CN109718184A - A kind of combined extracts of plant whitening agent - Google Patents

A kind of combined extracts of plant whitening agent Download PDF

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Publication number
CN109718184A
CN109718184A CN201910182930.6A CN201910182930A CN109718184A CN 109718184 A CN109718184 A CN 109718184A CN 201910182930 A CN201910182930 A CN 201910182930A CN 109718184 A CN109718184 A CN 109718184A
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CN
China
Prior art keywords
extraction
combined extracts
whitening agent
plant whitening
skin
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Pending
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CN201910182930.6A
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Chinese (zh)
Inventor
侯占军
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Beiwencao Biotechnology (shanghai) Co Ltd
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Beiwencao Biotechnology (shanghai) Co Ltd
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Priority to CN201910182930.6A priority Critical patent/CN109718184A/en
Publication of CN109718184A publication Critical patent/CN109718184A/en
Pending legal-status Critical Current

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  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of combined extracts of plant whitening agent, it is the cosmetic additive agent being prepared by the raw material of following weight proportion: mulberry root skin 10%-20%, bletilla striata 10%-20%, Rhizoma Chuanxiong 5%-15%, wild marjoram 10%-20%, safflower 0.01%-0.05%, fruit of glossy privet 10%-20%, turmeric 5%-15%, Rehmannia glutinosa 10%-20%, Radix Glycyrrhizae 5%-15%.Extraction solvent of the invention: the 1.3- propylene glycol that Extraction solvent is 70%.The present invention is applied to prepare in releive antianaphylactic skin care item, including facial mask, water, essence, milky lotion, cream and cleaning product, additive amount 1-3%.

