CN103392715A - Sterilization composition containing cyprodinil and captan - Google Patents
Sterilization composition containing cyprodinil and captan Download PDFInfo
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- CN103392715A CN103392715A CN2013103234317A CN201310323431A CN103392715A CN 103392715 A CN103392715 A CN 103392715A CN 2013103234317 A CN2013103234317 A CN 2013103234317A CN 201310323431 A CN201310323431 A CN 201310323431A CN 103392715 A CN103392715 A CN 103392715A
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Abstract
The invention discloses a sterilization composition containing cyprodinil and captan and relates to a sterilization composition containing the cyprodinil and the captan which serve as active components. The invention also relates to application of the sterilization composition containing the cyprodinil and the captan in prevention and treatment of bacteria harmfulness to frumentum, fruits, vegetables, flowers, lawns and economical crops. The sterilization composition containing the cyprodinil and the captan is characterized by comprising the active components, namely the cyprodinil and the captan, wherein the weight ratio of the cyprodinil to the captan is (1:100)-(100:1). The sterilization composition formed by mixing the cyprodinil and the captan has the advantages that a prevention and treatment effect is enhanced, the bacteriocidal spectrum is expanded, and a function of realizing multiple effects with one drug is realized; furthermore, the working mechanisms of the cyprodinil and the captan are different, so that a disease resistance effect can be enhanced, and the drug resistance of germs is low.
Description
Technical field
A kind of bactericidal composition that contains cyprodinil and captan of the present invention relates to is a kind of cyprodinil (Cyprodinil) and captan (Captan) bactericidal composition as active component that comprises.The invention still further relates to a kind of bactericidal composition that comprises cyprodinil and captan and prevent and treat the purposes of the germ harm of cereal, fruit, vegetables, flowers, lawn, economic crops.
Background technology
In horticultural crop and dry-land crop production, crop can run into multiple fungi or infecting of bacterium and various diseases, also often because of in soil multiple cause a disease or saprophytic fungi (as mould in corruption, epidemic disease is mould, Rhizoctonia solani Kuhn, sickle-like bacteria, botrytis cinerea etc.) and bacterium (soft-rot fungi etc.) infect harm, cause rotten kind, rotten, seedling extremely.
Cyprodinil (Cyprodinil), its chemical name is: 4-cyclopropyl-6-methyl-N-phenyl pyrimidine-2-amine, its structural formula is:
Cyprodinil is the aminopyrimidine bactericide, is the methionine biosynthesis inhibitor.Same triazole type, imidazoles, morpholine class, phenylpyrrole class etc. are without cross resistance.Have protection, treatment, blade penetrates and the root systemic activity, but foliar spray or seed treatment also can be done the medication of barley seed coat agent.Be applicable to wheat, barley, grape, strawberry, fruit tree, vegetables, ornamental plants etc., be mainly used in preventing and treating gray mold, powdery mildew, scab, be full of rot and wheat eyeprint disease etc.
Captan (captan), the Chinese another name is called Gai Pudan, and its chemical name is: N-(trichloro-methylthio)-hexamethylene-4-alkene-1,2-dicarboximide; 1,2,3,6-tetrahydrochysene-N-(trichloro-methylthio) phthalimide, its structural formula is:
Captan is a kind of organic sulfur class broad spectrum activity low toxicity bactericide; take protective effect as main, have certain therapeutic action concurrently, use safer; many kinds of fungal diseases on various crop are all had good preventive effect, be specially adapted to the crop to copper agent agricultural chemicals sensitivity.This medicine is permeable to the cell membrane of germ, not only can disturb germ respiratory, but also can disturb its cell division, have a plurality of bactericidal actions site, continuous several times uses extremely difficulty to induce germ to develop immunity to drugs, and sprays continuously protection effect more obvious.It mainly makes spray application, also can make seed treatment, dips product after results, carries out soil treatment before sowing or before planting.Generally with 0.1% left and right concentration liquid spraying, the scab of control fruit tree, vegetables, flowers and other economic crops etc., downy mildew, powdery mildew, anthracnose, gray mold, early blight, late blight etc.The 0.3-0.5% that presses seed weight processes seed, can prevent and treat Cereal smut, disease in cotton seedling stage etc.The activity of this compound is good, and still, it is sometimes also unsatisfactory when low rate of application.
Summary of the invention
The objective of the invention is for solving above-mentioned at least one problem or its at least one aspect, in particular for effectively controlling plant disease, and/or reduce costs or application dosage,, through the large number of biological test screen, provide a kind of bactericidal composition that contains cyprodinil and captan and uses thereof.
The present invention relates to a kind of bactericidal composition that contains cyprodinil and captan.
A kind of bactericidal composition that contains cyprodinil and captan of the present invention and uses thereof is to take following technical scheme to realize:
A kind of bactericidal composition that contains cyprodinil and captan, is characterized in that containing active component cyprodinil and captan.
