CN108419798A - A kind of bactericidal composition and its application containing alkene oxime amine - Google Patents
A kind of bactericidal composition and its application containing alkene oxime amine Download PDFInfo
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- CN108419798A CN108419798A CN201710075714.2A CN201710075714A CN108419798A CN 108419798 A CN108419798 A CN 108419798A CN 201710075714 A CN201710075714 A CN 201710075714A CN 108419798 A CN108419798 A CN 108419798A
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- alkene oxime
- agent
- disease
- anthracnose
- blight
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention belongs to pesticide fields, and in particular to a kind of composition pesticide and its application.The composition is made of active constituent, filler and auxiliary agent.Wherein active components A is alkene oxime amine, and active constituent B is one or more in benzoxazole, imazalil, cyazofamid, metconazole.The composition by sac fungus, basidiomycetes, Fungi Imperfecti and the fungus-caused plurality of plant diseases of Oomycete class to having good control effect, cucumber downy mildew, powdery mildew, anthracnose, scab can effectively be prevented, tomato late blight, leaf mold, early blight, gray mold, the generation and harm of the plant diseases such as western melon powdery mildew, anthracnose, blight dis-ease, droop.The composition wide sterilization spectrum has apparent synergistic effect, can reduce dosage, reduces drug cost, and germ is delayed to generate and develop the resistance of single medicine, thus can effectively delay the occurrence and development of pathogen drug resistance.
Description
Technical field
The invention belongs to pesticide fields.Be related to a kind of bactericidal composition and its application, and in particular to one kind containing it is active at
The composition of point A alkene oxime amines and active constituent B (one or more in benzoxazole, imazalil, cyazofamid, metconazole) and its
Using.
Background technology
Crop-planting is given every year by sac fungus, basidiomycetes, Fungi Imperfecti and the fungus-caused plurality of plant diseases of Oomycete class
Different degrees of loss is caused with production.Sac fungus, basidiomycetes, oomycetes and the fungus-caused plant disease of Fungi Imperfecti include Huang
Melon downy mildew, powdery mildew, anthracnose, scab, tomato late blight, leaf mold, early blight, gray mold, western melon powdery mildew, charcoal
Subcutaneous ulcer disease, blight dis-ease, droop, downy mildew of garpe, anthracnose, powdery mildew, anthrachose of grape, white rot, gray mold, apple spot fallen leaves
Disease, brown spot, scab, ring spot, anthracnose, melon and pepper anthracnose, epidemic disease, flowers powdery mildew and leaf spot, wheat
Head blight, powdery mildew and rust, rice sheath blight disease, bakanae disease, maize sheath blight, head smut, the late blight of potato, early blight
Deng.
It is the most effective means of controlling plant diseases using chemical agent.Methoxy acrylic bactericide and azoles
Series bactericidal agent is the mainstream fungicide of controlling plant diseases, but applies single chemical bactericide to continuous high dose for a long time, is held
The problems such as easily causing residual, environmental pollution and the pathogen drug resistance of medicament.
Rational chemical bactericide combination or mixture, which has, expands fungicidal spectrum, improves control effect, extends the optimum period for applying fertilizer, subtracts
Few dosage reduces poisoning, reduces residual, delaying the effects that generation and development of pathogen drug resistance, and bactericide compounded is solution
Certainly one of the maximally efficient method of the above problem.Develop new product fungicide price is constantly soaring, and in contrast, it studies and opens
Hair efficiently, the compounding of low toxicity, low-residual have that small investment, the lead time is short and is paid attention to both at home and abroad, it is numerous and confused increase to develop grinds
Dynamics processed.We based on the indoor screening and field trials, specify alkene oxime amine and benzoxazole, imazalil, cyazofamid or
Metconazole is compounded, and has apparent synergistic effect.
And so far, there are no documents to disclose alkene oxime amine and benzoxazole, imazalil, cyazofamid or metconazole sterilization group
Object is closed, and by the composition of gained for preventing agricultural disease.
Invention summary
Present invention aims at by alkene oxime amine and benzoxazole, imazalil, cyazofamid or metconazole rational mixture, obtain
Bactericidal composition, for preventing agricultural disease.The composition can improve control effect, delay pathogen development of drug resistance, subtract
Few peasant's drug cost.
The present composition also with that can improve crop growth, development, makes crop generate positive physiological effect
Effect, including improve crop quality, improve yield and crop commodity rate etc..
The present composition has following remarkable result and advantage：Active components A is alkene oxime amine, and active constituent B is selected from nitrile
One or more in benzene azoles, imazalil, cyazofamid, metconazole, active constituent B preferably is selected from one kind in metconazole, benzoxazole
Or it is a variety of.Active components A is mitochondrial respiratory inhibitor, inhibits the electron transmission of mitochondria, active constituent B that can then inhibit disease
The biosynthesis of bacterium cell important component, so as to cause germ cell death.Active components A and active constituent B both tool
There is different mechanism of action, cross resistance is not present, can be synergistic, it reduces and single dose is used alone.
It is killed made of being compounded with benzoxazole, imazalil, cyazofamid or metconazole by alkene oxime amine the present invention provides one kind
Bacteria composition.The present invention also provides the formula indoor screening test experiment of different component formula, field control effectiveness tests.
According to the one side of the application, this application provides a kind of composition pesticide, the composition pesticide contains two
Kind active component：Active components A is alkene oxime amine, and active constituent B is in benzoxazole, imazalil, cyazofamid or metconazole
It is one or more.
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:80~
80:1。
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:60~
60:1。
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:20~
20:1。
According to the certain embodiments of the application, it is total that the weight summation of the active component of the composition pesticide accounts for composition
The 5%~81% of weight.
According to the certain embodiments of the application, it is total that the weight summation of the active component of the composition pesticide accounts for composition
The 10~61% of weight.
(solid or liquid well known to those skilled in the art may be used in the preparation of the composition finished product preparation of the present invention
Body) carrier and various auxiliary agents.
According to the certain embodiments of the application, the composition pesticide can be prepared into suitable agriculture by common processing method
A kind of dosage form that industry uses.After active component is mixed with liquid-carrier (solvent) or solid carrier, it is added one or more of
Surfactant such as emulsifier, dispersant, wetting agent, adhesive, stabilizer and antifoaming agent etc..Containing at least in usual composition
A kind of carrier and at least one surfactant.In all cases, it should be ensured that present composition active component is uniformly distributed.
According to the certain embodiments of the application, the present composition can be prepared into suitable agricultural use by known method
A kind of dosage form, relatively good dosage form has aqueous suspension agent, dispersible oil-suspending agent, aqueous emulsion, microemulsion, wettable powder, outstanding
Floating seed coat agent, water dispersible granules, seed treatment dispersible pulvis, seed treatment microcapsule suspending agent or missible oil etc..
According to the certain embodiments of the application, the composition pesticide is at foliar spray, seed treatment or soil
Reason.
According to the property of these compositions and application composition institute's purpose to be achieved and ambient conditions, can select by
Composition to spray, impregnate, atomizing, broadcast sowing, pour, the application of the method for pouring root or the like.
According to the one side of the application, this application provides the use that the composition pesticide is used for controlling plant diseases
On the way.
According to the certain embodiments of the application, the plant disease is by sac fungus, basidiomycetes, oomycetes and Fungi Imperfecti
Fungi causes.
According to the certain embodiments of the application, the plant disease is cucumber downy mildew, powdery mildew, anthracnose, black star
Disease, tomato late blight, leaf mold, early blight, gray mold, western melon powdery mildew, blight dis-ease, droop, downy mildew of garpe, anthrax
Disease, powdery mildew, anthrachose of grape, white rot, gray mold, alternaria leaf spot of apple, scab, ring spot, anthracnose, melon and capsicum
Anthracnose, epidemic disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice sheath blight disease, bakanae disease, corn
Banded sclerotial blight, head smut, the late blight of potato, early blight etc..
According to the one side of the application, this application provides a kind of method of controlling plant diseases, the method is by institute
It states composition and is applied to Cereal, fruit tree, vegetables and industrial crops or its planting area, with controlling plant diseases.
According to the certain embodiments of the application, the plant disease is by sac fungus, basidiomycetes, oomycetes and Fungi Imperfecti
Fungi causes.
According to the certain embodiments of the application, the plant disease is cucumber downy mildew, powdery mildew, anthracnose, black star
Disease, tomato late blight, leaf mold, early blight, gray mold, western melon powdery mildew, anthracnose, blight dis-ease, droop, grape downy mildew
Disease, anthracnose, powdery mildew, anthrachose of grape, white rot, gray mold, alternaria leaf spot of apple, brown spot, scab, ring spot, charcoal
Subcutaneous ulcer disease, melon and pepper anthracnose, epidemic disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice line
Blight, bakanae disease, maize sheath blight, head smut, the late blight of potato, early blight etc..
According to the certain embodiments of the application, the component of the composition pesticide is configured to preparation application or bucket is mixed and applied
With.
According to the one side of the application, this application provides a kind of method preparing the composition pesticide, the sides
Method is by the active components A, active constituent B and agriculturally acceptable carrier or auxiliary agent mix.
Detailed description of the invention
Definition
Alkene oxime amine (Fenaminstrobin) chemical name：N- methyl -2- [2- ((((1- methyl -3- (2,6- dichloro-benzenes
Base) -2- acrylic) amino) oxygroup) methyl) phenyl] -2- methoxyimino acetic amides, CAS registration numbers：366815-39-6.
Have the following structure formula：
Alkene oxime amine wide sterilization spectrum, activity are high, have prevention and therapeutic effect and have with environmental organism good compatible
Property.It is good to being had by the fungus-caused plurality of plant diseases such as mastigomycetes, zygomycete, sac fungus, basidiomycetes and Fungi Imperfecti
Preventive effect.Preferable preventive and therapeutic effect can be all had to multiple diseases, especially to white powder on the crops such as cereal, fruit tree, vegetables
Disease, rust, leaf spot preventive effect are notable.
