CN209203604U - Fixation cage tool for batch whole body irradiation mouse - Google Patents

Fixation cage tool for batch whole body irradiation mouse Download PDF

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Publication number
CN209203604U
CN209203604U CN201820602592.8U CN201820602592U CN209203604U CN 209203604 U CN209203604 U CN 209203604U CN 201820602592 U CN201820602592 U CN 201820602592U CN 209203604 U CN209203604 U CN 209203604U
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China
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box body
arc box
whole body
cage tool
irradiation
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CN201820602592.8U
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Chinese (zh)
Inventor
郎海洋
刘军叶
曾丽华
麻秋伟
谢学军
王晋
郭国祯
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Abstract

The utility model relates to whole bodies by irradiated biological effect study field, and in particular to the fixation cage tool for batch whole body irradiation mouse.Including arc box body, multiple ventholes are arranged in arc box body outer wall, and arc tray interior is vertically arranged multiple isolation boards, and cover board is arranged in arc box body top.In the technical program, it not only can guarantee that experimental animal was opposite and move freely, but also the irradiation that animal can be made to receive uniform isodose rate, while having utilized inverse square law, and put according to exposure dose demand in different distance, can reach the purpose of batch whole body various dose irradiation.

Description

Fixation cage tool for batch whole body irradiation mouse
Technical field
The utility model relates to whole bodies by irradiated biological effect study field, and in particular to be used for batch whole body irradiation mouse Fixation cage tool.
Background technique
Animal irradiation experiment is radiation biological effect basis, essential research during teaching and scientific research at different levels Experiment, what experimental animal was most often selected is the toys such as large and small mouse.In irradiation experiment, it is often necessary to by same exposure dose Or same group of other animal is fixed in a certain fixed device, is then irradiated.
But the size and material due to fixed device can all influence the stabilization for the exposure dose that animal finally receives Property, thus, the requirement to animal fixing device is just particularly important, and size has to be suitble to, and should guarantee the work of animal Dynamic degree, and cannot be too large or too small, according to radiated square law of reciprocity, with a batch or one group of same illumination volume requirements Distance of the animal apart from radioactive source must be consistent, as far as possible the guarantee free active position of animal, to reach whole body uniform dose spoke According to.Ensuring to test parameters unanimously can be only achieved experiment effect.
The research achievement of animal irradiation experiment is in Effect Evaluation of the radiation to organism and the system to radiation protection standard Fixed and Radioprotective Effect evaluation has important theory significance and application value.In biological effects of radiation research, radiation Damage and biological effect are closely related with the radioactive dose of research object, but in specific research process, due to impossible Directly taking human as irradiation object, experimental animal or cell can only be used to carry out correlative study for object.
During previous whole animal irradiation experiment, to enable to be received whole body uniform irradiation by according to animal, use The methods of anesthesia, fixed.And various means or fixed material all can have certain shadow to experiment irradiation or absorbed dose Ring, either drug or physical stimulation, organism can all have feedback or stress, have more or less shadow to experimental result Ring, cannot real objective reaction experiment, the desired result of experiment is not achieved.
How to ensure in experimentation, the autonomous free position of animal is the basic guarantee of experiment, batch uniform irradiation, grouping Irradiation, the multiple dosage groupings of once irradiating are that irradiation experiment has to solve the problems, such as.
Summary of the invention
The purpose of this utility model is: the fixation cage tool for being used for batch whole body irradiation mouse is provided, it is above-mentioned existing to overcome There is the defects of technology.
Technical solution used by the utility model is:
It for the fixation cage tool of batch whole body irradiation mouse, is characterized in that including arc box body, outside arc box body Multiple ventholes are arranged in wall, and arc tray interior is vertically arranged multiple isolation boards, and cover board is arranged in arc box body top.
Further, the arc inboard wall of cartridge is provided with inserting groove, and isolation board ends are provided with and the inserting groove phase The plug division of adaptation.
Further, arc box body top is provided with inserting groove, and cover board both ends are provided with mutually fits with the inserting groove The plug division matched.
Further, the inserting groove is in dove-tail form.
Further, arc box body top is provided with limit card slot, and arc box body bottom is provided with and the limit The compatible retention bead of card slot.
Further, arc box body one end is provided with limit card slot, and the other end is provided with and the limit card slot phase The retention bead of adaptation.
Further, the limit card slot is in rectangle.
Further, venthole is provided on the cover board.
Further, the wall thickness of the arc box body is 0.3cm.
Further, the aperture of the venthole is 0.2cm.
The beneficial effects of the utility model are: not only can guarantee that experimental animal was opposite in the technical program and move freely, but also energy So that animal is received the irradiation of uniform isodose rate, while utilizing inverse square law, according to exposure dose demand in different distance It puts, can reach the purpose of batch whole body various dose irradiation.
