CN107412050A - One kind repairs senescense and damnification facial mask - Google Patents

One kind repairs senescense and damnification facial mask Download PDF

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Publication number
CN107412050A
CN107412050A CN201710583394.1A CN201710583394A CN107412050A CN 107412050 A CN107412050 A CN 107412050A CN 201710583394 A CN201710583394 A CN 201710583394A CN 107412050 A CN107412050 A CN 107412050A
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CN
China
Prior art keywords
facial mask
senescense
damnification
wintergreen
polyphenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710583394.1A
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Chinese (zh)
Inventor
吴义荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Foshan Jucheng Biochemical Technology Research and Development Co Ltd
Original Assignee
Foshan Jucheng Biochemical Technology Research and Development Co Ltd
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Publication date
Application filed by Foshan Jucheng Biochemical Technology Research and Development Co Ltd filed Critical Foshan Jucheng Biochemical Technology Research and Development Co Ltd
Priority to CN201710583394.1A priority Critical patent/CN107412050A/en
Publication of CN107412050A publication Critical patent/CN107412050A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

The invention discloses one kind to repair senescense and damnification facial mask.The plant composition being made up of sowthistle antioxidase, trifolium pratense L. isoflavones, wintergreen polyphenol is added in facial mask, wherein, trifolium pratense L. isoflavones can effectively improve the situation of the polyphenoils and enzyme system activity decrease in cell;Sowthistle contains abundant antioxidase simultaneously, effectively free radical can be prevented to generate, remove excessive free radical and other peroxide matter;Wintergreen polyphenol can directly provide sufficient activity proton and be combined with free radical or other peroxidating materials, and further stabilization simultaneously eliminates free radical, and three kinds of compositions collaborations are anti-oxidant, cooperate with skin care, so that facial mask reaches significant delaying skin aging effect;And facial mask can provide skin and provide the nutriments such as dimension E, amino acid, and then the synthesis of collagen is promoted, accelerate the reparation of damaged cell.

