CN106922720A - A kind of bactericidal composition - Google Patents
A kind of bactericidal composition Download PDFInfo
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- CN106922720A CN106922720A CN201511008839.0A CN201511008839A CN106922720A CN 106922720 A CN106922720 A CN 106922720A CN 201511008839 A CN201511008839 A CN 201511008839A CN 106922720 A CN106922720 A CN 106922720A
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- prochloraz
- plant
- picarbutrazox
- bactericidal composition
- bacterium
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
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Abstract
The invention provides a kind of bactericidal composition, the microbicide compositions include active component Picarbutrazox and Prochloraz, and the weight ratio of Picarbutrazox and Prochloraz is 10:1-1:50.The present invention carries out binary built by by Picarbutrazox and Prochloraz so that the present invention has obvious gain effect on preventing and treating crop by fungi, bacterial disease；In addition fungicidal spectrum is also expanded by binary built, reduces respective usage amount, reduce the risk that germ develops immunity to drugs.
Description
Technical field
The present invention relates to a kind of bactericidal composition, plant, crop or seed are more particularly, to protected from fungal disease
Bactericidal composition.
Background technology
The current disease control for being agriculturally also easy to produce resistance, mixture is carried out using the different pesticide species of the mechanism of action
It is optimal selection, if reasonable mixture ratio, significant synergistic effect can be produced, field control effect is substantially better than each list
The effect of agent.Bactericide containing single-activity composition is usually present certain defect, continuous several times in agricultural disease preventing and treating
Using not only making pathogen be also easy to produce the resistance to the action of a drug, and easily cause the pollution to food and environment, by fungicidal activity into point it
Between rational mixture can overcome disadvantage mentioned above.Rational compounding makes the synergistic effect that active ingredient is produced, and can improve preventive effect, subtracts
Few effective ingredient consumption, it is cost-effective, delay the drug-fast generation of pathogen, and then can mitigate or even avoid agricultural chemicals to food
The pollution of thing and environment.
On pesticide activity, particularly to crop protection, one of key problem of research carried out in the technical field is
Improve the performance in terms of performance, especially bioactivity and the performance for keeping within a certain period of time in terms of this activity.
Picarbutrazox, test code number NF-171；CAS：500207-04-5；Chemical formula for [6- [[[[(z)-(1- methyl-
1H-TETRAZOLE -5- bases)（Phenyl）Methylene] amino] epoxide] methyl] pyridine -2- bases] t-butyl carbamate；Molecular structural formula
For：
Picarbutrazox is the oximino ether bactericide of Japanese Cao Da companies exploitation, and it has preferable to downy mildew and epidemic disease
Prevention effect.Picarbutrazox is by known in CN02817805.X.
Prochloraz（Prochloraz）, its chemical name is：N- propyl group-N- [2- (2,4,6- Trichlorophenoxies) ethyl]-
Imidazoles -1- formamides, are imidazoles wide-spectrum bactericides, and its structural formula is：
Prochloraz is worked by suppressing the biosynthesis of sterol, without systemic action, is caused for sac fungus and Fungi Imperfecti
Multiple diseases preventive effect is splendid.Prochloraz uses gene inductive technology, and activated plant disease-resistant gene expression, quick-acting is good, the lasting period
It is long.Prochloraz can be used to preventing and treating gourd, fruit and vegetable anthracnose, leaf spot, bakanae disease of rice, rice blast citrus anthracnose, blossom-end rot,
Penicilliosis, green mould, banana anthracnose, leaf spot；The vegetables such as mango anthracnose, leaf spot of peanut, capsicum, eggplant, muskmelon, tomato
Dish anthracnose, Strawberry anthracnose, sclerotinia rot of colza, leaf spot, mushroom brown spot, apple anthracnose, pear scab etc..Prochloraz
To there is treatment and eradicant action to the multiple diseases on field crop, fruit and vegetable, turf and ornamental plant.
Because the environmental requirement and economic requirement now to bactericide are constantly improve, such as to activity profile, toxicity, selection
The requirement of property, rate of application, residual and favourable preparation feasibility, additionally asks due to being there may be in terms of such as drug resistance
Topic, therefore, exploitation is in some aspects lasting task better than the new bactericide of existing bactericide.
The content of the invention
It is an object of the invention to provide a kind of bactericidal composition, just reduced in the case where the reactive compound for reducing is using total amount and applied
For activity profile with rate and improvement known compound Picarbutrazox and Prochloraz, the present invention is reducing reactive compound
Under using total amount, having to harmful fungoid improves activity（Synergistic）.
We have found that simultaneously, i.e., jointly or separately applying Picarbutrazox and Prochloraz, or apply successively
Picarbutrazox and Prochloraz cause preferably to prevent and treat harmful fungoid than each compound is administered alone.
The invention provides a kind of bactericidal composition, said composition carries out two by by Picarbutrazox and Prochloraz
Unit's compounding so that the mixture for obtaining has gain effect in prevention effect, and has expanded fungicidal spectrum, serves a medicine many
Effect, effectively slows down or avoids germ to develop immunity to drugs.Astoundingly, the bactericidal activity of bactericidal composition of the invention
It is more active plus and considerably higher than each reactive compound.In other words, there is unpredictable, necessary being collaboration effect
Should, and it is not only the supplement of activity.
When reactive compound is present in bactericidal composition of the invention with specific weight ratio, cooperative effect is especially bright
It is aobvious.But, the weight ratio of the reactive compound in bactericidal composition of the present invention can change within the specific limits.
Can have greater activity and the more long bactericidal composition of activity holding the invention provides a kind of.This sterilized group
Compound has relatively low-dose, while the toxicity of the bactericidal composition is relatively low, fruits and vegetables and seed with fungal disease is carried out
Control.
A kind of bactericidal composition of the present invention is to take following technical scheme to realize：
A kind of bactericidal composition, it is characterised in that：Containing active component Picarbutrazox and Prochloraz, wherein
The percentage by weight of Picarbutrazox and Prochloraz is 10:1-1:50, preferably 10:1-1:40, more preferably 10:
1-1:30, it is further preferably 1:1-1:25, it is further preferably 1:1-1:20, more preferably 1:1-1:15, more preferably 1:1-1:10,
More preferably 1:1-1:5.
The weight proportion of Picarbutrazox and Prochloraz in the present invention for example can also be 10:1、5:1、1:1、1:
5、1:10、1:15、1:20、1:25、1:30、1:35、1:40、1:45、1:50。
Described bactericidal composition, it is characterised in that：The Picarbutrazox and Prochloraz quality sum account for described killing
The 5%-90% of bacteria composition quality, more preferably 10%-80%, more preferably 20%-60%.
Described Prochloraz includes Prochloraz metal salt compound.Wherein metal is selected from the first to the second mistake in the periodic table of elements
Race's element is crossed, especially manganese, iron, zinc, copper；Also the second Main Group Metal Elements, from calcium or magnesium；And the third and fourth race master
Race's metallic element, especially aluminium or tin.
The Prochloraz metal salt compound is selected from prochloraz-manganese chloride complex, zinc salt, molysite, calcium salt, mantoquita, magnesium salts, aluminium salt
And pink salt.It is preferred that prochloraz-manganese chloride complex.
A kind of method for preventing and treating plant pathogen, pathogenic bacteria and/or its environment, Huo Zhezhi are acted on by bactericidal composition
In thing, plant parts, seed, soil, region, material or space.
It is a kind of prevent and treat plant pathogen method, by Picarbutrazox and Prochloraz be administered simultaneously or apply respectively,
Or sequential application.
A kind of bactericidal composition, comprising Picarbutrazox and Prochloraz and filler and/or surfactant.
A kind of bactericidal composition, can be configured to any formulation for agriculturally allowing.The formulation of described bactericidal composition is
It is suspending agent, seed coat agent, wettable powder, water dispersible granules, microcapsule suspending agent, coated granule, extrusion granule, missible oil, micro-
Emulsion, aqueous emulsion, effervescent tablet, ultra low volume liquids.
Described bactericidal composition is used to prevent and treat cereal, vegetables, clover, soybean, turf, timber, trees, fruit tree or gardening
The purposes of fungi and bacterium on plant.
The bactericidal composition is used to protect the purposes of plant propagation material and the plant organ for then growing.
The bactericidal composition is used to prevent and treat the purposes of fruit vegetables storing period disease.
The bactericidal composition be applied to needed for preventing and treating place preventing and treating soil cause a disease or saprophytic fungi and bacterium use
On the way.
Described bactericidal composition is in various crop plants such as banana, cotton, vegetable variety（Such as cucumber, beans, tomato
And cucurbitaceous plant）, it is barley, dogstail, oat, coffee, potato, corn, fruit variety, rice, rye, soybean, grapevine, small
A large amount of fungies are prevented and treated in wheat, ornamental plant, sugarcane and a large amount of seeds to be even more important.
A kind of plant pathogenic fungi of control plant, plant part, plant propagation material and the plant organ for then growing
Method, including by the amount of application of bactericidal composition of the invention effective and basic plant-less toxicity with agronomy with Seed Treatment,
The methods such as foliage applying, stem are applied, are impregnated with, instiling, pouring into a mould, spraying, spraying, dusting, distribution or smoke are administered to plant, plant
Partly, during plant propagation material or plant are growing or are needing the soil that grows wherein or cultivation medium.
