CN109771308A - A kind of formula and preparation method of striae of pregnancy reparation - Google Patents
A kind of formula and preparation method of striae of pregnancy reparation Download PDFInfo
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- CN109771308A CN109771308A CN201810530666.6A CN201810530666A CN109771308A CN 109771308 A CN109771308 A CN 109771308A CN 201810530666 A CN201810530666 A CN 201810530666A CN 109771308 A CN109771308 A CN 109771308A
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Abstract
The invention discloses the formulas and preparation method of a kind of striae of pregnancy reparation, and formula includes: A phase, B phase, C phase, D phase, E phase, F phase, using specific proportion, it is major ingredient by regeneration silicon materials, asiaticosid, growth factor, bioabsorbable polymer material etc. is auxiliary material compounds other auxiliary agents and is made；Wherein: regeneration silicon materials are conducive to the ordering growth of cell from the reparation of source property as capable of being formed of having of main component and the consistent three-dimensional netted supporting structure of skeleton and soft tissue structure, realization cell, and promotion collagen gene is expressed；Asiaticosid and regeneration silicon are synergistic, and growth factor provides collagen carrier for skin, and bioabsorbable polymer material increases the adhesiveness of regeneration silicon materials and skin histology, restore skin elasticity；Other auxiliary agents promote absorption of the striae of pregnancy position to preparation；The ingredient collective effect makes to form reasonable regulatory mechanism in striae of pregnancy repair process, promotes collagen and elastin ordering growth, desalinates striae of pregnancy lines, keeps loose skin full and flexible.
Description
Technical field
The present invention relates to the formulas and preparation method of a kind of striae of pregnancy reparation.
Background technique
The formation of striae of pregnancy is mainly due to the gestational period hormonal influence, and abdominal distention makes the elastic fibers of skin in addition
It damages or is broken with collagenous fibres, skin of abdomen is thinning to attenuate, and it is different, different in size pink or purplish red some width occur
The wavy decorative pattern of color.After childbirth, these decorative patterns can fade away, and leave white or argenteous glossiness scar strain line,
That is striae of pregnancy.Striae of pregnancy mainly appears on stomach wall, it is also possible to appear in outside, buttocks, chest, rear waist and arm in thigh
Etc..Primipara is the most obvious.And with cutis laxa, breast tenesmus, abdominal fat accumulation, women's postpartum has been seriously affected
Posture and physical and mental health.Inherently to solve the problems, such as striae of pregnancy, a kind of preparation can restore Elastic fibers and collagen
Fibre property promotes the orderly generation of skin elasticity albumen and collagen, keeps loose skin full and flexible, while energy
Enough desalinate microgroove.
Summary of the invention
In view of this, restoring the main purpose of the present invention is to provide the formula and preparation method of a kind of striae of pregnancy reparation
Elastic fibers and collagenous fibres performance promote the orderly generation of skin elasticity albumen and collagen, make loose skin
It is full and flexible, desalinate microgroove.
In order to achieve the above objectives, the technical scheme of the present invention is realized as follows: a kind of formula of striae of pregnancy reparation, special
Sign is, including following parts by weight formula:
A phase: -25 1-3 parts of ceteareth of 4-8 parts of ethylhexyl palmitate
2-5 parts of caprylic/capric triglyceride of 1.8-2.4 parts of cetanol
- 6 1-3 parts of ceteareth of 0.8-1.2 parts of tocopherol acetate
1-4 parts of Butyrospermum parkii fruit fatty oil
B phase: 0.2-0.4 parts of xanthan gum of 6-10 parts of glycerol
0.06-0.1 parts of Sodium Hyaluronate of 0.1 part of carboxymethyl chitosan
1-3 parts of poly (sodium aspartate)
C phase: 50-60 parts of deionized water
0.1-0.5 parts of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: silicon materials 3-15 parts 5-15 parts of polyethylene glycol 400 of regeneration
E phase: 0.1-0.5 parts of acetyl hydroxyproline of 2-3 parts of citric acid
0.1-0.3 parts of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.02-0.5
Benzyl alcohol 0.02-0.5
1,2 hexylene glycol 0.2-0.8
