CN109418270A - A kind of bactericidal composition of fluorine-containing phenylate amide - Google Patents
A kind of bactericidal composition of fluorine-containing phenylate amide Download PDFInfo
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N39/00—Biocides, pest repellants or attractants, or plant growth regulators containing aryloxy- or arylthio-aliphatic or cycloaliphatic compounds, containing the group or, e.g. phenoxyethylamine, phenylthio-acetonitrile, phenoxyacetone
- A01N39/02—Aryloxy-carboxylic acids; Derivatives thereof
- A01N39/04—Aryloxy-acetic acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
- A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
- A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
Abstract
The invention discloses a kind of bactericidal compositions containing two kinds of active components, the first active constituent is fluorobenzene ether amide, second active ingredient is selected from one of Isoprothiolane, tricyclazole, fenoxanil, Prochloraz, tiadinil and isotianil, two or three of combination of the above, and the mass ratio of two kinds of active components is 20:1~1:20.Composition provided by the invention is suitable for agricultural bactericidal, particularly suitable for preventing and treating rice blast.
Description
Technical field
The invention belongs to composition pesticide fields, and in particular to a kind of for preventing and treating the bactericidal composition of rice blast.
Background technique
Rice blast is one of most destructive disease and global fungal disease in Rice Production, in entire water
In the period of rice growth, generally occur in nearly all producing region；Especially in thermophilic, the climate zone at cloudy day and high humility, rice blast
Occur frequent.It often results in and drops in production over a large area when rice blast is very popular, or even total crop failure in flakes, while largely effecting on yield and crop
Quality a, it has also become outstanding problem of rice high yield stable yields.
In the real process of agricultural production, the problem of controlling disease most easily produces is the generation of germ drug resistance.No
The kind ingredient of same-action mechanism is compounded, and is to prevent and treat the very common method of resistance germ.Rice blast prevention and treatment at present is upper main
The medicaments such as Isoprothiolane, tricyclazole are relied on, such as:
(1) Isoprothiolane (Isoprothiolane), chemical name: 1,3- dithiolane -2- subunit Diisopropyl malonate.
By inhibiting the formation of cellulase, and prevent the further growth of mycelia.There is preventive and therapeutic action to rice blast, it can
By each site absorption of rice, and accumulates and arrive leaf portion tissue, so that drug effect is played, resistance of rainwater washing against；
(2) tricyclazole (Tricyclazole), chemical name: 5- methyl one 1,2,4 one triazol (3,4-b) [1,3] benzene
And thiazole.Tricyclazole is prevention and treatment rice blast bactericide specially, and bactericidal effect mechanism is mainly to inhibit the formation of attachment spore melanin,
To inhibit spore germination and attachment spore to be formed, prevents germ from invading people and reduce the generation of magnaporthe grisea spore；
(3) fenoxanil (Dimethomorph), chemical name: N- (1- itrile group -1,2- dimethyl propyl) -2- (2,4-
Dichlorophenoxy) propionamide.Fenoxanil category benzene oxanamide class fungicide is one novel for preventing and treating rice blast
Systemic fungicide belongs to melanin biosynthesis inhibitor, is mainly used for preventing and treating rice blast, including leaf Wen is He Miho pest；
(4) Prochloraz (Prochloraz), chemical name: N- propyl-N- [2- (2,4,6- Trichlorophenoxy) ethyl]-miaow
Azoles -1- formamide.By inhibit sterol biosynthesis work, no systemic action but have certain conductibility, for
Multiple diseases preventive effect caused by sac fungus and Fungi Imperfecti is splendid；
(5) tiadinil (Tiadinil), chemical name: 3 '-chloro- 4 ', 4 '-dimethyl -1,2,3- thiadiazoles -5- formyl
Aniline.Tiadinil belongs to thiadiazoles acid amide fungicides, and the mechanism of action is mainly that germ mycelia is prevented to invade neighbouring be good for
Health cell, and can induce generation disease-resistant gene is mainly used for rice field prevention and treatment rice blast, which has good absorbability, can be with
By root absorption, and it is transmitted to other positions rapidly, is suitable for the water surface and uses, the lasting period is long, all to leaf blast in rice and ear stem pest
There is preferable control efficiency；
(6) isotianil (Isotianil), chemical name: N- (2,6- xylyl)-N- (2- methoxyacetyl)-DL-
Aminopropanoate.Isotianil (isotianil) is that Bayer and Sumitomo Chemical research and develop the different thiophene for being used to prevent and treat rice blast jointly
Azoles fungicide.Its feature is that it can't generate direct antibacterial action to pathogen, but certainly by excitation rice
Body achievees the purpose that the natural immunology defense of rice blast to resist rice blast.
