CN110037976A - Moisturizing anti-inflammatory composition and skin care item - Google Patents
Moisturizing anti-inflammatory composition and skin care item Download PDFInfo
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- CN110037976A CN110037976A CN201910481186.XA CN201910481186A CN110037976A CN 110037976 A CN110037976 A CN 110037976A CN 201910481186 A CN201910481186 A CN 201910481186A CN 110037976 A CN110037976 A CN 110037976A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The present invention relates to cosmetic technical fields, in particular to moisturizing anti-inflammatory composition and skin care item.The moisturizing anti-inflammatory composition is by aloe leaf juice, hyaluronic acid, 4D hyaluronic acid, allantoin, trehalose, marine algae extract, glycine betaine, VB3Composition.Each raw material plays synergistic effect in moisturizing anti-inflammatory composition of the present invention, and each component compounding can be obviously improved using rear skin barrier function, reduces moisture of skin and scatters and disappears, has effects that excellent water lock.Anti-inflammatory efficacy can be improved in moisturizing anti-inflammatory composition compounding of the present invention.The moisturizing anti-inflammatory stoste of inventive formulation not stimulating components such as spirituosity, essence, property is mild, non-stimulated to skin safe, and has good stability.
Description
Technical field
The present invention relates to cosmetic technical fields, in particular to moisturizing anti-inflammatory composition and skin care item.
Background technique
Skin is the maximum organ of human body, not only acts as effect or the personal health looks standard of beauty of protection skin,
Especially face skin not only influences skin appearance when skin water shortage, drying, but also also results in the subjective appearance of consumer
Discomfort, and be possible to cause certain dermopathic deteriorations, lead to the aging in advance of skin.It hydration status in skin and dissipates
Mistake degree is soft and moist and elastic directly related with skin, keeps the wet degree of skin that skin elasticity can be enhanced, makes skin generation
Thank to normal, the generation of reduction wrinkle and color spot.Moisture-keeping efficacy is the most basic function of skin protection cosmetics, how to improve cosmetics
Moisture-keeping efficacy is all of great significance to the research and development of cosmetics and clinical medicine application.
Traditional moisturizer includes glycerol, sorbierite, sodium lactate, propylene glycol and amino acid etc. in cosmetics.These moisturizings
Water absorbability, safety and the stability of agent limit its practical application effect, although such as glycerol, sorbierite and propylene glycol
There is good water retention property, the stickiness of skin care item is but easy to cause to enhance, skin sense decline；Sodium lactate has preferable water conservation energy
Power, but be difficult to emulsify in the formula of product；Hyaluronic acid, collagen, poly-aspartate or amino-acid ester have good water conservation energy
Power, but it is lower the effect of reduction water is evaporated from skin, and can show viscosity in skin surface；It is protected although saualane has
Moist and avoidable water is evaporated from skin surface, but its oiliness property user feels skin greasing.
Based on above-mentioned the shortcomings of the prior art, need to research and develop that a kind of mild, safety, preparation process are simple while having
There are the skin nursing products of good moisture retention energy.
Summary of the invention
In view of this, the present invention provides moisturizing anti-inflammatory composition and skin care item.The moisturizing anti-inflammatory composition has good
Moisturizing, anti-inflammatory effect, property is mild, non-stimulated to skin safe.
In order to achieve the above-mentioned object of the invention, the present invention the following technical schemes are provided:
The present invention provides a kind of moisturizing anti-inflammatory composition, by aloe leaf juice, hyaluronic acid, 4D hyaluronic acid, allantoin,
Trehalose, marine algae extract, glycine betaine, VB3Composition.
Preferably, in parts by weight, the dosage of each raw material are as follows:
60~80 parts of aloe leaf juice, 3~8 parts of hyaluronic acid, 5~10 parts of 4D hyaluronic acid, 0.1~0.2 part of allantoin, sea
2~4 parts of algae sugar, 2~5 parts of marine algae extract, 3~5 parts of glycine betaine, VB32~3 parts.
