CN103719109A - Fungicidal composition - Google Patents
Fungicidal composition Download PDFInfo
- Publication number
- CN103719109A CN103719109A CN201310724597.XA CN201310724597A CN103719109A CN 103719109 A CN103719109 A CN 103719109A CN 201310724597 A CN201310724597 A CN 201310724597A CN 103719109 A CN103719109 A CN 103719109A
- Authority
- CN
- China
- Prior art keywords
- boscalid
- dimethomorph
- fungicidal composition
- fungicidal
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a fungicidal composition and particularly relates to the fungicidal composition containing active components such as boscalid and dimethomorph. The fungicidal composition contains active components such as boscalid and dimethomorph, wherein the weight ratio of boscalid to dimethomorph is 1:100-100:1; the content of boscalid and dimethomorph accounts for 5%-90% of the fungicidal composition. The fungicidal composition has the advantages that binary combination is carried out on boscalid and dimethomorph, so that the obtained fungicidal composition has the gain effect on the prevention and control effect, expands the fungicidal spectrum and plays a role in multiple effects with one product. In addition, since the action mechanisms of boscalid and dimethomorph are different, the disease prevention effect can be improved and the germs hardly generate pesticide resistance.
Description
Technical field
What the present invention relates to is a kind of Fungicidal composition, relates in particular to a kind of Fungicidal composition that contains active component Boscalid and dimethomorph.
Background technology
Dimethomorph (dimethomorph, chemical name (E, Z)-4-[3-(4-chlorphenyl) 3-(3,4-Dimethoxyphenyl) acryloyl] morpholine.Be single-minded ovicidal Gammaproteobacteria fungi bactericide, its effect feature is to destroy the formation of cell envelope, and there is to effect in each stage of oomycetes history of life, particularly responsive at the formation stages of sporangiophore and egg spore.Be widely used in vegetables downy mildew, epidemic disease, seedling stage damping off, black shank etc. by the fungus-caused disease control of Mastigomycotina Oomycete, tool systemic activity.Dimethomorph is used and has higher resistance risk separately, thus the composite uses of protective fungicide such as normal and mancozeb, with the generation of delaying drug resistance.The chemical structural formula of dimethomorph is as follows:
Boscalid (Boscalid), its chemical name, 2-chloro-N-(4 '-chlorodiphenyl-2-yl) vitamin PP; Structural formula is:
Boscalid is a kind of nicotinamide bactericide, by BASF Aktiengesellschaft, researched and developed first successfully, fungicidal spectrum is wider, there is prevention effect, almost all types of fungal diseases are had to activity, very effective to preventing and treating powdery mildew, gray mold, root rot, stalk break and various rots etc., be difficult for producing cross resistance, resistance bacterium to other medicaments is also effective, is mainly used in comprising the control of the diseases such as rape, grape, fruit tree, vegetables and field crop.Result of the test shows, Boscalid has obvious control efficiency to sclerotinia rot of colza, other medicaments that are better than applying at present.
Boscalid is a kind of mitochondrial respiratory inhibitor, for succinate dehydrogenase inhibitors (SDHI), it works by suppressing succinic acid ubiquinone reductase (also referred to as Complex II) on mitochondria electron transport chain, and its mechanism of action and other amide-types and benzamide series bactericidal agent are similar.It all has effect to the whole growth link of pathogen, and especially spore-germination inhibitory action is stronger.It also has outstanding preventive effect and good leaf intrinsic permeability.
Boscalid is blade face applying bactericidal agent, can, in the vertical infiltration of leaves of plants portion with to top transmission, have excellent prevention effect, and have certain result for the treatment of.It can suppress spore germination, germ tube elongation, hapteron formation, also effective in the every other vegetative period of fungi, presents remarkable resistance of rainwater washing against and lasting effect.
Boscalid is wide spectrum, systemic fungicide, and it can effectively prevent and treat the disease that sterol inhibitor, double imide class, benzimidazole, aniline pyrimidine class, phenylamide and methoxy acrylic bactericide is produced to resistance.This product can transfer to by xylem blade tip and the leaf margin of plant to top; It also has vertical osmosis, can organize by leaf portion, is delivered to the back side of leaf; But, this product is very little in vapor phase reallocation effect.Boscalid is mainly sprayed by cauline leaf, for preventing and treating powdery mildew, brown rot (Monilinia spp), the leaf spot (Mycosphaerella spp) on grape, lawn, fruit tree, vegetables and ornamental plants and the disease being caused by alternaric bacteria (Alternaria spp), botrytis cinerea (Botrytis spp), sclerotium germ (Sclerotinia spp).Also can farming thing for cereal, grape, peanut and potato etc. with complex preparation.
Summary of the invention
With regard to reducing rate of application and improving with regard to the activity profile of known compound Boscalid and dimethomorph, the object of this invention is to provide at the reactive compound reducing and use under total amount, harmful fungoid is had and improves active composition (Synergistic composition).
We find, meanwhile, i.e. and associating or separate administration Boscalid and dimethomorph, or use successively Boscalid and dimethomorph makes to prevent and treat better harmful fungoid than using separately each compound.
The invention provides a kind of Fungicidal composition, said composition is by carrying out binary built by Boscalid and dimethomorph, make the composition obtaining in control efficiency, there is gain effect, and expanded fungicidal spectrum, played the multiplex effect of a medicine, effectively slowed down or avoid germ to develop immunity to drugs.Astoundingly, the bactericidal activity of active compound combinations of the present invention is than active the adding with obviously higher of each reactive compound.In other words, there is synergistic effect unpredictable, necessary being, and be not only active augmenting.