The present invention is a kind of, and to contain cyprodinil and captan in the bactericidal composition of cyprodinil and captan be the Synergistic effective dose, the weight proportion that the present invention is a kind of contains active component cyprodinil described in the bactericidal composition of cyprodinil and captan and captan is that 1:100 is to 100:1, preferred 1:50-50:1, preferred 1:20-20:1 again, more preferably 1:10-10:1, most preferably 1:5-5:1.
In a kind of bactericidal composition that contains cyprodinil and captan of the present invention, the weight percentage that described active component cyprodinil and captan account for composition is 5-90%, preferred 10%-80%, more preferably 20%-60%.
In described a kind of bactericidal composition that contains cyprodinil and captan, described active component cyprodinil and captan mix with liquid or solid carrier and/or surfactant.
Above-mentioned a kind of bactericidal composition that contains cyprodinil and captan of the present invention can only comprise active ingredient, also can mix together with additive, therefore a kind of bactericidal composition that contains cyprodinil and captan of the present invention can be prepared into various formulations, and the formulation of described bactericidal composition is suspending agent, seed coat agent, wetting powder, water dispersible granules, micro-capsule granules, paste, aerosol, ZC, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
A kind of bactericidal composition that contains cyprodinil and captan is characterized in that: also comprise one or more other active components.
A kind of bactericidal composition that contains cyprodinil and captan of the present invention is used for preventing and treating cereal, fruit, vegetables, flowers, lawn, economic crops.
The bactericidal composition that the present invention is a kind of contains cyprodinil and captan is for the protection of the purposes of plant propagation material and the plant organ that grows subsequently.
The place control soil that the bactericidal composition that a kind of use of the present invention contains cyprodinil and captan is applied to required control causes a disease or the purposes of saprophytic fungus and bacterium.
Detailed Description Of The Invention
The invention provides a kind of bactericidal composition with synergistic function that contains cyprodinil and captan.
The present invention creatively unites two into one cyprodinil and captan, not only can prevent and treat the germ harm of cereal, fruit, vegetables, flowers, lawn, economic crops, can also doublely control the fungus and bacterium disease in soil, have a medicine multiplex, widen the diseases prevention spectrum.And be used for soil treatment or soak (mixing) and plant, can prevent rotten kind that soil disease causes, rotten, ensure full stand, alleviate sprout term disease, better effects if.
The invention provides a kind of bactericidal composition that contains cyprodinil and captan.
Concrete scheme of the present invention is: a kind of bactericidal composition that contains active component cyprodinil and captan is comprised of following component: the suspending agent that cyprodinil, captan bactericide and insecticides adjuvant form, seed coat agent, wetting powder, water dispersible granules, micro-capsule granules, paste, aerosol, ZC, coated granule, extrude granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
In composition of the present invention, cyprodinil bactericide and captan bactericide are the Synergistic effective dosies, in the present composition, the weight proportion of compound cyprodinil and captan is 1:100-100:1, preferred 1:50-50:1, preferred 1:20-20:1 again, more preferably 1:10-10:1, most preferably 1:5 is to 5:1.
In composition of the present invention, active component cyprodinil and captan bactericide account for the 5-90% of composition, preferred 10%-80%, more preferably 20-60%.
Above-mentioned composition of the present invention can only comprise active ingredient, also can mix together with additive, therefore composition of the present invention can be prepared into various formulations, the liquor that forms such as cyprodinil, captan bactericide and insecticides adjuvant, wetting powder, water dispersible granules, suspending agent, seed coat agent, aerosol, coated granule, effervescent tablet, aqueous emulsion, microemulsion etc.According to the character of these compositions and use purpose and the ambient conditions that composition will reach, can select composition is used with spraying, immersion, atomizing, the method for broadcasting sowing, pour, filling with root etc. and so on.
Can produce these preparations by known method.For example, in the situation that selectively use surfactant, by reactive compound is mixed and prepares preparation with filler, described filler is the diluent or carrier of liquid or liquid gas or solid, said surfactant is emulsifier, dispersant, wetting agent.In the situation that water, as filler, also can with an organic solvent, for example, be used as cosolvent with organic solvent.
According to the present invention, term " carrier " refer to can be with reactive compound combined or associating so that it is easier to be administered to the natural or synthetic organic or inorganic compound of object (for example plant, crop or careless class).Therefore, described carrier is preferably inertia, should be at least agricultural acceptable.Described carrier can be solid or liquid.
