CN110063925A - A kind of acne-removing composition and preparation method thereof - Google Patents
A kind of acne-removing composition and preparation method thereof Download PDFInfo
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- CN110063925A CN110063925A CN201910206893.8A CN201910206893A CN110063925A CN 110063925 A CN110063925 A CN 110063925A CN 201910206893 A CN201910206893 A CN 201910206893A CN 110063925 A CN110063925 A CN 110063925A
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Abstract
The present invention provides a kind of acne-removing composition and preparation method thereof, acne-removing composition by weight percentage, including 5-100 parts of ethyl alcohol, 5-100 parts of glycerol, 0.05-70 parts of naringenin, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, 0.05-50 parts of rheum emodin, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, 0.05-50 parts of American-cockroach-extract, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate.Acne-removing composition provided by the invention and preparation method thereof has preferable fungistatic effect.
Description
Technical field
The invention belongs to beauty and cosmetic field field, and in particular to a kind of acne-removing composition and preparation method thereof.
Background technique
Acne (being commonly called as acne, whelk) is a kind of chronic skin disease of sebaceous glands, its generation mainly divides with sebum
It is closely related to secrete the factors such as excessive, pilosebaceous duct blocking, bacterium infection and inflammatory reaction, adolesces in descendant's body
Androgen levels increase, and generate a large amount of sebums.Catheter blockage simultaneously, dyssebacia form horn plug, that is, micro mist thorn.Hair follicle
Middle multiple-microorganism especially propionibacterium acnes mass propagation, while chemotactic inflammatory cell and medium, finally induce and aggravate
Inflammatory reaction.
Although the definite cause of disease and pathogenesis of current acne are still not very clear, microorganism is considered as what it was fallen ill
One of Important cause of disease.Propionibacterium acnes predominantly induce inflammation as generally acknowledged most important pathogenic microorganisms, pathogenic mechanism
Reaction, promote hair follicle sebum galandular epithelium angling and promote smegma etc..In addition, staphylococcus aureus, Escherichia coli,
Surface staphylococcus, Pseudomonas aeruginosa etc. are worked in pathogenesis of acne, can be with propionibacterium acnes common pathogenetic.
Commonly using anti-acne drug for the treatment of whelk at present includes antiandrogen drug, antibiotic, Tretinoin, peroxide
Change benzoyl etc..But these current therapeutic scheme effects are not ideal enough, cause whelk flickering, repeated, it is difficult to root
It removes.Therefore, it is necessary to a kind of new technical solutions to solve the above technical problems.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of preferable acne-removing composition of fungistatic effect and its preparation side
Method.
The present invention provides a kind of acne-removing composition, by weight percentage, including 5-100 parts of ethyl alcohol, 5-100 parts of glycerol,
0.05-70 parts of naringenin, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, rheum emodin
0.05-50 parts, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, American-cockroach-extract
0.05-50 parts, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate.
Preferably, described ethyl alcohol 10-80 parts, 10-80 parts of glycerol, 0.5-50 parts of naringenin, 0.5-30 parts of chlorogenic acid, You Jia
Sharp essential oil 0.5-30 parts, 0.5-30 parts of eugenol, 0.05-20 parts of rheum emodin, 0.05-20 parts of menthyl lactate, tea polyphenols 0.05-
20 parts, 0.05-20 parts of Quercetin, 0.05-20 parts of American-cockroach-extract, 0.05-20 parts of allantoin and vitamine A acetate
0.05-20 parts.
Preferably, described ethyl alcohol 20-70 parts, 20-70 parts of glycerol, 1-20 parts of naringenin, 1-10 parts of chlorogenic acid, You Jiali essence
1-10 parts oily, 1-10 parts of eugenol, 0.1-10 parts of rheum emodin, 0.1-10 parts of menthyl lactate, 0.1-10 parts of tea polyphenols, the Mongolian oak
0.1-10 parts of skin element, 0.1-10 parts of American-cockroach-extract, 0.1-10 parts of allantoin and 0.1-10 parts of vitamine A acetate.
Preferably, described ethyl alcohol 30-50 parts, 30-50 parts of glycerol.
Preferably, described naringenin 2-6 parts, 2-8 parts of chlorogenic acid, 1-6 parts of eucalyptus quintessence oil, 1-6 parts of eugenol.