It is increasing that dose is administered alone because control efficiency, which is used for a long time, to be reduced in above-mentioned medicament.Medicament is a large amount of simultaneously
Using increasing pesticide residue.Food safety is endangered, environmental pollution is aggravated.It therefore will by the bactericide compounded of different role mechanism
It is science, the development need of the rational use of medicines.
Fluorobenzene ether amide is the amides compound of Chinese patent CN104557709 report, and structural formula is as follows:
It is effective in prevention and treatment rice sheath blight disease and powdery mildew of cucumber.
In the prior art, there are not fluorobenzene ether amide and Isoprothiolane, tricyclazole, fenoxanil, Prochloraz, tiadinil or different
The report of metsulfovax compounding.
Summary of the invention
That the purpose of the present invention is to provide a kind of components is reasonable, bactericidal effect is good, drug cost is low, is not likely to produce drug resistance
Agricultural bactericidal composition.
To reach goal of the invention the technical solution adopted by the present invention is that:
A kind of bactericidal composition, containing two kinds of active components, the first active constituent is fluorobenzene ether amide, second of activity
Ingredient be selected from one of Isoprothiolane, tricyclazole, fenoxanil, Prochloraz, tiadinil and isotianil, two or three with
The mass ratio of upper combination, the first described active constituent and second active ingredient is 20:1~1:20.
As preferred mode, the mass ratio of the first described active constituent and second active ingredient be preferably 12:1~
1:12。
As further preferred mode, the mass ratio of the first described active constituent and second active ingredient is 6:1
~1:6.
As mode still further preferably, the mass ratio of the first described active constituent and second active ingredient is 3:
1~1:3.
Bactericidal composition of the present invention can be formulated into fungicide.When being formulated into fungicide, the sterilization
Agent contains above-mentioned bactericidal composition and carrier pesticide-acceptable, and the bactericidal composition accounts for the 1% of fungicide total weight
~80%.
As preferred mode, in the fungicide, bactericidal composition accounts for the 5%~80% of fungicide total weight.
Fungicide of the present invention can be configured to any dosage form agriculturally allowed, preferably water dispersible granules, suspension
Agent, wettable powder, aqueous emulsion or microemulsion.
For water dispersible granules, those skilled in the art, which are very familiar with, completes the present invention using corresponding auxiliary agent.Dispersion
Agent is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Wetting agent is selected from polyoxyethylene alcohol, alkyl sulfate, alkane
Base sulfonate, naphthalene sulfonate；Disintegrating agent is selected from ammonium sulfate, urea, sucrose, glucose, aluminium chloride, citric acid, succinic acid, carbonic acid
Hydrogen sodium；Binder is selected from diatomite, cornstarch, PVA, carboxymethyl (ethyl) cellulose family；Filler is selected from diatomite, kaolinite
Soil, white carbon black, light calcium, sepiolite, talcum powder, attapulgite, clay.
To wettable powder, workable auxiliary agent has: dispersing agent is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulphur
Hydrochlorate；Wetting agent is selected from alkyl sulfate, alkylsulfonate, naphthalene sulfonate；Filler is selected from ammonium sulfate, urea, sucrose, grape
Sugar, diatomite, kaolin, white carbon black, light calcium, talcum powder, attapulgite, clay.
To suspending agent, workable auxiliary agent has: dispersing agent be selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate,
TERSPERSE 2425 (Huntsman Corporation, the U.S. produces, alkyl naphthalene sulfonic acid salt)；Wetting agent is poly- selected from alkylphenol-polyethenoxy
Base ether formaldehyde condensation products sulfate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyoxyethylene groups ether phosphate, alkyl
Sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500 (Huntsman Corporation, U.S. product)；Thickener is selected from xanthan
Glue, polyvinyl alcohol, bentonite；Preservative is selected from formaldehyde, benzoic acid, sodium benzoate；Defoaming agent is organic silicon defoaming agent；It is antifreeze
Agent is selected from ethylene glycol, propylene glycol, glycerol, urea, inorganic salts such as sodium chloride.
