CN110123695A - A kind of cellular energy remediation composition - Google Patents
A kind of cellular energy remediation composition Download PDFInfo
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- CN110123695A CN110123695A CN201910476703.4A CN201910476703A CN110123695A CN 110123695 A CN110123695 A CN 110123695A CN 201910476703 A CN201910476703 A CN 201910476703A CN 110123695 A CN110123695 A CN 110123695A
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
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Abstract
The invention belongs to daily chemicals fields.A kind of cellular energy remediation composition, contain amino acid humectant 0.2-5%, Sodium Hyaluronate 0.005-0.2%, allantoin 0.5-1.5%, polyglutamic acid sodium 0.002-2%, compound biological enzyme 0.3-1.0%, 1,3- butanediol 1-3%, glycosylglycerol 0.001-2%, preservative 0.53-8%, close Luo Muye/stem extraction 0.001-1%, water complement to 100%.The present invention enough provides rapid comprehensive intensive moisturizing for skin, assigns nutrition skin living, improves skin immunity, quick sterilization anti-inflammatory, detumescence healing;With whitening, light spot, light tone, compact crease-resistant anti-wrinkle, the U.S. face of nourishing and other effects, it can quickly be repaired in sunburn reparation, micro- whole, laser, the postoperative use of water light, it is a kind of with very strong maintenance ability, the cellular energy maintenance product of moistening beautiful tender with rear skin.
Description
Technical field
The invention belongs to daily chemicals fields, and being related to one kind has replenishing water and preserving moisture, improves skin immunity, and quick sterilization anti-inflammatory disappears
It is swollen, the composition of the multiple efficacies such as quick reparation.
Background technique
Skin problem Producing reason generally has: 1, skin water shortage, and 80% the problem of property skin and skin water shortage have relationship;
2, lack nutrition (amino acid, microelement, ceramide lack);3, it is poor that maintenance ability is immunized;4, skin ecology is poor, grease point
Secrete that uneven, sebum film ecological disruption is unhealthy.
Have currently on the market and much declare replenishing water and preserving moisture, anti-inflammation detumescence or maintenance class product, effect is not apparent.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of cellular energy maintenance composition, the composition is enough skin
Comprehensive intensive moisturizing rapidly is provided, nutrition skin living is assigned, improves skin immunity, quick sterilization anti-inflammatory, detumescence healing;Have
Whitening, light spot, light tone, compact crease-resistant anti-wrinkle, the U.S. face of nourishing and other effects, in sunburn reparation, micro- whole, laser, the postoperative use of water light
It can quickly repair, be a kind of with very strong maintenance ability, tender with rear skin, the cellular energy maintenance for moistening beautiful produces
Product.
Technical scheme is as follows:
A kind of cellular energy remediation composition, the component containing following mass percent:
Amino acid humectant 0.2-5%,
Sodium Hyaluronate 0.005-0.2%,
Allantoin 0.5-1.5%,
Polyglutamic acid sodium 0.002-2%,
Compound biological enzyme 0.3-1.0%,
1,3- butanediol 1-3%,
Glycosylglycerol 0.001-2%,
Preservative 0.53-8%,
Close Luo Muye/stem extraction 0.001-1%,
Water complements to 100%.
Further, the compound biological enzyme includes plasmase, lysozyme, SOD(superoxide dismutase), paddy Guang
Sweet peptide peroxidase, catalase.Further, plasmase, lysozyme, SOD, paddy in the compound biological enzyme
The sweet peptide peroxidase of Guang, catalase mass parts ratio be 3-9:1-3:1-3:1-3:1-3.
Further, the preservative is sad glycine 0.01-1%, decoyl hydroximic acid 0.02-3%, 1,2- hexylene glycol
0.5-4%。
A kind of skin care compositions containing above-mentioned cellular energy remediation composition, the use of the cellular energy remediation composition
Amount is 1-100% by mass percentage.
Further, the dosage form of the skin care compositions is aqua, finish, lotion, any one in cream.