Description

A kind of combined extracts of plant whitening agent
Technical field
The present invention relates to a kind of combined extracts of plant whitening agent, the combination of specially a kind of plant whitening agent is extracted Object.
Background technique
With the development and improvement of living standard of society, more and more women extremely pay close attention to the pale of skin.But It is to be influenced by factors such as ultraviolet light irradiation, environmental pollution, endocrine disorder, heredity, causes Melanin Metabolism abnormal, melanocyte The melanocyte of secretion increases and makes local skin blackening, pigmentation et al. body colour after generation freckle, chloasma, senile plaque and inflammation The pigmented disease of element.Although traditional whitening active ingredients hydrogen peroxide, mercury and mercuric compounds and phenol derivatives, can reach The effect of quick whitening, but it is with adverse reactions such as cytotoxicity, irritation, sensitizations, it is banned at present for making up In product.Therefore, finding natural, the safe and efficient plant whitening active constituent of a new generation becomes the heat studied both at home and abroad in recent years One of point.
Chromatodermatosis such as freckle (heredity), chloasma (incretion), sunburn (inflammatory), riel blacking Sick (metabolic) etc. is beautiful because influencing, more and more patient's an urgent demand treatments, thus generates a large amount of whitening and freckle-removing product, Wherein, Chinese medicine whitening product is favourably welcome with its unique advantage (safety, irritation is small, Small side effects).
The color of human skin depends on the content and distribution of melanin, and the physiology course that melanin is formed substantially can be general It includes are as follows: melanocyte generates melanin, and melanin granule is shifted to epithelial cells by melanocyte dendritic processes, turned The melanin granule for moving to epithelial cells goes upward to cuticula with epidermal cell and falls off and drain with cuticula.But due to by Ultraviolet light, heredity, endocrine, the influence of inflammation and the factors such as improper diet, melanin metabolic disorder, the too fast increasing of dermal melanin It is long and be unevenly distributed and cause local skin excessively black and pigmentation, it is sick to show as pigmentation etc. after chloasma, freckle and inflammation Disease.During developing whitening agent, efficacy active component must have following one or more of functions: inhibit melanocyte Proliferation;Melanin is inhibited to be formed;Melanin granule is inhibited to be transferred to epithelial cells;Accelerate in epithelial cells melanin to cuticula Transfer;Cutin-softening layer and acceleration cuticula fall off;Extrinsic factor such as ultraviolet light, oxygen radical etc. is reduced to form melanin The negative effect of physiology course.
Summary of the invention
The present invention provides a kind of combined extracts of plant whitening agent, it be by the raw material preparation of following weight proportion and At cosmetic additive agent:
Mulberry root skin 10%-20%, bletilla striata 10%-20%, Rhizoma Chuanxiong 5%-15%, wild marjoram 10%-20%, safflower 0.01%- 0.05%, fruit of glossy privet 10%-20%, turmeric 5%-15%, Rehmannia glutinosa 10%-20%, Radix Glycyrrhizae 5%-15%.
Extraction solvent of the invention: the 1.3- propylene glycol that Extraction solvent is 70%.
Extracting method of the invention, ultrasonic cryogenic extraction.Particular content is as follows:
Pharmaceutical composition and 1.3- propylene glycol are mixed according to the ratio of 1:3, under conditions of temperature is 50-60 DEG C, low speed Stirring is impregnated 24 hours, and ultrasonic extraction in 30 minutes is then carried out.After extraction, coarse filtration separation, laggard andante formula mistake are carried out Filter finally carries out low temperature sedimentation, final composite extract is obtained after separation.
The present invention is applied to prepare releive antianaphylactic skin care item, including facial mask, water, essence, milky lotion, cream and washing In product, additive amount 1-3%.
Mulberry root bark extract contains reduced sugar, pentosan and galactolipin acid anhydride, tannin, flavonoids etc..It can inhibit elastin laminin Enzyme plays the role of anti-ageing;Promote the synthesis of fiber sprout cell brain amide, Palmitoleic Acid;To the Cuo because of the higher initiation of male sex hormone Sore can prevent and treat well;There is contraction to collagenous fibres, can be used for reducing weight;There is facilitation to the activation of luciferase, Illustrate that there is anti-inflammatory effect;The activity that can inhibit tyrosinase, has effects that whitening.
Bletilla striata extract has inhibiting effect to 5a- reductase, illustrates that extract takes off to because caused by male sex hormone is higher Hair has good preventive and therapeutic effect, can be used for hair tonic, acne product;Bletilla striata extract or the apparent antioxidant of effect, skin Whitening agent and anti-inflammatory agent.
Rhizoma Chuanxiong can inhibit the generation of free radical, effective scavenging activated oxygen;Under low concentration, melanin can be effectively suppressed The activity of cell reduces the generation of melanin, but excessive concentration then shows its cytotoxic effect;There is hygroscopicity simultaneously, have There is moisture-keeping function.
Be generally adopted by the extract of its herb in wild marjoram cosmetics, sweet wild marjoram leaf contains volatile component, as terpinene, Terpinol, linalool, methyl chavicol, Cineole, eugenol etc.;Involatile constituent has ursolic acid, carnosic acid Deng.Sweet wild marjoram leaf essential oil has antibiotic property, to hay bacillus, Escherichia coli, staphylococcus aureus and Streptococcus mutans, acarid etc. There is antibacterial action.It there are no the unsafe report of external application at present, furthermore marjoram oil can be used as the fragrance of food blending.Sweet wild marjoram It can be used as antibacterial agent, anti-mite agent, moisturizer, spectrum antioxidant, skin-whitening agents, anti-inflammatory agent etc. to extract.
