CN104739686A - Anti-acne cream and preparation method thereof - Google Patents

Anti-acne cream and preparation method thereof Download PDF

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Publication number
CN104739686A
CN104739686A CN201310735163.XA CN201310735163A CN104739686A CN 104739686 A CN104739686 A CN 104739686A CN 201310735163 A CN201310735163 A CN 201310735163A CN 104739686 A CN104739686 A CN 104739686A
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temperature
oil
pot
extract
minutes
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CN201310735163.XA
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Chinese (zh)
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陈冬英
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DALIAN MEILE BIOLOGICAL TECHNOLOGY DEVELOPMENT Co Ltd
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DALIAN MEILE BIOLOGICAL TECHNOLOGY DEVELOPMENT Co Ltd
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Priority to CN201310735163.XA priority Critical patent/CN104739686A/en
Publication of CN104739686A publication Critical patent/CN104739686A/en
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Abstract

An anti-acne cream mainly comprises avocado oil, squalane, caprylic/capric glyceride, dimethicone, EMT-10 and deionized water A. A preparation method of the anti-acne cream comprises the following steps: 1, adding avocado oil, squalane, caprylic/capric glyceride, dimethicone, EMT-10, Olivem1000, apricot kernel oil, bisabolol and vitamin E acetate into an oil pot; 2, mixing glycerin with xanthan gum; 3, adding deionized water A into a water pot, adding a mixture obtained in step 2, and adding seamollient, allantoin and triclosan into the water pot; 4, heating an emulsifying pot; 5, mixing arbutin with deionized water B; 6, mixing 1,3-propylene glycol, a small cucumber extract product, a witch hazel extract product, a Salvia miltiorrhiza extract product, a little chrysanthemum extract product and a wheat germ extract product; 7, pumping the material in the oil pot into the emulsifying pot; 8, pumping the material in the water pot into the emulsifying pot; 9, cooling; 10, adding Coleus Barbatus oil, a mixture obtained in step 5 and a mixture obtained in step 6 into the emulsifying pot, adding methylisothiazolinone and an essence, and stirring; 11, sampling; 12, discharging; and 13, packaging. The anti-acne cream improves the anti-inflammation and skin endurance ability, and can remove acne marks.

Description

A kind of acne eliminating cream and preparation method thereof
Technical field
The present invention relates to technical field of skin care, particularly a kind of acne eliminating cream and preparation method thereof.
Background technology
Acne is chronic inflammation hair follicle sebum gland disease, is one of modal disease of department of dermatologry, and its morbidity is main and sex hormone level, sebaceous gland are secreted in a large number, propionibacterium acnes is bred, and the factors such as the dyskeratosis of pilosebaceous duct and inflammation are correlated with.Although acne is the disease having spontaneous recovery to be inclined to, the cicatrix that acne itself and acne treatment cause not in time, the quality of life of patient can be had a strong impact on, cause stress and the financial burden of patient, need concern be caused.Acne is apt to occur in buccal, forehead, buccal and nasolabial fold, is secondly chest, back and shoulder.Local external use's treatment is based on degrease, dissolving cutin, antiinflammatory sterilization.Its weak point: can not work in coordination with and improve the antibacterial moisture-keeping function of antiinflammatory, the tolerance of skin can not be improved, can not, while whitening, go trace acne removing to print.
Summary of the invention
The object of this invention is to provide the antibacterial moisture-keeping function of a kind of collaborative raising antiinflammatory, improve the tolerance of skin, while whitening, a kind of acne eliminating cream going trace acne removing to print and preparation method thereof.
