CN108158938A - A kind of Pimple removing scream of the ingredient containing American cockroach and preparation method thereof - Google Patents
A kind of Pimple removing scream of the ingredient containing American cockroach and preparation method thereof Download PDFInfo
- Publication number
- CN108158938A CN108158938A CN201810150897.4A CN201810150897A CN108158938A CN 108158938 A CN108158938 A CN 108158938A CN 201810150897 A CN201810150897 A CN 201810150897A CN 108158938 A CN108158938 A CN 108158938A
- Authority
- CN
- China
- Prior art keywords
- extract
- cockroach
- american
- noni
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
Abstract
The present invention discloses Pimple removing scream of a kind of ingredient containing American cockroach and preparation method thereof, includes the raw material of following masses percentage：American-cockroach-extract：2 10%, Gotu Kola P.E：1 10%, Noni extract：1 10%, olive essential oil：0.1 1%, vitamin E：1 6%, medical ventolin：5 20%, glycerol stearate：2.5 4.5%, glycerine：2 6%, Sodium Hyaluronate：0.5 5%, allantoin：0.2 1%, EDETATE SODIUM：0.1 1%, Kathon：0‑0.04%.Pimple removing scream provided by the invention can not only treat the whelk of skin face, promote tissue repair, anti-oxidant, can also there is the effect of moisturizing whitening nourishes rough skin.It is quick, face acne, acne quick, safe and effective can be dispelled, repairs acne print, removes skin silting, sterilize anti-inflammatory, and without hormone, long-time service is without side-effects, is not easy repeatedly.
Description
Technical field
The present invention relates to a kind of face creams for treating whelk, and in particular to a kind of Pimple removing scream of ingredient containing American cockroach and
Preparation method.
Background technology
As people's living standard is continuously improved, people more focus on the quality and safety of cosmetic raw materials, youth
Acne is to betide the sebaceous glands chronic disease of puberty and manhood, mainly appears on the face and chest and back of youth of both sexes, shape
Into damages such as acne, papule, warts, tubercle, tumours, majority of populations can leave pockmark, more there is the consumer of whelk
Wish to use and there is moisturizing whitening, the face cream of small effect to skin irritation, and existing Pimple removing scream on the market, raw material is mostly
Using chemical raw material, anti-acne effect is undesirable, also big to skin damage, for face cream this product prior art Shortcomings it
Place, be exactly face cream making in, most products exist to lack and have the strong for the treatment of whelk simultaneously using with cosmetology effect
The problem of raw material of the harmless green natural of health.
Invention content
To solve the above-mentioned problems in the prior art, the present invention provides a kind of Pimple removing scream of the ingredient containing American cockroach
And preparation method thereof, it is the Pimple removing scream made of effective component extracting from American cockroach and Chinese herbal medicine, for usual face
White moisturizing moisturizing, while the whelk of puberty and manhood can also be treated.
To achieve these goals, the present invention is achieved through the following technical solutions：A kind of anti-acne of the ingredient containing American cockroach
Face cream includes the raw material of following masses percentage：
American-cockroach-extract：2-10%, Gotu Kola P.E：1-10%, Noni extract：1-10%, olive essential oil：0.1-
1%, vitamin E：1-6%, medical ventolin：5-20%, glycerol stearate：2.5-4.5%, glycerine：2-6%, Sodium Hyaluronate：
0.5-5%, allantoin：0.2-1%, EDETATE SODIUM：0.1-1%, Kathon：0-0.04%, deionized water：Surplus；Above-mentioned each component
Summation is 100%.
Another object of the present invention is to provide a kind of preparation method of the Pimple removing scream of ingredient containing American cockroach, under
Arrange each step：
（1）By the material preparation of following mass percent：
American-cockroach-extract：2-10%, Gotu Kola P.E：1-10%, Noni extract：1-10%, olive essential oil：0.1-
1%, vitamin E：1-6%, medical ventolin：5-20%, glycerol stearate：2.5-4.5%, glycerine：2-6%, Sodium Hyaluronate：
0.5-5%, allantoin：0.2-1%, EDETATE SODIUM：0.1-1%, Kathon：0-0.04%, deionized water：Surplus；Above-mentioned each component
Summation is 100%；
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, mixed material A is obtained, treats
When 40 DEG C are down at a temperature of mixed material A, glycerine and Sodium Hyaluronate are added in, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
The American-cockroach-extract uses alcohol precipitation water extraction, by following operation：
A, the full strong adult bombay canary of polypide is selected, is placed in dryer and is toasted with 70-80 DEG C, is dried to completely
After drying, by the use of ethyl alcohol as solvent, 1 is counted according to solid-liquid ratio g/ml:（7-9）, impregnated 2 months, obtained with the ethyl alcohol of concentration 95v/v%
To mixture；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
The Gotu Kola P.E is made by following operation：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
The Noni extract is made by following operation：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:（6-10）, by the use of the ethyl alcohol of a concentration of 75v/v% as molten
Agent obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract through vacuum distillation.
