CN110074891A - Irradiation test rat fixing device - Google Patents

Irradiation test rat fixing device Download PDF

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Publication number
CN110074891A
CN110074891A CN201810072790.2A CN201810072790A CN110074891A CN 110074891 A CN110074891 A CN 110074891A CN 201810072790 A CN201810072790 A CN 201810072790A CN 110074891 A CN110074891 A CN 110074891A
Authority
CN
China
Prior art keywords
pedestal
fixed
snap
fixing device
gauge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810072790.2A
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Chinese (zh)
Inventor
王新钢
李曙芳
许文黎
刘梦雅
安全
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
China Institute for Radiation Protection
Original Assignee
China Institute for Radiation Protection
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by China Institute for Radiation Protection filed Critical China Institute for Radiation Protection
Priority to CN201810072790.2A priority Critical patent/CN110074891A/en
Publication of CN110074891A publication Critical patent/CN110074891A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/003Appliances for supporting or fettering animals for operative purposes with head or neck restraining means

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Measurement Of Radiation (AREA)

Abstract

The present invention relates to irradiation test rat fixing devices, it includes the open cuboid pedestal (6) in top and the fixed module that is mounted in pedestal (6), the groove (1) for fixed test rat head is provided on the end plate of the pedestal (6), the fixed module includes two groups of vertical card slots pair and the snap-gauge (2) for being slidably mounted on every group of card slot centering, two card slots (4) of every group of card slot centering are accordingly located on the inner wall of pedestal (6) two sides, the bottom end of the snap-gauge (2) is recessed arcuate structure, the edge of the arcuate structure has in one's ear (3).Present apparatus structure is simple, easy to operate, low manufacture cost, is conducive to produce in batches;The present apparatus, which can be used, is made the lesser clear hard plastics of radiation absorption, guarantees the accuracy to the fixed safety and stability of rat and exposure dose, and the disinfection capable of washing of all components is convenient to utilize again.

