CN109925448A - A kind of Chinese medicine composition for treating pig blue-ear disease - Google Patents
A kind of Chinese medicine composition for treating pig blue-ear disease Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compositions for treating pig blue-ear disease, by following raw material preparation gained: 15~20 parts of Honegsukle flower P.E chlorogenic acid, 10~15 parts of cordate houttuynia, 10~15 parts of Crisped Ardisia Ardisia gigantifolia, 10~15 parts of berberine, 6~10 parts of dandelion, 8~12 parts of campanulaceae, 10~15 parts of origanum oil, 8~12 parts of perilla leaf, 10~20 parts of fucoidin, 3~7 parts of pilose gerbera herb, 4~8 parts of Lentinan, 4~12 parts of tassel flower, 5~10 parts of schizonepeta, 10~15 parts of wilsonii, 3~5 parts of hawthorn, 6~8 parts of reed root, 3~5 parts of Radix Glycyrrhizae, 6~18 parts of astragalus polyose.In side of the invention all medicine phases and, there is clearing heat and detoxicating, anti-inflammation and sterilization, antiviral, spleen benefiting and stimulating the appetite, the effect of improving immunity of organisms, to pig blue-ear disease piglet and Adult Pig have an apparent curative effect, and take for a long time and do not develop drug resistance, noresidue.
Description
Technical field
The present invention relates to herding pharmaceutical arts, and in particular to a kind of Chinese medicine composition for treating pig blue-ear disease.
Background technique
Porcine reproductive and respiratory syndrome, also known as blue otopathy are a kind of pig breathing caused by virus and breeding difficulty
Disease is a kind of worldwide Infectious Diseases of pig breeding industry, mostly occurs in temperature higher summer, autumn, spread speed
Fastly, the course of disease is sustainable 1~2 month in a pig farm.For the disease incidence on most of pig farm up to 50% or more, the death rate can
Up to 20%~50%, serious up to 90%, if hog cholera vaccine is immunized when this disease occurs again, morbidity and mortality can be more
It is high.Pig immunity degradation after occurring due to high-pathogenicity blue ear disease, often secondary Porcine circovirus desease, haemophilus parasuis
Disease, eperythrozoonosis, streptococcosis etc. keep the state of an illness more complicated, treat more difficult.Pig blue-ear disease is mainly shown as height
Heat is delaied, and whole skin is rubescent, and the course of disease slightly long sick pig ear, eyelet and perianal turn blue cyanosis, under abdomen and limb end
Even whole skin occurs rubescent blue.Some appearance eye conjunctivitis, palpebral edema, exophthalmos, individual sick pig astasias,
There are sample nervous symptoms of striking in four limbs.Pregnant sow also occurs miscarriage, produces stillborn foetus phenomenon.It is treated with antibiotic and sulfa drugs
It produces little effect.When cyanosis occurs in skin under ear and abdomen, the death rate is high.
Currently, the method for prevention and treatment pig blue-ear disease is more, mainly prevented and treated using Western medicine, immunoprophylaxis, Chinese herbal medicine etc..
Wherein, what Western medicine used, which spread unchecked, brings great security risk to pork based food, and medicament residue has become influence pork
One of principal element of product safety.Immunoprophylaxis early stage results are preferable, but need repeatedly inoculation, troublesome in poeration, Er Qiecheng
This is higher, be easy to cause stress reaction；And there is dispute in clinical use in vaccine inoculation, and it can not large-scale promotion.Medium-height grass
Medicine treatment is current one of main direction of studying.
Summary of the invention
To solve the above problems, the present invention provides a kind of Chinese medicine composition for treating pig blue-ear disease, in side all medicine phases and,
It is antiviral with clearing heat and detoxicating, anti-inflammation and sterilization, improve immunity of organisms the effect of, to pig blue-ear disease piglet and adult
Pig has apparent curative effect.
To achieve the above object, the technical scheme adopted by the invention is as follows:
A kind of Chinese medicine composition for treating pig blue-ear disease prepares gained by following raw material:
15~20 parts of Honegsukle flower P.E chlorogenic acid, 10~15 parts of cordate houttuynia, 10~15 parts of Crisped Ardisia Ardisia gigantifolia, berberine
10~15 parts, 6~10 parts of dandelion, 8~12 parts of campanulaceae, 10~15 parts of origanum oil, 8~12 parts of perilla leaf, fucoidin 10~
20 parts, 3~7 parts of pilose gerbera herb, 4~8 parts of Lentinan, 4~12 parts of tassel flower, 5~10 parts of schizonepeta, wilsonii 10~15
Part, 3~5 parts of hawthorn, 6~8 parts of reed root, 3~5 parts of Radix Glycyrrhizae, 6~18 parts of astragalus polyose.