Preferably, described vitamine A acetate 0.1-3 parts, 0.1-1 parts of menthyl lactate, 0.1-1 parts of allantoin, tea it is more
0.1-2 parts of phenol, 0.1-2 parts of Quercetin, 0.1-2 parts of American-cockroach-extract.
The present invention also provides a kind of acne-removing compositions, by weight percentage, by 5-100 parts of ethyl alcohol, 5-100 parts of glycerol,
0.05-70 parts of naringenin, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, rheum emodin
0.05-50 parts, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, American-cockroach-extract
0.05-50 parts, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate compositions.
Preferably, described ethyl alcohol 20-70 parts, 20-70 parts of glycerol, 1-20 parts of naringenin, 1-10 parts of chlorogenic acid, You Jiali essence
1-10 parts oily, 1-10 parts of eugenol, 0.1-10 parts of rheum emodin, 0.1-10 parts of menthyl lactate, 0.1-10 parts of tea polyphenols, Quercetin
0.1-10 parts, 0.1-10 parts of American-cockroach-extract, 0.1-10 parts of allantoin and 0.1-10 parts of vitamine A acetate
The present invention also provides a kind of preparation methods of acne-removing composition, include the following steps:
(1) rheum emodin, naringenin, chlorogenic acid, vitamine A acetate, ethyl alcohol, glycerol are stirred be heated to 25 DEG C-
50℃；
(2) eugenol, eucalyptus quintessence oil, menthyl lactate mixing is added；
(3) when temperature is 20 DEG C -30 DEG C, allantoin, tea polyphenols, Quercetin, American-cockroach-extract is added, stirs
To acne-removing composition；
Preferably, the temperature in the step (1) is 25 DEG C -30 DEG C.
Acne-removing composition provided by the invention and preparation method thereof has preferable fungistatic effect.
Detailed description of the invention
It is more particularly described by the preferred embodiment of the present invention shown in the drawings, the above and other purpose of the present invention, feature
It will be become more fully apparent with advantage.Identical appended drawing reference indicates identical part in all the attached drawings, and not deliberately by real
Size equal proportion scaling in border draws attached drawing, it is preferred that emphasis is shows this purport.
Fig. 1 is inhibition zone method antibacterial measurement experiment feminine gender group Escherichia coli inhibitory effect figure；
Fig. 2 is inhibition zone method antibacterial measurement experiment feminine gender group staphylococcus aureus inhibitory effect figure；
Fig. 3 is inhibition zone method antibacterial measurement experiment feminine gender group pseudomonas aeruginosa inhibitory effect figure；
Fig. 4 is inhibition zone method antibacterial measurement experiment feminine gender group propionibacterium acnes inhibitory effect figure；
Fig. 5 is inhibition zone method antibacterial measurement experiment Chinese medicine anti-acne lotion group Escherichia coli inhibitory effect figure；
Fig. 6 is inhibition zone method antibacterial measurement experiment Chinese medicine anti-acne lotion group staphylococcus aureus inhibitory effect figure；
Fig. 7 is inhibition zone method antibacterial measurement experiment Chinese medicine anti-acne lotion group pseudomonas aeruginosa inhibitory effect figure；
Fig. 8 is inhibition zone method antibacterial measurement experiment Chinese medicine anti-acne lotion group propionibacterium acnes inhibitory effect figure；
Fig. 9 is the effect picture of turbidimetry antibacterial measurement experiment feminine gender group and Chinese medicine anti-acne 2 hours of lotion group Spawn incubation；
Figure 10 is the effect of turbidimetry antibacterial measurement experiment feminine gender group and Chinese medicine anti-acne 12 hours of lotion group Spawn incubation
Figure.
Specific embodiment
Technical solution of the present invention is described in further detail combined with specific embodiments below, so that the technology of this field
Personnel can better understand the present invention and can be practiced, but illustrated embodiment is not as a limitation of the invention.
The embodiment of the present invention provides a kind of acne-removing composition, by weight percentage, including 5-100 parts of ethyl alcohol, glycerol 5-
100 parts, it is 0.05-70 parts of naringenin, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, big
0.05-50 parts of flavine, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, American cockroach mention
Take 0.05-50 parts of object, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate.
