CN105342889A - Acne removing cream and method for preparing same - Google Patents

Acne removing cream and method for preparing same Download PDF

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Publication number
CN105342889A
CN105342889A CN201510848515.1A CN201510848515A CN105342889A CN 105342889 A CN105342889 A CN 105342889A CN 201510848515 A CN201510848515 A CN 201510848515A CN 105342889 A CN105342889 A CN 105342889A
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eliminating cream
phase
acne eliminating
under
component
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陈海珍
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Zhuhai Leiteen International Trade Co Ltd
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Zhuhai Leiteen International Trade Co Ltd
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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Abstract

The invention relates to acne removing cream and a method for preparing the same. The acne removing cream comprises, by weight, steareth-2, lauroyl glutamate, steareth-21, cetyl alcohol, glyceryl stearate, dimethicone, isomerization cetane, capric triglyceride, isopalmitic acid ethylhexyl acrylate, vitamin E, bisabolol, propylene glycol, dipotassium glycyrrhizinate, butanediol, hexamidine (hydroxyethanesulphonic acid) dibasic, EDTA (ethylene diamine tetraacetic acid)-disodium, water, matrine, preservatives, asiaticoside, pH (potential of hydrogen) regulators and thickeners. The acne removing cream and the method have the advantages that various raw materials are mixed with one another, and accordingly facial skin cleaning and care effects can be realized; pimple, acne, papule, pustule and the like on the faces of users can be effectively removed.

Description

Acne eliminating cream and preparation method thereof
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of acne eliminating cream and preparation method thereof.
Background technology
Anti-acne is the process using Medical Technology or method to eliminate pox, and pox is cried again " skin sore " or " acne ", is a kind of dermatosis because hair follicle and sebaceous gland obstruction, inflammation cause.During adolescence, the hormone meeting stimulating hair growth in body, promote smegma more heavy wool fat, therefore hair and sebaceous gland pile up many materials.In order to cater to the demand of the vast personage that likes to be beautiful, product for resolving poxes on the market gets more and more at present, but uses the composition such as hormone, antibiotic in a lot of product for resolving poxes, and zest is larger, easily causes skin to the drug resistance of Propiobacterium.
Chinese patent CN1486684A discloses a kind of acne eliminating cream, and this acne eliminating cream is made up of natural medicinal plant Rhizoma Ligustici, surfactant, solvent, auxiliary agent, rubber polymer and adjuvant: the preparation method of this acne eliminating cream is: first adopt conventional method to prepare after crude extract, effective site ethyl acetate extract or volatile oil mix with surfactant, auxiliary agent, adjuvant plant Rhizoma Ligustici and obtain component A; Rubber polymer is dissolved in solvent and obtains B component; Again B component is under agitation joined in component A, be chilled to room temperature, emulsifying, radiosterilization, subpackage.
Chinese patent CN104739686A discloses a kind of acne eliminating cream, this acne eliminating cream comprises following raw material: deionized water A, American Avocado Tree oil, squalane, Caprylic Capric fat, dimethicone, EMT-10,01ivem1000, almond oil, bisabolol, Vitamin E acetate, glycerol, xanthan gum, Sargassum spirit, allantoin, triclosan, sheath stamen oil, arbutin, deionized water B, 1,3-PD, Gherkin extract, hamamelis extract, Radix Salviae Miltiorrhizae extract, little Flos Chrysanthemi extract, wheat malt germ extract, Methylisothiazolinone and essence.
Summary of the invention
In order to solve the problem that acne eliminating cream anti-acne in prior art not exclusively has pox to print, the invention provides a kind of energy anti-acne and acne eliminating cream of pox print and preparation method thereof can be removed.
The technical solution adopted in the present invention is:
A kind of acne eliminating cream, comprises following raw material: component A, B component, matrine, antiseptic, asiaticoside, pH adjusting agent, thickening agent;
Described component A comprises: stereth-2, lauroyl glutamate ester, stereth-21, spermol, glyceryl stearate, dimethicone, isomery hexadecane, tricaprin, different ethylhexyl palmitate, vitamin E, bisabolol;
Described B component comprises: propylene glycol, glycyrrhizic acid dipotassium, butanediol, hexamidine two (hydroxyethylsulfonic acid .) salt, EDTA-disodium, water.