Technical scheme of the present invention is: a kind of acne eliminating cream, its composition mainly comprises American Avocado Tree oil, squalane, Miglyol 812, dimethicone, EMT-10, Olivem 1000, almond oil, bisabolol, Vitamin E acetate, glycerol, xanthan gum, Sargassum spirit, allantoin, deionized water A, triclosan, sheath stamen oil, arbutin, deionized water B, 1,3-PD, Gherkin extract, hamamelis extract, Radix Salviae Miltiorrhizae extract, little Flos Chrysanthemi extract, wheat malt germ extract, Methylisothiazolinone and essence.Wherein, be 1 ultimate unit with deionized water A, deionized water A and American Avocado Tree oil, squalane, Miglyol 812, dimethicone, EMT-10, Olivem 1000, almond oil, bisabolol, Vitamin E acetate, glycerol, xanthan gum, Sargassum spirit, allantoin, triclosan, sheath stamen oil, arbutin, deionized water B, 1,3-PD, Gherkin extract, hamamelis extract, Radix Salviae Miltiorrhizae extract, little Flos Chrysanthemi extract, wheat malt germ extract, the mass ratio of Methylisothiazolinone and essence is 1:0.02178 ~ 0.02662, 1:0.01449 ~ 0.01771,1:0.04356 ~ 0.05324,1:0.02178 ~ 0.02662,1:0.02178 ~ 0.02662,1:0.01449 ~ 0.01771,1:0.02907 ~ 0.03553,1:0.00288 ~ 0.00352,1:0.00288 ~ 0.00352,1:0.06013 ~ 0.10127,1:0.00216 ~ 0.00264,1:0.02551 ~ 0.03909,1:0.00432 ~ 0.00528,1:0.00144 ~ 0.00176,1:0.01449 ~ 0.01771,1:0.04356 ~ 0.05324,1:0.04356 ~ 0.05324,1:0.06013 ~ 0.10127,1:0.00873 ~ 0.01067,1:0.01161 ~ 0.01419,1:0.00729 ~ 0.00891,1:0.00729 ~ 0.00891,1:0.04814 ~ 0.08106,1:0.00288 ~ 0.00352,1:0.00045 ~ 0.00055.
The manufacture method of acne eliminating cream realizes according to the following steps:
(1) American Avocado Tree oil, squalane, Miglyol 812, dimethicone, EMT-10, Olivem 1000, almond oil, bisabolol, Vitamin E acetate are put into oil cauldron and are mixed, heating-up temperature 80 DEG C ± 2 DEG C, constant temperature stirs 10 minutes, and stirring and dissolving is even, stand-by;
(2) glycerol and xanthan gum mixing, stir, stand-by;
(3) add in kettle by deionized water A, open stirring, added by the material in step 2, stir, start heating, then add in kettle by Sargassum spirit, allantoin, triclosan, temperature controls at 85 DEG C ± 2 DEG C, stand-by;
(4) heating emulsification pot, about temperature 45 C, evacuation, vacuum remains on 0.05Mpa.
(5) arbutin, deionized water B mix, and temperature is no more than 45 DEG C, and stirring and dissolving is even.Stand-by;
(6) 1,3-PD, Gherkin extract, hamamelis extract, Radix Salviae Miltiorrhizae extract, little Flos Chrysanthemi extract, wheat malt germ extract mixing, temperature is no more than 45 DEG C, and stirring and dissolving is even, stand-by;
(7) will meet the requirements of in oil cauldron material suction emulsifying pot, open stirring, mixing speed 300rpm, temperature 80 DEG C ± 1 DEG C;
(8) rapidly by kettle material suction emulsifying pot, mixing speed brings up to 500rpm, opens homogenizer, homogenizing speed 1800rpm, treats that material all exhausts, and homogenizing speed brings up to 2000rpm, homogenizing time 6 minutes.Homogenizing terminates, and constant temperature stirs 10 minutes;
(9) lower the temperature, open the cooling water of emulsifying pot, cooling rate 3 DEG C/2 minutes, treats that temperature reduces to 70 DEG C, again opens homogenizer, homogenizing speed 1800rpm, homogenizing time 3 minutes;
(10) treat that temperature reduces to 60 DEG C, add sheath stamen oil, mixing speed reduces to 400rpm; Temperature reduces to 45 DEG C, all adds in emulsifying pot by step 5 and step 6 material, stirs 5 minutes; Add Methylisothiazolinone to continue mutually to stir with essence;
(11) sample, analyze; Do discharging to prepare, sterilization discharge tank, opens uviol lamp, irradiates 10 minutes simultaneously;
(12) treat that temperature reduces to 40 DEG C, after sample analysis result is qualified, discharging;
(13) material taken the dish out of the pot pushes rest chamber, ageing fill afterwards in 12 hours, packaging.