Bactericidal composition of the invention has very strong activity to various phytopathogens, and can be to being drawn by phytopathogen
The prevention and treatment of the plant disease for rising play very strong preventive effect.Bactericidal composition of the invention to such as Plasmodiophoromycetes,
Oomycete, Chytridiomycetes, connect there is pole with the wide scope plant pathogenic fungi such as Gammaproteobacteria, Ascomycetes, Basidiomycetes, deuteromycetes
Good activity.
Bactericidal composition of the invention also has extraordinary bactericidal performance, and it is thin to can be used for preventing and treating plant pathogenic
Bacterium.Such as pseudomonadaceae, Rhizobiaceae, enterobacteriaceae, bar Cordycepps and Streptomycetaceae.
Bactericidal composition of the invention can be used as blade face fungicide in crop protection, can act also as fungicide use
In seed dressing and as soil fungicide.
Bactericidal composite of the invention also can be used to prevent and treat the disease of fruit vegetables storing period.
Bactericidal composition of the invention is particularly suitable for the following phytopathogen of preventing and treating：
As oomycetes subclass, can be exemplified as, such as various crops such as the corruption of black leg of beet bacterium (Pythium ultium)
Mould category bacterium；Such as potato blight bacterium (PhytophthoraiNfestaNs), botrytis cinerea (Phytophthora
Capsici Phytophthora category bacterium)；Such as bacterium of downy mildew of cucumber (PseudoperoNospora cubeNsis), Humulus
The Pseudoperonospora bacterium of Pseudoperonospora cubensis (PseudoperoNospora humuli)；Such as Plasmopara viticola (Plasmopara
Viticola Plasmopara bacterium)；Such as Pseudoperonospora cubensis (PeroNospora brassicae), the green onion downy mildew of brassicaceous vegetable
Germ (PeroNospora destructor), Peronospora bacterium of downy mildew of spinach bacterium (PeroNospora spiNaciae) etc..
As Ascomycetes, can be exemplified as, for example, such as the powdery mildew of powdery mildew of cereals bacterium (ErysiphegramiNis)
Category bacterium；Such as the Sphaerotheca bacterium of greengrocery powdery mildew (Sphaerotheca fuligiNea)；Such as apple black star bacteria
The Venturia bacterium of (VeNturia iNaequalis), pear cucumerinum (VeNturia Nashicola)；Such as net blotch of barley
The PyreNophora category bacterium of bacterium (PyreNophorateres)；Such as wheat class spot disease (Cochliobolus sativus)
Cochliobolus belongs to bacterium；Such as Sclerotinia bacterium of greengrocery hyphal cluster germ (SclerotiNia sclerotiorum).
As Basidiomycetes, can be exemplified as, for example, such as double spores of wheat leaf rust germ (PucciNiarecoNdita)
Rust bacterium；Such as the Tilletia bacterium of bunt of wheat bacterium (Tilletia caries)；Such as loose smut of barley bacterium
The Ustilago bacterium of (Ustilago Nuda) etc.
As Deuteromycotina, can be exemplified as, for example, such as the Phoma of lucid asparagus Phoma asparagi Sacc (Phomaasparagi)
Bacterium；Such as the Septoria bacterium of wheat class crust rot bacterium (Septoria Nodorum)；Such as Colletotrichumlagenarium
The Colletotrichum bacterium of (Colletotrichum lageNarium)；Such as wilt (Pyricularia oryzae)
Pyricularia belongs to bacterium；Such as the Botrytis bacterium of greengrocery ash arrhizus bacteria (Botrytis ciNerea)；Such as apple spot fallen leaves
Germ (AlterNaria mali), the Alternaria bacterium of tomato early blight bacterium (AlterNaria solaNi)；Such as beet Cercospora
The Cercospora bacterium of germ (Cercospora beticola)；Such as peach black star germ (Cladosporium carpophilum)
Blastocladia bacterium；Such as Rhizoctonia bacterium of Oryza sheath blight fungus (RhizoctoNia solaNi).
Suitable crop mainly includes field crop, such as corn, soybean, cotton, rape oilseeds, such as southern general rape
(Brassica napus) (such as rape (canola)), overgrown with weeds green grass or young crops (Brassica rapa), leaf mustard (B.juncea) (such as mustard
Sub (mustard)) and brassicacarinata (Brassica carinata), rice, wheat, beet, sugarcane, oat, brown wheat, greatly
Wheat, broomcorn millet, triticale, flax, grapevine and the other fruit of various plants or vegetable crop, such as rose family (Rosaceaesp.)
(for example, pip fruit, such as apple and pears, also drupe, such as apricot, cherry, almond and peach, berry such as strawberry), tea sugarcane
Scarabaeidae (Ribesioidae sp.), Juglandaceae (Juglandaceae sp.), Betulaceae (Betulaceae sp.), Anacardiaceae
(Anacardiaceae sp.), Fagaceae (Fagaceae sp.), Moraceae (Moraceae sp.), Oleaceae (Oleaceae
Sp.), Actinidiaceae (Actinidaceae sp.), Lauraceae (Lauraceae sp.), Musaceae (Musaceae sp.) be (for example
Banana tree and powder bajiao banana (plantings)), Rubiaceae (Rubiaceae sp.) (such as coffee), Theaceae (Theaceae
Sp.), Sterculiaceae (Sterculiceaesp.), Rutaceae (Rutaceae sp.) (such as lemon, orange and grape fruit)；Solanaceae
(Solanaceaesp.) (for example, tomato, potato, pepper, eggplant), Liliaceae (Liliaceae sp.), composite family
(Compositiae sp.) (such as lettuce, globe artichoke and witloof-include root witloof (root chicory), hare's-lettuce (endive)
Or common witloof (common chicory)), Umbelliferae (Umbelliferae sp.) (such as carrot, parsley, celery and block
Rooted celery), Curcurbitaceae (Cucurbitaceae sp.) (for example cucumber-include pickled cucumber (pickling cucumber), south
Melon, watermelon, cucurbit and muskmelon), green onion section (Alliaceae sp.) (such as onion and leek), Cruciferae (Cruciferae
Sp.) (for example white cabbage, red cabbage, broccoli, cauliflower, brussels sprout, green vegetables, kohlrabi, radish, horseradish, solely
Row dish, Chinese cabbage), pulse family (Leguminosaesp.) (such as peanut, pea and French beans-such as climning bean and broad bean), Chenopodiaceae
(Chenopodiaceae sp.) (such as fodder beet, spinach sweet (spinach beet), spinach, beet root), Malvaceae
(Malvaceae) (such as gumbo), Asparagaceae (Asparagaceae) (such as lucid asparagus)；Garden crop and forest crop；
Ornamental plant；And the homologue of the genetic modification of these crops.
