CN109718184A - A kind of combined extracts of plant whitening agent - Google Patents
A kind of combined extracts of plant whitening agent Download PDFInfo
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- CN109718184A CN109718184A CN201910182930.6A CN201910182930A CN109718184A CN 109718184 A CN109718184 A CN 109718184A CN 201910182930 A CN201910182930 A CN 201910182930A CN 109718184 A CN109718184 A CN 109718184A
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- extraction
- combined extracts
- whitening agent
- plant whitening
- skin
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- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000008326 skin blood flow Effects 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 229930006978 terpinene Natural products 0.000 description 1
- 150000003507 terpinene derivatives Chemical class 0.000 description 1
- RBNWAMSGVWEHFP-UHFFFAOYSA-N trans-p-Menthane-1,8-diol Chemical compound CC(C)(O)C1CCC(C)(O)CC1 RBNWAMSGVWEHFP-UHFFFAOYSA-N 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 229940096998 ursolic acid Drugs 0.000 description 1
- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of combined extracts of plant whitening agent, it is the cosmetic additive agent being prepared by the raw material of following weight proportion: mulberry root skin 10%-20%, bletilla striata 10%-20%, Rhizoma Chuanxiong 5%-15%, wild marjoram 10%-20%, safflower 0.01%-0.05%, fruit of glossy privet 10%-20%, turmeric 5%-15%, Rehmannia glutinosa 10%-20%, Radix Glycyrrhizae 5%-15%.Extraction solvent of the invention: the 1.3- propylene glycol that Extraction solvent is 70%.The present invention is applied to prepare in releive antianaphylactic skin care item, including facial mask, water, essence, milky lotion, cream and cleaning product, additive amount 1-3%.
Description
Technical field
The present invention relates to a kind of combined extracts of plant whitening agent, the combination of specially a kind of plant whitening agent is extracted
Object.
Background technique
With the development and improvement of living standard of society, more and more women extremely pay close attention to the pale of skin.But
It is to be influenced by factors such as ultraviolet light irradiation, environmental pollution, endocrine disorder, heredity, causes Melanin Metabolism abnormal, melanocyte
The melanocyte of secretion increases and makes local skin blackening, pigmentation et al. body colour after generation freckle, chloasma, senile plaque and inflammation
The pigmented disease of element.Although traditional whitening active ingredients hydrogen peroxide, mercury and mercuric compounds and phenol derivatives, can reach
The effect of quick whitening, but it is with adverse reactions such as cytotoxicity, irritation, sensitizations, it is banned at present for making up
In product.Therefore, finding natural, the safe and efficient plant whitening active constituent of a new generation becomes the heat studied both at home and abroad in recent years
One of point.
Chromatodermatosis such as freckle (heredity), chloasma (incretion), sunburn (inflammatory), riel blacking
Sick (metabolic) etc. is beautiful because influencing, more and more patient's an urgent demand treatments, thus generates a large amount of whitening and freckle-removing product,
Wherein, Chinese medicine whitening product is favourably welcome with its unique advantage (safety, irritation is small, Small side effects).
The color of human skin depends on the content and distribution of melanin, and the physiology course that melanin is formed substantially can be general
It includes are as follows: melanocyte generates melanin, and melanin granule is shifted to epithelial cells by melanocyte dendritic processes, turned
The melanin granule for moving to epithelial cells goes upward to cuticula with epidermal cell and falls off and drain with cuticula.But due to by
Ultraviolet light, heredity, endocrine, the influence of inflammation and the factors such as improper diet, melanin metabolic disorder, the too fast increasing of dermal melanin
It is long and be unevenly distributed and cause local skin excessively black and pigmentation, it is sick to show as pigmentation etc. after chloasma, freckle and inflammation
Disease.During developing whitening agent, efficacy active component must have following one or more of functions: inhibit melanocyte
Proliferation;Melanin is inhibited to be formed;Melanin granule is inhibited to be transferred to epithelial cells;Accelerate in epithelial cells melanin to cuticula
Transfer;Cutin-softening layer and acceleration cuticula fall off;Extrinsic factor such as ultraviolet light, oxygen radical etc. is reduced to form melanin
The negative effect of physiology course.