When reactive compound is present in Fungicidal composition of the present invention with specific weight ratio, synergistic effect is obvious especially.But the weight ratio of the reactive compound in Fungicidal composition of the present invention can change within the specific limits.
A kind of Fungicidal composition of the present invention is to take following technical scheme to realize:
A kind of Fungicidal composition, is characterized in that: contain active component Boscalid and dimethomorph, wherein the percentage by weight of Boscalid and dimethomorph is 1:100-100:1, preferably 1:50-50:1, more preferably 1:25-25:1, more preferably 1:10-10:1.
Prevent and treat a method for plant pathogen, Fungicidal composition Boscalid and dimethomorph are acted on to pathogenic bacteria and/or its environment, or in plant, plant parts, seed, soil, region, material or space.
Prevent and treat a method for plant pathogen, Boscalid and dimethomorph are used simultaneously or used respectively or sequential application.
Prevent and treat a method for plant pathogen, Fungicidal composition Boscalid and dimethomorph are acted on to pathogenic bacteria and/or its environment, or in plant, plant parts, seed, soil, region, material or space.
A kind of Fungicidal composition, Boscalid and dimethomorph mix with filler and/or surfactant.
A kind of Fungicidal composition, can be mixed with the upper any formulation allowing of agricultural.The formulation of described Fungicidal composition is suspending agent, seed coat agent, wetting powder, water dispersible granules, microcapsule suspending agent, microcapsule suspension-suspending agent, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
The purposes of a kind of Fungicidal composition for preventing and treating fungi on cereal, fruit, vegetables.
Described Fungicidal composition is for preventing and treating the purposes of gray mold, downy mildew, late blight, early blight.
The purposes of described Fungicidal composition for preventing and treating fungi on cereal, fruit, vegetables.
Described Fungicidal composition is prevented and treated a large amount of fungies at various crop plants for example, as banana, cotton, vegetable variety (cucumber, beans, tomato and cucurbitaceous plant), barley, dogstail, oat, coffee, potato, corn, fruit variety, rice, rye, soybean, grape vine, wheat, ornamental plants, sugarcane and a large amount of seed in and is even more important.
Fungicidal composition of the present invention has extraordinary fungicide performance, and can be used to prevent and treat phytopathogenic fungi, as Plasmodiophoromycetes, Oomycete, Chytridiomycetes, connect with wide region plant pathogenic fungis such as Gammaproteobacteria, Ascomycetes, Basidiomycetes, deuteromycetes and there is excellent activity.Contain Boscalid and dimethomorph Fungicidal composition and can in crop protection, be used as blade face fungicide, as fungicide, be used for seed dressing and be used as soil fungicide.
Fungicidal composition of the present invention is particularly suited for preventing and treating following plant disease:
Chain lattice spore (AIternaria) on-vegetables, oilseed rape, sugar beet and fruit and rice belongs to,
Silk capsule mould (Aphanomyces) on-sugar beet and vegetables belongs to,
Bipolaris (Bipolaris) in-corn, Cereal, rice and lawn belongs to and interior navel is wriggled spore
(Drechslera) belong to,
Standing grain powdery mildew (Blumeria graminis) (powdery mildew) on-Cereal,
Botrytis cinerea (Botrytis cinerea) (gray mold) on-strawberry, vegetables, flowers and grape vine,
Lettuce dish stalk mould (Bremia lactucae) on-lettuce,
Tail spore (Cercospora) on corn, soybean, rice and sugar beet belongs to,
(for example the standing grain on Cereal revolves spore to cochliobolus (Cochliobolus) genus on-corn, Cereal, rice
Chamber bacterium (Cochliobolus sativus), the palace portion cochliobolus (Cochliobolus miyabeanus) on rice),
Thorn dish spore (Colletotricum) on-soybean and cotton belongs to,
Interior navel on-Cereal and corn wriggle spore (Drechslera) belong to,
Prominent navel on-corn wriggle spore (Exserohilum) belong to,
. two spore powdery mildews (Erysiphe cichoracearum) and monofilament shell powdery mildew on cucumber
(Sphaerotheca fuliginea) ,
Fusarium (Fusarium) on-each Plants belongs to and wheel branch spore (Verticillium) belongs to,
Gaeumannomyce (Gaeumanomyces graminis) on-Cereal belongs to,
Red mould (Gibberella) on-Cereal and rice belongs to the (for example gibberella fujikuroi (Gibberella on rice
fujikuroi)) ,
Gram’s staining complex (Grain staining complex) on-rice,
Length on-corn and rice wriggle spore (Helminthosporium) belong to,
Michrodochium nivale on-Cereal,
Ball chamber bacterium (Mycosphaerella) on-Cereal, banana and peanut belongs to,
Yam bean layer rest fungus (Phakopsora pachyrhizi) on-soybean and mountain horse sulphur layer rust mattress
(Phakopsara meibomiae) ,
Phomopsis (Phomopsis) on-soybean and sunflower belongs to,
Phytophthora infestans (Phytophthora infestans) on-potato and tomato,
The raw single shaft of grape mould (Plasmopara viticola) on-grape vine,
Apple mildew bacterium (Podosphaera leucotricha) on-apple,
Wheat-based maize ear rot bacterium (Pseudocercosporella herpotrichoides) on-Cereal,
False downy mildew (Pseudoperonospora) on-lupulus and cucurbit belongs to,
Handle rest fungus (Puccinia) on-Cereal and corn belongs to,
Nuclear cavity bacteria (Pyrenophora) on-Cereal belongs to,
Pyricularia oryzae (Pyricularia 0 η zae), Bamboo grass wood photovoltaicing leather bacteria (Corticium sasakii), broom on-rice
Stalk Cylindrocarpon (Sarocladium oryzae), sheath rot of rice plant (S.attenuatum), rice leaf are black