Preferably, in parts by weight, the dosage of each raw material are as follows:
60 parts of aloe leaf juice, 3 parts of hyaluronic acid, 5 parts of 4D hyaluronic acid, 0.1 part of allantoin, 2 parts of trehalose, seaweed are extracted
2 parts of object, 3 parts of glycine betaine, VB32 parts.
Preferably, in parts by weight, the dosage of each raw material are as follows:
70 parts of aloe leaf juice, 5 parts of hyaluronic acid, 7 parts of 4D hyaluronic acid, 0.15 part of allantoin, 3 parts of trehalose, seaweed mention
Take 3 parts of object, 4 parts of glycine betaine, VB32 parts.
It is highly preferred that in parts by weight, the dosage of each raw material are as follows:
80 parts of aloe leaf juice, 8 parts of hyaluronic acid, 10 parts of 4D hyaluronic acid, 0.2 part of allantoin, 4 parts of trehalose, seaweed mention
Take 5 parts of object, 5 parts of glycine betaine, VB33 parts.
Preferably, glycine betaine is natural glycine betaine.
The present invention also provides can on a kind of skin care item, including moisturizing anti-inflammatory composition provided by the invention and cosmeceutical
The auxiliary material of receiving.
Preferably, mass percentage of the moisturizing anti-inflammatory composition in skin care item is 75%~90%.
Preferably, acceptable auxiliary material is selected from solvent, solubilizer, preservative, antioxidant, pH adjusting on cosmeceutical
Agent, penetrating agent, liposome, moisturizer, thickener, chelating agent, skin sense regulator, surfactant, emulsifier, essence, pigment.
Preferably, skin care item further include other functional additives.
Preferably, in parts by weight, the supplementary material of skin care item includes:
80~100 parts of moisturizing anti-inflammatory composition, 1~10 part of Gotu Kola P.E, bacillus/fermented soybean product extracts
1~10 part of object, 0.1~5 part of ammonium acryloyl taurate/VP copolymer, 0.1~5 part of plant antiseptic agent.
In embodiment provided by the invention, in parts by weight, the supplementary material of skin care item includes:
90 parts of moisturizing anti-inflammatory composition, 4 parts of Gotu Kola P.E, bacillus/3.5 parts of fermented soybean product extract,
1.5 parts of ammonium acryloyl taurate/VP copolymer, 1 part of plant antiseptic agent.
Above-mentioned skin care item the preparation method comprises the following steps: moisturizing anti-inflammatory composition is heated to 75~80 DEG C, stir evenly, then plus
Enter ammonium acryloyl taurate/VP copolymer, be cooled to 35~40 DEG C after mixing evenly, Gotu Kola P.E, bud is added
Spore bacillus/fermented soybean product extract and plant antiseptic agent, are uniformly mixed.
The present invention provides moisturizing anti-inflammatory composition and skin care item.The moisturizing anti-inflammatory composition is by aloe leaf juice, hyalomitome
Acid, 4D hyaluronic acid, allantoin, trehalose, marine algae extract, glycine betaine, VB3Composition.The technical effect that the present invention has are as follows:
Each raw material plays synergistic effect in moisturizing anti-inflammatory composition of the present invention, and each component compounding can be obviously improved
Using rear skin barrier function, reduces moisture of skin and scatter and disappear, have effects that excellent water lock.
Anti-inflammatory efficacy can be improved in moisturizing anti-inflammatory composition compounding of the present invention.
The moisturizing anti-inflammatory composition of the invention known in human body in-service evaluation has good moisturizing, antiinflammation, right
The maintenance effect of skin is obvious, can promote the moisturizing and anti-inflammatory of skin, make skin healthier.
The moisturizing anti-inflammatory stoste of inventive formulation not stimulating components such as spirituosity, essence, property is mild, to skin safe
It is non-stimulated, there is preferable moisturizing anti-inflammatory effect, and have good stability.