To aqueous emulsion, workable auxiliary agent has: emulsifier is selected from Nonyl pheno (EO=10) ether phosphate, triphen
Ethyl -phenol polyoxyethylene ether phosphate (agriculture breast 600# phosphate), Nongru-700 #, agriculture breast 2201#, Span-60#, emulsifier T-
60, TX-10, agriculture breast 1601#, agriculture breast 600#, agriculture breast 400#；Solvent be selected from dimethylbenzene, toluene, cyclohexanone, solvent naphtha (trade mark:
S-150,S-180,S-200)；Stabilizer is selected from triphenyl phosphite, epoxychloropropane, aceticanhydride；Thickener is selected from xanthan gum, gathers
Vinyl alcohol, bentonite, aluminium-magnesium silicate；Preservative is selected from methanol, benzoic acid, sodium benzoate.
To microemulsion, workable auxiliary agent has: emulsifier is selected from calcium dodecyl benzene sulfonate (agriculture breast 500#), agriculture breast
700#, agriculture breast 2201#, this disk-60#, Tween-80-60#, TX-10, agriculture breast 1601, agriculture breast 600#, agriculture breast 400#；Assistant for emulsifying agent
Selected from methanol, isopropanol, n-butanol, ethyl alcohol；Solvent is selected from cyclohexanone, N-Methyl pyrrolidone, dimethylbenzene, toluene, solvent naphtha
(trade mark: S-150, S-180, S-200)；Stabilizer is selected from triphenyl phosphite, epoxychloropropane.
When fungicide of the present invention is water dispersible granules, as a preferred mode, the water dispersible granules
In each composition quality proportion are as follows: bactericidal composition 5~80%, dispersing agent 3~12%, wetting agent~-8%, disintegrating agent 1~
10%, binder 0~8%, filler complement to 100%.
When fungicide of the present invention is suspending agent, as a preferred mode, each ingredient in the suspending agent
Quality proportioning are as follows: bactericidal composition 1~80%, dispersing agent 2~6%, wetting agent 0.5~5%, thickener 0~2%, antifreezing agent 0
~5%, preservative 0~0.2%, defoaming agent 0~0.5%.
When fungicide of the present invention is wettable powder, as a preferred mode, the wettable powder
In each composition quality proportion are as follows: bactericidal composition 5~80%, dispersing agent 5~10%, wetting agent 0~10%, filler complement to
100%.
When fungicide of the present invention is aqueous emulsion, as a preferred mode, each ingredient in the aqueous emulsion
Quality proportioning are as follows: bactericidal composition 1~80%, emulsifier 3~10%, solvent 5~30%, stabilizer 0~1%, thickener 0~
1%, preservative 0~2%.
When fungicide of the present invention is microemulsion, as a preferred mode, each ingredient in the microemulsion
Quality proportioning are as follows: bactericidal composition 1~80%, assistant for emulsifying agent 5~10%, solvent 10~30%, is stablized emulsifier 15~25%
Agent 0~5%.
Composition of the invention can be provided in the form of finished product preparation, i.e., each substance has mixed in composition；Composition
Ingredient can also be provided with unit dose preparation, directly mixed in bucket (tank) using preceding.Concentrate of the invention is usually mixed with water
Close the concentration of active material required for obtaining.
Bactericidal composition or fungicide of the present invention are suitable for agricultural bactericidal.Particularly suitable on prevention and treatment rice
Important disease.The bactericidal composition or fungicide are particularly suitable for preventing and treating rice blast.
Bactericidal composition object provided by the invention can also be special with other compounds with weeding, desinsection or bactericidal property
It is not that protective fungicide is used in mixed way, it can also be mixed with nematicide, growth regulator, nutrient for plants or soil conditioner
It closes and uses.
The invention also includes a kind of methods of sterilization, before or after crop is susceptible, apply to crop and its growth place
With composition of the invention.Amount of application of the invention changes with weather condition or crop condition.The duration of protective effect is logical
It is often related with the content of single compound in composition, it is related to extraneous factor, such as weather, but by using dosage form appropriate
The influence of weather can be slowed down.