Benzoxazole (Fenbuconazole) chemical name：4- (4- chlorphenyls) -2- phenyl -2 (1H-1,2,4- triazoles -1-
Ylmethyl) butyronitrile, CAS registration numbers:114369-43-6.Have the following structure formula：
Benzoxazole is called azoles bacterium nitrile, benzene cyanogen azoles, is triazole type systemic fungicide, and sterol demethylation inhibitors can prevent
The germ spore intrusion crop plant tissue to have germinateed, inhibits the growth of mycelia.It is used in germ incubation period, the hair of germ can be prevented
It educates；It is used after the onset, next-generation spore can be made to deform, lose infection ability, there is prevention effect and therapeutic effect to disease.
To the Septoria of cereal crop, Puccinia and rye beak spore, the beet on beet gives birth to tail spore, the Botrytis cinerea on grape
Belong to, grape Guignardia and grape snag shell, the Monilia on drupe, such as venturia inaequalis and to crop field work on fruit tree
Object, rice, banana, vegetables and many diseases of garden crop are effective.
Imazalil (Imazalil) chemical name：(±) allyl 1- (2,4- dichlorophenyl) -2- imidazoles -1- base ethyls
Ether, CAS registration numbers:35554-44-0.Have the following structure formula：
Imazalil is called enzyme, for preventing the crop diseases such as citrus, mango, banana, apple, melon, it can also be used to
Cereal crops disease is prevented, has special efficacy to the penicillium of resisting carbendazim, probenazole.Also have to fruits and vegetables powdery mildew, anthracnose good
Good preventive effect.
Cyazofamid (Cyazofamid) chemical name：Chloro- 2- cyano-N, N- dimethyl -5- the p-methylphenyl imidazoles -1- sulphurs of 4-
Amide, CAS registration numbers:120116-88-3.Have the following structure formula：
Cyazofamid is sulfanilamide (SN) imidazoles protective fungicide, is had to downy mildew, epidemic disease, late blight, clubroot, samping off etc.
Special efficacy.Mechanism of action is that the electron transmission of mitochondrial cytochrome b c1 complexs in Oomycete germ body is blocked to carry out interfering energy
Supply, binding site is the centers Q of enzyme, referred to as QiI (inhibitor, Quinone inside inside benzoquinones
Inhibitors) series bactericidal agent, with other fungicide without cross tolerance.It may be due to target to the high selection activity of pathogen
Enzyme is marked caused by the sensitivity difference of medicament.To Oomycete fungal such as downy mildew, Pseudo peronospara, phytophthora, pythium spp with
And the plasmodiophora brassica bacteria of Plasmodiophoromycetes has very high bioactivity.
Metconazole (Metconazole) chemical name：5- (4- chlorphenyls) -2,2- dimethyl -1- (1H-1,2,4- triazoles -
1- ylmethyls) cyclopentanol, molecular formula C17H22ClN3O, CAS registration number：125116-23-6.Structural formula is as follows：
Metconazole by Japanese Wu Yu chemical industrial companies and american cyanamide (being now BASF) joint development, to wheat, corn,
Many diseases that leaf, the fringe of rapeseed, soybean, lawn, fruit tree etc. occur have very high preventive effect, are mainly used for cereal crops
Prevent disease caused by head blight, short shape rust, leaf rust, yellow rust, crown rust, powdery mildew, glume blight and septoria musiva etc..
For C-14 demethylation enzyme inhibitors in ergosterol biosynthesis.Although the mechanism of action as other triazole bactericidal agents,
But then difference is larger for activity profile.Two kinds of isomers have bactericidal activity, but Cis activity is higher than trans-.The antifungal spectrum of metconazole
Widely, and activity is splendid.Metconazole field is applied has remarkable effect to cereal crops septoria musiva, fusarium and handle rest fungus plant disease
Fruit.For metconazole compared with traditional biocide agent, dosage is extremely low and prevents cereal and plants sick range very extensively.
Term " composition pesticide " indicate one or more active constituents containing antimicrobial effective amount or its agriculturally
Acceptable tautomer, solvate, hydrate or salt, with other auxiliary agents, the mixture of carrier.By the active constituent
The purpose for being prepared into bactericidal composition is in order to more easily to agricultural irrigation dispenser.In the application, " composition pesticide " is also referred to as
For " bactericidal composition ".
Term " active constituent ", also known as " active ingredient ", " active component " refer to and play sterilization work in the bactericidal composition
Key active ingredients or its agriculturally acceptable tautomer, solvate, hydrate or salt.In certain of the application
In a little embodiments, the active constituent of the bactericidal composition includes A alkene oxime amines.In the certain embodiments of the application,
The active constituent B (one kind in benzoxazole, imazalil, cyazofamid and metconazole) of the bactericidal composition.In the application
Certain embodiments in, the active constituent of the bactericidal composition includes A and B.In the certain embodiments of the application, institute
The active constituent for stating bactericidal composition is made of A and B.
Term " auxiliary agent ", also known as " adjuvant " are Pesticide formulations or in use, are used to improve medicament physicochemical property
Auxiliary substance.Including wetting agent, emulsifier, solvent, dispersant, sticker, stabilizer, synergist, safener, bleeding agent
Deng.Such as in agriculture breast 1601#, alkylaryl sulfonates, lignosulfonates, lactic casein, mineral oil, gelatin, polyvinyl alcohol etc.
It is one or more.
Term " carrier " refer to can it is combined with active constituent or combine with make it easier for being administered to object (such as plant,
Crop or careless class) natural or synthetic organic or inorganic compound.Therefore, the carrier is preferably inert, at least should be
Agricultural is acceptable.The carrier can be solid or liquid.
The carrier that can be used in the present invention can be used as solid carrier either solid can also be liquid
Have for example：Phyteral powdery type (such as soy meal, starch, grain dust, wood powder, bark powder, sawdust, walnut shell powder, wheat bran,
The particle of cellulose powder, coconut husk, corncob and tobacco stem extracts the residue etc. after plant essence), paper, sawdust, crush
The synthesized polymer body of synthetic resin etc., clay class (such as kaolin, bentonite, acid china clay, attapulgite etc.), talcum powder class.
Silica (such as diatomite, silica sand, mica, aqueous silicic acid, calcium silicates), activated carbon, natural mineral matter class (float stone, green slope thread
Stone and zeolite etc.), fire diatomite, sand, (such as polyethylene, polypropylene, polyvinylidene chloride etc.), the chlorination such as plastics medium
Chemical fertilizer, the soil of the inorganic mineral powder of potassium, calcium carbonate, calcium phosphate etc., ammonium sulfate, ammonium phosphate, urea, ammonium chloride etc.
Fertilizer and white carbon, zeolite powder, the wooden chaff, paraffin, methylcellulose, carboxymethyl cellulose and carboxyethyl cellulose etc., these objects
Matter can be used alone or two or more is mixed.
What can be used as liquid-carrier can select in llowing group of materials, such as water, alcohols (such as methanol, ethyl alcohol,
Isopropanol, butanol, ethylene glycol etc.), ketone (such as acetone, methyl ethyl ketone, isobutyrone, cyclohexanone etc.), ethers (example
Such as ether, dioxanes, methylcellulose, tetrahydrofuran), aliphatic hydrocarbon class (such as kerosene, mineral oil etc.), virtue
Fragrant race's hydrocarbon (such as benzene,toluene,xylene, solvent naphtha, alkylnaphthalene, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbon, chlorobenzene,
Deng), halogenated hydrocarbon class, amides, sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, animal oil, agriculture breast 1601#, alkane
Base arylsulphonate, lignosulfonates, lactic casein, gelatin, polyvinyl alcohol etc..
As other adjuvants can according to use purpose select to use, also can be used alone, certain occasions two or more
Adjuvant shares or certain occasions can not use adjuvant completely.For make active ingredient compound emulsification, dispersion, it is solubilized,
And/or wetting can use surfactant that can for example enumerate fatty alcohol polyoxyethylene ether, polyxyethylated aryl
Ether, polyoxyethylene higher fatty acid esters, polyoxyethylene alcohol or the phosphate of phenol, the aliphatic ester of polyalcohol, alkane aromatic sulfonic acid, naphthalene sulphur
Branch dress copolymer, butyl naphthalene sulfonate, alkylaryl sulfonates, the alkyl of acid polymer, lignosulfonates, macromolecule comb shape
The polyacrylates such as sodium sulfosuccinate, grease, fatty alcohol and ethylene oxide condensate, alkyltaurate, protein hydrolysis
Object.Suitable oligosaccharide object or polymer, for example, based on individual vinyl monomer, acrylic acid, EO and/or PO or its with for example
The combination of (polynary) alcohol or (polynary) amine.
To make active ingredient dispersion stability, attachment and/or combination, such as xanthans, aluminium-magnesium silicate, bright can be used
Glue, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid (such as cephalin and lecithin) and synthesis
The adjuvants such as phosphatide, bentonite, sodium lignin sulfonate.
The wherein optional spent glycol of antifreezing agent, propylene glycol, glycerine, sorbierite.Deflocculant as suspension product
The adjuvant such as naphthalene sulfonic acid polymer, polymeric phosphate can be used.
Organic silicon defoamer can be used in antifoaming agent.
Optionally, also may include other annexing ingredients, for example, protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent,
Stabilizer, screening agent.
Herein described bactericidal composition contains active components A and active constituent B, has apparent synergistic effect.This Shen
Please term " synergistic effect " used, also known as " act synergistically ", referring to different chemical substances has when being used in combination and cooperate
Effect, the effect with obvious effects higher than each separate constituent of generation.
