CN109862834B - 具有接合剂递送通道的可弯曲的骨凿 - Google Patents
具有接合剂递送通道的可弯曲的骨凿 Download PDFInfo
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Abstract
本公开示出用于治疗硬组织的骨凿。本文描述的所述骨凿实施方案包括轴,所述轴具有工作端部,所述工作端部被构造成移位硬组织和管腔以通过所述轴递送材料。通过选择性地从线性构型转变到非线性构型,所述工作端部可形成通路。当所述工作端部处于线性构型或允许所述通路的精确填充的非线性构型时,所述管腔可通过所述轴递送材料。
Description
相关申请
本申请要求2016年10月27日提交的并且标题为“Articulating Osteotome withCement Delivery Channel(具有接合剂递送通道的可弯曲的骨凿)”的美国临时申请No.62/413,768的优先权,该申请据此全文以引用方式并入。
技术领域
本公开整体涉及用于治疗骨或硬组织的系统和方法。更特别地,一些实施方案涉及用于在锥骨中形成路径或腔并注射骨接合剂以治疗锥骨压缩骨折的医疗器械和方法。
附图说明
本文的书面公开内容描述了非限制性和非详尽的示例性实施方案。对附图中示出的此类示例性实施方案中的某些进行了参照,其中:
图1是根据一个实施方案的用于治疗硬组织的医疗装置的透视图。
图2是根据一个实施方案的用于治疗硬组织的医疗装置的尖端的透视图。
图3是根据一个实施方案的用于治疗硬组织的医疗装置的可弯曲的部分的透视图。
图4是根据一个实施方案的用于治疗硬组织的医疗装置的侧剖视图。
图5是根据一个实施方案的具有半圆柱形部分的轴的内杆的透视图。
图6是根据一个实施方案的具有管心针的管腔的透视图。
图7是根据一个实施方案的医疗装置的顶部剖视图。
图8示出处于线性构型的轴的可弯曲的部分的剖视图。
图9示出处于第一弯曲构型的图8的可弯曲的部分。
图10示出处于第二弯曲构型的图8的可弯曲的部分。
图11示出插入椎体中的导引器。
图12示出在图11的椎体中形成通路的骨凿。
图13是正通过骨凿中的管腔注射到图12的通路中的骨接合剂的剖视图。
图14是根据一个实施方案的用于治疗流体地耦接到骨接合剂注射器的硬组织的医疗装置的透视图。
具体实施方式
本公开提供通过在骨或其他硬组织内形成和填充腔来治疗硬组织的方法和系统。用于治疗硬组织的医疗装置可包括具有可弯曲的部分的轴、被构造成操纵可弯曲的部分的柄部、延伸到轴的可接取部分的侧端口、以及在插入到侧端口中的管腔。在一个实施方案中,医师可将轴的可弯曲的部分推进到椎体中。医师可操纵柄部以引起可弯曲的部分从线性构型移动到非线性构型。可弯曲的部分的构型的改变可使椎体中的组织移位,从而形成通路。当可弯曲的部分处于允许通路的精确填充的非线性构型时,医师可通过管腔注射骨接合剂。
轴可包括导管和杆。导管可具有沿着远侧部分的第一侧的一系列狭槽。狭槽可允许远侧部分偏转,从而形成导管的可弯曲的远侧部分。杆可包括延伸穿过导管的半圆柱形部分。半圆柱形部分的形状可允许杆在施加力时挠曲,并在力被移除时返回到线性位置。
杆可耦接到导管的远侧端部。在一些实施方案中,杆和导管可直接附接。例如,杆和导管可在远侧端部处焊接在一起。焊接可沿着杆和导管的远侧尖端。在一些实施方案中,焊接可设置在导管的附加的凹口、孔或狭槽处,由此增大导管和杆的焊接表面区域。换句话讲,焊接接头可围绕凹口、孔或狭槽的周边形成,以将杆附接到导管。
杆可延伸穿过导管。杆可沿着导管的第一侧上的狭槽延伸。狭槽在导管中的位置,以及杆相对于导管的相对位置,可限制可弯曲的远侧部分在一个平面中的移动。在一些实例中,当杆在近侧方向上平移时(不移位导管),在杆和导管之间的耦接和定位可引起杆和导管在可弯曲的远侧部分处挠曲。
轴还可包括位于导管的可弯曲的远侧部分的端部处的尖锐尖端以刺透硬组织。在一些实施方案中,尖端可由导管和/或杆形成。在另一实施方案中,尖锐尖端可为耦接到导管和/或杆的单独的部分。可弯曲的远侧部分和尖端可具有足够的强度以机械地移位在患者的椎骨内的组织。
柄部可包括耦接到杆的近侧端部的致动部分。致动部分的移动可导致杆的相关联的移动。例如,致动部分可控制杆的轴向移动。在一些实施方案中,致动部分的旋转可导致杆的近侧移动。因此,通过将致动部分旋转所选择的量,可弯曲的部分可可弯曲的至所选择的角度,并且可弯曲的远侧部分可选择性地在线性构型和可弯曲的构型之间移动。
柄部还可包括力限制器。如果目标力施加在致动部分上,则力限制器可使致动部分与杆的近侧端部脱离接合。目标力可在可弯曲的远侧部分的断裂点附近。力限制器可防止可弯曲的远侧部分断裂。
类似地,在一些实例中,整个导管和杆组件可经由离合器或扭矩限制组件耦接到柄部。此类组件可限制可从柄部传输到导管和杆组件的扭矩的量。该扭矩限制组件可减少由于柄部施加的过大的力而导致的杆和/或导管的断裂。
在包括扭矩限制器的一些实施方案中,接合剂或其他物质可借助梭动部件沿着通过扭矩限制器组件的注射路径为能够移位的。梭动部件可为相对于导管能够旋转地移位的,并且可包括围绕其圆周的开口以形成流体路径,无论梭动件相对于导管的旋转位置为何。
侧端口可耦接到柄部。侧端口可具有延伸到导管的可接取部分或工作通道的插入引导件。导管的工作通道或可接取部分可为未由杆的半圆柱形部分占据的部分。管腔可插入到可接取部分中。
插入的管腔可延伸穿过导管到达可弯曲的远侧部分中的开口。管腔可为中空半圆柱体,其为材料提供穿过导管的路径。管腔可包括表面,该表面包括润滑聚合物材料。例如,材料可包括具有低摩擦性能的任何生物相容材料(例如聚四氟乙烯(PTFE)、FEP(氟化乙烯丙烯)、聚乙烯、聚酰胺、ECTFE(乙烯氯三氟-乙烯)、ETFE、PVDF、聚氯乙烯和有机硅)。与杆类似,管腔可为半圆柱形。半圆柱形杆和管腔可定位在导管内以形成填充导管的圆柱体。
管腔端口可耦接到管腔。管腔端口可包括夹具。夹具可通过夹具皮套将管腔端口固定到侧端口。由于在半圆柱形可接取部分内难以旋转半圆柱形管腔,杆和管腔的半圆柱形形状可防止使用螺纹连接器固定管腔。夹具提供将不需要管腔旋转的附接方法。管腔端口可选择性地耦接到热能递送探头、接合剂递送筒及活体组织检查工具。管腔也可为能够选择性地移除和替换的。例如,如果接合剂开始阻塞管腔,新的管腔可替换阻塞的管腔。
在一些实施方案中,可选择性地将管心针插入管腔中。管心针可延伸穿过管腔用于对可弯曲的远侧部分的附加的支撑。管心针可为填充管腔的柔性材料。可移除管心针以允许使用附加的工具和接合剂。
短语“耦接到”足够宽泛至指在两个或更多个实体之间的任何合适的耦接或其他形式的相互作用,包括机械、流体和热相互作用。因此,两个部件可耦接到彼此,即便其不与彼此直接接触。短语“附接到”或“直接附接到”是指彼此直接接触和/或仅通过任何合适的种类的紧固件(例如,安装硬件或粘合剂)彼此分开的在两个或更多个实体之间的相互作用。短语“流体连通”以其普通意义被使用,并且足够宽泛至指其中当元件彼此流体连通时流体(例如,气体或液体)可从一个元件流向另一个元件的布置方式。
术语“近侧”和“远侧”是相反的方向术语。例如,装置或部件的远侧端部是在正常使用期间距离医师最远的部件的端部。近侧端部是指相反的端部,或者是在正常使用期间最靠近医师的端部。
如本文的图中总体描述且示出的实施方案的部件可被布置并设计成多种不同的构型。因此,以下对在图中所表示的各种实施方案的更详细描述不旨在限制本公开的范围,而是仅仅表示各种实施方案。尽管在附图中呈现了实施方案的各种方面,除非明确指示,否则附图未必按比例绘制。
图1是根据一个实施方案的用于治疗硬组织的医疗装置100的透视图。在一个实施方案中,医疗装置100可为骨凿,该骨凿被构造成用于进入椎体的内部、在锥骨松质骨中形成通路、以及用骨接合剂填充通路。医疗装置100可包括轴102、柄部104、侧端口106、以及管腔108。
在使用中,医师可通过患者脊柱的椎弓根将轴102引入。轴可包括导管112和半圆柱形杆114。导管112和杆114可由合适的金属合金诸如不锈钢或NiTi制成。轴可构造有可弯曲的部分110。可弯曲的部分110可基于在导管112和半圆柱形杆114之间的耦接沿着一个平面偏转。例如,如图所示,半圆柱形杆114可与导管112上的一系列狭槽邻接并沿着导管112上的一系列狭槽延伸。一系列狭槽可允许导管112弯曲并且半圆柱形杆的形状可允许半圆柱形杆弯曲。可弯曲的部分110可位于轴的远侧端部处。
可弯曲的部分110可渐进地致动以弯曲所选择的角度和/或旋转以在椎体中形成弯曲通路和腔。管腔108可通过侧端口106插入并延伸穿过轴102以提供骨接合剂经过的通路。可弯曲的部分110可保持处于弯曲状态,而骨接合剂可直接注射到腔中。
柄部104可耦接到轴102的近侧端部。柄部104可包括抓持部分116以及致动器部分118。抓持部分116可耦接到导管112。并且致动器部分118可操作地耦接到半圆柱形杆114。轴102可耦接到柄部104,以允许医师将轴102驱动到骨中,同时将可弯曲的部分110致动到可弯曲的构型或弯曲构型。柄部104可由聚合物、金属或任何其他材料制成。在一些实施方案中,柄部104的材料可适于承受用于将组件驱动到骨中的锤击力或冲击力(例如,经由在柄部104上使用锤或类似装置)。
致动器部分118可为相对于抓持部分116能够旋转的。当致动器部分118转动时,可弯曲的部分110可相关联地偏转。一些实施方案可具有用于止动致动器部分118的移动并由此保持可弯曲的部分110的偏转的系统或元件。例如,在一个实施方案中,抓持部分的一个或多个塑料挠曲突片可被构造成接合能够旋转的致动器部分中的凹口以在一定程度的旋转中提供触觉指示和临时锁定。
侧端口106可提供孔口,该孔口穿过柄部104进入未由半圆柱形杆、可接取部分或工作通道124占据的轴102的一部分。管腔108可插入侧端口106中并沿着工作通道124延伸穿过轴102。管腔108可通过夹具120固定到侧端口106。管腔108还可包括螺纹端口122以接受接合剂递送装置、活体组织检查工具以及其他医疗器械。在图1中示出的实施方案中,管心针126经由螺纹端口122耦接到管腔108。
图2是根据一个实施方案的用于治疗硬组织的医疗装置的尖端200的透视图。如图所示,导管202可涵盖杆204以及管腔206。图2中示出的尖端200的实施方案是图1的医疗装置100的尖端的示例。换句话讲,图2的尖端200的各种特征可结合图1的医疗装置100使用,并且反之亦然。结合图1所述的公开内容可不结合图2进行重复,但是此类公开内容类似地适用于图2的尖端200,并且反之亦然。该公开的图案适用于本申请中所述的每个图和实施方案,每个实施方案的特征可被理解为类似地应用到其他实施方案。
导管可具有一系列狭槽208。套筒中的任一个中的凹口或狭槽可沿着工作端部的长度包括均匀的宽度或者可包括变化的宽度。另选地,可在特定区域中选择宽度以实现特定弯曲轮廓。在其他变型中,宽度可沿着工作端部增大或减小以形成具有变化半径的曲线。
如图所示,杆204和管腔206二者可均为半圆柱形。当配对在一起时,它们的形状和尺寸设定可形成圆柱体,该圆柱体填充导管202的中心。管腔可对尖端200提供附加的支撑。
图3是根据一个实施方案的用于治疗硬组织的医疗装置的可弯曲的部分300的底部视图。图3中示出的可弯曲的部分300的实施方案是图1的医疗装置100的尖端的示例。换句话讲,图2的可弯曲的部分300的各种特征可结合图1的医疗装置100使用,并且反之亦然。结合图1所述的公开内容可以不结合图3进行重复,但是此类公开内容类似地适用于图3的可弯曲的部分300,并且反之亦然。
半圆柱形杆302可以各种方式附接到导管304。例如,半圆柱形杆的弧形的周边可在端部处焊接到导管304。其他附接点可用于将半圆柱形杆302固定到导管304。例如,所示焊接凹口306提供焊接区域以将半圆柱形杆302附接到导管304。在一些实施方案中,多个附接装置可用于将导管304附接到半圆柱形杆302。
图4是根据一个实施方案的用于治疗硬组织的医疗装置400的剖视图。如图所示,医疗装置400可包括杆402、柄部406、侧端口408、管腔410和导管412。医疗装置400的该剖视图是图1的医疗装置100的示例。换句话讲,图4的医疗装置400的各种特征可结合图1的医疗装置100使用,并且反之亦然。结合图1所述的公开内容可不结合图4进行重复,但是此类公开内容类似地适用于图4的医疗装置400,并且反之亦然。
杆402可包括圆柱形近侧端部414和半圆柱形远侧端部416。圆柱形近侧端部414可机械地耦接到柄部406的致动器部分404。在致动器部分404和圆柱形近侧端部414之间的机械耦接可将致动器部分404的旋转转换成沿着杆402的轴线的力。半圆柱形远侧端部416可延伸穿过导管412并占据导管的底部部分。半圆柱形远侧端部416由于其形状与圆柱形近侧端部414相比可为柔性的。
致动器部分404可移位圆柱形近侧端部414。圆柱形近侧端部414的移位在半圆柱形远侧端部416上施加力。半圆柱形远侧端部416可附接到导管412,引起半圆柱形远侧端部416上的力将杆402和导管706弯曲。
管腔410可经由侧端口408进入导管412。如图所示,侧端口408可位于柄部406的上部部分上。侧端口408可包括孔口418,该孔口通向导管412的上部部分。医师可通过孔口418插入管腔。管腔410可延伸穿过导管412,使得侧端口在导管412的远侧端部处具有第一开口420,并在侧端口408处具有第二开口422。
在一些实施方案中,管腔410可通过夹具424固定到侧端口。由于杆402和管腔410的半圆柱形形状,标准的螺纹固定机构可不能正常工作。例如,在其中管腔410在导管412中没有旋转空间的实施方案中,标准的螺纹固定机构将不会工作。夹具424提供将管腔固定到侧端口408的另选方案,无需管腔410旋转。管腔还可包括螺纹附接点426以选择性地耦接到管心针、热能递送探头、接合剂递送筒、或活体组织检查工具。
图5是轴的内杆500的透视图。图5的内杆500是图1中的杆114的示例。结合图1所述的公开内容可不结合图5进行重复,但是此类公开内容类似地适用于图5的医疗装置500,并且反之亦然。
内杆可包括圆柱形部分502和半圆柱形部分504。圆柱形部分502可提供非旨在弯曲的内杆500的刚性长度。半圆柱形部分504可经由其形状被构造成在向其施加力时挠曲。如图所示,在圆柱形部分502和半圆柱形部分504之间的变窄可为迅速的。在另选的实施方案中,圆柱形部分502可逐渐变窄到半圆柱形部分504以允许在内杆500的一些点处的柔性比其他点更大。
图6是根据一个实施方案的具有管心针608的管腔600的透视图。如图所示,管腔600可包括衬里602、侧端口夹具604、以及螺纹配合机构606。图6的管腔600是图1中的管腔108的示例。结合图1所述的公开内容可不结合图6进行重复,但是此类公开内容类似地适用于图6的管腔600,并且反之亦然。
管腔600可以附加的强度对医疗装置提供附加的支撑以治疗硬组织,并允许材料从一个端部经过另一个端部。第一开口612可允许材料诸如骨接合剂进入管腔600。第二开口614可允许通过第一开口612进入管腔600中的材料流出。另选地,可从第二开口614将材料从第一开口612抽出,用于诸如活体组织检查的程序。侧端口夹具604可将管腔600固定到医疗装置,并且螺纹配合机构606可将管腔固定到附加的工具诸如热能递送探头、接合剂递送筒、或活体组织检查工具。
管心针可包括盖610以经由螺纹配合机构606将管心针608固定到管腔600。盖610还可防止异物通过管腔600进入椎骨。管心针608可为支撑性的,使得当管心针608插入管腔600时,所得的组合比单独管腔600更具刚性。这可对医疗装置提供附加的强度以治疗硬组织。在一些实施方案中,管心针608可为非常柔性的以更大程度地移动医疗装置。在另选的实施方案中,管心针608可为半刚性的用于额外支撑。
图7是根据一个实施方案的医疗装置700的顶部剖视图。如图所示,医疗装置700可包括用于致动的机构702,用于相对于导管706致动杆704。医疗装置700的该顶部剖视图是图1的医疗装置100的示例。换句话讲,图7的医疗装置700的各种特征可结合图1的医疗装置100使用,并且反之亦然。该医疗装置700也是图4的医疗装置400的示例,其中横截面沿着不同平面截取。结合图1所述的公开内容可不结合图7进行重复,但是此类公开内容类似地适用于图7的医疗装置700,并且反之亦然。
导管706可静态地附接到柄部708。在一些实施方案中,导管706可经由焊接、O形环、模塑、和/或夹紧件附接到柄部708。该附接可防止导管706相对于柄部708移动或旋转。导管706还可在远侧尖端712处或附近附接到杆704。
杆704可附接到在近侧端部处用于致动的机构702。用于致动的机构702可选择性地朝向或远离远侧尖端712平移杆704。平移可引起杆704在导管706和杆704之间的附接点处推动或拉动。因为导管706相对于柄部是静止的,推动或拉动可引起杆704和导管706偏转。
用于致动的机构702可耦接到柄部的致动器部分716。用于致动的机构702可包括螺纹致动器718以及具有螺纹配合轴承722的蛤壳720。螺纹致动器718可耦接到致动器部分,使得当医师旋转致动器部分716时,螺纹致动器718也旋转。蛤壳720可附接到杆704并通过螺纹配合轴承722接合螺纹致动器718。随着螺纹致动器718旋转,螺纹配合轴承722可沿着螺纹致动器718的螺纹滑动,防止蛤壳720旋转,同时朝向或远离远侧尖端712平移蛤壳。
用于致动的机构702可移位杆704的近侧端部。杆704的近侧端部的移位在杆704的远侧端部上施加力。因为杆704的远侧端部附接到导管706,杆704的远侧端部上的力引起杆704和导管706挠曲。
图8至图10示出处于线性构型和第一弯曲构型及第二弯曲构型的轴的可弯曲的部分800的剖视图。可弯曲的部分800可类似于图1的可弯曲的部分110。图1的可弯曲的部分110可类似于图8的可弯曲的部分800操作,并且反之亦然。
可弯曲的部分800弯曲的能力由于导管806中的凹口804以及杆802的形状。杆的半圆柱形形状引起其具有比杆为圆柱形时更大的柔性,以允许杆802弯曲。可弯曲的部分800的方向可由导管806中凹口804的位置限制。例如,可弯曲的部分800可仅沿着凹口804的平面弯曲。可弯曲的部分800在任何其他方向上是刚性的。任何可弯曲的构型的曲率通过凹口的间距以及在每个凹口峰之间的距离控制。
图8示出处于线性构型的可弯曲的部分800。图9示出处于第一弯曲构型的可弯曲的部分800。当杆802在远侧方向上推动导管806时,引起第一弯曲构型。例如,杆802可在尖端附近焊接到导管806。因为杆附接到导管,所以当导管806保持静止时推动杆802的力将引起杆802推动导管806的尖端,引起其挠曲以允许杆在远侧方向上移动。图10示出处于第二弯曲构型的可弯曲的部分800。当杆802在近侧方向上拉动导管806时,引起第二弯曲构型。例如,杆802可在尖端附近焊接到导管806。因为杆附接到导管,所以当导管806保持静止时拉动杆802的力将引起杆802拉动导管806的尖端,引起其挠曲以允许杆在近侧方向上移动。
图11至图13是根据一个示例性方法的使用中的骨凿的剖视图。该方法可包括获得具有尖锐尖端的医疗装置,该尖锐尖端被构造用于刺入锥骨中,该医疗装置包括,并将工作端部推进到椎体中。一旦进入椎体,医师可引起工作端部从线性构型移动到非线性构型以在椎体中形成通路。医师可在工作端部处于非线性构型时进一步通过管腔注射流体,从而以精确模式用流体填充通路。
图11示出正插入椎体1106中的导引器1100。医师通常将导引器1100和套筒1105轻击或以其他方式驱动到椎体1106中,直至导引器尖端1108朝向皮质骨1110在椎体的前部1/3内。
然后,移除导引器1100并朝近侧移动套筒1105(图12)。如在图12中可见,工具或骨凿1200通过导引器套筒1105插入并且可弯曲的。骨凿1200可为图1中的医疗装置100。在向骨凿的柄部施加驱动力和任选地旋转力以推进工作端部穿过松质骨1212以形成路径或腔1215时,工作端部1210可间歇地可弯曲。然后轻击工具以进一步将工作端部1210驱动到椎骨的中线、朝向或超过椎骨的中线驱动工作端部。医师可另选地可弯曲的工作端部1210,并进一步驱动和旋转工作端部,直至成像显示工作端部1210已形成最佳构型的腔1215。
然后,如图13中所示,医师可在工作端部1210处于非线性构型时,通过管腔1324注射骨接合剂1322。在工作端部1210处于非线性构型时注射骨接合剂1322的能力为医师提供对于如何填充路径或腔的精准控制。
图14是根据一个实施方案的用于治疗流体地耦接到骨接合剂注射器1402的硬组织的医疗装置1400的透视图。如图所示,注射器1402可通过接合管腔1408的螺纹配合机构1406耦接到医疗装置1400。医师可使用注射器1402来通过管腔1408推动接合剂。接合剂可行进通过医疗装置1400并流出远侧尖端1410。
本文所公开的任何方法包括用于执行所述方法的一个或多个步骤或动作。所述方法步骤和/或动作可彼此互换。换句话讲,除非对于实施方案的正确运行需要特定顺序的步骤或动作,否则可修改特定步骤和/或动作的顺序和/或用途。此外,本文所述方法的子程序或仅一部分可是在本公开范围内的单独的方法。换句话讲,一些方法可仅包括在更详细的方法中描述的步骤的一部分。
本说明书通篇对“实施方案”或“所述实施方案”的提及意指,结合该实施方案所述的特定特征、结构或特性包括在至少一个实施方案中。因此,如本说明书通篇所述,引用的短语或其变型不一定全部涉及相同实施方案。
类似地,受益于本公开的本领域的技术人员应当认识到,为了使本公开简化,在上述实施方案的描述中,有时将多个特征一起集中在单个实施方案、图或其描述中。然而,这种公开的方法不应解释为反映以下意图,即任何权利要求需要比该权利要求中明确列举的那些特征更多的特征。相反,如以下权利要求书所反映,本发明的方面在于比任何单个前述公开的实施方案的所有特征更少的特征的组合。因此,该具体实施方式后的权利要求书据此明确地并入到该具体实施方式中,其中每个权利要求独立地作为单独的实施方案。本公开包括独立权利要求与其从属权利要求的所有排列。
权利要求书中关于特征或元件的术语“第一”的叙述不一定暗示存在第二或附加的此类特征或元件。对于受益于本公开的本领域的技术人员将显而易见的是,可在不脱离本公开的基本原理的情况下对上述实施方案的细节作出改变。
Claims (21)
1.一种医疗装置,所述医疗装置用于治疗硬组织,包括:
导管,所述导管具有沿着所述导管的可弯曲的远侧部分的第一侧的一系列狭槽;
杆,所述杆延伸穿过所述导管,所述杆包括柔性部分;
柄部,所述柄部包括耦接到所述杆的近侧端部的致动部分,其中所述致动部分的移动导致所述杆和所述导管的相关联的移动,以选择性地在线性构型和可弯曲的构型之间移动所述可弯曲的远侧部分;
侧端口,所述侧端口通过插入引导件耦接到所述柄部,所述插入引导件延伸到所述导管的可接取部分,所述导管的可接取部分沿着所述导管延伸到所述导管的远侧端部;以及
在所述插入引导件中插入并延伸穿过所述导管的管腔。
2.根据权利要求1所述的医疗装置,还包括管腔端口,所述管腔端口具有耦接到所述管腔的夹具,并且其中所述侧端口包括夹具皮套以将所述管腔端口固定到所述侧端口。
3.根据权利要求2所述的医疗装置,其中所述管腔端口被构造成选择性地耦接到热能递送探头、接合剂递送筒、以及活体组织检查工具。
4.根据权利要求1至3中任一项所述的医疗装置,其中所述管腔为能够选择性地移除和替换的。