The preferably for example following disease of Bactericidal composite of the invention etc. is prevented and kill off：
The brown spot (Cercospora beticola) of " beet ", black root（Aphanomyces cochlloides）, root-rot
Disease（Thanatephorus cucumeris）, leaf rot（Thanatephorus cucumeris）；
The brown spot of " peanut "（Mycosphaerella arachidis）, black spot（Mycosphaerella
berkeleyi）；
The powdery mildew of " cucumber "（Sphaerotheca fuliginea）, downy mildew（Pseudoperonospora
cubensis）, blight dis-ease（Mycosphaerella melonis）, dead arm（Fusarium oxysporum）, sclerotiniose
（Sclerotinia sclerotiorum）, gray mold（Botrytis cinerea）, anthracnose（Colletotrichum
orbiculare）, scab（Cladosporium cucumerinum）, brown spot（Corynespora cassicola）, seedling
Damping-off（Pythium debaryanam, Rhizoctonia solani Kuhn）, bacterial leaf spot（Pseudomonas
syringae pv.Lecrymans）；
The gray mold of " tomato "（Botrytis cinerea）, leaf mold（Cladosporium fulvum）, late blight
（Phytophthora infestans）；
The gray mold of " eggplant "（Botrytis cinerea）, bacterial blight（Corynespora melongenae）, powdery mildew
（Erysiphe cichoracearum）, suede bacterial plaque disease（Mycovellosiella nattrassii）；
The gray mold of " strawberry "（Botrytis cinerea）, powdery mildew（Sohaerotheca humuli）, anthracnose
（Colletotrichum acutatum、Colletotrichum fragariae）, epidemic disease（Phytophthora
cactorum）；
The neck rot of " onion "（Botrytis allii）, gray mold（Botrytis cinerea）, hickie leaf blight
（Botrytis squamosa）, downy mildew（Peronospora destructor）；
The root knot of " cabbage "（Plasmodiophora brassicae）, soft rot（Erwinia carotovora）, frost
Mildew（Peronospora parasitica）；
The sclerotiniose of " French beans "（Sclerotinia sclerotiorum）, gray mold（Botrytis cinerea）；
The powdery mildew of " apple "（Podosphaera leucotricha）, scab（Venturia inaequalis）, spend corruption
Disease（Monilinia mali）, diplostomiasis（Mycosphaerella pomi）, rot（Valsa mali）, spot defoliation
（Alternaria mali）, rust（Gymnosporangium yamadae）, ring spot（Botryosphaeria
berengeriana）, anthracnose（Glomerella cingulata、Colletotrichum acutatum）, brown spot
（Diplocarpon mali）, fly pinta（Zygophiala jamaicensis）, sooty mould（Gloeodes pomigena）；
The powdery mildew of " persimmon "（Phyllactinia kakicola）, anthracnose（Gloeosporium kaki）, angle spot fallen leaves
Disease（Cercospora kaki）；
The brown rot of " peach "（Monilinia fructicola）, scab（Cladosporium carpophilum）, intend stem
Point mildew（Phomopsis sp.）；
The brown rot of " cherry "（Monilinia fructicola）；
The gray mold of " grape "（Botrytis cinerea）, powdery mildew（Uncinula necator）, late blight
（Glomerella cingulata、Colletotrichum acutatum）, downy mildew（Plasmopara viticola）, it is black
Acne disease（Elsinoe ampelina）, brown spot（Pseudocercospora vitis）, black rot（Guignardia
bidwellii）；
The scab of " pears "（Venturia nashicola）, rust（Gymnosporangium asiaticum）, black spot
（Alternaria kikuchiana）, ring spot（Botryosphaeria berengeriana）, powdery mildew
（Phyllactinia mali）；
The zonate spot of " tea "（Pestalotia theae）, anthracnose（Colletotrichum theae-sinensis）；
The shot hole of " citrus "（Elsinoe fawcetti）, penicilliosis（Penicillium italicum）, green mould
（Penicillium digitatum）, gray mold（Botrytis cinerea）, diplostomiasis（Diaporthe citri）, ulcer
Disease（Xanthomonas campestris pv.Citri）；
The powdery mildew of " wheat "（Erysiphe graminis f.sp.tritici）, head blight（Gibberella zeae）, leaf
Rust（Puccinia recondita）, brown snow mold（Pythium iwayamai）, snow red rot
（Monographella nivalis）, wheat basal stem rot（Pseudocercosporella herpotrichoides）, leaf it is withered
Disease（Septoria tritici）, glume blight（Leptosphaeria nodorum）, the rotten sclerotium oryzicola of snow（Typhula
incarnata）, snow big grain sclerotinia rot（Myriosclerotinia borealis）, damping-off（Gaeumanomyces
graminis）；
The stripe disease of " barley "（Pyrenophora graminea）, clouding disease（Rhynchosporium secalis）, dissipate it is black
Fringe disease（Ustilago tritici、U.nuda）；
The rice blast of " rice "（Pyricularia oryzae）, banded sclerotial blight（Rhizoctonia solani）, bakanae disease
（Gibberella fujikuroi）, flax leaf spot（Cochliobolus niyabeanus）, seedling blight（Pythium
graminicola）, bacterial leaf-blight（Xanthomonas oryzae）, bacillary seedling blight（Burkholderia
plantarii）, brown streak（Acidovorax avenae）, the withered phytosis of paddy（Burkholderia glumae）
The sclerotiniose of " tobacco "（Sclerotinia sclerotiorum）, powdery mildew（Erysiphe cichoracearum）；
The gray mold of " tulip "（Botrytis cinerea）；
The snow big grain sclerotinia rot of " Western Korea lawn grass "（Sclerotinia borealis）, samping off（Pythium
aphanidermatum）；
The powdery mildew of " orchard grass "（Erysiphe graminis）；
The purple spot of " soybean "（Cercospora kikuchii）, downy mildew（Peronospora Manshurica）, cane blight
（Phytophthora sojae）；
Potato, tomato late blight（Phytophthora infestans）.
Bactericidal composition of the invention can be good preventing and treating cause pathogen and the medicament drug-fast bacteria of following disease：Paddy rice
Seedbed damping-off, bakanae disease；Disease in cotton seedling stage such as damping-off, anthracnose, samping off, red rot；Vegetable nursery bed disease is for example sudden
Sick anthracnose, damping-off, the phytophthora root rot of tomato, gray mold, leaf rust, spot disease, anthracnose and early phytophthora root rot；The frost of cucumber
Mildew, powdery mildew, gray mold, anthracnose, withered rattan disease, black spot and brown spot；The anthracnose and gray mold of strawberry；Pumpkin it is white
Powder disease, anthracnose and withered rattan disease；The hickie leaf blight of onion, black spot, gray mold and Mild Powder；The powdery mildew of eggplant, grey mold
Disease and bacterial blight；The black spot of shallot；The Leucoplakia and black spot of Chinese cabbage；The sclerotiniose and gray mold of green pepper；Cucumber it is white
Powder disease, anthracnose and withered rattan disease；The powdery mildew of muskmelon, anthracnose and withered rattan disease；The gray mold of lettuce；The black spot and ash of red bayberry
Mildew；The powdery mildew of persimmon, anthracnose, gray mold and defoliation；The gray mold of oranges and tangerines；The scab of pears, black spot and early epidemic
Mildew；The gray mold of grape, anthracnose, brown spot, black rattan are sick, withered rattan is sick, viscous rot and the swollen disease of branch；The scab of peach, ash
Pinta, anthracnose；The scab of apple, zonate spot, early phytophthora root rot, brown spot, coal point disease, coal spot disease, diplostomiasis and brown rot；
The stem wilt of mung bean, anthracnose, gray mold and sclerotiniose；The anthracnose of Kidney bean, gray mold and sclerotiniose；The ring spot of broad bean；
Purple spot of soybean；The powdery mildew of tobacco, the brown spot of beet and spot disease；The anthracnose of tea, zonate spot and the withered disease of sprouting and
Gray mold；Spend the plant diseases such as scab, anthracnose, gray mold and the powdery mildew of class.Bactericidal composition of the invention is particularly
Preventing and treating tomato that can be good, cucumber, eggplant, strawberry, grape, the epidemic disease of peach and oranges and tangerines, powdery mildew and the gray mold cause of disease
Phytopathogen and medicament drug-fast bacteria.
Bactericidal composition of the invention is especially suitable for preventing and treating apple, banana, grape, oranges and tangerines, mango, paddy rice, wheat, jade
Downy mildew on rice, potato, soybean, tomato, capsicum, cucumber, eggplant, grape, early blight, late blight, balck shank, scab,
Leaf spot, anthracnose, powdery mildew, wilt disease, damping-off, samping off.
The crop of bactericidal composition treatment of the invention is such as but not limited to cereal, vegetables, clover, soybean, turf, wood
Material, trees, fruit tree or gardening plant.
Fungicidai mixtures of the invention can also be used to prevent and treat fruit vegetables storing period disease.The fruit for for example being caused by following pathogen
It is real to rot：
Aspergillus bacterium, such as aspergillus flavus；
Botrytis（Botrytis）Strain, such as Botrytis cinerea（Botrytis cinerea）;
Penicillium（Penicillium）Strain, such as penicillium expansum（Penicillium expansum）With
P.purpurogenum;
Sclerotinia（Sclerotinia）Strain, such as sclerotinite（ Sclerotinia sclerotiorum）;
Verticillium（Verticilium）Strain, such as black and white wheel branch spore（Verticilium alboatrum）.
Bactericidal composition of the invention be also particularly well suited for preventing and treating fruit vegetables storing period disease blossom-end rot, green mould, penicilliosis,
Anthracnose.
Fungicidai mixtures of the invention can be additionally used in preventing and treating kind and pass and soil-borne disease.The kind for for example being caused by following pathogen
Pass and native rotten and wilting disease and the seedling disease for passing：
Alternaria category kind, such as rape give birth to rod method (Alternaria brassicicola);
Aphanomyces (Aphanomyce) category kind, such as mould (Aphanomyces of Kidney bean silk capsule
euteiches) ;
Ascochyta (Ascochyta) category kind, such as Ascochyta lentis;
Aspergillus, such as aspergillus flavus;
Cladosporium category kind, such as draft branch spore (Cladosporium herbarum);
Cochliobolus category category kind, such as standing grain cochliobolus;
(conidial form:Drechslera, Syn:The compacted spore bacterium of length);
Colletotrichum category kind, such as hair core anthrax-bacilus (Colletotrichum coccodes);
Fusarium category kind, such as yellow fusarium;
Gibberella category kind, such as beautiful another name for Sichuan Province multitude is red mould;
Shell ball spore category (Macrophomina) category kind, such as Kidney bean shell ball spore (Macrophomina
phaseolina) ;
Small setting-out shell belongs to strain, for example, avenge rotten small setting-out shell;
Penicillium category kind, such as penicillium expansum;
Phaeosphaeria strains, such as Phaeosphaeria nodorum;
Phoma (Phoma) category kind, such as black embryo Phoma sp (Phoma lingam);
Phomopsis (Phomopsis), such as soybean Phomopsis (Phomopsis sojae);
Phytophthora category kind, such as Phytophthora cactorum (Phytophthora cactorum);
Nuclear cavity Pseudomonas category kind, such as wheat class nuclear cavity bacteria (Pyrenophora graminea);
Pyricularia Sacc. (Pyricularia) category kind, such as Magnaporthe grisea (Pyricularia oryzae);
Pythium kind, such as Pythium ultimum;
Rhizoctonia category kind, such as Rhizoctonia solani Kuhn;
Rhizopus (Rhizopus) category kind, such as Rhizopus oryzae (Rhizopus oryzae);
Bulbil category (Sclerotium) category kind, such as Sclerotium rolfsii (Sclerotium rolfsii);
Core coral Pseudomonas (Typhula) category kind, such as meat spore core coral bacterium (Typhula incarnata);
Verticillium (Verticillium) category kind, such as verticillium dahliae (Verticillium dahliae).