Bactericidal composition provided by the invention has the advantage that compared with prior art
(1) component is reasonable, has good preventive effect to rice blast, can reduce times for spraying, and drug cost is low, and described kills
The activity and the active simple superposition of bactericidal effect not instead of each component of bacteria composition, there is significant synergistic effect；
(2) bactericidal composition is made of the effective component of different role mechanism, and action site increases, and is conducive to overcome and be prolonged
The generation of slow germ drug resistance, and it is good to crop safety, meet the security requirement of pesticidal preparations.
Specific embodiment
Next combined with specific embodiments below invention is further explained, but does not limit the invention to these tools
Body embodiment.One skilled in the art would recognize that present invention encompasses may include in Claims scope
All alternatives, improvement project and equivalent scheme.
One, bioassay
Subjects: rice blast fungus (Pyricularia oryzae) is provided by Zhejiang University's biology.
Test method: using the bioactivity of potting rice seedling spray inoculation spore suspension method measurement medicament.Rice seedling is trained
Support stand-by to 1 heart stage of 2 leaf, reagent agent and comparison medicament are configured to the medical fluid of preset concentration, carry out spraying treatment, and every processing is set
4 repetitions.It takes the culture dish for covering with spore afterwards for 24 hours, is gently washed with sterile water and take surface Fresh spores, filtered with double gauze,
The suspension that spore concentration is 300,000/ml or so, spray inoculation pressure (0.1MPa) is made.Test material after inoculation moves to manually
In room (25 DEG C), 100% humidity dark culturing for 24 hours after, 85% humidity alternation of light and darkness culture is then moved to, to blank control after 7d
Sick grade investigation is carried out when sufficiently falling ill.Referring to " one GB/T 17980.19-2000 of field control effectiveness test criterion ", refer to calculating by disease
Preventive effect %.
1) grade scale:
0 grade: disease-free spot；
1 grade: leaf spot lesion number is less than 5, and length is less than 1 centimetre；
3 grades: leaf spot lesion number 6-10, part scab length is greater than 1 centimetre；
5 grades: leaf spot lesion number 11-25, part scab is linked to be piece, accounts for leaf area 10-25%；
7 grades: leaf spot lesion number 26 or more, scab is linked to be piece, accounts for leaf area 26-50%；
9 grades: scab is linked to be piece, accounts for 50% or more leaf area.
2) calculation method:
According to survey data, the disease index and control efficiency of each processing are calculated.
The calculating of co-toxicity coefficient.Each processing control efficiency is calculated with disease index, with " DPS data processing system " 3.11
Professional version carries out data analysis statistical, finds out regression straight line EC50, related coefficient.According to Sun Yunpei (Y-P Sun) method by each of measurement
The EC of processing50It is converted into practical poison exponent (ATI)；According to the mixture ratio, theoretical toxicity index (TTI) is obtained, by following
The co-toxicity coefficient (CTC) of formula calculating mixture.
Content (%) of the toxicity index × A of mixed toxicity index (the TTI)=A of theory in using with
Content (%) of the toxicity index × B of+B in using with
If co-toxicity coefficient is greater than 120, show there is synergistic effect；If being significantly lower than 100 (80 or less), it is shown to be antagonism work
With；Between 100~120, it is shown to be summation action.
Table 1: The Toxicity Determination result of the bactericidal composition to rice blast
Two, preparation is prepared
Percentage composition is mass percent in all formulations proportion.
1, water dispersible granules
By formula rate, the method by the frequent regulation water intaking dispersible granule such as raw medicine and dispersing agent, wetting agent, binder is
Mixing, ultra micro air-flow crushing, addition are equipped in the pelletizer of certain specification sieve and are granulated.Then it is through drying, screening again
Obtain granular product.
Example of formulations 1:60% fluorobenzene ether amide 'Daowenling ' water dispersible granule
Weigh 20% fluorobenzene ether amide, 40% Isoprothiolane, 3%TERSPERSE 2700,2% dispersing agent NNO (alkylnaphthalene sulphur
Hydrochlorate formaldehyde condensation products), 3% Nekal BX (nekal), 2%K-12 (lauryl sodium sulfate), 3% diatom
Soil, 5% glucose, kaolin add to 100%, obtain 60% fluorobenzene ether amide 'Daowenling ' water dispersible granule.