The allantoin of composition addition high concentration of the invention, the primary root problem of skin care is solved according to aquaporin theory
Moisturizing, rapid comprehensive intensive moisturizing, improves skin water content.Cooperate amino acid humectant, Sodium Hyaluronate, polyglutamic acid sodium
Etc. scientific compatibilities synergy realize long-acting moisturizing, maintenance skin problem.Compound bio enzyme component in the present invention passes through contact
Epithelial cell utilizes the metabolin H of cell itself2O, dehydrogenation collection oxygen, can be such that the oxygen content of cell is promoted rapidly, and can promote
Vesicle transport is carried out into cell, acute activation simultaneously promotes cell to be worked normally, and after the microcirculation of skin is got through, skin is clear
Except the channel of free radical and transport nutriment is more unobstructed, the active absorption of skin is solved the problems, such as at all.Autoimmunity activates vesica
Transhipment reparation problem can be such that the oxygen content of cell is promoted rapidly, and can promote Vesicle transport, when the microcirculation of skin is got through
Afterwards to promote epithelial cell to obtain repairing hyperplasia, a series of skin problems caused by solving because of cell water shortage anoxic.
Specific embodiment
The present invention will now be described in detail with reference to examples, and the examples are only preferred embodiments of the present invention,
It is not limitation of the invention.
Following table is 3 Example formulations tables (unit, %) of cellular energy maintenance composition of the present invention.The present invention is using this
The mixing of field routine and stirring technique are prepared, and do not illustrate herein.
Embodiment 1 | Embodiment 2 | Embodiment 3 | |
Amino Acid is protected Humectant | 0.2 | 3 | 5 |
It is transparent Matter acid Sodium | 0.2 | 0.01 | 0.005 |
Allantois Element | 0.5 | 1 | 1.5 |
Poly- paddy Propylhomoserin Sodium | 0.002 | 0.1 | 2 |
It is compound Biology Enzyme | 1.0, wherein plasmase, lysozyme, SOD, glutathione peroxidase, peroxide The mass parts ratio for changing hydrogen enzyme is 9:1:1: 1:1 | 0.6, wherein plasmase, lysozyme, SOD, glutathione peroxidase, peroxide The mass parts ratio for changing hydrogen enzyme is 3:2:1: 1:1 | 0.3, wherein plasmase, lysozyme, SOD, glutathione peroxidase, peroxide The mass parts ratio for changing hydrogen enzyme is 6:2:1: 1:1 |
1、3- Fourth two Alcohol | 1 | 2 | 3 |
Glycerol Glucose Glycosides | 2 | 0.05 | 0.001 |
Octanoic acid Sweet ammonia Acid | 0.01 | 0.6 | 1 |
Decoyl Hydroxyl oxime Acid | 0.02 | 1 | 3 |
1,2- Oneself two Alcohol | 0.5 | 2 | 4 |
Close sieve The wooden leaf/ Stem mentions Take object | 0.001 | 0.08 | 1 |
Go from Sub- water | Complement to 100 | Complement to 100 | Complement to 100 |
It is the experimental verification data to embodiment technical effect below.
One, quick sterilization, anti-inflammation detumescence test
1, test method:
4 groups are set, and every group of 10 people, A group and B group are to be the voluntary tester of cutting eyelid-slicing operation, and C group and D group are to do
The voluntary tester of water light art.A group and the postoperative horse back of C group smear the cellular energy maintenance composition of embodiment 1, and B group and D group are pressed
Postoperative conventional means (smearing medicinal alcohol or physiological saline) carry out anti-inflammation and sterilization processing, observing effect.
2, test result see the table below:
Group | As a result |
A | Wound convergence in 5 minutes, no oozing of blood after smearing;30 minutes --- in 6 hours, anti-inflammation detumescence, wound convergence is without oozing of blood.Eyes can normally make With wound is without special care and covers protection;1-6th day, no oozing of blood no inflammation itch, oedema, no incrustation might without formation scar. Lasting to use, no inflammation is without oedema after postoperative 6 hours |
B | Eyelid is all red and swollen state after hour after 30 minutes, the slight oozing of blood of wound, eyes edema pain can not normal use, wound needs special shield Reason and covering protection, there is incrustation in the wound beginning after 3 days, and itch oedema is reduced swelling successively after about 6--15 days |
C | Without oozing of blood after sprinkling;10-30 minutes wound convergences;Wound reparation is without sharp trace within 1--3 hours. |
D | Water laser accunputure is postoperative smeared with physiological saline after, wound convergence, which slowly examines, slight oozing of blood in 1 hour, wound has scabies within 3-6 hours Itch, has examined postoperative pinprick trace |
As it can be seen that cellular energy maintenance liquid of the present invention has the effect of quick sterilization, anti-inflammation detumescence.
Two, maintenance aptitude tests
1, test method:
(1) epifolliculitis reparation: epifolliculitis patient caused by 40 hormone face sequelae is found, is randomly divided into A, B, C, D tetra- small
Group, every group of 10 people smear cellular energy maintenance composition, certain medical ointment for treating epifolliculitis of embodiment 1-3, respectively
Primary, continuous to smear 6 days, observation effect is smeared to be each in the morning, afternoon and evening.
