CN110151674A - A kind of Essence of astaxanthin-containing - Google Patents

A kind of Essence of astaxanthin-containing Download PDF

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Publication number
CN110151674A
CN110151674A CN201910402239.4A CN201910402239A CN110151674A CN 110151674 A CN110151674 A CN 110151674A CN 201910402239 A CN201910402239 A CN 201910402239A CN 110151674 A CN110151674 A CN 110151674A
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Prior art keywords
astaxanthin
essence
natrulon
containing according
following component
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CN201910402239.4A
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赖玉珍
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Guangzhou Ifis Biotechnology Co Ltd
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Guangzhou Ifis Biotechnology Co Ltd
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Priority to CN201910402239.4A priority Critical patent/CN110151674A/en
Publication of CN110151674A publication Critical patent/CN110151674A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The purpose of the present invention is preparing a kind of Essence of stable astaxanthin-containing, does not generate precipitating, floccule, layering, phenomena such as fading during preservation and use, and guarantee that its antioxidant activity maintains certain level during this period.A kind of Essence of astaxanthin-containing of the present invention, its ingredient includes water, butanediol, bright string coccus/radish (RAPHANUS SATIVUS) root tunning filtrate, Cer NS, lecithin, tocopherol acetate, octyl dodecanol, glycerol, Polyoxyethylene Sorbitan Monooleate, astaxanthin, Natrulon H-10 oleate, caprylic/capric triglyceride, haematococcus pluvialis (HAEMATOCOCCUS PLUVIALIS) extract, Natrulon H-10 stearate, lysolecithin, Sodium Hyaluronate, beta glucan, parahydroxyacet-ophenone, 1, 2- hexylene glycol, hydroxyethyl cellulose, saualane, EDETATE SODIUM.

Description

A kind of Essence of astaxanthin-containing
Technical field
The invention belongs to technical field of skin care, are related to a kind of Essence of astaxanthin-containing.
Background technique
Solar irradiation, ultraviolet light irradiation, air pollution in environment and the stress in work etc. can be such that human body generates Active oxygen radical, excessive active oxygen radical have destruction to human body macromolecular complex, accelerates aging and the skin of people Damage, to remove the important method that free radical is anti-aging.Astaxanthin has anti-aging effects, astaxanthin in skin care item Senile-resistant efficacy more and more confirmed.
Astaxanthin is the strongest antioxidant of nature of mankind's discovery so far, can remove excessive free radical, Radical damage is protected cells from, to improve body to the power of resisting of external injury, antioxidant activity is considerably beyond now There is antioxidant, the ability for removing free radical is 1000 times of natural VE.
Since astaxanthin is a kind of natural carotenoid, belongs to terpenes unsaturated compounds, be soluble in oil, indissoluble Yu Shui, easy oxidation by air, so the aqueous solution Essence containing astaxanthin, belongs to emulsion state more, since astaxanthin is in water In be difficult to stablize, uniform dispersion, easily there is precipitating, generate floccule, the unstable quality phenomenon such as layering;Again due to shrimp blueness Element is easily oxidized, and is easy to appear phenomena such as generation is faded, antioxidant activity reduces, is influenced its service life and validity.
Summary of the invention
The purpose of the present invention is preparing a kind of Essence of stable astaxanthin-containing, it is heavy not generate during preservation and use Phenomena such as shallow lake, floccule, layering, colour fading, and guarantee that its antioxidant activity maintains certain level during this period.
The Essence of astaxanthin-containing of the present invention includes water, emulsifier, moisturizer, active constituent, preservative, chelating agent, rouge Matter and thickener, the active constituent include astaxanthin and bright string coccus/radish root tunning filtrate, and the astaxanthin is by rain Raw haematococcus is that raw material is extracted and obtained.The emulsifier consists of the following compositions: lecithin, lysolecithin, Natrulon H-10 oil Acid esters, Natrulon H-10 stearate.The moisturizer consists of the following compositions: 1,2- hexylene glycol, glycerol, Sodium Hyaluronate, β- Glucan, saualane, Cer NS, butanediol.The preservative is selected from following component: parahydroxyacet-ophenone.The lipid by Following component composition: caprylic/capric triglyceride, octyl dodecanol, tocopherol acetate, Polyoxyethylene Sorbitan Monooleate.The thickening Agent is selected from following component: hydroxyethyl cellulose.The chelating agent is selected from following component EDTA- disodium.