Example of formulations 2:40% fluorobenzene ether amide tricyclazole water dispersible granule
It weighs 20% fluorobenzene ether amide, 20% tricyclazole, 3%TERSPERSE 2700,3% dispersing agent NNO, 2% pull open
Powder BX, 1%K-12,1% carboxymethyl cellulose, 3% urea, diatomite add to 100% mass parts, obtain 40% fluorobenzene ether acyl
Amine tricyclazole water dispersible granule.
Example of formulations 3:78% fluorobenzene ether amide fenoxanil water dispersible granules
Weigh 40% fluorobenzene ether amide, 38% fenoxanil, 4%TERSPERSE 2700,2% dispersing agent NNO, 2% drawing
It opens powder BX, 1%K-12,3% cornstarch, 3% sulphur ammonium, attapulgite and adds to 100% mass parts, obtain 78% fluorobenzene ether acyl
Amine fenoxanil water dispersible granules.
Example of formulations 4:70% fluorobenzene ether amide tiadinil water dispersible granules
Weigh 40% fluorobenzene ether amide, 30% tiadinil, 4%TERSPERSE 2700,2% dispersing agent NNO, 2% drawing
It opens powder BX, 1%K-12,3% cornstarch, 3% sulphur ammonium, attapulgite and adds to 100% mass parts, obtain 70% fluorobenzene ether acyl
Amine tiadinil water dispersible granules.
Example of formulations 5:80% fluorobenzene ether amide isotianil water dispersible granules
Weigh 40% fluorobenzene ether amide, 40% isotianil, 4%TERSPERSE 2700,2% dispersing agent NNO, 2% drawing
It opens powder BX, 1%K-12,3% cornstarch, 3% sulphur ammonium, attapulgite and adds to 100% mass parts, obtain 80% fluorobenzene ether acyl
Amine isotianil water dispersible granules.
Example of formulations 6:60% fluorobenzene ether amide Prochloraz water dispersible granules
Weigh 30% fluorobenzene ether amide, 30% Prochloraz, 3%TERSPERSE 2700,2% dispersing agent NNO (alkylnaphthalene sulphur
Hydrochlorate formaldehyde condensation products), 3% Nekal BX (nekal), 2%K-12 (lauryl sodium sulfate), 3% diatom
Soil, 5% glucose, kaolin add to 100%, obtain 60% fluorobenzene ether amide Prochloraz water dispersible granules.
2, suspending agent
By formula rate, using water as medium, raw medicine, dispersing agent, suspending agent and antifreezing agent etc. is added in batching kettle and mixed
It closes uniformly, disperses 30min through ball mill or high speed shear, suspending agent is made after being sanded with sand mill.
Example of formulations 7:40% fluorobenzene ether amide tricyclazole suspending agent
Weigh 15% fluorobenzene ether amide, 25% tricyclazole, 2%TERSPERSE 2500,3%TERSPERSE 2425,
0.2% xanthan gum, 3% white carbon black, 5% ethylene glycol, 0.3% benzoic acid, 0.5% organic silicon defoamer (trade name: the Nanjing s-29
"four news" (new ideas applied chemistry product company produces), deionized water adds to 100% mass parts, and it is outstanding to obtain 40% fluorobenzene ether amide tricyclazole
Floating agent.
Example of formulations 8:40% fluorobenzene ether amide Isoprothiolane suspending agent
Weigh 15% fluorobenzene ether amide, 25% Isoprothiolane, 2500,0.1% xanthan gum of 2%NNO, 2%TERSPERSE,
3% white carbon black, 5% propylene glycol, 0.5% formaldehyde, 0.5% organic silicon defoamer, deionized water add to 100% mass parts, obtain
40% fluorobenzene ether amide Isoprothiolane suspending agent.
Example of formulations 9:25% fluorobenzene ether amide Prochloraz suspending agent
Weigh 15% fluorobenzene ether amide, 10% Prochloraz, 1%TERSPERSE 2500,1%TERSPERSE 2425,
0.2% xanthan gum, 3% white carbon black, 5% ethylene glycol, 0.3% benzoic acid, 0.5% organic silicon defoamer, deionized water add to
100% mass parts obtain 25% fluorobenzene ether amide Prochloraz suspending agent.