Specific embodiment
The invention discloses moisturizing anti-inflammatory composition and skin care item, those skilled in the art can use for reference present disclosure, fit
When improvement realization of process parameters.In particular, it should be pointed out that all similar substitutions and modifications are for a person skilled in the art
It is it will be apparent that they are considered as being included in the present invention.Method of the invention and application passed through preferred embodiment into
Description is gone, related personnel can obviously not depart from the content of present invention, carried out in spirit and scope to methods herein and application
Change or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
Aloe leaf juice: ecological water, bioactive water from aloe, have the characteristics that it is following: containing trace mineral member
Plain such as calcium and magnesium potassium microelement；Ionic strength is low, influences on formulation stability small；And contain micro aloe characteristic component acetyl
Change polysaccharide, there is good moisturizing and repair function.The present invention is using vegetation water --- aloe leaf juice, active constituent content reach
To 99.95%, there is enough moisture, be not required to additional addition deionized water in formula.And the molecule of aloe leaf juice is small,
More easily enter body, make to possess adequate water in skin cell, and bring more active matters into, there is high osmosis；Simultaneously also
Containing aloe-emodin, having makes skin contraction, softness, moisturizing, anti-inflammatory and releases the works such as hardening, angling, improvement scar
With；It is also rich in amino acid and organic acid, polysaccharide, vitamin, enzyme and multi mineral prime element except from this, while there is beauty
White, crease-resistant, cell repair improves the effects of immunity.
4D hyaluronic acid is mainly by Sodium Hyaluronate (macromolecular), oligomerization Sodium Hyaluronate (small molecule), hyaluronic acid
Elastomer (reticular structure), acetylation Sodium Hyaluronate (lipophilicity) composition.The present invention utilizes the synergistic effect of 4D hyaluronic acid,
Water lock net is formed in skin surface, moisture is lockked into each cortex in skin, carries out moisturizing layer by layer from inside to outside；It can be rapidly
Cuticula is permeated, can be directly entered inside skin and supplement cell moisture, increases cell water content, institute is necessary daily for supplement skin
Moisture, fundamentally solve the problems, such as dry skin.
Marine algae extract: seaweed is plant most ancient in the world, and unrooted is also had no result without flower.Rich in amino acid, vitamin
And mucopolysaccharide, there are moisturizing, lubrication and wrinkle resistant effect to skin.
Raw materials used or auxiliary material is available on the market in moisturizing anti-inflammatory composition and skin care item provided by the invention.Its
In, aloe leaf juice is purchased from Yunnan Wan Lv company, and hyaluronic acid is purchased from Fu Ruida, allantoin purchased from the prosperous biology of China, 4D hyaluronic acid
Purchased from remittance youth, trehalose is purchased from prestige section, and biology when marine algae extract is purchased from Xi'an benefit, natural glycine betaine is purchased from the macro biological section of exhibition
Skill, VB3Purchased from the Shanghai day rank of nobility.
Below with reference to embodiment, the present invention is further explained:
Embodiment 1
Water-free moisturizing anti-inflammatory composition includes by weight following component:
60 parts of aloe leaf juice, 3 parts of hyaluronic acid, 5 parts of 4D hyaluronic acid, 0.1 part of allantoin, 2 parts of trehalose, seaweed are extracted
2 parts of object, 3 parts of natural glycine betaine, 2 parts of VB3.
Embodiment 2
Water-free moisturizing anti-inflammatory composition includes by weight following component:
70 parts of aloe leaf juice, 5 parts of hyaluronic acid, 7 parts of 4D hyaluronic acid, 0.15 part of allantoin, 3 parts of trehalose, seaweed mention
Take 3 parts of object, 4 parts of natural glycine betaine, 2 parts of VB3.
