RU2018131622A3 - - Google Patents
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- Publication number
- RU2018131622A3 RU2018131622A3 RU2018131622A RU2018131622A RU2018131622A3 RU 2018131622 A3 RU2018131622 A3 RU 2018131622A3 RU 2018131622 A RU2018131622 A RU 2018131622A RU 2018131622 A RU2018131622 A RU 2018131622A RU 2018131622 A3 RU2018131622 A3 RU 2018131622A3
- Authority
- RU
- Russia
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56933—Mycoplasma
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/02—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/44—Multiple drug resistance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662293406P | 2016-02-10 | 2016-02-10 | |
| US62/293,406 | 2016-02-10 | ||
| PCT/US2017/016058 WO2017139153A1 (en) | 2016-02-10 | 2017-02-01 | Novel anti-lam and anti-pim6/lam monoclonal antibodies for diagnosis and treatment of mycobacterium tuberculosis infections |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2018131622A RU2018131622A (ru) | 2020-03-10 |
| RU2018131622A3 true RU2018131622A3 (enExample) | 2020-04-13 |
| RU2732502C2 RU2732502C2 (ru) | 2020-09-18 |
Family
ID=59563993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018131622A RU2732502C2 (ru) | 2016-02-10 | 2017-02-01 | Новые моноклональные антитела к LAM и PIM6/LAM для диагностики и лечения инфекций, вызванных Mycobacterium tuberculosis |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10729771B2 (enExample) |
| EP (2) | EP4299072A3 (enExample) |
| JP (4) | JP2019506412A (enExample) |
| CN (2) | CN109073649A (enExample) |
| AU (2) | AU2017218415B2 (enExample) |
| CA (1) | CA3013904C (enExample) |
| ES (1) | ES2970828T3 (enExample) |
| RU (1) | RU2732502C2 (enExample) |
| WO (1) | WO2017139153A1 (enExample) |
| ZA (3) | ZA201805990B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017218415B2 (en) | 2016-02-10 | 2024-05-02 | Rutgers, The State University Of New Jersey | Novel anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of mycobacterium tuberculosis infections |
| US10830760B2 (en) * | 2017-12-20 | 2020-11-10 | General Electric Company | Device for rapid detection of tuberculosis-lipoarabinomannan (TB-LAM) with enhanced sensitivity |
| WO2019186486A1 (en) * | 2018-03-29 | 2019-10-03 | Foundation Of Innovative New Diagnostics | Antibody or antibody combination and method using same for detection of an antigen related to mycobacterium in a urine sample of a subject |
| WO2020018806A1 (en) | 2018-07-19 | 2020-01-23 | Rutgers, The State University Of New Jersey | Methods for dual detection and differentiation of infection by mycobactierum tuberculosis complex and nontuberculous mycobacteria |
| WO2020045625A1 (ja) | 2018-08-31 | 2020-03-05 | 富士フイルム株式会社 | イムノクロマトグラフキットおよび結核菌の検出方法 |
| WO2021065144A1 (ja) | 2019-09-30 | 2021-04-08 | 富士フイルム株式会社 | イムノクロマトグラフィー |
| CN114341639A (zh) | 2019-09-30 | 2022-04-12 | 富士胶片株式会社 | 免疫检查方法及浓缩用夹具 |
| CN111337665A (zh) * | 2020-01-16 | 2020-06-26 | 卢氏实验室公司 | 一种用于检测肺结核感染的免疫层析试纸条及其制备方法 |
| WO2021153127A1 (ja) | 2020-01-31 | 2021-08-05 | 富士フイルム株式会社 | 免疫検査方法 |
| JP7257556B2 (ja) | 2020-01-31 | 2023-04-13 | 富士フイルム株式会社 | イムノクロマトグラフィー |