5.根据权利要求1至3中任一项所述的医疗装置,其中所述导管包括在所述远侧部分的所述第一侧上的凹口,其中所述导管和杆通过围绕所述凹口的周边的焊接接头附接。
6.根据权利要求1至3中任一项所述的医疗装置,其中所述可弯曲的远侧部分具有足够的强度以机械地移位在患者的椎骨内的组织。
7.根据权利要求1至3中任一项所述的医疗装置,其中所述可弯曲的远侧部分被构造成仅在单个平面中从所述线性构型转变到非线性构型。
8.根据权利要求1至3中任一项所述的医疗装置,其中所述管腔为半圆柱形,并且其中所述杆的柔性部分和所述管腔被定位在所述导管内以形成填充所述导管的圆柱体。
9.根据权利要求1至3中任一项所述的医疗装置,还包括管心针,所述管心针选择性地插入所述管腔中并且延伸穿过所述管腔用于对所述可弯曲的远侧部分的附加的支撑。
10.根据权利要求1至3中任一项所述的医疗装置,其中所述柄部还包括力限制器,当目标力施加在所述致动部分上时,所述力限制器使所述致动部分与所述杆的所述近侧端部脱离接合。
11.根据权利要求1至3中任一项所述的医疗装置,其中所述柔性部分包括耦接到所述导管的所述可弯曲的远侧部分并且与所述导管的所述第一侧邻接的半圆柱形部分。
12.根据权利要求1至3中任一项所述的医疗装置,还包括位于所述导管的所述可弯曲的远侧部分的端部处的尖锐尖端以刺透硬组织。
13.一种医疗装置,所述医疗装置用于治疗在患者的椎骨内的硬组织,所述医疗装置包括:
轴,所述轴具有可弯曲的部分,所述轴包括:
中空导管,所述中空导管具有沿着第一侧的一系列狭槽以允许偏转,以及
半圆柱形杆,所述半圆柱形杆延伸穿过所述中空导管并与所述中空导管的所述第一侧邻接,
其中所述中空导管和半圆柱形杆在所述可弯曲的部分的远侧端部处耦接,使得沿着所述半圆柱形杆的轴线施加的力转换成所述可弯曲的部分中的偏转,以在线性构型和可弯曲的构型之间可逆地移动,其中所述系列狭槽和所述半圆柱形杆将在所述线性构型和所述可弯曲的构型之间的移动限制到单个平面;
侧端口,所述侧端口具有夹具皮套,所述夹具皮套延伸到所述轴的可接取部分,所述轴的可接取部分沿着所述中空导管延伸到所述导管的远侧端部;以及
管腔,所述管腔具有夹具,以选择性地将所述管腔固定到插入引导件,所述管腔延伸穿过在两个端部处具有开口的所述中空导管,以允许材料通过所述轴的移动而不会接触所述轴。
14.根据权利要求13所述的医疗装置,其中所述可弯曲的部分具有足够的强度以机械地移位在患者的椎骨内的组织。
15.根据权利要求13至14中任一项所述的医疗装置,其中所述轴还包括尖的远侧端部,所述尖的远侧端部被构造成刺透在患者的椎骨内的骨。
16.根据权利要求13至14中任一项所述的医疗装置,其中所述管腔包括螺纹接口,以选择性地耦接到热能递送探头、接合剂递送筒、以及活体组织检查工具。
17.根据权利要求13至14中任一项所述的医疗装置,还包括管心针,所述管心针选择性地插入所述管腔中并且延伸穿过所述管腔用于对所述可弯曲的部分的附加的支撑。
18.根据权利要求13至14中任一项所述的医疗装置,还包括柄部,所述柄部包括耦接到所述杆的近侧端部的致动部分,其中所述致动部分的操纵引起所述可弯曲的部分的偏转。
19.根据权利要求18所述的医疗装置,其中所述柄部还包括力限制器,当目标力施加在所述致动部分上时,所述力限制器使所述致动部分与所述杆的所述近侧端部脱离接合。
20.根据权利要求13至14中任一项所述的医疗装置,其中所述管腔为能够选择性地移除和替换的。
21.根据权利要求13至14中任一项所述的医疗装置,其中所述管腔还包括骨接合剂材料源,所述骨接合剂材料源流体地耦接到管腔以使所述骨接合剂材料穿过所述管腔以在所述可弯曲的部分的所述远侧端部处流出。
Applications Claiming Priority (3)
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US62/413,768 | 2016-10-27 | ||
PCT/US2017/058303 WO2018081279A1 (en) | 2016-10-27 | 2017-10-25 | Articulating osteotome with cement delivery channel |
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Country Status (5)
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Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8361067B2 (en) | 2002-09-30 | 2013-01-29 | Relievant Medsystems, Inc. | Methods of therapeutically heating a vertebral body to treat back pain |
US10028753B2 (en) | 2008-09-26 | 2018-07-24 | Relievant Medsystems, Inc. | Spine treatment kits |
US20100298832A1 (en) | 2009-05-20 | 2010-11-25 | Osseon Therapeutics, Inc. | Steerable curvable vertebroplasty drill |
WO2013101772A1 (en) | 2011-12-30 | 2013-07-04 | Relievant Medsystems, Inc. | Systems and methods for treating back pain |
US10588691B2 (en) | 2012-09-12 | 2020-03-17 | Relievant Medsystems, Inc. | Radiofrequency ablation of tissue within a vertebral body |
JP6195625B2 (ja) | 2012-11-05 | 2017-09-13 | リリーバント メドシステムズ、インコーポレイテッド | 骨を通して湾曲経路を作り、骨内で神経を調節するシステム及び方法 |
US9724151B2 (en) | 2013-08-08 | 2017-08-08 | Relievant Medsystems, Inc. | Modulating nerves within bone using bone fasteners |
FR3040869B1 (fr) * | 2015-09-16 | 2017-10-20 | Vexim | Mecanisme de controle de tige orientable |
AU2017363356B2 (en) | 2016-11-28 | 2023-02-09 | Dfine, Inc. | Tumor ablation devices and related methods |
US10470781B2 (en) | 2016-12-09 | 2019-11-12 | Dfine, Inc. | Medical devices for treating hard tissues and related methods |
EP3338646A1 (en) * | 2016-12-21 | 2018-06-27 | National University of Ireland Galway | A biopsy device |
WO2018129180A1 (en) | 2017-01-06 | 2018-07-12 | Dfine, Inc. | Osteotome with a distal portion for simultaneous advancement and articulation |
EP3876856A4 (en) | 2018-11-08 | 2022-10-12 | Dfine, Inc. | TUMORABLATION DEVICE AND RELATED SYSTEMS AND METHODS |
EP4027912A4 (en) | 2019-09-12 | 2023-08-16 | Relievant Medsystems, Inc. | TISSUE MODULATION SYSTEMS AND METHODS |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102500036A (zh) * | 2011-11-17 | 2012-06-20 | 天津科技大学 | 一种磁导航式关节型穿刺针 |
CN102985015A (zh) * | 2010-04-29 | 2013-03-20 | Dfine有限公司 | 用于治疗椎骨骨折的系统 |
CN103690228A (zh) * | 2013-12-12 | 2014-04-02 | 宁波华科润生物科技有限公司 | 椎体扩张球囊系统 |
Family Cites Families (547)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2688329A (en) | 1953-03-19 | 1954-09-07 | American Cystoscope Makers Inc | Catheter |
US3140623A (en) | 1961-08-29 | 1964-07-14 | Pendleton Tool Ind Inc | Predetermined torque release wrench |
US3228400A (en) | 1962-12-03 | 1966-01-11 | Thomas A Armao | Cryogenic capsule probes |
US3503385A (en) | 1965-09-27 | 1970-03-31 | Cordis Corp | Guidable catheter assembly and manipulator therefor |
US3625200A (en) | 1969-08-26 | 1971-12-07 | Us Catheter & Instr Corp | Controlled curvable tip member |
DE1953835B2 (de) | 1969-10-25 | 1972-02-24 | Linde Ag, 6200 Wiesbaden | Kryochirurgisches geraet |
US3664344A (en) | 1970-09-15 | 1972-05-23 | Brymill Corp | Tyned cryosurgical probe |
US3692465A (en) | 1971-05-11 | 1972-09-19 | Samcoe Holding Corp | Three roll processing apparatus,and method for utilization thereof |
US3908637A (en) | 1974-04-22 | 1975-09-30 | Louis W Doroshow | Rigid urethral instrument |
DE2501683C3 (de) | 1975-01-17 | 1979-11-29 | Ernst Leitz Wetzlar Gmbh, 6300 Wetzlar | Polymeres Verbundmaterial für prothetische Zwecke und Verfahren zu seiner Herstellung |
US4033331A (en) | 1975-07-17 | 1977-07-05 | Guss Stephen B | Cardiac catheter and method of using same |
US4900303A (en) | 1978-03-10 | 1990-02-13 | Lemelson Jerome H | Dispensing catheter and method |
DE2862446D1 (en) | 1978-06-29 | 1984-11-15 | Osteo Ag | Carbon fiber reinforced bone cement |
US4276880A (en) | 1978-09-14 | 1981-07-07 | Oscar Malmin | Cannula and process |
US4294251A (en) | 1978-10-17 | 1981-10-13 | Greenwald A Seth | Method of suction lavage |
US4236520A (en) | 1978-12-04 | 1980-12-02 | Anderson Mark L | Fluid drain or injection tube for an animal's udder |
US4276860A (en) | 1979-11-01 | 1981-07-07 | Motorola, Inc. | Apparatus for the generation of monostable pulses having predetermined durations independent of input signal period |
DE2944710A1 (de) | 1979-11-06 | 1981-05-07 | Christos Dr. Dimakos | Vorrichtung zum entfernen einer knochenzementroehre bei einer reimplantation eines kuenstlichen oberschenkelhalskopfes |
DE2949368A1 (de) | 1979-12-07 | 1981-06-11 | Hilti AG, 9494 Schaan | Geraet zum abgeben von ein- oder mehrkomponentenmassen |
US4411266A (en) | 1980-09-24 | 1983-10-25 | Cosman Eric R | Thermocouple radio frequency lesion electrode |
US5017627A (en) | 1980-10-09 | 1991-05-21 | National Research Development Corporation | Composite material for use in orthopaedics |
US4337773A (en) | 1980-10-20 | 1982-07-06 | Raftopoulos Demetrios D | Method of and device for placing a barrier in a cavity provided in a bone shaft |
US4578061A (en) | 1980-10-28 | 1986-03-25 | Lemelson Jerome H | Injection catheter and method |
US4719968A (en) | 1981-01-15 | 1988-01-19 | Speros Phillip C | Heat exchanger |
US4399814A (en) | 1981-04-27 | 1983-08-23 | Massachusetts Institute Of Technology | Method and apparatus for pressure-coated bones |
US4473077A (en) | 1982-05-28 | 1984-09-25 | United States Surgical Corporation | Surgical stapler apparatus with flexible shaft |
US4595006A (en) | 1982-08-16 | 1986-06-17 | Burke Dennis W | Apparatus for cemented implantation of prostheses |
US4456017A (en) | 1982-11-22 | 1984-06-26 | Cordis Corporation | Coil spring guide with deflectable tip |
DE3325111A1 (de) | 1983-07-12 | 1985-01-24 | Merck Patent Gmbh, 6100 Darmstadt | Implantationsmaterialien |
US4722948A (en) | 1984-03-16 | 1988-02-02 | Dynatech Corporation | Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone |
CA1227902A (en) | 1984-04-02 | 1987-10-13 | Raymond G. Tronzo | Fenestrated hip screw and method of augmented internal fixation |
US4682596A (en) | 1984-05-22 | 1987-07-28 | Cordis Corporation | Electrosurgical catheter and method for vascular applications |
US4619263A (en) | 1984-05-30 | 1986-10-28 | Advanced Cardiovascular Systems, Inc. | Adjustable rotation limiter device for steerable dilatation catheters |
US4586923A (en) | 1984-06-25 | 1986-05-06 | Cordis Corporation | Curving tip catheter |
US5114414A (en) | 1984-09-18 | 1992-05-19 | Medtronic, Inc. | Low profile steerable catheter |
US4888366A (en) | 1984-10-24 | 1989-12-19 | Collagen Corporation | Inductive collagen-based bone repair preparations |
US5246457A (en) | 1985-03-28 | 1993-09-21 | Collagen Corporation | Xenogeneic collagen/mineral preparations in bone repair |
US4668295A (en) | 1985-04-25 | 1987-05-26 | University Of Dayton | Surgical cements |
US4627434A (en) | 1985-05-03 | 1986-12-09 | Murray William M | Bone cement system and method |
US4742817A (en) | 1985-05-15 | 1988-05-10 | Olympus Optical Co., Ltd. | Endoscopic apparatus having a bendable insertion section |
CH667209A5 (de) | 1985-07-02 | 1988-09-30 | Sulzer Ag | Medizinische depotsonde. |
US4641654A (en) | 1985-07-30 | 1987-02-10 | Advanced Cardiovascular Systems, Inc. | Steerable balloon dilatation catheter assembly having dye injection and pressure measurement capabilities |
US4846814A (en) | 1986-01-16 | 1989-07-11 | Sherwood Medical Company | Non-whip catheter |
US4795602A (en) | 1986-03-19 | 1989-01-03 | Pretchel David A | Two pin shunt and molding method |
DE3613213A1 (de) | 1986-04-18 | 1987-10-22 | Merck Patent Gmbh | Tricalciumphosphat fuer implantationsmaterialien |
US4747840A (en) | 1986-09-17 | 1988-05-31 | Ladika Joseph E | Selective pulmonary arteriograph catheter |
US4843112A (en) | 1987-03-12 | 1989-06-27 | The Beth Israel Hospital Association | Bioerodable implant composition |
US5085861A (en) | 1987-03-12 | 1992-02-04 | The Beth Israel Hospital Association | Bioerodable implant composition comprising crosslinked biodegradable polyesters |
US4748969A (en) | 1987-05-07 | 1988-06-07 | Circon Corporation | Multi-lumen core deflecting endoscope |
US4898156A (en) | 1987-05-18 | 1990-02-06 | Mitek Surgical Products, Inc. | Suture anchor |
US4784638A (en) | 1987-09-17 | 1988-11-15 | Neurodynamics, Inc. | Angled hole ventricular catheter and method of making same |
US4865586A (en) | 1987-09-21 | 1989-09-12 | Martha Hedberg | Suction stylet for endotracheal intubation |
CN88203061U (zh) | 1988-02-05 | 1988-11-23 | 黄传诗 | 脏器穿刺针 |
