CN109481326A - A kind of after-sun recovery Essence - Google Patents
A kind of after-sun recovery Essence Download PDFInfo
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- CN109481326A CN109481326A CN201811375191.4A CN201811375191A CN109481326A CN 109481326 A CN109481326 A CN 109481326A CN 201811375191 A CN201811375191 A CN 201811375191A CN 109481326 A CN109481326 A CN 109481326A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The present invention relates to daily chemical product technical fields, and in particular to a kind of after-sun recovery Essence.It includes moisturizer 3.0-40.0%, thickener 0.1-15.0%, emollient 0.1-5.0%, active additive 0.1-15.0%, auxiliary agent 0.1-5.0%, water surplus that the present invention, which repairs Essence,.Moisturizer, thickener in after-sun recovery Essence of the invention, emollient can be penetrated into effectively in skin, play good maintenance effect to skin, securely and reliably, easily be absorbed；Active additive is by identifying and combining the specific receptor of skin immune cells to have extremely significant prevention and adjustment effect of releiving for cutaneous anaphylaxis caused by due to immune system excessive response；Skin barrier function can be enhanced, skin is helped to fight the aging of day ordinary light, prevent skin sunburn, improve the inflammation occurred after skin shines and repair damage.
Description
Technical field
The present invention relates to daily chemical product technical fields, and in particular to a kind of after-sun recovery Essence.
Background technique
After ultraviolet light irradiation cortex forms the sunburn phenomenons such as color spot, colour of skin unevenness or decortication, most people is expected with beauty
White product improves the compromise state of skin, but most important not instead of whitening after actually tanning severely, and should alleviate skin first
The symptom of skin water shortage carries out after-sun recovery.
After-sun recovery product on the market has many dosage forms, including water, cream, frost, essence, facial mask etc..These skin nursings
Effect substance in product is plant extracts mostly, is lack of pertinence to after-sun recovery；There are also joined polypeptides matter,
But the polypeptide being added is expensive, and at high cost, often additional amount is few in the product of same price, takes effect relatively slow；Add there are also some
Chemical industry synthesis substance is entered, although quick, safety is often lower.
Schizophyllan is a kind of water-soluble neutral exocellular polysaccharide, a variety of containing beta glucan, malic acid, calcium, selenium etc.
Effective component is rich in β -1,3 glycosidic bonds.There are no use schizophyllans as after-sun recovery effect substance on the market at present.
Summary of the invention
The object of the present invention is to provide a kind of after-sun recovery Essences.Essence quality of the invention does not stick mildly clearly
It is greasy, it can be used with repeated multiple times large dosage, not will cause the adverse effects such as allergic stimulated and thick and heavy, peeling and skin is born
Load；Essence of the invention is resisted extraneous by scavenging capacity oxygen radical, raising immunity of organisms, enhancing skin barrier function
Stimulation；By inhibiting the raising of sensitization lgE immunoglobulin, impaired mast cell and basophilla mitochondrial are repaired, is inhibited
Release with histamine is reduced, reduces the expression of inflammatory factor；The moisturizer of after-sun recovery Essence selection of the invention, thickening
Agent, active additive and auxiliary agent can be penetrated into effectively in skin, play good maintenance effect, and safety to skin
It is high.
The present invention is achieved by the following technical solutions:
A kind of after-sun recovery Essence, which is characterized in that including following components by weight percentage:
Preferably, the moisturizer is selected from glycerol, butanediol, propylene glycol, dipropylene glycol, sorbierite, mannitol, beet
Alkali, Sodium Hyaluronate, algal polysaccharides, glucan, biological carbohydrate gum -1, glyceryl acrylate/acrylic copolymer, PVM/MA copolymerization
One of object is a variety of.
It is further preferred that the moisturizer is combined by macromolecular substances and small-molecule substance, the small-molecule substance choosing
From one of glycerol, butanediol, propylene glycol or a variety of, dosage 5-20%；The macromolecular substances are Sodium Hyaluronate, are used
Amount is 0.01-0.05%.The moisturizer combination that the present invention selects has good moistening effect, while not will cause skin not
Suitable sense.
Preferably, the thickener hydroxyethyl cellulose, hydroxypropyl methyl cellulose, polyacrylate cross-linked polymer-
6, one of xanthan gum, gellan gum, carbomer, Sodium Polyacrylate, polyacrylamide, glycerine polyacrylate or a variety of.This
The thickener that invention is selected not only has good thickening capabilities, additionally it is possible to provide prolonged comfortable moisturizing effect to skin.Separately
Outside, thickener has splendid water solubility, water-retaining property and lubrication property, and good with active additive compatibility.