To sum up, a kind of Essence of astaxanthin-containing of the present invention, ingredient includes water, butanediol, bright string coccus/radish It is (RAPHANUS SATIVUS) root tunning filtrate, Cer NS, lecithin, tocopherol acetate, octyl dodecanol, sweet Oil, Polyoxyethylene Sorbitan Monooleate, astaxanthin, Natrulon H-10 oleate, caprylic/capric triglyceride, haematococcus pluvialis (HAEMATOCOCCUS PLUVIALIS) extract, Natrulon H-10 stearate, lysolecithin, Sodium Hyaluronate, β-Portugal Glycan, parahydroxyacet-ophenone, 1,2- hexylene glycol, hydroxyethyl cellulose, saualane, EDETATE SODIUM.
It is matched: butanediol (2.00-8.00%w/v), the fermentation of bright string coccus/radish (RAPHANUS SATIVUS) root produce Object filtrate (1.00-6.00%w/v), Cer NS (0.08-0.30%w/v), lecithin (0.01-0.02%w/v), fertility Phenol acetic acid esters (0.01-0.02%w/v), octyl dodecanol (0.01-0.02%w/v), glycerol (0.03-0.11%w/v), poly- mountain Pears alcohol ester -80 (0.01-0.02%w/v), astaxanthin (0.05-0.20%w/v), Natrulon H-10 oleate (0.001- 0.002%w/v), caprylic/capric triglyceride (0.01-0.02%w/v), haematococcus pluvialis (HAEMATOCOCCUS PLUVIALIS) extract (0.01-0.02%w/v), Natrulon H-10 stearate (0.01-0.02%w/v), lysolecithin (0.01-0.02%w/v), Sodium Hyaluronate (0.10-1.00%w/v), beta glucan (0.30-1.20%w/v), para hydroxybenzene Ethyl ketone (0.01-0.02%w/v), 1,2- hexylene glycol (0.01-0.02%w/v), hydroxyethyl cellulose (0.05-0.20%w/v), Saualane (0.50-1.00%w/v), EDETATE SODIUM (0.01-0.08%w/v), surplus is water.
The Essence of astaxanthin-containing obtained in this ratio range, properties of product are stablized, and room temperature, dark place are placed 6 months Sample is uniform, stablizes, and uses astaxanthin Essence made from the proportion outside this range, goes out after room temperature, dark place are placed 6 months Now precipitating, floccule, layering, discolouration phenomena.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this The embodiment of invention for those of ordinary skill in the art without creative efforts, can also basis The attached drawing of offer obtains other attached drawings.
Fig. 1 is the cross-reference sample pictures after the Essence room temperature dark place of astaxanthin-containing in the prior art is placed 6 months, 1 is fades, and 2 be precipitating+colour fading, and 3 be layering, and 4 be precipitating;
Fig. 2 be astaxanthin-containing of the present invention Essence according to the proportion 1 prepare sample room temperature dark place place 6 months before and after Comparison diagram;
Fig. 3 be astaxanthin-containing of the present invention Essence according to the proportion 2 prepare sample room temperature dark places place 6 months before and after Comparison diagram;
Fig. 4 be astaxanthin-containing of the present invention Essence according to the proportion 3 prepare sample room temperature dark places place 6 months before and after Comparison diagram.
Specific embodiment
The purpose of the present invention is preparing a kind of Essence of stable astaxanthin-containing, it is heavy not generate during preservation and use Phenomena such as shallow lake, floccule, layering, colour fading, and guarantee that its antioxidant activity maintains certain level during this period.
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
The Essence of astaxanthin-containing, ingredient include water, Cer NS, lecithin, octyl dodecanol, polysorbate- 80, parahydroxyacet-ophenone, 1,2- hexylene glycol, astaxanthin, glycerol, Natrulon H-10 oleate, caprylic/capric triglyceride, rain are raw Haematococcus (HAEMATOCOCCUS PLUVIALIS) extract, Natrulon H-10 stearate, lysolecithin, tocopheryl acetate Ester, Sodium Hyaluronate, beta glucan, hydroxyethyl cellulose, saualane, EDETATE SODIUM, bright string coccus/radish (Raphanus Sativus) root tunning filtrate.