IT1234978B (it) | 1988-06-01 | 1992-06-09 | Tecres Spa | Miscela cementifera a due fasi, particolarmente adatta per usi ortopedici. |
US4961731A (en) | 1988-06-09 | 1990-10-09 | Sherwood Medical Company | Angiographic catheter with balanced dye injection openings |
US7431722B1 (en) | 1995-02-27 | 2008-10-07 | Warsaw Orthopedic, Inc. | Apparatus including a guard member having a passage with a non-circular cross section for providing protected access to the spine |
US5088991A (en) | 1988-07-14 | 1992-02-18 | Novoste Corporation | Fuseless soft tip angiographic catheter |
US4998923A (en) | 1988-08-11 | 1991-03-12 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US5156606A (en) | 1988-10-11 | 1992-10-20 | Zimmer, Inc. | Method and apparatus for removing pre-placed prosthetic joints and preparing for their replacement |
US5264214A (en) | 1988-11-21 | 1993-11-23 | Collagen Corporation | Composition for bone repair |
US5296026A (en) | 1988-12-02 | 1994-03-22 | Monroe Eugene A | Phosphate glass cement |
US4982730A (en) | 1988-12-21 | 1991-01-08 | Lewis Jr Royce C | Ultrasonic wound cleaning method and apparatus |
US4963151A (en) | 1988-12-28 | 1990-10-16 | Trustees Of The University Of Pennsylvania | Reinforced bone cement, method of production thereof and reinforcing fiber bundles therefor |
US5372587A (en) | 1989-01-09 | 1994-12-13 | Pilot Cariovascular Systems, Inc. | Steerable medical device |
US5480382A (en) | 1989-01-09 | 1996-01-02 | Pilot Cardiovascular Systems, Inc. | Steerable medical device |
US4969888A (en) | 1989-02-09 | 1990-11-13 | Arie Scholten | Surgical protocol for fixation of osteoporotic bone using inflatable device |
US4969870A (en) | 1989-06-07 | 1990-11-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions |
US5049137A (en) | 1989-09-08 | 1991-09-17 | Thompson Jeffrey E | Prepackaged syringe and catheter apparatus for deep administration of a fluid, and method of making same |
US4961730A (en) | 1989-09-29 | 1990-10-09 | Poncy George W | Hypodermic syringe with sliding cap |
JPH0358402U (zh) | 1989-10-13 | 1991-06-06 | ||
US5196201A (en) | 1989-10-20 | 1993-03-23 | Bioapatite Ab | Implant material composition, preparation thereof as well as uses thereof and implant product obtainable therefrom |
US5295980A (en) | 1989-10-30 | 1994-03-22 | Ersek Robert A | Multi-use cannula system |
US5059193A (en) | 1989-11-20 | 1991-10-22 | Spine-Tech, Inc. | Expandable spinal implant and surgical method |
US5116305A (en) | 1990-02-01 | 1992-05-26 | Abiomed, Inc. | Curved intra aortic balloon with non-folding inflated balloon membrane |
US5152744A (en) | 1990-02-07 | 1992-10-06 | Smith & Nephew Dyonics | Surgical instrument |
US5454365A (en) | 1990-11-05 | 1995-10-03 | Bonutti; Peter M. | Mechanically expandable arthroscopic retractors |
US5197971A (en) | 1990-03-02 | 1993-03-30 | Bonutti Peter M | Arthroscopic retractor and method of using the same |
US5092891A (en) | 1990-03-08 | 1992-03-03 | Kummer Frederick J | Cement plug for the medullary canal of a bone and coacting tool for installing same |
NL9000833A (nl) | 1990-04-09 | 1991-11-01 | Cordis Europ | Angiografie-catheter. |
US5266248A (en) | 1990-05-10 | 1993-11-30 | Torao Ohtsuka | Method of producing hydroxylapatite base porous beads filler for an organism |
US5103804A (en) | 1990-07-03 | 1992-04-14 | Boston Scientific Corporation | Expandable tip hemostatic probes and the like |
US6080801A (en) | 1990-09-13 | 2000-06-27 | Klaus Draenert | Multi-component material and process for its preparation |
ZA917281B (en) | 1990-09-26 | 1992-08-26 | Cryomedical Sciences Inc | Cryosurgical instrument and system and method of cryosurgery |
DE4033343A1 (de) | 1990-10-19 | 1992-04-23 | Draenert Klaus | Werkstoff als ausgangsmaterial zur herstellung von knochenzement und verfahren zu seiner herstellung |
US5147334A (en) | 1991-01-02 | 1992-09-15 | Moss James P | Catheter for cholangiography |
US5231989A (en) | 1991-02-15 | 1993-08-03 | Raychem Corporation | Steerable cannula |
AU660444B2 (en) | 1991-02-15 | 1995-06-29 | Ingemar H. Lundquist | Torquable catheter and method |
US5161715A (en) | 1991-03-25 | 1992-11-10 | Giannuzzi Anthony C | Double-barreled epoxy injection gun |
US5368598A (en) | 1991-04-19 | 1994-11-29 | Hasson; Harrith M. | Method of manipulating an uterus using a bendable manipulator |
US5188619A (en) | 1991-04-24 | 1993-02-23 | Gene E. Myers Enterprises, Inc. | Internal thoractic artery catheter |
US5112303A (en) | 1991-05-02 | 1992-05-12 | Pudenz-Schulte Medical Research Corporation | Tumor access device and method for delivering medication into a body cavity |
US5356629A (en) | 1991-07-12 | 1994-10-18 | United States Surgical Corporation | Composition for effecting bone repair |
US5211631A (en) | 1991-07-24 | 1993-05-18 | Sheaff Charles M | Patient warming apparatus |
US5308342A (en) | 1991-08-07 | 1994-05-03 | Target Therapeutics, Inc. | Variable stiffness catheter |
US5285795A (en) | 1991-09-12 | 1994-02-15 | Surgical Dynamics, Inc. | Percutaneous discectomy system having a bendable discectomy probe and a steerable cannula |
US5697281A (en) | 1991-10-09 | 1997-12-16 | Arthrocare Corporation | System and method for electrosurgical cutting and ablation |
US5697909A (en) | 1992-01-07 | 1997-12-16 | Arthrocare Corporation | Methods and apparatus for surgical cutting |
US5662680A (en) | 1991-10-18 | 1997-09-02 | Desai; Ashvin H. | Endoscopic surgical instrument |
US5681282A (en) | 1992-01-07 | 1997-10-28 | Arthrocare Corporation | Methods and apparatus for ablation of luminal tissues |
US5284128A (en) | 1992-01-24 | 1994-02-08 | Applied Medical Resources Corporation | Surgical manipulator |
US5336699A (en) | 1992-02-20 | 1994-08-09 | Orthopaedic Research Institute | Bone cement having chemically joined reinforcing fillers |
CA2128783C (en) | 1992-02-28 | 2004-10-12 | Donald G. Wallace | Injectable ceramic compositions and methods for their preparation and use |
US5269750A (en) | 1992-06-22 | 1993-12-14 | Stryker Corporation | Tip unit for fluid transfer surgical handpiece |
US5342299A (en) | 1992-07-06 | 1994-08-30 | Catheter Imaging Systems | Steerable catheter |
US5334626A (en) | 1992-07-28 | 1994-08-02 | Zimmer, Inc. | Bone cement composition and method of manufacture |
US5343877A (en) | 1992-09-09 | 1994-09-06 | University Of Iowa Research Foundation | Orthopedic implant and method |
US5380307A (en) | 1992-09-30 | 1995-01-10 | Target Therapeutics, Inc. | Catheter with atraumatic drug delivery tip |
US5549542A (en) | 1992-11-17 | 1996-08-27 | Life Medical Technologies, Inc. | Deflectable endoscope |
FR2697995B1 (fr) | 1992-11-19 | 1994-12-30 | Celsa Lg | Dispositif amovible de filtration sanguine, à rigidité variable, implantable dans le corps d'un patient et autorisant l'injection d'un produit traitant. |
US5389073A (en) | 1992-12-01 | 1995-02-14 | Cardiac Pathways Corporation | Steerable catheter with adjustable bend location |
US5342356A (en) | 1992-12-02 | 1994-08-30 | Ellman Alan G | Electrical coupling unit for electrosurgery |
US5282821A (en) | 1993-01-26 | 1994-02-01 | Donahue John R | Adjustable surgical instrument |
US5620447A (en) | 1993-01-29 | 1997-04-15 | Smith & Nephew Dyonics Inc. | Surgical instrument |
US5833692A (en) | 1993-01-29 | 1998-11-10 | Smith & Nephew, Inc. | Surgical instrument |
DE69433774T2 (de) | 1993-02-19 | 2005-04-14 | Boston Scientific Corp., Natick | Chirurgischer extraktor |
US5378234A (en) | 1993-03-15 | 1995-01-03 | Pilot Cardiovascular Systems, Inc. | Coil polymer composite |
US5766153A (en) | 1993-05-10 | 1998-06-16 | Arthrocare Corporation | Methods and apparatus for surgical cutting |
US5531715A (en) | 1993-05-12 | 1996-07-02 | Target Therapeutics, Inc. | Lubricious catheters |
US5628771A (en) | 1993-05-12 | 1997-05-13 | Olympus Optical Co., Ltd. | Electromagnetic-wave thermatological device |
JPH0751379A (ja) | 1993-06-24 | 1995-02-28 | Cardiovascular Dynamics Inc | 注入カテーテル及び脈管内部位処置方法並びにカテーテル製造方法 |
US5571088A (en) | 1993-07-01 | 1996-11-05 | Boston Scientific Corporation | Ablation catheters |
US5860974A (en) | 1993-07-01 | 1999-01-19 | Boston Scientific Corporation | Heart ablation catheter with expandable electrode and method of coupling energy to an electrode on a catheter shaft |
US5431639A (en) | 1993-08-12 | 1995-07-11 | Boston Scientific Corporation | Treating wounds caused by medical procedures |
US5616121A (en) | 1993-08-17 | 1997-04-01 | Mckay; Douglas W. | Method for alleviating pain in a wound |
US5431168A (en) | 1993-08-23 | 1995-07-11 | Cordis-Webster, Inc. | Steerable open-lumen catheter |
US5449351A (en) | 1993-09-09 | 1995-09-12 | Zohmann; Walter A. | Atraumatic needle for lumbar puncture |
US5385563A (en) | 1993-09-14 | 1995-01-31 | The Kendall Company | Urodynamic catheter |
US5360416A (en) | 1993-09-30 | 1994-11-01 | Sherwood Medical Company | Thin-walled anesthesia needles |
US6001093A (en) | 1993-10-15 | 1999-12-14 | Ep Technologies, Inc. | Systems and methods for creating long, thin lesions in body tissue |
WO1995010225A1 (en) | 1993-10-15 | 1995-04-20 | Ep Technologies, Inc. | Multiple electrode element for mapping and ablating |
US5458597A (en) | 1993-11-08 | 1995-10-17 | Zomed International | Device for treating cancer and non-malignant tumors and methods |
US5599346A (en) | 1993-11-08 | 1997-02-04 | Zomed International, Inc. | RF treatment system |
US5449301A (en) | 1993-11-17 | 1995-09-12 | Berg Technology, Inc. | Shunt connector |
US5514137A (en) | 1993-12-06 | 1996-05-07 | Coutts; Richard D. | Fixation of orthopedic devices |
US20060100635A1 (en) | 1994-01-26 | 2006-05-11 | Kyphon, Inc. | Inflatable device for use in surgical protocol relating to fixation of bone |
US20030032963A1 (en) | 2001-10-24 | 2003-02-13 | Kyphon Inc. | Devices and methods using an expandable body with internal restraint for compressing cancellous bone |
US6716216B1 (en) | 1998-08-14 | 2004-04-06 | Kyphon Inc. | Systems and methods for treating vertebral bodies |