The present invention compared with prior art tool has the following advantages: the antibacterial moisture-keeping function of collaborative raising antiinflammatory, improves the tolerance of skin, while whitening, goes trace acne removing to print.
detailed description of the invention
Embodiment 1
The manufacture method of acne eliminating cream realizes according to the following steps:
(1) American Avocado Tree oil 0.02178kg, squalane 0.01449 kg, Miglyol 812 0.04356 kg, dimethicone 0.02178 kg, EMT-100.02178 kg, Olivem 10000.01449 kg, almond oil 0.02907 kg, bisabolol 0.00288 kg, Vitamin E acetate 0.00288 kg put into oil cauldron and mix, heating-up temperature 80 DEG C ± 2 DEG C, constant temperature stirs 10 minutes, stirring and dissolving is even, stand-by;
(2) glycerol 0.06013 kg and xanthan gum 0.00216 kg mixes, and stirs, stand-by;
(3) deionized water A1.1 kg is added in kettle, open stirring, the material in step 2 is added, stir, start heating, then Sargassum spirit 0.02551 kg, allantoin 0.00432 kg, triclosan 0.00144 kg are added in kettle, temperature controls at 85 DEG C ± 2 DEG C, stand-by;
(4) heating emulsification pot, about temperature 45 C, evacuation, vacuum remains on 0.05Mpa;
(5) arbutin 0.04356 kg, deionized water B0.04356 kg mix, and temperature is no more than 45 DEG C, and stirring and dissolving is even, stand-by;
(6) 1, ammediol 0.06013 kg, Gherkin extract 0.00873 kg, hamamelis extract 0.01161 kg, Radix Salviae Miltiorrhizae extract 0.00729 kg, little Flos Chrysanthemi extract 0.00729 kg, wheat malt germ extract mix 0.04814 kg, temperature is no more than 45 DEG C, stirring and dissolving is even, stand-by;
(7) will meet the requirements of in oil cauldron material suction emulsifying pot, open stirring, mixing speed 300rpm, temperature 80 DEG C ± 1 DEG C;
(8) rapidly by kettle material suction emulsifying pot, mixing speed brings up to 500rpm, opens homogenizer, homogenizing speed 1800rpm, treats that material all exhausts, and homogenizing speed brings up to 2000rpm, homogenizing time 6 minutes.Homogenizing terminates, and constant temperature stirs 10 minutes;
(9) lower the temperature, open the cooling water of emulsifying pot, cooling rate 3 DEG C/2 minutes, treats that temperature reduces to 70 DEG C, again opens homogenizer, homogenizing speed 1800rpm, homogenizing time 3 minutes;
(10) treat that temperature reduces to 60 DEG C, add sheath stamen oil 0.01449 kg, mixing speed reduces to 400rpm; Temperature reduces to 45 DEG C, all adds in emulsifying pot by step 5 and step 6 material, stirs 5 minutes; Add Methylisothiazolinone 0.00288 kg to continue to stir with essence 0.00045 kg phase;
(11) sample, analyze; Do discharging to prepare, sterilization discharge tank, opens uviol lamp, irradiates 10 minutes simultaneously;
(12) treat that temperature reduces to 40 DEG C, after sample analysis result is qualified, discharging;
(13) material taken the dish out of the pot pushes rest chamber, ageing fill afterwards in 12 hours, packaging.