In the present invention, operable nonactive medium can be both that solid can be also liquid, can be used as for example having that the solid media material uses: the phyteral powdery type (particle of soybean meal, starch, grain dust, wood powder, bark powder, sawdust, walnut shell powder, wheat bran, cellulose powder, coconut husk, corncob and tobacco stem for example, extract residue after plant essence etc.), paper, sawdust, pulverize synthesized polymer body, clay class (such as kaolin, bentonite, acid china clay etc.), the talcum powder class of synthetic resin etc.Silica (for example diatomite, silica sand, mica, moisture silicic acid, calcium silicates), chemical fertilizer, the clay fertilizer of active carbon, natural mineral matter class (float stone, attapulgite and zeolite etc.), the inorganic mineral powder of firing diatomite, sand, plastics medium etc. (such as polyethylene, polypropylene, polyvinylidene chloride etc.), potassium chloride, calcium carbonate, calcium phosphate etc., ammonium sulfate, ammonium phosphate, urea, greening ammonium etc., these materials can use separately or be mixed more than 2 kinds.
can be used as can selecting of liquid media materials'use in following material, water for example, alcohol type (methyl alcohol for example, ethanol, isopropyl alcohol, butanols, ethylene glycol etc.), ketone (acetone for example, methyl ethyl ketone, isobutyrone, cyclohexanone etc.), ethers (ether for example, dioxanes, methylcellulose, oxolane etc.), aliphatic hydrocarbon class (kerosene for example, the mineral wet goods), aromatic hydrocarbons class (benzene for example, toluene, dimethylbenzene, solvent naphtha, Fluhyzon, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbon, chlorobenzene, Deng), the halogenated hydrocarbon class, amide-type, the sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, the animal wet goods.
As other adjuvants can carry out choice for use according to application target, also can use separately, some occasion more than 2 kinds adjuvant share, or some occasion can not used adjuvant fully.for making the emulsification of active ingredient compound, disperse, solubilization, and/or the wetting surfactant that can use for example can be enumerated fatty alcohol-polyoxyethylene ether, polyoxyethylene alkylaryl ether, the polyoxyethylene high-grade aliphatic ester, the phosphate of polyoxyethylene alcohol or phenol, the fatty acid ester of polyalcohol, the alkane aromatic sulfonic acid, the naphthalene sulfonic acids polymer, lignosulfonates, a dress copolymer of macromolecule comb shape, butyl naphthalene sulfonate, alkylaryl sulfonates, the alkyl sodium sulfosuccinate, grease, fatty alcohol and ethylene oxide condensate, the polyacrylates such as alkyltaurate, protein hydrolysate.Suitable oligosaccharide thing or polymer, for example based on the combination of independent vinyl monomer, acrylic acid, EO and/or PO or itself and for example (polynary) alcohol or (polynary) amine.
, for making active ingredient compound decentralized stabilization, adhering to and/or combination, can use such as adjuvants such as xanthans, aluminium-magnesium silicate, gelatin, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid (as cephalin and lecithin) and synthetic phospholipid, bentonite, sodium lignin sulfonates.
The optional spent glycol of antifreezing agent wherein, propane diols, glycerine, sorbierite.Can use adjuvant such as naphthalene sulfonic acids polymer, polymeric phosphate etc. as the deflocculant of suspension product.
Defoamer can use silicone defoaming agent.
Operable colouring agent, inorganic pigment for example, as iron oxide, titanium oxide and Prussian blue; And organic pigment/dyestuff: alizarin dyes, azo dyes and metal phthalocyanine dyestuff; And trace element, for example molysite, manganese salt, boron salt, mantoquita, cobalt salt, molybdenum salt and zinc salt.
Randomly, also can comprise other annexing ingredient, for example protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent, stabilizing agent, screening agent.
described a kind of formulation that contains the composition pesticide of cyprodinil and captan is: aerosol, suspending agent, the micro-capsule granula, granula subtilis, concentrate can flow, the ready to use solution agent, pulvis, aqueous emulsion, oil emu, fine granule, the oil dispersion powder, the miscible mobility concentrate of oil, the miscible liquid of oil, foaming agent, paste, suspending concentrate, suspension emulsion, solubility concentrates thing, soluble powder, granule, water-soluble granular and/or tablet, water solube powder, wetting powder, natural or synthetic material through the reactive compound dipping, microcapsules in polymeric material and water-dispersible granule.In preferred embodiments, described composition pesticide is suspending agent, water dispersible granules, wetting powder, suspension emulsion and/or microcapsule suspending agent.
Described preparation of the present invention can mix described reactive compound to prepare with conventional additives by known way.Described conventional additives such as conventional extender and solvent or thinner, emulsifier, dispersant and/or adhesive or fixative, wetting agent, waterproofing agent, if necessary, can also comprise drier and colouring agent, stabilizing agent, pigment, defoamer, preservative, thickener, water and other processing aid.
These compositions not only comprise and can be applicable to immediately pending object as spraying or dusting equipment by suitable equipment, but also be included in, are applied to the concentrated business composition that need dilute before object.
Composition of the present invention can be made the preparation that is suitable for using with the form of the composition of its active compound component, also can use with the form of the combination of the commodity preparation of its suitable dosage.
Composition of the present invention can also be co-administered with other active component, such as fungicide, bactericide, attractant, insecticide, miticide, nematocide, growth regulator, weed killer herbicide, safener, fertilizer or semiochemical etc. of described other active component.
Composition of the present invention or combination can also be presented as the form of kit, and it comprises cyprodinil and captan.On the other hand, the invention still further relates to described kit and be used for preventing and treating the germ harm of cereal, fruit, vegetables, flowers, lawn, economic crops.The invention still further relates to described kit for the protection of plant propagation material and the plant organ that grows subsequently.The invention still further relates to the place control soil that described kit is applied to required control causes a disease or saprophytic fungus and bacterium.
