CN109843279A - 包含ssao/vap-1抑制剂和sglt2抑制剂的药物组合、其用途 - Google Patents
包含ssao/vap-1抑制剂和sglt2抑制剂的药物组合、其用途 Download PDFInfo
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- CN109843279A CN109843279A CN201780063937.5A CN201780063937A CN109843279A CN 109843279 A CN109843279 A CN 109843279A CN 201780063937 A CN201780063937 A CN 201780063937A CN 109843279 A CN109843279 A CN 109843279A
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- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP16194572.0 | 2016-10-19 | ||
| EP16194572 | 2016-10-19 | ||
| PCT/EP2017/076300 WO2018073154A1 (en) | 2016-10-19 | 2017-10-16 | Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof |
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| EP (1) | EP3528800A1 (https=) |
| JP (1) | JP2019531320A (https=) |
| KR (1) | KR20190070956A (https=) |
| CN (1) | CN109843279A (https=) |
| AU (1) | AU2017344882A1 (https=) |
| BR (1) | BR112019005930A2 (https=) |
| CA (1) | CA3041169A1 (https=) |
| CL (1) | CL2019000935A1 (https=) |
| EA (1) | EA201990951A1 (https=) |
| IL (1) | IL265989A (https=) |
| MX (1) | MX2019004549A (https=) |
| PH (1) | PH12019500845A1 (https=) |
| WO (1) | WO2018073154A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113893256A (zh) * | 2020-07-06 | 2022-01-07 | 诺未科技（北京）有限公司 | 化合物或其可药用盐、二聚体或三聚体在制备治疗癌症的药物中的应用 |
| CN115666577A (zh) * | 2020-03-25 | 2023-01-31 | 拓臻股份有限公司 | 呼吸道病症的治疗 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20190110736A (ko) | 2018-03-21 | 2019-10-01 | 주식회사유한양행 | 신규의 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| KR20190110740A (ko) | 2018-03-21 | 2019-10-01 | 주식회사유한양행 | 신규의 아릴 또는 헤테로아릴 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| MX2021003731A (es) * | 2018-09-28 | 2021-08-05 | Acucela Inc | Inhibidores de vap-1. |
| CN113164454A (zh) | 2018-09-28 | 2021-07-23 | 奥克塞拉有限公司 | Vap-1的抑制剂 |
| JP7414230B2 (ja) * | 2018-11-09 | 2024-01-16 | 国立大学法人 琉球大学 | 抗血液悪性腫瘍薬 |
| CN111320609A (zh) | 2018-12-13 | 2020-06-23 | 拓臻股份有限公司 | 一种THRβ受体激动剂化合物及其制备方法和用途 |
| TW202039486A (zh) * | 2018-12-14 | 2020-11-01 | 南韓商柳韓洋行股份有限公司 | 三唑并吡啶-3-酮化物或其鹽及包含彼之醫藥組合物 |
| TWI835945B (zh) * | 2018-12-14 | 2024-03-21 | 南韓商柳韓洋行股份有限公司 | 3,3-二氟烯丙胺化物或其鹽及包含彼的醫藥組合物 |
| AU2020336272A1 (en) | 2019-08-23 | 2022-04-14 | Terns Pharmaceuticals, Inc. | Thyroid hormone receptor beta agonist compounds |
| CN114375193B (zh) | 2019-09-12 | 2024-05-14 | 拓臻制药公司 | 甲状腺激素受体β激动剂化合物 |
| MX2022005199A (es) | 2019-10-29 | 2022-08-04 | Eccogene Shanghai Co Ltd | Inhibidores de ssao y uso de los mismos. |
| US20210379040A1 (en) * | 2020-05-13 | 2021-12-09 | Terns Pharmaceuticals, Inc. | Combination treatment of liver disorders |
| JP2023539639A (ja) | 2020-08-25 | 2023-09-15 | イーライ リリー アンド カンパニー | Ｓｓａｏ阻害剤の多形 |
| WO2022183289A1 (en) * | 2021-03-04 | 2022-09-09 | The Governors Of The University Of Alberta | The use of empagliflozin for the treatment of ulcerative colitis and crohn's disease |
| TW202327589A (zh) * | 2021-11-11 | 2023-07-16 | 美商拓臻製藥公司 | 肝病之組合療法 |
| CA3238102A1 (en) * | 2021-11-11 | 2023-05-19 | Terns Pharmaceuticals, Inc. | Treating liver disorders with an ssao inhibitor |
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| CN104520268A (zh) * | 2012-05-02 | 2015-04-15 | 法马克西斯制药公司 | Ssao的取代的3-卤代烯丙基胺抑制剂及其用途 |