Bactericidal composition of the invention also has excellent bactericidal effect to the bacterium of existing bactericide display tolerance.For example
Ash arrhizus bacteria（Botrytis cinerea）, sugar beet leaf spot bacteria（Cercospora beticola）, apple black star bacteria
（Venturia inaequalis）, pear cucumerinum（Venturia nashicola）Deng.
A kind of plant pathogenic fungi of control plant, plant part, plant propagation material and the plant organ for then growing
Method, including by the amount of application of the bactericidal composition of the invention effective and basic plant-less toxicity with agronomy with seed at
The methods such as reason, foliage applying, stem are applied, are impregnated with, instiling, pouring into a mould, spraying, spraying, dusting, distribution or smoke be administered to plant,
Plant part, plant propagation material or plant are being grown or needed in the soil or cultivation medium for growing wherein.
Bactericidal composition of the invention can be spread by Seed Treatment, cauline leaf, soil application or it is used for ponds etc. and
The prevention and treatment of the various diseases for being produced when cultivation includes the agriculture garden crop of flowers, lawn, herbage.
The present invention provides a kind of method for preventing and treating plant pathogen, and bactericidal composition is acted on into pathogenic bacteria and/or its ring
In border, or plant, plant parts, plant propagation material, soil, region, material or space.
Bactericidal composition of the invention can be used for the plant device protected plant part, plant propagation material and then grow
Official.
Bactericidal composition of the invention, can process all plants and plant part." plant " refers to all plants and plant
Population, such as preferably with undesirable wild plant, cultivated plant and plant variety (regardless of whether receiving plant variety or plant
Cultivate the protection of people's right).Cultivated plant and plant variety can be the plants obtained by Sterile culture and breeding method, this
A little methods can be aided with or be supplemented with one or more biological technique method, such as using dihaploid, protoplast fusion, random
With orthomutation, molecule or genetic marker, or use bioengineering and genetic engineering method.Plant part refers to all of plant
Above and below the ground part and organ, such as bud, leaf, Hua Hegen, such as leaf, needle, stem, branch, flower, fructification, fruit and kind
Son and root, bulb and rhizome.Crop and nourish and generate and case of propagation material, for example, transplant, bulb, rhizome, running roots
Plant part is fallen within seed.
Term " plant propagation material " is interpreted as referring to all plant parts for having a fertility, such as seed, and it can be used
In breeding the latter, and vegetable matter such as cuttage bar or stem tuber（Such as potato）.Therefore, plant used herein
Part includes plant propagation material.It is mentioned that such as seed, root, fruit, stem tuber, bulb, rhizome and plant part.Treat
The germination plant and effective plant suppressed after being germinateed from soil or after emerging.Young plant can before transplantation by being impregnated into
Row whole or Local treatment are protected.
Currently preferred propagating materials is seed.The method of Seed Treatment, for example, can there are, diluent liquid or solid
The medicament of shape or seed is directly immersed in liquid condition solution the method for making medicament be impregnated with seed without dilution, by solid
Medicament or liquid preparation are mixed with seed, be coated treatment make the surface of the seed adhere to medicament method, plantation
Simultaneously near seed sprinkling etc. method.
Plant part and the plant organ for then growing are by any of the plant propagation material such as plant of seed generation
Part.Plant part, plant organ and plant can also be benefited from and be applied to plant propagation material institute by by bactericidal composition
The pathogenic damage protection of acquisition.The plant organ grown behind certain plants part and some places can also regard plant propagation as
Material, its own can be applied with bactericidal composition（Or treatment）；So as to by the plant part through processing and the plant through processing
Plant, other plant parts and the other plant organs that organ is produced can also be benefited from and applied by by bactericidal composition
With.
Bactericidal composition of the invention can also be used to prevent or control soil or cultivate various in medium causing a disease or saprophytic
Fungi and bacterium.The example of the aquacultural fungal pathogen of soil-borne includes Alternaria（Alternaria spp.）, Ascochyta
(Ascochyta spp.), Botrytis cinerea（Botrytis cinerea, Cercospora（Cercospora spp., ergot
（Claviceps purpurea）, standing grain cochliobolus（Cochliobolus sativus）, Colletotrichum（colletotrichum
Spp., Epicoccum（Epicoccum spp., F.graminearum schw（Fusarium graminearum）, rice evil seedling chain spore
（Fusarium moniliforme）, fusarium oxysporum（Fusarium oxysporum, fusarium moniliforme（Fusarium
proliferatum）, fusariun solani (Fusarium solani) ties up glue chain spore (Fusarium subglitinans), long compacted
Spore belongs to (Helminthosporium spp), rotten microtorr bacterium (Microdochium nivale) of snow, Penicillium (Pencillium
Spp), Phoma (Phoma spp.), wheat class nuclear cavity bacteria (Pyrenophora graminea), rice blast Pyricularia Sacc.
(Pyricularia oryzae), Rhizoctonia solani Kuhn (Rhizoctonia solani), Rhizoctonia cerealis (Rhizoctonia
Cerealis), Sclerotinia (Sclerotinia spp.), Septoria (Septoria spp.), silk axle smut
(Sphacelotheca reilliana), Tilletia (Tilletia spp.), meat spore core coral bacterium (Typhula
Incarnate), hidden bar smut (Urocystis occulta), Ustilago (Ustilago spp.) or Verticillium
(Verticillium spp.)。
Soil germ has rhizoctonia solani, sickle-like bacteria, phytophthora, bacterium of dampinging off, root rot, pythium spp, botrytis cinerea, soft-rot fungi
Deng.In general, soil germ can produce a large amount of thalline, as long as condition is favourable to pathogen growth development, host is sense
Disease, germ just with amount reproduction and can infect host, and in the presence of susceptible host, these germs can just enter lasting
The phase of causing a disease, the amount reproduction diffusion with the continuous cropping of crop, but nutrient is depleted or edaphic condition such as temperature, humidity etc. afterwards
When unfavorable to germ, germ can enter rest period again.When susceptible host does not exist, soil-borne disease bacterium can also survive in soil
Get off, in addition to soil germ has extensive host range, moreover it is possible to survived on the root surface of non-host or the broken branches and fallen leaves, with it
It is undivided with saprophytic competitiveness.But different germs are discrepant, as sickle-like bacteria almost can be unlimited in soil
Phase survives.
Cultivation medium of the present invention is the supporter for referring to make crops take root, grow, for example：Soil, water etc.,
Specific raw material can using such as sand, float stone, vermiculite, diatomite, agar-agar, gelling material, polymer substance, asbestos,
Wood chip, bark etc..
To the method in soil using medicament, for example, liquid preparation is diluted in water or do not diluted and be directly applied to plant
The medium method in the root of body or the rice seedling bed of seedling, the side in the rice seedling bed of the root of plant or seedling is disseminated to by granule
Method has the method that pulvis, water dispersible granules etc. are sprayed in soil and are integrally mixed with soil prior to seeding, and sowing is preceding or plants
In being sprayed on implantation hole, seed furrow after pulvis, water-dispersible grain dilution agent before kind plant, in method sowed etc..
Another object of the present invention, there is provided a kind of control plant, plant part, plant propagation material and then grow
The method of the plant pathogenic fungi of plant organ, the method include by bactericidal composition of the invention with agronomy it is effective and substantially without
Phytotoxic amount of application is applied with Seed Treatment, foliage applying, stem, is impregnated with, instiled, poured into a mould, sprayed, sprayed, dusting, distribution
Or the method such as smoke is administered to plant, plant part, plant propagation material or plant and is growing or needing what is grown wherein
In soil or cultivation medium.
Bactericidal composition of the invention can be applied by different processing methods, and these methods are for example：
- liquid comprising the bactericidal composition is sprayed onto the aerial part of the plant；
- dusting, mixes particle or powder in soil, in surrounding plants sprinkling, and in tree injection or the situation of smearing
Under；
- seed of plant is coated or film coated.
- for postharvest fruit and vegetable anti-corrosive fresh-keeping when, 200-2000 times of liquid of usual dilute with water, leaching fruit after leach.
The present invention provides a kind of method for preventing and treating plant pathogen, can treat, prevent or method of eradication.
Bactericidal composition of the invention can be made into common dosage form, such as missible oil, wettable powder, suspending agent, liquid
The dosage forms such as agent, granule, seed coat agent are used, its amount of application, mixing ratio, meteorological condition according to active ingredient, medicament
Form, Dressing date, application process, using place, prevent and kill off the different and variant of object noxious livings, objective crop etc..
It is a kind of prevent and treat plant pathogen method, by Picarbutrazox and Prochloraz be administered simultaneously or apply respectively,
Or sequential application.