Described a kind of composition pesticide that contains cyprodinil and captan is used for preventing and treating cereal, fruit, vegetables, flowers, lawn, economic crops.common germ has stem canker, leaf rust, smut, bunt, rust, stem rot, gray mold, southern blight, anthracnose, bud rot, Brown patch disease, huge pinta, fairy ring, red thread, false smut, spot defoliation, leaf spot, epidemic disease, head blight, downy mildew, banded sclerotial blight, powdery mildew, phytophthora rot, anthracnose, brown spot, tar spot, balck shank, soft rot, canker, purple spot, damping off, stem wilt, damping off, the seedling epidemic disease, leaf blight, rust, black spot, scab.
Can use the useful plant of bactericidal composition of the present invention to comprise a lot, for example: paddy rice, peanut, cotton, beet, potato, lawn, wheat, barley, cucumber, grape, mango, wax-apple, strawberry, apple, banana, tomato, sunflower, pears, potato, corn, pear tree, coffee, ornamental plants class.
Described a kind of composition pesticide that comprises cyprodinil and captan is used for prevention or controls multiple causing a disease or the purposes of saprophytic fungus and bacterium in soil.the example of soilborne fungoid disease substance comprises Alternaria (Alternaria spp.), Ascochyta (Ascochyta spp.), Botrytis cinerea (Botrytis cinerea), Cercospora (Cercospora spp.), ergot (Claviceps purpurea), standing grain cochliobolus (Cochliobolus sativus), Colletotrichum (colletotrichum spp.), Epicoccum (Epicoccum spp.), F.graminearum schw (Fusarium graminearum), rice is disliked seedling chain spore (Fusarium moniliforme), fusarium oxysporum (Fusarium oxysporum), fusarium moniliforme (Fusarium proliferatum), fusariun solani (Fusarium solani), dimension glue chain spore (Fusarium subglitinans), Helminthosporium (Helminthosporium spp), avenge rotten microtorr bacterium (Microdochium nivale), Penicillium (Pencillium spp), Phoma (Phoma spp.), wheat class nuclear cavity bacteria (Pyrenophora graminea), rice blast Pyricularia Sacc. (Pyricularia oryzae), Rhizoctonia solani Kuhn (Rhizoctonia solani), Rhizoctonia cerealis (Rhizoctonia cerealis), Sclerotinia (Sclerotinia spp.), Septoria (Septoria spp.), , silk axle smut (Sphacelotheca reilliana), Tilletia (Tilletia spp.), meat spore core coral bacterium (Typhula incarnate), hidden smut (Urocystis occulta), Ustilago (Ustilago spp.) or Verticillium (Verticillium spp.).
The soil germ has rhizoctonia solani, sickle-like bacteria, pythium spp, phytophthora, the bacterium of dampinging off, root rot, pythium spp, botrytis cinerea, soft-rot fungi etc.In the ordinary course of things, the soil germ can produce a large amount of thalline, the host is susceptible as long as condition is grown favourable to pathogen growth, germ just can also can be infected the host by amount reproduction, under susceptible host existed, these germs just can enter the lasting pathogenic phase, the amount reproduction diffusion along with the continuous cropping of crop, but nutrient has been consumed or soil condition when as unfavorable to germ in temperature, humidity etc. afterwards, and germ can enter resting stage again.When susceptible host does not exist, the soil-borne disease bacterium also can survive in soil under, except the soil germ has widely host range, can also survive on non-host's root surface or the broken branches and fallen leaves, have saprophytic competitive ability with it and be undivided.But different germs are discrepant, as sickle-like bacteria, almost can survive indefinite duration in soil.
The soil of said plant or cultivation medium refer to the supporter that can make crops take root, grow when using method of the present invention is implemented, for example: soil, water etc., concrete raw material can use such as sand, float stone, vermiculite, diatomite, agar-agar, gelling material, polymer substance, asbestos, wood chip, bark etc.
To the method for using medicament in soil, for example be diluted in liquid preparation in water or do not dilute the root that directly is applied to plant corpus or the medium method in rice seedling bed that seedling is used, method in the rice seedling bed of the root of plant corpus or seedling that granule is disseminated to have prior to seeding pulvis, water dispersible granules etc. is sprayed in soil and with the whole method of mixing of soil, to be sprayed in implantation hole, seed furrow after pulvis, water-dispersible grain dilution agent before sowing or before the serike body, in the method for sowing etc.
Described a kind of composition pesticide that comprises cyprodinil and captan is for the protection of the purposes of plant propagation material and the plant organ that grows subsequently.
Term " plant propagation material " is interpreted as the plant part that refers to that all have fertility, seed for example, and it can be used for the breeding latter, and vegetable matter for example cuttage bar or stem tuber (for example potato).Therefore, plant part used herein comprises plant propagation material.What can mention is seed (narrowly) for example, root, fruit, stem tuber, bulb, rhizome and plant part.After germinateing from soil or the germination plant that suppresses after emerging and effectively plant also can mention.Immature plant can be undertaken all by dipping before transplanting or Local treatment is protected.