Powder bacterium (Entyloma oryzae),
Piricularia oryzae (Pyricularia grisea) on-lawn and Cereal,
-lawn, rice, corn, cotton, oilseed rape, sunflower, sugar beet, vegetables and other are planted
Corruption mould (Pythium) on thing belongs to,
-cotton, rice, potato, lawn, corn, oilseed rape, potato, sugar beet, vegetables and its
Rhizoctonia (Rhizoctonia) on his plant belongs to,
Sclerotinite (Sclerotinia) on-oilseed rape and sunflower belongs to,
Wheat septoria (Septoria tritici) on wheat and the many spore (Stagonospora of clever withered shell
nodorum) ,
Grape snag shell (Erysiphe) on-grape vine,
Setospaeria on-corn and lawn belongs to,
Silk axle smut (Sphacelotheca reilinia) on-corn,
Thielaviopsis sp (Thievaliopsis) on-soybean and cotton belongs to,
Tilletia foetida (Tilletia) on-Cereal belongs to,
Smut (Ustilago) on-Cereal, corn and sugar beet belongs to,
Black star bacterium (Venturia) on-apple and pears belongs to (scab).
Fungicidal composition of the present invention is particularly useful for preventing and treating gray mold, downy mildew, early blight, late blight, the powdery mildew of cereal, fruit, vegetables.
In addition, the present composition is applicable to prevent and treat harmful fungoid as Paecilomyces varioti for example, in material (timber, paper, paint dispersion, fiber or fabric) protection and in stored prod protection.
Fungicidal composition of the present invention also demonstrates has very strong incentive action to plant.Therefore, they are applicable to mobilize the inside of plant to defend to resist harmful microbe attack.
In this article, plant excitation (induction of resistance) compound can be understood to such material, and system of defense that can stimulating plant, makes when inoculating harmful fungoid afterwards, can demonstrate the significant resistance to these fungies when processed plant.
Therefore, Fungicidal composition of the present invention is used in and has carried out for protective plant in certain hour after the processing of mentioned pathogen attack.A period of time that this protection reaches is generally from 1 to 10 day that uses reactive compound processing to start to calculate, preferably 1 to 7 day.
Fungicidal composition of the present invention can be converted into conventional formulation, for example suspending agent, seed coat agent, wetting powder, water dispersible granules, microcapsule suspending agent, microcapsule suspension-suspending agent, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
A kind of Fungicidal composition of the present invention comprises Boscalid and dimethomorph reactive compound.In described Fungicidal composition, the reactive compound of Boscalid and dimethomorph mixes with filler and/or surfactant.
Described Fungicidal composition, wherein the content of the reactive compound of Boscalid and dimethomorph accounts for the 5%-90% of Fungicidal composition.
Described Fungicidal composition, wherein the content of the reactive compound of Boscalid and dimethomorph accounts for the 10%-80% of Fungicidal composition.
Described Fungicidal composition, wherein the content of the reactive compound of Boscalid and dimethomorph accounts for the 20%-60% of Fungicidal composition.
Boscalid is known by EP-A 545099.Can there is with different crystal modifications and hydrated form (referring to WO 03/29219 and WO 2004/72039) in Boscalid.
According to the present invention, term " filler " refers to can be combined with reactive compound or for example combine, so that it is easier to be administered to the natural or synthetic organic or inorganic compound of object (plant, crop or careless class).Therefore, described filler is preferably inertia, at least should be agricultural acceptable.Described filler can be solid or liquid.
In the present invention, operable nonactive medium can be both that solid can be also liquid, can be used as for example having of solid media material use: phyteral powdery type (for example particle of soybean meal, starch, grain dust, wood powder, bark powder, sawdust, walnut shell powder, wheat bran, cellulose powder, coconut husk, corncob and tobacco stem, extract residue after plant essence etc.), paper, sawdust, pulverize synthesized polymer body, clay class (such as kaolin, bentonite, acid china clay etc.), the talcum powder class of synthetic resin etc.Silica (for example diatomite, silica sand, mica, moisture silicic acid, calcium silicates), chemical fertilizer, the clay fertilizer of active carbon, natural mineral matter class (float stone, attapulgite and zeolite etc.), the inorganic mineral powder of firing diatomite, sand, plastics medium etc. (such as polyethylene, polypropylene, polyvinylidene chloride etc.), potassium chloride, calcium carbonate, calcium phosphate etc., ammonium sulfate, ammonium phosphate, urea, greening ammonium etc., these materials can be used separately or two or more is mixed.
Can be used as can selecting of liquid media materials'use in following material, for example water, alcohol type (for example methyl alcohol, ethanol, isopropyl alcohol, butanols, ethylene glycol etc.), ketone (for example acetone, methyl ethyl ketone, isobutyrone, cyclohexanone etc.), ethers (for example ether, dioxanes, methylcellulose, oxolane etc.), aliphatic hydrocarbon class (for example kerosene, mineral wet goods), aromatic hydrocarbons class (for example benzene, toluene, dimethylbenzene, solvent naphtha, Fluhyzon, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbon, chlorobenzene, Deng), halogenated hydrocarbon class, amide-type, sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, animal wet goods.