Example of formulations 10:60% fluorobenzene ether amide fenoxanil suspending agent
Weigh 30% fluorobenzene ether amide, 30% fenoxanil, 1%TERSPERSE 2500,1%TERSPERSE 2425,
0.2% xanthan gum, 3% white carbon black, 5% ethylene glycol, 0.3% benzoic acid, 0.5% organic silicon defoamer, deionized water add to
100% mass parts obtain 60% fluorobenzene ether amide fenoxanil suspending agent.
Example of formulations 11:25% fluorobenzene ether amide tiadinil suspending agent
Weigh 12.5% fluorobenzene ether amide, 12.5% tiadinil, 1%TERSPERSE 2500,1%TERSPERSE
2425,0.2% xanthan gum, 3% white carbon black, 5% ethylene glycol, 0.3% benzoic acid, 0.5% organic silicon defoamer, deionized water add
To 100% mass parts, 25% fluorobenzene ether amide tiadinil suspending agent is obtained.
Example of formulations 12:15% fluorobenzene ether amide isotianil suspending agent
Weigh 10% fluorobenzene ether amide, 5% isotianil, 10% polycarboxylate, 3% lauryl sulfate, 1% xanthan
Glue, 5% sodium chloride, deionized water add to 100% mass parts, obtain 15% fluorobenzene ether amide isotianil suspending agent.
3, wettable powder
By recipe requirements, after mixing after Roughpulverizer crushes, sufficiently it is pulverized and mixed into airslide disintegrating mill and is made wettable
Property pulvis.
Example of formulations 13:80% fluorobenzene ether amide Isoprothiolane wettable powder
Weigh 30% fluorobenzene ether amide, 50% Isoprothiolane, 5% calcium lignosulfonate, 2% Nekal BX, 1%K-12,5%
White carbon black, kaolin add to 100% mass parts, obtain 80% fluorobenzene ether amide Isoprothiolane wettable powder.
Example of formulations 14:65% fluorobenzene ether amide tricyclazole wettable powder
60% fluorobenzene ether amide, 5% tricyclazole, 4% calcium lignosulfonate, 3%TERSPERSE 2700,2% is weighed to draw
It opens powder BX, 2%K-12,5% white carbon black, light calcium and adds to 100% mass parts, obtain 65% fluorobenzene ether amide tricyclazole wettable
Pulvis.
Example of formulations 15:52% fluorobenzene ether amide fenoxanil wettable powder
Weigh 4% fluorobenzene ether amide, 48% fenoxanil, 4% calcium lignosulfonate, 4% dispersing agent NNO, 2% pull open powder
BX, 2%K-12,5% white carbon black, attapulgite add to 100% mass parts, and it is wettable to obtain 52% fluorobenzene ether amide fenoxanil
Property pulvis.
Example of formulations 16:60% fluorobenzene ether amide Prochloraz wettable powder
50% fluorobenzene ether amide, 10% Prochloraz, 4% calcium lignosulfonate, 3%TERSPERSE 2700,2% is weighed to draw
It opens powder BX, 2%K-12,5% white carbon black, light calcium and adds to 100% mass parts, obtain 60% fluorobenzene ether amide Prochloraz wettable
Pulvis.
Example of formulations 17:65% fluorobenzene ether amide tiadinil wettable powder
Weigh 60% fluorobenzene ether amide, 5% tiadinil, 4% calcium lignosulfonate, 3%TERSPERSE 2700,2%
Nekal BX, 2%K-12,5% white carbon black, light calcium add to 100% mass parts, and obtaining 65% fluorobenzene ether amide tiadinil can
Wet powder.
Example of formulations 18:80% fluorobenzene ether amide isotianil wettable powder
Weigh 55% fluorobenzene ether amide, 25% isotianil, 3% calcium lignosulfonate, 2% lauryl sodium sulfate,
10% white carbon black, kaolin add to 100% mass parts, obtain 80% fluorobenzene ether amide isotianil wettable powder.