A kind of Essence of astaxanthin-containing of the present invention, ingredient includes water, butanediol, bright string coccus/radish (RAPHANUS SATIVUS) root tunning filtrate, Cer NS, lecithin, tocopherol acetate, octyl dodecanol, glycerol, polysorbate Ester -80, astaxanthin, Natrulon H-10 oleate, caprylic/capric triglyceride, haematococcus pluvialis (HAEMATOCOCCUS PLUVIALIS) extract, Natrulon H-10 stearate, lysolecithin, Sodium Hyaluronate, beta glucan, para hydroxybenzene second Ketone, 1,2- hexylene glycol, hydroxyethyl cellulose, saualane, EDETATE SODIUM.
The proportion 1 of mentioned component are as follows: butanediol (2.00%w/v), bright string coccus/radish (RAPHANUS SATIVUS) root Tunning filtrate (1.00%w/v), Cer NS (0.08%w/v), lecithin (0.01%w/v), tocopherol acetate (0.01%w/v), octyl dodecanol (0.01%w/v), glycerol (0.03%w/v), Polyoxyethylene Sorbitan Monooleate (0.01%w/v), shrimp Green element (0.05%w/v), Natrulon H-10 oleate (0.001%w/v), caprylic/capric triglyceride (0.01%w/v), rain are raw Haematococcus (HAEMATOCOCCUS PLUVIALIS) extract (0.01%w/v), Natrulon H-10 stearate (0.01%w/ V), lysolecithin (0.01%w/v), Sodium Hyaluronate (0.10%w/v), beta glucan (0.30%w/v), para hydroxybenzene second Ketone (0.01%w/v), 1,2- hexylene glycol (0.01%w/v), hydroxyethyl cellulose (0.05%w/v), saualane (0.50%w/ V), EDETATE SODIUM (0.01%w/v), surplus are water.
After the sample for the astaxanthin-containing Essence prepared according to proportion 1 is placed 6 months in room temperature, dark place, as shown in Fig. 2, Sample is stable, it is uniform, without discolouration phenomena, no precipitating, layering, floccule generate.
Embodiment 2
A kind of Essence of astaxanthin-containing of the present invention, ingredient includes water, butanediol, bright string coccus/radish (RAPHANUS SATIVUS) root tunning filtrate, Cer NS, lecithin, tocopherol acetate, octyl dodecanol, glycerol, polysorbate Ester -80, astaxanthin, Natrulon H-10 oleate, caprylic/capric triglyceride, haematococcus pluvialis (HAEMATOCOCCUS PLUVIALIS) extract, Natrulon H-10 stearate, lysolecithin, Sodium Hyaluronate, beta glucan, para hydroxybenzene second Ketone, 1,2- hexylene glycol, hydroxyethyl cellulose, saualane, EDETATE SODIUM.
The proportion 2 of mentioned component is butanediol (6.00%w/v), bright string coccus/radish (RAPHANUS SATIVUS) root Tunning filtrate (3.00%w/v), Cer NS (0.22%w/v), lecithin (0.01%w/v), tocopherol acetate (0.01%w/v), octyl dodecanol (0.01%w/v), glycerol (0.08%w/v), Polyoxyethylene Sorbitan Monooleate (0.01%w/v), shrimp Green element (0.15%w/v), Natrulon H-10 oleate (0.001%w/v), caprylic/capric triglyceride (0.01%w/v), rain are raw Haematococcus (HAEMATOCOCCUS PLUVIALIS) extract (0.01%w/v), Natrulon H-10 stearate (0.01%w/ V), lysolecithin (0.01%w/v), Sodium Hyaluronate (0.40%w/v), beta glucan (0.50%w/v), para hydroxybenzene second Ketone (0.01%w/v), 1,2- hexylene glycol (0.01%w/v), hydroxyethyl cellulose (0.13%w/v), saualane (0.60%w/ V), EDETATE SODIUM (0.03%w/v).