According to the certain embodiments of the application, the control effect of the bactericidal composition is than any one separate constituent
Control effect is higher by 10% or more, for example, be higher by 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%,
19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%,
34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%,
49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%,
64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%,
79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%,
94%, 95%, 96%, 97%, 98%, 99% or more or it is higher by 100%.
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:80~
80:1, such as 1:80~75:1、1:80~60:1、1:80~40:1、1:80~10:1、1:60~5:1、1:40~3:1、1:20
~2:1、1:20~20:1、1:20~40:1、1:20~60:1；Preferably 1:60~60:1, such as 1:55~55:1、1:40~
40:1、1:30~30:1、1:20~20:1、1:10~10:1、1:5~5:1；More excellent is 1:20~20:1, such as 1:18~18:
1、1:15~15:1、1:10~10:1、1:5~5:1、1:5~1:1、1:4~1:1、1:3~1:1、1:2~1:1、4:1~15:
1.According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 80:1、60:1、
40:1、20:1、10:1、5:1、3:1、1:1、1:3、1:5、1:10、1:20、1:40、1:60、1:80。
According to the certain embodiments of the application, in one embodiment, the active component of the composition pesticide
Weight summation accounts for the 5%~81% of composition gross weight, for example, 5%~70%, 5%~60%, 5%~50%, 5%~40%,
5%~30%, 5%~20%, 5%~10%, 10%~81%, 10%~70%, 20%~81%, 20%~70%,
30%~81%, 30%~70%, 40%~81%, 40%~70%, 50%~81%, 50%~70% or 60%~
81%；Preferably 10~61%, such as 10~50%, 10~40%, 10~30%, 10~20%, 20~61%, 20~
50%, 20~40%, 20~30%, 30~61%, 30~50%, 30~40%, 40~61%, 40~50% or 50~
61%.According to the certain embodiments of the application, the weight summation of the alkene oxime amine and azoles fungicide accounts for the sterilization group
Close object gross weight 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%,
19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%,
34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%,
49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%,
64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%,
79%, 80% or 81%.
" insecticide-applying way " includes but not limited to known in the art of foliar spray, soil treatment, seed treatment etc.
What application method.Herein described active constituent or bactericidal composition can be given at any time.Such as the active constituent
Or bactericidal composition can be used before agricultural pest generation, when occurring or after occurring, such as can be occurred in pest and disease damage
It is preceding or occur after about 1 hour, about 2 hours, about 4 hours, about 5 hours, about 8 hours, about 12 hours, about 24 hours, about 2 days,
About 4 days, about 8 days, about 16 days, about 30 days or 1 month, dispenser in about 2 months.
Herein described bactericidal composition can also be used for multiple times with first use.When used multiple times the notch, can with
Every the mode dispenser of random time, for example, be divided between subsequent dose and preceding dosage about 8 weeks, about 4 weeks, about 2 weeks, about 1 week, about
5 days, about 3 days, about 2 days, about 24 hours, about 12 hours, about 8 hours, about 6 hours, about 4 hours, about 3 hours, about 2 hours, about 1
Hour, about 30 minutes or less time.
Herein described bactericidal composition can be used alone, and can also be used in mixed way with other suitable fungicide.Institute
State be used in mixed way can be used simultaneously with other fungicide or successively use.When in use, can be arbitrary with interval when priority
Between mode use.
The present composition can be prepared into the various dosage forms of suitable agricultural use by known method, and relatively good dosage form has
Aqueous suspension agent, dispersible oil-suspending agent, aqueous emulsion, microemulsion, wettable powder, suspension seed-coating agent, water dispersible granules, at seed
Manage dispersible pulvis, seed treatment microcapsule suspending agent or missible oil etc..
The present invention composition prepare when, can according to method known in those skilled in the art (such as《Pesticide
Formulation technology》, Liu Bulin chief editors, the preparation processing method involved in the second edition is hereby incorporated by reference).
When composition pesticide of the present invention is configured to suspending agent, auxiliary agent includes：Dispersant, thickener, is prevented wetting agent
Rotten agent, antifoaming agent, antifreezing agent and/or water etc..Wherein：Dispersant is selected from polycarboxylate salt dispersant, rosin dispersant, phosphate
Class dispersant, macromolecule emulsion dispersant, alkyl naphthalene sulfonic acid condensation polymer sodium salt, alkylnaphthalene sulfonate condensation polymer, ethyoxyl triphen
Vinylphenol phosphate, organophosphorus compounds, combed high-molecular copolymer, polyoxyethylene aryl ether, polyoxyethylene aryl phenyl ether
It is one or more in phosphate amine salt and styrene phenol polyoxyethylene anionic dispersing agents etc.；The dosage of the dispersant is
The 1-8% of total formulation weight, such as 2-7%, preferably 3-6%, such as 3-5%, 4-5% or 4-6%；Wetting agent is selected from alkyl phenol
The poly- base ether formaldehyde condensation products sulfate of polyoxyethylene, aryl sulfonate formaldehyde condensates, alkylnaphthalene sulfonate and anion soak
Agent composition, isopropyl naphthalene sulfonate, normal-butyl naphthalene sulfonate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyoxy
Vinyl ethers phosphate, alkyl sulfate, sulfosuccinate, ethoxy alcohol, block copolymer, polyxyethylated alcohol and fat
It is one or more in alcohol polyoxyethylene ether etc.；The dosage of the wetting agent be total formulation weight 1-6%, such as 2-5% or
3-4%, preferably 2-4%, such as 2-3% or 3-4%；The one kind of thickener in xanthans, aluminium-magnesium silicate and bentonite etc.
Or it is a variety of；The dosage of the thickener is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-
6%, preferably 1-5%, such as 2-4% or 1-3%；Preservative is selected from benzoic acid, sodium benzoate and BIT (1,2- benzisothiazoles
Quinoline -3- ketone) etc. in it is one or more；The dosage of the preservative be total formulation weight 0.1-10%, such as 1-9%,
0.1-5%, 0.5-5% or 1-5%, preferably 0.2-2%, such as 0.5-1% or 1-2%；Antifoaming agent is organic silicon antifoaming agent
Deng；The dosage of the antifoaming agent is the 0.1-10% of total formulation weight, such as 1-9%, 0.1-5%, 0.5-5% or 1-5% are excellent
Select 0.4-1.0%, such as 0.6-0.8%；Antifreezing agent is selected from ethylene glycol, propylene glycol, glycerine, urea and inorganic salts such as sodium chloride
It is one or more in；The dosage of the antifreezing agent is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-
8%, 1-7% or 1-6%, preferably 1-5%, such as 2-4% or 1-3%；And surplus is water.By pesticide combination of the present invention
When object is configured to wettable powder, the auxiliary agent includes：Dispersant, wetting agent and/or filler etc..Wherein：Dispersant is selected from
It is one or more in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate and alkylnaphthalene sulfonate formaldehyde condensation products etc.；Institute
The dosage for stating dispersant is the 1-10% of total formulation weight, such as 2-9%, 3-8% or 4-7%, preferably 3-7%, such as 4-6%
Or 5-6%；Wetting agent is one or more in alkyl sulfate, alkylsulfonate and naphthalene sulfonate etc.；The wetting agent
Dosage be total formulation weight 1-10%, such as 2-9%, 3-8% or 4-7%, preferably 3-7%, such as 4-6% or 5-6%；
And remaining is filler, one in diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite and clay etc.
Kind is a variety of.
When composition pesticide of the present invention is configured to water dispersible granules, the auxiliary agent includes dispersant, wetting agent, collapses
Solve agent, binder and/or filler etc..Wherein：Dispersant be selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate and
It is one or more in alkylnaphthalene sulfonate formaldehyde condensation products etc.；The dosage of the dispersant is the 1-10% of total formulation weight,
Such as 2-9%, 3-8% or 4-7%, preferably 3-7%, 4-6% or 5-6%；Wetting agent is selected from polyoxyethylene alcohol, alkylsurfuric acid
It is one or more in salt, alkylsulfonate and naphthalene sulfonate etc.；The dosage of the wetting agent is the 1-10% of total formulation weight,
Such as 2-9%, 3-8% or 4-7%, preferably 2-7%, such as 3-6% or 4-5%；Disintegrant be selected from ammonium sulfate, urea, sucrose,
It is one or more in glucose, citric acid, succinic acid and sodium bicarbonate etc.；The dosage of the disintegrant is total formulation weight
0.1-10%, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 1-5%, such as 2-4% or 1-3%；Binder
It is one or more in diatomite, cornstarch, PVA, carboxymethyl (ethyl) cellulose family and microcrystalline cellulose class etc.；Institute
The dosage for stating binder is the 0.1-10%, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6% of total formulation weight, preferably
1-5%, such as 2-4% or 1-3%；And remaining be filler, selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, sepiolite,
It is one or more in talcum powder, attapulgite and clay etc..