| JP7350100B2 (ja) | 2020-01-31 | 2023-09-25 | 富士フイルム株式会社 | イムノクロマトグラフィー |
| CN111153992A (zh) * | 2020-02-21 | 2020-05-15 | 首都医科大学附属北京胸科医院 | 结核分枝杆菌lam的单克隆抗体及其用途 |
| WO2022011001A1 (en) * | 2020-07-07 | 2022-01-13 | The Regents Of The University Of California | Method for antigen detection from direct clinical samples |
| EP4192429A4 (en) * | 2020-08-05 | 2024-10-09 | The Administrators of The Tulane Educational Fund | METHOD FOR DETECTING TB IN BODY FLUID SAMPLES |
| EP4212873A4 (en) | 2020-09-11 | 2024-06-05 | FUJIFILM Corporation | CONCENTRATION DEVICE, METHOD FOR CONCENTRATING A SAMPLE SOLUTION, METHOD FOR TESTING A SAMPLE SOLUTION AND TEST KIT |
| WO2022054524A1 (ja) | 2020-09-11 | 2022-03-17 | 富士フイルム株式会社 | 濃縮デバイス、検体液の濃縮方法、検体液の検査方法、及び、検査キット |
| CN116171378A (zh) | 2020-09-11 | 2023-05-26 | 富士胶片株式会社 | 被检体液的浓缩方法、及被检体液的检查方法 |
| WO2022081716A1 (en) * | 2020-10-13 | 2022-04-21 | Accubit LLC - Biotechnology | Methods of treating iga nephropathy with thiol-containing molecules |
| EP4263598A4 (en) * | 2020-12-15 | 2025-04-09 | Albert Einstein College of Medicine | High-affinity mycobacterium tuberculosis capsule-specific human monoclonal antibodies |
| CN113480659B (zh) * | 2021-06-30 | 2022-10-21 | 迪比康(上海)生物科技有限公司 | 人源抗结核分枝杆菌复合群lam单克隆抗体及其制备和应用 |
| CN114984870A (zh) * | 2022-03-15 | 2022-09-02 | 齐欣 | 一种重组蛋白质微球及其制备方法和应用 |
| CN117247450B (zh) * | 2023-10-10 | 2025-02-25 | 广州市雷德生物科技有限公司 | 一种lam抗体及其应用 |
| CN118178640B (zh) * | 2024-03-08 | 2025-11-21 | 中国农业大学 | 含有牛分枝杆菌表面多糖的佐剂及其应用 |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| US4636524A (en) | 1984-12-06 | 1987-01-13 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
| JPH09505308A (ja) | 1993-11-19 | 1997-05-27 | アルカーミズ・コントロールド・セラピューティクス・インコーポレイテッド・トゥー | 生物学的活性剤を含有する生分解性微粒子の製造 |
| US6656508B2 (en) | 1997-04-17 | 2003-12-02 | Amgen Inc. | Sustained-release alginate gels |
| US20010007660A1 (en) * | 1997-06-04 | 2001-07-12 | Aharona Glatman-Freedman | Methods of treating and protecting against tuberculosis using a monoclonal antibody selective for mycobacterium tuberculosis |
| EP1028746B1 (en) | 1997-11-07 | 2003-02-26 | Chiron Corporation | Method for producing igf-i sustained-release formulations |
| US6541033B1 (en) | 1998-06-30 | 2003-04-01 | Amgen Inc. | Thermosensitive biodegradable hydrogels for sustained delivery of leptin |
| US6451346B1 (en) | 1998-12-23 | 2002-09-17 | Amgen Inc | Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents |
| US6953593B2 (en) | 2000-02-01 | 2005-10-11 | Lipoprotein Technologies, Inc. | Sustained-release microencapsulated delivery system |
| WO2002085335A1 (en) | 2001-04-18 | 2002-10-31 | Nostrum Pharmaceuticals Inc. | A novel coating for a sustained release pharmaceutical composition |
| US7063725B2 (en) | 2002-10-21 | 2006-06-20 | Sdgi Holdings, Inc. | Systems and techniques for restoring and maintaining intervertebral anatomy |
| CA2437639C (en) | 2003-08-11 | 2016-07-05 | Valera Pharmaceuticals, Inc. | Long term drug delivery devices with polyurethane based polymers and their manufacture |
| US20050187631A1 (en) | 2004-01-27 | 2005-08-25 | Sdgi Holdings, Inc. | Prosthetic device |