Natural pigment carthamin yellow and safflower red pigment that safflower is extracted from safflower etc., safety edible are used, be can be used as The coloring agent of the cosmetics of super quality;Safflower extract have the effects that promoting blood circulation, it is anti-inflammatory, anti-oxidant, by improve skin blood circulation, Promote skin metabolism, remove free radical, inhibit melanin deposition, accelerate ecchymose removing decoloration, absorb ultraviolet light etc., play beauty White, sun-proof, anti-aging function, and have therapeutic effect to contact dermatitis, seborrheic dermatitis, pruritus, neurodermatitis; Safflower oil can be used as cosmetics oiliness raw material, the multiple nutritional components of profound level supplement skin.
The fruit of glossy privet derives from the fruit of the fruit of glossy privet, glucose, mannitol and oleanolic acid rich in etc. in extract Multiple efficacies ingredient, can effectively clear interior free yl, and delaying skin aging improves skin health state.
Turmeric has good inhibiting effect to pityrosporum furfur, facilitates dandruff reduction, is used for anti-dandruff;To luciferase Strong activation illustrates there is good anti-inflammatory power, can prevent and treat various dermatopathies;There is inhibition to brain amidase, thus Maintain the amount of cortex midbrain amide, can Palmitoleic Acid can be used in conjunction with it to the inhibition of elastoser and outstanding moisture holding capacity In conditioning skin.
Rehmannia glutinosa takes object to have facilitation to Filaggrin growth, shows play the role of enhancing skin metabolism, can change The composition for becoming sebum can be in inhibiting oiliness, skin softening and moisturizing cosmetics in conjunction with its wettability power under low-humidity environment With;Promotion of the glutinous rehmannia extract to cathepsin D-activity, display can control dermatitis;It can also be in weight-reducing, hair tonic and black hair product It uses.
Proliferation function of the licorice to myocyte, the facilitation to vascular endothelial cell proliferation, to collagen- The promotion that 4 types generate, the studies have shown thats licorice such as inhibition that NO is generated improve skin in terms of have promotion Effect, can be used for anti-ageing cosmetics;Licorice has inhibition melanin, the effect of skin whitening simultaneously;To some bacteriums It significantly inhibits, can be used as anti-inflammatory agent.
Specific embodiment
A kind of combined extracts of the plant whitening agent of embodiment 1;
By mulberry root skin, the bletilla striata, Rhizoma Chuanxiong, wild marjoram, safflower, the fruit of glossy privet, turmeric, Rehmannia glutinosa, Radix Glycyrrhizae.After washing, it is put into air blast It is sufficiently dry in drying box.
Weigh dry mulberry root skin 300g, bletilla striata 300g, Rhizoma Chuanxiong 200g, wild marjoram 300g, safflower 0.1g, fruit of glossy privet 300g, Turmeric 200g, Rehmannia glutinosa 300g, Radix Glycyrrhizae 200g.
It crushes.
The Chinese herbal medicine of crushing is put into constant temperature extracting tank.
70%1.3- propylene glycol 2.1KG is added, temperature maintains 55 DEG C, is slowly stirred, and impregnates 8 hours.
After immersion, progress ultrasonic extraction, interrupted extraction 30 minutes.
It is filtered with plate filter, is put into cryopreservation tank and is settled, settled 72 hours, take the supernatant to be Finished product.
A kind of application of the combined extracts of the plant whitening agent of embodiment 2 in facial mask
The constituent and content (%) of facial mask are as follows:
The combined extracts of plant whitening agent: 1
Water: 92.55
Glycerol: 3
EDTA:0.05
Sodium Hyaluronate: 0.05
Xanthan gum: 0.1
Carbomer: 0.15
Glycine betaine: 1.5
Arginine: 0.12
1.2- hexylene glycol: 0.5
Parahydroxyacet-ophenone: 0.5
Facial mask the preparation method is as follows:
By the combined extracts 1Kg of plant whitening agent, water 92.55Kg, glycerol 3Kg, EDTA 0.05Kg, Sodium Hyaluronate 0.05Kg, xanthan gum 0.1Kg, carbomer 0.15Kg, glycine betaine 1.5Kg are put into kettle, are heated to 85 DEG C, are stirred 30 minutes, It homogeneous 3 minutes, is uniformly dispersed.
40 DEG C of addition arginine 0.12Kg are cooled to, are stirred evenly.
It is down to room temperature and 1.2- hexylene glycol 0.5Kg, parahydroxyacet-ophenone 0.5Kg is added, stir evenly.
Film cloth is added, so that it may as people's natural whitening mask used in everyday in ready-made facial mask essence.
A kind of application of the combined extracts of the plant whitening agent of embodiment 3 in frost
The constituent and content (%) of frost are as follows:
The combined extracts of plant whitening agent: 2
Water: 81.9
Glycerol: 3
EDTA:0.05
Sodium Hyaluronate: 0.05
Acrylamide dimethyltaurine ammonium/VP copolymer: 1
Glycine betaine: 1.5
The smooth olive oleate of cetearyl glucoside, sorb, cetostearyl alcohol: 1.5
Caprylic/capric triglyceride: 8
1.2- hexylene glycol: 0.5
Parahydroxyacet-ophenone: 0.5
Frost the preparation method is as follows:
By the combined extracts 2Kg, water 80.9Kg, glycerol 3Kg, EDTA0.05Kg, Sodium Hyaluronate of plant whitening agent 0.05Kg, acrylamide dimethyltaurine ammonium/VP copolymer 1 Kg, glycine betaine 1.5Kg are put into emulsion pot, are heated to 85 DEG C, Stirring 30 minutes, homogeneous 3 minutes, is uniformly dispersed.
By cetearyl glucoside, the smooth olive oleate of sorb, cetostearyl alcohol 1.5Kg, caprylic/capric triglyceride Oil cauldron, 85 DEG C of dissolutions are added in 8Kg.It is down to room temperature and 1.2- hexylene glycol 0.5Kg, parahydroxyacet-ophenone 0.5Kg is added, stir evenly. Ready-made face cream has effects that moisturizing moisturizing whitening.

