |
| US10358463B2 (en) * | 2016-04-05 | 2019-07-23 | Bristol-Myers Squibb Company | Immunomodulators |
| CN110997698B (zh) | 2017-06-23 | 2023-12-26 | 百时美施贵宝公司 | 充当pd-1拮抗剂的免疫调节剂 |
| WO2019070643A1 (en) | 2017-10-03 | 2019-04-11 | Bristol-Myers Squibb Company | IMMUNOMODULATORS |
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| CN105209479A (zh) * | 2013-03-15 | 2015-12-30 | 百时美施贵宝公司 | Pd-1/pd-l1和cd80(b7-1)/pd-l1蛋白质/蛋白质相互作用的大环抑制剂 |
| WO2016057624A1 (en) * | 2014-10-10 | 2016-04-14 | Bristol-Myers Squibb Company | Immunomodulators |
| WO2016100285A1 (en) * | 2014-12-18 | 2016-06-23 | Bristol-Myers Squibb Company | Immunomodulators |
| WO2016126646A1 (en) * | 2015-02-04 | 2016-08-11 | Bristol-Myers Squibb Company | Immunomodulators |
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| KR20190075118A (ko) | 2019-06-28 |
| US10988507B2 (en) | 2021-04-27 |
| ES2910832T3 (es) | 2022-05-13 |
| JP2020502049A (ja) | 2020-01-23 |
| KR102526034B1 (ko) | 2023-04-25 |
| US20190322704A1 (en) | 2019-10-24 |
| WO2018085750A3 (en) | 2018-06-14 |
| JP7085545B2 (ja) | 2022-06-16 |
| CN110267971A (zh) | 2019-09-20 |
| WO2018085750A2 (en) | 2018-05-11 |
| EP3535280A2 (en) | 2019-09-11 |
| EP3535280B1 (en) | 2022-03-16 |
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