As another object of the present invention, also resides in and a kind of preparation method of the formula of striae of pregnancy reparation is provided, which is characterized in that
Include:
Firstly, A is added in oily phase tank, it is warming up to 60-90 DEG C, it is spare；
Then, B, C, D and E are added in water phase tank, are warming up to 75-85 DEG C, it is spare；
Solution is added in oily phase tank in water phase tank, and homogeneous 10 minutes
Temperature is down to 45 DEG C of addition F phases and is stirred evenly, cooling；
36 DEG C of discharging detections；
The present invention have compared with the existing technology it is below the utility model has the advantages that
Realize that simply formula includes: A phase, B phase, C phase, D phase, E phase, F phase, using specific proportion, based on regeneration silicon materials
Material, Sodium Hyaluronate, asiaticosid, growth factor etc. are auxiliary material compounds other auxiliary agents and is made；Silicon materials are regenerated as main
What ingredient had can form and the consistent three-dimensional netted supporting structure of skeleton and soft tissue structure, realize that cell is repaired from source property
It is multiple, be conducive to the ordering growth of cell, promote collagen gene expression；Asiaticosid and regeneration silicon are synergistic, growth because
Son provides collagen carrier, and bioabsorbable polymer material increases the adhesiveness of regeneration silicon materials and skin histology, restores skin
Elasticity；Other auxiliary agents promote absorption of the striae of pregnancy position to preparation；Other auxiliary agents promote absorption of the striae of pregnancy to preparation, it is described at
Point collective effect makes to form reasonable regulatory mechanism in striae of pregnancy repair process, and collagen and elastin is promoted orderly to give birth to
It is long, keep loose skin full and flexible.
Specific embodiment
For the ease of being further understood to invention, a specific embodiment of the invention is done further specifically below
It is bright.
Embodiment 1
A kind of formula of striae of pregnancy reparation, which is characterized in that including following parts by weight formula:
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 58.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: regeneration 5 parts of silicon materials, 5 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3
The present embodiment provides a kind of preparation methods of the formula of striae of pregnancy reparation, comprising:
Firstly, A is added in oily phase tank, it is warming up to 60-90 DEG C, it is spare；
Then, B, C, D and E are added in water phase tank, are warming up to 75-85 DEG C, it is spare；
Solution is added in oily phase tank in water phase tank, and homogeneous 10 minutes
Temperature is down to 45 DEG C of addition F phases and is stirred evenly, cooling；
36 DEG C of discharging detections；
Wherein,
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 58.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: regeneration 5 parts of silicon materials, 5 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3
Preferably, every part of silicon materials of the regeneration includes: the activity with tridimensional network that mass percent is 40-70%
Silica, in conjunction with being uniformly distributed calcium, phosphorus, the na oxide that mass percent therein is 30-60%, and active silica
In the mixture containing the high coordination silicon atom in part.Regulate and control the degradation speed of product in vivo by adjusting the content of phosphorus, solves
It has determined the complete creeping substitution of cambium, has realized cambium from form, structure, full-featured reparative regeneration.
Preferably, the partial size of 60% or more powder is less than 20um in the active silica, which regenerates silicon
Powder specific-surface area detection is big, and reaction speed is fast, can obtain quick therapeutic effect.
Preferably, the Sodium Hyaluronate molecular weight is in 100-200 ten thousand.The molecular weight of poly (sodium aspartate) within 10,000,
Can softening skin, increase skin elasticity.
Preferably, growth factor and acetyl hydroxyproline provide collagen and generate carrier.
Preferably, -25 stable emulsions of ceteareth -6, the ceteareth of the specific proportion are made
With.
Preferably, the ethylhexyl palmitate of the specific proportion, caprylic/capric triglyceride, tocopherol acetate, ox
Oily fruit tree (BUTYROSPERMUM PARKII) fruit fatty oil promotes absorption of the skin to regeneration silicon materials.