Summary of the invention
The present invention provides a kind of combined extracts of plant whitening agent, it be by the raw material preparation of following weight proportion and
At cosmetic additive agent:
Mulberry root skin 10%-20%, bletilla striata 10%-20%, Rhizoma Chuanxiong 5%-15%, wild marjoram 10%-20%, safflower 0.01%-
0.05%, fruit of glossy privet 10%-20%, turmeric 5%-15%, Rehmannia glutinosa 10%-20%, Radix Glycyrrhizae 5%-15%.
Extraction solvent of the invention: the 1.3- propylene glycol that Extraction solvent is 70%.
Extracting method of the invention, ultrasonic cryogenic extraction.Particular content is as follows:
Pharmaceutical composition and 1.3- propylene glycol are mixed according to the ratio of 1:3, under conditions of temperature is 50-60 DEG C, low speed
Stirring is impregnated 24 hours, and ultrasonic extraction in 30 minutes is then carried out.After extraction, coarse filtration separation, laggard andante formula mistake are carried out
Filter finally carries out low temperature sedimentation, final composite extract is obtained after separation.
The present invention is applied to prepare releive antianaphylactic skin care item, including facial mask, water, essence, milky lotion, cream and washing
In product, additive amount 1-3%.
Mulberry root bark extract contains reduced sugar, pentosan and galactolipin acid anhydride, tannin, flavonoids etc..It can inhibit elastin laminin
Enzyme plays the role of anti-ageing;Promote the synthesis of fiber sprout cell brain amide, Palmitoleic Acid;To the Cuo because of the higher initiation of male sex hormone
Sore can prevent and treat well;There is contraction to collagenous fibres, can be used for reducing weight;There is facilitation to the activation of luciferase,
Illustrate that there is anti-inflammatory effect;The activity that can inhibit tyrosinase, has effects that whitening.
Bletilla striata extract has inhibiting effect to 5a- reductase, illustrates that extract takes off to because caused by male sex hormone is higher
Hair has good preventive and therapeutic effect, can be used for hair tonic, acne product;Bletilla striata extract or the apparent antioxidant of effect, skin
Whitening agent and anti-inflammatory agent.
Rhizoma Chuanxiong can inhibit the generation of free radical, effective scavenging activated oxygen;Under low concentration, melanin can be effectively suppressed
The activity of cell reduces the generation of melanin, but excessive concentration then shows its cytotoxic effect;There is hygroscopicity simultaneously, have
There is moisture-keeping function.
Be generally adopted by the extract of its herb in wild marjoram cosmetics, sweet wild marjoram leaf contains volatile component, as terpinene,
Terpinol, linalool, methyl chavicol, Cineole, eugenol etc.;Involatile constituent has ursolic acid, carnosic acid
Deng.Sweet wild marjoram leaf essential oil has antibiotic property, to hay bacillus, Escherichia coli, staphylococcus aureus and Streptococcus mutans, acarid etc.
There is antibacterial action.It there are no the unsafe report of external application at present, furthermore marjoram oil can be used as the fragrance of food blending.Sweet wild marjoram
It can be used as antibacterial agent, anti-mite agent, moisturizer, spectrum antioxidant, skin-whitening agents, anti-inflammatory agent etc. to extract.
Natural pigment carthamin yellow and safflower red pigment that safflower is extracted from safflower etc., safety edible are used, be can be used as
The coloring agent of the cosmetics of super quality;Safflower extract have the effects that promoting blood circulation, it is anti-inflammatory, anti-oxidant, by improve skin blood circulation,
Promote skin metabolism, remove free radical, inhibit melanin deposition, accelerate ecchymose removing decoloration, absorb ultraviolet light etc., play beauty
White, sun-proof, anti-aging function, and have therapeutic effect to contact dermatitis, seborrheic dermatitis, pruritus, neurodermatitis;
Safflower oil can be used as cosmetics oiliness raw material, the multiple nutritional components of profound level supplement skin.