After the sample for the astaxanthin-containing Essence prepared according to proportion 2 is placed 6 months in room temperature, dark place, as shown in figure 3, Sample is stable, it is uniform, without discolouration phenomena, no precipitating, layering, floccule generate.
Embodiment 3
A kind of Essence of astaxanthin-containing of the present invention, ingredient includes water, butanediol, bright string coccus/radish (RAPHANUS SATIVUS) root tunning filtrate, Cer NS, lecithin, tocopherol acetate, octyl dodecanol, glycerol, polysorbate Ester -80, astaxanthin, Natrulon H-10 oleate, caprylic/capric triglyceride, haematococcus pluvialis (HAEMATOCOCCUS PLUVIALIS) extract, Natrulon H-10 stearate, lysolecithin, Sodium Hyaluronate, beta glucan, para hydroxybenzene second Ketone, 1,2- hexylene glycol, hydroxyethyl cellulose, saualane, EDETATE SODIUM.
The proportion 3 of mentioned component is butanediol (8.00%w/v), bright string coccus/radish (RAPHANUS SATIVUS) root Tunning filtrate (6.00%w/v), Cer NS (0.30%w/v), lecithin (0.02%w/v), tocopherol acetate (0.02%w/v), octyl dodecanol (0.02%w/v), glycerol (0.11%w/v), Polyoxyethylene Sorbitan Monooleate (0.02%w/v), shrimp Green element (0.20%w/v), Natrulon H-10 oleate (0.002%w/v), caprylic/capric triglyceride (0.02%w/v), rain are raw Haematococcus (HAEMATOCOCCUS PLUVIALIS) extract (0.02%w/v), Natrulon H-10 stearate (0.02%w/ V), lysolecithin (0.02%w/v), Sodium Hyaluronate (1.00%w/v), beta glucan (1.20%w/v), para hydroxybenzene second Ketone (0.02%w/v), 1,2- hexylene glycol (0.02%w/v), hydroxyethyl cellulose (0.20%w/v), saualane (1.00%w/ V), EDETATE SODIUM (0.08%w/v).
After the sample for the astaxanthin-containing Essence prepared according to proportion 3 is placed 6 months in room temperature, dark place, as shown in figure 4, Sample is stable, it is uniform, without discolouration phenomena, no precipitating, layering, floccule generate.
According to the Essence of proportion prepared astaxanthin-containing of the embodiment of the present invention 1 into embodiment 3, room temperature dark place is put It is uniform after setting six months, stable, colour fading, floccule, precipitating and the lamination occurred in no control sample, that is, Fig. 1.
To sum up, the Essence of prepared astaxanthin-containing is matched according to the present invention, and room temperature 6 months, system was uniform, steady It is fixed, do not occur precipitating, floccule, layering and discolouration phenomena.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although with reference to the foregoing embodiments Invention is explained in detail, those skilled in the art should understand that: it still can be to aforementioned each implementation Technical solution documented by example is modified or equivalent replacement of some of the technical features;And these modification or Replacement, the spirit and scope for technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution.

Claims (8)

1. a kind of Essence of astaxanthin-containing, which is characterized in that including water, emulsifier, moisturizer, active constituent, preservative, chela Mixture, lipid and thickener, the active constituent include astaxanthin and bright string coccus/radish root tunning filtrate, the shrimp Green element is raw material extraction by haematococcus pluvialis and is obtained.
2. the Essence of astaxanthin-containing according to claim 1, which is characterized in that the emulsifier is by following component group At: lecithin, lysolecithin, Natrulon H-10 oleate, Natrulon H-10 stearate.
3. the Essence of astaxanthin-containing according to claim 2, which is characterized in that the moisturizer is by following component group At: 1,2- hexylene glycol, glycerol, Sodium Hyaluronate, beta glucan, saualane, Cer NS, butanediol.
4. the Essence of astaxanthin-containing according to claim 3, which is characterized in that the preservative is selected from following component: Parahydroxyacet-ophenone.