Embodiment 3
Water-free moisturizing anti-inflammatory composition includes by weight following component:
80 parts of aloe leaf juice, 8 parts of hyaluronic acid, 10 parts of 4D hyaluronic acid, 0.2 part of allantoin, 4 parts of trehalose, seaweed mention
Take 5 parts of object, 5 parts of natural glycine betaine, 3 parts of VB3.
Comparative example 1
Water-free moisturizing anti-inflammatory composition includes by weight following component:
60 parts of aloe leaf juice, 0.1 part of allantoin, 2 parts of trehalose, 2 parts of marine algae extract, 3 parts of natural glycine betaine, VB3 2
Part.
Comparative example 2
Water-free moisturizing anti-inflammatory composition includes by weight following component:
3 parts of hyaluronic acid, 5 parts of 4D hyaluronic acid, 0.1 part of allantoin, 2 parts of trehalose, 2 parts of marine algae extract, crude sweet
3 parts of dish alkali, VB32 parts.
Comparative example 3
Water-free moisturizing anti-inflammatory composition includes by weight following component:
5 parts of aloe leaf juice, 3 parts of hyaluronic acid, 5 parts of 4D hyaluronic acid, 0.1 part of allantoin, 3 parts of natural glycine betaine, VB3 2
Part.
Comparative example 4
Water-free moisturizing anti-inflammatory composition includes by weight following component:
20 parts of aloe leaf juice, 20 parts of hyaluronic acid, 15 parts of 4D hyaluronic acid, 0.5 part of allantoin, 1 part of trehalose, seaweed mention
Take 0.5 part of object, 8 parts of natural glycine betaine, VB31.5 part.
Comparative example 5
Water-free moisturizing anti-inflammatory composition includes by weight following component:
150 parts of aloe leaf juice, 20 parts of hyaluronic acid, 15 parts of 4D hyaluronic acid, 0.1 part of allantoin, 15 parts of trehalose, seaweed
15 parts of extract, 10 parts of natural glycine betaine, VB38 parts.
Embodiment 4, moisture-keeping efficacy verifying
With comparative example 1-5 1-5 as a control group, aloe extract obtained as a comparison case 6 is extracted with conventional method, with reality
The moisturizing anti-inflammatory composition in example 1,2,3 is applied as experimental group 1-3, compares the moisture content value (MMV) before and after the effect of the two
It is worth (TEWL) with scattering and disappearing through transepidermal water.
Human trial evaluation moisture-keeping efficacy is the highest moistening effect evaluation method of more common and generally acknowledged degree.Therefore, this reality
It applies example and moisture-keeping efficacy is evaluated using human trial.Specific test process is as follows:
1) 30 people of subject is selected, at the left and right inboard arm of subject is away from palm base portion 5cm, defines 2 in left forearm
The identical region of area (4cm × 4cm) is used as using area；The point of right forearm same position is left and right as blank control region
The corresponding region of arm is tested simultaneously.
2) subject circuits sequentially smearing aloe extract, other comparative example products in two test areas of arm and contains
There is the moisturizing anti-inflammatory composition embodiment 1-3 of Chinese aloe leaf juice.1 after smearing, 2,4,6,8h, moisture of skin measuring instrument is used
CorneometerCM825 (German CourageKhazaka company) tests the hydration status of skin, is surveyed using percutaneous moisture loss
The water loss amount for measuring instrument TewameterTM300 (German Courage Khazaka company) test skin, measures 5 times, makes even
Mean value.
2.1 skin hydration state verifications
Moisture content change was reacted within test period, and actual area moisture content changes over time rule.Its value is bigger,
Moisture content is bigger, conversely, moisture content is smaller.
Subject's test position moisture content changes over time as shown in table 1.
1 skin hydration state verification result of table
2.2 moisture loss situations
Moisture of skin windage (TEWL) reflected in test period, and Experimental Area moisture loss changes with time rule
Rule, it can characterize the water lock function of cosmetics.Its value is smaller, and moisture loss is fewer, and water lock ability is stronger；Conversely, water lock energy
Power is weaker.Subjects skin's moisture loss test result is shown in Table 2.