Wherein, the big Lian extracts of U.S. Lian are water-soluble medicinal extract, and the Gotu Kola P.E is alcohol extract medicinal extract, described
Noni extract is alcohol extracting without medicinal extract, and the vitamin E is a kind of liposoluble vitamin, clear viscous liquids, hydrolysis production
Object is tocopherol, is one of most important antioxidant, and the glycerol stearate is generally solid, semisolid or viscous crude shape
Liquid.It is in heat resistance, viscosity etc. compared with polyol fatty acid ester height, and hydrolysis is good, has very strong emulsifiability, and tool is special
Stability, thermal stability and Viscosity-reducing very strong can reduce the surface tension of water, form micella, have moistening, infiltration, expand
Dissipate, antioxygen, viscosity-adjusting agent, sterilize, prevent aging, etc. it is multi-functional, itself is safe and nontoxic, nontoxic to human body.Its automatic emulsifying performance
Good, can be used alone can also be used in compounding with other emulsifiers, and the glycerine is colourless sweet clear and bright thick liquid.It is odorless.
As solvent, lubricant, medicament, the Sodium Hyaluronate is the substance extracted from cockscomb, can also be fermented by Lactococcus
It is made, for white or off-white color particle or powder, odorless is for products such as cream, frost, honey, milk, facial mask, the shampoos of cosmetics
In, it to keep the moisture of skin, hair, moisturizes the skin, increases gloss, and the generation of chapped skin and wrinkle can be prevented.It is described
Allantoin is a kind of nontoxic, tasteless and nonirritant, without hypersensitive white crystal, and allantoin is a kind of amphoteric compound, can be tied
Close many kinds of substance formed double salt, have be protected from light, sterilization and anticorrosion, analgesic, antioxidation, can make skin keep moisture content, moisten and
Softness, the EDETATE SODIUM are a kind of important complexing agents, are mainly used for that ferrous ion is complexed, and control polymerization rate, described
Kathon is light amber transparency liquid, and smell is mild, is mainly used for cosmetics anti-corrosion, due to toxicity is low, antibacterial action range is wide,
Effect is strong and cosmetic material compatibility is good, and can be dissolved in water, easy to use.Glycerine is with Sodium Hyaluronate also as increasing
Thick dose, vitamin E and olive essential oil also act as antioxidation, and Kathon is preservative.
American cockroach category Insecta Blattaria Blattidae Periplaneta, is commonly called as cockroach, American cockroach is traditional Chinese medicine, is entered
Medicine first recorded in《Sheng Nong's herbal classic》Middle product are listed in, the modern times show that it, with resisting oxidation free radical, promotes the pharmacology such as tissue repair
Effect, centella perennial herb, nature and flavor：It is bitter, pungent, it is cold in nature, and centella can inhibit proliferation of fibrous tissue：Asiaticosid energy
Inhibit collagenous fibres, have the function of to inhibit proliferation of fibrous tissue, promote skin growth, and play the role of inhibiting skin ulcer,
Noni fruit is the fruit of beach wood Morinda offcinalis How.Its fruit has the composition rich in human body cell body cell, there is the effect of salubrity, Nuo Li
Berry extract is safe natural, and vitamin E Green Tea Extract oxidation is additionally added in formula, can not only be resisted
Damage of the free radical to skin, and wound healing can be promoted, inhibit skin aging, a variety of Chinese herbal medicine interworkings, with reference to America
The effect of Lian is anti-inflammatory antibacterial greatly, treatment whelk not only can be with treating both manifestation and root cause of disease, while also has and accomplish to nourish, moisturizing, the work(of whitening
Effect.