5. the Essence of astaxanthin-containing according to claim 4, which is characterized in that the lipid consists of the following compositions: Caprylic/capric triglyceride, octyl dodecanol, tocopherol acetate, Polyoxyethylene Sorbitan Monooleate.
6. the Essence of astaxanthin-containing according to claim 5, which is characterized in that the thickener is selected from following component: Hydroxyethyl cellulose.
7. the Essence of astaxanthin-containing according to claim 6, which is characterized in that the chelating agent is selected from following component: EDTA- disodium.
8. the Essence of astaxanthin-containing according to claim 7, which is characterized in that the proportion of Essence are as follows: butanediol is 2.00-8.00%w/v, bright string coccus/radish root tunning filtrate is 1.00-6.00%w/v, Cer NS 0.08- 0.30%w/v, lecithin 0.01-0.02%w/v, tocopherol acetate 0.01-0.02%w/v, octyl dodecanol are 0.01-0.02%w/v, glycerol 0.03-0.11%w/v, Polyoxyethylene Sorbitan Monooleate 0.01-0.02%w/v, astaxanthin are 0.05-0.20%w/v, Natrulon H-10 oleate be 0.001-0.002%w/v, caprylic/capric triglyceride 0.01- 0.02%w/v, haematococcus pluvialis extract are 0.01-0.02%w/v, Natrulon H-10 stearate be 0.01-0.02%w/v, Lysolecithin is 0.01-0.02%w/v, Sodium Hyaluronate 0.10-1.00%w/v, beta glucan 0.30-1.20%w/ V, parahydroxyacet-ophenone be 0.01-0.02%w/v, 1,2- hexylene glycol be 0.01-0.02%w/v, hydroxyethyl cellulose 0.05- 0.20%w/v, saualane 0.50-1.00%w/v, EDETATE SODIUM 0.01-0.08%w/v.
CN201910402239.4A 2019-05-15 2019-05-15 A kind of Essence of astaxanthin-containing Pending CN110151674A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110522666A (en) * 2019-09-26 2019-12-03 杭州兰茜化妆品有限公司 A kind of astaxanthin Essence and its preparation process
CN111388340A (en) * 2020-04-13 2020-07-10 上海新高姿化妆品有限公司 Stable astaxanthin essence and preparation method thereof
CN111557861A (en) * 2020-05-29 2020-08-21 广州市百好博有限公司 High-efficiency stable light-resistant and oxidation-resistant composition and application thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232442A (en) * 2015-11-18 2016-01-13 中山市艾丽意素生物科技有限公司 Plant antioxidation amino acid cleanser and preparation method thereof
CN105250187A (en) * 2015-11-18 2016-01-20 中山市艾丽意素生物科技有限公司 Plant active peptide firming facial mask essence and application thereof
CN106214512A (en) * 2016-08-22 2016-12-14 欧诗漫生物股份有限公司 A kind of essence containing Cer NS & carnosine submicron liposome and preparation method thereof
CN106963670A (en) * 2017-04-19 2017-07-21 北京赛尔佳人化妆品有限公司 A kind of marine alga moisture saver mask liquid and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232442A (en) * 2015-11-18 2016-01-13 中山市艾丽意素生物科技有限公司 Plant antioxidation amino acid cleanser and preparation method thereof
CN105250187A (en) * 2015-11-18 2016-01-20 中山市艾丽意素生物科技有限公司 Plant active peptide firming facial mask essence and application thereof
CN106214512A (en) * 2016-08-22 2016-12-14 欧诗漫生物股份有限公司 A kind of essence containing Cer NS & carnosine submicron liposome and preparation method thereof
CN106963670A (en) * 2017-04-19 2017-07-21 北京赛尔佳人化妆品有限公司 A kind of marine alga moisture saver mask liquid and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110522666A (en) * 2019-09-26 2019-12-03 杭州兰茜化妆品有限公司 A kind of astaxanthin Essence and its preparation process
CN111388340A (en) * 2020-04-13 2020-07-10 上海新高姿化妆品有限公司 Stable astaxanthin essence and preparation method thereof
CN111557861A (en) * 2020-05-29 2020-08-21 广州市百好博有限公司 High-efficiency stable light-resistant and oxidation-resistant composition and application thereof

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Application publication date: 20190823