Acne-removing composition provided by the present invention has the effect that the present invention is used according to the thought of Chinese medicine monarch
Medicine.Rheum emodin is monarch drug in a prescription, has the function of sterilization, antibacterial, can go deep into hair follicle depths, eliminate skin oil and fat and dirt, kill Cuo
Sore Propionibacterium flora related to other acnes；Aurantiin in naringenin can enhance fungicidal effectiveness；Chlorogenic acid and vitamin A vinegar
Acid esters is ministerial drug, and monarch drug in a prescription ingredient is promoted to penetrate cuticula, itself is also through cuticula, the effect of enhancing infiltration sterilization, control office
Portion's infection.Eucalyptus quintessence oil and eugenol are adjuvant, can assisted sterilization anti-inflammatory, also can be used as natural anticorrosion ingredient.Lactic acid is thin
The addition of lotus ester assigns product refrigerant sense, can improve using feeling, uncomfortable caused by reducing because of acne.Tea polyphenols and Quercetin
Addition, have anti-oxidant, remove the effect of free radical, restrain pore, delay senescence.Allantoin and American-cockroach-extract plus
Enter, its role is to the tissue repair effects of further concertedness enhancing acne-removing composition, promote cell growth, cell new old generation
It thanks, cutin-softening layer albumen, accelerates wound-healing abilities.
Acne-removing composition of the present invention can make an addition in skin care item, can be made into the cosmetics such as face cream, anti-acne creams, facial cleanser.
Anti-acne lotion additive amount in cosmetic product is 0.5-10%.
Rheum emodin, anthraquinone derivatives are the main effective monomers of Chinese herb rhubarb, are practically insoluble in water, be dissolved in ethyl alcohol and
Aqueous slkali.There is stronger inhibiting effect to clinical common Anaerobic Bacteria, inhibits the final result of nucleic acid and protein synthesis, make
Bacterial growth is suppressed, and is the inhibitor of arachidonic acid lipoxygenase, can effectively reduce the inflammatory reaction of acne, to reduce
Skin lesion scar of acne etc..
Naringenin is the glucoside member of naringin, belongs to flavanone kind composition, have antibacterial, it is anti-inflammatory, remove free radical, be anti-
The effect of oxidation.There is stronger antibacterial action to propionibacterium acnes, staphylococcus aureus.It is sent out simultaneously by experiment in vitro
Existing, shaddock ped is known as antiphlogistic effects, increases with dosage, antiphlogistic effects enhancing.
Chlorogenic acid is one of the main antibacterial of honeysuckle, antiviral effective pharmaceutical component.With antibacterial, antiviral, removing
The effects of free radical.To effectively removing, interior free yl, the normal structure and function of maintenance body cell, anti-aging etc. are existing
Elephant plays a significant role.
Vitamine A acetate, the vitamin be it is fat-soluble, be adjust Epithelial cell growth with health it is necessary because
Son keeps coarse aging skin surface thinning, promotes cell metabolism normalization, keeps skin flexible, soft and moist skin.
Eucalyptus quintessence oil, is the essential oil that extraction is refined using You Jiali tree, this essential oil has the function of antibacterial anti-inflammatory, can promote
Into neoblast tissue construction, pre- anti-acne small pox growth.Wound, ulcer and inflammation situation are reacted using after eucalyptus quintessence oil
Well.
Eugenol is colourless or pale yellow liquid, there is strong cloves fragrance, not soluble in water.It is mainly used for antibacterial, to gold
Staphylococcus aureus and Escherichia coli etc. have inhibiting effect.
Menthyl lactate, be it is a kind of be identified as it is fabulous, without adverse reaction such as burning sensation, excitement and tingling sensation
Colorless and odorless freshener.It is easy that extraordinary cooling effect is had by percutaneous absorption, while playing the work of supplement transepidermal water
With.
Tea polyphenols are all natural antioxidant foods extracted from tealeaves, have oxidation resistance strong, have no toxic side effect
Feature.Tea polyphenols play the role of removing free radical, can inhibit lipoxygenase and lipid peroxidation in skin mitochondria, thus
With anti-aging effect.