Treatment in accordance with the present invention is there may be super plus (" collaboration ") effect.For example, sterilized group used according to the present invention
The rate of application of compound and/or widen its field of activity and/or increase its activity, it is possible to obtain following effect：More preferable plant
Growth, the tolerance to high temperature or low temperature increases, and the tolerance to arid or water or soil salt content increases, and performance of blooming is carried
It is high, it is easier to harvest, the maturation of quickening, yield rate higher, bigger fruit, plant height higher, the color of leaf is more
It is green, to bloom earlier, the quality or nutritive value of the product of results are higher, and sugared concentration is higher in fruit, the storage of the product of results
More preferably, these benefits have exceeded the effect actually estimated for stability and/or processability.
Processing method of the invention can be additionally used in process propagating materials such as stem tuber or rhizome, and can be used for treatment seed,
Seedling or transplanting (pricking out) seedling and plant or transplanting plant.The processing method can also be used for processing root.The present invention
Processing method can also be used for processing the aerial part of plant such as about the doing of plant, stem or stalk, leaf, flower and fruit.
- generally for leaf portion treatment：0.1-10000g/ha, preferably 10-1000 g/ha, more preferably 50-500 g/ha；It is right
For dipping or administration of instiling, the dosage can also even be reduced, particularly when using inert base such as asbestos or pearl
During rock；
- for Seed Treatment：2-5000g/100kg seeds, preferably 3-1000g/100kg seeds；
- for soil or treatment used for ponds：0.1-10000g/ha, preferably 1-1000g/ha；
- fresh-keeping for postharvest fruit and vegetable, 200-2000 times of liquid can be diluted, leached after leaching fruit.
Above-mentioned dosage is only general exemplary dose, and those skilled in the art can be according to actual feelings during actual administration
Condition and needs, the seriousness especially in accordance with the property and germ of pending plant or crop adjust rate of application.
Picarbutrazox of the invention is combined with Prochloraz/co-administered.Including separating, sequentially or simultaneously applying
Picarbutrazox and Prochloraz.Preferably, the Picarbutrazox is combined as comprising Picarbutrazox with Prochloraz
With the form of the composition of Prochloraz.
Composition of the invention can be based on dosage form, i.e., each material is blended in composition, composition into
Point can also unit dose form provide, use it is preceding mix in bucket or tank, be then diluted to required concentration.Wherein preferably with this hair
Based on the dosage form of bright offer.
As a further improvement on the present invention, bactericidal composition of the invention can be configured to any agent for agriculturally allowing
Type.
As a further improvement on the present invention, the formulation of bactericidal composition of the invention is suspending agent, seed coat agent, wettable
It is pulvis, water dispersible granules, microcapsule suspending agent, coated granule, extrusion granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet, super
Low capacity liquor.
In bactericidal composition of the present invention, lived comprising Picarbutrazox and Prochloraz, filler and/or surface
Property agent.
The content of bactericidal composition of the present invention, wherein Picarbutrazox and Prochloraz accounts for bactericidal composition
5%-90%。
The content of described bactericidal composition, wherein Picarbutrazox and Prochloraz accounts for the 10%- of bactericidal composition
80%。
The content of described bactericidal composition, wherein Picarbutrazox and Prochloraz accounts for the 20%- of bactericidal composition
60%。
According to the present invention, term " filler " refers to can be combined with reactive compound or combines to make it easier for being administered to
Object（Such as plant, crop or careless class）Natural or synthetic organic or inorganic compound.Therefore, the filler is preferably
It is inert, at least should be agricultural acceptable.The filler can be solid or liquid.
The nonactive medium that can be used in the present invention both can be that solid can also be liquid, can be as solid matchmaker
What dielectric material was used has for example：Phyteral powdery type（Such as soy meal, starch, grain dust, wood powder, bark powder, sawdust, walnut
The particle of shell powder, wheat bran, cellulose powder, coconut husk, corncob and tobacco stem, extracts residue after plant essence etc.）, paper
, sawdust, crush synthesized polymer body, the clay class of synthetic resin etc.（Such as kaolin, bentonite, acid china clay etc.）, talcum powder
Class.Silica（Such as diatomite, silica sand, mica, aqueous silicic acid, calcium silicates）, activated carbon, natural mineral matter class（Float stone, Lv Po
Thread stone and zeolite etc.）, fire diatomite, sand, plastics medium etc.（Such as polyethylene, polypropylene, polyvinylidene chloride etc.）, chlorination
The chemical fertilizer of inorganic mineral powder, ammonium sulfate, ammonium phosphate, urea, the ammonium chloride of potassium, calcium carbonate, calcium phosphate etc. etc., soil
Fertilizer, these materials can be used alone or two or more is mixed.
Can be selected in llowing group of materials as liquid media materials'use, such as water, alcohol type（Such as first
Alcohol, ethanol, isopropanol, butanol, ethylene glycol etc.）, ketone（Such as acetone, methyl ethyl ketone, isobutyrone, cyclohexanone
Deng）, ethers（Such as ether, dioxanes, methylcellulose, tetrahydrofuran etc.）, aliphatic hydrocarbon class（Such as kerosene,
Mineral oil etc.）, aromatic hydrocarbons class（Such as benzene,toluene,xylene, solvent naphtha, alkylnaphthalene, chlorinated aromatic hydrocarbons, chloro fat
Fat hydrocarbon, chlorobenzene, etc.）, halogenated hydrocarbon class, amide-type, sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, animal oil etc..
To emulsify active ingredient compound, dispersion and/or soak, it is possible to use surfactant for example can be with
Enumerate AEO, polyoxyethylene alkylaryl ether, polyoxyethylene higher fatty acid esters, polyoxyethylene alcohol or phenol
Phosphate, the fatty acid ester of polyalcohol, alkane aromatic sulfonic acid, naphthalene sulfonic acid polymer, lignosulfonates, the branch shape of macromolecule comb shape are total to
Polymers, butyl naphthalene sulfonate, alkylaryl sulfonates, sodium alkylsulfosuccinates, grease, fatty alcohol and ethylene oxide condensation
The polyacrylates such as thing, alkyltaurate, protein hydrolysate.Suitable oligosaccharide thing or polymer, such as based on independent
Vinyl monomer, acrylic acid, polyoxyethylene and/or polyoxypropylene or its with for example（It is polynary）Alcohol or（It is polynary）The combination of amine.
To make active ingredient compound dispersion stability, attachment and/or combining, such as xanthans, silicic acid can be used
Magnalium, gelatin, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid（Such as cephalin and lecithin）With
And the adjuvant such as synthetic phospholipid, bentonite, sodium lignin sulfonate.
The wherein optional spent glycol of antifreezing agent, propane diols, glycerine, sorbierite.As the deflocculant of suspension product
The adjuvant of such as naphthalene sulfonic acid polymer, polymeric phosphate etc. can be used.
Organic silicon defoamer can be used as defoamer.
The colouring agent that can be used, such as inorganic pigment, such as iron oxide, titanium oxide and Prussian blue；And organic pigment/
Dyestuff：Alizarin dyes, azo dyes and metallized phthalocyanine dye；And trace element, such as molysite, manganese salt, boron salt, mantoquita, cobalt
Salt, molybdenum salt and zinc salt.
Optionally, can also include other annexing ingredients, for example protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent,
Stabilizer, screening agent.
The reactive compound can be mixed and prepared by the preparation of the invention by known way with conventional additives.
The conventional additives such as conventional extender and solvent or diluent, emulsifying agent, dispersant, and/or adhesive or fixative,
Wetting agent, waterproofing agent, if it is desired, drier and colouring agent, stabilizer, pigment, defoamer, preservative, increasing can also be included
Thick dose, water and other processing aids.
Bactericidal composition of the invention not only includes can be by suitable equipment as spraying or dusting equipment are applied to immediately
Pending object, and the concentration commercial composition for needing to be diluted is additionally included in before being applied to object.
It is of the invention to be applied with other active ingredient combinations containing Picarbutrazox and Prochloraz, for example for
Expand activity profile or prevent from forming resistance.Described other active components such as fungicide, bactericide, attractant, kill insect
Agent, acaricide, nematicide, growth regulator, herbicide, safener, fertilizer or semiochemical etc..
Reactive compound Picarbutrazox and Prochloraz can be administered simultaneously, or apply respectively, or sequential application, separate
Using when order on prevent and treat result generally without influence.
Composition of the invention can be based on dosage form, i.e., each material is blended in composition, composition into
Point can also unit dose form provide, use it is preceding mix in bucket or tank, be then diluted to required concentration.Wherein preferably with this hair
Based on the dosage form of bright offer.
In the case where reactive compound is reduced using total amount, have to harmful fungoid improves activity to bactericidal composition of the invention
（Synergistic）.And bactericidal composition of the invention shows that the bacterium of tolerance also has excellent killing to existing bactericide
Bacterium effect.
A kind of bactericidal composition of the present invention, said composition carries out binary built by by Picarbutrazox and Prochloraz,
So that the mixture for obtaining has gain effect in prevention effect, and fungicidal spectrum is expanded, served the multiplex work of a medicine
With effectively slowing down or avoid germ to develop immunity to drugs.The bactericidal activity of bactericidal composition of the invention is than each reactive compound
It is active plus and it is considerably higher, there is unpredictable, necessary being cooperative effect, and be not only the supplement of activity.
