JP7160799B2 - タペンタドールの非経口投与用安定製剤 - Google Patents

タペンタドールの非経口投与用安定製剤 Download PDF

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JP7160799B2
JP7160799B2 JP2019515433A JP2019515433A JP7160799B2 JP 7160799 B2 JP7160799 B2 JP 7160799B2 JP 2019515433 A JP2019515433 A JP 2019515433A JP 2019515433 A JP2019515433 A JP 2019515433A JP 7160799 B2 JP7160799 B2 JP 7160799B2
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mmol
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tapentadol
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JP2019529442A5 (enExample
JP2019529442A (ja
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エラーマン・アンゲーリカ
ラインホルト・ウルリヒ
ベルトラム・ウルリケ
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グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2019515433A 2016-09-23 2017-09-22 タペンタドールの非経口投与用安定製剤 Active JP7160799B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16190255.6 2016-09-23
EP16190255 2016-09-23
PCT/EP2017/073983 WO2018055070A1 (en) 2016-09-23 2017-09-22 Stable formulation for parenteral administration of tapentadol

Publications (3)

Publication Number Publication Date
JP2019529442A JP2019529442A (ja) 2019-10-17
JP2019529442A5 JP2019529442A5 (enExample) 2020-10-22
JP7160799B2 true JP7160799B2 (ja) 2022-10-25

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ID=56997349

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JP2019515433A Active JP7160799B2 (ja) 2016-09-23 2017-09-22 タペンタドールの非経口投与用安定製剤

Country Status (17)

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US (1) US10898452B2 (enExample)
EP (1) EP3515412B1 (enExample)
JP (1) JP7160799B2 (enExample)
KR (1) KR20190057349A (enExample)
CN (1) CN109996533A (enExample)
AU (1) AU2017329964B2 (enExample)
BR (1) BR112019005439A2 (enExample)
CA (1) CA3037810A1 (enExample)
CL (1) CL2019000690A1 (enExample)
CO (1) CO2019002557A2 (enExample)
EA (1) EA201990744A1 (enExample)
EC (1) ECSP19019253A (enExample)
ES (1) ES3027562T3 (enExample)
IL (1) IL265477A (enExample)
MX (1) MX2019003257A (enExample)
PE (1) PE20190908A1 (enExample)
WO (1) WO2018055070A1 (enExample)

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JP2014506899A (ja) 2011-03-04 2014-03-20 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 経口投与用タペンタドールの水性医薬製剤
CN103735500A (zh) 2014-01-28 2014-04-23 江苏华泽医药科技有限公司 盐酸他喷他多注射液及其制备方法
JP2014510067A (ja) 2011-03-04 2014-04-24 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング タペンタドールの非経口的投与
JP2015535274A (ja) 2012-11-01 2015-12-10 トレント・ファーマシューティカルズ・リミテッドＴｏｒｒｅｎｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｉｍｉｔｅｄ 非経口投与のためのタペンタドールの薬学的組成物
JP2016512210A (ja) 2013-03-14 2016-04-25 ベクトン ディッキンソン フランス エス．エー．エス． 注射可能なモルヒネ製剤

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JP2014506900A (ja) 2011-03-04 2014-03-20 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング タペンタドールを含む半固形の水性医薬組成物
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EP3515412A1 (en) 2019-07-31
CA3037810A1 (en) 2018-03-29
US20180085328A1 (en) 2018-03-29
ES3027562T3 (en) 2025-06-16
PE20190908A1 (es) 2019-06-26
BR112019005439A2 (pt) 2019-06-18
AU2017329964A1 (en) 2019-03-14
US10898452B2 (en) 2021-01-26
CN109996533A (zh) 2019-07-09
AU2017329964B2 (en) 2022-10-06
EP3515412B1 (en) 2025-04-23
ECSP19019253A (es) 2019-03-29
CO2019002557A2 (es) 2019-05-10
IL265477A (en) 2019-05-30
EP3515412C0 (en) 2025-04-23
CL2019000690A1 (es) 2019-06-14
MX2019003257A (es) 2019-06-10
JP2019529442A (ja) 2019-10-17
KR20190057349A (ko) 2019-05-28
EA201990744A1 (ru) 2019-08-30
WO2018055070A1 (en) 2018-03-29

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