Quercetin removes DPPH free radical, hydroxyl radical free radical, superoxide radical, has stronger oxidation resistance, slow down skin
Skin aging；There is certain inhibiting effect to Escherichia coli and staphylococcus aureus, can be used as the natural anticorrosion ingredient of cosmetics.
Allantoin can form double salt in conjunction with many kinds of substance, have sterilization and anticorrosion, analgesic, antioxidation, skin can be made to protect
Water holding part moistens and soft, is the additive of cosmetics, can promote tissue growth, cell metabolism, cutin-softening layer
Albumen.
American-cockroach-extract, accelerate necrotic tissue fall off, repair wound and wound surface rapidly, can effectively antagonism free radical to machine
The damage of body, while also there is anti-inflammatory and analgesic effect.
In a preferred embodiment, ethyl alcohol 10-80 parts, 10-80 parts of glycerol, 0.5-50 parts of naringenin, 0.5-30 parts of chlorogenic acid,
0.5-30 parts of eucalyptus quintessence oil, 0.5-30 parts of eugenol, 0.05-20 parts of rheum emodin, 0.05-20 parts of menthyl lactate, tea polyphenols
0.05-20 parts, 0.05-20 parts of Quercetin, 0.05-20 parts of American-cockroach-extract, 0.05-20 parts of allantoin and vitamin A vinegar
0.05-20 parts of acid esters.
In a preferred embodiment, ethyl alcohol 20-70 parts, 20-70 parts of glycerol, 1-20 parts of naringenin, 1-10 parts of chlorogenic acid, You Jia
Sharp essential oil 1-10 parts, 1-10 parts of eugenol, 0.1-10 parts of rheum emodin, 0.1-10 parts of menthyl lactate, 0.1-10 parts of tea polyphenols, Mongolian oak
0.1-10 parts of skin element, 0.1-10 parts of American-cockroach-extract, 0.1-10 parts of allantoin and 0.1-10 parts of vitamine A acetate.
In a preferred embodiment, ethyl alcohol 30-50 parts, 30-50 parts of glycerol.
In a preferred embodiment, naringenin 2-6 parts, 2-8 parts of chlorogenic acid, 1-6 parts of eucalyptus quintessence oil, 1-6 parts of eugenol.
In a preferred embodiment, vitamine A acetate 0.1-3 parts, 0.1-1 parts of menthyl lactate, 0.1-1 parts of allantoin,
0.1-2 parts of tea polyphenols, 0.1-2 parts of Quercetin, 0.1-2 parts of American-cockroach-extract.
The present invention also provides a kind of acne-removing compositions of embodiment, by weight percentage, by 5-100 parts of ethyl alcohol, glycerol 5-
100 parts, it is 0.05-70 parts of naringenin, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, big
0.05-50 parts of flavine, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, American cockroach mention
Take 0.05-50 parts of object, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate compositions.
In a preferred embodiment, ethyl alcohol 20-70 parts, 20-70 parts of glycerol, 1-20 parts of naringenin, 1-10 parts of chlorogenic acid, You Jia
Sharp essential oil 1-10 parts, 1-10 parts of eugenol, 0.1-10 parts of rheum emodin, 0.1-10 parts of menthyl lactate, 0.1-10 parts of tea polyphenols, Mongolian oak
0.1-10 parts of skin element, 0.1-10 parts of American-cockroach-extract, 0.1-10 parts of allantoin and 0.1-10 parts of vitamine A acetate
The embodiment of the present invention also provides a kind of preparation method of acne-removing composition, includes the following steps:
(1) rheum emodin, naringenin, chlorogenic acid, vitamine A acetate, ethyl alcohol, glycerol are stirred be heated to 25 DEG C-
50℃；
(2) eugenol, eucalyptus quintessence oil, menthyl lactate mixing is added；
(3) when temperature is 20 DEG C -30 DEG C, allantoin, tea polyphenols, Quercetin, American-cockroach-extract is added, stirs
To acne-removing composition；
In a preferred embodiment, the temperature in step (1) is 25 DEG C -30 DEG C.
In order to have further understanding and understanding to technical solution of the present invention, several preferred embodiments pair are now enumerated
It is described in further details.The formula of each embodiment and comparative example, by weight, as shown in table 1.