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| ATE264337T1 (de) | 1999-08-31 | 2004-04-15 | Kissei Pharmaceutical | Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung |
| PH12000002657B1 (en) | 1999-10-12 | 2006-02-21 | Bristol Myers Squibb Co | C-aryl glucoside SGLT2 inhibitors |
| US6515117B2 (en) | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
| AU2002223127A1 (en) | 2000-11-30 | 2002-06-11 | Kissei Pharmaceutical Co., Ltd. Intellectual Property | Glucopyranosyloxybenzyl benzene derivatives, medicinal compositions containing the same and intermediates in the production thereof |
| PL209375B1 (pl) | 2000-12-28 | 2011-08-31 | Kissei Pharmaceutical | Pochodne glukopiranozyloksypirazolu, kompozycja farmaceutyczna zawierająca takie pochodne i zastosowanie tych pochodnych do wytwarzania kompozycji farmaceutycznej |
| JP4490109B2 (ja) | 2002-03-22 | 2010-06-23 | キッセイ薬品工業株式会社 | グルコピラノシルオキシベンジルベンゼン誘導体の結晶 |
| DE10231370B4 (de) | 2002-07-11 | 2006-04-06 | Sanofi-Aventis Deutschland Gmbh | Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel |
| ES2567571T3 (es) | 2003-03-14 | 2016-04-25 | Astellas Pharma Inc. | Derivados de C-glucósido y sales de los mismos |
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2017
- 2017-10-16 BR BR112019005930A patent/BR112019005930A2/pt not_active IP Right Cessation
- 2017-10-16 EP EP17804068.9A patent/EP3528800A1/en not_active Withdrawn
- 2017-10-16 CA CA3041169A patent/CA3041169A1/en not_active Abandoned
- 2017-10-16 AU AU2017344882A patent/AU2017344882A1/en not_active Abandoned
- 2017-10-16 KR KR1020197014347A patent/KR20190070956A/ko not_active Withdrawn
- 2017-10-16 WO PCT/EP2017/076300 patent/WO2018073154A1/en not_active Ceased
- 2017-10-16 CN CN201780063937.5A patent/CN109843279A/zh active Pending
- 2017-10-16 US US16/341,460 patent/US20210212968A1/en not_active Abandoned
- 2017-10-16 MX MX2019004549A patent/MX2019004549A/es unknown
- 2017-10-16 JP JP2019520691A patent/JP2019531320A/ja active Pending
- 2017-10-16 EA EA201990951A patent/EA201990951A1/ru unknown
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2019
- 2019-04-08 CL CL2019000935A patent/CL2019000935A1/es unknown
- 2019-04-11 IL IL265989A patent/IL265989A/en unknown
- 2019-04-17 PH PH12019500845A patent/PH12019500845A1/en unknown
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115666577A (zh) * | 2020-03-25 | 2023-01-31 | 拓臻股份有限公司 | 呼吸道病症的治疗 |
| CN113893256A (zh) * | 2020-07-06 | 2022-01-07 | 诺未科技（北京）有限公司 | 化合物或其可药用盐、二聚体或三聚体在制备治疗癌症的药物中的应用 |
| WO2022007134A1 (zh) * | 2020-07-06 | 2022-01-13 | 诺未科技（北京）有限公司 | 化合物或其可药用盐、二聚体或三聚体在制备治疗癌症的药物中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20190070956A (ko) | 2019-06-21 |
| MX2019004549A (es) | 2019-06-12 |
| BR112019005930A2 (pt) | 2019-06-11 |
| JP2019531320A (ja) | 2019-10-31 |
| CA3041169A1 (en) | 2018-04-26 |
| EP3528800A1 (en) | 2019-08-28 |
| EA201990951A1 (ru) | 2019-11-29 |
| PH12019500845A1 (en) | 2019-12-02 |
| WO2018073154A1 (en) | 2018-04-26 |
| IL265989A (en) | 2019-06-30 |
| CL2019000935A1 (es) | 2019-08-09 |
| US20210212968A1 (en) | 2021-07-15 |
| AU2017344882A1 (en) | 2019-03-28 |
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