US7166121B2 (en) | 1994-01-26 | 2007-01-23 | Kyphon Inc. | Systems and methods using expandable bodies to push apart cortical bone surfaces |
EP1464293B1 (en) | 1994-01-26 | 2007-05-02 | Kyphon Inc. | Improved inflatable device for use in surgical methods relating to fixation of bone |
US7044954B2 (en) | 1994-01-26 | 2006-05-16 | Kyphon Inc. | Method for treating a vertebral body |
US6241734B1 (en) | 1998-08-14 | 2001-06-05 | Kyphon, Inc. | Systems and methods for placing materials into bone |
US6248110B1 (en) | 1994-01-26 | 2001-06-19 | Kyphon, Inc. | Systems and methods for treating fractured or diseased bone using expandable bodies |
US5571189A (en) | 1994-05-20 | 1996-11-05 | Kuslich; Stephen D. | Expandable fabric implant for stabilizing the spinal motion segment |
US5514130A (en) | 1994-10-11 | 1996-05-07 | Dorsal Med International | RF apparatus for controlled depth ablation of soft tissue |
US5554114A (en) | 1994-10-20 | 1996-09-10 | Micro Therapeutics, Inc. | Infusion device with preformed shape |
US5858003A (en) | 1994-10-20 | 1999-01-12 | Children's Medical Center Corporation | Systems and methods for promoting tissue growth |
US5779688A (en) | 1994-10-28 | 1998-07-14 | Intella Interventional Systems, Inc. | Low profile balloon-on-a-wire catheter with shapeable and/or deflectable tip and method |
US5549637A (en) | 1994-11-10 | 1996-08-27 | Crainich; Lawrence | Articulated medical instrument |
US5489275A (en) | 1994-11-14 | 1996-02-06 | Ep Technologies, Inc. | Identification ring for catheter |
AU4242996A (en) | 1994-11-23 | 1996-06-17 | Navarre Biomedical, Ltd. | Flexible catheter |
US5535922A (en) | 1994-11-29 | 1996-07-16 | Tah Industries, Inc. | Caulking gun dispensing module for multi-component cartridge |
JP4255135B2 (ja) | 1995-01-04 | 2009-04-15 | アボット、カーディオバスキュラー、システムズ、インコーポレーテッド | 長円形状の横断面を備えたカテーテル軸 |
GB0102529D0 (en) | 2001-01-31 | 2001-03-21 | Thales Optronics Staines Ltd | Improvements relating to thermal imaging cameras |
US6291547B1 (en) | 1995-02-08 | 2001-09-18 | Materials Evolution And Development Usa Inc. | Bone cement compositions comprising fused fibrous compounds |
US6409722B1 (en) | 1998-07-07 | 2002-06-25 | Medtronic, Inc. | Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue |
US5947964A (en) | 1995-03-03 | 1999-09-07 | Neothermia Corporation | Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue |
US6312428B1 (en) | 1995-03-03 | 2001-11-06 | Neothermia Corporation | Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue |
US6106524A (en) | 1995-03-03 | 2000-08-22 | Neothermia Corporation | Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue |
US5571085A (en) | 1995-03-24 | 1996-11-05 | Electro-Catheter Corporation | Steerable open lumen catheter |
US6602248B1 (en) | 1995-06-07 | 2003-08-05 | Arthro Care Corp. | Methods for repairing damaged intervertebral discs |
US5741320A (en) | 1995-05-02 | 1998-04-21 | Heart Rhythm Technologies, Inc. | Catheter control system having a pulley |
US6575969B1 (en) | 1995-05-04 | 2003-06-10 | Sherwood Services Ag | Cool-tip radiofrequency thermosurgery electrode system for tumor ablation |
US7179255B2 (en) | 1995-06-07 | 2007-02-20 | Arthrocare Corporation | Methods for targeted electrosurgery on contained herniated discs |
US6280413B1 (en) | 1995-06-07 | 2001-08-28 | Medtronic Ave, Inc. | Thrombolytic filtration and drug delivery catheter with a self-expanding portion |
US5725568A (en) | 1995-06-27 | 1998-03-10 | Scimed Life Systems, Inc. | Method and device for recanalizing and grafting arteries |
AU6499596A (en) | 1995-07-18 | 1997-02-18 | Edwards, Garland U. | Flexible shaft |
US5681289A (en) | 1995-08-14 | 1997-10-28 | Medicinelodge Inc. | Chemical dispensing system |
US5810804A (en) | 1995-08-15 | 1998-09-22 | Rita Medical Systems | Multiple antenna ablation apparatus and method with cooling element |
US5637091A (en) | 1995-08-31 | 1997-06-10 | Hakky; Said I. | Collapsible catheter |
US5620467A (en) | 1995-10-10 | 1997-04-15 | Incontrol, Inc. | Implantable atrial defibrillator having cardioverting output voltage limiting for simulating larger storage capacitors |
AU726713B2 (en) | 1995-10-13 | 2000-11-16 | Transvascular, Inc. | Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures |
US5776193A (en) | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
US6283960B1 (en) | 1995-10-24 | 2001-09-04 | Oratec Interventions, Inc. | Apparatus for delivery of energy to a surgical site |
US5980504A (en) | 1996-08-13 | 1999-11-09 | Oratec Interventions, Inc. | Method for manipulating tissue of an intervertebral disc |
US5624396A (en) | 1995-10-30 | 1997-04-29 | Micro Therapeutics, Inc. | Longitudinally extendable infusion device |
US5709697A (en) | 1995-11-22 | 1998-01-20 | United States Surgical Corporation | Apparatus and method for removing tissue |
US7270661B2 (en) | 1995-11-22 | 2007-09-18 | Arthocare Corporation | Electrosurgical apparatus and methods for treatment and removal of tissue |
US20030069522A1 (en) | 1995-12-07 | 2003-04-10 | Jacobsen Stephen J. | Slotted medical device |
US5833632A (en) | 1995-12-07 | 1998-11-10 | Sarcos, Inc. | Hollow guide wire apparatus catheters |
US5860952A (en) | 1996-01-11 | 1999-01-19 | C. R. Bard, Inc. | Corporeal access tube assembly and method |
DE19604156A1 (de) | 1996-02-06 | 1997-08-07 | Boehringer Mannheim Gmbh | Schneidvorrichtung für Haut zur schmerzarmen Entnahme kleiner Blutmengen |
US5885258A (en) | 1996-02-23 | 1999-03-23 | Memory Medical Systems, Inc. | Medical instrument with slotted memory metal tube |
US6228052B1 (en) | 1996-02-29 | 2001-05-08 | Medtronic Inc. | Dilator for introducer system having injection port |
US5695513A (en) | 1996-03-01 | 1997-12-09 | Metagen, Llc | Flexible cutting tool and methods for its use |
US5735829A (en) | 1996-03-22 | 1998-04-07 | Cherian; George | Intercostal anesthetic infusion catheter |
US6110155A (en) | 1996-04-30 | 2000-08-29 | Medtronic, Inc. | Anti-inflammatory-agent-loaded catheter and method for preventing tissue fibrosis |
WO1997041924A1 (en) | 1996-05-06 | 1997-11-13 | Thermal Therapeutics, Inc. | Transcervical intrauterine applicator for intrauterine hyperthermia |
US5985659A (en) | 1996-05-21 | 1999-11-16 | The Institute Of Physical And Chemical Research | Embryonic stem cell lines obtained from C3H/HeN and DBA/1J mouse strains |
US5700157A (en) | 1996-06-05 | 1997-12-23 | D-Link Corporation | Electric jack with display means |
US5681317A (en) | 1996-06-12 | 1997-10-28 | Johnson & Johnson Professional, Inc. | Cement delivery system and method |
US6312454B1 (en) | 1996-06-13 | 2001-11-06 | Nitinol Devices & Components | Stent assembly |
US6136885A (en) | 1996-06-14 | 2000-10-24 | 3M Innovative Proprerties Company | Glass ionomer cement |
GB2314274A (en) | 1996-06-20 | 1997-12-24 | Gyrus Medical Ltd | Electrode construction for an electrosurgical instrument |
US6066176A (en) | 1996-07-11 | 2000-05-23 | Oshida; Yoshiki | Orthopedic implant system |
US7104986B2 (en) | 1996-07-16 | 2006-09-12 | Arthrocare Corporation | Intervertebral disc replacement method |
US6726684B1 (en) | 1996-07-16 | 2004-04-27 | Arthrocare Corporation | Methods for electrosurgical spine surgery |
US5820592A (en) | 1996-07-16 | 1998-10-13 | Hammerslag; Gary R. | Angiographic and/or guide catheter |
ATE260072T1 (de) | 1996-07-18 | 2004-03-15 | Implant Innovations Inc | Motorisch angetriebene osteotomiewerkzeuge zum verdichten von knochengewebe |
GB9616267D0 (en) | 1996-08-02 | 1996-09-11 | Ranier Ltd | Balloon catheter |
US6258086B1 (en) | 1996-10-23 | 2001-07-10 | Oratec Interventions, Inc. | Catheter for delivery of energy to a surgical site |
US6126682A (en) | 1996-08-13 | 2000-10-03 | Oratec Interventions, Inc. | Method for treating annular fissures in intervertebral discs |
US6280473B1 (en) | 1996-08-19 | 2001-08-28 | Macropore, Inc. | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
US5905000A (en) | 1996-09-03 | 1999-05-18 | Nanomaterials Research Corporation | Nanostructured ion conducting solid electrolytes |
US5855577A (en) * | 1996-09-17 | 1999-01-05 | Eclipse Surgical Technologies, Inc. | Bow shaped catheter |
US6953594B2 (en) | 1996-10-10 | 2005-10-11 | Etex Corporation | Method of preparing a poorly crystalline calcium phosphate and methods of its use |
US5891027A (en) | 1996-10-21 | 1999-04-06 | Irvine Biomedical, Inc. | Cardiovascular catheter system with an inflatable soft tip |
US7052493B2 (en) | 1996-10-22 | 2006-05-30 | Epicor Medical, Inc. | Methods and devices for ablation |
AU4996097A (en) | 1996-10-23 | 1998-05-15 | Oratec Interventions, Inc. | Method and apparatus for treating intervertebral discs |
US5800408A (en) | 1996-11-08 | 1998-09-01 | Micro Therapeutics, Inc. | Infusion device for distributing infusate along an elongated infusion segment |
US5902839A (en) | 1996-12-02 | 1999-05-11 | Northwestern University | Bone cement and method of preparation |
US5914356A (en) | 1996-12-06 | 1999-06-22 | Orthovita, Inc. | Bioactive load bearing bone bonding compositions |
US6332880B1 (en) | 1996-12-19 | 2001-12-25 | Ep Technologies, Inc. | Loop structures for supporting multiple electrode elements |
US6030360A (en) | 1996-12-30 | 2000-02-29 | Biggs; Robert C. | Steerable catheter |
US6146355A (en) | 1996-12-30 | 2000-11-14 | Myelotec, Inc. | Steerable catheter |
US6013591A (en) | 1997-01-16 | 2000-01-11 | Massachusetts Institute Of Technology | Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production |
US5931829A (en) | 1997-01-21 | 1999-08-03 | Vasca, Inc. | Methods and systems for establishing vascular access |
JP3527378B2 (ja) | 1997-01-31 | 2004-05-17 | テルモ株式会社 | 造影用カテーテル |
EP1006908A2 (en) | 1997-02-12 | 2000-06-14 | Oratec Interventions, Inc. | Concave probe for arthroscopic surgery |
US20060271061A1 (en) | 2001-07-25 | 2006-11-30 | Disc-O-Tech, Ltd. | Deformable tools and implants |
IL128261A0 (en) | 1999-01-27 | 1999-11-30 | Disc O Tech Medical Tech Ltd | Expandable element |
CA2283190A1 (en) | 1997-03-07 | 1998-09-11 | Mordechay Beyar | Systems for percutaneous bone and spinal stabilization, fixation and repair |