It is further preferred that the thickener is glycerine polyacrylate.
Preferably, the emollient is selected from PEG-7 glyceryl cocoate, Jojoba wax PEG-120 esters, double-PEG-15
One of methyl ether dimethicone is a variety of.In the present invention, emollient, which rises to moisten and supplement the nutrients, repairs barrier
Function.
It is further preferred that the emollient is Jojoba wax PEG-120 esters, with fabulous permeability and sprawl
Property, skin barrier function can be improved.
Preferably, the active additive is selected from schizophyllan, beta glucan, yeast extract, oligopeptides, carnosine, collagen
One of albumen, aloe extract are a variety of.The active additive that the present invention selects, by identifying and combining cutaneous immunisation thin
The specific receptor of born of the same parents, for cutaneous anaphylaxis caused by due to immune system excessive response, with extremely significant prevention and
It releives adjustment effect, such as reduced erythema index, repairing the skin injury as caused by ultraviolet radioactive, quickly repair and be burned skin
Skin and improvement scytitis；Skin barrier function can be enhanced, help skin to fight the aging of day ordinary light, prevent skin sunburn, improved
The inflammation that occurs and damage is repaired after skin shines.
It is further preferred that the active additive is schizophyllan.
Preferably, the auxiliary agent is selected from one of preservative, aromatic, pH adjusting agent, anti-sensitive agent or a variety of.
It is further preferred that the preservative is selected from Phenoxyethanol, pentanediol, pungent glycol, hexylene glycol, para hydroxybenzene second
Ketone, decoyl hydroximic acid, benzoic acid and its salt, salicylic acid and its salt, sorbic acid and its salt it is one or more.
It is further preferred that the anti-sensitive agent be selected from dipotassium glycyrrhizinate, bisabolol, purslane extract, allantoin,
It is Tetrandrine, Herba polygoni hydropiperis extract, Radix Cynanchi Atrati extract, one or more in Folium Artemisiae Argyi extract.
It is further preferred that the aromatic is fragrance of a flower aromatic, fruity aromatic, flowers and fruits perfume (or spice) aromatic, radix aucklandiae fragrance
One of agent is a variety of.
It is further preferred that the pH adjusting agent is selected from aminomethyl propanol, sodium hydroxide, potassium hydroxide, arginine, three second
It is hydramine, citric acid, one or more in sodium citrate.When obtained Essence pH is 5.0-8.0, preferably 5.5-6.5, then
Without adjusting the pH value of Essence.
Beneficial effects of the present invention:
(1) moisturizer in after-sun recovery Essence of the invention, thickener, emollient are mainly derived from plant, can
It effectively penetrates into skin, good maintenance effect is played to skin, securely and reliably, easily absorb.
(2) active additive that the present invention selects, by identifying and combining the specific receptor of skin immune cells, for
Cutaneous anaphylaxis caused by due to immune system excessive response has extremely significant prevention and adjustment effect of releiving, such as reduces
Erythema index, reparation skin injury as caused by ultraviolet radioactive, quickly reparation is burned skin and improves scytitis；Energy
Enhance skin barrier function, skin is helped to fight the aging of day ordinary light, prevent skin sunburn, improves the inflammation occurred after skin shines simultaneously
Repair damage.
Detailed description of the invention
Fig. 1 is the skin before the product of subject's embodiment 1 on probation；
Fig. 2 is the skin after the product of subject's embodiment 1 on probation.
Specific embodiment
With reference to embodiments, the invention will be further described.
Embodiment 1
A kind of after-sun recovery Essence, including following components by weight percentage:
Contrast test:
30 subject's left and right arms compare A sample and C sample, B sample and C sample respectively, in which: A sample is embodiment 1
Product；B sample is the product for removing schizophyllan in embodiment 1, and C sample is pure water.