Plant part and the plant organ that grows subsequently are for example any parts of the plant of seed generation of oily plant propagation material.Plant part, plant organ and plant also can be benefited from the cause of disease infringement protection that obtains by composition pesticide being applied to plant propagation material.In embodiment, the plant organ that grows after certain plants part and some institute also can be regarded plant propagation material as, himself can use with composition pesticide (or processing); Thereby also can be benefited from the cause of disease infringement protection that obtains by composition pesticide being applied to certain plants part and certain plants organ by plant, other plant part and other plant organ that treated plant part and treated plant organ produce.
Preferably, propagating materials is seed, the method of seed treatment, for example can there are, the medicament of diluent liquid or solid shape or need not dilute directly is immersed in seed in liquid condition solution the method that makes medicament soak into seed, solid chemicals or liquid preparation is mixed with seed, carries out Cotton seeds and makes the surface of the seed adhere to the method for medicament, the method such as sprays when planting near seed.
Method of the present invention also provides with separately, successively or the co-administered described reactive compound of simultaneous system.In one embodiment, use simultaneously cyprodinil and captan.In another embodiment, use successively cyprodinil and captan.In another embodiment, separate administration cyprodinil and captan.
In a preferred embodiment, method of the present invention comprises the present composition that comprises cyprodinil and captan is administered to object.
Bactericidal composition of the present invention can be made into common medicament form, medicament forms such as missible oil, wetting powder, suspending agent, liquor, granule, seed coat agent is used, its amount of application, according to mixing ratio, meteorological condition, the medicament form of active ingredient, use period, application process, use place, prevent and kill off the target pest, the difference of target crops etc. and variant:
-usually for leaf section, process: 0.1-10000g/ha, preferred 10-1000 g/ha, more preferably 50-300 g/ha; For dipping or for instiling and using, described dosage even can also reduce, particularly when using inert base such as asbestos or pearl rock;
-for seed treatment: 2-200 g/100kg seed, preferred 3-150 g/100kg seed;
-for soil treatment: 0.1-10000 g/ha, preferred 1-5000 g/ha.
Above-mentioned dosage is only general exemplary dose, and during actual using, those skilled in the art can, according to actual conditions and needs, especially adjust rate of application according to the character of pending plant or crop and the seriousness of germ.
Should be pointed out that on meaning of the present invention, term " cyprodinil and captan combination/associating " comprises and separates, uses successively or simultaneously cyprodinil and captan.Preferably, described cyprodinil and captan are combined as the form of the composition that comprises cyprodinil and captan.
A kind of bactericidal composition that contains cyprodinil and captan of the present invention and uses thereof, cyprodinil and captan is composite, has synergistic function, not only can prevent and treat the germ harm of cereal, fruit, vegetables, flowers, lawn, economic crops, can also doublely control the fungus and bacterium disease in soil, have a medicine multiplex, widen the diseases prevention spectrum.And be used for soil treatment or soak (mixing) and plant, can prevent rotten kind that soil disease causes, rotten, ensure full stand, alleviate sprout term disease, better effects if.
Embodiment
Example of formulations
Embodiment 1 water dispersible granules
Cyprodinil 1%
Captan 50%
Polyvinyl alcohol 5%
Lauryl sodium sulfate 7%
Sodium lignin sulfonate 11%
Kaolin complements to 100%
Above-mentioned substance is evenly mixed, grinds, mixes suitable quantity of water and granulation, namely obtain said preparation after drying.
Embodiment 2 wetting powders (gross weight of preparation is 100 parts)
Cyprodinil 50%
Captan 10%
Alkylnaphthalene sulfonate formaldehyde condensation products 5%
Sodium alkyl benzene sulfonate 3%
Sodium lignin sulfonate 11%
Kaolin complements to 100%
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain said preparation.
Embodiment 3 suspending agents (gross weight of preparation is 100 parts)
Cyprodinil 50%
Captan 1%
Propane diols 5%
Phosphoric acid ester 3.5%
Xanthans 0.2%
Dioctyl sodium sulfosuccinate 0.7%
Water complements to 100%
Take according to the above ratio and have the high microbicide compositions of synergistic effect and prepare material, load weighted above-mentioned raw material except xanthans is fully mixed, after sand mill grinds, mix at a certain proportion of xanthans with configuring, obtain said preparation.
Embodiment 4 wetting powders (gross weight of preparation is 100 parts)
Cyprodinil 0.5%
Captan 50%
Alkylnaphthalene sulfonate formaldehyde condensation products 5%
Alkyl polyoxyethylene ether sulfonate 4%
NONIN HS 240 3%
(8-9 moles of ethylene oxide)
Kaolin complements to 100%
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain said preparation.