It solves fixed animal when irradiation animal, and can guarantee the problem of animal is with respect to mobility, on the one hand ensure batch Animal exposure dose uniformity (distance apart from irradiation bomb is identical);On the other hand also ensure that fixed device materials are not influence spoke According to dosage, it may also reach up irradiation animal and ray into relative verticality, can be simultaneously reached once irradiating difference by according to agent Amount completes the demand of batch animal irradiation, which also takes array and lay animal, receives animal not between each other It interference and influences, while to have certain radian to ensure parallel with irradiation bomb for the device.
Detailed description of the invention
Fig. 1 is the main view that embodiment provides;
Fig. 2 is the top view that embodiment provides;
Fig. 3 is the sectional schematic diagram of cover board;
Fig. 4 is the sectional schematic diagram of arc box body;
In figure, 1- arc box body, 2- venthole, 3- isolation board, 4- cover board, 5- inserting groove, the plug division 6-, 7- limiting card Slot, 8- retention bead.
Specific embodiment
Below in conjunction with the attached drawing of the utility model, the technical solution of the utility model is clearly and completely described. Based on the embodiments of the present invention, obtained by those of ordinary skill in the art without making creative efforts Every other embodiment, fall within the protection scope of the utility model.
As Figure 1-Figure 4, the present embodiment provides a kind of fixation cage tools for batch whole body irradiation mouse, including arc Multiple ventholes 2 are arranged in box body 1,1 outer wall of arc box body, and multiple isolation boards 3, arc box body 1 is arranged in 1 inner vertical of arc box body Cover board 4 is arranged in top.
Preferably, 1 inner wall of arc box body is provided with inserting groove 5, and 3 both ends of isolation board are provided with compatible with inserting groove 5 Plug division 6.
Preferably, 1 top of arc box body is provided with inserting groove 5, and 4 both ends of cover board are provided with insert compatible with inserting groove 5 Socket part 6.
Preferably, inserting groove 5 is in dove-tail form.
Preferably, 1 top of arc box body is provided with limit card slot 7, and 1 bottom of arc box body is provided with and 7 phase of limit card slot The retention bead 8 of adaptation.
Preferably, 1 one end of arc box body is provided with limit card slot 7, and the other end is provided with limit compatible with limit card slot 7 Position protrusion 8.
Preferably, limit card slot 7 is in rectangle.
Preferably, venthole 2 is provided on cover board 4.
Preferably, the wall thickness of arc box body 1 is 0.3cm.
Preferably, the aperture of venthole 2 is 0.2cm.
The discharge of flower basket type array according to irradiation devices, that is, radiation source, the single unit system of irradiation bomb similar to a cylindrical body, Animal so is laid around the annular of cylindrical body, can be only achieved uniform full-body exposure.Animal should be fixed relatively, and limitation is dynamic again The mobility of object will also reach whole body irradiation, while not influence the absorption of irradiation dose, should irradiate animal in batches, while again It does not influence each other, that is, maintains the animal on relative separation.Animal is laid around irradiation devices in this way, so that it is uniform to reach batch whole body Dosage irradiates animal, once can satisfy multiple dosage, puts distance difference, and radioactive dose is different.
The present apparatus is made using organic glass, and material is easy to get, easy processing, can be using cambered design in batches Grouping irradiation animal, is separated by isolation board between each other, it is ensured that animal does not influence between each other, before and after device top, low side all Design has venthole, it is ensured that animal is in relatively independent in irradiation process, can be with respect to active position and breathing.
Device the whole body uses the organic glass of 0.3cm thickness to make, and generally 33.5cm*4.5cm*8.5cm is divided into two Point: arc box body and cover board, arc box body are divided into 10 cells, are separated between each cell by stuffiness isolation board, Mei Ge little All there are the venthole of several diameter 0.2cm, arc box body top is opening port, the design of opening port two sides for both ends and front and back under room For inserting groove, inserting groove is closed at one end, and the other end is cover board grafting entrance;Cover board and arc box body match, and cover board is whole all There are the ventholes of diameter 0.2cm.
The present apparatus makes due to using organic glass, transparent, lightly, easy to clean, cheap, and workmanship is simple.Tool Body, one group of cage tool divides 10 mouse positions, is separated, is independent of each other by isolation board between 10 mouse positions, can in batches, one group of cage tool can To be put into 10 mouse, grafting can also be selected as needed with 1-10 mouse, isolation board.Once irradiating can with multiple groups cage tool, According to irradiation demand, various dose is laid using dislocation different distance, and superposition up and down lays animal and increases by one group of more photograph It penetrates.
Such as: 150 mouse need to be divided into 10 groups of irradiations, for dotted or column radioactive source, carry out around surrounding It lays, has calculated the dosage of different distance, with 20 cage tools, one group 15, laid using the superposition of upper and lower 2 cage tools, dislocation differs Away from laying, laid one week around radioactive source, can single fraction irradiation batch, more mouse of various dose.
Above description is only a specific implementation of the present invention, but the protection scope of the utility model is not limited to In this, anyone skilled in the art within the technical scope disclosed by the utility model, can readily occur in variation Or replacement, it should be covered within the scope of the utility model.Therefore, the protection scope of the utility model should be with the power Subject to the protection scope that benefit requires.