US5847046A (en) | 1997-03-12 | 1998-12-08 | United States Surgical Corporation | Biodegradable bone cement |
US6063078A (en) | 1997-03-12 | 2000-05-16 | Medtronic, Inc. | Method and apparatus for tissue ablation |
US5876373A (en) | 1997-04-04 | 1999-03-02 | Eclipse Surgical Technologies, Inc. | Steerable catheter |
US6524296B1 (en) | 1997-04-17 | 2003-02-25 | Medtronic, Inc. | Vessel cannula having properties varying along the axial length |
US6165166A (en) | 1997-04-25 | 2000-12-26 | Schneider (Usa) Inc. | Trilayer, extruded medical tubing and medical devices incorporating such tubing |
US5810867A (en) | 1997-04-28 | 1998-09-22 | Medtronic, Inc. | Dilatation catheter with varied stiffness |
US5849028A (en) | 1997-05-16 | 1998-12-15 | Irvine Biomedical, Inc. | Catheter and method for radiofrequency ablation of cardiac tissue |
US6428894B1 (en) | 1997-06-04 | 2002-08-06 | International Business Machines Corporation | Tunable and removable plasma deposited antireflective coatings |
US5972015A (en) | 1997-08-15 | 1999-10-26 | Kyphon Inc. | Expandable, asymetric structures for deployment in interior body regions |
US5851212A (en) | 1997-06-11 | 1998-12-22 | Endius Incorporated | Surgical instrument |
US20020077595A1 (en) | 1998-06-15 | 2002-06-20 | Ronald R Hundertmark | Endovascular coronary sinus catheter and method of use |
US6048346A (en) | 1997-08-13 | 2000-04-11 | Kyphon Inc. | Systems and methods for injecting flowable materials into bones |
US6645213B2 (en) | 1997-08-13 | 2003-11-11 | Kyphon Inc. | Systems and methods for injecting flowable materials into bones |
US5924976A (en) | 1997-08-21 | 1999-07-20 | Stelzer; Paul | Minimally invasive surgery device |
US5921956A (en) | 1997-09-24 | 1999-07-13 | Smith & Nephew, Inc. | Surgical instrument |
US6228079B1 (en) | 1997-10-06 | 2001-05-08 | Somnus Medical Technology, Inc. | Method and apparatus for power measurement in radio frequency electro-surgical generators |
US6309420B1 (en) | 1997-10-14 | 2001-10-30 | Parallax Medical, Inc. | Enhanced visibility materials for implantation in hard tissue |
JP4131508B2 (ja) | 1997-11-14 | 2008-08-13 | ボストン サイエンティフィック リミテッド | マルチ−シース送達カテーテル |
US6280441B1 (en) | 1997-12-15 | 2001-08-28 | Sherwood Services Ag | Apparatus and method for RF lesioning |
US5997581A (en) | 1997-12-29 | 1999-12-07 | Johnson & Johnson Professional, Inc. | Hip stem cement spacer |
US6251092B1 (en) | 1997-12-30 | 2001-06-26 | Medtronic, Inc. | Deflectable guiding catheter |
US20060074442A1 (en) | 2000-04-06 | 2006-04-06 | Revascular Therapeutics, Inc. | Guidewire for crossing occlusions or stenoses |
US5928239A (en) | 1998-03-16 | 1999-07-27 | University Of Washington | Percutaneous surgical cavitation device and method |
AU3203599A (en) | 1998-04-01 | 1999-10-18 | Parallax Medical, Inc. | Pressure applicator for hard tissue implant placement |
US7572263B2 (en) | 1998-04-01 | 2009-08-11 | Arthrocare Corporation | High pressure applicator |
US6440138B1 (en) | 1998-04-06 | 2002-08-27 | Kyphon Inc. | Structures and methods for creating cavities in interior body regions |
JP3360810B2 (ja) | 1998-04-14 | 2003-01-07 | ペンタックス株式会社 | 骨補填材の製造方法 |
US6106539A (en) | 1998-04-15 | 2000-08-22 | Neosurg Technologies | Trocar with removable, replaceable tip |
US6064902A (en) | 1998-04-16 | 2000-05-16 | C.R. Bard, Inc. | Pulmonary vein ablation catheter |
US6019765A (en) | 1998-05-06 | 2000-02-01 | Johnson & Johnson Professional, Inc. | Morsellized bone allograft applicator device |
US6059739A (en) | 1998-05-29 | 2000-05-09 | Medtronic, Inc. | Method and apparatus for deflecting a catheter or lead |
ATE484247T1 (de) | 1998-06-01 | 2010-10-15 | Kyphon S Rl | Entfaltbare, vorgeformte strukturen zur auffaltung in regionen innerhalb des körpers |
US6719773B1 (en) | 1998-06-01 | 2004-04-13 | Kyphon Inc. | Expandable structures for deployment in interior body regions |
US6706039B2 (en) | 1998-07-07 | 2004-03-16 | Medtronic, Inc. | Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue |
US6641587B2 (en) | 1998-08-14 | 2003-11-04 | Kyphon Inc. | Systems and methods for treating vertebral bodies |
US6123702A (en) | 1998-09-10 | 2000-09-26 | Scimed Life Systems, Inc. | Systems and methods for controlling power in an electrosurgical probe |
GB9820369D0 (en) | 1998-09-19 | 1998-11-11 | Giltech Ltd | Material |
US6544215B1 (en) | 1998-10-02 | 2003-04-08 | Scimed Life Systems, Inc. | Steerable device for introducing diagnostic and therapeutic apparatus into the body |
WO2000033909A1 (en) | 1998-12-09 | 2000-06-15 | Cook Incorporated | Hollow, curved, superelastic medical needle |
DE60017363T2 (de) | 1999-02-02 | 2006-03-02 | Wright Medical Technology Inc., Arlington | Kontrollierte freisetzung eines verbundmaterials |
EP1150725B1 (en) | 1999-02-04 | 2005-06-01 | SDGI Holdings, Inc. | Osteogenic paste compositions and uses thereof |
US6203507B1 (en) | 1999-03-03 | 2001-03-20 | Cordis Webster, Inc. | Deflectable catheter with ergonomic handle |
US6770079B2 (en) | 1999-03-16 | 2004-08-03 | American Osteomedix, Inc. | Apparatus and method for fixation of osteoporotic bone |
US6395007B1 (en) | 1999-03-16 | 2002-05-28 | American Osteomedix, Inc. | Apparatus and method for fixation of osteoporotic bone |
US6183435B1 (en) | 1999-03-22 | 2001-02-06 | Cordis Webster, Inc. | Multi-directional steerable catheters and control handles |
AU6168699A (en) | 1999-03-24 | 2000-10-09 | Parallax Medical, Inc. | Non-compliant system for delivery of implant material |
US6506217B1 (en) | 1999-03-29 | 2003-01-14 | Arnett Facial Reconstruction Courses, Inc. | Moldable post-implantation bone filler and method |
US6689823B1 (en) | 1999-03-31 | 2004-02-10 | The Brigham And Women's Hospital, Inc. | Nanocomposite surgical materials and method of producing them |
US20040044350A1 (en) | 1999-04-09 | 2004-03-04 | Evalve, Inc. | Steerable access sheath and methods of use |
US6270476B1 (en) | 1999-04-23 | 2001-08-07 | Cryocath Technologies, Inc. | Catheter |
US6352533B1 (en) | 1999-05-03 | 2002-03-05 | Alan G. Ellman | Electrosurgical handpiece for treating tissue |
US6582446B1 (en) | 1999-05-06 | 2003-06-24 | J. Alexander Marchosky | Method and apparatus for percutaneous osteoplasty |
US6478793B1 (en) | 1999-06-11 | 2002-11-12 | Sherwood Services Ag | Ablation treatment of bone metastases |
US6890329B2 (en) | 1999-06-15 | 2005-05-10 | Cryocath Technologies Inc. | Defined deflection structure |
US6479565B1 (en) | 1999-08-16 | 2002-11-12 | Harold R. Stanley | Bioactive ceramic cement |
US6783515B1 (en) | 1999-09-30 | 2004-08-31 | Arthrocare Corporation | High pressure delivery system |
JP4454078B2 (ja) | 1999-10-08 | 2010-04-21 | 株式会社町田製作所 | 内視鏡の湾曲管およびその製造方法 |
US7081122B1 (en) | 1999-10-19 | 2006-07-25 | Kyphon Inc. | Hand-held instruments that access interior body regions |
US6575919B1 (en) | 1999-10-19 | 2003-06-10 | Kyphon Inc. | Hand-held instruments that access interior body regions |
US7641657B2 (en) | 2003-06-10 | 2010-01-05 | Trans1, Inc. | Method and apparatus for providing posterior or anterior trans-sacral access to spinal vertebrae |
US6241710B1 (en) | 1999-12-20 | 2001-06-05 | Tricardia Llc | Hypodermic needle with weeping tip and method of use |
US6599961B1 (en) | 2000-02-01 | 2003-07-29 | University Of Kentucky Research Foundation | Polymethylmethacrylate augmented with carbon nanotubes |
US6383188B2 (en) | 2000-02-15 | 2002-05-07 | The Spineology Group Llc | Expandable reamer |
US7014633B2 (en) | 2000-02-16 | 2006-03-21 | Trans1, Inc. | Methods of performing procedures in the spine |
US6790210B1 (en) | 2000-02-16 | 2004-09-14 | Trans1, Inc. | Methods and apparatus for forming curved axial bores through spinal vertebrae |
US6740093B2 (en) | 2000-02-28 | 2004-05-25 | Stephen Hochschuler | Method and apparatus for treating a vertebral body |
US6332894B1 (en) | 2000-03-07 | 2001-12-25 | Zimmer, Inc. | Polymer filled spinal fusion cage |
US6447514B1 (en) | 2000-03-07 | 2002-09-10 | Zimmer | Polymer filled hip fracture fixation device |
US6358251B1 (en) | 2000-03-21 | 2002-03-19 | University Of Washington | Method and apparatus for forming a cavity in soft tissue or bone |
WO2001074252A2 (en) | 2000-03-31 | 2001-10-11 | Rita Medical Systems Inc. | Tissue biopsy and treatment apparatus and method |
DE60121556T2 (de) | 2000-04-05 | 2007-06-28 | Pathway Medical Technologies, Inc., Redmond | System und Verfahren zum Entfernen von intraluminalem Material |
ATE318559T1 (de) | 2000-04-05 | 2006-03-15 | Kyphon Inc | Vorrichtungen zur behandlung von gebrochenen und/oder erkrankten knochen |
US6565588B1 (en) | 2000-04-05 | 2003-05-20 | Pathway Medical Technologies, Inc. | Intralumenal material removal using an expandable cutting device |
US6638268B2 (en) | 2000-04-07 | 2003-10-28 | Imran K. Niazi | Catheter to cannulate the coronary sinus |
EP1272113B1 (en) | 2000-04-07 | 2012-03-21 | Kyphon SÀRL | Insertion devices |
US7815649B2 (en) | 2000-04-07 | 2010-10-19 | Kyphon SÀRL | Insertion devices and method of use |
US6869445B1 (en) | 2000-05-04 | 2005-03-22 | Phillips Plastics Corp. | Packable ceramic beads for bone repair |
US6743239B1 (en) | 2000-05-25 | 2004-06-01 | St. Jude Medical, Inc. | Devices with a bendable tip for medical procedures |
ATE308933T1 (de) | 2000-06-23 | 2005-11-15 | Cryocath Technologies Inc | Vorrichtung zur kryobehandlung |
GB0016516D0 (en) | 2000-07-06 | 2000-08-23 | Owen Mumford Ltd | Improvements relating to needle protection devices |
FR2811538B1 (fr) | 2000-07-12 | 2003-02-07 | Spine Next Sa | Outil de curetage intervertebral |
DE60141653D1 (de) | 2000-07-21 | 2010-05-06 | Spineology Group Llc | Eine dehnbare, poröse netzbeutel-vorrichtung und seine nutzung in der knochenchirugie |
EP1309280A2 (en) | 2000-08-11 | 2003-05-14 | SDGI Holdings, Inc. | Surgical instrumentation and method for treatment of the spine |
US7114501B2 (en) | 2000-08-14 | 2006-10-03 | Spine Wave, Inc. | Transverse cavity device and method |
US6669692B1 (en) | 2000-08-21 | 2003-12-30 | Biosense Webster, Inc. | Ablation catheter with cooled linear electrode |