Embodiment 5 water dispersible granules (gross weight of preparation is 100 parts)
Cyprodinil 20%
Captan 1%
Polyvinyl alcohol 5%
Lauryl sodium sulfate 7%
Sodium lignin sulfonate 11%
Kaolin complements to 100%
Above-mentioned substance is evenly mixed, grinds, mixes suitable quantity of water and granulation, namely obtain said preparation after drying.
Embodiment 6 wetting powders (gross weight of preparation is 100 parts)
Cyprodinil 2%
Captan 40%
Alkylnaphthalene sulfonate formaldehyde condensation products 5%
Alkyl polyoxyethylene ether sulfonate 4%
NONIN HS 240 3%
(8-9 moles of ethylene oxide)
Kaolin complements to 100%
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain said preparation.
Embodiment 7 wetting powders (gross weight of preparation is 100 parts)
Cyprodinil 20%
Captan 40%
Alkylnaphthalene sulfonate formaldehyde condensation products 5%
Alkyl polyoxyethylene ether sulfonate 4%
NONIN HS 240 3%
(8-9 moles of ethylene oxide)
Kaolin complements to 100%
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain said preparation.
Embodiment 8 water dispersible granules (gross weight of preparation is 100 parts)
Cyprodinil 20%
Captan 10%
Polyvinyl alcohol 5%
Lauryl sodium sulfate 7%
Sodium lignin sulfonate 6%
Kaolin complements to 100%
Above-mentioned substance is evenly mixed, grinds, mixes suitable quantity of water and granulation, namely obtain said preparation after drying.
Embodiment 9 seed coat agents (gross weight of preparation is 100 parts)
Cyprodinil 5%
Captan 50%
Propane diols 5%
Phosphoric acid ester 3.5%
Xanthans 0.2%
Dioctyl sodium sulfosuccinate 0.7%
Water complements to 100%
Take according to the above ratio and have the high microbicide compositions of synergistic effect and prepare material, load weighted above-mentioned raw material except xanthans is fully mixed, after sand mill grinds, mix at a certain proportion of xanthans with configuring, obtain said preparation.
Embodiment 10 aerosols (gross weight of preparation is 100 parts)
Cyprodinil 50%
Captan 5%
Propane diols 5%
Phosphoric acid ester 3.5%
The castor oil of ethoxylation (EL-40) 2.0%
Solvesso 100 complements to 100%
At first with the antifreezing agent propane diols, thinner SOLVESSO 100 mixes, and adds cyprodinil and captan under stirring; Surfactant is added wherein, under agitation by a breaking plant colloid mill, pulverize, will be by the suspension after colloid mill, then through a micronizer.Move in circles to till the particle diameter≤2um of solids.
Embodiment 11 ZC
Atlox 4913 4%
Citric acid 0.05%
Catalyzer 0.1%
Water 13%
Cyprodinil 10%
PAPI 1.35%
Solvesso 200 10%
Atlox4913 16%
Dispersant LFH 0.3%
Defoamer 0.16%
Urea 8.4%
Captan 50%
Water complements to 100%
With PAPI, the oil phase that captan and Solvesso 100 form adds in the aqueous solution that contains Atlox4913, forms emulsion.Then heat and be incubated 50
oAdded catalyst reaction under C 2 hours.Obtain the microcapsules of captan after cooling.Atlox 4913, dispersant LFH, and defoamer, urea, cyprodinil and water mix in proportion, and, through sand milling, are prepared into suspending agent.The microcapsules of the captan that obtains is added in the aqueous suspension agent of cyprodinil, stir and obtain 10% cyprodinil+50% captan ZC.
Embodiment 12 extrudes granule
Cyprodinil 45%
Captan 45%
Sodium lignin sulfonate 4%
Carboxymethyl cellulose 2%
Kaolin complements to 100%
Active component is mixed with auxiliary agent and ground, the mixture water-wet.This mixture is extruded, then dry in air stream.
Embodiment 13 coated granules
Cyprodinil 20%
Captan 60%
Polyethylene glycol 3%
The silicic acid 1% of high degree of dispersion
Calcium carbonate complements to 100%
In blender, levigate active component evenly is applied to by on the wetting carrier of polyethylene glycol.Can obtain dustless coated granule in this way.
Embodiment 14 missible oil
Cyprodinil 50%
Captan 0.5%
Ethoxylated castor oil 10%
Calcium dodecyl benzene sulfonate 6%
Solvesso 100 complements to 100%
, with active ingredient, auxiliary agent and the stirring solvent phase to transparent and homogeneous, namely obtain missible oil.
Embodiment 15 effervescent tablets
Cyprodinil 1%
Captan 4%
Polyvinyl alcohol 2.0 %
Sodium Laurylsulfate 4.0%
Calcium carbonate 5.0%
White carbon complements to 100%
Above-mentioned substance is evenly mixed, grinds, mixes suitable quantity of water and granulation, namely obtain said preparation after drying.
Embodiment 16 pastes
Cyprodinil 5%
Captan 5%
Lignosulfonates 10.0%
Octyl phenol polyglycol ether (11-14 moles of ethylene oxide) 5.0%
Water complements to 100%
Above-mentioned substance is mixed to homogeneous phase, namely obtain paste.