Preferably, gained is prepared by following raw material:
15 parts of Honegsukle flower P.E chlorogenic acid, 10 parts of cordate houttuynia, 10 parts of Crisped Ardisia Ardisia gigantifolia, 10 parts of berberine, dandelion 6
Part, 8 parts of campanulaceae, 10 parts of origanum oil, 8 parts of perilla leaf, 10 parts of fucoidin, 3 parts of pilose gerbera herb, 4 parts of Lentinan, tassel flower
4 parts, 5 parts of schizonepeta, 10 parts of wilsonii, 3 parts of hawthorn, 6 parts of reed root, 3 parts of Radix Glycyrrhizae, 6 parts of astragalus polyose.
Preferably, gained is prepared by following raw material:
20 parts of Honegsukle flower P.E chlorogenic acid, 15 parts of cordate houttuynia, 15 parts of Crisped Ardisia Ardisia gigantifolia, 15 parts of berberine, dandelion
10 parts, 12 parts of campanulaceae, 15 parts of origanum oil, 12 parts of perilla leaf, 20 parts of fucoidin, 7 parts of pilose gerbera herb, 8 parts of Lentinan, one
Point red 12 parts, 10 parts of schizonepeta, 15 parts of wilsonii, 5 parts of hawthorn, 8 parts of reed root, 5 parts of Radix Glycyrrhizae, 18 parts of astragalus polyose.
Preferably, gained is prepared by following raw material:
17.5 parts of Honegsukle flower P.E chlorogenic acid, 12.5 parts of cordate houttuynia, 12.5 parts of Crisped Ardisia Ardisia gigantifolia, berberine 12.5
Part, 8 parts of dandelion, 10 parts of campanulaceae, 12.5 parts of origanum oil, 10 parts of perilla leaf, 15 parts of fucoidin, 5 parts of pilose gerbera herb, Lenlinus edodes
6 parts of polysaccharide, 8 parts of tassel flower, 7.5 parts of schizonepeta, 12.5 parts of wilsonii, 4 parts of hawthorn, 7 parts of reed root, 4 parts of Radix Glycyrrhizae, astragalus polyose 12
Part.
Further, the composition is as obtained by following steps preparation:
S1, each component is weighed by weight；
S2, by weighed cordate houttuynia, Crisped Ardisia Ardisia gigantifolia, dandelion, campanulaceae, origanum oil, perilla leaf, pilose gerbera herb, tassel flower,
Schizonepeta, wilsonii, hawthorn, reed root and Radix Glycyrrhizae are cleaned and drain, and are placed in far infrared drying oven after drying, slice/section is placed in ultrasound
In wave wall-breaking machine, supersonic wave wall breaking processing is carried out under conditions of 5~10 DEG C, CO2 gas shield, obtains traditional Chinese medicine powder；
S3, by resulting traditional Chinese medicine powder and weighed Honegsukle flower P.E chlorogenic acid, berberine, fucoidin, mushroom
Granulose, astragalus polyose are mixed evenly to get composition.
Further, in the step S2, the temperature of far-infrared ray drying is 50~70 DEG C, and the time is 3~7h.
The invention has the following advantages:
In side all medicine phases and, there is clearing heat and detoxicating, anti-inflammation and sterilization, antiviral, spleen benefiting and stimulating the appetite improves the function of immunity of organisms
Effect has apparent curative effect to the piglet and Adult Pig that suffer from pig blue-ear disease, and takes for a long time and do not develop drug resistance, without residual
It stays.
Specific embodiment
The present invention is described in detail combined with specific embodiments below.Following embodiment will be helpful to the technology of this field
Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill of this field
For personnel, without departing from the inventive concept of the premise, various modifications and improvements can be made.These belong to the present invention
Protection scope.