| UA92721C2 (ru) * | 2004-07-20 | 2010-12-10 | Чемоджен, Инк. | Обогащенная популяция антител, высокоспецифических к антигену поверхностного полисахарида липоарабиноманана (lam) микобактерии, способ выявления микобактериальной инфекции в образце и набор для выявления микобактериальной инфекции |
| CN101216491B (zh) * | 2008-01-08 | 2012-06-06 | 广州益善生物技术有限公司 | 结核分枝杆菌检测液相芯片及其制备方法 |
| EP2242836B1 (en) * | 2008-01-28 | 2015-05-20 | Thomas Jefferson University | Method of making hybrid cells that express useful antibodies |
| AU2009294414A1 (en) | 2008-09-19 | 2010-03-25 | Medimmune Llc | Antibodies directed to CD105 and uses thereof |
| WO2011013698A1 (ja) * | 2009-07-29 | 2011-02-03 | 東亞合成株式会社 | キャリアペプチドフラグメント及びその利用 |
| US9315566B2 (en) * | 2011-01-24 | 2016-04-19 | National University Of Singapore | Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins |
| DK2821415T3 (da) * | 2012-02-29 | 2021-04-26 | Otsuka Pharma Co Ltd | Antistof mod anti-lipoarabinomannan og immunoassay til syrefast bacillær infektion under anvendelse af antistoffet |
| JO3462B1 (ar) * | 2012-08-22 | 2020-07-05 | Regeneron Pharma | أجسام مضادة بشرية تجاه gfr?3 وطرق لاستخدامها |
| AU2017218415B2 (en) | 2016-02-10 | 2024-05-02 | Rutgers, The State University Of New Jersey | Novel anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of mycobacterium tuberculosis infections |
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2017
- 2017-02-01 AU AU2017218415A patent/AU2017218415B2/en active Active
- 2017-02-01 WO PCT/US2017/016058 patent/WO2017139153A1/en not_active Ceased
- 2017-02-01 US US16/076,971 patent/US10729771B2/en active Active
- 2017-02-01 ES ES17750586T patent/ES2970828T3/es active Active
- 2017-02-01 EP EP23208073.9A patent/EP4299072A3/en active Pending
- 2017-02-01 CA CA3013904A patent/CA3013904C/en active Active
- 2017-02-01 CN CN201780017369.5A patent/CN109073649A/zh active Pending
- 2017-02-01 JP JP2018541386A patent/JP2019506412A/ja active Pending
- 2017-02-01 CN CN201910291444.8A patent/CN110092830B/zh active Active
- 2017-02-01 EP EP17750586.4A patent/EP3414573B1/en active Active
- 2017-02-01 RU RU2018131622A patent/RU2732502C2/ru active
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2018
- 2018-09-06 ZA ZA2018/05990A patent/ZA201805990B/en unknown
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2020
- 2020-06-24 US US16/910,621 patent/US11273220B2/en active Active
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2021
- 2021-04-02 JP JP2021063301A patent/JP7316685B2/ja active Active
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2022
- 2022-02-17 US US17/651,523 patent/US11707525B2/en active Active
- 2022-08-12 ZA ZA2022/09045A patent/ZA202209045B/en unknown
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2023
- 2023-03-01 JP JP2023031004A patent/JP2023075196A/ja active Pending
- 2023-06-15 US US18/335,489 patent/US12303562B2/en active Active
- 2023-08-15 ZA ZA2023/07912A patent/ZA202307912B/en unknown
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2024
- 2024-08-01 AU AU2024205286A patent/AU2024205286A1/en active Pending
- 2024-08-19 JP JP2024137825A patent/JP2024174883A/ja active Pending