The advantages of present invention has and effect：Pimple removing scream provided by the invention can not only treat the youth of skin face
Acne promotes tissue repair, anti-oxidant, can also there is the effect of moisturizing whitening nourishes rough skin.Pimple removing scream provided by the invention is shown in
Effect is fast, quick, safe and effective can dispel face acne, acne, repair acne print, remove skin silting, and sterilize anti-inflammatory, to red
Swollen, distending pain inflammatory small pox is also releived effect, is effective against the whelk for the treatment of puberty and manhood, with anti-acne,
Moisturizing, the effect of light acne print but also moisturizing skin whitening effect can be played, make skin that clean bright gloss be presented.And without sharp
Element, long-time service is without side-effects, is not easy repeatedly.
Specific implementation method
The invention will be further described with reference to embodiments.
Embodiment 1
（1）By the material preparation of following mass percent：
American-cockroach-extract：2%, Gotu Kola P.E：1%, Noni extract：1%, olive essential oil：0.1%, vitamin E：
1%, medical ventolin：5%, glycerol stearate：2.5%, glycerine：2%, Sodium Hyaluronate：1%, allantoin：0.2%, EDTA bis-
Sodium：0.1%, deionized water：Surplus；The summation of above-mentioned each component is 100%；
The American-cockroach-extract uses alcohol precipitation water extraction, by following operation：
A, the full strong adult bombay canary of polypide is selected, is placed in dryer and is toasted with 75 DEG C, is dried to completely dry
After dry, by the use of ethyl alcohol as solvent, 1 is counted according to solid-liquid ratio g/ml:8, it is impregnated 2 months, is mixed with the ethyl alcohol of concentration 95v/v%
Object；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
The Gotu Kola P.E is made by following operation：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
The Noni extract is made by following operation：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:8, by the use of the ethyl alcohol of a concentration of 75v/v% as solvent, pass through
Vacuum distillation obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract.
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, obtains mixed material
A when being down to 40 DEG C at a temperature of material A to be mixed, adds in glycerine and Sodium Hyaluronate, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
Embodiment 2
（1）By the material preparation of following mass percent：
American-cockroach-extract：4%, Gotu Kola P.E：2%, Noni extract：2%, olive essential oil：0.2%, vitamin E：
1%, medical ventolin：7%, glycerol stearate：3%, glycerine：3%, Sodium Hyaluronate：1.5%, allantoin：0.3%, EDTA bis-
Sodium：0.2%, Kathon：0.01%, deionized water：Surplus；The summation of above-mentioned each component is 100%；
The American-cockroach-extract uses alcohol precipitation water extraction, by following operation：
A, the full strong adult bombay canary of polypide is selected, is placed in dryer and is toasted with 70 DEG C, is dried to completely dry
After dry, by the use of ethyl alcohol as solvent, 1 is counted according to solid-liquid ratio g/ml:7, it is impregnated 2 months, is mixed with the ethyl alcohol of concentration 95v/v%
Object；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
The Gotu Kola P.E is made by following operation：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
The Noni extract is made by following operation：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:6, by the use of the ethyl alcohol of a concentration of 75v/v% as solvent, pass through
Vacuum distillation obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract.
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, obtains mixed material
A when being down to 40 DEG C at a temperature of material A to be mixed, adds in glycerine and Sodium Hyaluronate, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
Embodiment 3
（1）By the material preparation of following mass percent：
American-cockroach-extract：6%, Gotu Kola P.E：3%, Noni extract：3%, olive essential oil：0.3%, vitamin E：
3%, medical ventolin：9%, glycerol stearate：3.5%, glycerine：4%, Sodium Hyaluronate：2%, allantoin：0.6%, EDTA bis-
Sodium：0.3%, Kathon：0.02%, deionized water：Surplus；The summation of above-mentioned each component is 100%；
The American-cockroach-extract uses alcohol precipitation water extraction, by following operation：
A, the full strong adult bombay canary of polypide is selected, is placed in dryer and is toasted with 80 DEG C, is dried to completely dry
After dry, by the use of ethyl alcohol as solvent, 1 is counted according to solid-liquid ratio g/ml:9, it is impregnated 2 months, is mixed with the ethyl alcohol of concentration 95v/v%
Object；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
The Gotu Kola P.E is made by following operation：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
The Noni extract is made by following operation：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:10, by the use of the ethyl alcohol of a concentration of 75v/v% as solvent, pass through
Vacuum distillation obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract.