Claims (5)

1. a kind of combined extracts of plant whitening agent, it is characterised in that: contain mulberry root skin, the bletilla striata, Rhizoma Chuanxiong, wild marjoram, safflower, female Loyal son, turmeric, Rehmannia glutinosa, Radix Glycyrrhizae.
2. the combined extracts of plant whitening agent as described in claim 1, which is characterized in that the content of its composition is by following Mass percent composition: mulberry root skin 10%-20%, bletilla striata 10%-20%, Rhizoma Chuanxiong 5%-15%, wild marjoram 10%-20%, safflower 0.01%-0.05%, fruit of glossy privet 10%-20%, turmeric 5%-15%, Rehmannia glutinosa 10%-20%, Radix Glycyrrhizae 5%-15%.
3. a kind of extraction preparation method of such as combined extracts of plant whitening agent of any of claims 1-2, It is characterized in that, prepares as follows:
(1) by the cleaning compositions in claim 1, drying, crushing;
(2) the 1.3- propylene glycol that Extraction solvent is 70%;
(3) extraction process is ultrasonic cryogenic extraction.
4. the extraction preparation method of the combined extracts of the plant whitening agent as described in right 3, which is characterized in that it extracts special Sign is that solid-to-liquid ratio 1:3 carries out low temperature extraction, and pharmaceutical composition and 1.3- propylene glycol are mixed according to the ratio of 1:3, are 50- in temperature Under conditions of 60 DEG C, immersion 24 hours is stirred at low speed, then carries out ultrasonic extraction in 30 minutes;After extraction, coarse filtration is carried out Separation, carries out plate-type filtering afterwards, finally carries out low temperature sedimentation, final composite extract is obtained after separation.
5. the combined extracts of the plant whitening agent as described in right 1, which is characterized in that releive antianaphylactic shield applied to preparation In skin product, including facial mask, water, essence, milky lotion, cream and cleaning product, additive amount 1-3%.
CN201910182930.6A 2019-03-12 2019-03-12 A kind of combined extracts of plant whitening agent Pending CN109718184A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327273A (en) * 2019-08-06 2019-10-15 苏格格 Lightening compositions, Skin whitening care cosmetics and preparation method thereof

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CN104042516A (en) * 2014-06-26 2014-09-17 广州市络捷生物科技有限公司 Chinese herbal medicine composition with skin whitening effect as well as preparation method and application of Chinese herbal medicine composition
CN105250895A (en) * 2015-10-12 2016-01-20 王磊 Traditional Chinese medicine composition for treating lumbar vertebrae hyperosteogeny
CN106109932A (en) * 2016-07-20 2016-11-16 北京康盛源泰科技有限公司 A kind of whitening and speckle dispelling Chinese medicine composition, whitening and speckle dispelling Chinese medicine preparation, whitening and speckle dispelling facial cream, preparation method
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CN104042516A (en) * 2014-06-26 2014-09-17 广州市络捷生物科技有限公司 Chinese herbal medicine composition with skin whitening effect as well as preparation method and application of Chinese herbal medicine composition
CN105250895A (en) * 2015-10-12 2016-01-20 王磊 Traditional Chinese medicine composition for treating lumbar vertebrae hyperosteogeny
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327273A (en) * 2019-08-06 2019-10-15 苏格格 Lightening compositions, Skin whitening care cosmetics and preparation method thereof
CN110327273B (en) * 2019-08-06 2022-02-15 广州名妆化妆品制造有限公司 Whitening composition, whitening skin care product and preparation method thereof

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Application publication date: 20190507