CN109633019A - 一种脂肪乳注射液中添加剂的检测方法 - Google Patents
一种脂肪乳注射液中添加剂的检测方法 Download PDFInfo
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- CN109633019A CN109633019A CN201811644358.2A CN201811644358A CN109633019A CN 109633019 A CN109633019 A CN 109633019A CN 201811644358 A CN201811644358 A CN 201811644358A CN 109633019 A CN109633019 A CN 109633019A
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- 239000012224 working solution Substances 0.000 claims abstract description 41
- 239000012488 sample solution Substances 0.000 claims abstract description 38
- 239000013558 reference substance Substances 0.000 claims abstract description 32
- 238000012360 testing method Methods 0.000 claims abstract description 28
- 238000004811 liquid chromatography Methods 0.000 claims abstract description 19
- 239000012086 standard solution Substances 0.000 claims abstract description 17
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- 238000010200 validation analysis Methods 0.000 claims abstract description 16
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 105
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- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 24
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- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims description 12
- 235000019253 formic acid Nutrition 0.000 claims description 12
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- 229910052760 oxygen Inorganic materials 0.000 description 9
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- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
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- 229920000642 polymer Polymers 0.000 description 1
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N2030/042—Standards
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
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- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
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CN201811644358.2A CN109633019B (zh) | 2018-12-29 | 2018-12-29 | 一种脂肪乳注射液中添加剂的检测方法 |
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CN201811644358.2A CN109633019B (zh) | 2018-12-29 | 2018-12-29 | 一种脂肪乳注射液中添加剂的检测方法 |
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CN109633019A true CN109633019A (zh) | 2019-04-16 |
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1614413A (zh) * | 2004-11-26 | 2005-05-11 | 南京大学 | 抗氧剂168及其杂质的高效液相色谱分析法 |
CN106916410A (zh) * | 2017-04-11 | 2017-07-04 | 东莞出入境检验检疫局检验检疫综合技术中心 | Abs塑料中双酚a和壬基酚标准样品及其制备方法 |
CN108120787A (zh) * | 2017-12-21 | 2018-06-05 | 上海微谱化工技术服务有限公司 | 聚烯烃中抗氧剂的定性定量方法 |
CN109061014A (zh) * | 2018-10-29 | 2018-12-21 | 上海金发科技发展有限公司 | 一种树脂组合物中抗氧剂168及其氧化物含量测方法及应用 |
-
2018
- 2018-12-29 CN CN201811644358.2A patent/CN109633019B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1614413A (zh) * | 2004-11-26 | 2005-05-11 | 南京大学 | 抗氧剂168及其杂质的高效液相色谱分析法 |
CN106916410A (zh) * | 2017-04-11 | 2017-07-04 | 东莞出入境检验检疫局检验检疫综合技术中心 | Abs塑料中双酚a和壬基酚标准样品及其制备方法 |
CN108120787A (zh) * | 2017-12-21 | 2018-06-05 | 上海微谱化工技术服务有限公司 | 聚烯烃中抗氧剂的定性定量方法 |
CN109061014A (zh) * | 2018-10-29 | 2018-12-21 | 上海金发科技发展有限公司 | 一种树脂组合物中抗氧剂168及其氧化物含量测方法及应用 |
Non-Patent Citations (4)
Title |
---|
YALI GAO ET AL: "Determination of Polymer Additives− Antioxidants and Ultraviolet (UV) Absorbers by High-Performance Liquid Chromatography Coupled with UV Photodiode Array Detection in Food Simulants", 《JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY》 * |
朱碧君 等: "HPLC法测定聚丙烯输液瓶中抗氧剂1010、抗氧剂1076、抗氧剂168、抗氧剂330的含量", 《药物分析杂志》 * |
李兴春 等: "HPLC 法测定高密度聚乙烯桶包装血液透析浓缩液中抗氧剂1010、抗氧剂330、抗氧剂1076、抗氧剂168的含量", 《药学研究》 * |
谢新艺 等: "液相色谱法测定一次性使用聚烯烃输液器中抗氧剂在紫杉醇注射液中的溶出", 《中国医疗器械信息》 * |
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Address after: 200438 room 110, No.2, Lane 139, Guowei Road, Yangpu District, Shanghai Patentee after: Shanghai microspectrum Testing Technology Group Co.,Ltd. Address before: 200000 1st floor, building 9, 135 Guowei Road, Yangpu District, Shanghai Patentee before: SHANGHAI MICROSPECTRUM CHEMICAL TECHNOLOGY SERVICE Co.,Ltd. |
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Effective date of registration: 20230109 Address after: 200438 room 110, No.2, Lane 139, Guowei Road, Yangpu District, Shanghai Patentee after: Shanghai microspectrum Testing Technology Group Co.,Ltd. Patentee after: Shanghai Chuanghua Material Technology Co.,Ltd. Address before: 200438 room 110, No.2, Lane 139, Guowei Road, Yangpu District, Shanghai Patentee before: Shanghai microspectrum Testing Technology Group Co.,Ltd. |
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Address after: 200438 room 110, No.2, Lane 139, Guowei Road, Yangpu District, Shanghai Patentee after: Shanghai microspectrum Testing Technology Group Co.,Ltd. Patentee after: Shanghai Chuanghua Technology Service Co.,Ltd. Address before: 200438 room 110, No.2, Lane 139, Guowei Road, Yangpu District, Shanghai Patentee before: Shanghai microspectrum Testing Technology Group Co.,Ltd. Patentee before: Shanghai Chuanghua Material Technology Co.,Ltd. |