(2) sunburn is repaired: 40 voluntary testers are found, are randomly divided into tetra- groups of E, F, G, H, every group of 10 people, in
Outdoor activities a few hours, after the solarization for receiving same degree, skin of face is cleaned, smears embodiment 1 respectively, embodiment 2, implements
Example 3 and certain it is commercially available have effects that the product of after-sun recovery, daily in the morning, afternoon and evening it is each smear it is primary, about 1 gram every time, continuous smearing 3 days,
Observe repairing effect.
2, test result see the table below:
Group | As a result |
A | Crew's epifolliculitis is substantially reduced after 6 days, and readme has restored seventy percent or more |
B | Crew's epifolliculitis is substantially reduced after 6 days, and readme has restored seventy percent or more |
C | Crew's epifolliculitis is substantially reduced after 6 days, and readme has restored seventy percent or more |
D | Crew's epifolliculitis symptom is not obviously improved after 6 days |
E | Rubescent symptom completely disappears, skin smooth is flexible, back to normal |
F | Rubescent symptom completely disappears, skin smooth is flexible, back to normal |
G | Rubescent symptom completely disappears, skin smooth is flexible, back to normal |
H | Skin is still rubescent, there is husking |
As it can be seen that cellular energy maintenance liquid of the present invention has apparent cell repair effect.
Three, the test of whitening, light spot, light tone, compact crease-resistant anti-wrinkle, the U.S. face of nourishing and other effects
1, test item: dermal melanin content, skin whiteness, skin brightness, moisture content, water loss, glossiness, skin
Skin elasticity
2, test equipment: CK MPA580 skinanalysis apparatus, Mexameter dermal melanin and ferroheme test probe,
Colormeter skin color test probe, Corneometer moisture measurement are popped one's head in, Tewameter water loss is popped one's head in,
Glossymeter glossiness test probe, Cutometer skin elasticity test probe.
3, study subject: qualified volunteer is screened, selects face as test position.According to the Chardon method of dividision into groups, basis
ITA ° of skin brightness between II ~ IV grade.(certain is commercially available with moisturizing guarantor for embodiment 1, embodiment 2, embodiment/3, comparative example
The product of wet, whitening nourishing and other effects) each 20 subjects of each group.
4, test period: test period is 28 days, is surveyed using instrument within the 14th, 28 day after 1 day and use before using sample
Try indices.In test after use, volunteer cannot smear sample on the day of test, need to reuse after the completion of testing
Sample.
5, sample uses: test first 1 week is the elution phase, and subject uses the basic moisturizing without any active matter during this
Water and moisturizer.Other whitening products cannot be used dduring test.Use sample, every morning, evening within subject continuous 28 days
On sleep before wash one's face after face smear sample, applying amount is about 0.25g.Test melanin content, whiteness, brightness are necks
It is used as own control.
6, it test process: is acquired using preceding data: before test, in the constant temperature that temperature is 24 ± 1 DEG C, humidity is 55 ± 5%RH
It sits quietly in humidity room 20 minutes.It is surveyed with Colormeter skin color test probe, Mexameter dermal melanin and ferroheme
Probe header, Corneometer moisture measurement probe, Tewameter water loss probe, the test of Glossymeter glossiness are visited
Head, Cutometer skin elasticity test probe carry out the acquisition using preceding data in test position.Each survey to each test position
Pilot loop test 4 times, it is averaged data before the use as corresponding position.
7, the 7th, 14,28 day data acquire after use, and step is acquired with using preceding data.