2 moisture of skin of table scatters and disappears test result
From skin hydration state verification result and moisture loss result it can be seen that
By embodiment in table 1 it is found that each in the moisturizing anti-inflammatory composition of present invention leaf juice containing aloe compared with comparative example
Component compounding can be obviously improved using rear skin hydration state, have apparent moistening effect.By embodiment and comparative example in table 2
Comparison it is found that each component compounding can be obviously improved using rear skin screen in the moisturizing anti-inflammatory composition of present invention leaf juice containing aloe
Hinder function, reduces moisture of skin and scatter and disappear, have effects that excellent water lock.Wherein the effect of embodiment 3 is most preferred embodiment.
Embodiment 5, anti-inflammatory efficacy verifying
With comparative example 1-5 1-5 as a control group, 6 are organized as a comparison with aloe extract made from traditional extraction, to implement
The moisturizing anti-inflammatory composition of the leaf juice containing aloe in example 1,2,3 compares the anti-inflammatory efficacy of the two as experimental group 1-3.Specific mistake
Journey is as follows:
Kunming male mice 50,25 ± 2g of weight is randomly divided into 10 groups.Drug study group, contrast groups are picked with cotton swab
The medical fluid of each 20 μ L is spread evenly across two sides before and after every mouse right ear, and Zuo Eryong physiological saline is coated in the same way, so
20 μ L of about 100% dimethylbenzene is picked with cotton swab afterwards and is evenly and rapidly coated on every mouse right ear front and back two sides, is recorded every small
Mouse coating and sensitization time, and 0.5,1.5,2.5h repeated drug taking after causing inflammation, left ear same amount of normal saline concurrent control.
It causes 4h after inflammation to put to death animal, cuts two ears along auricle base line, two ears are laid into auricle weighing with 6mm diameter trepan device, are used in combination
Micrometer caliper measures the thickness of bilateral auricle, and the difference of every two auricle weight of mouse is swelling, the thickness difference of bilateral auricle
For thickness difference.
3 mouse corrosion disease efficacy test result of table
Obviously compare comparative example from the mouse ear thickness difference and swelling that can be seen that in embodiment 1-3 in experimental result
It is small with physiological saline group, illustrate that anti-inflammatory efficacy can be improved in anti-inflammatory composition compounding, wherein the antiphlogistic effects of embodiment 3 are
Most preferred embodiment.
Embodiment 6, application
Composition of the invention can be mixed with the skin care of various dosage forms with the acceptable auxiliary material in skin protection cosmetics field
Cosmetics；Wherein, the composition accounts for the 75%~90% of skin protection cosmetics gross weight.The acceptable auxiliary material choosing in skin protection cosmetics field
From: solvent, solubilizer, preservative, antioxidant, pH adjusting agent, penetrating agent, liposome, moisturizer, thickener, chelating agent, skin sense
Regulator, surfactant, emulsifier, essence, pigment and other functional additives.
The present embodiment is for preparing moisturizing anti-inflammatory stoste comprising each component of following weight percent content: implements
The moisturizing anti-inflammatory composition 90% of example 3, Gotu Kola P.E 4%, bacillus/fermented soybean product extract 3.5%, propylene
Acyl dimethyltaurine ammonium/VP copolymer 1 .5%, plant antiseptic agent 1%.
Preparation method are as follows:
Each substance in moisturizing anti-inflammatory composition is heated to 75~80 DEG C, is stirred evenly, acryloyl diformazan is then added
Base taurine ammonium/VP copolymer is cooled to 35-40 DEG C after mixing evenly, and Gotu Kola P.E, bacillus/soybean hair is added
Ferment product extract and plant antiseptic agent, are uniformly mixed, and are down to room temperature, and inspection material takes the dish out of the pot.