Embodiment 2
A kind of formula of striae of pregnancy reparation, which is characterized in that including following parts by weight formula:
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 52.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: regeneration 8 parts of silicon materials, 8 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3
The present embodiment provides a kind of preparation methods of the formula of striae of pregnancy reparation, comprising:
Firstly, A is added in oily phase tank, it is warming up to 60-90 DEG C, it is spare；
Then, B, C, D and E are added in water phase tank, are warming up to 75-85 DEG C, it is spare；
Solution is added in oily phase tank in water phase tank, and homogeneous 10 minutes
Temperature is down to 45 DEG C of addition F phases and is stirred evenly, cooling；
36 DEG C of discharging detections；
Wherein,
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 52.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: regeneration 8 parts of silicon materials, 8 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3
Preferably, every part of silicon materials of the regeneration includes: the activity with tridimensional network that mass percent is 40-70%
Silica, in conjunction with being uniformly distributed calcium, phosphorus, the na oxide that mass percent therein is 30-60%, and active silica
In the mixture containing the high coordination silicon atom in part.Regulate and control the degradation speed of product in vivo by adjusting the content of phosphorus, solves
It has determined the complete creeping substitution of cambium, has realized cambium from form, structure, full-featured reparative regeneration.
Preferably, the partial size of 60% or more powder is less than 20um in the active silica, which regenerates silicon
Powder specific-surface area detection is big, and reaction speed is fast, can obtain quick therapeutic effect.
Preferably, the Sodium Hyaluronate number-average molecular weight is between 100-200 ten thousand.The molecular weight of poly (sodium aspartate) exists
Within 10000
Preferably, growth factor and acetyl hydroxyproline provide collagen and generate carrier.
Preferably, -25 stable emulsions of ceteareth -6, the ceteareth of the specific proportion are made
With.
Preferably, the ethylhexyl palmitate of the specific proportion, caprylic/capric triglyceride, tocopherol acetate, ox
Oily fruit tree (BUTYROSPERMUM PARKII) fruit fatty oil promotes absorption of the skin to regeneration silicon materials.
Embodiment 3
A kind of formula of striae of pregnancy reparation, which is characterized in that including following parts by weight formula:
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 48.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: regeneration 10 parts of silicon materials, 10 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3
The present embodiment provides a kind of preparation methods of the formula of striae of pregnancy reparation, comprising:
Firstly, A is added in oily phase tank, it is warming up to 60-90 DEG C, it is spare；
Then, B, C, D and E are added in water phase tank, are warming up to 75-85 DEG C, it is spare；
Solution is added in oily phase tank in water phase tank, and homogeneous 10 minutes
Temperature is down to 45 DEG C of addition F phases and is stirred evenly, cooling；
36 DEG C of discharging detections；
Wherein,
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 48.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: regeneration 10 parts of silicon materials, 10 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3
Preferably, every part of silicon materials of the regeneration includes: the activity with tridimensional network that mass percent is 40-70%
Silica, in conjunction with being uniformly distributed calcium, phosphorus, the na oxide that mass percent therein is 30-60%, and active silica
In the mixture containing the high coordination silicon atom in part.Regulate and control the degradation speed of product in vivo by adjusting the content of phosphorus, solves
It has determined the complete creeping substitution of cambium, has realized cambium from form, structure, full-featured reparative regeneration.
Preferably, the partial size of 60% or more powder is less than 20um in the active silica, which regenerates silicon
Powder specific-surface area detection is big, and reaction speed is fast, can obtain quick therapeutic effect.
Preferably, the Sodium Hyaluronate number-average molecular weight is between 100-200 ten thousand.The molecular weight of poly (sodium aspartate) exists
Within 10000, can softening skin, increase skin elasticity.
Preferably, growth factor and acetyl hydroxyproline provide collagen and generate carrier.
Preferably, -25 stable emulsions of ceteareth -6, the ceteareth of the specific proportion are made
With.
Preferably, the ethylhexyl palmitate of the specific proportion, caprylic/capric triglyceride, tocopherol acetate, ox
Oily fruit tree (BUTYROSPERMUM PARKII) fruit fatty oil promotes absorption of the skin to regeneration silicon materials.