Further, a kind of acne eliminating cream, comprises the raw material of following weight parts: stereth-20.75-3 part, lauroyl glutamate ester 0.75-3 part, stereth-211-4 part, spermol 1.5-6 part, glyceryl stearate 0.5-3 part, dimethicone 0.5-3 part, isomery hexadecane 2-8 part, tricaprin 1-4 part, different ethylhexyl palmitate 1-4 part, vitamin E 0.25-1 part, bisabolol 0.25-1 part; Propylene glycol 2-8 part, glycyrrhizic acid dipotassium 0.1-0.4 part, butanediol 2.5-10 part, hexamidine two (hydroxyethylsulfonic acid .) salt 0.08-0.3 part, EDTA-disodium 0.025-0.1 part, water 10-15 part, matrine 0.2-0.8 part, antiseptic 0.075-0.3 part, asiaticoside 0.25-1 part, pH adjusting agent 0.25-1 part, thickening agent 0.5-2 part.
Further, described antiseptic is the mixture of Methylisothiazolinone and benzene isothiazolone; Described pH adjusting agent is triethanolamine; Described thickening agent is polyacrylamide, laureth-7 and C 13-14the mixture of isoparaffin.
Further, the preparation method of above-mentioned acne eliminating cream comprises the following steps:
(1) by admixed together for each raw material of component A, heat and stir, obtaining A phase;
(2) in emulsifying pot, add B component, heat and stir, obtain B phase;
(3) be added to by A in B phase, mixing and stirring obtains A, B mixed phase;
(4) in A, B mixed phase, add other raw materials and stir, obtaining mixed material:
(5) mixed material is stored a period of time in sterilizing room, adjust ph, obtain acne eliminating cream.
Preferably, in step (1) by component A under the condition of 80-85 DEG C, constant temperature stir 8-12min, obtain A phase; In step (2) by B component under the condition of 83-87 DEG C, constant temperature stir 12-17min, obtain B phase.
Preferably, in step (3), in emulsifying pot, vacuum is by A phase suction emulsifying pot under the condition of 0.6MPa-0.8MPa, and is stir 12-17min under the condition of 50-60r/min at rotating speed, obtains A, B mixed phase.Before in A phase suction emulsifying pot, still keep stirring to B phase.
Preferably, be under the stirring of 2600-3000r/min at rotating speed, with homogenizer by A, B mixed phase homogenizing 15-18min, again under the stirring of 200-300r/min, homogenizing 8-12 minute, is then down to 50-55 DEG C by the temperature in emulsifying pot, then adds other raw materials in A, B mixed phase.Homogenizing process is carried out to A, B mixed phase, relatively good in order to ensure the emulsifying effectiveness of mixed phase.The air intake valve of emulsifying pot to be opened after high-speed stirred homogenizing, froth breaking is carried out to A, B mixed phase, and then stirring at low speed homogenizing.
Preferably, also comprise the step of step (4) gained compound being carried out to homogenizing process, be homogenizing 8-12min under the condition of 0.6MPa-0.8MPa in vacuum by gained mixed material, low whipping speed is under the condition of 50-60r/min again, mixed material is cooled to 40-45 DEG C, close and stir, leave standstill 10-12min.After homogenizing process, open the air intake valve of emulsifying pot, carry out defoaming treatment.
Preferably, mixed material is stored 24-28h in (5) by step in sterilizing room, regulates pH between 6-6.5, obtains acne eliminating cream.
Preferably, A, B mixed phase is in the process of homogenizing, and the temperature in emulsifying pot is 80-85 DEG C.