One, cutaneous safety assessment is carried out to moisturizing anti-inflammatory stoste obtained
30 personnel for participating in test, 15 males, 15 women, average age 31 are selected by subject enrollment standard
Year.Tested material is put into spot tester, dosage is about 0.020g~0.025g.Control wells are that blank control (does not place any object
Matter), the back of subject will be covered on non-stimulated adhesive tape added with the spot tester of tested material, be gently pressed with palm and be allowed to uniformly paste
It is overlying on skin, continues for 24 hours.30min after removal spot tester observes dermoreaction after impression disappearance, by skin adverse reaction
Grade scale table divides adverse reaction grade.If result is feminine gender, observed again respectively with 48h for 24 hours after patch test primary.
Human skin patch test result is shown: the patch test of the embodiment 6 of 30 subjects through the invention,
0.5,24,48h observation dermoreaction illustrate that moisturizing anti-inflammatory stoste of the invention is safety wherein 0 skin adverse reaction occurs
's.
Two, stability test
4 estimation of stability of table
From stability experiment as can be seen that water-free stoste is after stability test made of moisturizing anti-inflammatory composition
Qualification illustrates that the moisturizing anti-inflammatory stoste has good stability.
Three, in order to measure effect of the composition in cosmetics, following normal individual trial evaluation has been done
Test product: the moisturizing anti-inflammatory stoste obtained by embodiment 3
Test object: 30 volunteers of selection, the age 18~25 years old
Test method: it is required that volunteer on probation uses the moisturizing anti-inflammatory stoste as made from embodiment 3 daily, continuous use
One month, the return visit of product effect was done at the 30th day, and keep a record.As a result such as the following table 5.
5 volunteer's using effect of table
Moisturizing anti-inflammatory stoste of the invention has good moisturizing, antiinflammation known in human body in-service evaluation, to flesh
The maintenance effect of skin is obvious, can promote the moisturizing and anti-inflammatory of skin, make skin healthier.
The above is only the preferred embodiment of the present invention, it is noted that those skilled in the art are come
It says, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications also should be regarded as
Protection scope of the present invention.
Claims (10)
1. a kind of moisturizing anti-inflammatory composition, which is characterized in that by aloe leaf juice, hyaluronic acid, 4D hyaluronic acid, allantoin, sea
Algae sugar, marine algae extract, glycine betaine, VB3Composition.
2. moisturizing anti-inflammatory composition according to claim 1, which is characterized in that in parts by weight, the dosage of each raw material are as follows:
60~80 parts of aloe leaf juice, 3~8 parts of hyaluronic acid, 5~10 parts of 4D hyaluronic acid, 0.1~0.2 part of allantoin, trehalose
2~4 parts, 2~5 parts of marine algae extract, 3~5 parts of glycine betaine, VB32~3 parts.
3. moisturizing anti-inflammatory composition according to claim 1, which is characterized in that in parts by weight, the dosage of each raw material are as follows:
60 parts of aloe leaf juice, 3 parts of hyaluronic acid, 5 parts of 4D hyaluronic acid, 0.1 part of allantoin, 2 parts of trehalose, marine algae extract 2
Part, 3 parts of glycine betaine, VB32 parts.
4. moisturizing anti-inflammatory composition according to claim 1, which is characterized in that in parts by weight, the dosage of each raw material are as follows:
70 parts of aloe leaf juice, 5 parts of hyaluronic acid, 7 parts of 4D hyaluronic acid, 0.15 part of allantoin, 3 parts of trehalose, marine algae extract 3
Part, 4 parts of glycine betaine, VB32 parts.
5. moisturizing anti-inflammatory composition according to any one of claim 1 to 4, which is characterized in that in parts by weight, each original
The dosage of material are as follows:
80 parts of aloe leaf juice, 8 parts of hyaluronic acid, 10 parts of 4D hyaluronic acid, 0.2 part of allantoin, 4 parts of trehalose, marine algae extract 5
Part, 5 parts of glycine betaine, VB33 parts.
