CN109996533A - 用于肠胃外施用他喷他多的稳定制剂 - Google Patents

用于肠胃外施用他喷他多的稳定制剂 Download PDF

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Publication number
CN109996533A
CN109996533A CN201780058585.4A CN201780058585A CN109996533A CN 109996533 A CN109996533 A CN 109996533A CN 201780058585 A CN201780058585 A CN 201780058585A CN 109996533 A CN109996533 A CN 109996533A
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CN
China
Prior art keywords
composition
weight
total
conjugate
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201780058585.4A
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English (en)
Chinese (zh)
Inventor
A.埃勒曼
U.赖因霍尔德
U.贝尔特拉姆
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Gruenenthal GmbH
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Gruenenthal GmbH
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56997349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN109996533(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of CN109996533A publication Critical patent/CN109996533A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201780058585.4A 2016-09-23 2017-09-22 用于肠胃外施用他喷他多的稳定制剂 Pending CN109996533A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16190255.6 2016-09-23
EP16190255 2016-09-23
PCT/EP2017/073983 WO2018055070A1 (en) 2016-09-23 2017-09-22 Stable formulation for parenteral administration of tapentadol

Publications (1)

Publication Number Publication Date
CN109996533A true CN109996533A (zh) 2019-07-09

Family

ID=56997349

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780058585.4A Pending CN109996533A (zh) 2016-09-23 2017-09-22 用于肠胃外施用他喷他多的稳定制剂

Country Status (17)

Country Link
US (1) US10898452B2 (enExample)
EP (1) EP3515412B1 (enExample)
JP (1) JP7160799B2 (enExample)
KR (1) KR20190057349A (enExample)
CN (1) CN109996533A (enExample)
AU (1) AU2017329964B2 (enExample)
BR (1) BR112019005439A2 (enExample)
CA (1) CA3037810A1 (enExample)
CL (1) CL2019000690A1 (enExample)
CO (1) CO2019002557A2 (enExample)
EA (1) EA201990744A1 (enExample)
EC (1) ECSP19019253A (enExample)
ES (1) ES3027562T3 (enExample)
IL (1) IL265477A (enExample)
MX (1) MX2019003257A (enExample)
PE (1) PE20190908A1 (enExample)
WO (1) WO2018055070A1 (enExample)

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CN103501775A (zh) * 2011-03-04 2014-01-08 格吕伦塔尔有限公司 他喷他多的胃肠外给药
CN103501773A (zh) * 2011-03-04 2014-01-08 格吕伦塔尔有限公司 用于口服给予的他喷他多含水药物制剂
CN103501774A (zh) * 2011-03-04 2014-01-08 格吕伦塔尔有限公司 含有他喷他多的半固体含水药用组合物
CN103735500A (zh) * 2014-01-28 2014-04-23 江苏华泽医药科技有限公司 盐酸他喷他多注射液及其制备方法
WO2014068372A1 (en) * 2012-11-01 2014-05-08 Torrent Pharmaceuticals Ltd Pharmaceutical composition of tapentadol for parenteral administration

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Also Published As

Publication number Publication date
EP3515412A1 (en) 2019-07-31
CA3037810A1 (en) 2018-03-29
US20180085328A1 (en) 2018-03-29
ES3027562T3 (en) 2025-06-16
JP7160799B2 (ja) 2022-10-25
PE20190908A1 (es) 2019-06-26
BR112019005439A2 (pt) 2019-06-18
AU2017329964A1 (en) 2019-03-14
US10898452B2 (en) 2021-01-26
AU2017329964B2 (en) 2022-10-06
EP3515412B1 (en) 2025-04-23
ECSP19019253A (es) 2019-03-29
CO2019002557A2 (es) 2019-05-10
IL265477A (en) 2019-05-30
EP3515412C0 (en) 2025-04-23
CL2019000690A1 (es) 2019-06-14
MX2019003257A (es) 2019-06-10
JP2019529442A (ja) 2019-10-17
KR20190057349A (ko) 2019-05-28
EA201990744A1 (ru) 2019-08-30
WO2018055070A1 (en) 2018-03-29

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