When composition pesticide of the present invention is configured to dispersible oil-suspending agent, the auxiliary agent includes dispersant, wetting
Agent, thickener, preservative, antifoaming agent, antifreezing agent and/or grease auxiliary agent etc..Wherein：Dispersant be selected from polycarboxylate salt dispersant,
Rosin dispersant, phosphoric acid ester dispersant, macromolecule emulsion dispersant, alkyl naphthalene sulfonic acid condensation polymer sodium salt, alkyl naphthalene sulfonic acid
Salt condensation polymer, ethyoxyl triphenylethylene phenol phosphate, organophosphorus compounds, combed high-molecular copolymer, polyoxyethylene aryl ether,
It is one or more in polyoxyethylene aryl phenyl ether phosphoric acid amine salt and styrene phenol polyoxyethylene anionic dispersing agents etc.；
The dosage of the dispersant is the 1-8% of total formulation weight, such as 2-7%, 1-7% or 2-8%, preferably 3-6%, such as 4-
5%；Wetting agent is selected from the poly- base ether formaldehyde condensation products sulfate of alkylphenol-polyethenoxy, aryl sulfonate formaldehyde condensates, alkyl
Naphthalene sulfonate and anion humectant mixture, isopropyl naphthalene sulfonate, normal-butyl naphthalene sulfonate, alkylphenol-polyethenoxy base ether
Phosphate, phenethyl phenol polyoxyethylene groups ether phosphate, alkyl sulfate, sulfosuccinate, ethoxy alcohol, block copolymerization
It is one or more in object, polyxyethylated alcohol and fatty alcohol polyoxyethylene ether etc.；The dosage of the wetting agent is total formulation weight
The 1-6% of amount, such as 2-5%, 1-5% or 1-4%, preferably 2-4%, such as 2-3% or 4-5%；Thickener be selected from xanthans,
It is one or more in aluminium-magnesium silicate and organobentonite etc.；The dosage of the thickener is the 0.1-10% of total formulation weight,
Such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 1-5%, such as 2-4%, 3-5% or 2-3%；Preservative selects
From one or more in benzoic acid, sodium benzoate and BIT (1,2-benzisothiazolin-3-one) etc.；The use of the preservative
Amount is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 0.2-2%, such as
0.5-1.5%, 1-1.5% or 1-2%；Antifoaming agent is organic silicon antifoaming agent etc.；The dosage of the antifoaming agent is total formulation weight
The 0.1-10% of amount, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 0.4-1.0%, for example, 0.6-0.8% or
0.5-1%；Antifreezing agent is one or more in ethylene glycol, propylene glycol, glycerine, urea and inorganic salts such as sodium chloride；
The dosage of the antifreezing agent is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6% are excellent
Select 1-5%, such as 2-4%, 3-5% or 2-3%；And remaining is grease analog assistant, selected from methyl oleate, vegetable oil, animal
It is one or more in oil etc..
Specific implementation mode
Following embodiment is only that the present invention is furture elucidated, without limiting the invention to these specific implementation modes
Intention.One skilled in the art would recognize that all present invention encompasses may include in Claims scope
Alternative, improvement project and equivalent program.
Inventor is by alkene oxime amine and benzoxazole, imazalil, cyazofamid or metconazole mixture, with cucumber powdery mildew's pathogen, Huang
Melon Pseudoperonospora cubensis, tomato early blight bacterium, Colletotrichum capsici, fusarium graminearum are object, carry out co-toxicity test, specifically
Test situation and result are as follows：
Medicament uses potting seedling measuring method to the joint toxicity measuring experiment of cucumber powdery mildew's pathogen.
The culture of cucumber powdery mildew's pathogen and the preparation of inoculation material：Never Huang was acquired with applying the cucumber cultivation of fungicide
Melon powdery mildew leaf, moisturizing is placed in 23 DEG C, is cultivated under the conditions of relative humidity=50%, 12h alternation of light and darkness in culture dish, pending
After generating a large amount of new spores on sick blade, spore is eluted with sterile water, is configured to a concentration of 105 spore/mL's
Spore suspension is used for inoculation test.
For trying the preparation of cucumber plant：By the cultivation of susceptible cucumber variety in a diameter of 15cm, the pot for growing seedlings of high 12cm, set
It is cultivated in glasshouse, after its length to 3-4 leaf phase, selects the consistent plant of growing way and tested.
Toxicity test of the medicament to cucumber powdery mildew's pathogen：Prepared graded series liquid hand sprayer will be shifted to an earlier date,
(pressure 1bar, nozzle diameter:It 0.3mm) uniformly sprays for trying cucumber plant blade surface, small droplet is covered with leaf table, but not
It can drip as standard.After liquid sprays, natural air drying.Each concentration is inoculated with 6 melon seedlings, 3 repetitions.It, will after dispenser for 24 hours
Prepared spore suspension even spraying is seeded in the true leaf surface of cucumber plant in advance.After moisturizing 12h, it is placed in daylight glass
It is cultivated in greenhouse.
As a result it investigates：According to National Standard of the People's Republic of China " pesticide field efficacy medicine test criterion (GB/T
Regulation in 17980.30-2000) " carries out classification and disease index investigation, is recorded by following stage division.
Stage division is as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less entire leaf area；
3 grades：Lesion area accounts for entire leaf area 6% -10%；
5 grades：Lesion area accounts for entire leaf area 11% -20%；
7 grades：Lesion area accounts for entire leaf area 21% -40%；
9 grades：Lesion area accounts for 40% or more entire leaf area.
Calculation formula：
Disease index may be simply referred to as disease and refer to.
Co-toxicity coefficient is the coefficient for evaluating the variation of virulence when two or more pesticide activity component is used with.
According to control effect, virulence regression equation and EC are found out50Value；Two are evaluated according to the abundant co-toxicity coefficient methods of Sun Yun (CTC)
The synergy type of kind active constituents of medicine difference mixed ratio：If co-toxicity coefficient is more than 120, show there is synergistic effect；If
Less than 80, it is shown to be antagonism；Between 80~120, it is shown to be summation action.
Calculation formula：
B in the TI × mixture of content (%)+B agent of A in TI × mixture of theoretical toxicity index (TTI)=A agent of mixture
Content (%)
Medicament uses potting seedling measuring method to the joint toxicity measuring experiment of bacterium of downy mildew of cucumber.To each proportioning test specimens
Product carry out the foliar spray processing of various concentration.The 2nd day inoculation cucumber downy mildew sporangia suspension, inoculation are placed on after processing
Phjytotron (condition：Temperature：25 DEG C of daytime, 20 DEG C of night, relative humidity：It 95-99%) cultivates, is placed on greenhouse (25 within 24 hours
DEG C ± 1 DEG C) normal management, investigation prevention effect after 6 days.
According to control effect, virulence regression equation and EC90 values are found out；Two are evaluated according to the abundant co-toxicity coefficient methods of Sun Yun (CTC)
The synergy type of kind active constituents of medicine difference mixed ratio：If co-toxicity coefficient is more than 120, show there is synergistic effect；If
Less than 80, it is shown to be antagonism；Between 80~120, it is shown to be summation action.
Calculation formula：
B in the TI × mixture of content (%)+B agent of A in TI × mixture of theoretical toxicity index (TTI)=A agent of mixture
Content (%)
Medicament uses bacterium to the joint toxicity measuring experiment of tomato early blight bacterium, Colletotrichum capsici, fusarium graminearum
Silk growth rate method is measured.The PDA culture medium melted is cooled to 60-70 DEG C, quantitative medicine is added by designed concentration
The toxic culture medium containing different pesticide solutions is made in agent, after it is fully cooled, inoculation diameter 5mm for trying pathogen bacterium
Piece is placed in culture (26 ± 1 DEG C) in incubator, is investigated after 7 days.Measured respectively when investigation each handle for try pathogen
Colony diameter calculates bacteriostasis rate according to the following formula.
Bacteriostasis rate (%)=(control colony diameter-processing colony diameter)/control colony diameter × 100%
According to bacteriostasis rate, virulence regression equation and EC are found out50Value；According to the abundant co-toxicity coefficient methods of Sun Yun (CTC), (this is science
Upper common formulation) two kinds of active constituents of medicine difference mixed ratios of evaluation synergy type：If co-toxicity coefficient is more than 120,
Show there is synergistic effect；If being less than 80, it is shown to be antagonism；Between 80~120, it is shown to be summation action.
Calculation formula：
B in the TI × mixture of content (%)+B agent of A in TI × mixture of theoretical toxicity index (TTI)=A agent of mixture
Content (%)
1. alkene oxime amine of table and benzoxazole and combinations thereof are to joint toxicity measuring result in cucumber powdery mildew's pathogen room
From table 1 it follows that alkene oxime amine and benzoxazole mixture have a higher activity to cucumber powdery mildew's pathogen, 11
EC for trial than mixture50Value is between 0.52mg/L-4.84mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and benzoxazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with benzoxazole mixture prevention powdery mildew of cucumber to close
Rationality and feasibility.
2. alkene oxime amine of table and benzoxazole and combinations thereof are to joint toxicity measuring result in tomato early blight bacterium room
| Medicament | Regression equation | EC50(mg/L) | Related coefficient | Co-toxicity coefficient |
| Alkene oxime amine | Y=4.6907+1.7215x | 1.51 | 0.9887 | - |
| Benzoxazole | Y=5.4726+1.6346x | 0.62 | 0.9867 | - |
| Alkene oxime amine:Benzoxazole=60:1 | Y=4.9014+1.5980x | 1.15 | 0.9732 | 128.3 |
| Alkene oxime amine:Benzoxazole=40:1 | Y=4.9154+1.5756x | 1.13 | 0.9714 | 129.1 |
| Alkene oxime amine:Benzoxazole=20:1 | Y=5.0186+1.4557x | 0.97 | 0.9653 | 145.7 |
| Alkene oxime amine:Benzoxazole=10:1 | Y=5.1008+1.4462x | 0.85 | 0.9861 | 157.1 |
| Alkene oxime amine:Benzoxazole=5:1 | Y=5.2631+1.4224x | 0.65 | 0.9803 | 187.5 |
| Alkene oxime amine:Benzoxazole=1:1 | Y=5.5410+1.7097x | 0.48 | 0.9952 | 183.1 |
| Alkene oxime amine:Benzoxazole=1:5 | Y=5.7517+1.7555x | 0.37 | 0.9893 | 185.8 |
| Alkene oxime amine:Benzoxazole=1:10 | Y=5.6883+1.8465x | 0.42 | 0.9892 | 156.0 |
| Alkene oxime amine:Benzoxazole=1:20 | Y=5.5153+1.4962x | 0.45 | 0.9735 | 141.8 |
| Alkene oxime amine:Benzoxazole=1:40 | Y=5.4996+1.5312x | 0.47 | 0.9814 | 133.8 |
| Alkene oxime amine:Benzoxazole=1:60 | Y=5.4664+1.5056x | 0.49 | 0.9827 | 127.8 |
From Table 2, it can be seen that alkene oxime amine and benzoxazole mixture have a higher activity to tomato early blight bacterium, 11
EC for trial than mixture50Value is between 0.37mg/L-1.15mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and benzoxazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has rationally with benzoxazole mixture prevention early blight of tomato
Property and feasibility.