When reactive compound is present in bactericidal composition of the invention with specific weight ratio, cooperative effect is especially bright
It is aobvious.But, the weight ratio of the reactive compound in bactericidal composition of the present invention can change within the specific limits.
Can have greater activity and the more long bactericidal composition of activity holding the invention provides a kind of.This sterilized group
Compound has relatively low-dose, while the toxicity of the bactericidal composition is relatively low, fruits and vegetables and seed with fungal disease is carried out
Control.
Specific embodiment
The invention will be further elaborated to first pass through specific example of formulations below.
Example of formulations
Embodiment 1：40% Picarbutrazox Prochloraz wettable powders
Picarbutrazox 10%, Prochloraz 30%, lignosulfonates 6%, spaonin powder 4%, attapulgite adds to 100%, will
Aforementioned formula material mixes, the uniform stirring in stirred tank, is remixed after airslide disintegrating mill uniformly, that is, be obtained 40%
Picarbutrazox Prochloraz wettable powders.
Embodiment 2：50% Picarbutrazox prochloraz-manganese chloride complex wettable powders:
Picarbutrazox 5%, prochloraz-manganese chloride complex 45%, naphthalene sulfonic acid-formaldehyde condensation product 8%, tea seed cake 5%, kaolin adds to 100%,
Aforementioned formula material is mixed, the uniform stirring in stirred tank, be well mixed after airslide disintegrating mill, be obtained 50%
Picarbutrazox prochloraz-manganese chloride complex wettable powders.
Embodiment 3：51% Picarbutrazox Prochloraz wettable powders
Picarbutrazox 1%, Prochloraz 50%, AEO 7%, wetting and penetrating agent F 5%, diatomite is added to
100%, aforementioned formula material is mixed, the uniform stirring in stirred tank, it is being well mixed after airslide disintegrating mill, it is obtained 51%
Picarbutrazox Prochloraz wettable powders.
Embodiment 4：32% Picarbutrazox Prochloraz water dispersible granules
Picarbutrazox 2%, Prochloraz 30%, alkyl benzene sulfonate calcium salt 8%, Nekal BX 6%, ammonium sulfate 2%, bentonite adds
To 100%, aforementioned formula material is uniformly mixed, with micro jet, through mediating, being subsequently adding fluidized-bed granulation dryer
In granulated, dry, sieve after be mixed to prepare 32% Picarbutrazox Prochloraz water dispersible granules through sampling analysis.
Embodiment 5：60% Picarbutrazox Prochloraz water dispersible granules
Picarbutrazox 20%, Prochloraz 40%, aliphatic acid polyethenoxy ether 7%, lauryl sodium sulfate 4%, aluminium chloride
2.8%, kaolin adds to 100%, and aforementioned formula material is uniformly mixed, with micro jet, through mediating, being subsequently adding fluidisation
Bed granulating and drying machine in granulated, dry, sieve after be mixed to prepare 60% Picarbutrazox Prochlorazs through sampling analysis
Water dispersible granules.
Embodiment 6：90% Picarbutrazox Prochloraz water dispersible granules
Picarbutrazox 20%, Prochloraz 70%, octylphenol polyethylene oxyethylene group ether sulfate 1%, neopelex
1%, sodium carbonate 1%, white carbon adds to 100%, and aforementioned formula material is uniformly mixed, with micro jet, through mediating and then
Add granulated in fluidized-bed granulation dryer, dry, sieve after through i.e. prepared 90% Picarbutrazox of sampling analysis
Prochloraz water dispersible granules.
Embodiment 7：45% Picarbutrazox Prochloraz suspending agents
Picarbutrazox 5%, Prochloraz 40%, polycarboxylate 6%, silicone oil 0.3%, xanthans 0.9%, diethylene glycol (DEG) 2.5%, go from
Sub- water adds to 100%, remaining component after thickener and antifreezing agent are mixed in addition to active ingredient is crossed, and mixes by high speed shear
Uniformly, active ingredient is added, ball milling 2 ~ 3 hours in ball mill make particle diameter all below 5 μm, that is, is obtained 45%
Picarbutrazox Prochloraz suspending agents.
Embodiment 8：55% Picarbutrazox Prochloraz suspending agents
Picarbutrazox 5%, Prochloraz 50%, naphthalene sulfonic acid-formaldehyde condensation product 6%, hydroxyethyl cellulose 0.7%, silicone chemical combination
Thing 0.1%, polyethylene glycol 2%, deionized water adds to 100%, remaining group after thickener and antifreezing agent are mixed in addition to active ingredient
Point, it is well mixed by high speed shear, add active ingredient, ball milling 2 ~ 3 hours in ball mill, make particle diameter all 5 μm with
Under, that is, 55% Picarbutrazox Prochloraz suspending agents are obtained.
Embodiment 9：40% Picarbutrazox Prochloraz suspending agents
Picarbutrazox 15%, Prochloraz 25%, lignosulfonates 8%, Magnesiumaluminumsilicate 1%, silicone 0.2%, glycerine
2.8%, deionized water adds to 100%, remaining component after thickener and antifreezing agent are mixed in addition to active ingredient, is cut by high speed
Cut well mixed, add active ingredient, ball milling 2 ~ 3 hours in ball mill make particle diameter all below 5 μm, i.e., prepared 40%
Picarbutrazox Prochloraz suspending agents.
Embodiment 10：5% Picarbutrazox Prochloraz suspension emulsions
Picarbutrazox 1%, Prochloraz 4%, alkyl benzene sulfonate calcium salt 7%, methylcellulose 1.2%, propane diols 2.4%, C8~10
Aliphatic alcohols 0.4%, Tween 80 7%, water adds to 100%；Added in the continuous phase containing Prochloraz finely ground
The suspended phase of Picarbutrazox, is mixed to prepare 5% Picarbutrazox Prochloraz suspension emulsions.
Embodiment 11：20% Picarbutrazox Prochloraz suspension emulsions
Picarbutrazox 5%, Prochloraz 15%, lignosulfonates 6%, xanthans 0.8%, ethylene glycol 2.5%,
SOLVESSOTM100 15%, silicone oil 0.2%, 600# phosphates 5%, water adds to 100%.Mill is added in the continuous phase containing Prochloraz
The suspended phase of very thin Picarbutrazox is obtained, 20% Picarbutrazox Prochloraz suspension emulsions are mixed to prepare.
Embodiment 12：30% Picarbutrazox Prochloraz suspension emulsions
Picarbutrazox10%, Prochloraz 20%, naphthalene sulfonic acid-formaldehyde condensation product 7%, spaonin powder 3%, phenolic resin 1.1%, three is sweet
Alcohol 2%, silicone 0.1%, agriculture breast 400#6%, water adds to 100%, is added in the continuous phase containing Prochloraz finely ground
The suspended phase of Picarbutrazox, is mixed to prepare 30% Picarbutrazox Prochloraz suspension emulsions.
Embodiment 13：10% Picarbutrazox Prochloraz microemulsions
Picarbutrazox 2%, Prochloraz 8%, N- methyl pyrrolidones 6%, oxirane-propylene oxide block copolymer
4%th, alkyl biphenyl ether disulfonic acid magnesium salts 5%, silicone compound 0.4%, toluene 3%, propane diols 2%, epoxychloropropane 1.1%, go
Ionized water adds to 100%, is made 10%Picarbutrazox Prochloraz microemulsions.
Embodiment 14：5% Picarbutrazox Prochloraz microemulsions
Picarbutrazox 1%, Prochloraz 4%, cyclohexanone 5%, agriculture breast 500#4%, Nongru-700 #5%, C8~10Aliphatic alcohols
0.2%th, ethyl acetate 2.5%, polyethylene glycol 2%, tributyl phosphate 1.4%, deionized water add to 100%, are made 5%
Picarbutrazox Prochloraz microemulsions.
Embodiment 15：50% Picarbutrazox prochloraz-manganese chloride complex water dispersible granules
Picarbutrazox 10%, prochloraz-manganese chloride complex 40%, octylphenol polyethylene oxyethylene group ether sulfate 1%, DBSA
Sodium 1%, sodium carbonate 1%, white carbon adds to 100%, and aforementioned formula material is uniformly mixed, with micro jet, through mediating, so
Add afterwards granulated in fluidized-bed granulation dryer, dry, sieve after through sampling analysis i.e. prepared 50%
Picarbutrazox prochloraz-manganese chloride complex water dispersible granules.
Embodiment 16：10% Picarbutrazox prochloraz aqueous emulsions
Picarbutrazox 5%, Prochloraz 5%, 600# phosphates 4%, propyl alcohol 7%, agriculture breast 600#3%, xanthans 0.7%, the third two
Alcohol 2.4%, toluene 4%, deionized water add to 100%, are made 10% Picarbutrazox prochloraz aqueous emulsions.