Embodiment 17 microemulsions
Cyprodinil 20.0 %
Captan 20.0%
Polyvinyl alcohol 10.0 %
Calcium dodecyl benzene sulfonate 5.0%
Water complements to 100%
After being stirred, above-mentioned substance obtains the solution of clear.
Embodiment 18 aqueous emulsions
Cyprodinil 15%
Captan 5.0 %
1-METHYLPYRROLIDONE 15.0%
Ethoxylated castor oil 4.0%
Calcium dodecyl benzene sulfonate 3.0%
Water complements to 100%
Cyprodinil, captan are dissolved in 1-METHYLPYRROLIDONE fully, add in the solution of ethoxylated castor oil, calcium dodecyl benzene sulfonate, obtain aqueous emulsion after high shear.
Above embodiment proportioning is the weight per distribution ratio.
The stripped synergy test of biological test example is measured
Calculate the toxicity index of each medicament and the co-toxicity coefficient of mixture (CTC value) according to the abundant method of Sun Yun, when CTC≤80, compositions table reveals antagonism, when 80＜CTC＜120, compositions table reveals summation action, and when CTC 〉=120, compositions table reveals synergistic effect.
Actual measurement toxicity index (ATI)=(standard medicament EC50/ reagent agent EC50) * 100
The percentage composition of B in the percentage composition of A+B medicament toxicity index * mixture in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/theoretical toxicity index (TTI) * 100 of mixture
Test one: the toxicity test of wheat powdery mildew
Be selected from three to four consistent leaf phase wheat seedlings of growing way, each processing selects 3 basins for the examination wheat seeding, and in the spraying of 50PSI pressure column, the about 5mL of every basin, each medicament arrange 12 concentration gradients with the potter spray tower.After chemicals treatment, 24h connects bacterium, the wheat powdery mildew leaf that picks up from field is evenly shaken off conidium inoculate above wheat seedling, then wheat seeding is put into greenhouse and cultivates.Morbidity grade scale complete stool according to wheat powdery mildew after 7d is investigated disease index, and calculates control efficiency, then with method of least squares, calculates concentration EC in inhibition
50, then according to the abundant method of Sun Yun, calculate co-toxicity coefficient (CTC).
Table one: the virulence test result of the present invention on the control wheat powdery mildew
From table one as can be known, cyprodinil and captan are in the scope of the proportioning 1:100 ~ 100:1 of control wheat powdery mildew the time, co-toxicity coefficient is all greater than 120, illustrate that both all show as gain effect at being mixed in this scope, especially when both ratio was in 1:5, gain effect was particularly outstanding.
Test two: the toxicity test of potato cinerea
Be selected from the consistent potato set of growing way, each processing selects 3 basins for examination leaf seedling, and in the spraying of 50PSI pressure column, the about 5mL of every basin, each medicament arrange 12 concentration gradients with the potter spray tower.After chemicals treatment, 24h connects bacterium, the potato cinerea leaf that picks up from field is evenly shaken off conidium inoculate above potato set, then potato set is put into greenhouse and cultivates.Morbidity grade scale complete stool according to potato cinerea after 7d is investigated disease index, and calculates control efficiency, then with method of least squares, calculates concentration EC in inhibition
50, then according to the abundant method of Sun Yun, calculate co-toxicity coefficient (CTC).
Table two: the virulence test result of the present invention on the control potato cinerea
From table two as can be known, cyprodinil and captan are in the scope of the proportioning 1:100 ~ 100:1 of control potato cinerea the time, co-toxicity coefficient is all greater than 120, illustrate that both all show as gain effect at being mixed in this scope, especially when both ratio was in 5:1, gain effect was particularly outstanding.
Test three: the toxicity test of cucumber fusarium axysporum
Be selected from the consistent cucumber leaf seedling of growing way, each processing selects 3 basins for examination leaf seedling, and in the spraying of 50PSI pressure column, the about 5mL of every basin, each medicament arrange 12 concentration gradients with the potter spray tower.After chemicals treatment, 24h connects bacterium, the sick leaf of the cucumber of picking up from field is evenly shaken off conidium inoculate above cucumber seedling, then the cucumber leaf seedling is put into greenhouse and cultivates.Morbidity grade scale complete stool according to cucumber fusarium axysporum after 7d is investigated disease index, and calculates control efficiency, then with method of least squares, calculates concentration EC in inhibition
50, then according to the abundant method of Sun Yun, calculate co-toxicity coefficient (CTC).
Table three: the virulence test result of the present invention on the control cucumber fusarium axysporum
From table three as can be known, cyprodinil and captan are in the scope of the proportioning 1:100 ~ 100:1 of control cucumber fusarium axysporum the time, and co-toxicity coefficient, all greater than 120, illustrates that both all show as gain effect at being mixed in this scope, especially when both ratio was in 1:1, gain effect was particularly outstanding.