US6679886B2 (en) | 2000-09-01 | 2004-01-20 | Synthes (Usa) | Tools and methods for creating cavities in bone |
AU1331302A (en) | 2000-10-16 | 2002-04-29 | Univ South Carolina Res Found | Biocompatible cement containing reactive calcium phosphate nanoparticles and methods for making and using such cement |
US20020068929A1 (en) | 2000-10-24 | 2002-06-06 | Roni Zvuloni | Apparatus and method for compressing a gas, and cryosurgery system and method utilizing same |
DE60140558D1 (de) | 2000-10-25 | 2009-12-31 | Kyphon S A R L | Systeme zur reposition von gebrochenen knochen mittels einer kanüle zur reponierung von knochenfrakturen |
US6916306B1 (en) | 2000-11-10 | 2005-07-12 | Boston Scientific Scimed, Inc. | Steerable loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
US6576249B1 (en) | 2000-11-13 | 2003-06-10 | El Gendler | Bone putty and method |
US20040087936A1 (en) | 2000-11-16 | 2004-05-06 | Barrx, Inc. | System and method for treating abnormal tissue in an organ having a layered tissue structure |
US6511471B2 (en) | 2000-12-22 | 2003-01-28 | Biocardia, Inc. | Drug delivery catheters that attach to tissue and methods for their use |
EP1363700A4 (en) | 2001-01-11 | 2005-11-09 | Rita Medical Systems Inc | INSTRUMENT AND METHOD FOR BONE TREATMENT |
US7008433B2 (en) | 2001-02-15 | 2006-03-07 | Depuy Acromed, Inc. | Vertebroplasty injection device |
US6648880B2 (en) | 2001-02-16 | 2003-11-18 | Cryocath Technologies Inc. | Method of using cryotreatment to treat brain tissue |
US7544196B2 (en) | 2001-02-20 | 2009-06-09 | Orthovita, Inc. | System and kit for delivery of restorative materials |
US6375659B1 (en) | 2001-02-20 | 2002-04-23 | Vita Licensing, Inc. | Method for delivery of biocompatible material |
DE10108261B4 (de) | 2001-02-21 | 2006-07-20 | Ivoclar Vivadent Ag | Polymerisierbare Zusammensetzung mit Füllstoff auf der Basis von partikulärem Komposit |
US20020115742A1 (en) | 2001-02-22 | 2002-08-22 | Trieu Hai H. | Bioactive nanocomposites and methods for their use |
CN1162187C (zh) | 2001-02-22 | 2004-08-18 | 华东理工大学 | 无机骨粘合剂及其在人体硬组织修复中的应用 |
US6623448B2 (en) | 2001-03-30 | 2003-09-23 | Advanced Cardiovascular Systems, Inc. | Steerable drug delivery device |
US6575978B2 (en) | 2001-04-05 | 2003-06-10 | Spineology, Inc. | Circumferential resecting reamer tool |
US6979312B2 (en) | 2001-04-12 | 2005-12-27 | Biotran Corporation, Inc. | Steerable sheath catheters |
US6837867B2 (en) | 2001-04-30 | 2005-01-04 | Biosense Webster, Inc. | Steerable catheter with reinforced tip |
US6610058B2 (en) | 2001-05-02 | 2003-08-26 | Cardiac Pacemakers, Inc. | Dual-profile steerable catheter |
JP4252316B2 (ja) | 2001-05-10 | 2009-04-08 | リタ メディカル システムズ インコーポレイテッド | Rf組織切除装置および方法 |
US6484904B1 (en) | 2001-05-21 | 2002-11-26 | Tah Industries, Inc. | Two-component cartridge system |
ITVI20010126A1 (it) | 2001-05-30 | 2002-11-30 | Tecres Spa | Cemento osseo radiopaco per uso ortopedico nonche' metodo di realizzazione |
US6746451B2 (en) | 2001-06-01 | 2004-06-08 | Lance M. Middleton | Tissue cavitation device and method |
US20020188300A1 (en) | 2001-06-06 | 2002-12-12 | Arramon Yves P. | Cannula system for hard tissue implant delivery |
DE10129842C1 (de) | 2001-06-15 | 2003-04-24 | Bam Bundesanstalt Matforschung | Verfahren zur Herstellung eines bioaktiven Knochenzements und Knochenzement-Kit |
US6814734B2 (en) | 2001-06-18 | 2004-11-09 | Sdgi Holdings, Inc, | Surgical instrumentation and method for forming a passage in bone having an enlarged cross-sectional portion |
NL1018438C1 (nl) | 2001-07-02 | 2003-01-08 | Baat Medical Engineering B V | In- en uitklapbaar gereedschap voor plaatsing in een ruggenwervel. |
US6835193B2 (en) | 2001-07-10 | 2004-12-28 | Myocardial Therapeutics, Inc. | Methods for controlled depth injections into interior body cavities |
US6679906B2 (en) | 2001-07-13 | 2004-01-20 | Radiant Medical, Inc. | Catheter system with on-board temperature probe |
US6620162B2 (en) | 2001-07-20 | 2003-09-16 | Spineology, Inc. | Device for inserting fill material particles into body cavities |
US7077842B1 (en) | 2001-08-03 | 2006-07-18 | Cosman Jr Eric R | Over-the-wire high frequency electrode |
WO2003013642A1 (fr) | 2001-08-08 | 2003-02-20 | Kaneka Corporation | Catheter a expansion |
JP3603278B2 (ja) | 2001-09-06 | 2004-12-22 | 理学電機工業株式会社 | 蛍光x線分析システムおよびそれに用いるプログラム |
US20030050644A1 (en) | 2001-09-11 | 2003-03-13 | Boucher Ryan P. | Systems and methods for accessing and treating diseased or fractured bone employing a guide wire |
US6893431B2 (en) | 2001-10-15 | 2005-05-17 | Scimed Life Systems, Inc. | Medical device for delivering patches |
GB0124742D0 (en) | 2001-10-16 | 2001-12-05 | Biocomposites Ltd | Biodegradable materials |
EP1448089A4 (en) | 2001-11-01 | 2008-06-04 | Spine Wave Inc | DEVICES AND METHODS FOR SPINACH RECOVERY |
US6913594B2 (en) | 2001-12-31 | 2005-07-05 | Biosense Webster, Inc. | Dual-function catheter handle |
GB0200610D0 (en) | 2002-01-11 | 2002-02-27 | Univ Aberdeen | Cladding |
US20030163085A1 (en) | 2002-01-16 | 2003-08-28 | Tanner Howard M. | Catheter hand-piece apparatus and method of using the same |
US6955716B2 (en) | 2002-03-01 | 2005-10-18 | American Dental Association Foundation | Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates |
US6896675B2 (en) | 2002-03-05 | 2005-05-24 | Baylis Medical Company Inc. | Intradiscal lesioning device |
US8882755B2 (en) | 2002-03-05 | 2014-11-11 | Kimberly-Clark Inc. | Electrosurgical device for treatment of tissue |
US8518036B2 (en) | 2002-03-05 | 2013-08-27 | Kimberly-Clark Inc. | Electrosurgical tissue treatment method |
US7294127B2 (en) | 2002-03-05 | 2007-11-13 | Baylis Medical Company Inc. | Electrosurgical tissue treatment method |
SE0201052D0 (sv) | 2002-04-04 | 2002-04-04 | Cerbio Tech Ab | Biocompatible cement compositions and method of manufacturing |
SI1366774T1 (sl) | 2002-05-29 | 2007-12-31 | Heraeus Kulzer Gmbh | Zmes za kostni cement in rentgensko kontrastno sredstvo |
US20030225432A1 (en) | 2002-05-31 | 2003-12-04 | Baptiste Reginald C. | Soft tissue retraction device for an endoscopic instrument |
WO2003101308A1 (en) | 2002-06-04 | 2003-12-11 | Office Of Technology Licensing Stanford University | Device and method for rapid aspiration and collection of body tissue from within an enclosed body space |
US7166133B2 (en) | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US20040023384A1 (en) | 2002-07-31 | 2004-02-05 | Isis Pharmaceuticals Inc. | Antisense modulation of G protein-coupled receptor 12 expression |
US7029468B2 (en) | 2002-06-25 | 2006-04-18 | Enpath Medical, Inc. | Catheter assembly with side wall exit lumen and method therefor |
US6730095B2 (en) | 2002-06-26 | 2004-05-04 | Scimed Life Systems, Inc. | Retrograde plunger delivery system |
KR100465985B1 (ko) | 2002-07-30 | 2005-01-15 | 재단법인서울대학교산학협력재단 | 인공골용 생체활성 복합 세라믹스 조성물 및 그의 제조방법 |
US7901407B2 (en) | 2002-08-02 | 2011-03-08 | Boston Scientific Scimed, Inc. | Media delivery device for bone structures |
US7393350B2 (en) | 2002-08-06 | 2008-07-01 | Erbe Elektromedizin Gmbh | Cryo-surgical apparatus and methods |
US20040087994A1 (en) | 2002-08-29 | 2004-05-06 | Loubert Suddaby | Mechanical bone tamping device for repair of osteoporotic bone fractures |
US7138442B2 (en) | 2002-08-30 | 2006-11-21 | Biomet, Inc. | Reduced exothermic bone replacement cement |
US8808284B2 (en) | 2008-09-26 | 2014-08-19 | Relievant Medsystems, Inc. | Systems for navigating an instrument through bone |
US8361067B2 (en) | 2002-09-30 | 2013-01-29 | Relievant Medsystems, Inc. | Methods of therapeutically heating a vertebral body to treat back pain |
US6907884B2 (en) | 2002-09-30 | 2005-06-21 | Depay Acromed, Inc. | Method of straddling an intraosseous nerve |
US8613744B2 (en) | 2002-09-30 | 2013-12-24 | Relievant Medsystems, Inc. | Systems and methods for navigating an instrument through bone |
US7066942B2 (en) | 2002-10-03 | 2006-06-27 | Wright Medical Technology, Inc. | Bendable needle for delivering bone graft material and method of use |
US7582309B2 (en) | 2002-11-15 | 2009-09-01 | Etex Corporation | Cohesive demineralized bone compositions |
AU2003290806A1 (en) | 2002-11-15 | 2004-06-15 | The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Variable curve catheter |
US6979352B2 (en) | 2002-11-21 | 2005-12-27 | Depuy Acromed | Methods of performing embolism-free vertebroplasty and devices therefor |
US20050251267A1 (en) | 2004-05-04 | 2005-11-10 | John Winterbottom | Cell permeable structural implant |
US6945956B2 (en) | 2002-12-23 | 2005-09-20 | Medtronic, Inc. | Steerable catheter |
SE524494C2 (sv) | 2002-12-31 | 2004-08-17 | Doxa Ab | Kemiskt bundna biomaterialelement med skräddarsydda egenskaper |
US20060024348A1 (en) | 2002-12-31 | 2006-02-02 | Doxa Aktiebolag | Chemically bonded biomaterial element with tailored properties |
US7390298B2 (en) | 2003-01-06 | 2008-06-24 | City Of Hope | Expandable surgical retractor for internal body spaces approached with minimally invasive incisions or through existing orifices |
US20040158237A1 (en) | 2003-02-11 | 2004-08-12 | Marwan Abboud | Multi-energy ablation station |
ATE336270T1 (de) | 2003-02-13 | 2006-09-15 | Synthes Ag | Injizierbare knochenersatzmischung |
JP2004242936A (ja) | 2003-02-14 | 2004-09-02 | Terumo Corp | 穿刺針 |
US6875219B2 (en) | 2003-02-14 | 2005-04-05 | Yves P. Arramon | Bone access system |
BRPI0407142A (pt) | 2003-02-14 | 2006-01-10 | Depuy Spine Inc | Dispositivo de fusão intervertebral formado in situ |
GB0307834D0 (en) | 2003-04-04 | 2003-05-14 | Ta Contrast Ab | Composition |
US20060206116A1 (en) | 2003-05-07 | 2006-09-14 | Yeung Jeffrey E | Injection device for the invertebral disc |
US7625364B2 (en) | 2003-05-27 | 2009-12-01 | Cardia, Inc. | Flexible center connection for occlusion device |
CN102201196B (zh) | 2003-06-06 | 2014-03-26 | 株式会社半导体能源研究所 | 半导体装置 |
US7112205B2 (en) | 2003-06-17 | 2006-09-26 | Boston Scientific Scimed, Inc. | Apparatus and methods for delivering compounds into vertebrae for vertebroplasty |