Embodiment 2
The manufacture method of acne eliminating cream realizes according to the following steps:
(1) American Avocado Tree oil 0.02662 kg, squalane 0.01771 kg, Miglyol 812 0.05324 kg, dimethicone 0.02662 kg, EMT-100.02662 kg, Olivem 10000.01771 kg, almond oil 0.03553 kg, bisabolol 0.00352 kg, Vitamin E acetate 0.00352 kg put into oil cauldron and mix, heating-up temperature 80 DEG C ± 2 DEG C, constant temperature stirs 10 minutes, stirring and dissolving is even, stand-by;
(2) glycerol 0.10127 kg and xanthan gum 0.00264 kg mixes, and stirs, stand-by;
(3) deionized water A0.9 kg is added in kettle, open stirring, the material in step 2 is added, stir, start heating, then Sargassum spirit 0.3909 kg, allantoin 0.00528 kg, triclosan 0.00176 kg are added in kettle, temperature controls at 85 DEG C ± 2 DEG C, stand-by;
(4) heating emulsification pot, about temperature 45 C, evacuation, vacuum remains on 0.05Mpa.
(5) arbutin 0.05324 kg, deionized water B0.05324 kg mix, and temperature is no more than 45 DEG C, and stirring and dissolving is even.Stand-by;
(6) 1, ammediol 0.10127 kg, Gherkin extract 0.01067 kg, hamamelis extract 0.01419 kg, Radix Salviae Miltiorrhizae extract 0.00891 kg, little Flos Chrysanthemi extract 0.00891 kg, wheat malt germ extract 0.08106 kg mix, temperature is no more than 45 DEG C, stirring and dissolving is even, stand-by;
(7) will meet the requirements of in oil cauldron material suction emulsifying pot, open stirring, mixing speed 300rpm, temperature 80 DEG C ± 1 DEG C;
(8) rapidly by kettle material suction emulsifying pot, mixing speed brings up to 500rpm, opens homogenizer, homogenizing speed 1800rpm, treats that material all exhausts, and homogenizing speed brings up to 2000rpm, homogenizing time 6 minutes.Homogenizing terminates, and constant temperature stirs 10 minutes;
(9) lower the temperature, open the cooling water of emulsifying pot, cooling rate 3 DEG C/2 minutes, treats that temperature reduces to 70 DEG C, again opens homogenizer, homogenizing speed 1800rpm, homogenizing time 3 minutes;
(10) treat that temperature reduces to 60 DEG C, add sheath stamen oil 0.01771 kg, mixing speed reduces to 400rpm; Temperature reduces to 45 DEG C, all adds in emulsifying pot by step 5 and step 6 material, stirs 5 minutes; Add Methylisothiazolinone 0.00352 kg to continue to stir with essence 0.00055 kg phase;
(11) sample, analyze; Do discharging to prepare, sterilization discharge tank, opens uviol lamp, irradiates 10 minutes simultaneously;
(12) treat that temperature reduces to 40 DEG C, after sample analysis result is qualified, discharging;
(13) material taken the dish out of the pot pushes rest chamber, ageing fill afterwards in 12 hours, packaging.

Claims (2)

1. an acne eliminating cream, is characterized in that: the raw material comprised, and is 1 ultimate unit with deionized water A, deionized water A and American Avocado Tree oil, squalane, Miglyol 812, dimethicone, EMT-10, Olivem 1000, almond oil, bisabolol, Vitamin E acetate, glycerol, xanthan gum, Sargassum spirit, allantoin, triclosan, sheath stamen oil, arbutin, deionized water B, 1,3-PD, Gherkin extract, hamamelis extract, Radix Salviae Miltiorrhizae extract, little Flos Chrysanthemi extract, wheat malt germ extract, the mass ratio of Methylisothiazolinone and essence is 1:0.02178 ~ 0.02662, 1:0.01449 ~ 0.01771,1:0.04356 ~ 0.05324,1:0.02178 ~ 0.02662,1:0.02178 ~ 0.02662,1:0.01449 ~ 0.01771,1:0.02907 ~ 0.03553,1:0.00288 ~ 0.00352,1:0.00288 ~ 0.00352,1:0.06013 ~ 0.10127,1:0.00216 ~ 0.00264,1:0.02551 ~ 0.03909,1:0.00432 ~ 0.00528,1:0.00144 ~ 0.00176,1:0.01449 ~ 0.01771,1:0.04356 ~ 0.05324,1:0.04356 ~ 0.05324,1:0.06013 ~ 0.10127,1:0.00873 ~ 0.01067,1:0.01161 ~ 0.01419,1:0.00729 ~ 0.00891,1:0.00729 ~ 0.00891,1:0.04814 ~ 0.08106,1:0.00288 ~ 0.00352,1:0.00045 ~ 0.00055.