Description

Irradiation test rat fixing device
Technical field
The invention belongs to irradiation test equipment technical fields, and in particular to irradiation test rat fixing device.
Background technique
As atomic energy is in the popularization and application of all fields of national economy such as national defence, industry, agricultural, medical treatment, science and technology, nuclear energy exists While promoting the well-being of mankind, serious nuclear radiation crisis also is brought to the world today, is brought sternly to the health and safety of the mankind High challenge.In terms of medical treatment, radiotherapy is still malignant tumour and some carcinoid critical treatment means, but swollen Generated free radical, active oxygen can the serious damages of normal tissue cell generation after receiving doses irradiation for oncocyte Wound, it is this to act on while depositing to the local instantaneity lethal effect of tumour cell and to the histiocytic delay injuring in the whole body , as radiotherapy side effect be also restrict oncotherapy effect " bottleneck ".More efficiently radiation protection means are found just to show Must be further important, it is Radiation Medicine problem anxious to be resolved, therefore scientific research personnel needs to carry out a large amount of zoopery to find Suitable solution.
Summary of the invention
In view of the deficiencies in the prior art, the object of the present invention is to provide a kind of irradiation test rat fixing device, The apparatus structure is simple, low manufacture cost, and convenient for operation.
To achieve the above objectives, the technical solution adopted by the present invention is that: irradiation test rat fixing device, including top are spacious The fixed module of the cuboid pedestal opened and installation in the base is provided on the end plate of the pedestal big for fixed test The groove on mouse head, the fixed module include two groups of vertical card slots pair and the snap-gauge for being slidably mounted on every group of card slot centering, Two card slots of every group of card slot centering are accordingly located on the inner wall of pedestal two sides, and the bottom end of the snap-gauge is recessed arc knot The edge of structure, the arcuate structure has in one's ear.
Further, the number of the fixed module is two, and two fixed modules are along the length direction pair of the pedestal Claim setting.
Further, the pedestal is equipped with two fixed plates being located between two fixed modules, and two fixed plates It is accordingly mounted on the inner wall of pedestal two sides, vertical U-shaped fixing groove is provided in the fixed plate.
Further, the pedestal, fixed module, fixed plate and snap-gauge be respectively the pedestal made of clear hard plastics, Fixed module, fixed plate and snap-gauge.
Compared with prior art, the invention has the following advantages that
The first, present apparatus structure is simple, easy to operate, low manufacture cost, is conducive to produce in batches.
The second, the present apparatus, which can be used, is made the lesser clear hard plastics of radiation absorption, and all components are capable of washing to disappear Poison, it is convenient to utilize again;Also, the cavity of device obtained have smooth inner surface, no sharp projection, the body of rat, There are respective fixed part in head and tail portion, guarantee the safety and stability fixed to rat;Meanwhile both facilitating observation dynamic Object anesthesia in turn ensures that experimental animal receives the accuracy of exposure dose to take corresponding measure to protect animal in time.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of irradiation test rat fixing device provided by the invention.
Specific embodiment
Present invention will be further described below with reference to the accompanying drawings and specific embodiments.
As shown in Figure 1, irradiation test rat fixing device provided by the invention includes the open cuboid pedestal 6 in top And it is mounted on the fixed module in pedestal 6, the groove 1 for fixed test rat head is provided on the end plate of the pedestal 6, The fixed module includes two groups of vertical card slots pair and the snap-gauge 2 for being slidably mounted on every group of card slot centering, every group of card slot centering Two card slots 4 be accordingly located on 6 two sides inner wall of pedestal, the bottom end of the snap-gauge 2 is recessed arcuate structure, the arc The edge of structure is in one's ear 3.
In the preferred embodiments of the disclosure, the number of the fixed module is two, and two fixed modules Length direction along the pedestal 6 is symmetrical arranged.Correspondingly, the pedestal 6 is equipped with two be located between two fixed modules A fixed plate 5, and two fixed plates 5 are accordingly mounted on 6 two sides inner wall of pedestal is provided with vertical U-shaped in the fixed plate 5 Fixing groove 5-1, the tail portion for fixed test rat.
As a kind of embodiment of the invention, (cavity) length of the present apparatus can be 37cm, and wide can be 7cm, Gao Ke Think 5cm.
In the present invention, the pedestal 6, fixed module, fixed plate 5 and snap-gauge 2 can be to be made of clear hard plastics.This Kind hard transparent plastic is smaller to radiation ray absorbed dose, almost can be ignored;Meanwhile using transparent plastics material, Facilitate the state of the real-time observation experiment animal of experimenter;Also, the smooth no protrusion of the cavity inner wall of this device, to avoid The wound that may cause when fixed rat.
In addition, the shape of groove 1 is preferably adapted with the neck profile of rat, the arcuate structure of 2 bottom end of snap-gauge and in one's ear 3 Shape preferably with the abdomen profile of rat be adapted.
The method that irradiation test is carried out using the present apparatus below in conjunction with Fig. 1 brief description.
Before experiment, by rat anesthesia, irradiation field is drawn;
Then, four sliding jaws 2 for removing any fixed module of the present apparatus, rat is put into the cavity of pedestal, is made Rat head is placed in groove 1, and snap-gauge 2 is gently caught in card slot 4, makes the abutting rat abdomen in one's ear of snap-gauge 2,2 top of snap-gauge Can be suitably fixed with adhesive tape, while it being folded back into a part after rat tails are placed on U-shaped fixing groove 5, it can be suitably fixed with adhesive tape;
Then, after calculating ource-skin Distance, by the present apparatus that four are mounted with rat be placed on away from the fixed position east in source, west, south, In four positive directions in north, orientation between attention device is highly consistent.In addition to irradiated site, remaining position of rat is used Lead brick blocks, and observes animal life sign, and no special circumstances start to be irradiated;
After irradiation, the snap-gauge 2 of fixed rat is gently removed, rat is put back into cage tool, pays attention to keeping rats breathing Unobstructed, the end experimental implementation in road.
Structure of the present invention is not limited to embodiment described in specific embodiment, and those skilled in the art are according to this The technical solution of invention obtains other embodiments, also belongs to the scope of the technical innovation of the present invention.