8, test result
(1) dermal melanin changes of contents rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | -12.03% | -12.56% | -12.27% | -6.62% |
14 | -16.55% | -15.34% | -17.52% | -8.52% |
28 | -19.74% | -18.95% | -19.55% | -10.26% |
(2) skin whiteness change rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | 1.61% | 1.55% | 1.60% | 0.73% |
14 | 1.66% | 1.62% | 1.66% | 0.89% |
28 | 1.92% | 1.79% | 1.88% | 1.54% |
(3) skin brightness change rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | 8.92 | 8.74 | 8.62 | 5.98 |
14 | 15.45 | 14.85 | 15.64 | 8.94 |
28 | 18.66 | 19.68 | 18.55 | 11.21 |
(4) moisture content change rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | 25.56% | 25.54% | 26.25% | 18.85% |
14 | 33.62% | 32.22% | 33.54% | 22.44% |
28 | 44.55% | 41.25% | 39.94% | 25.45% |
(5) water loss change rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | -12.25 | -12.54 | -12.35 | -9.45 |
14 | -14.28 | -14.55 | -14.84 | -11.15 |
28 | -16.69 | -16.46 | -17.31 | -12.22 |
(6) glossiness change rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | 7.15 | 7.68 | 7.58 | 4.84 |
14 | 7.83 | 8.25 | 8.71 | 7.58 |
28 | 13.45 | 12.25 | 12.97 | 9.55 |
(7) skin elasticity change rate:
Time (day) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example |
7 | 4.49 | 4.54 | 4.70 | 3.12 |
14 | 6.76 | 5.85 | 5.64 | 4.41 |
28 | 7.55 | 7.14 | 7.62 | 4.53 |
From the dermal melanin content of the test of embodiment and comparative example, skin whiteness, skin brightness, moisture content, moisture
Loss, glossiness, in skin elasticity test result as can be seen that the whitening of embodiment, which highlights composition tool, is significantly reduced skin
Skin melanin content improves whitening skin degree and brightness, and increases skin moisture content, enhances skin barrier function, mentions
The effect of high skin shine.
By above-mentioned efficacy test result it is found that the present invention can provide rapid comprehensive intensive moisturizing for skin, improve
Skin water content, replenishing water and preserving moisture repair antiallergic anti-inflammatory, assign nutrition skin living, improve skin immunity, disappear with more quick sterilization
Scorching, detumescence healing;Whitening, light spot, light tone, compact crease-resistant anti-wrinkle, the U.S. face of nourishing and other effects, are repaired in sunburn, micro- whole, laser,
The postoperative use of water light can be repaired quickly, be a kind of with very strong maintenance ability, moisten beautiful cell tender with rear skin
Energy maintenance product.
Claims (6)
1. a kind of cellular energy remediation composition, which is characterized in that the component containing following mass percent:
Amino acid humectant 0.2-5%,
Sodium Hyaluronate 0.005-0.2%,
Allantoin 0.5-1.5%,
Polyglutamic acid sodium 0.002-2%,
Compound biological enzyme 0.3-1.0%,
1,3- butanediol 1-3%,
Glycosylglycerol 0.001-2%,
Preservative 0.53-8%,
Close Luo Muye/stem extraction 0.001-1%,
Water complements to 100%.
2. cellular energy remediation composition according to claim 1, which is characterized in that the compound biological enzyme includes fiber
Protease, lysozyme, SOD, glutathione peroxidase, catalase.
3. cellular energy remediation composition according to claim 2, which is characterized in that fiber egg in the compound biological enzyme
White enzyme, lysozyme, SOD, glutathione peroxidase, catalase mass parts ratio be 3-9:1-3:1-3:1-3:1-
3。
4. cellular energy remediation composition according to claim 1, which is characterized in that the preservative is sad glycine
0.01-1%, decoyl hydroximic acid 0.02-3%, 1,2- hexylene glycol 0.5-4%.
5. a kind of skin care compositions containing cellular energy remediation composition described in claim 1-4 any one, the cell
The dosage of energy remediation composition is 1-100% by mass percentage.
6. skin care compositions according to claim 5, it is characterised in that: the dosage form of the skin care compositions is aqua, oil
Agent, lotion, any one in cream.
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CN201910476703.4A CN110123695B (en) | 2019-06-03 | 2019-06-03 | Cell energy restoration composition |
PCT/CN2019/119823 WO2020244167A1 (en) | 2019-06-03 | 2019-11-21 | Cellular energy repair composition |
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CN201910476703.4A CN110123695B (en) | 2019-06-03 | 2019-06-03 | Cell energy restoration composition |
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CN110123695B CN110123695B (en) | 2021-04-27 |
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Cited By (3)
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WO2020244166A1 (en) * | 2019-06-05 | 2020-12-10 | 惠州学院 | Multi-biological enzyme medical restoring face mask and preparation method thereof |
CN113633563A (en) * | 2021-08-12 | 2021-11-12 | 广州市中科医美生物科技有限公司 | Ecological sun-proof light-permeable isolation repairing emulsion and preparation method thereof |
CN113730560A (en) * | 2021-08-06 | 2021-12-03 | 广州市中科医美生物科技有限公司 | Spraying eye washing liquid for brightening and soothing bright eyes and preparation method thereof |
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