3. alkene oxime amine of table and benzoxazole and combinations thereof are to joint toxicity measuring result in Colletotrichum capsici room
From table 3 it is observed that alkene oxime amine and benzoxazole mixture have a higher activity to Colletotrichum capsici, 11
EC for trial than mixture50Value is between 0.14mg/L-2.73mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and benzoxazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has rationally with benzoxazole mixture prevention pepper anthracnose
Property and feasibility.
4. alkene oxime amine of table and cyazofamid and combinations thereof are to joint toxicity measuring result in cucumber downy mildew room
| Medicament | Regression equation | EC50(mg/L) | Related coefficient | Co-toxicity coefficient |
| Alkene oxime amine | Y=3.9103+1.6096x | 4.75 | 0.9881 | - |
| Cyazofamid | Y=3.3349+1.7085x | 9.43 | 0.9894 | - |
| Alkene oxime amine:Cyazofamid=60:1 | Y=4.1949+1.3996x | 3.76 | 0.9805 | 127.4 |
| Alkene oxime amine:Cyazofamid=40:1 | Y=4.2022+1.3970x | 3.72 | 0.9807 | 129.3 |
| Alkene oxime amine:Cyazofamid=20:1 | Y=4.2581+1.3472x | 3.55 | 0.9830 | 137.0 |
| Alkene oxime amine:Cyazofamid=10:1 | Y=4.2313+1.4901x | 3.28 | 0.9863 | 151.7 |
| Alkene oxime amine:Cyazofamid=5:1 | Y=4.2399+1.5331x | 3.13 | 0.9881 | 165.4 |
| Alkene oxime amine:Cyazofamid=1:1 | Y=4.1689+1.3929x | 3.95 | 0.9869 | 159.9 |
| Alkene oxime amine:Cyazofamid=1:5 | Y=3.9696+1.5039x | 4.84 | 0.9839 | 167.4 |
| Alkene oxime amine:Cyazofamid=1:10 | Y=3.7849+1.6553x | 5.42 | 0.9737 | 159.7 |
| Alkene oxime amine:Cyazofamid=1:20 | Y=3.7083+1.6327x | 6.18 | 0.9862 | 145.8 |
| Alkene oxime amine:Cyazofamid=1:40 | Y=3.6215+1.6725x | 6.67 | 0.9898 | 138.1 |
| Alkene oxime amine:Cyazofamid=1:60 | Y=3.6796+1.5201x | 7.38 | 0.9796 | 125.7 |
As can be seen from Table 4, alkene oxime amine and cyazofamid mixture have a higher activity to bacterium of downy mildew of cucumber, 11
EC for trial than mixture50Value is between 3.13mg/L-7.38mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and cyazofamid
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has rationally with cyazofamid mixture prevention cucumber downy mildew
Property and feasibility.
5. alkene oxime amine of table and imazalil and combinations thereof are to joint toxicity measuring result in cucumber powdery mildew's pathogen room
As can be seen from Table 5, alkene oxime amine and imazalil mixture have a higher activity to cucumber powdery mildew's pathogen, 11
EC for trial than mixture50Value is between 1.43mg/L-5.35mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and imazalil
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with imazalil mixture prevention powdery mildew of cucumber to close
Rationality and feasibility.
6. alkene oxime amine of table and imazalil and combinations thereof are to joint toxicity measuring result in Colletotrichum capsici room
| Medicament | Regression equation | EC50(mg/L) | Related coefficient | Co-toxicity coefficient |
| Alkene oxime amine | Y=3.7818+1.6239x | 5.63 | 0.9854 | - |
| Imazalil | Y=6.1115+1.3633x | 0.15 | 0.9832 | - |
| Alkene oxime amine:Imazalil=60:1 | Y=4.4298+1.2873x | 2.77 | 0.9867 | 127.1 |
| Alkene oxime amine:Imazalil=40:1 | Y=4.5602+1.2918x | 2.19 | 0.9827 | 135.9 |
| Alkene oxime amine:Imazalil=20:1 | Y=4.6946+1.5753x | 1.56 | 0.9790 | 131.7 |
| Alkene oxime amine:Imazalil=10:1 | Y=5.1252+1.4794x | 0.82 | 0.9952 | 158.9 |
| Alkene oxime amine:Imazalil=5:1 | Y=5.3822+1.1954x | 0.48 | 0.9866 | 165.5 |
| Alkene oxime amine:Imazalil=1:1 | Y=5.7929+1.0438x | 0.17 | 0.9793 | 171.9 |
| Alkene oxime amine:Imazalil=1:5 | Y=6.1120+1.1724x | 0.11 | 0.9735 | 162.8 |
| Alkene oxime amine:Imazalil=1:10 | Y=6.0167+0.9735x | 0.09 | 0.9614 | 182.8 |
| Alkene oxime amine:Imazalil=1:20 | Y=6.0539+1.0682x | 0.10 | 0.9789 | 157.3 |
| Alkene oxime amine:Imazalil=1:40 | Y=6.0409+1.1477x | 0.12 | 0.9935 | 128.0 |
| Alkene oxime amine:Imazalil=1:60 | Y=6.0105+1.0686x | 0.11 | 0.9893 | 138.6 |
As can be seen from Table 6, alkene oxime amine and imazalil mixture have a higher activity to Colletotrichum capsici, 11
EC for trial than mixture50Value is between 0.09mg/L-2.77mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and imazalil
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with imazalil mixture prevention pepper anthracnose to close
Rationality and feasibility.
7. alkene oxime amine of table and metconazole and combinations thereof are to joint toxicity measuring result in fusarium graminearum room
As can be seen from Table 7, alkene oxime amine and metconazole mixture have a higher activity to fusarium graminearum, 11
EC for trial than mixture50Value is between 0.07mg/L-0.21mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and metconazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with metconazole mixture prevention wheat scab to close
Rationality and feasibility.
1, example of formulations
Percentage composition is mass percent in all formulations proportioning.
Embodiment 1：5% alkene oxime amine benzoxazole microemulsion (ME)
Weigh 2.5g alkene oxime amines active compound, 2.5g benzoxazole active compound, 5g N-Methyl pyrrolidones, 10g isopropanols, 4.5g
Agriculture breast 600#, 5.5g agriculture breast 1601#, adds water to complement to 100g.Active compound, solvent, emulsifier are added together, make to be dissolved into uniformly
Oil phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, oil phase is mixed with water, physical and chemical performance is made
Preferable microemulsion.
Embodiment 2：81% alkene oxime amine benzoxazole wettable powder (WP)
1g alkene oxime amines active compound, 80g benzoxazole active compound, 1g neopelexes, 10g sodium lignin sulfonates are weighed,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 3：61% alkene oxime amine benzoxazole water dispersible granules (WG)
Weigh the sodium salt of 1g alkene oxime amines active compound, 60g benzoxazole active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 14g ammonium sulfate,
2g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 17.6g cornstarch.It is uniformly mixed, through gas
It after stream crushes, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 4：41% alkene oxime amine benzoxazole missible oil (EC)
Weigh 1g alkene oxime amines active compound, 40g benzoxazole active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxyethylene
Ether 2g, nonylphenol polyoxyethylene ether 2g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 5：42% alkene oxime amine benzoxazole suspending agent (SC)
Weigh 2g alkene oxime amines active compound, 40g benzoxazole active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts wetting
Dispersant, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g have
Machine modified siloxane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and shear 10min,
After being sanded again with sand mill, suspending agent is obtained.
Embodiment 6：The 22% dispersible oil-suspending agent of alkene oxime amine benzoxazole (OD)
Weigh 2g alkene oxime amines active compound, 20g benzoxazole active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 7：24% alkene oxime amine benzoxazole aqueous emulsion (EW)
Weigh 4g alkene oxime amines active compound, 20g benzoxazole active compound, 150# solvent naphthas 24g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.5g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 4g Silwet 806 increase
Imitate agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：It is organically-modified
Siloxanes), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain water and milk
Agent.
Embodiment 8：10% alkene oxime amine benzoxazole microemulsion (ME)
Weigh 5g alkene oxime amines active compound, 5g benzoxazole active compounds, 5g N-Methyl pyrrolidones, 10g isopropanols, 4g agriculture breasts
600#, 6g agriculture breast 1602#, add water to complement to 100g.Active compound, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；
Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, oil phase is mixed with water, it is preferable that physical and chemical performance is made
Microemulsion.
Embodiment 9：30% alkene oxime amine benzoxazole suspending agent (SC)
Weigh 25g alkene oxime amines active compound, 5g benzoxazole active compounds, 5g rosins dispersion moisture agent, 1.5g polycarboxylic acid salts profit
Hygroscopic water powder, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g
Organically-modified silica alkane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 10：44% alkene oxime amine benzoxazole missible oil (EC)
Weigh 40g alkene oxime amines active compound, 4g benzoxazole active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxyethylene
Ether 2g, nonylphenol polyoxyethylene ether 1.5g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 11：21% alkene oxime amine benzoxazole microcapsule suspending agent (CS)
20g alkene oxime amines active compound, 1g benzoxazole active compounds are weighed, (Bao Lige Products, appear below Ultrazine NA
With herein) 1g, Sodium Polyacrylate 2g, polyureas performed polymer 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha
15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthans 0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent
In oil solvent, uniform oil-phase solution is obtained；Aqueous solution containing emulsified dispersant is added thereto, with being vigorously stirred, prepares
Go out using solid active compound, solvent naphtha as oil phase, using aqueous solution containing emulsified dispersant as the O/W type stable emulsions of water phase.It will be advance
Prepared urea-formaldehyde polyurea prepolymer is added in lotion, using low content hydrochloric acid regulating system pH value, in acid catalysed conditions
Lower generation polymerisation, makes oil phase substance be wrapped, and forms microcapsule suspending agent.Thickening is added into this microcapsule suspending agent
Agent, antifreeze, stir evenly to get microcapsule suspending agent.