Claims (4)

1. irradiation test rat fixing device, which is characterized in that the irradiation test rat fixing device includes that top is open Cuboid pedestal (6) and the fixed module being mounted in pedestal (6) are provided with for fixing on the end plate of the pedestal (6) The groove (1) of rat head is tested, the fixed module includes two groups of vertical card slots pair and is slidably mounted on every group of card slot pair In snap-gauge (2), two card slots (4) of every group of card slot centering are accordingly located on the inner wall of pedestal (6) two sides, the snap-gauge (2) Bottom end be recessed arcuate structure, the edge of the arcuate structure has in one's ear (3).
2. irradiation test rat fixing device according to claim 1, which is characterized in that the number of the fixed module is Two, and two fixed modules are symmetrical arranged along the length direction of the pedestal (6).
3. irradiation test rat fixing device according to claim 2, which is characterized in that the pedestal (6) is equipped with position Two fixed plates (5) between two fixed modules, and two fixed plates (5) are accordingly mounted on pedestal (6) two sides inner wall On, vertical U-shaped fixing groove (5-1) is provided on the fixed plate (5).
4. irradiation test rat fixing device according to claim 1 to 3, which is characterized in that the pedestal (6) is consolidated Cover half block, fixed plate (5) and snap-gauge (2) are the pedestal made of clear hard plastics, fixed module, fixed plate and card respectively Plate.
CN201810072790.2A 2018-01-25 2018-01-25 Irradiation test rat fixing device Pending CN110074891A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810072790.2A CN110074891A (en) 2018-01-25 2018-01-25 Irradiation test rat fixing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810072790.2A CN110074891A (en) 2018-01-25 2018-01-25 Irradiation test rat fixing device

Publications (1)

Publication Number Publication Date
CN110074891A true CN110074891A (en) 2019-08-02

Family

ID=67412043

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810072790.2A Pending CN110074891A (en) 2018-01-25 2018-01-25 Irradiation test rat fixing device

Country Status (1)

Country Link
CN (1) CN110074891A (en)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100072873A (en) * 2008-12-22 2010-07-01 울산대학교 산학협력단 Apparatus fixing the position and location of mouse for imaging acquisition with multiple modalities
CN201578393U (en) * 2009-12-28 2010-09-15 夏博文 Clamp holder for animal experiments
US20110083614A1 (en) * 2009-10-08 2011-04-14 Massachusetts Institute Of Technology Compliant Holder Device for Animal Imaging and Surgery
CN202568522U (en) * 2012-05-25 2012-12-05 吉林大学 Mouse fixing device for radiation experiment and tail intravenous injection
CN103565537A (en) * 2012-07-23 2014-02-12 中国辐射防护研究院 Mouse irradiation disc fixing device
CN203693830U (en) * 2014-02-13 2014-07-09 苏州工业园区唯亭姑秀实验动物设备厂 Rat and mouse fixator
CN203970607U (en) * 2014-07-23 2014-12-03 浙江省肿瘤医院 Radiation biological experiment flip-shell fixed support
CN203988470U (en) * 2014-07-23 2014-12-10 浙江省肿瘤医院 Radiation biological experiment blade inserting fixed support
CN205494070U (en) * 2016-03-18 2016-08-24 中国人民解放军成都军区疾病预防控制中心 Experimental animals retaining frame
CN106725977A (en) * 2016-12-28 2017-05-31 中国人民解放军军事医学科学院放射与辐射医学研究所 Occupational exposure to magnetic fields experiment rat single cage fixing device

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100072873A (en) * 2008-12-22 2010-07-01 울산대학교 산학협력단 Apparatus fixing the position and location of mouse for imaging acquisition with multiple modalities
US20110083614A1 (en) * 2009-10-08 2011-04-14 Massachusetts Institute Of Technology Compliant Holder Device for Animal Imaging and Surgery
CN201578393U (en) * 2009-12-28 2010-09-15 夏博文 Clamp holder for animal experiments
CN202568522U (en) * 2012-05-25 2012-12-05 吉林大学 Mouse fixing device for radiation experiment and tail intravenous injection
CN103565537A (en) * 2012-07-23 2014-02-12 中国辐射防护研究院 Mouse irradiation disc fixing device
CN203693830U (en) * 2014-02-13 2014-07-09 苏州工业园区唯亭姑秀实验动物设备厂 Rat and mouse fixator
CN203970607U (en) * 2014-07-23 2014-12-03 浙江省肿瘤医院 Radiation biological experiment flip-shell fixed support
CN203988470U (en) * 2014-07-23 2014-12-10 浙江省肿瘤医院 Radiation biological experiment blade inserting fixed support
CN205494070U (en) * 2016-03-18 2016-08-24 中国人民解放军成都军区疾病预防控制中心 Experimental animals retaining frame
CN106725977A (en) * 2016-12-28 2017-05-31 中国人民解放军军事医学科学院放射与辐射医学研究所 Occupational exposure to magnetic fields experiment rat single cage fixing device

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