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, obtains mixed material
A when being down to 40 DEG C at a temperature of material A to be mixed, adds in glycerine and Sodium Hyaluronate, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
Embodiment 4
（1）By the material preparation of following mass percent：
American-cockroach-extract：8%, Gotu Kola P.E：10%, Noni extract：10%, olive essential oil：1%, vitamin E：
4%, medical ventolin：1-11%, glycerol stearate：4%, glycerine：5%, Sodium Hyaluronate：3%, allantoin：0.8%, EDTA bis-
Sodium：1%, Kathon：0.03%, deionized water：Surplus；The summation of above-mentioned each component is 100%；
The American-cockroach-extract uses alcohol precipitation water extraction, by following operation：
A, the full strong adult bombay canary of polypide is selected, is placed in dryer and is toasted with 78 DEG C, is dried to completely dry
After dry, by the use of ethyl alcohol as solvent, 1 is counted according to solid-liquid ratio g/ml:8, it is impregnated 2 months, is mixed with the ethyl alcohol of concentration 95v/v%
Object；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
The Gotu Kola P.E is made by following operation：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
The Noni extract is made by following operation：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:9, by the use of the ethyl alcohol of a concentration of 75v/v% as solvent, pass through
Vacuum distillation obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract.
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, obtains mixed material
A when being down to 40 DEG C at a temperature of material A to be mixed, adds in glycerine and Sodium Hyaluronate, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
Embodiment 5
（1）By the material preparation of following mass percent：
American-cockroach-extract：10%, Gotu Kola P.E：5%, Noni extract：5%, olive essential oil：1%, vitamin E：
6%, medical ventolin：20%, glycerol stearate：4.5%, glycerine：6%, Sodium Hyaluronate：5%, allantoin：1%, EDETATE SODIUM：
0.6%, Kathon：0.04%, deionized water：Surplus；The summation of above-mentioned each component is 100%；
The American-cockroach-extract uses alcohol precipitation water extraction, by following operation：
A, the full strong adult bombay canary of polypide is selected, is placed in dryer and is toasted with 80 DEG C, is dried to completely dry
After dry, by the use of ethyl alcohol as solvent, 1 is counted according to solid-liquid ratio g/ml:7, it is impregnated 2 months, is mixed with the ethyl alcohol of concentration 95v/v%
Object；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
The Gotu Kola P.E is made by following operation：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
The Noni extract is made by following operation：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:8, by the use of the ethyl alcohol of a concentration of 75v/v% as solvent, pass through
Vacuum distillation obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract.
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, obtains mixed material
A when being down to 40 DEG C at a temperature of material A to be mixed, adds in glycerine and Sodium Hyaluronate, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
Anti-acne repairs efficacy test
Selecting 200 all ages and classes stages from 15 years old, 20 years old, 25 years old, 30 years old, 35 years old respectively from population has whelk
Men and women be randomly divided into treatment group and control group, treatment group 100, control group 100：Its two groups of genders, severity extent is through system
Meter learns processing, and there was no significant difference（P>0.05）.
Therapy, treatment group try out beautiful Lian Pimple removing screams, and 100 patients try out 7 days, are smeared for one day 3-4 times, right
According to group common Pimple removing scream on the market on probation, 100 patients try out 7 days, are smeared for one day 3-4 times.
Note：Criterion of therapeutical effect：Skin lesion subside more than 95% for recovery from illness, skin lesion subside more than 60% be it is effective, skin lesion subside 30% with
It is above effective, less than 30% skin lesion recession is invalid, and treatment cycle is one week.
Result of the test：
Claims (5)
1. the Pimple removing scream of a kind of ingredient containing American cockroach, it is characterised in that include the raw material of following masses percentage：
American-cockroach-extract：2-10%, Gotu Kola P.E：1-10%, Noni extract：1-10%, olive essential oil：0.1-
1%, vitamin E：1-6%, medical ventolin：5-20%, glycerol stearate：2.5-4.5%, glycerine：2-6%, Sodium Hyaluronate：
0.5-5%, allantoin：0.2-1%, EDETATE SODIUM：0.1-1%, Kathon：0-0.04%, deionized water：Surplus；Above-mentioned each component
Summation is 100%.