Embodiment 12：61.5% alkene oxime amine benzoxazole water dispersible granules (WG)
Weigh the sodium salt of 60g alkene oxime amines active compound, 1.5g benzoxazole active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 28.5g cornstarch.It is uniformly mixed, warp
It after air-flow crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 13：12.2% alkene oxime amine benzoxazole granule (GR)
Weigh 12g alkene oxime amines active compound, 0.2g benzoxazole active compound, clay 50g, cornstarch 8g, white carbon 4g, lignin
Sodium sulfonate 1g, polylactic acid PLA 3g, 2g Arabic gum, 3.2g lauryl sodium sulfate add clay to complement to 100g.Add water 10g,
It is uniformly mixed, carries out extruder grain, dry granule product.
Embodiment 14：81% alkene oxime amine benzoxazole wettable powder (WP)
Weigh 80g alkene oxime amines active compound, 1g benzoxazole active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 15：24.3% alkene oxime amine imazalil suspending agent (SC)
Weigh 0.3g alkene oxime amines active compound, 24g imazalil active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts profit
Hygroscopic water powder, 0.3g xanthans, 1.5g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 16：30.5% alkene oxime amine Imazalil EC (EC)
Weigh 0.5g alkene oxime amines active compound, 30g imazalil active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxy second
Alkene ether 2g, nonylphenol polyoxyethylene ether 1.5g, 200# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, composition is made
Missible oil.
Embodiment 17：The 20.5% dispersible oil-suspending agent of alkene oxime amine imazalil (OD)
Weigh 0.5g alkene oxime amines active compound, 20g imazalils active compound, 17g TERMUL 3015 (nonionic surfactant),
5g TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added
To shearing 10min in high-shear emulsion machine, then after being sanded with sand mill, dispersible oil-suspending agent is obtained.
Embodiment 18：31.5% alkene oxime amine imazalil suspending agent (SC)
Weigh 1.5g alkene oxime amines active compound, 30g imazalil active compounds, 5.2g rosins dispersion moisture agent, 1.8g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 19：27.5% alkene oxime amine imazalil microcapsule suspending agent (CS)
Weigh 2.5g alkene oxime amines active compound, 25g imazalil active compounds, Ultrazine NA 1g, Sodium Polyacrylate 2g, polyureas
Performed polymer 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha 15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthan
Glue 0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent oil solvent, uniform oil-phase solution is obtained；
Aqueous solution containing emulsified dispersant is added thereto, with being vigorously stirred, makes using solid active compound, solvent naphtha as oil phase, with
Aqueous solution containing emulsified dispersant is the O/W type stable emulsions of water phase.Advance prepared urea-formaldehyde polyurea prepolymer is added
Enter in lotion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalyzed conditions, and oil phase substance is made to be wrapped
It wraps, forms microcapsule suspending agent.Thickener, antifreeze are added into this microcapsule suspending agent, stirs evenly to get microcapsule suspension
Agent.
Embodiment 20：60% alkene oxime amine imazalil water dispersible granules (WG)
Weigh the sodium salt of 10g alkene oxime amines active compound, 50g imazalils active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 30g bentonites.It is uniformly mixed, through air-flow
It after crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 21：30% alkene oxime amine imazalil suspending agent (SC)
Weigh 15g alkene oxime amines active compound, 15g imazalil active compounds, 6g sodium lignin sulfonates dispersion moisture agent, 1g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 22：18% alkene oxime amine imazalil aqueous emulsion (EW)
Weigh 15g alkene oxime amines active compound, 3g imazalils active compound, 150# solvent naphthas 18g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.2g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 806 synergy of 4gSilwet
Agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：Organic modified silicas
Oxygen alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 23：22% alkene oxime amine Imazalil EC (EC)
Weigh 20g alkene oxime amines active compound, 2g imazalil active compounds, calcium dodecyl benzene sulfonate 5.5g, phenethyl phenol polyoxy second
Alkene ether 1.5g, nonylphenol polyoxyethylene ether 1.5g, 150# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, combination is made
Object missible oil.
Embodiment 24：The 21% dispersible oil-suspending agent of alkene oxime amine imazalil (OD)
Weigh 20g alkene oxime amines active compound, 1g imazalils active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 25：41% alkene oxime amine imazalil water dispersible granules (WG)
Weigh the sodium salt of 40g alkene oxime amines active compound, 1g imazalils active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 49g cornstarch.It is uniformly mixed, through gas
It after stream crushes, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 26：5% alkene oxime amine Imazalil EC (EC)
4.918g alkene oxime amines active compound, 0.082g imazalil active compounds are weighed, calcium dodecyl benzene sulfonate 5g, phenethyl phenol are poly-
Ethylene oxide ether 2g, nonylphenol polyoxyethylene ether 1g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 27：81% alkene oxime amine imazalil wettable powder (WP)
Weigh 80g alkene oxime amines active compound, 1g imazalil active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 28：81% alkene oxime amine cyazofamid wettable powder (WP)
Weigh 1g alkene oxime amines active compound, 80g cyazofamid active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 29：61% alkene oxime amine cyazofamid suspending agent (SC)
Weigh 1g alkene oxime amines active compound, 60g cyazofamid active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts wetting
Dispersant, 0.3g xanthans, 1.5g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g
Organically-modified silica alkane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 30：24.6% alkene oxime amine cyazofamid missible oil (EC)
Weigh 0.6g alkene oxime amines active compound, 24g cyazofamid active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxy second
Alkene ether 2g, nonylphenol polyoxyethylene ether 1.5g, 200# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, composition is made
Missible oil.
Embodiment 31：The 21% dispersible oil-suspending agent of alkene oxime amine cyazofamid (OD)
Weigh 1g alkene oxime amines active compound, 20g cyazofamids active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 32：33% alkene oxime amine cyazofamid suspending agent (SC)
Weigh 3g alkene oxime amines active compound, 30g cyazofamid active compounds, 5g rosins dispersion moisture agent, 2g polycarboxylic acid salts wetting
Dispersant, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g have
Machine modified siloxane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and shear 10min,
After being sanded again with sand mill, suspending agent is obtained.
Embodiment 33：18% alkene oxime amine cyazofamid microcapsule suspending agent (CS)
Weigh 3g alkene oxime amines active compound, 15g cyazofamid active compounds, Ultrazine NA 1g, Sodium Polyacrylate 2g, polyureas is pre-
Aggressiveness 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha 15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthans
0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent oil solvent, uniform oil-phase solution is obtained；To
Aqueous solution containing emulsified dispersant is wherein added, with being vigorously stirred, makes using solid active compound, solvent naphtha as oil phase, to contain
The aqueous solution of emulsifying dispersant is the O/W type stable emulsions of water phase.It prepared urea-formaldehyde polyurea prepolymer will be added in advance
In lotion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalyzed conditions, and oil phase substance is made to be wrapped
Get up, forms microcapsule suspending agent.Thickener, antifreeze are added into this microcapsule suspending agent, stirs evenly to get microcapsule suspension
Agent.
Embodiment 34：40% alkene oxime amine cyazofamid water dispersible granules (WG)
Weigh 20g alkene oxime amines active compound, 20g cyazofamids active compound, 5g sodium lignin sulfonates, 4g ammonium sulfate, 0.6g alkylnaphthalenes
Sulfonate and anion humectant mixture, 0.4g sodium benzoates and 50g bentonites.It is uniformly mixed, after air-flow crushing, is making
It is granulated in grain machine, then dries, sieves up to granular product.
Embodiment 35：30% alkene oxime amine cyazofamid suspending agent (SC)
Weigh 25g alkene oxime amines active compound, 5g cyazofamid active compounds, 6g sodium lignin sulfonates dispersion moisture agent, 1g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 36：11% alkene oxime amine cyazofamid aqueous emulsion (EW)
Weigh 10g alkene oxime amines active compound, 1g cyazofamids active compound, 150# solvent naphthas 11g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.2g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 806 synergy of 4gSilwet
Agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：Organic modified silicas
Oxygen alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 37：63% alkene oxime amine cyazofamid missible oil (EC)
Weigh 60g alkene oxime amines active compound, 3g cyazofamid active compounds, calcium dodecyl benzene sulfonate 5.5g, phenethyl phenol polyoxy second
Alkene ether 1.5g, nonylphenol polyoxyethylene ether 1.5g, 150# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, combination is made
Object missible oil.
Embodiment 38：The 20.5% dispersible oil-suspending agent of alkene oxime amine cyazofamid (OD)
Weigh 20g alkene oxime amines active compound, 0.5g cyazofamids active compound, 17g TERMUL 3015 (nonionic surfactant),
5g TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added
To shearing 10min in high-shear emulsion machine, then after being sanded with sand mill, dispersible oil-suspending agent is obtained.