Embodiment 1
A kind of Chinese medicine composition for treating pig blue-ear disease, as obtained by following steps preparation:
S1, weigh by weight: 15 parts of Honegsukle flower P.E chlorogenic acid, 10 parts of cordate houttuynia, 10 parts of Crisped Ardisia Ardisia gigantifolia, the coptis are small
10 parts of bark of a cork tree alkali, 6 parts of dandelion, 8 parts of campanulaceae, 10 parts of origanum oil, 8 parts of perilla leaf, 10 parts of fucoidin, 3 parts of pilose gerbera herb, mushroom
4 parts of granulose, 4 parts of tassel flower, 5 parts of schizonepeta, 10 parts of wilsonii, 3 parts of hawthorn, 6 parts of reed root, 3 parts of Radix Glycyrrhizae, 6 parts of astragalus polyose；
S2, by weighed cordate houttuynia, Crisped Ardisia Ardisia gigantifolia, dandelion, campanulaceae, origanum oil, perilla leaf, pilose gerbera herb, tassel flower,
Schizonepeta, wilsonii, hawthorn, reed root and Radix Glycyrrhizae are cleaned and drain, and are placed in far infrared drying oven, 50~70 DEG C of 3~7h of drying process
Afterwards, slice/section is placed in supersonic wave wall breaking machine, is carried out at supersonic wave wall breaking under conditions of 5~10 DEG C, CO2 gas shield
Reason, obtains traditional Chinese medicine powder；
S3, by resulting traditional Chinese medicine powder and weighed Honegsukle flower P.E chlorogenic acid, berberine, fucoidin, mushroom
Granulose, astragalus polyose are mixed evenly to get composition.
Embodiment 2
A kind of Chinese medicine composition for treating pig blue-ear disease, as obtained by following steps preparation:
S1, weigh by weight: 20 parts of Honegsukle flower P.E chlorogenic acid, 15 parts of cordate houttuynia, 15 parts of Crisped Ardisia Ardisia gigantifolia, the coptis are small
15 parts of bark of a cork tree alkali, 10 parts of dandelion, 12 parts of campanulaceae, 15 parts of origanum oil, 12 parts of perilla leaf, 20 parts of fucoidin, 7 parts of pilose gerbera herb,
8 parts of Lentinan, 12 parts of tassel flower, 10 parts of schizonepeta, 15 parts of wilsonii, 5 parts of hawthorn, 8 parts of reed root, 5 parts of Radix Glycyrrhizae, astragalus polyose
18 parts；
S2, by weighed cordate houttuynia, Crisped Ardisia Ardisia gigantifolia, dandelion, campanulaceae, origanum oil, perilla leaf, pilose gerbera herb, tassel flower,
Schizonepeta, wilsonii, hawthorn, reed root and Radix Glycyrrhizae are cleaned and drain, and are placed in far infrared drying oven, 50~70 DEG C of 3~7h of drying process
Afterwards, slice/section is placed in supersonic wave wall breaking machine, is carried out at supersonic wave wall breaking under conditions of 5~10 DEG C, CO2 gas shield
Reason, obtains traditional Chinese medicine powder；
S3, by resulting traditional Chinese medicine powder and weighed Honegsukle flower P.E chlorogenic acid, berberine, fucoidin, mushroom
Granulose, astragalus polyose are mixed evenly to get composition.
Embodiment 3
A kind of Chinese medicine composition for treating pig blue-ear disease, as obtained by following steps preparation:
S1, weigh by weight: 17.5 parts of Honegsukle flower P.E chlorogenic acid, 12.5 parts of cordate houttuynia, 12.5 parts of Crisped Ardisia Ardisia gigantifolia,
12.5 parts of berberine, 8 parts of dandelion, 10 parts of campanulaceae, 12.5 parts of origanum oil, 10 parts of perilla leaf, 15 parts of fucoidin, Mao great
Fourth grass 5 parts, 6 parts of Lentinan, 8 parts of tassel flower, 7.5 parts of schizonepeta, 12.5 parts of wilsonii, 4 parts of hawthorn, 7 parts of reed root, Radix Glycyrrhizae 4
Part, 12 parts of astragalus polyose；
S2, by weighed cordate houttuynia, Crisped Ardisia Ardisia gigantifolia, dandelion, campanulaceae, origanum oil, perilla leaf, pilose gerbera herb, tassel flower,
Schizonepeta, wilsonii, hawthorn, reed root and Radix Glycyrrhizae are cleaned and drain, and are placed in far infrared drying oven, 50~70 DEG C of 3~7h of drying process
Afterwards, slice/section is placed in supersonic wave wall breaking machine, is carried out at supersonic wave wall breaking under conditions of 5~10 DEG C, CO2 gas shield
Reason, obtains traditional Chinese medicine powder；
S3, by resulting traditional Chinese medicine powder and weighed Honegsukle flower P.E chlorogenic acid, berberine, fucoidin, mushroom
Granulose, astragalus polyose are mixed evenly to get composition.