Beneficial effect of the present invention is:
Each raw material mixes by acne eliminating cream of the present invention, can play effect that is clean, nursing to skin of face; Effectively can remove the comedo, acne, pimple, pustule etc. of face.Life-time service acne eliminating cream of the present invention can play pox by Peppermint Extract prevention face, and what face was become is smooth and fine and smooth.In addition acne eliminating cream of the present invention uses and compares aspect, only needs after clean, is applied in face, does not need cleaning.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
In the present invention, if not refer in particular to, all parts are unit of weight g, and all raw materials etc. all can be buied from market or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
Embodiment 1
A kind of acne eliminating cream, comprises the raw material of following weight parts:
Component A: stereth-20.75 parts, lauroyl glutamate ester 0.75 part, stereth-211 parts, spermol 1.5 parts, glyceryl stearate 0.5 part, dimethicone 0.5 part, isomery hexadecane 2 parts, tricaprin 1 part, different ethylhexyl palmitate 1 part, vitamin E 0.25 part, bisabolol 0.25 part;
B component: propylene glycol 2 parts, glycyrrhizic acid dipotassium 0.1 part, butanediol 2.5 parts, hexamidine two (hydroxyethylsulfonic acid .) salt 0.08 part, EDTA-disodium 0.025 part, 10 parts, water;
Matrine 0.2 part, Methylisothiazolinone 0.0075 part, benzene isothiazolone 0.0675 part, asiaticoside 0.25 part, triethanolamine 0.25 part, polyacrylamide, laureth-7 and C 13-14totally 0.5 part, the mixture of isoparaffin.
The preparation method of above-mentioned acne eliminating cream comprises the following steps:
(1) by component A under the condition of 80 DEG C, constant temperature stir 8min, obtain A phase;
(2) in emulsifying pot, add B component, and by B component under the condition of 83 DEG C, constant temperature stirs 12min, obtains B phase;
(3) vacuum in emulsifying pot being adjusted to 0.6MPa, by A phase under the condition of this negative pressure in suction emulsifying pot, and is stir 12min under the condition of 50r/min at rotating speed.
(4) at rotating speed be 2600r/min stirring under, with homogenizer by A, B mixed phase homogenizing 15min, temperature during this period of time in emulsifying pot remains on 80 DEG C, again under the stirring of 200r/min, homogenizing 8 minutes, the temperature equally during this period of time in emulsifying pot remains on 80 DEG C, then the temperature in emulsifying pot is down to 50 DEG C, in A, B mixed phase, add other raw materials again, stir to obtain mixed material.
(5) homogenizing process is carried out to step (4) gained compound, be homogenizing 8min under the condition of 0.6MPa in vacuum by gained mixed material, after homogenizing process, open the air intake valve of emulsifying pot, carry out defoaming treatment, then low whipping speed is under the condition of 50r/min, mixed material is cooled to 40 DEG C, close and stir, leave standstill 10min.
(6) mixed material after homogenizing process is stored 24h in sterilizing room, regulate pH to be 6, obtain acne eliminating cream.
Embodiment 2
A kind of acne eliminating cream, comprises the raw material of following weight parts:
Component A: stereth-21.5 parts, lauroyl glutamate ester 1.5 parts, stereth-212 parts, spermol 3 parts, glyceryl stearate 1.5 parts, dimethicone 1.5 parts, isomery hexadecane 4 parts, tricaprin 2 parts, different ethylhexyl palmitate 2 parts, vitamin E 0.5 part, bisabolol 0.5 part;
B component: propylene glycol 4 parts, glycyrrhizic acid dipotassium 0.2 part, butanediol 5 parts, hexamidine two (hydroxyethylsulfonic acid .) salt 0.2 part, EDTA-disodium 0.05 part, 12 parts, water;
Matrine 0.4 part, Methylisothiazolinone 0.007 part, benzene isothiazolone 0.07 part, asiaticoside 0.5 part, triethanolamine 0.5 part, polyacrylamide, laureth-7 and C 13-14totally 1 part, the mixture of isoparaffin.
The preparation method of above-mentioned acne eliminating cream comprises the following steps:
(1) by component A under the condition of 82 DEG C, constant temperature stir 10min, obtain A phase;
(2) in emulsifying pot, add B component, and by B component under the condition of 85 DEG C, constant temperature stirs 15min, obtains B phase;
(3) vacuum in emulsifying pot being adjusted to 0.7MPa, by A phase under the condition of this negative pressure in suction emulsifying pot, and is stir 15min under the condition of 55r/min at rotating speed.
(4) at rotating speed be 2800r/min stirring under, with homogenizer by A, B mixed phase homogenizing 16min, temperature during this period of time in emulsifying pot remains on 82 DEG C, again under the stirring of 250r/min, homogenizing 10 minutes, the temperature equally during this period of time in emulsifying pot remains on 82 DEG C, then the temperature in emulsifying pot is down to 52 DEG C, in A, B mixed phase, add other raw materials again, stir to obtain mixed material.