4, microemulsion
Example of formulations 19:15% fluorobenzene ether amide tricyclazole microemulsion
Weigh 5% fluorobenzene ether amide, 10% tricyclazole, 4%TX-10,5% Nongru-700 #, 6% agriculture breast 500#, 4% agriculture breast
1601#, it 15% cyclohexanone, 5%N- methyl pyrrolidone, 5% n-butanol, 1% epoxychloropropane, is dissolved completely and is mixed equal
Even, deionized water adds to 100% mass parts, and 15% fluorobenzene ether amide tricyclazole microemulsion is made after stirring.
Example of formulations 20:20% fluorobenzene ether amide Isoprothiolane microemulsion
Weigh 10% fluorobenzene ether amide, 10% Prochloraz, 5% agriculture breast 400#, 4% agriculture breast 500#, 6% agriculture breast 1601#,
25% cyclohexanone, 5% isopropanol, 3% triphenyl phosphite, is dissolved completely and is uniformly mixed, deionized water 5% dimethylbenzene
100% mass parts are added to, 20% fluorobenzene ether amide Isoprothiolane microemulsion is made after stirring.
5, aqueous emulsion
Example of formulations 21:15% fluorobenzene ether amide prochloraz aqueous emulsion
Weigh 10% fluorobenzene ether amide, 5% Prochloraz, 3% agriculture breast 2201#, 1.5% Nonyl pheno (EO=10)
Ether phosphate, 2.5% triphenoethyl benzene phenol polyethenoxy ether phosphate (agriculture breast 600# acid phosphatide), 2%Span-60#, 1% ring
Oxygen chloropropane, 20% dimethylbenzene, 10% cyclohexanone, 0.3% xanthan gum, 0.5% benzoic acid, deionized water add to 100% mass
Part.For above-mentioned raw materials through mixing, 15% fluorobenzene ether amide prochloraz aqueous emulsion is made in high speed shearing emulsification.
Example of formulations 22:10% fluorobenzene ether amide tiadinil aqueous emulsion
Weigh 5% fluorobenzene ether amide, 5% tiadinil, 3% agriculture breast 2201#, 1.5% Nonyl pheno (EO=
10) ether phosphate, 2.5% triphenoethyl benzene phenol polyethenoxy ether phosphate (agriculture breast 600# acid phosphatide), 2%Span-60#, 1%
Epoxychloropropane, 20% dimethylbenzene, 10% cyclohexanone, 0.3% xanthan gum, 0.5% benzoic acid, deionized water add to 100% matter
Measure part.For above-mentioned raw materials through mixing, 10% fluorobenzene ether amide tiadinil aqueous emulsion is made in high speed shearing emulsification.
Example of formulations 23:5% fluorobenzene ether amide isotianil aqueous emulsion
Weigh 1% fluorobenzene ether amide, 4% isotianil, 2% agriculture breast 2201#, 3.5% triphenoethyl benzene phenol polyethenoxy
Ether phosphate, 3%Span-60#, 1% epoxychloropropane, 30% dimethylbenzene, 0.3% xanthan gum, 0.5% benzoic acid, deionization
Water adds to 100% mass parts.For above-mentioned raw materials through mixing, 5% fluorobenzene ether amide isotianil water and milk is made in high speed shearing emulsification
Agent.
Three, Field information
Rice blast field control effectiveness test is prevented and treated referring to medicine inspecting institute, the Ministry of Agriculture " GB-T 17980.19-2000 pesticide field
The regulation of pharmacodynamic test criterion (one) --- bactericidal agent for preventing and treating rice leaf diseases ", test medicine, comparison medicament and blank control
Cell processing using random district's groups arrange, plot area 25m2, 4 repetitions, the total application of this test application for the first time twice
When rice be in the rice cut phase, second rice when being administered is in full heading time, and rice blast is mainly panicle blast, in morbidity
Initial stage.The total investigation of this test 2 times, every experimental plot investigates 250 using 5 points of parallel great-jump-forward samplings, every 50 fringes of investigation altogether
Fringe investigates every clump of every fringe incidence, records disease grade.
1) disease scale standard is as follows:
0 grade: disease-free；
1 grade: every 5% or less fringe loss (individual branch stalk morbidities)；
3 grades: every fringe loss 6%~20% (morbidity of one third or so branch stalk)；
5 grades: every fringe loss 21%~50% (fringe neck or main shaft morbidity, grain half are flat)；
7 grades: every fringe loss 51%~70% (fringe neck morbidity, big portion half are flat)；
9 grades: every fringe loss 71%~100% (fringe neck morbidity, cause dead ears).