Description

One kind repairs senescense and damnification facial mask
Technical field
The present invention relates to cosmetic field, and in particular to one kind repairs senescense and damnification facial mask.
Background technology
Always life must through stage.From pathology, aging is stress and to strain, and damage and infection, immune response decline Move back, subalimentation, dysbolism and the result of carelessness and abuse accumulation.Occur variety of problems as wrinkled with the passing of the years Line, relaxation, color spot, low and deep etc..Anti-aging is to help to reduce the generation of free radical by supplementing polyphenoils, increases skin Elasticity, while replenishing collagen or ferment, anti-aging dietotherapy side and antisenility skin care skin care products all delaying sanilities.In recent years Come, with the raising of people's living standard and itself health care consciousness, people carry out the trust of skin care using skin care item More and more higher is spent, safely and effectively product is always consumer demand.
In the prior art, there is antiaging agent, although there is certain retarding action to aging, these medicines pair The body of patient also result in very big injury.Commercially available anti-aging cosmetics contain greatly various chemical synthesis hormones very much, to body Body has side effect, it is difficult to meets consumer demand.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide one kind to repair senescense and damnification facial mask, and safely, effectively Ground has the function that anti-aging and repairs skin damage.
In order to achieve the above object, the present invention provides following technical scheme:
A kind of senescense and damnification facial mask of repairing includes the plant composition that mass percent is 0.5-5%;Wherein, the plant Composition is made up of sowthistle antioxidase, trifolium pratense L. isoflavones, wintergreen polyphenol, and sowthistle antioxidase, screw oil expeller axle Careless isoflavones, the weight ratio of wintergreen polyphenol are (0.1-1):(0.2-2):(0.2-2).
The preparation method of the trifolium pratense L. isoflavones comprises the following steps:Red clover is cleaned into removal of impurities, dried, is crushed 40-60 mesh sieves are crossed, by solid-liquid ratio 1:(5-15) adds 50-80% ethanol, the water-bath refluxing extraction 1-2h at 50-80 DEG C, extraction 3 It is secondary, filter, through spin concentration after merging filtrate, obtain trifolium pratense L. isoflavones.
The preparation method of the wintergreen polyphenol comprises the following steps:Wintergreen is cleaned into removal of impurities, drying, crushed 40- 60 mesh sieves, by solid-liquid ratio 1:(10-20) adds 70-95% ethanol, ultrasonic extraction 1-2h, ultrasonic power 30- at 40-60 DEG C 50W, extract solution 3500-4000r/min centrifuge 10-30min, take supernatant, rotated concentration, obtain wintergreen polyphenol.
The facial mask also includes following component:Erythrite 2-6%, ethanol 0.1-3%, dipropylene glycol 2-8%, butanediol 5- 15%th, glycerine 2-8%, potassium hydroxide 0.01-0.1%, Phenoxyethanol 0.01-0.2%, EDETATE SODIUM 0.01-0.1%, xanthan Glue 0.1-0.3%, PEG/PPG-14/7 dimethyl ether 1-6%, PPG-13- decyl tetradecyl alcohol polyethers -242-8%, tocopherol 0.1-0.5%, carbomer 0.1-0.3%, Sodium Hyaluronate 0.02-0.1%, methyl hydroxybenzoate 0.01-0.2%, polyquaternium- 510.01-0.3%, deionized water surplus.
The present invention also provides a kind of preparation method for repairing senescense and damnification facial mask, comprises the following steps:
(1) by erythrite, ethanol, dipropylene glycol, butanediol, glycerine, EDETATE SODIUM, xanthans, PEG/PPG-14/7 bis- Methyl ether, tocopherol, carbomer, Sodium Hyaluronate, methyl hydroxybenzoate, deionized water, which mix, is heated to 80-85 DEG C, and stirring is molten Solution is uniform;
(2) under stirring, PPG-13- decyl tetradecyl alcohols polyethers -24, polyquaternium -51 are added, stirring and dissolving is complete;Cooling To 45-50 DEG C, potassium hydroxide is added, is stirred, is added above-mentioned plant composition, Phenoxyethanol, stir, cool down out Material.
To the Activities of Some Plants of the present invention into being allocated as introducing as follows:
Sowthistle also known as bitter dish, field sowthistle herb, bitter Pueraria lobota dish, numb dish etc. is taken, belong to composite family herbaceos perennial.Sowthistle nutrition Composition is extremely abundant, containing abundant mineral element, contains multiple proteins, therefore rich amino acids simultaneously.In addition lettuce Mai dishes have complete oxidation protection system, are due to sowthistle rich in the various antioxidases based on SOD, can effectively prevent Free radical is formed, and is removed and formed free radical, and then prevents the cell biological film for triggering or aggravating due to materials such as free radicals System destruction damages.
Red clover is leguminous perennial herb, also known as red clover, red clover, red bean grass, clover etc., screw oil expeller Axle grass extract contains flavonoids, protein, amino acid, carbohydrate and vitamin ingredients, wherein most important active material is yellow Isoflavones in ketone.Trifolium pratense L. isoflavones can protect the not oxidized destructions of DNA, effectively eliminate UV-induced gene damage Wound;Ascorbic oxidation can be prevented, ultra-oxygen anion free radical and hydroxy radical can be removed, can also suppress the peroxidating of lipid Effect;All kinds of enzymatic activitys in enzyme system can also be effectively improved, reduce the aging performance of senile cell.
Wintergreen extract contains various active material, including the material such as phenol quinones, glycoside, flavonoids and organic acid. What the present invention mainly utilized is wintergreen polyphenol.Phenolic hydroxyl group on wintergreen polyphenol can provide the active proton of abundance, and it is strong also Proper energy power will form the hydroperoxyl radical of sufficient antioxidation, can react to form stabilization with intracellular unnecessary living radical Material, the oxidability of free radical is balanced out, make Cellular Oxidation integrated compensation;Further, since the structure of plant polyphenol is special, Light radiation can be absorbed, and absorption region is broad, the radiation to ultraviolet light and visible-range has absorption, can play anti- Radiation effects.