2. the preparation method of the Pimple removing scream of a kind of ingredient containing American cockroach, it is characterised in that pass through following each step：
（1）By the material preparation of following mass percent：
American-cockroach-extract：2-10%, Gotu Kola P.E：1-10%, Noni extract：1-10%, olive essential oil：0.1-
1%, vitamin E：1-6%, medical ventolin：5-20%, glycerol stearate：2.5-4.5%, glycerine：2-6%, Sodium Hyaluronate：
0.5-5%, allantoin：0.2-1%, EDETATE SODIUM：0.1-1%, Kathon：0-0.04%, deionized water：Surplus；Above-mentioned each component
Summation is 100%；
（2）Medical ventolin is placed in stearin on water-bath and is heated to 80 DEG C and mixes, mixed material A is obtained, treats
When 40 DEG C are down at a temperature of mixed material A, glycerine and Sodium Hyaluronate are added in, obtains mixed material B；
（3）Again at 40 DEG C, allantoin, EDETATE SODIUM and Kathon are added in, stirs evenly, obtains mixed material C；
（4）American-cockroach-extract, Gotu Kola P.E, Noni extract, olive essential oil and dimension are added in mixed material C
Raw element E, stirs evenly, and adds in deionized water, adjusts pH value to 5-6 to get the Pimple removing scream of the ingredient containing American cockroach.
3. preparation method according to claim 2, it is characterised in that：The American-cockroach-extract is carried using alcohol precipitation water
Method, by following operation：
A, the full strong adult bombay canary of polypide is selected, is toasted, is dried to after being completely dried with 70-80 DEG C, use second
Alcohol counts 1 as solvent according to solid-liquid ratio g/ml:（7-9）, impregnated 2 months with the ethyl alcohol of concentration 95v/v%, obtain mixture；
B, mixture is filtered, medicinal extract is concentrated under reduced pressure into gained alcohol extract, and gained medicinal extract is stood, after being layered, with double steamings
Lower floor's object is dissolved, then be concentrated under reduced pressure as solvent, obtains water-soluble medicinal extract, i.e. American-cockroach-extract by water.
4. preparation method according to claim 2, it is characterised in that：The Gotu Kola P.E is made by following operation
：
The centella ethyl alcohol of a concentration of 95v/v% is impregnated for 24 hours, through vacuum distillation, obtains centella alcohol extract and residue, product
The careless alcohol extract of snow obtains extracting solution through ultrasonic extraction 2h, and the ethyl alcohol that a concentration of 75v/v% of 8 times of volumes is added in residue carries out
Ultrasonic wave extraction 2h merges extracting solution through being concentrated under reduced pressure into medicinal extract shape to get Gotu Kola P.E.
5. preparation method according to claim 2, it is characterised in that：The Noni extract is made by following operation
：
It will be crushed, then by solid-liquid ratio 1 after dry Noni fruit baking 6h:（6-10）, by the use of the ethyl alcohol of a concentration of 75v/v% as molten
Agent obtains Noni fruit alcohol extract, then through being concentrated under reduced pressure to get Noni extract through vacuum distillation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810150897.4A CN108158938A (en) | 2018-02-13 | 2018-02-13 | A kind of Pimple removing scream of the ingredient containing American cockroach and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810150897.4A CN108158938A (en) | 2018-02-13 | 2018-02-13 | A kind of Pimple removing scream of the ingredient containing American cockroach and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108158938A true CN108158938A (en) | 2018-06-15 |
Family
ID=62514134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810150897.4A Pending CN108158938A (en) | 2018-02-13 | 2018-02-13 | A kind of Pimple removing scream of the ingredient containing American cockroach and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108158938A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186826A (en) * | 2018-02-13 | 2018-06-22 | 云南诺漫斯生物科技有限公司 | A kind of anti-acne ointment of the ingredient containing American cockroach and preparation method thereof |
| CN110063925A (en) * | 2019-03-19 | 2019-07-30 | 广东医科大学 | A kind of acne-removing composition and preparation method thereof |
| CN115715754A (en) * | 2022-11-29 | 2023-02-28 | 昆明医科大学 | Gel with acne removing and repairing effects and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105434310A (en) * | 2015-12-22 | 2016-03-30 | 广州市娇兰化妆品有限公司 | Application of periplaneta americana active ingredient extract in cosmetic preparation |