2) drug effect calculation method
According to investigation result, disease index and preventive effect are calculated according to following (1), (2) formula.Test data uses Deng Kenshi
Duncan's new multiple range method (DMRT) is for statistical analysis.
In formula: CK0, CK1 are respectively that blank district is administered forward and backward disease index；PT0, PT1 are respectively chemicals treatment
The forward and backward disease index of area's medicine.
Table 2: prevention and treatment rice blast field test results
From above embodiments data it is found that bactericidal composition provided by the invention cannot have special efficacy, Er Qiesuo to rice blast
Bactericidal composition is stated compared to single dose, is had significant synergies.Meanwhile bactericidal composition provided by the invention is to trial crops
Without obvious harmful effects, leaf color, growing way etc. are all normal, and safety is good, meets the security requirement of pesticidal preparations.
Claims (10)
1. a kind of bactericidal composition, it is characterised in that the bactericidal composition contains two kinds of active components, the first active constituent
For fluorobenzene ether amide, second active ingredient is selected from Isoprothiolane, tricyclazole, fenoxanil, Prochloraz, tiadinil and different thiophene bacterium
The mass ratio of one of amine, two or three of combination of the above, the first described active constituent and second active ingredient is 20:
1~1:20.
2. bactericidal composition described in accordance with the claim 1, it is characterised in that the first described active constituent and second of activity
The mass ratio of ingredient is 12:1~1:12.
3. bactericidal composition according to claim 2, it is characterised in that the first described active constituent and second of activity
The mass ratio of ingredient is 6:1~1:6.
4. bactericidal composition described in accordance with the claim 3, it is characterised in that the first described active constituent and second of activity
The mass ratio of ingredient is 3:1~1:3.
5. bactericidal composition described in accordance with the claim 1, it is characterised in that the bactericidal composition is formulated into fungicide, institute
It states fungicide and contains bactericidal composition and carrier pesticide-acceptable, the bactericidal composition accounts for the 1% of fungicide total weight
~80%.
6. bactericidal composition according to claim 5, it is characterised in that the bactericidal composition accounts for fungicide total weight
5%~80%.
7. bactericidal composition according to claim 5, it is characterised in that the fungicide is formulated into water dispersible granules, hangs
Floating agent, wettable powder, aqueous emulsion or microemulsion.
8. according to bactericidal composition described in one of claim 1 to 7, it is characterised in that the bactericidal composition is used for agricultural
Sterilization.
9. bactericidal composition according to claim 8, it is characterised in that the bactericidal composition be used to prevent and treat rice blast.
10. bactericidal composition according to claim 7, it is characterised in that:
Each composition quality proportion in the water dispersible granules are as follows: bactericidal composition 5~80%, dispersing agent 3~12%, wetting agent
~-8%, disintegrating agent 1~10%, binder 0~8%, filler complement to 100%；
Each composition quality proportion in the suspending agent are as follows: bactericidal composition 1~80%, dispersing agent 2~6%, wetting agent 0.5~
5%, thickener 0~2%, antifreezing agent 0~5%, preservative 0~0.2%, defoaming agent 0~0.5%；
Each composition quality proportion in the wettable powder are as follows: bactericidal composition 5~80%, dispersing agent 5~10%, wetting agent 0
~10%, filler complements to 100%；
Each composition quality proportion in the aqueous emulsion are as follows: bactericidal composition 1~80%, emulsifier 3~10%, solvent 5~30%,
Stabilizer 0~1%, thickener 0~1%, preservative 0~2%；
Each composition quality proportion in the microemulsion are as follows: bactericidal composition 1~80%, emulsifier 15~25%, assistant for emulsifying agent 5~
10%, solvent 10~30%, stabilizer 0~5%.
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| CN201710780512.8A CN109418270A (en) | 2017-09-01 | 2017-09-01 | A kind of bactericidal composition of fluorine-containing phenylate amide |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710780512.8A CN109418270A (en) | 2017-09-01 | 2017-09-01 | A kind of bactericidal composition of fluorine-containing phenylate amide |
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