US8415407B2 (en) | 2004-03-21 | 2013-04-09 | Depuy Spine, Inc. | Methods, materials, and apparatus for treating bone and other tissue |
CA2533020A1 (en) | 2003-07-18 | 2005-03-03 | Ev3 Santa Rosa, Inc. | Remotely activated mitral annuloplasty system and methods |
US7887557B2 (en) | 2003-08-14 | 2011-02-15 | Boston Scientific Scimed, Inc. | Catheter having a cutting balloon including multiple cavities or multiple channels |
US20050240193A1 (en) | 2003-09-03 | 2005-10-27 | Kyphon Inc. | Devices for creating voids in interior body regions and related methods |
US7824412B2 (en) | 2003-09-05 | 2010-11-02 | Medical Design Instruments LLC | Cement/biologics inserter and method for bone-fastener fixation augmentation |
US7156843B2 (en) | 2003-09-08 | 2007-01-02 | Medtronic, Inc. | Irrigated focal ablation tip |
DE20314010U1 (de) | 2003-09-08 | 2005-01-13 | Witte, Peter | Drehmomentbegrenzer |
US8579908B2 (en) | 2003-09-26 | 2013-11-12 | DePuy Synthes Products, LLC. | Device for delivering viscous material |
US7094202B2 (en) | 2003-09-29 | 2006-08-22 | Ethicon Endo-Surgery, Inc. | Method of operating an endoscopic device with one hand |
US7909833B2 (en) | 2003-09-29 | 2011-03-22 | Depuy Acromed, Inc. | Vertebroplasty device having a flexible plunger |
US7998112B2 (en) | 2003-09-30 | 2011-08-16 | Abbott Cardiovascular Systems Inc. | Deflectable catheter assembly and method of making same |
US7708733B2 (en) | 2003-10-20 | 2010-05-04 | Arthrocare Corporation | Electrosurgical method and apparatus for removing tissue within a bone body |
AU2003293699A1 (en) | 2003-11-18 | 2005-06-17 | Somatex Medical Technologies Gmbh | Injection pump |
US20050113836A1 (en) | 2003-11-25 | 2005-05-26 | Lozier Antony J. | Expandable reamer |
DE602004006442T2 (de) | 2003-12-01 | 2008-01-10 | Broockeville Corp. N.V., Willemstad | Zweikomponentenmisch- und -ausgabevorrichtung |
US8221424B2 (en) | 2004-12-20 | 2012-07-17 | Spinascope, Inc. | Surgical instrument for orthopedic surgery |
US7727232B1 (en) | 2004-02-04 | 2010-06-01 | Salient Surgical Technologies, Inc. | Fluid-assisted medical devices and methods |
US7351280B2 (en) | 2004-02-10 | 2008-04-01 | New York University | Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment |
US7488322B2 (en) | 2004-02-11 | 2009-02-10 | Medtronic, Inc. | High speed surgical cutting instrument |
US7641664B2 (en) | 2004-02-12 | 2010-01-05 | Warsaw Orthopedic, Inc. | Surgical instrumentation and method for treatment of a spinal structure |
US20060064101A1 (en) | 2004-02-12 | 2006-03-23 | Arthrocare Corporation | Bone access system |
US20050187556A1 (en) | 2004-02-25 | 2005-08-25 | Synecor, Llc | Universal percutaneous spinal access system |
JP4879159B2 (ja) | 2004-03-05 | 2012-02-22 | アプライド マテリアルズ インコーポレイテッド | アモルファス炭素膜堆積のためのcvdプロセス |
US7959634B2 (en) | 2004-03-29 | 2011-06-14 | Soteira Inc. | Orthopedic surgery access devices |
US7507241B2 (en) | 2004-04-05 | 2009-03-24 | Expanding Orthopedics Inc. | Expandable bone device |
US7465318B2 (en) | 2004-04-15 | 2008-12-16 | Soteira, Inc. | Cement-directing orthopedic implants |
US7452351B2 (en) | 2004-04-16 | 2008-11-18 | Kyphon Sarl | Spinal diagnostic methods and apparatus |
US9554691B2 (en) | 2004-04-21 | 2017-01-31 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US8163030B2 (en) | 2004-05-06 | 2012-04-24 | Degradable Solutions Ag | Biocompatible bone implant compositions and methods for repairing a bone defect |
WO2005110259A1 (en) | 2004-05-19 | 2005-11-24 | Sintea Biotech S.P.A. | Intravertebral widening device, injection device, and kit and method for kyphoplasty |
WO2005122938A1 (en) | 2004-06-10 | 2005-12-29 | Arthrocare Corporation | Electrosurgical method and apparatus for removing tissue within a bone body |
EP1773205A2 (en) | 2004-06-16 | 2007-04-18 | Warsaw Orthopedic, Inc. | Surgical instrumentation for the repair of vertebral bodies |
US20050283148A1 (en) | 2004-06-17 | 2005-12-22 | Janssen William M | Ablation apparatus and system to limit nerve conduction |
CA2575699C (en) | 2004-07-30 | 2014-07-08 | Disc-O-Tech Medical Technologies Ltd. | Methods, materials and apparatus for treating bone and other tissue |
US20060085009A1 (en) | 2004-08-09 | 2006-04-20 | Csaba Truckai | Implants and methods for treating bone |
US7503920B2 (en) | 2004-08-11 | 2009-03-17 | Tzony Siegal | Spinal surgery system and method |
US20080319445A9 (en) | 2004-08-17 | 2008-12-25 | Scimed Life Systems, Inc. | Apparatus and methods for delivering compounds into vertebrae for vertebroplasty |
US20060106459A1 (en) | 2004-08-30 | 2006-05-18 | Csaba Truckai | Bone treatment systems and methods |
US7396360B2 (en) | 2004-09-29 | 2008-07-08 | The Cleveland Clinic Foundation | Minimally invasive method and apparatus for fusing adjacent vertebrae |
US20080015664A1 (en) | 2004-10-06 | 2008-01-17 | Podhajsky Ronald J | Systems and methods for thermally profiling radiofrequency electrodes |
US7559932B2 (en) | 2004-12-06 | 2009-07-14 | Dfine, Inc. | Bone treatment systems and methods |
US7682378B2 (en) | 2004-11-10 | 2010-03-23 | Dfine, Inc. | Bone treatment systems and methods for introducing an abrading structure to abrade bone |
US20060100706A1 (en) | 2004-11-10 | 2006-05-11 | Shadduck John H | Stent systems and methods for spine treatment |
US8663225B2 (en) | 2004-11-12 | 2014-03-04 | Medtronic, Inc. | Hydrogel bone void filler |
US8562607B2 (en) | 2004-11-19 | 2013-10-22 | Dfine, Inc. | Bone treatment systems and methods |
US8583260B2 (en) | 2004-12-28 | 2013-11-12 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Long travel steerable catheter actuator |
DE102005025946A1 (de) | 2005-01-26 | 2006-08-03 | Erbe Elektromedizin Gmbh | HF-Chirurgieeinrichtung |
GB0502384D0 (en) | 2005-02-04 | 2005-03-16 | Instrumedical Ltd | Electro-surgical needle apparatus |
US20060184192A1 (en) | 2005-02-11 | 2006-08-17 | Markworth Aaron D | Systems and methods for providing cavities in interior body regions |
US7959601B2 (en) | 2005-02-14 | 2011-06-14 | Biosense Webster, Inc. | Steerable catheter with in-plane deflection |
US20060200121A1 (en) | 2005-03-03 | 2006-09-07 | Mowery Thomas M | Navigable, multi-positional and variable tissue ablation apparatus and methods |
JP2006263184A (ja) | 2005-03-24 | 2006-10-05 | Gc Corp | 骨セメント注入充填方法及び骨セメント注入充填用漏洩防止袋 |
US7497853B2 (en) | 2005-05-05 | 2009-03-03 | Enpath Medical Inc. | Deflectable catheter steering and locking system |
US20070016130A1 (en) | 2005-05-06 | 2007-01-18 | Leeflang Stephen A | Complex Shaped Steerable Catheters and Methods for Making and Using Them |
US7442190B2 (en) | 2005-05-13 | 2008-10-28 | Cryocath Technologies Inc. | Contact assessment of balloon catheters |
US8187327B2 (en) | 2005-05-18 | 2012-05-29 | Kyphon Sarl | Selectively-expandable bone scaffold |
WO2006127904A1 (en) | 2005-05-24 | 2006-11-30 | Gary Botimer | Expandable surgical reaming tool |
US20060276797A1 (en) | 2005-05-24 | 2006-12-07 | Gary Botimer | Expandable reaming device |
AU2006249799A1 (en) | 2005-05-26 | 2006-11-30 | Smith & Nephew, Inc. | Electrothermal intervertebral disc treatment |
US20060293687A1 (en) | 2005-06-07 | 2006-12-28 | Bogert Roy B | Syringe plunger seal |
US20070010845A1 (en) | 2005-07-08 | 2007-01-11 | Gorman Gong | Directionally controlled expandable device and methods for use |
US20070055201A1 (en) | 2005-07-11 | 2007-03-08 | Seto Christine L | Systems and methods for providing cavities in interior body regions |
US20070006692A1 (en) | 2005-07-11 | 2007-01-11 | Phan Christopher U | Torque limiting device |
US8021366B2 (en) | 2005-07-11 | 2011-09-20 | Kyphon Sarl | Axial load limiting system and methods |
US7794458B2 (en) | 2005-07-22 | 2010-09-14 | Boston Scientific Scimed, Inc. | Bipolar radio frequency ablation device with retractable insulator |
EP2705809B1 (en) | 2005-08-16 | 2016-03-23 | Benvenue Medical, Inc. | Spinal tissue distraction devices |
CN2841051Y (zh) | 2005-08-24 | 2006-11-29 | 汤枧根 | 伞形治疗电极 |
US20070067034A1 (en) | 2005-08-31 | 2007-03-22 | Chirico Paul E | Implantable devices and methods for treating micro-architecture deterioration of bone tissue |
US20070118144A1 (en) | 2005-09-01 | 2007-05-24 | Csaba Truckai | Systems for sensing retrograde flows of bone fill material |
CN103349793B (zh) | 2005-09-09 | 2016-02-10 | 阿格诺沃斯健康关爱公司 | 复合骨移植替代物水泥以及由其制得的制品 |
US20070093840A1 (en) | 2005-10-06 | 2007-04-26 | Pacelli Nicolas J | Flexible shaft |
WO2007055521A1 (en) | 2005-11-09 | 2007-05-18 | Korea University Industrial & Academic Collaboration Foundation | Radio frequency ablation electrode for selected tissue removal |
US7823753B2 (en) | 2005-11-18 | 2010-11-02 | Kovac Karen S | Double barrel caulking gun caddy |
US7713273B2 (en) | 2005-11-18 | 2010-05-11 | Carefusion 2200, Inc. | Device, system and method for delivering a curable material into bone |
US7799035B2 (en) | 2005-11-18 | 2010-09-21 | Carefusion 2200, Inc. | Device, system and method for delivering a curable material into bone |
WO2007078692A2 (en) | 2005-12-23 | 2007-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for fixation of bone with an expandable device |
US7993334B2 (en) | 2005-12-29 | 2011-08-09 | Boston Scientific Scimed, Inc. | Low-profile, expanding single needle ablation probe |
US20070185231A1 (en) | 2006-01-23 | 2007-08-09 | Liu Y K | Bone cement composite containing particles in a non-uniform spatial distribution and devices for implementation |
US9301792B2 (en) | 2006-01-27 | 2016-04-05 | Stryker Corporation | Low pressure delivery system and method for delivering a solid and liquid mixture into a target site for medical treatment |
US20070203500A1 (en) | 2006-02-28 | 2007-08-30 | Vermillion Technologies, Llc | Apparatus and method of shaping an intervertebral space |
US7976542B1 (en) | 2006-03-02 | 2011-07-12 | Cosman Eric R | Adjustable high frequency electrode |
US20070270876A1 (en) | 2006-04-07 | 2007-11-22 | Yi-Chen Kuo | Vertebra bone cement introduction system |
US7905884B2 (en) | 2006-04-27 | 2011-03-15 | Warsaw Orthopedic, Inc. | Method for use of dilating stylet and cannula |