For making the emulsification of active ingredient compound, disperse, solubilization, and/or wetting can use surfactant for example can enumerate fatty alcohol-polyoxyethylene ether, polyoxyethylene alkylaryl ether, polyoxyethylene high-grade aliphatic ester, the phosphate of polyoxyethylene alcohol or phenol, the fatty acid ester of polyalcohol, alkane aromatic sulfonic acid, naphthalene sulfonic acids polymer, lignosulfonates, a dress copolymer of macromolecule comb shape, butyl naphthalene sulfonate, alkylaryl sulfonates, alkyl sodium sulfosuccinate, grease, fatty alcohol and ethylene oxide condensate, the polyacrylates such as alkyltaurate, protein hydrolysate.Suitable oligosaccharide thing or polymer, the combination of for example vinyl monomer based on independent, acrylic acid, EO and/or PO or itself and for example (polynary) alcohol or (polynary) amine.
For making active ingredient compound decentralized stabilization, adhering to and/or combination, can use the adjuvants such as such as xanthans, aluminium-magnesium silicate, gelatin, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid (as cephalin and lecithin) and synthetic phospholipid, bentonite, sodium lignin sulfonate.
The wherein optional spent glycol of antifreezing agent, propane diols, glycerine, sorbierite.As the deflocculant of suspension product, can use the such as adjuvant of naphthalene sulfonic acids polymer, polymeric phosphate etc.
As defoamer, can use silicone defoaming agent.
Operable colouring agent, for example inorganic pigment, as iron oxide, titanium oxide and Prussian blue; And organic pigment/dyestuff: alizarin dyes, azo dyes and metal phthalocyanine dyestuff; And trace element, for example molysite, manganese salt, boron salt, mantoquita, cobalt salt, molybdenum salt and zinc salt.
Optionally, also can comprise other annexing ingredient, for example protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent, stabilizing agent, screening agent.
Described preparation of the present invention can be mixed described reactive compound to prepare with conventional additives by known way.Described conventional additives is as conventional extender and solvent or thinner, emulsifier, dispersant and/or adhesive or fixative, wetting agent, waterproofing agent, if need, can also comprise drier and colouring agent, stabilizing agent, pigment, defoamer, preservative, thickener, water and other processing aid.
These compositions not only comprise and can be applicable to immediately pending object as spraying or dusting equipment by suitable equipment, but also be included in to be applied to, need the concentrated business composition that dilutes before object.
Of the present invention can also be co-administered with other active component containing Boscalid and dimethomorph active compound, for example, for expanding activity profile or preventing from forming resistance.Described other active component such as fungicide, bactericide, attractant, insecticide, miticide, nematocide, growth regulator, weed killer herbicide, safener, fertilizer or semiochemical etc.
Reactive compound Boscalid and dimethomorph can be used simultaneously, or use respectively, or sequential application, and order during separate administration is on the nothing impact conventionally of the result of control.
Fungicidal composition of the present invention can itself be used, and with its dosage form or type of service prepared therefrom, uses.By conventional methods it is used, for example water, spraying, atomizing, broadcast sowing, dust, and as processing the powder, dry mixing powder of dry seed, moist seed dressing, wet-mixing kind, slurries seed dressing, process seed solution, process seed water solube powder, process the water solube powder of earth, or by formation shell etc.
When using Fungicidal composition of the present invention or while containing Fungicidal composition of the present invention,
-while conventionally processing plant parts, the rate of application of reactive compound is generally 5 to 2000g/ha, is preferably 20-900 g/ha, especially 50-750 g/ha.
In seed treatment, the rate of application of reactive compound is 1-1000g/100kg seed, is preferably 5-500g/100kg seed;
-for soil treatment: the rate of application of reactive compound is generally 0.1-10000 g/ha, preferably 1-5000 g/ha.
Above-mentioned dosage is only general exemplary dose, and during actual using, those skilled in the art can, according to actual conditions and needs, especially adjust rate of application according to the seriousness of the character of pending plant or crop and germ.
A kind of method of preventing and treating plant pathogen by before or after plant seeding or before or after plant emerges to seed, plant or soil spraying or dusting separately or the composition of co-administered Boscalid and dimethomorph carry out.
A kind of Fungicidal composition of the present invention, comprises Boscalid and dimethomorph, has synergistic function, and the bactericidal activity of the Fungicidal composition of Boscalid of the present invention and dimethomorph is than active the adding with obviously higher of each reactive compound.In other words, there is synergistic effect unpredictable, necessary being, and be not only active augmenting.
When reactive compound is present in Fungicidal composition of the present invention with specific weight ratio, synergistic effect is obvious especially.
The good bactericidal property of Fungicidal composition of the present invention can illustrate by following examples.Although independent reactive compound activity aspect its bactericidal action a little less than, Fungicidal composition demonstrate exceed each self-applying simply add and activity.
The present invention compared with prior art has following beneficial effect:
The invention provides a kind of Fungicidal composition, said composition is by carrying out binary built by Boscalid and dimethomorph, make the Fungicidal composition obtaining in control efficiency, there is gain effect, can Synergistic, and expanded fungicidal spectrum, played the effect of a medicine multiple-effect, in addition, because Boscalid is different with the dimethomorph mechanism of action, therefore can improve protection effect, make germ be difficult for developing immunity to drugs.