Embodiment 17：6% Picarbutrazox Prochloraz missible oil
Picarbutrazox 1%, Prochloraz 5%, ethoxylated castor oil 5%, calcium dodecyl benzene sulfonate 3%,
SOLVESSOTM 200 add to 100%, stir to transparent homogeneous phase is obtained, and obtain 6% Picarbutrazox Prochlorazs breast
Oil.
Embodiment 18：40%Picarbutrazox Prochloraz microcapsule suspension-suspendinagent agents
Picarbutrazox 10%, Prochloraz 30%, Synperonic PE/64 15%, citric acid 0.05%, water 10%, PAPI
20%, SOLVESSOTM100 5%, dispersant LFH0.15%, defoamer 0.16%, urea 5.5%；Water complements to 100%；
By PAPI, Prochloraz, SOLVESSOTM100 oil phases for being formed are added in the aqueous solution containing Synperonic PE/64, form emulsus
Liquid.Then heat and be incubated and add catalyst reaction 2 hours at 50 DEG C.The microcapsules of Prochloraz is obtained after cooling.
Synperonic PE/64, dispersant LFH, defoamer, urea, Picarbutrazox and water are mixed in proportion, and through sand
Mill, is prepared into suspending agent.The Prochloraz microcapsules that will be obtained is added in the suspending agent of Picarbutrazox, is uniformly mixing to obtain
40%Picarbutrazox Prochloraz microcapsule suspension-suspendinagent agents.
The 35%Picarbutrazox prochloraz-manganese chloride complex seed coat agents of embodiment 19
Picarbutrazox 5%, prochloraz-manganese chloride complex 30%, AEO sulfosuccinic acid monoesters disodium 10% changes
Property calcium lignosulfonate 5%, xanthans 1%, bentonite 1%.Glycerine 5%,
PVP-K30 1%, complements to 100%, and above-mentioned each component is mixed in proportion, and through being sanded, is prepared into 35%
Picarbutrazox prochloraz-manganese chloride complex seed coat agents.
The 50%Picarbutrazox Prochloraz coated granules of embodiment 20
Picarbutrazox 10%, Prochloraz 40%, polyethylene glycol 3%, the silicic acid 1% of high degree of dispersion,
Calcium carbonate complements to 100%, in a mixer, by levigate active component even spread to the load soaked by polyethylene glycol
On body, the dust-free coated granules agent of 50%Picarbutrazox Prochlorazs can be obtained in this way.
Be well mixed for Picarbutrazox 30% and Prochloraz 70% by embodiment 21.
Be well mixed for Picarbutrazox 20% and Prochloraz 80% by embodiment 22.
Above example proportioning is weight per distribution ratio.
Biological test example：
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is exploitation at present and development novel pesticide and preventing and treating agriculturally resistance
A kind of effective and quick way of germ.After the pestsides synthesis of different cultivars, three kinds of type of action are typically exhibited：It is added and makees
With, synergistic effect and antagonism.But which kind of effect be specially, it is impossible to predict, only just be can know that by many experiments.Compounding
Synergy is formulated well, due to significantly improving actual prevention effect, reduces the usage amount of agricultural chemicals, so as to greatly delay
The generation of resistance.
First, virulence test：
The toxicity index of each medicament and the co-toxicity coefficient of mixture are calculated according to the abundant methods of Sun Yun（CTC values）, when CTC≤80, then combine
Thing shows antagonism, when 80<CTC<120, then composition show summation action, when CTC >=120, then composition performance
Go out synergistic effect.
Actual measurement toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
B in the percentage composition+B medicament toxicity index * mixtures of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixtures
Percentage composition
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixture theoretical toxicity index (TTI) * 100.
Experiment 1：The toxicity test of cucumber downy mildew
Selected from the cucumber seedling that growing way is consistent, sprayed under 50PSI pressure with potter spray towers, per basin about 5mL, each medicine
Agent sets 12 concentration gradients.24h connects bacterium after chemicals treatment, and the cucumber downy mildew leaf that will pick up from field is uniform above cucumber seedling
Shake off conidium to be inoculated with, then cucumber seedling is put into greenhouse and is cultivated.Morbidity after 7d according to cucumber downy mildew is classified
Standard complete stool investigates disease index, and calculates prevention effect, and concentration EC50 in suppressing then is calculated with least square method, then according to grandson
Yun Peifa calculates co-toxicity coefficient (CTC).
Table 1
As known from Table 1, Picarbutrazox and Prochloraz are preventing the weight proportion 10 of cucumber downy mildew:1-1:50 scope
In when, co-toxicity coefficient is all higher than 120, illustrates that both show as gain effect at mixture in the range of this.
Experiment 2：The toxicity test of tomato blight
Selected from the tomato seedling that growing way is consistent, each treatment supplies examination leaf seedling from 3 basins, with potter spray towers under 50PSI pressure
Spraying, per basin about 5mL, each medicament sets 12 concentration gradients.24h connects bacterium after chemicals treatment, will pick up from the tomato in field
Epidemic disease leaf is uniformly shaken off conidium above tomato seedling and is inoculated with, and then tomato seedling is put into greenhouse and is cultivated.Pressed after 7d
Morbidity grade scale complete stool according to tomato blight investigates disease index, and calculates prevention effect, is then calculated with least square method
Concentration EC50 in suppression, then calculate co-toxicity coefficient (CTC) according to the abundant methods of Sun Yun.
Table 2：Virulence test result of the present invention on preventing and treating tomato blight
As known from Table 2, Picarbutrazox and prochloraz-manganese chloride complex are preventing the weight proportion 10 of tomato blight:1-1:50 model
When enclosing inner, co-toxicity coefficient is all higher than 120, illustrates that both mixtures in the range of this show as gain effect.
Experiment 3：The toxicity test of Penicillium italicum
Using suppression mycelial growth rate method：Experiment target is designated as Penicillium italicum.
By Picarbutrazox and Prochloraz respectively use acetone solution, then with 0.1% the Tween-80 aqueous solution dilute match somebody with somebody
The liquid of series concentration is made, 6mL to the conical flask of sterilizing is drawn respectively in superclean bench, 50 DEG C or so of horse is added
Bell potato glucose agar medium（PDA）54mL, pours into 4 plates of diameter 9cm after shaking up, be made containing for 4 respective concentrations
Malicious culture medium；The Picarbutrazox of different ratio and Prochloraz series concentration compound solution are made and contained with same method
Malicious culture medium.The Penicillium italicum bacterium of 2 days will be cultivated, bacterium block is broken into colony edge with the card punch of diameter 5mm, use transfer needle
Bacterium block is moved to the toxic PDA culture medium center being configured in advance, culture in 25 DEG C of incubators is subsequently placed in, often treatment repeats 4
It is secondary.After 3 days, each treatment colony diameter cm is measured using crossing method slide calliper rule, obtain correction and suppress percentage.Each bacterium colony
Two diameters are surveyed in right-angled intersection, and bacterium colony size is represented with its average.Then colony growth inhibiting rate is obtained as the following formula：
Then concentration EC in suppressing is calculated with least square method50, then calculate co-toxicity coefficient according to the abundant methods of Sun Yun（CTC）.
Table 3：To the virulence test result of Penicillium italicum
As known from Table 3, the combination preventing and treating Penicillium italicum of Picarbutrazox and Prochloraz is in proportioning 10:1-1：50 scope
In when, co-toxicity coefficient is all higher than 120, illustrates that both show as gain effect at mixture in the range of this.
Experiment 4：The toxicity test of rice seedling blight
Selected from the rice seedling that growing way is consistent, each treatment supplies examination leaf seedling from 3 basins, with potter spray towers in 50PSI pressure
Lower spraying, per basin about 5mL, each medicament sets 12 concentration gradients.24h connects bacterium after chemicals treatment, will pick up from the water in field
Rice damping-off leaf is uniformly shaken off conidium above rice seedling and is inoculated with, and then rice seedling is put into greenhouse and is trained
Support.Morbidity grade scale complete stool after 7d according to rice seedling blight investigates disease index, and calculates prevention effect, then with minimum
Square law calculates concentration EC50 in suppressing, then calculates co-toxicity coefficient (CTC) according to the abundant methods of Sun Yun.
Table 4：Virulence test result of the present invention on preventing and treating rice seedling blight
As known from Table 4, Picarbutrazox and Prochloraz are preventing the weight proportion 10 of rice seedling blight:1-1:50 scope
In when, co-toxicity coefficient is all higher than 120, illustrates that both show as gain effect at mixture in the range of this.
2nd, the evaluation of pesticide effectiveness：
When the effect of active compound combinations exceedes the summation of the effect when each reactive compound is administered alone, there is association
Same synergistic effect.The predictive role of two kinds of particular combinations of reactive compound can be used so-called " Colby formula " (referring to
S.R. Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide
Combinations ", Weeds 1967,15,20-22) it is calculated as below:If
X is the activity when the reactive compound A that consumption is mg/ha or concentration is mppm is used；
Y is the activity when the reactive compound B that consumption is ng/ha or concentration is nppm is used, and is expressed as accounting for untreated right
According to percentage；
E is the activity when the reactive compound A and B that consumption is m and n g/ha or concentration is m and n ppm is used,
So
If the activity of actual observation（O）More than expection activity（E）, then said composition has synergistic effect.