Test example 1:
1, test grouping: piglet and Adult Pig each 100 of the choosing with blue otopathy amount to 200, male and female dual-purpose is divided into
Piglet group and Adult Pig group.
Piglet group is randomly divided into a, b, c, d group, every group 25, wherein a group is blank control group, and b is to use antibiotic
Group, c are the Chinese medicine composition group using embodiment 3, and d is the Chinese medicine composition group using embodiment 1.
Adult Pig group is randomly divided into A, B, C, D group, every group 25, wherein A group is blank control group, and B is to use antibiosis
Plain group, C is the Chinese medicine composition group using embodiment 3, and D is the Chinese medicine composition group using embodiment 2.
2, diagnostic criteria:
Body temperature is up to 40 DEG C or more, and expiratory dyspnea is in abdominal respiration, appetite stimulator or abolish sometimes, and diarrhea peels off, solely
Place or mutual huddling together, coat is slightly random, muscular tremor, unstable incoordination of walking, four limbs outreach, and posterior paralysis is gradual
Syntexis, palpebral edema.Some piglet performance mouth and nose surprises are itched, and on colony house friction wall column, nose has batter shape or water for common nose disk, mouth end
Sample secretion.
3, treatment method:
B and b group: antibiotic is per daily 3~5 times, and 20ml is administered in administration 5ml, Adult Pig every to piglet every every time every time,
It is used in conjunction 14 days；It feeds in a conventional manner；
C, d, C, D group: Chinese medicine composition is mixed into feed, is conventionally fed, and each mixed volume is that feed is total
The 0.2% of quality is used continuously 14 days, the 15th day observation treatment condition.
A, it A group: conventionally feeds；
4, efficacy assessment standard:
Effective: temperature of pig body is normal, no diarrhea, and breathing is normal, no oedema, and spirit, appetite are normal；
Improve: temperature of pig body is normal, no diarrhea, there is mild respiratory symptom, and spirit, appetite are normal；
It is invalid: improvement standard or death is not achieved.
5, treatment results
| Group | Invalid head number | Survival rate | Cure rate |
| a | 25 | 5% | 0 |
| A | 25 | 3% | 0 |
| b | 5 | 19% | 13% |
| B | 3 | 20% | 15% |
| c | 3 | 81% | 79% |
| C | 2 | 83% | 81% |
| d | 4 | 82% | 80% |
| D | 3 | 85% | 82% |
Specific embodiments of the present invention are described above.It is to be appreciated that the invention is not limited to above-mentioned
Particular implementation, those skilled in the art can make a variety of changes or modify within the scope of the claims, this not shadow
Ring substantive content of the invention.In the absence of conflict, the feature in embodiments herein and embodiment can any phase
Mutually combination.
Claims (6)
1. a kind of Chinese medicine composition for treating pig blue-ear disease, it is characterised in that: prepare gained by following raw material:
15~20 parts of Honegsukle flower P.E chlorogenic acid, 10~15 parts of cordate houttuynia, 10~15 parts of Crisped Ardisia Ardisia gigantifolia, berberine 10~
15 parts, 6~10 parts of dandelion, 8~12 parts of campanulaceae, 10~15 parts of origanum oil, 8~12 parts of perilla leaf, 10~20 parts of fucoidin,
3~7 parts of pilose gerbera herb, 4~8 parts of Lentinan, 4~12 parts of tassel flower, 5~10 parts of schizonepeta, 10~15 parts of wilsonii, hawthorn
3~5 parts, 6~8 parts of reed root, 3~5 parts of Radix Glycyrrhizae, 6~18 parts of astragalus polyose.