Embodiment
In order better to explain, invention main points of the present invention provide several preferably embodiments below.
The combination of active principles of different agricultural chemicals is made to agricultural chemicals, is effectively and the efficiently mode of one of the upper resistance germ of current development novel pesticide and control agricultural.The agricultural chemicals of different cultivars shows three kinds of type of action: summation action, synergistic effect and antagonism after mixing conventionally.But be specially which kind of effect, unpredictable, only have by great many of experiments and just can know.Compound synergic is well filled a prescription, and owing to obviously having improved actual control efficiency, has reduced the usage amount of agricultural chemicals, thereby has delayed widely the drug-fast generation speed of germ, is the important means of integrated control disease.
Inventor is by a large amount of screening tests, the different proportionings of Boscalid and dimethomorph have been carried out to lot of experiments and effectiveness analysis, discovery is in certain ratio range, the Fungicidal composition obtaining has gain effect, and be not only the simple addition of two kinds of medicaments, specifically with following embodiment, describe.
Example of formulations
Embodiment 1:2% Boscalid+10% dimethomorph suspending agent
Boscalid 2%
Dimethomorph 10%
Methyl naphthalene sulfonate formaldehyde condensate 10%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%
Each components such as active component, dispersant, wetting agent and water are mixed according to the ratio of formula, after grinding and/or high speed shear, obtain 2% Boscalid+10% dimethomorph suspending agent.
Embodiment 2 20% Boscalid+4% dimethomorph wetting powders
Boscalid 20%
Dimethomorph 4%
Lauryl sodium sulfate 2%
Sodium lignin sulfonate 5%
White carbon 10%
Kaolin complements to 100%
Active component, various auxiliary agent and filler etc. are mixed in the ratio composition of formula, after ultra-fine pulverizer disintegrating, obtain 20% Boscalid+4% dimethomorph wetting powder.
Embodiment 3 0.2% Boscalid+20% dimethomorph aqueous emulsions
Boscalid 0.2%
Dimethomorph 20%
1-METHYLPYRROLIDONE 15%
Calcium dodecyl benzene sulfonate 5%
Agriculture breast 600# 5%
Water complements to 100%
Former medicine, solvent, emulsifier are added together, make to be dissolved into even oil phase; Water-soluble component and water mixing are made to water; Under high-speed stirred, oil phase is mixed with water, make 0.2% Boscalid+20% dimethomorph aqueous emulsion.
Embodiment 4 3.5% Boscalid+1.5% dimethomorph water dispersion granulas
Boscalid 3.5%
Dimethomorph 1.5%
Sodium lignin sulfonate 4%
Lauryl sodium sulfate 5%
Urea 5%
Kaolin complements to 100%
Active component, dispersant, wetting agent, disintegrant and filler are mixed in the ratio of formula, through air-flow crushing, become wetting powder, then add a certain amount of water mixing extruding to make material.After drying screening, obtain 3.5% Boscalid+1.5% dimethomorph water dispersion granula.
Embodiment 5 20% Boscalid+0.2% dimethomorph suspending agents
Boscalid 20%
Dimethomorph 0.2%
Methyl naphthalene sulfonate formaldehyde condensate 10%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%
Each components such as active component, dispersant, wetting agent and water are mixed in the ratio of formula, after grinding and/or high speed shear, obtain 20% Boscalid+0.2% dimethomorph suspending agent.
Embodiment 6 7.5% Boscalid+2.5% dimethomorph oil-suspending agents
Boscalid 7.5%
Dimethomorph 2.5%
Methyl naphthalene sulfonate formaldehyde condensate 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Soybean oil complements to 100%
Each components such as active component, dispersant, wetting agent and water are mixed in the ratio of formula, after grinding and/or high speed shear, obtain the outstanding oil float agent of 7.5% Boscalid+2.5% dimethomorph.
Embodiment 7 1% Boscalid+10% dimethomorph wetting powders
Boscalid 1%
Dimethomorph 10%
Lauryl sodium sulfate 10%
Sodium lignin sulfonate 5%
White carbon 10%
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 8 50% Boscalid+1% dimethomorph suspending agents
Boscalid 50%
Dimethomorph 1%
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium 10%
MODIFIED LIGNOSULPHONATE 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%
Above-mentioned each component is mixed in proportion, and through sand milling, be prepared into suspending agent.
Embodiment 9 30% Boscalid+20% dimethomorph aqueous emulsions
Oil phase:
Boscalid 30%
Dimethomorph 20%
Methyl oleate 38%
Polystyrene 3.7%
Water:
Xanthans 0.07%
The sodium salt 1% of the naphthalene sulfonic acids-formaldehyde condensation products of sulfonation
Bactericide 0.2%
Water complements to 100%
Boscalid and dimethomorph are dissolved in methyl oleate, add polystyrene to obtain oil phase; According to the component in formula, mix and obtain water; Under agitation add water to obtain aqueous emulsion oil phase.
Embodiment 10 25% Boscalid+1% dimethomorph wetting powders
Boscalid 25%
Dimethomorph 1%
Sodium lignin sulfonate 4%
NaLS 2%
The silicic acid 1% of high degree of dispersion
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 11 1% Boscalid+25% dimethomorph coated granules
Boscalid 1%
Dimethomorph 25%
Polyethylene glycol 3%
The silicic acid 1% of high degree of dispersion
Calcium carbonate complements to 100%
In blender, levigate active component is evenly applied on the carrier being soaked by polyethylene glycol.Can obtain in this way dustless coated granule.