2. an acne eliminating cream, it is characterized in that: (1) American Avocado Tree oil, squalane, Miglyol 812, dimethicone, EMT-10, Olivem 1000, almond oil, bisabolol, Vitamin E acetate are put into oil cauldron and mixed, heating-up temperature 80 DEG C ± 2 DEG C, constant temperature stirs 10 minutes, stirring and dissolving is even, stand-by;
(2) glycerol and xanthan gum mixing, stir, stand-by;
(3) add in kettle by deionized water A, open stirring, added by the material in step 2, stir, start heating, then add in kettle by Sargassum spirit, allantoin, triclosan, temperature controls at 85 DEG C ± 2 DEG C, stand-by;
(4) heating emulsification pot, about temperature 45 C, evacuation, vacuum remains on 0.05Mpa;
(5) arbutin, deionized water B mix, and temperature is no more than 45 DEG C, and stirring and dissolving is even, stand-by;
(6) 1,3-PD, Gherkin extract, hamamelis extract, Radix Salviae Miltiorrhizae extract, little Flos Chrysanthemi extract, wheat malt germ extract mixing, temperature is no more than 45 DEG C, and stirring and dissolving is even, stand-by;
(7) will meet the requirements of in oil cauldron material suction emulsifying pot, open stirring, mixing speed 300rpm, temperature 80 DEG C ± 1 DEG C;
(8) rapidly by kettle material suction emulsifying pot, mixing speed brings up to 500rpm, opens homogenizer, homogenizing speed 1800rpm, treats that material all exhausts, and homogenizing speed brings up to 2000rpm, homogenizing time 6 minutes, and homogenizing terminates, and constant temperature stirs 10 minutes;
(9) lower the temperature, open the cooling water of emulsifying pot, cooling rate 3 DEG C/2 minutes, treats that temperature reduces to 70 DEG C, again opens homogenizer, homogenizing speed 1800rpm, homogenizing time 3 minutes;
(10) treat that temperature reduces to 60 DEG C, add sheath stamen oil, mixing speed reduces to 400rpm; Temperature reduces to 45 DEG C, all adds in emulsifying pot by step 5 and step 6 material, stirs 5 minutes; Add Methylisothiazolinone to continue mutually to stir with essence;
(11) sample, analyze; Do discharging to prepare, sterilization discharge tank, opens uviol lamp, irradiates 10 minutes simultaneously;
(12) treat that temperature reduces to 40 DEG C, after sample analysis result is qualified, discharging;
(13) material taken the dish out of the pot pushes rest chamber, ageing fill afterwards in 12 hours, packaging.
CN201310735163.XA 2013-12-28 2013-12-28 Anti-acne cream and preparation method thereof Pending CN104739686A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106420792A (en) * 2016-09-21 2017-02-22 百奥迈科生物技术有限公司 Micro-nucleic acid acne-removing compound
CN110063925A (en) * 2019-03-19 2019-07-30 广东医科大学 A kind of acne-removing composition and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106420792A (en) * 2016-09-21 2017-02-22 百奥迈科生物技术有限公司 Micro-nucleic acid acne-removing compound
WO2018054229A1 (en) * 2016-09-21 2018-03-29 百奥迈科生物技术有限公司 Micro-nucleic acid acne-removing composition
CN110063925A (en) * 2019-03-19 2019-07-30 广东医科大学 A kind of acne-removing composition and preparation method thereof

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Application publication date: 20150701