(5) homogenizing process is carried out to step (4) gained compound, be homogenizing 10min under the condition of 0.7MPa in vacuum by gained mixed material, after homogenizing process, open the air intake valve of emulsifying pot, carry out defoaming treatment, then low whipping speed is under the condition of 55r/min, mixed material is cooled to 43 DEG C, close and stir, leave standstill 11min.
(6) mixed material after homogenizing process is stored 26h in sterilizing room, regulate pH to be 6.3, obtain acne eliminating cream.
Embodiment 3
A kind of acne eliminating cream, comprises the raw material of following weight parts:
Component A: stereth-23 parts, lauroyl glutamate ester 3 parts, stereth-214 parts, spermol 6 parts, glyceryl stearate 3 parts, dimethicone 3 parts, isomery hexadecane 8 parts, tricaprin 4 parts, different ethylhexyl palmitate 4 parts, vitamin e1 part, bisabolol 1 part;
B component: propylene glycol 8 parts, glycyrrhizic acid dipotassium 0.4 part, butanediol 10 parts, hexamidine two (hydroxyethylsulfonic acid .) salt 0.3 part, EDTA-disodium 0.1 part, 15 parts, water;
Matrine 0.8 part, Methylisothiazolinone 0.0013 part, benzene isothiazolone 0.2987 part, asiaticoside 1 part, triethanolamine 1 part, polyacrylamide, laureth-7 and C 13-14totally 2 parts, the mixture of isoparaffin.
The preparation method of above-mentioned acne eliminating cream comprises the following steps:
(1) by component A under the condition of 85 DEG C, constant temperature stir 12min, obtain A phase;
(2) in emulsifying pot, add B component, and by B component under the condition of 87 DEG C, constant temperature stirs 17min, obtains B phase;
(3) vacuum in emulsifying pot being adjusted to 0.8MPa, by A phase under the condition of this negative pressure in suction emulsifying pot, and is stir 17min under the condition of 50r/min at rotating speed.
(4) at rotating speed be 3000r/min stirring under, with homogenizer by A, B mixed phase homogenizing 18min, temperature during this period of time in emulsifying pot remains on 85 DEG C, again under the stirring of 300r/min, homogenizing 12 minutes, the temperature equally during this period of time in emulsifying pot remains on 85 DEG C, then the temperature in emulsifying pot is down to 55 DEG C, in A, B mixed phase, add other raw materials again, stir to obtain mixed material.
(5) homogenizing process is carried out to step (4) gained compound, be homogenizing 12min under the condition of 0.8MPa in vacuum by gained mixed material, after homogenizing process, open the air intake valve of emulsifying pot, carry out defoaming treatment, then low whipping speed is under the condition of 60r/min, mixed material is cooled to 45 DEG C, close and stir, leave standstill 12min.
(6) mixed material after homogenizing process is stored 28h in sterilizing room, regulate pH between 6.5, obtain acne eliminating cream.
The case study on implementation of embodiment 2 acne eliminating cream:
Choose the patient that 200 examples have pox and pox print on the face, after sooner or later clean, smear acne eliminating cream of the present invention, 200 routine patients the diet smeared during acne eliminating cream of the present invention and living habit with smear acne eliminating cream of the present invention before identical; Experimental result: cure 98%, effective 100%.
Cure: pox and pox print all disappear on the face;
Effective: pox disappears on the face, but pox print light again;
Invalid: pox or the basic no change of pox print on the face.
Zhang, man, 15 years old, have large area comedo on the face, this comedo length has 1 year, and smear this invention acne eliminating cream after ten days, Zhang on the face comedo disappears substantially, continues to smear this invention acne eliminating cream after one week, and Zhang's pox on the face and pox print disappear completely.
Wang, female, 17 years old, length had acne on the face, and smear this invention acne eliminating cream after one week, Wang's acne on the face disappear substantially, only leave light pockmark, continued to use this invention acne eliminating cream after one week, and Wang's pox print on the face also disappears completely.
Huang, female, 25 years old, length had large area pustule on the face, existing 6 years of this pustule, Huang smeared this invention acne eliminating cream after three weeks, and pustule is on the face desalinated substantially, continue to smear this invention acne eliminating cream after one month, Huang's pustule on the face disappears, and only leaves light pockmark.
