CN110092830B - 用于诊断和治疗结核分枝杆菌感染的抗lam和抗pim6/lam单克隆抗体 - Google Patents

用于诊断和治疗结核分枝杆菌感染的抗lam和抗pim6/lam单克隆抗体 Download PDF

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CN110092830B
CN110092830B CN201910291444.8A CN201910291444A CN110092830B CN 110092830 B CN110092830 B CN 110092830B CN 201910291444 A CN201910291444 A CN 201910291444A CN 110092830 B CN110092830 B CN 110092830B
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lam
antibody
seq
variable region
chain variable
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CN110092830A (zh
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A·平特
A·超德瑞
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Rutgers State University of New Jersey
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
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    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56933Mycoplasma
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • AHUMAN NECESSITIES
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    • C07K2317/00Immunoglobulins specific features
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CN201910291444.8A 2016-02-10 2017-02-01 用于诊断和治疗结核分枝杆菌感染的抗lam和抗pim6/lam单克隆抗体 Active CN110092830B (zh)

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CN201910291444.8A CN110092830B (zh) 2016-02-10 2017-02-01 用于诊断和治疗结核分枝杆菌感染的抗lam和抗pim6/lam单克隆抗体

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US201662293406P 2016-02-10 2016-02-10
US62/293,406 2016-02-10
CN201910291444.8A CN110092830B (zh) 2016-02-10 2017-02-01 用于诊断和治疗结核分枝杆菌感染的抗lam和抗pim6/lam单克隆抗体
PCT/US2017/016058 WO2017139153A1 (en) 2016-02-10 2017-02-01 Novel anti-lam and anti-pim6/lam monoclonal antibodies for diagnosis and treatment of mycobacterium tuberculosis infections
CN201780017369.5A CN109073649A (zh) 2016-02-10 2017-02-01 用于诊断和治疗结核分枝杆菌感染的新颖抗lam和抗pim6/lam单克隆抗体

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CN201780017369.5A Pending CN109073649A (zh) 2016-02-10 2017-02-01 用于诊断和治疗结核分枝杆菌感染的新颖抗lam和抗pim6/lam单克隆抗体

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AU (2) AU2017218415B2 (enExample)
CA (1) CA3013904C (enExample)
ES (1) ES2970828T3 (enExample)
RU (1) RU2732502C2 (enExample)
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ZA (3) ZA201805990B (enExample)

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CN113480659B (zh) * 2021-06-30 2022-10-21 迪比康(上海)生物科技有限公司 人源抗结核分枝杆菌复合群lam单克隆抗体及其制备和应用
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CN117247450B (zh) * 2023-10-10 2025-02-25 广州市雷德生物科技有限公司 一种lam抗体及其应用
CN118178640B (zh) * 2024-03-08 2025-11-21 中国农业大学 含有牛分枝杆菌表面多糖的佐剂及其应用

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AU2024205286A1 (en) 2024-08-22
US20200316199A1 (en) 2020-10-08
EP3414573B1 (en) 2023-11-08
EP4299072A3 (en) 2024-05-01
JP2021105034A (ja) 2021-07-26
RU2732502C2 (ru) 2020-09-18
ZA201805990B (en) 2023-01-25
BR112018016226A2 (pt) 2019-01-02
US11273220B2 (en) 2022-03-15
AU2017218415A1 (en) 2018-09-27
JP2019506412A (ja) 2019-03-07
WO2017139153A1 (en) 2017-08-17
ES2970828T3 (es) 2024-05-30
US20220168420A1 (en) 2022-06-02
ZA202307912B (en) 2025-11-26
EP3414573A1 (en) 2018-12-19
AU2017218415B2 (en) 2024-05-02
JP7316685B2 (ja) 2023-07-28
US12303562B2 (en) 2025-05-20
CN110092830A (zh) 2019-08-06
RU2018131622A3 (enExample) 2020-04-13
US10729771B2 (en) 2020-08-04
ZA202209045B (en) 2023-12-20
EP4299072A2 (en) 2024-01-03
US20240307535A1 (en) 2024-09-19
US20190038747A1 (en) 2019-02-07
CN109073649A (zh) 2018-12-21
CA3013904A1 (en) 2017-08-17
CA3013904C (en) 2023-12-12
EP3414573A4 (en) 2019-10-30
JP2024174883A (ja) 2024-12-17

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