Embodiment 39：54.9% alkene oxime amine cyazofamid water dispersible granules (WG)
Weigh the sodium salt of 54g alkene oxime amines active compound, 0.9g cyazofamids active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 35.1g cornstarch.It is uniformly mixed, warp
It after air-flow crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 40：5% alkene oxime amine cyazofamid missible oil (EC)
4.938g alkene oxime amines active compound, 0.062g cyazofamid active compounds are weighed, calcium dodecyl benzene sulfonate 5g, phenethyl phenol are poly-
Ethylene oxide ether 2g, nonylphenol polyoxyethylene ether 1g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 41：81% alkene oxime amine metconazole wettable powder (WP)
Weigh 1g alkene oxime amines active compound, 80g metconazole active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 42：61% alkene oxime amine metconazole suspending agent (SC)
Weigh 1g alkene oxime amines active compound, 60g metconazole active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts wetting
Dispersant, 0.3g xanthans, 1.5g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g
Organically-modified silica alkane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 43：24.6% alkene oxime amine metconazole missible oil (EC)
Weigh 0.6g alkene oxime amines active compound, 24g metconazole active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxy second
Alkene ether 2g, nonylphenol polyoxyethylene ether 1.5g, 200# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, composition is made
Missible oil.
Embodiment 44：The 21% dispersible oil-suspending agent of alkene oxime amine metconazole (OD)
Weigh 1g alkene oxime amines active compound, 20g metconazoles active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 45：33% alkene oxime amine metconazole suspending agent (SC)
Weigh 3g alkene oxime amines active compound, 30g metconazole active compounds, 5g rosins dispersion moisture agent, 2g polycarboxylic acid salts wetting
Dispersant, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g have
Machine modified siloxane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and shear 10min,
After being sanded again with sand mill, suspending agent is obtained.
Embodiment 46：18% alkene oxime amine metconazole microcapsule suspending agent (CS)
Weigh 3g alkene oxime amines active compound, 15g metconazole active compounds, Ultrazine NA 1g, Sodium Polyacrylate 2g, polyureas is pre-
Aggressiveness 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha 15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthans
0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent oil solvent, uniform oil-phase solution is obtained；To
Aqueous solution containing emulsified dispersant is wherein added, with being vigorously stirred, makes using solid active compound, solvent naphtha as oil phase, to contain
The aqueous solution of emulsifying dispersant is the O/W type stable emulsions of water phase.It prepared urea-formaldehyde polyurea prepolymer will be added in advance
In lotion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalyzed conditions, and oil phase substance is made to be wrapped
Get up, forms microcapsule suspending agent.Thickener, antifreeze are added into this microcapsule suspending agent, stirs evenly to get microcapsule suspension
Agent.
Embodiment 47：40% alkene oxime amine metconazole water dispersible granules (WG)
Weigh 20g alkene oxime amines active compound, 20g metconazoles active compound, 5g sodium lignin sulfonates, 4g ammonium sulfate, 0.6g alkylnaphthalenes
Sulfonate and anion humectant mixture, 0.4g sodium benzoates and 50g bentonites.It is uniformly mixed, after air-flow crushing, is making
It is granulated in grain machine, then dries, sieves up to granular product.
Embodiment 48：30% alkene oxime amine metconazole suspending agent (SC)
Weigh 25g alkene oxime amines active compound, 5g metconazole active compounds, 6g sodium lignin sulfonates dispersion moisture agent, 1g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 49：11% alkene oxime amine metconazole aqueous emulsion (EW)
Weigh 10g alkene oxime amines active compound, 1g metconazoles active compound, 150# solvent naphthas 11g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.2g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 806 synergy of 4gSilwet
Agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：Organic modified silicas
Oxygen alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 50：63% alkene oxime amine metconazole missible oil (EC)
Weigh 60g alkene oxime amines active compound, 3g metconazole active compounds, calcium dodecyl benzene sulfonate 5.5g, phenethyl phenol polyoxy second
Alkene ether 1.5g, nonylphenol polyoxyethylene ether 1.5g, 150# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, combination is made
Object missible oil.
Embodiment 51：The 20.5% dispersible oil-suspending agent of alkene oxime amine metconazole (OD)
Weigh 20g alkene oxime amines active compound, 0.5g metconazoles active compound, 17g TERMUL 3015 (nonionic surfactant),
5g TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added
To shearing 10min in high-shear emulsion machine, then after being sanded with sand mill, dispersible oil-suspending agent is obtained.
Embodiment 52：54.9% alkene oxime amine metconazole water dispersible granules (WG)
Weigh the sodium salt of 54g alkene oxime amines active compound, 0.9g metconazoles active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 35.1g cornstarch.It is uniformly mixed, warp
It after air-flow crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 53：5% alkene oxime amine metconazole missible oil (EC)
4.938g alkene oxime amines active compound, 0.062g metconazole active compounds are weighed, calcium dodecyl benzene sulfonate 5g, phenethyl phenol are poly-
Ethylene oxide ether 2g, nonylphenol polyoxyethylene ether 1g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
2 field control effectiveness tests
2.1 different embodiments prevent powdery mildew of cucumber field control effectiveness test
Experiment carries out in Shouguang City of Shandong Province heliogreenhouse, and preceding stubble is Chinese cabbage, and cucumber spacing in the rows is 30cm, and line-spacing is
60cm.Experiment sets 49 processing, 30 square metres of plot area；Often processing is repeated 3 times, totally 147 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Disease investigation, early stage dispenser, dispenser 2 times, be spaced 7 days, before first time medicine, before second of dispenser, second
Disease index is investigated respectively within 7 days after secondary dispenser.5 points of investigation are taken at random per cell, are seted the tone per solid point and are looked into two plants, depending on incidence
Every plant is investigated whole blades from bottom to top, records the sick numbers of sheets at different levels, and severity Scaling takes 0,1,3,5,7,9 totally six ranks.Point
Grade standard is as follows：
0 grade：It is disease-free；
1 grade：Scab accounts for 5% or less leaf area；
3 grades：Scab accounts for leaf area 6%~10%；
5 grades：Scab accounts for leaf area 11%~25%；
7 grades：Scab accounts for leaf area 26%~50%；
9 grades：Scab accounts for 50% or more leaf area.
Drug effect computational methods：
In formula：CK0--- disease index before blank district dispenser；CK1--- disease index after blank district dispenser；
PT0--- disease index before chemicals treatment district dispenser；PT1--- the state of an illness after chemicals treatment district dispenser.
Safety observations：Influence of each chemicals treatment district of visual observations to cucumber growth in 1,3,7 day after each medicine, clearly has
No poisoning occurs.Test result and analysis：
The different embodiments of table 8 are to powdery mildew of cucumber field control effect
Alkene oxime amine single dose is slightly below imazalil, benzoxazole, metconazole list to the preventive effect of powdery mildew of cucumber as shown in Table 8
Agent is higher than cyazofamid single dose.Have compared to single dose to the preventive effect of powdery mildew of cucumber by each embodiment after compounding and obviously carries
Height, the control effect for compounding the bactericidal composition of mixture are generally higher by than the control effect of any one separate constituent
10% or more.It is apparent to illustrate that alkene oxime amine and imazalil, benzoxazole, cyazofamid, metconazole compounding have powdery mildew of cucumber
Synergistic effect.Field is estimated, and within the range of experimental dose, normal for examination cucumber growth, each treatment agent does not occur to cucumber
Poisoning phenomenon.
2.2 different embodiments prevent cucumber downy mildew field control effectiveness test
Experiment carries out in the heliogreenhouse of Tai'an Daiyue District room villages and small towns.It is experimental field sandy loam, rich water is sufficient.Cucumber is
August is just colonized, 80 centimetres of big row, 50 centimetres of small row, 35 centimetres of spacing in the rows, double ridge duplicate rows cultivations.Experiment sets 49 processing, cell face
30 square metres of product；Often processing is repeated 3 times, totally 147 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Disease investigation, in cucumber downy mildew early stage first time dispenser, second of dispenser after 7 days, altogether dispenser 2 times.The
7 days investigation state of an illness after 7 days and second of medicine after dispenser.5 points of investigation are taken at random per cell, and every is looked into two plants, depending on feelings of falling ill
Every plant of condition investigates 5~15 leaves (investigation determines that identical leaf position is investigated from bottom to top per cell every time) from bottom to top, records each
The sick number of sheets of grade, severity Scaling take 0,1,3,5,7,9 totally six ranks.Grade scale is as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 10% or less entire leaf area；
3 grades：Lesion area accounts for entire leaf area 10%~20%；
5 grades：Lesion area accounts for entire leaf area 21%~30%；
7 grades：Lesion area accounts for entire leaf area 31%~50%；
9 grades：Lesion area accounts for 50% or more entire leaf area.
Drug effect computational methods
Test results and analysis
The different embodiments of table 9 are to cucumber downy mildew field control effect
Alkene oxime amine single dose is slightly below cyazofamid single dose to the preventive effect of cucumber downy mildew as shown in Table 9, higher than imazalil, nitrile
Benzene azoles, metconazole single dose.It is all significantly improved compared to single dose to the preventive effect of cucumber downy mildew by each embodiment after compounding,
The control effect for compounding the bactericidal composition of mixture is generally higher by 10% than the control effect of any one separate constituent
More than.Illustrate that alkene oxime amine has apparent synergy with imazalil, benzoxazole, cyazofamid, metconazole compounding to cucumber downy mildew
Effect.Field is estimated, and within the range of experimental dose, normal for examination cucumber growth, each treatment agent does not occur the medicine to cucumber
Evil phenomenon.
2.3 different embodiments prevent early blight of tomato field control effectiveness test
Experimental plot is located at the Senior Residents in Fengxian District of Shanghai towns Zhuan Hang, and topography is flat, and irrigation and drainage are convenient.It is tomato for examination vegetables, kind is
Zhejiang powder 202.Experiment sets 49 processing, 30 square metres of plot area；Often processing is repeated 3 times, and totally 147 cells, cell are arranged at random
Row.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Investigation method, time and number：First time dispenser before the onset of early blight of tomato, second of dispenser after 7 days, altogether dispenser
2 times.7 days investigation state of an illness after 7 days and second of medicine after first time dispenser.5 points of investigation are taken at random per cell, and every is looked into two plants, often
Strain divides upper, middle and lower to investigate 10 leaves, accounts for the percentage of entire leaf area with the lesion area on every a piece of leaf to be classified.