Test:
Effectiveness indicator of the invention compares, and to verify whether striae of pregnancy reparation of the present invention reaches expected invention effect, passes through doctor
The modes such as Out-patient Department and network collection are selected with striae of pregnancy people 120, basic condition are as follows: above-mentioned case is randomly divided into four
Group, but guarantee every group of case for having different origins；Then it is used as experimental group for three groups, one group as a control group；Change regeneration silicon
Material additive amount adds 6 parts, 8 parts, 10 parts of three groups of samples respectively, is denoted as No. 1, No. 2, No. 3 samples respectively from less to more by additive amount
Product, i.e. embodiment 1-3.Three groups of experimental groups respectively with 1 prepared by embodiment of the present invention first part, 2, No. 3 samples it is direct
Act on skin area；Control group use compound centella gelatification in striae of pregnancy as control；1# test group 30,2# test
Group 30,3# test group 30, control group 30.The application method of experimental group preparation are as follows: appropriate this product is taken to be applied to after clean skin
Striae of pregnancy position gently claps bullet to absorbing, then gently massages 5min or so, 2-3 times daily；15 days as a treatment course, observation
Curative effect.
Curative effect determinate standard (1) recovery from illness: striae of pregnancy lines obviously desalinates or disappears, and relaxation skin restores elasticity, and (2) are good
Turn: striae of pregnancy lines has faint desalination (3) without effect: diseased region is without significant change before and after medication.
Treatment results, such as following table
It is as shown in the table for curative effect: experimental group cure rate is all 90% or more, and control group cure rate is 48.39%, it is clear that
Difference on effect is larger；And it is optimal to compare visible No. 2 experimental groups with regard to three groups of experimental groups, and No. 1, No. 2, No. 3 experimental group differences are
Regeneration silicon materials content is followed successively by 6%, 8%, 12%, therefore regenerating silicon materials most preferred content is 8%, and as content increase is controlled
More effect is not increasing.
The present invention establishes Reasonable Regulation And Control mechanism, the Absorption Growth factor in striae of pregnancy treatment using the regeneration silicon materials,
Collagen makes its ordering growth, inherently solves the problems, such as striae of pregnancy.
Cure mechanism of the invention, which belongs to from cell level, promotes healthy cell expression, inhibits and metabolism sick cell reaches
Treating both manifestation and root cause of disease, therefore without rebound phenomenon after treatment end.
Preparation of the present invention promotes striae of pregnancy position and skin to having in striae of pregnancy therapeutic process, through compound auxiliary
Effect ingredient is fully absorbed and is played a role, and does not have to carry out second operation wound；And preparation is mild, will not be irritating to the skin work
With.
The invention discloses the formulas and preparation method of a kind of striae of pregnancy reparation, and formula includes: A phase, B phase, C phase, D
Phase, E phase, F phase are major ingredient, asiaticosid, growth factor, bioabsorbable polymer material etc. by regeneration silicon materials using specific proportion
For auxiliary material compounds other auxiliary agents and is made；Wherein: regeneration silicon materials as capable of being formed of having of main component and skeleton and
The consistent three-dimensional netted supporting structure of soft tissue structure is realized that cell from the reparation of source property, is conducive to the ordering growth of cell, is promoted
Collagen gene expression；Asiaticosid and regeneration silicon are synergistic, and growth factor provides collagen carrier for skin, biology
High molecular material increases the adhesiveness of regeneration silicon materials and skin histology, restores skin elasticity；Other auxiliary agents promote striae of pregnancy
Absorption of the position to preparation；The ingredient collective effect makes to form reasonable regulatory mechanism in striae of pregnancy repair process, promotes glue
Former albumen and elastin ordering growth desalinate striae of pregnancy lines, keep loose skin full and flexible.
Claims (8)
1. a kind of formula of striae of pregnancy reparation, which is characterized in that including following parts by weight formula:
A phase: -25 1-3 parts of ceteareth of 4-8 parts of ethylhexyl palmitate
2-5 parts of caprylic/capric triglyceride of 1.8-2.4 parts of cetanol
- 6 1-3 parts of ceteareth of 0.8-1.2 parts of tocopherol acetate
1-4 parts of Butyrospermum parkii fruit fatty oil
B phase: 0.2-0.4 parts of xanthan gum of 6-10 parts of glycerol
0.06-0.1 parts of Sodium Hyaluronate of 0.1 part of carboxymethyl chitosan
1-3 parts of poly (sodium aspartate)
C phase: 50-60 parts of deionized water
0.1-0.5 parts of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.2-2 parts of growth factor
D phase: silicon materials 3-15 parts 5-15 parts of polyethylene glycol 400 of regeneration
E phase: 0.1-0.5 parts of acetyl hydroxyproline of 2-3 parts of citric acid
0.1-0.3 parts of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.02-0.5
Benzyl alcohol 0.02-0.5
1,2 hexylene glycol 0.2-0.8.