Embodiment 12 20% Boscalid+70% dimethomorph wetting powders
Boscalid 20%
Dimethomorph 70%
Lauryl sodium sulfate 1%
Sodium lignin sulfonate 1%
White carbon 1%
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 13 20% Boscalid+60% dimethomorphs are extruded granule
Boscalid 20%
Dimethomorph 60%
Sodium lignin sulfonate 4%
Carboxymethyl cellulose 2%
Kaolin complements to 100%
Active component is mixed with auxiliary agent and grind, composition water-wet.Said composition is extruded, then dry in air stream.
Embodiment 14 1% Boscalid+50% dimethomorph suspending agents
Boscalid 1%
Dimethomorph 50%
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium 10%
MODIFIED LIGNOSULPHONATE 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%
Above-mentioned each component is mixed in proportion, and through sand milling, be prepared into suspending agent.
Embodiment 15 10% Boscalid+20% dimethomorph microcapsule suspension-suspending agents
Atlox 4913 4%
Citric acid 0.05%
Catalyzer 0.1%
Water 13%
Boscalid 10%
PAPI 1.35%
Solvesso 200 10%
Atlox4913 16%
Dispersant LFH 0.3%
Defoamer 0.16%
Urea 8.4%
Dimethomorph 20%
Water complements to 100%
By PAPI, the oil phase that Boscalid and Solvesso 100 form adds in the aqueous solution containing Atlox4913, forms emulsion.Then heat and be incubated 50
ounder C, add catalyst reaction 2 hours.After cooling, obtain the microcapsules of Boscalid.
Atlox 4913, dispersant LFH, defoamer, urea, dimethomorph and water mix in proportion, and through sand milling, are prepared into suspending agent.
The microcapsules of the Boscalid obtaining is added in the aqueous suspension agent of dimethomorph, stir and obtain 10% Boscalid+20% dimethomorph microcapsule suspension-suspending agent.
Embodiment 16 5% Boscalid+15% dimethomorph suspended emulsions
Boscalid 5%
Dimethomorph 15%
Solvesso 200 30%
Ethoxylated castor oil 4%
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium 10%
MODIFIED LIGNOSULPHONATE 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%
Boscalid is dissolved in Solvesso 200, adds ethoxylated castor oil, obtain the missible oil of Boscalid;
By dimethomorph, fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium, above-mentioned each component mixes in proportion, and through sand milling, is prepared into suspending agent.
Oil phase containing Boscalid is joined in the suspending agent containing dimethomorph, obtain suspended emulsion.
Embodiment 17 10% Boscalid+10% dimethomorph missible oil
Boscalid 10%
Dimethomorph 10%
Ethoxylated castor oil 5%
Calcium dodecyl benzene sulfonate 3%
Solvesso100 complements to 100%
Above-mentioned each component is mixed, be stirred to and obtain transparent homogeneous phase.
Embodiment 18 5% Boscalid+5% dimethomorph suspension seed-coating agents
Boscalid 5%
Dimethomorph 5%
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium 10%
MODIFIED LIGNOSULPHONATE 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
PVP-K30 1%
Water complements to 100%
Above-mentioned each component is mixed in proportion, and through sand milling, be prepared into suspension seed-coating agent.
Embodiment 19 40% Boscalid+60% dimethomorphs
Boscalid 40%
Dimethomorph 60%
Boscalid and dimethomorph are proportionally mixed.
Above embodiment proportioning is weight per distribution ratio.
The in vitro synergy test of biological test example is measured
According to the abundant method of Sun Yun, calculate the toxicity index of each medicament and the co-toxicity coefficient of mixture (CTC value), when CTC≤80, compositions table reveals antagonism, work as 80<CTC<120, compositions table reveals summation action, when CTC >=120, compositions table reveals synergistic effect.
Actual measurement toxicity index (ATI)=(standard medicament EC50/ reagent agent EC50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[theoretical toxicity index of mixture actual measurement toxicity index (ATI)/mixture (TTI) * 100
Test one: the toxicity test of grey mould fruit rot of strawberry
Be selected from three to the four leaf phase Strawberry Seedlings that growing way is consistent, each processing selects 3 basins for examination Strawberry Seedlings, uses potter spray tower at the spraying of 50PSI pressure column, the about 5mL of every basin.After chemicals treatment, 24h connects bacterium, the grey mould fruit rot of strawberry leaf that picks up from field is evenly shaken off to conidium above Strawberry Seedlings and inoculate, and then Strawberry Seedlings is put into greenhouse and cultivates.After 7d, according to the morbidity grade scale complete stool of grey mould fruit rot of strawberry, investigate disease index, and calculate control efficiency, then by method of least squares, calculate concentration EC in inhibition
50, then calculate co-toxicity coefficient (CTC) according to the abundant method of Sun Yun.
Table one: the virulence test result of control grey mould fruit rot of strawberry
From table one, Boscalid and dimethomorph are prevented and treated grey mould fruit rot of strawberry in the scope of 1:100-100:1, and co-toxicity coefficient is all greater than 120, illustrate that both all show as gain effect at the mixture within the scope of this, especially when both ratio is in 1:1, gain effect is particularly outstanding.