Stage division (as unit of blade)：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less blade area；
3 grades：Lesion area accounts for the 6%-10% of blade area；
5 grades：Lesion area accounts for the 11%-25% of blade area；
7 grades：Lesion area accounts for the 26%-50% of blade area；
9 grades：The percentage that lesion area accounts for blade area is more than 50%.
Drug effect computational methods：
In formula：CK1--- disease index after blank district dispenser；PT1--- disease index after chemicals treatment district dispenser；
To the other influences of crop
Whether observation crop has poisoning generation, should also record other beneficial effects to crop.
Test result and analysis
The different embodiments of table 10 are to early blight of tomato field control effect
Alkene oxime amine single dose is to the preventive effect of early blight of tomato and imazalil, benzoxazole, metconazole single dose as shown in Table 10
Preventive effect is suitable, is higher than cyazofamid single dose.Have compared to single dose to the preventive effect of early blight of tomato by each embodiment after compounding
It significantly improves, the control effect for compounding the bactericidal composition of mixture is more universal than the control effect of any one separate constituent
It is higher by 10% or more.It is bright to illustrate that alkene oxime amine and imazalil, benzoxazole, cyazofamid, metconazole compounding have early blight of tomato
Aobvious synergistic effect.Field is estimated, and within the range of experimental dose, normal for examination tomato growth, each treatment agent does not occur pair
The poisoning phenomenon of tomato.
2.4 different embodiments prevent pepper anthracnose field control effectiveness test
Experiment is middle green pepper No. 4 for examination capsicum variety in Jining City in Shandong Province Jinxiang County.Experiment sets 49 processing, cell face
30 square metres of product；Often processing is repeated 3 times, totally 147 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Disease investigation, dispenser before the onset of pepper anthracnose, dispenser 2 times are spaced 7 days, 7 days after first time medicine, second
Disease index is investigated within 7 days after dispenser respectively, calculates control effect.5 points of investigation are taken at random per cell, and 50 fruits are taken per cell,
The percentage that entire fruit area is accounted for lesion area is classified, and severity Scaling takes 0,1,3,5,7,9 totally six ranks.Point
Grade standard is as follows：
0 grade：It is disease-free；
1 grade：Scab accounts for 2% or less fruit area；
3 grades：Scab accounts for the 3%~8% of fruit area；
5 grades：Scab accounts for the 9%~15% of fruit area；
7 grades：Scab accounts for the 16%~25% of fruit area；
9 grades：Scab accounts for 25% or more of fruit area.
Drug effect computational methods：
In formula：CK1--- disease index after blank district dispenser；PT1--- disease index after chemicals treatment district dispenser；
To the other influences of crop
Whether observation crop has poisoning generation, should also record other beneficial effects to crop.
Test result and analysis：
The different embodiments of table 11 are to pepper anthracnose field control effect
Alkene oxime amine single dose is to the preventive effect of pepper anthracnose and imazalil, benzoxazole, metconazole single dose as shown in Table 11
Preventive effect is suitable, is higher than cyazofamid single dose.Have compared to single dose to the preventive effect of pepper anthracnose by each embodiment after compounding
It significantly improves, the control effect for compounding the bactericidal composition of mixture is more universal than the control effect of any one separate constituent
It is higher by 10% or more.It is bright to illustrate that alkene oxime amine and imazalil, benzoxazole, cyazofamid, metconazole compounding have pepper anthracnose
Aobvious synergistic effect.Field is estimated, and within the range of experimental dose, normal for examination chili growth, each treatment agent does not occur pair
The poisoning phenomenon of capsicum.
2.5 different embodiments prevent wheat scab field control effectiveness test
Experiment is to raise wheat 13 for examination wheat breed in the Guichi District of Chizhou City, Anhui Province villages Mei Li, preceding stubble be one season semilate rice, it is small
Wheat planting type broadcasts sowing for rotary tillage.The soil of all experimental plots, cultivation are horizontal consistent with fertilizer and water management.Experiment is set at 24
Reason, 30 square metres of plot area；Often processing is repeated 3 times, totally 72 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state) by market purchase gained.
Wheat is in flowering initial stage when experiment, and flowering accounts for about 5-10%, and dispenser 2 times is spaced 10 days, mu spouting liquid 30L.End
Incidence is managed in investigation everywhere when 22 days head blight stable diseases after secondary medicine, as unit of fringe, per the 5 points of samplings of cell diagonal line,
Every 100 fringes of investigation, look into 500 fringes altogether, count sick spike number and are classified to sick fringe, calculate preventive effect.Disease scale standard is as follows：
0 grade：It does not fall ill；
1 grade：Morbidity spikelet number accounts for 1/4 or less total spikelet number；
2 grades：Morbidity spikelet number accounts for total spikelet number 1/4~1/2；
3 grades：Morbidity spikelet number accounts for total spikelet number 1/2~3/4；
4 grades：Morbidity spikelet number accounts for 3/4 or more total spikelet number.
Drug effect computational methods：
To the other influences of crop
Whether observation crop has poisoning generation, should also record other beneficial effects to crop.
Test result and analysis：
The different embodiments of table 12 are to wheat scab field control effect
Alkene oxime amine single dose is to the preventive effect of wheat scab and imazalil, benzoxazole, metconazole single dose as shown in Table 12
Preventive effect is substantially suitable.It is all significantly improved compared to single dose to the preventive effect of wheat scab by each embodiment after compounding, it is multiple
The control effect of the bactericidal composition with mixture than the control effect of any one separate constituent be generally higher by 10% with
On.Illustrate that alkene oxime amine has apparent synergistic effect with imazalil, benzoxazole, metconazole compounding to wheat scab.Field
Range estimation, within the range of experimental dose, normal for examination wheat growth, each treatment agent does not occur the poisoning phenomenon to wheat.
It can be seen that bactericidal composition generation of the present invention has the beneficial effect that：
(1) compared with single dose, which has synergistic effect to disease, improves bactericidal effect；
(2) dosage and drug cost for lowering single dose, reduce environmental pollution and pesticide residue；
(3) composition is made of the active ingredient of different role mechanism, and action site increases, and is conducive to overcome and delay disease
The generation of bacterium drug resistance.
Above in association with illustratively illustrating present embodiments.Those skilled in the art are according to this disclosure
Content be readily apparent that, can each embodiment suitably be adjusted and be reconfigured according to actual needs, without
Spirit and scope can be detached from.The protection domain of the application is subject to following claims.
Claims (11)
1. a kind of composition pesticide, the composition pesticide is containing there are two types of active components：Active components A is alkene oxime amine, activity
Ingredient B is one or more in benzoxazole, imazalil, cyazofamid, metconazole, and active constituent B preferably is selected from metconazole, nitrile benzene
It is one or more in azoles.
2. composition pesticide according to claim 1, which is characterized in that the active components A:The weight of active constituent B
Portion rate is 1:80~80:1, preferably 1:60~60:1, preferably 1:20~20:1.
3. according to the composition pesticide described in any one of claim 1-4, which is characterized in that active components A and activity at
The 5%-81%, preferably 10%-61% for dividing the weight summation of B to account for composition gross weight.
4. composition pesticide according to any one of claim 1-3, which is characterized in that the composition pesticide is outstanding for water
Floating agent, dispersible oil-suspending agent, aqueous emulsion, microemulsion, wettable powder, suspension seed-coating agent, water dispersible granules, seed treatment can
Dispersion powder, seed treatment microcapsule suspending agent or missible oil.
5. composition pesticide according to claim 4, which is characterized in that the composition pesticide is for foliar spray, kind
Subprocessing or soil treatment.
6. the composition pesticide described in a kind of any one of claim 1-5 is used for the purposes of controlling plant diseases.
7. purposes according to claim 6, which is characterized in that the plant disease be by sac fungus, basidiomycetes, oomycetes and
Fungi Imperfecti fungi causes, preferably cucumber downy mildew, powdery mildew, anthracnose, scab, tomato late blight, leaf mold, early epidemic
Disease, gray mold, western melon powdery mildew, anthracnose, blight dis-ease, droop, downy mildew of garpe, anthracnose, powdery mildew, anthrachose of grape,
White rot, gray mold, alternaria leaf spot of apple, brown spot, scab, ring spot, anthracnose, melon and pepper anthracnose, epidemic disease
Disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice sheath blight disease, bakanae disease, maize sheath blight, silk
Smut, the late blight of potato, early blight.
8. a kind of method of controlling plant diseases, which is characterized in that by the pesticide combination described in any one of claim 1-5
Object is applied to Cereal, fruit tree, vegetables and industrial crops planting area, with controlling plant diseases.
9. according to the method described in claim 8, it is characterized in that, the plant disease be by sac fungus, basidiomycetes, oomycetes and
Fungi Imperfecti fungi causes, preferably cucumber downy mildew, powdery mildew, anthracnose, scab, tomato late blight, leaf mold, early epidemic
Disease, gray mold, western melon powdery mildew, anthracnose, blight dis-ease, droop, downy mildew of garpe, anthracnose, powdery mildew, anthrachose of grape,
White rot, gray mold, alternaria leaf spot of apple, brown spot, scab, ring spot, anthracnose, melon and pepper anthracnose, epidemic disease
Disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice sheath blight disease, bakanae disease, maize sheath blight, silk
Smut, the late blight of potato, early blight.
10. according to the method described in claim 9, it is characterized in that, the component of the composition pesticide be configured to preparation application,
Or the mixed application of bucket.
11. a kind of method preparing the composition pesticide as described in any one of claim 1-5, which is characterized in that described
Method is by the active components A, active constituent B and agriculturally acceptable carrier or auxiliary agent mix.
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