Test method: the period (1 point to 3 points of afternoon) of direct sunlight is selected；Each 2g of A, B sample is taken, on left and right arms
The skin area of equal areas size smoothens A, B sample respectively, and massage is until absorb；In order to carry out blank control, on left and right arms
The remaining skin area with spread product homalographic size is stayed to smear C；Arm is exposed under daylight 30 minutes using after sample；
Each region sunburn (erythema index, light aging) situation of comparison left and right arms A/B/C, counts score, wherein 1 point is tanned severely to be obvious, 2 points
Slightly to tan severely, 3 points are no sunburn.As a result it is listed in Table 1:
1 contrast test result of table
| Score value number | A | B | C |
| 1 point | 1 | 6 | 11 people |
| 2 points | 12 | 14 | 15 people |
| 3 points | 17 | 10 | 4 people |
| Average | 2.9 | 2.1 | 1.8 |
As can be seen from the above table, the product of embodiment 1 has the effect of obviously anti-sunburn, is not adding schizophyllan
When, product still has certain protection effect.This is because the present invention is cooperateed with again using moisturizer, emollient and thickener
Match, there is good moisturizing moisturizing effect, slow down skin to a certain extent and tanned severely.And schizophyllan is added, hence it is evident that shine
The number of wound greatly reduces, and shows that schizophyllan can preferably cooperate with compounding with moisturizer, emollient and thickener, thus
Make Essence of the invention that there is extraordinary effect.
Embodiment 2
A kind of after-sun recovery Essence, including following components by weight percentage:
Test result:
After 30 subjects continuously try out product 28 days of embodiment 2, feedback score is shown in Table 2.
Test method: volunteer totally 30 tanned severely in various degree are selected；After subject per's face cleaning, Example 2
Product 2g extends along skin pattern in the palm of the hand, is uniformly applied to face and neck, is pressed lightly on palm to absorption, is repeated
The step is until product is absorbed by the skin；It is daily to use 2 times (once in the morning and once at night), it is used continuously 28, statistics subject's scoring.
Wherein, 1 point is that product is very poor, there is sense of discomfort after；2 points, obviously not feel, are experienced poor；3 points general for effect；4 points
To there is better effects；5 points are fine for effect, are as a result listed in Table 2:
2 subject feedback of table, which scores, to be counted
| Option | Score value | Number | Ratio % |
| Effect is fine | 5 | 9 | 30.0 |
| There are better effects | 4 | 15 | 50.0 |
| Effect is general | 3 | 5 | 16.7 |
| Obviously do not feel | 2 | 1 | 3.3 |
| Product is poor, is not suitable for | 1 | 0 | 0 |
After product 4 weeks of embodiment 2 are used continuously, through subject feedback, it is believed that product has certain effect or effect fine
Account for 80%, it is believed that effect is general to account for 16.7%, after experience without obviously feel account for 3.3%.In addition, comparison subject is on probation
The front and back colour of skin and face texture show after product 4 weeks of embodiment 2 are used continuously that the cheek colour of skin and texture are obviously improved.As a result
Show that reparation Essence of the invention can play good reparation and maintenance effect to skin.
Embodiment 3
A kind of after-sun recovery Essence, including following components by weight percentage:
Test result:
After 30 subjects continuously try out product 7 days of embodiment 3, feedback score is shown in Table 3.
Test method: select the volunteer of sensitive skin (have allergies, easy allergy or allergy is not restored) total
30；After subject per's face cleaning, takes 2g product in the palm of the hand, extend along skin pattern, be uniformly applied to face and neck, use
Palm is pressed lightly on to absorption, repeats the step until product is absorbed by the skin；Daily using 2 times (once in the morning and once at night), continuously
Using 7 days, statistics subject's scoring.Wherein, 1 point of allergy or more serious；2 points, obviously not feel, also obviously do not imitate
Fruit；3 points are to feel comfortable, and effect is general；4 points are to have better effects；5 points are fine for effect, are as a result listed in Table 3:
3 subject feedback of table, which scores, to be counted
| Option | Score value | Number | Ratio % |
| Effect is fine | 5 | 7 | 23.3 |
| There are better effects | 4 | 16 | 53.3 |
| Effect is general | 3 | 5 | 16.7 |
| Obviously do not feel | 2 | 2 | 6.7 |
| Allergy is more serious | 1 | 0 | 0 |
Compare subject front and back face red capillary, erythema index, sensitive situations and anti-anaphylaxis effect on probation.It is anti-through subject
Feedback, it is believed that product has certain effect or effect preferably to account for 86.6%, it is believed that actual effect fruit is general to account for 16.7%.It is mainly reflected in
Red capillary, erythema index, safety even anti-anaphylaxis effect can be significantly reduced.The result shows that reparation Essence of the invention can
Good reparation and antiallergic effect are played to skin.
Above is only a specific embodiment of the present invention, it is not intended to limit the scope of the invention, all utilizations
The equivalent transformation that the present invention makees, is applied directly or indirectly in other relevant technical fields, similarly includes of the invention
Among scope of patent protection.