Test two: the toxicity test of target
Be selected from the potato set that growing way is consistent, each processing selects 3 basins for examination leaf seedling, uses potter spray tower in the spraying of 50PSI pressure column, the about 5mL of every basin, and each medicament arranges 12 concentration gradients.After chemicals treatment, 24h connects bacterium, the target leaf that picks up from field is evenly shaken off to conidium above potato set and inoculate, and then potato set is put into greenhouse and cultivates.After 7d, according to the morbidity grade scale complete stool of target, investigate disease index, and calculate control efficiency, then by method of least squares, calculate concentration EC in inhibition
50, then calculate co-toxicity coefficient (CTC) according to the abundant method of Sun Yun.
Table two: the virulence test result of preventing and treating target
From table two, Boscalid and dimethomorph are prevented and treated in target in the scope of 1:100-100:1, and co-toxicity coefficient is all greater than 120, illustrate that both all show as gain effect at the mixture within the scope of this, especially when both ratio is in 5:1, gain effect is particularly outstanding.
The Toxicity Determination of three pairs of downys mildew of garpe of test
Table three: the virulence test result of preventing and treating downy mildew of garpe
From table three, Boscalid and dimethomorph are prevented and treated downy mildew of garpe in the scope of 1:100-100:1, and co-toxicity coefficient is all greater than 120, illustrate that both all show as gain effect at the mixture within the scope of this, especially when both ratio is in 1:1, gain effect is particularly outstanding.
Efficiency test:
When the effect of active compound combinations exceedes the summation of the effect when each reactive compound is used separately, there is synergistic function.The predictive role of the particular combination of two kinds of reactive compounds can be used so-called " Colby formula " (referring to S.R. Colby, " Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) calculate as follows: if
X is the activity when using consumption for mg/ha or the concentration reactive compound A that is mppm;
Y is the activity when using consumption for ng/ha or the concentration reactive compound B that is nppm, is expressed as the percentage that accounts for untreated control;
E is the activity when using consumption for m and n g/ha or the concentration reactive compound A that is m and n ppm and B,
So
If the activity of actual observation (O) is greater than expection active (E), so said composition super add and, there is synergistic effect.
Following biological test example is in order to illustrate the present invention.But the present invention is not limited to these embodiment.
Test four: to the prolection of strawberry Botrytis cinerea (Botrytis cinerea) (grey mould fruit rot of strawberry)
The leaf of potted plant Strawberry Seedlings is sprayed with the aqueous suspension of the activity compound concentration with following appointment.Second day by the spore suspension of the plant inoculating grey mould fruit rot of strawberry of processing.Then basin is placed on to 20-22
oin the chamber with high atmospheric humidity (90-95%) under C 24 hours.During this period, spore-germination and germ tube infiltrate in leaf texture.Second day, test plants is back in greenhouse and at 20-22
0under C atmospheric humidity relative to 65-70%, cultivate other 7 days.Then estimate the degree of botrytis cinerea development on leaf.
Test five: to the prolection of potato late blight
Potted plant potato set is sprayed with the aqueous suspension of the activity compound concentration with following appointment.Second day by the spore suspension of the plant inoculating potato late blight of processing.Then basin is placed on to 20-22
oin the chamber with high atmospheric humidity (90-95%) under C 24 hours.During this period, spore-germination and germ tube infiltrate in leaf texture.Second day, test plants is back in greenhouse and at 20-22
0under C atmospheric humidity relative to 65-70%, cultivate other 7 days.Then estimate the degree of late blight development on leaf.
Test six: to the prolection of downy mildew of garpe
Potted plant grape seedlings is sprayed with the aqueous suspension of the activity compound concentration with following appointment.Second day by the spore suspension of the plant inoculating downy mildew of garpe of processing.Then basin is placed on to 20-22
oin the chamber with high atmospheric humidity (90-95%) under C 24 hours.During this period, spore-germination and germ tube infiltrate in leaf texture.Second day, test plants is back in greenhouse and at 20-22
0under C atmospheric humidity relative to 65-70%, cultivate other 7 days.Then estimate the degree of downy mildew development on leaf.
Illustrate that Boscalid and dimethomorph carry out binary built downy mildew of garpe is prevented and treated and had synergistic function.
Claims (15)
1. a Fungicidal composition, is characterized in that: contain active component Boscalid and dimethomorph, wherein the weight proportion of Boscalid and dimethomorph is 1:100-100:1.
2. Fungicidal composition according to claim 1, is characterized in that: the weight proportion of described Boscalid and dimethomorph is 1:50-50:1.
3. Fungicidal composition according to claim 1, is characterized in that: the weight proportion of described Boscalid and dimethomorph is 1:25-25:1.
4. Fungicidal composition according to claim 1, is characterized in that: the weight proportion of described Boscalid and dimethomorph is 1:10-10:1.
5. Fungicidal composition according to claim 1, is characterized in that: wherein the content of Boscalid and dimethomorph accounts for the 5%-90% of Fungicidal composition.
6. Fungicidal composition according to claim 1, is characterized in that: wherein the content of Boscalid and dimethomorph accounts for the 10%-80% of Fungicidal composition.
7. Fungicidal composition according to claim 1, is characterized in that: wherein the content of Boscalid and dimethomorph accounts for the 20%-60% of Fungicidal composition.
8. a Fungicidal composition, is characterized in that: the reactive compound described in claim 1 is mixed with filler and/or surfactant.
9. Fungicidal composition according to claim 1, is characterized in that: described Fungicidal composition can be mixed with the upper any formulation allowing of agricultural.