Table 1
Anti-acne lotion is prepared following preparation method by using according to the formula in table 1:
(1) quantitative rheum emodin, naringenin, chlorogenic acid, vitamine A acetate, ethyl alcohol, glycerol are added agitated kettle and carried out
Stirring dissolves it sufficiently, is heated to 25 DEG C -30 DEG C；
(2) eugenol, eucalyptus quintessence oil, the stirring of menthyl lactate premixed liquid is added；
(3) slightly cold, allantoin, tea polyphenols, Quercetin, American cockroach is added, stirs evenly；
(4) it obtains freely dispersing, homogeneous and transparent liquid.
Effect example
The anti-acne lotion that above-described embodiment 1 is prepared carries out inhibition zone method antibacterial measurement experiment.
Strains tested: Escherichia coli (E.coli, ATCC 52922), staphylococcus aureus (S.aureus, ATCC
25923), pseudomonas aeruginosa (P.Aeruginosa, ATCC 27853), propionibacterium acnes (P.acnes, ATCC 6919)
Strain is both from aging institute, Guangdong medical university.
LB culture medium: 5.0 grams of sodium chloride are taken, 10.0 grams of peptone, 4.0 grams of yeast extract, 15.0 grams of agar, is added
In 1000 ml deionized waters, stirring to each ingredient is completed to dissolve, and dilute sodium hydroxide is added and adjusts the pH value of culture medium to 7.0,
High-temperature sterilization 30 minutes at 121 DEG C, for use.
Experimental group: experiment is divided into the Chinese medicine anti-acne lotion group of negative group (deionized water group) and embodiment 1.
Strain (1.0 × 107CFU/mL): being first uniformly applied to containing LB culture medium by experimental procedure and diameter is 9 centimetres
Culture dish in, and the anti-acne lotion for taking 100 milligrams of Examples 1 to 3 any described is placed in filter paper enzyme or Odontothrips loti
Culture dish center.Bacterium culture dish will be contained to be placed in incubator, 37 DEG C are cultivated 24 hours, and inhibition zone size is observed.
Experimental result: as shown in Figures 1 to 4, negative group (deionized water group) without any antibacterial effect；Such as Fig. 5 to Fig. 8 institute
Show, the anti-acne lotion group of the present embodiment 1 is to Escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, propionibacterium acnes tool
There is obvious antibacterial effect, shows that the anti-acne lotion group of the application preparation has stronger inhibiting effect, bactericidal effect is obvious.
The anti-acne lotion that above-described embodiment 1 is prepared carries out turbidimetry antibacterial measurement experiment.
The preparation of strains tested and LB culture medium is same as above.
Experimental group: experiment is divided into negative group (deionized water group), the Chinese medicine anti-acne lotion group of embodiment 1.
Experimental procedure: strain (1.0 × 107CFU/mL) is added in 2.0 milliliters of LB liquid, and 50.0 milligrams of embodiments are added
1~3 Chinese medicine anti-acne lotion, 37 DEG C after culture 24 hours in incubator, using microplate reader (600nm at) measurement
OD value.
Experimental result: as shown in Figure 9 and Figure 10, negative group (deionized water group) without any bacteriostasis property；Chinese medicine anti-acne
Liquid group has certain inhibitory effect to the growth of propionibacterium acnes；Growth of the Chinese medicine anti-acne lotion group to propionibacterium acnes
Inhibitory effect it is obvious, show the application preparation Chinese medicine anti-acne lotion group have stronger inhibition Escherichia coli, golden yellow Portugal
Grape coccus, pseudomonas aeruginosa, the effect of propionibacterium acnes.
In conjunction with above-mentioned two experiment, illustrate the formula of the embodiment of the present application to Escherichia coli, staphylococcus aureus, verdigris
Pseudomonad, propionibacterium acnes have stronger inhibiting effect, can play preferable anti-acne effect.
The above description is only a preferred embodiment of the present invention, is not intended to limit the scope of the invention, all utilizations
Equivalent structure or equivalent flow shift made by present specification is applied directly or indirectly in other relevant technologies
Field is included within the scope of the present invention.
Claims (10)
1. a kind of acne-removing composition, which is characterized in that by weight percentage, including 5-100 parts of ethyl alcohol, 5-100 parts of glycerol, shaddock
0.05-70 parts of skin element, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, rheum emodin 0.05-
50 parts, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, American-cockroach-extract 0.05-
50 parts, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate.