6. a kind of skin care item, which is characterized in that including moisturizing anti-inflammatory composition and makeup described in any one of claims 1 to 5
Acceptable auxiliary material in conduct and learning.
7. skin care item according to claim 6, which is characterized in that quality of the moisturizing anti-inflammatory composition in skin care item
Percentage composition is 75%~90%.
8. skin care item according to claim 6, which is characterized in that acceptable auxiliary material is selected from molten on the cosmeceutical
Agent, solubilizer, preservative, antioxidant, pH adjusting agent, penetrating agent, liposome, moisturizer, thickener, chelating agent, skin sense are adjusted
Agent, surfactant, emulsifier, essence, pigment.
9. skin care item according to claim 8, which is characterized in that the skin care item further include other functional additives.
10. skin care item according to any one of claims 6 to 9, which is characterized in that in parts by weight, the skin care item
Supplementary material include:
80~100 parts of moisturizing anti-inflammatory composition, 1~10 part of Gotu Kola P.E, bacillus/fermented soybean product extract 1
~10 parts, 0.1~5 part of ammonium acryloyl taurate/VP copolymer, 0.1~5 part of plant antiseptic agent.
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| CN201910481186.XA CN110037976B (en) | 2019-06-04 | 2019-06-04 | Moisturizing and anti-inflammatory composition and skin care product |
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| CN201910481186.XA CN110037976B (en) | 2019-06-04 | 2019-06-04 | Moisturizing and anti-inflammatory composition and skin care product |
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| CN110037976A true CN110037976A (en) | 2019-07-23 |
| CN110037976B CN110037976B (en) | 2022-08-09 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112022895A (en) * | 2020-09-18 | 2020-12-04 | 山东华熙海御生物医药有限公司 | Composition for skin barrier repair and preparation method thereof |
| CN114425032A (en) * | 2021-12-23 | 2022-05-03 | 湖南人文科技学院 | Moisturizing and anti-inflammatory composition and preparation method and application thereof |
| CN117797082A (en) * | 2024-03-01 | 2024-04-02 | 广州诗妃生物科技有限公司 | Composition with antipruritic effect and application thereof in preparing repair milk |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106265471A (en) * | 2016-08-22 | 2017-01-04 | 台山美环健芦荟制品有限公司 | A kind of aloetic replenishing water and preserving moisture cosmetic composition and application thereof |
| CN109223670A (en) * | 2018-10-11 | 2019-01-18 | 广州艾蓓生物科技有限公司 | A kind of moisture-keeping composition and deep moisturizing foundation emulsion |
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2019
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106265471A (en) * | 2016-08-22 | 2017-01-04 | 台山美环健芦荟制品有限公司 | A kind of aloetic replenishing water and preserving moisture cosmetic composition and application thereof |
| CN109223670A (en) * | 2018-10-11 | 2019-01-18 | 广州艾蓓生物科技有限公司 | A kind of moisture-keeping composition and deep moisturizing foundation emulsion |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112022895A (en) * | 2020-09-18 | 2020-12-04 | 山东华熙海御生物医药有限公司 | Composition for skin barrier repair and preparation method thereof |
| CN114425032A (en) * | 2021-12-23 | 2022-05-03 | 湖南人文科技学院 | Moisturizing and anti-inflammatory composition and preparation method and application thereof |
| CN114425032B (en) * | 2021-12-23 | 2023-05-12 | 湖南人文科技学院 | Moisturizing and anti-inflammatory composition and preparation method and application thereof |
| CN117797082A (en) * | 2024-03-01 | 2024-04-02 | 广州诗妃生物科技有限公司 | Composition with antipruritic effect and application thereof in preparing repair milk |
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| Publication number | Publication date |
|---|---|
| CN110037976B (en) | 2022-08-09 |
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