Compared with prior art, it is the device have the advantages that as follows:(1) plant society of facial mask of the invention addition Thing is made up of sowthistle antioxidase, trifolium pratense L. isoflavones, wintergreen polyphenol, wherein, trifolium pratense L. isoflavones can effectively change The situation of polyphenoils and enzyme system activity decrease in kind cell;Sowthistle contains abundant antioxidase simultaneously, can have Effect prevents free radical from generating, and removes excessive free radical and other peroxide matter;Wintergreen polyphenol can directly provide sufficient work Property is simultaneously combined with free radical or other peroxidating materials, and further stabilization simultaneously eliminates free radical, and three kinds of compositions cooperate with antioxygens Change, cooperate with skin care, so that facial mask reaches significant delaying skin aging effect;(2) facial mask of the invention can provide skin and carry For nutriments such as dimension E, amino acid, and then the synthesis of collagen is promoted, accelerate the reparation of damaged cell;(3) it is of the invention Facial mask composition safety, do not stimulate gently, human body had no toxic side effect.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
1-5 of the embodiment of the present invention present invention repairs senescense and damnification face pack prescription and is shown in Table 1
Table 1
The preparation method of above-mentioned trifolium pratense L. isoflavones is as follows:
Red clover is cleaned into removal of impurities, drying, 40 mesh sieves are crushed, by solid-liquid ratio 1:10 add 70% ethanol, in 80 DEG C Lower water-bath refluxing extraction 1.5h, extract 3 times, filtering, through spin concentration after merging filtrate, obtain trifolium pratense L. isoflavones.
The preparation method of above-mentioned wintergreen polyphenol is as follows:
Wintergreen is cleaned into removal of impurities, drying, 40 mesh sieves are crushed, by solid-liquid ratio 1:15 add 70% ethanol, at 50 DEG C Ultrasonic extraction 1.5h, ultrasonic power 40W, extract solution 3500r/min centrifugation 20min, take supernatant, rotated concentration, obtain deer Hoof grass polyphenol.
A kind of preparation methods of reparation senescense and damnification facial mask of embodiment 1-5 are as follows:
(3) by erythrite, ethanol, dipropylene glycol, butanediol, glycerine, EDETATE SODIUM, xanthans, PEG/PPG-14/7 bis- Methyl ether, tocopherol, carbomer, Sodium Hyaluronate, methyl hydroxybenzoate, deionized water, which mix, is heated to 85 DEG C, stirring and dissolving Uniformly;
(4) under stirring, PPG-13- decyl tetradecyl alcohols polyethers -24, polyquaternium -51 are added, stirring and dissolving is complete;Cooling To 45 DEG C, potassium hydroxide is added, is stirred, is added above-mentioned plant composition, Phenoxyethanol, stir, cooling discharging.
Comparative example 1
Difference with embodiment 1 is not add sowthistle antioxidase, other preparation conditions and method and the phase of embodiment 1 Together.
Comparative example 2
Difference with embodiment 1 is not add trifolium pratense L. isoflavones, other preparation conditions and method and the phase of embodiment 1 Together.
Comparative example 3
Difference with embodiment 1 is not add wintergreen polyphenol, and other preparation conditions and method are same as Example 1.
Comparative example 4
Difference with embodiment 1 is not add plant composition, and other preparation conditions and method are same as Example 1.
Antioxidative Activity Determination
Compound concentration is 1 × 10-4mol/L DPPH ethanol solutions.It will be obtained in embodiment 1-5 and comparative example 1-4 The reparation senescense and damnification facial mask arrived, at the same using it is a it is commercially available declare to have good anti-ageing face mask as control group, with 80% second Alcohol is configured to the testing sample solution that concentration is respectively 0.01,0.04,0.08,0.10,0.12,0.16,0.20,0.24,0.26. 5mL sample solutions and DPPH solution are taken respectively, and is well mixed, and avoid light place 30min, are returned to zero with 80% ethanol, Absorbance A i is determined at 517BITI;Same method, take 5mL80% alcohol solvents to be mutually mixed uniformly with sample solution respectively, keep away Light determines absorbance A j after placing 30min;5mL80% alcohol solvents add 5mLDP.PH- solution to mix, avoid light place 30rain, Determine absorbance A c.Finally free radical scavenging activity is calculated according to below equation:IP%=[1 one (Ai-Aj)/Ac] × 100, formula Middle Ai is sample and the absorption values after DP-PH effects;Aj is
Contribution of the sample itself to absorbance;Ac is DPPH itself absorption.
Knot is determined to embodiment 1-5, comparative example the 1-4 ability for repairing senescense and damnification facial mask and control group removing DPPH Fruit is shown in Table 2
Table 2
As shown in Table 2, it is removed DPPH ability and increased with the increase of each extraction moiety concentrations.
Data above shows the obtained antioxidation activities for repairing senescense and damnification facial mask of embodiment 1-5 apparently higher than comparative example 1-4 and control group, it is seen that the present invention is repaired in senescense and damnification facial mask, sowthistle antioxidase, trifolium pratense L. isoflavones and deer hoof Careless polyphenol Synergistic, and the weight ratio of sowthistle antioxidase, trifolium pratense L. isoflavones and wintergreen polyphenol is (0.1-1): (0.2-2):Best results when (0.2-2), three kinds of composition collaborations are anti-oxidant, cooperate with skin care, significantly prolong so that facial mask reaches Slow skin aging effect, prevent and repair due to each kinds of oxidation reaction and caused by cellular damage.
Above example only illustrates embodiment of the present invention, does not have any formal limitation to the present invention;Appoint What is engaged in professional and technical personnel, all has the ability to make some changes or modification using the technology contents disclosed, turns into equivalent The equivalent embodiment of change, according to the technology of the present invention essence, simple modification, equivalent change and modification is carried out to the present invention, belonged to In the range of technical solution of the present invention.