| CN106699849A (en) * | 2015-11-11 | 2017-05-24 | 暨南大学 | Novel polypeptide and Periplaneta americana total polypeptide extract capable of promoting tissue repair, and application thereof |
| CN107095810A (en) * | 2017-04-18 | 2017-08-29 | 孙广军 | Centella Pimple removing scream |
-
2018
- 2018-02-13 CN CN201810150897.4A patent/CN108158938A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106699849A (en) * | 2015-11-11 | 2017-05-24 | 暨南大学 | Novel polypeptide and Periplaneta americana total polypeptide extract capable of promoting tissue repair, and application thereof |
| CN105434310A (en) * | 2015-12-22 | 2016-03-30 | 广州市娇兰化妆品有限公司 | Application of periplaneta americana active ingredient extract in cosmetic preparation |
| CN107095810A (en) * | 2017-04-18 | 2017-08-29 | 孙广军 | Centella Pimple removing scream |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186826A (en) * | 2018-02-13 | 2018-06-22 | 云南诺漫斯生物科技有限公司 | A kind of anti-acne ointment of the ingredient containing American cockroach and preparation method thereof |
| CN110063925A (en) * | 2019-03-19 | 2019-07-30 | 广东医科大学 | A kind of acne-removing composition and preparation method thereof |
| CN115715754A (en) * | 2022-11-29 | 2023-02-28 | 昆明医科大学 | Gel with acne removing and repairing effects and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105616283B (en) | A kind of plant essence restorative facial cream | |
| KR101425031B1 (en) | Cosmetic composition for anti-irritation and skin moisturization containing Citrus junos Siebold seed oil and Mangifera Indica seed oil | |
| CN108938513B (en) | Skin-cleaning acne-removing beauty cream and preparation method thereof | |
| CN104027281A (en) | Acne removing cosmetic composition and preparation method thereof | |
| CN111450024A (en) | Essence cream | |
| CN108158938A (en) | A kind of Pimple removing scream of the ingredient containing American cockroach and preparation method thereof | |
| CN108938501A (en) | Chinese medicine composition and oral care product applied to oral care product | |
| CN105943435A (en) | Sebum-balancing anti-acne cosmetic product containing Auricularia auricula extract and preparation method thereof | |
| CN110652483A (en) | Tea tree essential oil acne-removing cream | |
| CN107320363A (en) | A kind of anti-acne essence | |
| KR101274811B1 (en) | Potent anti-acne composition containing perilla frutescens and/or lygodium japonicum extract | |
| CN114681378A (en) | Blackhead-derived cosmetic composition and preparation method thereof | |
| CN112315883B (en) | Skin care composition for controlling oil and removing acne and preparation and application thereof | |
| CN112891271A (en) | Composition for sensitive muscle barrier repair and application of composition in skin care product | |
| KR101418366B1 (en) | Composition containing bee venom and propolis for preventing or treating acne | |
| CN112402308A (en) | Multi-effect relieving moisturizing lotion and preparation method thereof | |
| KR102272771B1 (en) | Cosmetic composition for alleviating sebum secretion comprising Carthamus tinctorius extract or mixture extract of Carthamus tinctorius and Areca catechu | |
| CN103385838A (en) | Anti-freckle whitening emulsion | |
| KR20080111249A (en) | A cosmetic composing chia seed extract | |
| CN105031083A (en) | Application of traditional Chinese medicine composition in oral care products | |
| KR102221627B1 (en) | Composition comprising Rhus Semialata extract as active ingredient | |
| KR102247589B1 (en) | Cosmetic composition for improving skin comprising the moluccella laevis extraction and the hololeion maximowiczii Kitam. extraction as an effective ingredient | |
| CN114306107B (en) | Functional skin product and preparation method thereof | |
| KR102071600B1 (en) | Cream composition manufacturing method for preventing of sensitive-skin and skin-trouble | |
| CN113499271A (en) | Anti-allergy compound and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180712 Address after: 650000 Yunnan Kunming Guandu District Ding Jie Xing Du business center 1 building 27 level 2704. Applicant after: Yunnan Ningkang Biological Technology Co., Ltd. Address before: 650000 Yunnan Kunming Guandu District Xiao Banqiao Street office Xiao Banqiao community neighborhood committee Applicant before: Yunnan noo Biological Technology Co., Ltd. |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180615 |