10. Fungicidal composition according to claim 1, is characterized in that: described Fungicidal composition formulation is suspending agent, seed coat agent, wetting powder, water dispersible granules, microcapsule suspending agent, microcapsule suspension-suspending agent, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet, ultra low volume liquids.
Prevent and treat the method for plant pathogen, it is characterized in that for 11. 1 kinds: the Fungicidal composition in claim 1 is acted on to pathogenic bacteria and/or its environment, or in plant, plant parts, seed, soil, region, material or space.
12. methods according to claim 11, is characterized in that: Boscalid and dimethomorph are used simultaneously or used respectively or sequential application.
The purposes of 13. Fungicidal compositions claimed in claim 1 for preventing and treating fungi.
14. Fungicidal compositions claimed in claim 1 are for preventing and treating the purposes of gray mold, downy mildew, late blight, early blight.
The purposes of 15. Fungicidal compositions claimed in claim 1 for preventing and treating fungi on cereal, fruit, vegetables.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310724597.XA CN103719109A (en) | 2013-12-25 | 2013-12-25 | Fungicidal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310724597.XA CN103719109A (en) | 2013-12-25 | 2013-12-25 | Fungicidal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103719109A true CN103719109A (en) | 2014-04-16 |
Family
ID=50443605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310724597.XA Pending CN103719109A (en) | 2013-12-25 | 2013-12-25 | Fungicidal composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103719109A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107889833A (en) * | 2017-11-30 | 2018-04-10 | 天峨县平昌生态农业有限公司 | Prevent and treat the pharmaceutical composition and its application process of sugar cane cottony aphid |
| GB2562083A (en) * | 2017-05-04 | 2018-11-07 | Rotam Agrochem Int Co Ltd | Fungicidal composition and use thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282213A (en) * | 1997-12-18 | 2001-01-31 | 巴斯福股份公司 | Fungicide mixtures based on carboxamides and morpholine or pyridine derivatives |
| CN102316729A (en) * | 2009-02-11 | 2012-01-11 | 巴斯夫欧洲公司 | Dimethomorph as safener for pesticides with phytotoxic effects |
| CN103518743A (en) * | 2013-10-12 | 2014-01-22 | 京博农化科技股份有限公司 | Sterilizing composition containing boscalid and dimethomorph |
| CN103636616A (en) * | 2013-11-19 | 2014-03-19 | 广西田园生化股份有限公司 | Ultra-low volume liquid containing boscalid and morpholine bactericide |
-
2013
- 2013-12-25 CN CN201310724597.XA patent/CN103719109A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282213A (en) * | 1997-12-18 | 2001-01-31 | 巴斯福股份公司 | Fungicide mixtures based on carboxamides and morpholine or pyridine derivatives |
| CN102316729A (en) * | 2009-02-11 | 2012-01-11 | 巴斯夫欧洲公司 | Dimethomorph as safener for pesticides with phytotoxic effects |
| CN103518743A (en) * | 2013-10-12 | 2014-01-22 | 京博农化科技股份有限公司 | Sterilizing composition containing boscalid and dimethomorph |
| CN103636616A (en) * | 2013-11-19 | 2014-03-19 | 广西田园生化股份有限公司 | Ultra-low volume liquid containing boscalid and morpholine bactericide |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2562083A (en) * | 2017-05-04 | 2018-11-07 | Rotam Agrochem Int Co Ltd | Fungicidal composition and use thereof |
| GB2562083B (en) * | 2017-05-04 | 2021-10-27 | Rotam Agrochem Int Co Ltd | Fungicidal composition and use thereof |
| CN107889833A (en) * | 2017-11-30 | 2018-04-10 | 天峨县平昌生态农业有限公司 | Prevent and treat the pharmaceutical composition and its application process of sugar cane cottony aphid |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103988845B (en) | A kind of Fungicidai mixtures | |
| CN104604938A (en) | Fungicidal composition and the use thereof | |
| CN102669181B (en) | Sterilization composition containing captan and copper calcium sulfate and application of sterilization composition | |
| CN103348989B (en) | A kind of Fungicidal mixture | |
| CN103348982B (en) | A kind of Fungicidal mixture | |
| CN105475357B (en) | A kind of bactericidal composition | |
| CN103392715B (en) | A kind of bactericidal composition containing cyprodinil and captan | |
| CN106922703A (en) | A kind of bactericidal composition | |
| CN103329937B (en) | Composition of bactericidal active components | |
| CN103348991A (en) | Fungicide composition containing boscalid and mancozeb | |
| CN103719109A (en) | Fungicidal composition | |
| CN103719125A (en) | Bactericide composition and application thereof | |
| CN103392739B (en) | Sterilizing composition containing mandipropamid and copper calcium sulphate | |
| CN103348990B (en) | Bactericidal composition containing mandipropamid and captan | |
| CN102986710A (en) | Bactericidal composition containing bellkute and difenoconazole and application of composition | |
| CN103999870A (en) | Fungicidal composition | |
| CN106922704A (en) | A kind of bactericidal composition | |
| CN103988843A (en) | Fungicidal composition | |
| CN106922722A (en) | A kind of bactericidal composition | |
| CN105076155A (en) | Plant disease preventing and treating composition | |
| CN105076192A (en) | Bactericidal mixture | |
| CN103988846B (en) | A kind of bactericidal composition | |
| CN105076161B (en) | A kind of bactericidal composition | |
| CN105076178B (en) | A kind of bactericidal composition | |
| CN105265456B (en) | A kind of bactericidal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140416 |