Claims (6)

1. one kind repairs senescense and damnification facial mask, it is characterised in that the facial mask includes the plant group that mass percent is 0.5-5% Compound;
Wherein, the plant composition is made up of sowthistle antioxidase, trifolium pratense L. isoflavones, wintergreen polyphenol.
A kind of 2. reparation senescense and damnification facial mask according to claim 1, it is characterised in that the sowthistle antioxidase, Trifolium pratense L. isoflavones, the weight ratio of wintergreen polyphenol are (0.1-1):(0.2-2):(0.2-2).
3. a kind of reparation senescense and damnification facial mask according to claim 1, it is characterised in that the trifolium pratense L. isoflavones Preparation method comprises the following steps:
Red clover is cleaned into removal of impurities, drying, 40-60 mesh sieves are crushed, by solid-liquid ratio 1:(5-15) adds 50-80% ethanol, The water-bath refluxing extraction 1-2h at 50-80 DEG C, extract 3 times, filtering, through spin concentration after merging filtrate, it is different to obtain red clover Flavones.
A kind of 4. reparation senescense and damnification facial mask according to claim 1, it is characterised in that the preparation of the wintergreen polyphenol Method comprises the following steps:
Wintergreen is cleaned into removal of impurities, drying, 40-60 mesh sieves are crushed, by solid-liquid ratio 1:(10-20) adds 70-95% ethanol, in Ultrasonic extraction 1-2h at 40-60 DEG C, ultrasonic power 30-50W, extract solution 3500-4000r/min centrifugation 10-30min, take supernatant Liquid, rotated concentration, obtain wintergreen polyphenol.
A kind of repair senescense and damnification facial mask 5. according to claim 1, it is characterised in that the facial mask also include below into Point:
Erythrite 2-6%, ethanol 0.1-3%, dipropylene glycol 2-8%, butanediol 5-15%, glycerine 2-8%, potassium hydroxide 0.01-0.1%, Phenoxyethanol 0.01-0.2%, EDETATE SODIUM 0.01-0.1%, xanthans 0.1-0.3%, PEG/PPG-14/7 Dimethyl ether 1-6%, PPG-13- decyl tetradecyl alcohol polyethers -242-8%, tocopherol 0.1-0.5%, carbomer 0.1-0.3%, Sodium Hyaluronate 0.02-0.1%, methyl hydroxybenzoate 0.01-0.2%, polyquaternium -510.01-0.3%, deionized water surplus.
6. it is a kind of as described in claim any one of 1-5 repair senescense and damnification facial mask preparation method, it is characterised in that including with Lower step:
(1) by erythrite, ethanol, dipropylene glycol, butanediol, glycerine, EDETATE SODIUM, xanthans, PEG/PPG-14/7 dimethyl Ether, tocopherol, carbomer, Sodium Hyaluronate, methyl hydroxybenzoate, deionized water, which mix, is heated to 80-85 DEG C, and stirring and dissolving is equal It is even;
(2) under stirring, PPG-13- decyl tetradecyl alcohols polyethers -24, polyquaternium -51 are added, stirring and dissolving is complete;It is cooled to 45- 50 DEG C, potassium hydroxide is added, is stirred, added plant composition as claimed in claim 1, Phenoxyethanol, stir, Cooling discharging.
CN201710583394.1A 2017-07-15 2017-07-15 One kind repairs senescense and damnification facial mask Withdrawn CN107412050A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110478282A (en) * 2019-09-11 2019-11-22 黑龙江省科学院火山与矿泉研究所 A kind of multi-functional volcanic slurry cleaning mud film and preparation method thereof and application method
CN112972321A (en) * 2019-12-16 2021-06-18 兰州大学 Natural antioxidant for cosmetics and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110478282A (en) * 2019-09-11 2019-11-22 黑龙江省科学院火山与矿泉研究所 A kind of multi-functional volcanic slurry cleaning mud film and preparation method thereof and application method
CN112972321A (en) * 2019-12-16 2021-06-18 兰州大学 Natural antioxidant for cosmetics and preparation method thereof

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