The fruit of glossy privet derives from the fruit of the fruit of glossy privet, glucose, mannitol and oleanolic acid rich in etc. in extract
Multiple efficacies ingredient, can effectively clear interior free yl, and delaying skin aging improves skin health state.
Turmeric has good inhibiting effect to pityrosporum furfur, facilitates dandruff reduction, is used for anti-dandruff;To luciferase
Strong activation illustrates there is good anti-inflammatory power, can prevent and treat various dermatopathies;There is inhibition to brain amidase, thus
Maintain the amount of cortex midbrain amide, can Palmitoleic Acid can be used in conjunction with it to the inhibition of elastoser and outstanding moisture holding capacity
In conditioning skin.
Rehmannia glutinosa takes object to have facilitation to Filaggrin growth, shows play the role of enhancing skin metabolism, can change
The composition for becoming sebum can be in inhibiting oiliness, skin softening and moisturizing cosmetics in conjunction with its wettability power under low-humidity environment
With;Promotion of the glutinous rehmannia extract to cathepsin D-activity, display can control dermatitis;It can also be in weight-reducing, hair tonic and black hair product
It uses.
Proliferation function of the licorice to myocyte, the facilitation to vascular endothelial cell proliferation, to collagen-
The promotion that 4 types generate, the studies have shown thats licorice such as inhibition that NO is generated improve skin in terms of have promotion
Effect, can be used for anti-ageing cosmetics;Licorice has inhibition melanin, the effect of skin whitening simultaneously;To some bacteriums
It significantly inhibits, can be used as anti-inflammatory agent.
Specific embodiment
A kind of combined extracts of the plant whitening agent of embodiment 1;
By mulberry root skin, the bletilla striata, Rhizoma Chuanxiong, wild marjoram, safflower, the fruit of glossy privet, turmeric, Rehmannia glutinosa, Radix Glycyrrhizae.After washing, it is put into air blast
It is sufficiently dry in drying box.
Weigh dry mulberry root skin 300g, bletilla striata 300g, Rhizoma Chuanxiong 200g, wild marjoram 300g, safflower 0.1g, fruit of glossy privet 300g,
Turmeric 200g, Rehmannia glutinosa 300g, Radix Glycyrrhizae 200g.
It crushes.
The Chinese herbal medicine of crushing is put into constant temperature extracting tank.
70%1.3- propylene glycol 2.1KG is added, temperature maintains 55 DEG C, is slowly stirred, and impregnates 8 hours.
After immersion, progress ultrasonic extraction, interrupted extraction 30 minutes.
It is filtered with plate filter, is put into cryopreservation tank and is settled, settled 72 hours, take the supernatant to be
Finished product.
A kind of application of the combined extracts of the plant whitening agent of embodiment 2 in facial mask
The constituent and content (%) of facial mask are as follows:
The combined extracts of plant whitening agent: 1
Water: 92.55
Glycerol: 3
EDTA:0.05
Sodium Hyaluronate: 0.05
Xanthan gum: 0.1
Carbomer: 0.15
Glycine betaine: 1.5
Arginine: 0.12
1.2- hexylene glycol: 0.5
Parahydroxyacet-ophenone: 0.5
Facial mask the preparation method is as follows:
By the combined extracts 1Kg of plant whitening agent, water 92.55Kg, glycerol 3Kg, EDTA 0.05Kg, Sodium Hyaluronate
0.05Kg, xanthan gum 0.1Kg, carbomer 0.15Kg, glycine betaine 1.5Kg are put into kettle, are heated to 85 DEG C, are stirred 30 minutes,
It homogeneous 3 minutes, is uniformly dispersed.