2. a kind of Chinese medicine composition for treating pig blue-ear disease as described in claim 1, it is characterised in that: prepared by following raw material
Gained:
15 parts of Honegsukle flower P.E chlorogenic acid, 10 parts of cordate houttuynia, 10 parts of Crisped Ardisia Ardisia gigantifolia, 10 parts of berberine, 6 parts of dandelion,
8 parts of campanulaceae, 10 parts of origanum oil, 8 parts of perilla leaf, 10 parts of fucoidin, 3 parts of pilose gerbera herb, 4 parts of Lentinan, tassel flower 4
Part, 5 parts of schizonepeta, 10 parts of wilsonii, 3 parts of hawthorn, 6 parts of reed root, 3 parts of Radix Glycyrrhizae, 6 parts of astragalus polyose.
3. a kind of Chinese medicine composition for treating pig blue-ear disease as described in claim 1, it is characterised in that: prepared by following raw material
Gained:
20 parts of Honegsukle flower P.E chlorogenic acid, 15 parts of cordate houttuynia, 15 parts of Crisped Ardisia Ardisia gigantifolia, 15 parts of berberine, 10 parts of dandelion,
12 parts of campanulaceae, 15 parts of origanum oil, 12 parts of perilla leaf, 20 parts of fucoidin, 7 parts of pilose gerbera herb, 8 parts of Lentinan, tassel flower
12 parts, 10 parts of schizonepeta, 15 parts of wilsonii, 5 parts of hawthorn, 8 parts of reed root, 5 parts of Radix Glycyrrhizae, 18 parts of astragalus polyose.
4. a kind of Chinese medicine composition for treating pig blue-ear disease as described in claim 1, it is characterised in that: prepared by following raw material
Gained:
17.5 parts of Honegsukle flower P.E chlorogenic acid, 12.5 parts of cordate houttuynia, 12.5 parts of Crisped Ardisia Ardisia gigantifolia, 12.5 parts of berberine, Pu
8 parts of public English, 10 parts of campanulaceae, 12.5 parts of origanum oil, 10 parts of perilla leaf, 15 parts of fucoidin, 5 parts of pilose gerbera herb, Lentinan 6
Part, 8 parts of tassel flower, 7.5 parts of schizonepeta, 12.5 parts of wilsonii, 4 parts of hawthorn, 7 parts of reed root, 4 parts of Radix Glycyrrhizae, 12 parts of astragalus polyose.
5. a kind of Chinese medicine composition for treating pig blue-ear disease as described in claim 1, it is characterised in that: the composition by with
Lower step preparation gained:
S1, each component is weighed by weight；
S2, by weighed cordate houttuynia, Crisped Ardisia Ardisia gigantifolia, dandelion, campanulaceae, origanum oil, perilla leaf, pilose gerbera herb, tassel flower, chaste tree
Mustard, wilsonii, hawthorn, reed root and Radix Glycyrrhizae are cleaned and drain, and are placed in far infrared drying oven after drying, slice/section is placed in ultrasonic wave
In wall-breaking machine, supersonic wave wall breaking processing is carried out under conditions of 5~10 DEG C, CO2 gas shield, obtains traditional Chinese medicine powder；
It is S3, resulting traditional Chinese medicine powder and weighed Honegsukle flower P.E chlorogenic acid, berberine, fucoidin, Lenlinus edodes are more
Sugar, astragalus polyose are mixed evenly to get composition.
6. a kind of Chinese medicine composition for treating pig blue-ear disease as claimed in claim 5, it is characterised in that: in the step S2,
The temperature of far-infrared ray drying is 50~70 DEG C, and the time is 3~7h.
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Cited By (1)
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| CN110432399A (en) * | 2019-09-19 | 2019-11-12 | 临沂大学 | A kind of fattening pannage additive and preparation method thereof |
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| CN107998332A (en) * | 2018-02-05 | 2018-05-08 | 河南翔大生物科技有限公司 | A kind of Chinese medicine composition for treating pig blue-ear disease and its application |
| CN109432217A (en) * | 2018-12-06 | 2019-03-08 | 湖北隆博旺畜牧服务有限公司 | A kind of chitosan oligosaccharide is used to prevent and treat the feed formula of pig blue-ear disease |
| CN109498791A (en) * | 2018-12-28 | 2019-03-22 | 塔里木大学 | Granular preparation is used in a kind of red deer respiratory tract infection treatment |
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| CN109432217A (en) * | 2018-12-06 | 2019-03-08 | 湖北隆博旺畜牧服务有限公司 | A kind of chitosan oligosaccharide is used to prevent and treat the feed formula of pig blue-ear disease |
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Application publication date: 20190625 |