2. the formula of striae of pregnancy reparation according to claim 1, which is characterized in that including following parts by weight formula:
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 58.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.2 part of asiaticosid
0.1 part of growth factor
D phase: regeneration 5 parts of silicon materials, 5 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3.
3. the formula of scar reparation according to claim 1, which is characterized in that including following parts by weight formula:
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 52.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.2 part of asiaticosid
0.1 part of growth factor
D phase: regeneration 8 parts of silicon materials, 8 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3.
4. the formula of scar reparation according to claim 1, which is characterized in that including following parts by weight formula:
A phase: 6 parts of ethylhexyl palmitate, 2 parts of ceteareth -25
2 parts of cetanol, 2 parts of caprylic/capric triglyceride
1 part of tocopherol acetate, 1 part of ceteareth -6
3 parts of Butyrospermum parkii fruit fatty oil
B phase: 8 parts of glycerol, 0.3 part of xanthan gum
0.1 part of carboxymethyl chitosan, 0.1 part of Sodium Hyaluronate
2 parts of poly (sodium aspartate)
C phase: 48.9 parts of deionized water
0.2 part of aloe barbadensis Miller leaf extract
0.2 part of asiaticosid
0.1 part of growth factor
D phase: regeneration 10 parts of silicon materials, 10 parts of polyethylene glycol 400
E phase: 2.5 parts of citric acid, 0.1 part of acetyl hydroxyproline
0.1 part of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.05
Benzyl alcohol 0.05
1,2 hexylene glycols 0.3.
5. the formula of scar reparation according to claim 1, it is characterised in that: every part of silicon materials of the regeneration includes: matter
The active silica with tridimensional network that percentage is 40-70% is measured, in conjunction with being uniformly distributed mass percent therein
Mixture for the calcium, phosphorus, na oxide of 30-60%, and containing the high coordination silicon atom in part in active silica.
6. the formula of scar reparation according to claim 6, it is characterised in that: the molecular weight of the Sodium Hyaluronate exists
Between 100-200 ten thousand, the molecular weight of poly (sodium aspartate) is between 1-2 ten thousand.
7. the formula of scar reparation according to claim 6, it is characterised in that: 60% or more in the active silica
The partial size of powder is less than 20um.
8. a kind of preparation method of the formula of striae of pregnancy reparation characterized by comprising
Firstly, A is added in oily phase tank, it is warming up to 60-90 DEG C, it is spare；
Then, B, C, D and E are added in water phase tank, are warming up to 75-85 DEG C, it is spare；
Solution is added in oily phase tank in water phase tank, and homogeneous 10 minutes；
Temperature is down to 45 DEG C of addition F phases and is stirred evenly, cooling；
36 DEG C of discharging detections；
Wherein,
A phase: -25 1-3 parts of ceteareth of 4-8 parts of ethylhexyl palmitate
2-5 parts of caprylic/capric triglyceride of 1.8-2.4 parts of cetanol
- 6 1-3 parts of ceteareth of 0.8-1.2 parts of tocopherol acetate
1-4 parts of Butyrospermum parkii fruit fatty oil
B phase: 0.2-0.4 parts of xanthan gum of 6-10 parts of glycerol
0.06-0.1 parts of Sodium Hyaluronate of 0.1 part of carboxymethyl chitosan
1-3 parts of poly (sodium aspartate)
C phase: 50-60 parts of deionized water
0.1-0.5 parts of aloe barbadensis Miller leaf extract
0.1-0.5 parts of asiaticosid
0.05-0.2 parts of growth factor
D phase: silicon materials 3-15 parts 5-15 parts of polyethylene glycol 400 of regeneration
E phase: 0.1-0.5 parts of acetyl hydroxyproline of 2-3 parts of citric acid
0.1-0.3 parts of 2-o- ethylascorbyl
F phase: dehydroactic acid 0.02-0.5
Benzyl alcohol 0.02-0.5
1,2 hexylene glycol 0.2-0.8.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN112006938A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Damaged skin repairing gel and preparation process thereof |
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