Test four
When the effect of active compound combinations surpasses the summation of the effect when each reactive compound is used separately, there is synergistic function.The predictive role of the particular combination of two kinds of reactive compounds can use so-called " Colby formula " (referring to S.R. Colby, " Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) following calculating: if
X be when use consumption as mg/ha or concentration the activity during as the reactive compound A of mppm;
Y be when use consumption as ng/ha or concentration the activity during as the reactive compound B of nppm, be expressed as the percentage that accounts for untreated control;
E be when use consumption as m and n g/ha or concentration the activity during as the reactive compound A of m and n ppm and B,
So
If the activity of actual observation (O) is greater than expection active (E), said composition [l1], namely have synergistic effect so.
Following biological test example is in order to illustrate the present invention.But the present invention is not limited to these embodiment.
Prolection to potato cinerea
With the aqueous suspension spraying of the leaf of potted plant potato set with the activity compound concentration with above appointment.The spore suspension of the plant inoculating potato cinerea that second day will be processed.Then basin is placed in the chamber with high atmospheric humidity (90-95%) under 20-22oC 24 hours.During inferior, spore-germination and germ tube infiltrate in leaf texture.Second day, be back to test plants in greenhouse and cultivated other 7 days under 20-220C atmospheric humidity relative to 65-70%.Then estimate the degree of botrytis cinerea development on leaf.
Claims (15)
1. a bactericidal composition that contains cyprodinil and captan, is characterized in that: contain active component cyprodinil and captan.
2. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: described active component cyprodinil and captan weight proportion are 1:100-100:1.
3. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight proportion of described active component cyprodinil and captan is: 1:50-50:1.
4. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight proportion of described active component cyprodinil and captan is: 1:20-20:1.
5. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight proportion of described active component cyprodinil and captan is: 1:10-10:1.
6. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight proportion of described active component cyprodinil and captan is: 1:5-5:1.
7. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight percentage that described active component cyprodinil and captan account for described composition is 5%-90%.
8. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight percentage that described active component cyprodinil and captan account for described composition is 10%-80%.
9. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: the weight percentage that described active component cyprodinil and captan account for described composition is 20%-60%.
10. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1, it is characterized in that: described active component cyprodinil and captan mix with liquid or solid carrier and/or surfactant.
11. a kind of bactericidal composition that contains cyprodinil and captan according to claim 1 is characterized in that: the formulation of described bactericidal composition is suspending agent, seed coat agent, wetting powder, water dispersible granules, micro-capsule granules, paste, aerosol, ZC, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
12. a kind of bactericidal composition that contains cyprodinil and captan according to any one in aforementioned claim is characterized in that: also comprise one or more other active components.
13. a kind of purposes of the bactericidal composition of cyprodinil and captan for the germ harm that prevents and treats cereal, fruit, vegetables, flowers, lawn, economic crops that contain claimed in claim 1.
14. a kind of bactericidal composition that contains cyprodinil and captan claimed in claim 1 is for the protection of the purposes of plant propagation material and the plant organ that grows subsequently.
15. the described a kind of bactericidal composition that contains cyprodinil and captan of claim 1 is applied to the purposes of the pathogenic or saprophytic fungus and bacterium of the place control soil of required control.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107372548A (en) * | 2017-08-02 | 2017-11-24 | 广东广康生化科技股份有限公司 | Composition pesticide containing captan and fluorine azoles ring bacterium amine and application thereof |
| CN107593738A (en) * | 2017-10-16 | 2018-01-19 | 广东广康生化科技股份有限公司 | A kind of composition pesticide containing captan and metrafenone |
| CN108041055A (en) * | 2018-01-12 | 2018-05-18 | 广东广康生化科技股份有限公司 | A kind of microbicide compositions containing captan and volution bacterium amine |
| CN108353916A (en) * | 2018-01-12 | 2018-08-03 | 广东广康生化科技股份有限公司 | Include bactericidal composition and its application of captan |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099220A (en) * | 1993-06-28 | 1995-03-01 | 希巴-盖吉股份公司 | A plant-microbicidal composition having synergistic action, comprising at least two active ingredient components, eherein...... |
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2013
- 2013-07-30 CN CN201310323431.7A patent/CN103392715B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099220A (en) * | 1993-06-28 | 1995-03-01 | 希巴-盖吉股份公司 | A plant-microbicidal composition having synergistic action, comprising at least two active ingredient components, eherein...... |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107372548A (en) * | 2017-08-02 | 2017-11-24 | 广东广康生化科技股份有限公司 | Composition pesticide containing captan and fluorine azoles ring bacterium amine and application thereof |
| CN107593738A (en) * | 2017-10-16 | 2018-01-19 | 广东广康生化科技股份有限公司 | A kind of composition pesticide containing captan and metrafenone |
| CN108041055A (en) * | 2018-01-12 | 2018-05-18 | 广东广康生化科技股份有限公司 | A kind of microbicide compositions containing captan and volution bacterium amine |
| CN108353916A (en) * | 2018-01-12 | 2018-08-03 | 广东广康生化科技股份有限公司 | Include bactericidal composition and its application of captan |
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