40 DEG C of addition arginine 0.12Kg are cooled to, are stirred evenly.
It is down to room temperature and 1.2- hexylene glycol 0.5Kg, parahydroxyacet-ophenone 0.5Kg is added, stir evenly.
Film cloth is added, so that it may as people's natural whitening mask used in everyday in ready-made facial mask essence.
A kind of application of the combined extracts of the plant whitening agent of embodiment 3 in frost
The constituent and content (%) of frost are as follows:
The combined extracts of plant whitening agent: 2
Water: 81.9
Glycerol: 3
EDTA:0.05
Sodium Hyaluronate: 0.05
Acrylamide dimethyltaurine ammonium/VP copolymer: 1
Glycine betaine: 1.5
The smooth olive oleate of cetearyl glucoside, sorb, cetostearyl alcohol: 1.5
Caprylic/capric triglyceride: 8
1.2- hexylene glycol: 0.5
Parahydroxyacet-ophenone: 0.5
Frost the preparation method is as follows:
By the combined extracts 2Kg, water 80.9Kg, glycerol 3Kg, EDTA0.05Kg, Sodium Hyaluronate of plant whitening agent
0.05Kg, acrylamide dimethyltaurine ammonium/VP copolymer 1 Kg, glycine betaine 1.5Kg are put into emulsion pot, are heated to 85 DEG C,
Stirring 30 minutes, homogeneous 3 minutes, is uniformly dispersed.
By cetearyl glucoside, the smooth olive oleate of sorb, cetostearyl alcohol 1.5Kg, caprylic/capric triglyceride
Oil cauldron, 85 DEG C of dissolutions are added in 8Kg.It is down to room temperature and 1.2- hexylene glycol 0.5Kg, parahydroxyacet-ophenone 0.5Kg is added, stir evenly.
Ready-made face cream has effects that moisturizing moisturizing whitening.
Claims (5)
1. a kind of combined extracts of plant whitening agent, it is characterised in that: contain mulberry root skin, the bletilla striata, Rhizoma Chuanxiong, wild marjoram, safflower, female
Loyal son, turmeric, Rehmannia glutinosa, Radix Glycyrrhizae.
2. the combined extracts of plant whitening agent as described in claim 1, which is characterized in that the content of its composition is by following
Mass percent composition: mulberry root skin 10%-20%, bletilla striata 10%-20%, Rhizoma Chuanxiong 5%-15%, wild marjoram 10%-20%, safflower
0.01%-0.05%, fruit of glossy privet 10%-20%, turmeric 5%-15%, Rehmannia glutinosa 10%-20%, Radix Glycyrrhizae 5%-15%.
3. a kind of extraction preparation method of such as combined extracts of plant whitening agent of any of claims 1-2,
It is characterized in that, prepares as follows:
(1) by the cleaning compositions in claim 1, drying, crushing;
(2) the 1.3- propylene glycol that Extraction solvent is 70%;
(3) extraction process is ultrasonic cryogenic extraction.
4. the extraction preparation method of the combined extracts of the plant whitening agent as described in right 3, which is characterized in that it extracts special
Sign is that solid-to-liquid ratio 1:3 carries out low temperature extraction, and pharmaceutical composition and 1.3- propylene glycol are mixed according to the ratio of 1:3, are 50- in temperature
Under conditions of 60 DEG C, immersion 24 hours is stirred at low speed, then carries out ultrasonic extraction in 30 minutes;After extraction, coarse filtration is carried out
Separation, carries out plate-type filtering afterwards, finally carries out low temperature sedimentation, final composite extract is obtained after separation.
5. the combined extracts of the plant whitening agent as described in right 1, which is characterized in that releive antianaphylactic shield applied to preparation
In skin product, including facial mask, water, essence, milky lotion, cream and cleaning product, additive amount 1-3%.
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