Claims (8)

1. being used for the fixation cage tool of batch whole body irradiation mouse, it is characterised in that: including arc box body, the setting of arc box body outer wall Multiple ventholes, arc tray interior are vertically arranged multiple isolation boards, and cover board is arranged in arc box body top;
Arc box body top is provided with limit card slot, and arc box body bottom is provided with limit compatible with the limit card slot Position protrusion;
Arc box body one end is provided with limit card slot, and the other end is provided with limit convex compatible with the limit card slot It rises.
2. the fixation cage tool according to claim 1 for batch whole body irradiation mouse, it is characterised in that: the arc box Internal wall is provided with inserting groove, and isolation board ends are provided with plug division compatible with the inserting groove.
3. the fixation cage tool according to claim 1 for batch whole body irradiation mouse, it is characterised in that: the arc box Body top is provided with inserting groove, and cover board both ends are provided with plug division compatible with the inserting groove.
4. the fixation cage tool according to claim 2 or 3 for batch whole body irradiation mouse, it is characterised in that: described to insert Access slot is in dove-tail form.
5. the fixation cage tool according to claim 1 for batch whole body irradiation mouse, it is characterised in that: the limiting card Slot is in rectangle.
6. the fixation cage tool according to claim 1 for batch whole body irradiation mouse, it is characterised in that: on the cover board It is provided with venthole.
7. the fixation cage tool according to claim 1 for batch whole body irradiation mouse, it is characterised in that: the arc box The wall thickness of body is 0.3cm.
8. the fixation cage tool according to claim 1 for batch whole body irradiation mouse, it is characterised in that: the venthole Aperture be 0.2cm.
CN201820602592.8U 2018-04-25 2018-04-25 Fixation cage tool for batch whole body irradiation mouse Active CN209203604U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820602592.8U CN209203604U (en) 2018-04-25 2018-04-25 Fixation cage tool for batch whole body irradiation mouse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820602592.8U CN209203604U (en) 2018-04-25 2018-04-25 Fixation cage tool for batch whole body irradiation mouse

Publications (1)

Publication Number Publication Date
CN209203604U true CN209203604U (en) 2019-08-06

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Country Status (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111558406A (en) * 2020-04-28 2020-08-21 中国人民解放军海军军医大学 Remote control type large-batch sample point source irradiation rack and irradiation laboratory
CN112674901A (en) * 2020-12-18 2021-04-20 中国辐射防护研究院 Tool and method for batch radioactive skin injury experiment of animals

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111558406A (en) * 2020-04-28 2020-08-21 中国人民解放军海军军医大学 Remote control type large-batch sample point source irradiation rack and irradiation laboratory
CN112674901A (en) * 2020-12-18 2021-04-20 中国辐射防护研究院 Tool and method for batch radioactive skin injury experiment of animals

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