Claims (9)
1. a kind of after-sun recovery Essence, which is characterized in that including following components by weight percentage:
2. after-sun recovery Essence according to claim 1, which is characterized in that the moisturizer be selected from glycerol, butanediol,
Propylene glycol, dipropylene glycol, sorbierite, mannitol, glycine betaine, Sodium Hyaluronate, algal polysaccharides, glucan, biological carbohydrate gum -1,
One of glyceryl acrylate/acrylic copolymer, Gantrez AN-119 are a variety of.
3. after-sun recovery Essence according to claim 1, which is characterized in that the thickener is selected from hydroxy ethyl fiber
Element, polyacrylate cross-linked polymer -6, xanthan gum, gellan gum, carbomer, Sodium Polyacrylate, gathers at hydroxypropyl methyl cellulose
One of acrylamide, glycerine polyacrylate are a variety of.
4. after-sun recovery Essence according to claim 1, which is characterized in that the emollient is selected from PEG-7 glycerol coconut palm
One of oleate, Jojoba wax PEG-120 esters, double-PEG-15 methyl ether dimethicones are a variety of.
5. after-sun recovery Essence according to claim 1, which is characterized in that the active additive, which is selected from, splits pleat bacterium
One of element, beta glucan, yeast extract, oligopeptides, carnosine, collagen, aloe extract are a variety of.
6. after-sun recovery Essence according to claim 5, which is characterized in that the active additive is schizophyllan.
7. after-sun recovery Essence according to claim 1, which is characterized in that the auxiliary agent is selected from preservative, antiallergic sense
One of agent, aromatic, pH adjusting agent are a variety of.
8. after-sun recovery Essence according to claim 7, which is characterized in that the anti-sensitive agent is selected from glycyrrhizic acid two
Potassium, bisabolol, purslane extract, allantoin, Tetrandrine, Herba polygoni hydropiperis extract, Radix Cynanchi Atrati extract, in Folium Artemisiae Argyi extract
It is one or more.
9. the purposes of after-sun recovery Essence of any of claims 1-8, which is characterized in that the Essence is used for
Erythema index is reduced, skin sunburn is prevented, repairs the skin injury as caused by ultraviolet radioactive, repair skin barrier, is quick
It repairs scald skin and improves scytitis.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811375191.4A CN109481326A (en) | 2018-11-19 | 2018-11-19 | A kind of after-sun recovery Essence |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811375191.4A CN109481326A (en) | 2018-11-19 | 2018-11-19 | A kind of after-sun recovery Essence |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279638A (en) * | 2019-07-11 | 2019-09-27 | 浙江康满家日用品有限公司 | A kind of reparation skin skin care compositions and preparation method thereof |
| CN110339083A (en) * | 2019-08-21 | 2019-10-18 | 广东一华科技有限公司 | A kind of oligopeptides repairs Essence and its application method |
| CN110680789A (en) * | 2019-11-22 | 2020-01-14 | 成都珂萝瑞诗化妆品有限公司 | After-sun repair mask and preparation method thereof |
| CN111150700A (en) * | 2020-03-11 | 2020-05-15 | 广州市逸轩精细化工有限公司 | Hormone face-repairing essence cream and preparation method thereof |
| CN111214429A (en) * | 2020-03-11 | 2020-06-02 | 广州市逸轩精细化工有限公司 | Repair essence and preparation method thereof |
| CN111265445A (en) * | 2020-03-25 | 2020-06-12 | 配方化妆品科技(广州)有限公司 | Light sensation whitening essence and preparation method thereof |
| CN111450013A (en) * | 2020-05-12 | 2020-07-28 | 广州怡嘉生物科技有限公司 | Repairing stock solution |
| CN112315883A (en) * | 2020-11-24 | 2021-02-05 | 哈尔滨敷尔佳科技发展有限公司 | Skin care composition for controlling oil and removing acne and preparation and application thereof |
| CN113633563A (en) * | 2021-08-12 | 2021-11-12 | 广州市中科医美生物科技有限公司 | Ecological sun-proof light-permeable isolation repairing emulsion and preparation method thereof |
| CN114767568A (en) * | 2022-05-06 | 2022-07-22 | 天津翀嚞管理咨询有限公司 | Repairing liquid containing oligopeptide component and preparation method and application thereof |
| CN115475274A (en) * | 2022-10-14 | 2022-12-16 | 云飞生物药业(吉林)有限公司 | Skin repair dressing |
| CN116003577A (en) * | 2023-02-14 | 2023-04-25 | 广东丸美生物技术股份有限公司 | Recombinant collagen for skin soothing and repairing and application thereof |
| CN116966117A (en) * | 2023-08-21 | 2023-10-31 | 广州君奕科技有限公司 | Sun-screening composition and preparation method and application thereof |
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