Poplar, man, 23 years old, face is long pimple, and after smearing this invention acne eliminating cream Ninth Heaven, poplar whelk disappears.
Cloud, female, 28 years old, face is long a large amount of poxes, and smear this invention acne eliminating cream after two weeks, the pox of cloud face disappears substantially, continues to smear this invention acne eliminating cream after one week, and the pox of cloud face and pox print all disappear.
Lee, man, 29 years old, face is long a large amount of acne, and smear this invention acne eliminating cream after two weeks, Lee's acne on the face disappear most, continue to smear this invention acne eliminating cream after one week, and Lee's acne on the face disappear substantially, only left light pox print.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; though but any change is done in its details, every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.

Claims (10)

1. an acne eliminating cream, is characterized in that: comprise following raw material: component A, B component, matrine, antiseptic, asiaticoside, pH adjusting agent, thickening agent;
Described component A comprises: stereth-2, lauroyl glutamate ester, stereth-21, spermol, glyceryl stearate, dimethicone, isomery hexadecane, tricaprin, different ethylhexyl palmitate, vitamin E, bisabolol;
Described B component comprises: propylene glycol, glycyrrhizic acid dipotassium, butanediol, hexamidine two (hydroxyethylsulfonic acid .), EDTA-disodium, water.
2. acne eliminating cream according to claim 1, is characterized in that: the weight portion of described raw material is: stereth-20.75-3 part, lauroyl glutamate ester 0.75-3 part, stereth-211-4 part, spermol 1.5-6 part, glyceryl stearate 0.5-3 part, dimethicone 0.5-3 part, isomery hexadecane 2-8 part, tricaprin 1-4 part, different ethylhexyl palmitate 1-4 part, vitamin E 0.25-1 part, bisabolol 0.25-1 part; Propylene glycol 2-8 part, glycyrrhizic acid dipotassium 0.1-0.4 part, butanediol 2.5-10 part, hexamidine two (hydroxyethylsulfonic acid .) salt 0.08-0.3 part, EDTA-disodium 0.025-0.1 part, water 10-15 part, matrine 0.2-0.8 part, antiseptic 0.075-0.3 part, asiaticoside 0.25-1 part, pH adjusting agent 0.25-1 part, thickening agent 0.5-2 part.
3. acne eliminating cream according to claim 1, is characterized in that: described antiseptic is the mixture of Methylisothiazolinone and benzene isothiazolone; Described pH adjusting agent is triethanolamine; Described thickening agent is polyacrylamide, laureth-7 and C 13-14the mixture of isoparaffin.
4. the preparation method of the described acne eliminating cream of one of claim 1-3, is characterized in that: comprise the following steps:
(1) by admixed together for each raw material of component A, heat and stir, obtaining A phase;
(2) in emulsifying pot, add B component, heat and stir, obtain B phase;
(3) be added to by A in B phase, mixing and stirring obtains A, B mixed phase;
(4) in A, B mixed phase, add other raw materials and stir, obtaining mixed material;
(5) mixed material is stored a period of time in sterilizing room, adjust ph, obtain acne eliminating cream.
5. the preparation method of acne eliminating cream according to claim 4, is characterized in that; In step (1) by component A under the condition of 80-85 DEG C, constant temperature stir 8-12min, obtain A phase; In step (2) by B component under the condition of 83-87 DEG C, constant temperature stir 12-17min, obtain B phase.
6. the preparation method of acne eliminating cream according to claim 4, it is characterized in that: in step (3), in emulsifying pot, vacuum is by A phase suction emulsifying pot under the condition of 0.6MPa-0.8MPa, and be stir 12-17min under the condition of 50-60r/min at rotating speed, obtain A, B mixed phase.
7. the preparation method of acne eliminating cream according to claim 4, it is characterized in that: be under the stirring of 2600-3000r/min at rotating speed, with homogenizer by A, B mixed phase homogenizing 15-18min, again under the stirring of 200-300r/min, homogenizing 8-12 minute, then the temperature in emulsifying pot is down to 50-55 DEG C, then adds other raw materials in A, B mixed phase.