2. acne-removing composition as described in claim 1, which is characterized in that described ethyl alcohol 10-80 parts, 10-80 parts of glycerol, shaddock ped
0.5-50 parts plain, 0.5-30 parts of chlorogenic acid, 0.5-30 parts of eucalyptus quintessence oil, 0.5-30 parts of eugenol, 0.05-20 parts of rheum emodin,
0.05-20 parts of menthyl lactate, 0.05-20 parts of tea polyphenols, 0.05-20 parts of Quercetin, 0.05-20 parts of American-cockroach-extract,
0.05-20 parts and vitamine A acetate 0.05-20 parts of allantoin.
3. acne-removing composition as described in claim 1, which is characterized in that described ethyl alcohol 20-70 parts, 20-70 parts of glycerol, shaddock ped
1-20 parts plain, 1-10 parts of chlorogenic acid, 1-10 parts of eucalyptus quintessence oil, 1-10 parts of eugenol, 0.1-10 parts of rheum emodin, menthyl lactate
0.1-10 parts, 0.1-10 parts of tea polyphenols, Quercetin 0.1-10 parts described, 0.1-10 parts of American-cockroach-extract, allantoin 0.1-
10 parts and vitamine A acetate 0.1-10 parts.
4. acne-removing composition as described in claim 1, which is characterized in that described ethyl alcohol 30-50 parts, 30-50 parts of glycerol.
5. acne-removing composition as described in claim 1, which is characterized in that described naringenin 2-6 parts, 2-8 parts of chlorogenic acid, You Jia
Sharp essential oil 1-6 parts, 1-6 parts of eugenol.
6. acne-removing composition as described in claim 1, which is characterized in that described vitamine A acetate 0.1-3 parts, lactic acid it is thin
0.1-1 parts of lotus ester, 0.1-1 parts of allantoin, 0.1-2 parts of tea polyphenols, 0.1-2 parts of Quercetin, 0.1-2 parts of American-cockroach-extract.
7. a kind of acne-removing composition, which is characterized in that by weight percentage, by 5-100 parts of ethyl alcohol, 5-100 parts of glycerol, shaddock ped
0.05-70 parts plain, 0.05-50 parts of chlorogenic acid, 0.05-50 parts of eucalyptus quintessence oil, 0.05-50 parts of eugenol, rheum emodin 0.05-50
Part, 0.05-50 parts of menthyl lactate, 0.05-50 parts of tea polyphenols, 0.05-50 parts of Quercetin, American-cockroach-extract 0.05-50
Part, 0.05-50 parts of allantoin and 0.05-50 parts of vitamine A acetate compositions.
8. acne-removing composition as claimed in claim 7, which is characterized in that described ethyl alcohol 20-70 parts, 20-70 parts of glycerol, shaddock ped
1-20 parts plain, 1-10 parts of chlorogenic acid, 1-10 parts of eucalyptus quintessence oil, 1-10 parts of eugenol, 0.1-10 parts of rheum emodin, menthyl lactate
0.1-10 parts, 0.1-10 parts of tea polyphenols, 0.1-10 parts of Quercetin, 0.1-10 parts of American-cockroach-extract, 0.1-10 parts of allantoin
With 0.1-10 parts of vitamine A acetate.
9. a kind of preparation method of acne-removing composition as claimed in any one of claims 1 to 6, which is characterized in that including walking as follows
It is rapid:
(1) rheum emodin, naringenin, chlorogenic acid, vitamine A acetate, ethyl alcohol, glycerol are stirred and are heated to 25 DEG C -50 DEG C；
(2) eugenol, eucalyptus quintessence oil, menthyl lactate mixing is added；
(3) when temperature is 20 DEG C -30 DEG C, allantoin, tea polyphenols, Quercetin, American-cockroach-extract is added, stirs to get and dispels
Acne composition.
10. preparation method as claimed in claim 9, which is characterized in that the temperature in the step (1) is 25 DEG C -30 DEG C.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115607638A (en) * | 2022-12-02 | 2023-01-17 | 吉林华康药业股份有限公司 | Traditional Chinese medicine composition for infantile indigestion with food retention and preparation method thereof |
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