US7615044B2 (en) | 2006-05-03 | 2009-11-10 | Greatbatch Ltd. | Deflectable sheath handle assembly and method therefor |
US8075556B2 (en) | 2006-05-23 | 2011-12-13 | Andres Betts | High frequency epidural neuromodulation catheter for effectuating RF treatment in spinal canal and method of using same |
US20080033422A1 (en) | 2006-08-04 | 2008-02-07 | Turner Paul F | Microwave applicator with margin temperature sensing element |
US20080058840A1 (en) | 2006-09-01 | 2008-03-06 | Albrecht Thomas E | Implantable coil for insertion into a hollow body organ |
WO2008045212A2 (en) | 2006-10-06 | 2008-04-17 | Kyphon Sarl | Products and methods for percutaneous material delivery |
AU2007231733B2 (en) | 2006-11-28 | 2014-03-13 | Cathrx Ltd | A catheter steering system |
WO2008076330A1 (en) | 2006-12-15 | 2008-06-26 | Soteira, Inc. | Drills and methods for vertebrostenting |
EP2099390A2 (en) | 2007-01-09 | 2009-09-16 | Nonlinear Technologies Ltd. | Devices for forming curved or closed-loop structures |
US20080183265A1 (en) | 2007-01-30 | 2008-07-31 | Cardiac Pacemakers, Inc. | Transvascular lead with proximal force relief |
US8211099B2 (en) | 2007-01-31 | 2012-07-03 | Tyco Healthcare Group Lp | Thermal feedback systems and methods of using the same |
US8114084B2 (en) | 2007-03-07 | 2012-02-14 | Vertech, Inc. | Expandable blade device for stabilizing compression fractures |
EP2155084B1 (en) | 2007-04-03 | 2013-11-27 | Dfine, Inc. | Bone treatment systems |
US20080269766A1 (en) | 2007-04-30 | 2008-10-30 | Warsaw Orthopedic, Inc. | Intravertebral reduction device with retention balls |
ES2627667T3 (es) | 2007-05-18 | 2017-07-31 | Boston Scientific Limited | Dispositivo hueco de articulación que se puede torcer |
EP2164405A2 (en) | 2007-05-21 | 2010-03-24 | AOI Medical Inc. | Articulating cavitation device |
EP2211981A1 (en) | 2007-10-09 | 2010-08-04 | Boston Scientific Limited | Electrophysiology electrodes and apparatus including the same |
US20090105775A1 (en) | 2007-10-19 | 2009-04-23 | David Mitchell | Cannula with lateral access and directional exit port |
US20090131950A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Vertebroplasty method with enhanced control |
WO2011066465A1 (en) | 2009-11-25 | 2011-06-03 | Osseon Therapeutics, Inc. | Steerable and curvable vertebroplasty system with clog-resistant exit ports |
US20090131867A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Steerable vertebroplasty system with cavity creation element |
US20090299282A1 (en) | 2007-11-16 | 2009-12-03 | Osseon Therapeutics, Inc. | Steerable vertebroplasty system with a plurality of cavity creation elements |
US9510885B2 (en) | 2007-11-16 | 2016-12-06 | Osseon Llc | Steerable and curvable cavity creation system |
US20090131886A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Steerable vertebroplasty system |
US8961571B2 (en) | 2007-11-19 | 2015-02-24 | David Lee | Method and apparatus for spinal facet joint fusion using irregularly shaped cortical bone implants |
WO2009073209A1 (en) | 2007-12-06 | 2009-06-11 | Osseon Therapeutics, Inc. | Vertebroplasty implant with enhanced interfacial shear strength |
US8353902B2 (en) | 2008-01-31 | 2013-01-15 | Vivant Medical, Inc. | Articulating ablation device and method |
US20090198243A1 (en) | 2008-02-06 | 2009-08-06 | Melsheimer Jeffry S | Device and method for stabilizing a damaged bone with a bone cement mixture |
US8262672B2 (en) | 2008-04-16 | 2012-09-11 | Medtronic, Inc. | Medical delivery device construction |
US7762164B2 (en) | 2008-06-02 | 2010-07-27 | Eca Medical Instruments | Torque-limiting device |
WO2009155319A1 (en) | 2008-06-17 | 2009-12-23 | Soteira, Inc. | Devices and methods for fracture reduction |
AU2009270307B2 (en) | 2008-07-15 | 2013-03-21 | Lorne Beckman | Bone cement injection device |
US20100076476A1 (en) | 2008-07-25 | 2010-03-25 | To John T | Systems and methods for cable-based tissue removal |
US8246627B2 (en) | 2008-08-07 | 2012-08-21 | Stryker Corporation | Cement delivery device for introducing cement into tissue, the device having a cavity creator |
US9101734B2 (en) | 2008-09-09 | 2015-08-11 | Biosense Webster, Inc. | Force-sensing catheter with bonded center strut |
US8758349B2 (en) * | 2008-10-13 | 2014-06-24 | Dfine, Inc. | Systems for treating a vertebral body |
EP2364128A4 (en) | 2008-09-30 | 2013-07-24 | Dfine Inc | SYSTEM FOR USE IN THE TREATMENT OF SPINE FRACTURES |
US20100114184A1 (en) | 2008-10-07 | 2010-05-06 | Brainsgate Ltd. | Flexible tools for preparing bony canals |
US8355799B2 (en) | 2008-12-12 | 2013-01-15 | Arthrocare Corporation | Systems and methods for limiting joint temperature |
JP2012515024A (ja) | 2009-01-15 | 2012-07-05 | キャスリックス リミテッド | 操向可能なスタイレット |
EP2424608B1 (en) | 2009-04-28 | 2014-03-19 | Avinger, Inc. | Guidewire support catheter |
WO2010135602A1 (en) | 2009-05-20 | 2010-11-25 | Osseon Therapeutics, Inc. | Steerable curvable ablation catheter for vertebroplasty |
US20100298832A1 (en) | 2009-05-20 | 2010-11-25 | Osseon Therapeutics, Inc. | Steerable curvable vertebroplasty drill |
US8057403B2 (en) | 2009-05-29 | 2011-11-15 | Promex Technologies, Inc. | Flexible biopsy needle |
US9616246B2 (en) | 2010-01-04 | 2017-04-11 | Covidien Lp | Apparatus and methods for treating hollow anatomical structures |
KR101150283B1 (ko) * | 2010-03-15 | 2012-05-24 | (주)엘앤케이바이오메드 | 본시멘트 주입기구 |
US8465488B2 (en) | 2010-03-16 | 2013-06-18 | Olympus Medical Systems Corporation | Endoscopic surgical instrument |
US10058336B2 (en) | 2010-04-08 | 2018-08-28 | Dfine, Inc. | System for use in treatment of vertebral fractures |
US9526507B2 (en) | 2010-04-29 | 2016-12-27 | Dfine, Inc. | System for use in treatment of vertebral fractures |
CN102958456B (zh) | 2010-04-29 | 2015-12-16 | Dfine有限公司 | 用于治疗椎骨骨折的系统 |
US9241762B2 (en) | 2010-06-03 | 2016-01-26 | Covidien Lp | Specific absorption rate measurement and energy-delivery device characterization using image analysis |
US9649116B2 (en) | 2010-11-22 | 2017-05-16 | Dfine, Inc. | System for use in treatment of vertebral fractures |
US8560086B2 (en) | 2010-12-02 | 2013-10-15 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter electrode assemblies and methods of construction therefor |
US9427281B2 (en) | 2011-03-11 | 2016-08-30 | Medtronic Advanced Energy Llc | Bronchoscope-compatible catheter provided with electrosurgical device |
US20120277582A1 (en) * | 2011-04-26 | 2012-11-01 | Kyphon Sarl | Devices and methods for osteolytic lesion assessment using a steerable catheter |
JP6527329B2 (ja) | 2011-05-03 | 2019-06-05 | シファメド・ホールディングス・エルエルシー | 操縦可能な送達シース |
US9119639B2 (en) | 2011-08-09 | 2015-09-01 | DePuy Synthes Products, Inc. | Articulated cavity creator |
US20130072941A1 (en) * | 2011-09-16 | 2013-03-21 | Francisca Tan-Malecki | Cement Injector and Cement Injector Connectors, and Bone Cement Injector Assembly |
US20130237795A1 (en) | 2012-03-09 | 2013-09-12 | Carefusion 2200, Inc. | Performance concentric electromyography needle |
JP6130905B2 (ja) | 2012-03-27 | 2017-05-17 | ディファイン, インコーポレイテッド | 温度監視による組織焼灼体積の制御における使用のための方法およびシステム |
KR101342906B1 (ko) | 2012-10-25 | 2013-12-19 | 신경민 | 복수의 전극을 이용하는 어블레이션 시스템 및 이의 제어 방법 |
JP6195625B2 (ja) | 2012-11-05 | 2017-09-13 | リリーバント メドシステムズ、インコーポレイテッド | 骨を通して湾曲経路を作り、骨内で神経を調節するシステム及び方法 |
US9918766B2 (en) | 2012-12-12 | 2018-03-20 | Dfine, Inc. | Devices, methods and systems for affixing an access device to a vertebral body for the insertion of bone cement |
US9717551B2 (en) | 2013-02-21 | 2017-08-01 | Carefusion 2200, Inc. | Intravertebral tissue ablation device and method |
US9211161B2 (en) | 2013-03-06 | 2015-12-15 | DePuy Synthes Products, Inc. | Apparatus and methods for associating medical probes with connection ports |
US20150099997A1 (en) | 2013-10-03 | 2015-04-09 | Oz Cabiri | Steering tool |
EP3057517B1 (en) | 2013-10-15 | 2020-04-08 | Stryker Corporation | Device for creating a void space in a living tissue, the device including a handle with a control knob that can be set regardless of the orientation of the handle |
US9956038B2 (en) | 2014-03-24 | 2018-05-01 | Coral Sand Beach Llc | RF or microwave ablation catheter with remote dicke switch |
US9901392B2 (en) | 2015-05-11 | 2018-02-27 | Dfine, Inc. | System for use in treatment of vertebral fractures |
EP3397334A4 (en) | 2015-10-06 | 2019-08-07 | Halcyon Medical, Inc. | GANGLION-AORTICORENALE DETECTION |
SG11201807618QA (en) | 2016-03-15 | 2018-10-30 | Epix Therapeutics Inc | Improved devices, systems and methods for irrigated ablation |
AU2017363356B2 (en) | 2016-11-28 | 2023-02-09 | Dfine, Inc. | Tumor ablation devices and related methods |
WO2018129180A1 (en) | 2017-01-06 | 2018-07-12 | Dfine, Inc. | Osteotome with a distal portion for simultaneous advancement and articulation |
US20190357971A1 (en) | 2018-05-22 | 2019-11-28 | Viora Ltd. | Device, system and method for safe radio frequency treatment |
US10980599B2 (en) | 2018-07-05 | 2021-04-20 | Avent, Inc. | System and method for adjusting available power per probe during an ablation procedure |
EP3876856A4 (en) | 2018-11-08 | 2022-10-12 | Dfine, Inc. | TUMORABLATION DEVICE AND RELATED SYSTEMS AND METHODS |
-
2017
- 2017-10-25 WO PCT/US2017/058303 patent/WO2018081279A1/en unknown
- 2017-10-25 EP EP17863626.2A patent/EP3531934A4/en active Pending
- 2017-10-25 JP JP2019545883A patent/JP2019534130A/ja active Pending
- 2017-10-25 US US15/793,509 patent/US10478241B2/en active Active
- 2017-10-25 CN CN201780065478.4A patent/CN109862834B/zh active Active
-
2019
- 2019-11-11 US US16/680,056 patent/US11344350B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102985015A (zh) * | 2010-04-29 | 2013-03-20 | Dfine有限公司 | 用于治疗椎骨骨折的系统 |
CN102500036A (zh) * | 2011-11-17 | 2012-06-20 | 天津科技大学 | 一种磁导航式关节型穿刺针 |
CN103690228A (zh) * | 2013-12-12 | 2014-04-02 | 宁波华科润生物科技有限公司 | 椎体扩张球囊系统 |
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EP3531934A1 (en) | 2019-09-04 |
JP2019534130A (ja) | 2019-11-28 |
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