8. the preparation method of acne eliminating cream according to claim 4, it is characterized in that: also comprise the step of step (4) gained compound being carried out to homogenizing process, be homogenizing 8-12min under the condition of 0.6MPa-0.8MPa in vacuum by mixed material, low whipping speed is under the condition of 50-60r/min again, mixed material is cooled to 40-45 DEG C, close and stir, and leave standstill 10-12min.
9. the preparation method of acne eliminating cream according to claim 4, is characterized in that: mixed material is stored 24-28h in (5) by step in sterilizing room, regulates pH between 6-6.5, obtains acne eliminating cream.
10. the preparation method of acne eliminating cream according to claim 7, is characterized in that: A, B mixed phase is in the process of homogenizing, and the temperature in emulsifying pot is 80-85 DEG C.
CN201510848515.1A 2015-11-26 2015-11-26 Acne removing cream and method for preparing same Pending CN105342889A (en)

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CN105997629A (en) * 2016-05-24 2016-10-12 广州南雪药业有限公司 Acne treatment cream and preparation method thereof
CN106667852A (en) * 2017-02-28 2017-05-17 高宝化妆品(中国)有限公司 Traditional Chinese medicine cream for removing acne and preparation method thereof
CN107137281A (en) * 2017-05-27 2017-09-08 广州市千邦化妆品有限公司 A kind of anti-acne print frost and preparation method thereof
CN107184448A (en) * 2017-04-28 2017-09-22 广州瑞誉化工科技有限公司 A kind of acne eliminating cream that there is prevention pockmark to generate
CN107684530A (en) * 2017-08-25 2018-02-13 深圳市雪绒蓝天化妆品贸易有限公司 Acne-removing composition and preparation method thereof
CN107693454A (en) * 2017-11-06 2018-02-16 广州佰泰莱生物科技有限公司 A kind of plant acne eliminating cream and preparation method thereof
CN107737052A (en) * 2017-11-30 2018-02-27 林俊浩 A kind of anti-acne prints composition
CN108042641A (en) * 2017-12-26 2018-05-18 广州赛因化妆品有限公司 A kind of Chinese medicine acne eliminating cream and preparation method thereof
CN110051548A (en) * 2019-04-19 2019-07-26 广州市巨匠美容发展有限公司 A kind of ferment enzyme Deacne pack and preparation method thereof
CN111588815A (en) * 2020-05-29 2020-08-28 溯源生命科技股份有限公司 Acne-removing traditional Chinese medicine composition, application thereof and acne-removing balancing essence containing composition
CN114469822A (en) * 2020-10-23 2022-05-13 广州樱奈儿化妆品有限公司 Acne-removing repairing cream and preparation method thereof

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105997629A (en) * 2016-05-24 2016-10-12 广州南雪药业有限公司 Acne treatment cream and preparation method thereof
CN106667852A (en) * 2017-02-28 2017-05-17 高宝化妆品(中国)有限公司 Traditional Chinese medicine cream for removing acne and preparation method thereof
CN107184448A (en) * 2017-04-28 2017-09-22 广州瑞誉化工科技有限公司 A kind of acne eliminating cream that there is prevention pockmark to generate
CN107137281A (en) * 2017-05-27 2017-09-08 广州市千邦化妆品有限公司 A kind of anti-acne print frost and preparation method thereof
CN107684530A (en) * 2017-08-25 2018-02-13 深圳市雪绒蓝天化妆品贸易有限公司 Acne-removing composition and preparation method thereof
CN107693454A (en) * 2017-11-06 2018-02-16 广州佰泰莱生物科技有限公司 A kind of plant acne eliminating cream and preparation method thereof
CN107737052A (en) * 2017-11-30 2018-02-27 林俊浩 A kind of anti-acne prints composition
CN108042641A (en) * 2017-12-26 2018-05-18 广州赛因化妆品有限公司 A kind of Chinese medicine acne eliminating cream and preparation method thereof
CN110051548A (en) * 2019-04-19 2019-07-26 广州市巨匠美容发展有限公司 A kind of ferment enzyme Deacne pack and preparation method thereof
CN111588815A (en) * 2020-05-29 2020-08-28 溯源生命科技股份有限公司 Acne-removing traditional Chinese medicine composition, application thereof and acne-removing balancing essence containing composition
CN114469822A (en) * 2020-10-23 2022-05-13 广州樱奈儿化妆品有限公司 Acne-removing repairing cream and preparation method thereof

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