CN109451729B - 工程化病毒载体减少了炎症和免疫反应的诱导 - Google Patents
工程化病毒载体减少了炎症和免疫反应的诱导 Download PDFInfo
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- CN109451729B CN109451729B CN201780045910.3A CN201780045910A CN109451729B CN 109451729 B CN109451729 B CN 109451729B CN 201780045910 A CN201780045910 A CN 201780045910A CN 109451729 B CN109451729 B CN 109451729B
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210208639.3A CN114807152A (zh) | 2016-06-08 | 2017-06-08 | 工程化病毒载体减少了炎症和免疫反应的诱导 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662347302P | 2016-06-08 | 2016-06-08 | |
| US62/347,302 | 2016-06-08 | ||
| PCT/US2017/036525 WO2017214378A1 (en) | 2016-06-08 | 2017-06-08 | Engineered viral vector reduces induction of inflammatory and immune responses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210208639.3A Division CN114807152A (zh) | 2016-06-08 | 2017-06-08 | 工程化病毒载体减少了炎症和免疫反应的诱导 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109451729A CN109451729A (zh) | 2019-03-08 |
| CN109451729B true CN109451729B (zh) | 2022-03-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780045910.3A Active CN109451729B (zh) | 2016-06-08 | 2017-06-08 | 工程化病毒载体减少了炎症和免疫反应的诱导 |
| CN202210208639.3A Pending CN114807152A (zh) | 2016-06-08 | 2017-06-08 | 工程化病毒载体减少了炎症和免疫反应的诱导 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202210208639.3A Pending CN114807152A (zh) | 2016-06-08 | 2017-06-08 | 工程化病毒载体减少了炎症和免疫反应的诱导 |
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| Country | Link |
|---|---|
| US (3) | US11339396B2 (enExample) |
| EP (1) | EP3468605A4 (enExample) |
| JP (2) | JP7034951B2 (enExample) |
| KR (1) | KR20190017872A (enExample) |
| CN (2) | CN109451729B (enExample) |
| AU (2) | AU2017277647B2 (enExample) |
| WO (1) | WO2017214378A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP7034951B2 (ja) | 2016-06-08 | 2022-03-14 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 操作されたウイルスベクターは炎症および免疫応答の誘導を低減する |
| EP3707262A1 (en) * | 2017-11-08 | 2020-09-16 | President and Fellows of Harvard College | Compositions and methods for inhibiting viral vector-induced inflammatory responses |
| US10736957B2 (en) * | 2017-12-19 | 2020-08-11 | President And Fellows Of Harvard College | Enhanced immunogenicity of mRNA with co-encoded adjuvant sequences |
| WO2020154645A1 (en) * | 2019-01-24 | 2020-07-30 | Generation Bio Co. | Close-ended dna (cedna) and use in methods of reducing gene or nucleic acid therapy related immune response |
| US11608491B2 (en) | 2019-02-22 | 2023-03-21 | Life Technologies Corporation | Suspension system for adeno associated virus production |
| US20220259599A1 (en) * | 2019-05-15 | 2022-08-18 | President And Fellows Of Harvard College | Compositions and methods for inhibiting nucleic acid vector-induced inflammatory responses |
| AU2021232069A1 (en) * | 2020-03-05 | 2022-11-03 | Flagship Pioneering Innovations Vi, Llc | Host defense suppressing methods and compositions for modulating a genome |
| EP4301860A1 (en) * | 2021-03-04 | 2024-01-10 | Kriya Therapeutics, Inc. | Viral vector constructs incorporating dna for inhibiting toll like receptors and methods of using the same |
| WO2025087987A1 (en) * | 2023-10-23 | 2025-05-01 | Sartorius Stedim Cellca Gmbh | Plasmids for improved aav titers and empty full ratios |
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Also Published As
| Publication number | Publication date |
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| CN109451729A (zh) | 2019-03-08 |
| CN114807152A (zh) | 2022-07-29 |
| JP2019517266A (ja) | 2019-06-24 |
| US11339396B2 (en) | 2022-05-24 |
| JP7394898B2 (ja) | 2023-12-08 |
| WO2017214378A1 (en) | 2017-12-14 |
| AU2023251424A1 (en) | 2023-11-09 |
| US20240043849A1 (en) | 2024-02-08 |
| AU2017277647B2 (en) | 2023-07-27 |
| AU2017277647A1 (en) | 2018-12-13 |
| US20190177731A1 (en) | 2019-06-13 |
| JP2022066336A (ja) | 2022-04-28 |
| JP7034951B2 (ja) | 2022-03-14 |
| US20190316151A1 (en) | 2019-10-17 |
| EP3468605A1 (en) | 2019-04-17 |
| EP3468605A4 (en) | 2020-01-08 |
| KR20190017872A (ko) | 2019-02-20 |
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