Following biological test example is used to illustrate the present invention.But, the present invention is not limited to these embodiments.
Experiment 5：Epidemic disease is tested（Tomato）The efficacy testing of/protectiveness
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent
Close, dilute with water concentrate to required concentration.
In order to test protectiveness activity, young plant is sprayed with certain rate of application with active agent preparations.In sprinkling
Coating dry after, plant is inoculated with the aqueous spore suspension of phytophthora infestans.Then the plant is placed on about 20
DEG C, in the incubate box that relative atmospheric humidity is 100%.
3 days after incubation, test result is evaluated.0% represents the drug effect equivalent to control sample, 100% drug effect
Indicate and occur without illness.
| Reactive compound | The rate of application of reactive compound, ppm | Actual drug effect, % | The desired value % that " Colby formula " is calculated |
| Picarbutrazox | 1 | 44 | - |
| Picarbutrazox | 100 | 89.4 | - |
| Prochloraz-manganese chloride complex | 10 | 0 | - |
| Prochloraz-manganese chloride complex | 25 | 5.9 | - |
| Prochloraz-manganese chloride complex | 50 | 13.9 | - |
| Prochloraz-manganese chloride complex | 1000 | 55.7 | - |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 100+10 | 100 | 89.4 |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 1+25 | 64.2 | 47.3 |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 1+50 | 68.3 | 51.7 |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 1+1000 | 73.6 | 75.2 |
Upper table clearly illustrated according to bactericidal composition of the invention, the weight of Picarbutrazox and prochloraz-manganese chloride complex
Than being 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of tomato blight in the range of 50, that is, there is cooperative effect.
Experiment 6：Epidemic disease is tested（Tomato）/ curative efficacy testing
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent
Close, dilute with water concentrate to required concentration.
In order to test therapeutical active, the spore suspension of phytophthora infestans is inoculated with to the tomato of 5-6 leaf phases.Then will be described
Prevented and treated 18 hours in the incubate box that plant is placed on about 20 DEG C, relative atmospheric humidity is 100%.After air-drying leaf, with activation
Compound preparation sprays young plant with certain rate of application, and is sprayed with the degree of the liquid that drips, and then makes in greenhouse
Its morbidity.Inoculation investigates occurring degree after 7 days.Test result is evaluated.0% represents the drug effect equivalent to control sample,
100% drug effect indicates occur without illness.
| Reactive compound | The rate of application of reactive compound, ppm | Actual drug effect, % | The desired value % that " Colby formula " is calculated |
| Picarbutrazox | 1 | 44 | - |
| Picarbutrazox | 100 | 84.4 | - |
| Prochloraz-manganese chloride complex | 10 | 0 | - |
| Prochloraz-manganese chloride complex | 25 | 0 | - |
| Prochloraz-manganese chloride complex | 50 | 5 | - |
| Prochloraz-manganese chloride complex | 1000 | 48.5 | - |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 100+10 | 100 | 84.4 |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 1+25 | 61.2 | 44 |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 1+50 | 66.3 | 46.8 |
| Picarbutrazox+ prochloraz-manganese chloride complexes | 1+1000 | 71.1 | 71.2 |
Upper table clearly illustrated according to bactericidal composition of the invention, the weight of Picarbutrazox and prochloraz-manganese chloride complex
Than being 10:1-1:It is higher than the drug effect being calculated to the actual drug effect of tomato blight in the range of 50, that is, there is cooperative effect.
Experiment 7：Downy mildew is tested（Grape）The efficacy testing of/protectiveness
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent
Close, dilute with water concentrate to required concentration.
In order to test protectiveness activity, young plant is sprayed with certain rate of application with active agent preparations.In sprinkling
Coating dry after, plant is inoculated with the aqueous spore suspension of Plasmopara viticola.Then the plant is placed on
About 20 DEG C, in the incubate box that relative atmospheric humidity is 100%.
3 days after incubation, test result is evaluated.0% represents the drug effect equivalent to control sample, 100% drug effect
Indicate and occur without illness.
| Reactive compound | The rate of application of reactive compound, ppm | Actual drug effect, % | The desired value % that " Colby formula " is calculated |
| Picarbutrazox | 1 | 26.9 | - |
| Picarbutrazox | 10 | 54.2 | - |
| Picarbutrazox | 50 | 92.6 | - |
| Prochloraz | 1 | 0 | - |
| Prochloraz | 25 | 7 | - |
| Prochloraz | 50 | 11 | - |
| Prochloraz | 1000 | 50.1 | |
| Picarbutrazox+ Prochlorazs | 10+1 | 66.1 | 54.2 |
| Picarbutrazox+ Prochlorazs | 1+25 | 58.2 | 32.0 |
| Picarbutrazox+ Prochlorazs | 1+50 | 62.1 | 34.9 |
| Picarbutrazox+ Prochlorazs | 1+1000 | 63.1 | 63.5 |
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of Prochloraz
10:1-1:It is higher than the drug effect being calculated to the actual drug effect of downy mildew of garpe in the range of 50, that is, there is cooperative effect, and
And the effect of cooperative effect is the most obvious.
Experiment 8：Downy mildew is tested（Grape）/ curative efficacy testing
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent
Close, dilute with water concentrate to required concentration.
In order to test therapeutical active, the spore suspension of Plasmopara viticola is inoculated with to the grape of 5-6 leaf phases.Then will
Prevented and treated 18 hours in the incubate box that the plant is placed on about 20 DEG C, relative atmospheric humidity is 100%.After air-drying leaf, with work
Property compound formulation young plant is sprayed with certain rate of application, and sprayed with the degree of the liquid that drips, then in greenhouse
In it is fallen ill.Inoculation investigates occurring degree after 7 days.Test result is evaluated.0% represents the medicine equivalent to control sample
Effect, 100% drug effect indicates occur without illness.
| Reactive compound | The rate of application of reactive compound, ppm | Actual drug effect, % | The desired value % that " Colby formula " is calculated |
| Picarbutrazox | 1 | 22.9 | - |
| Picarbutrazox | 10 | 48.2 | - |
| Picarbutrazox | 50 | 86.6 | - |
| Prochloraz | 1 | 0 | - |
| Prochloraz | 25 | 0 | - |
| Prochloraz | 50 | 11 | - |
| Prochloraz | 1000 | 51.3 | - |
| Picarbutrazox+ Prochlorazs | 10+1 | 29.5 | 22.9 |
| Picarbutrazox+ Prochlorazs | 1+25 | 43.7 | 22.9 |
| Picarbutrazox+ Prochlorazs | 1+50 | 49.3 | 31.3 |
| Picarbutrazox+ Prochlorazs | 1+1000 | 61.6 | 62.4 |
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of Prochloraz
10:1-1:It is higher than the drug effect being calculated to the actual drug effect of downy mildew of garpe in the range of 50, that is, there is cooperative effect, and
And the effect of cooperative effect is the most obvious.
Experiment 9：Antiseptic effect to preserving oranges and tangerines
Treatment oranges and tangerines picking time plucks fruit, rejects disease fruit and wound fruit, and fruit 1min is soaked with treatment liquid.Control clear water dipping.Respectively
Dried after treatment leaching fruit, next day loads the plastic box that surrounding is lined with newspaper, normal temperature laboratory storage.Check decayed fruit number within 7 days after treatment
And decayed fruit is rejected, while having weighed up fruit weight.And calculate preventive effect.
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of Prochloraz
10:1-1:In the range of 50, to the anti-corrosion of storage period oranges and tangerines, actual drug effect is higher than the drug effect being calculated, that is, there is collaboration and imitate
Should.
Experiment 10：Damping-off is tested（Paddy rice）/ curative efficacy testing
Solvent：24.5 pbw acetones
24.5 weight portion dimethylacetylamides
Emulsifying agent：1 weight portion alkylaryl polyglycol ether
In order to obtain the appropriate formulation of reactive compound, 1 Parts by weight Active compound is mixed with a certain amount of solvent and emulsifying agent
Close, dilute with water concentrate to required concentration.
In order to test therapeutical active, to the spore of the rice seedlings Inoculated Rice rhizoctonia solani of the 5-6 leaf phases in seedling-growing container
Water slurry, places 18 hours in the incubate box that 25 DEG C, relative atmospheric humidity are 100%.After air-drying leaf, active ingredient is used
Thing preparation sprays plant with certain rate of application, then it is fallen ill in greenhouse.Inoculation investigates occurring degree after 10 days.0%
The drug effect equivalent to control sample is represented, 100% drug effect indicates occur without illness.
| Reactive compound | The rate of application of reactive compound, ppm | Actual drug effect, % | The desired value % that " Colby formula " is calculated |
| Picarbutrazox | 1 | 25.9 | - |
| Picarbutrazox | 10 | 51.2 | - |
| Picarbutrazox | 50 | 89.8 | - |
| Prochloraz | 1 | 0 | - |
| Prochloraz | 25 | 0 | - |
| Prochloraz | 50 | 13 | - |
| Prochloraz | 1000 | 43.2 | - |
| Picarbutrazox+ Prochlorazs | 10+1 | 58.3 | 51.2 |
| Picarbutrazox+ Prochlorazs | 1+25 | 38.9 | 25.9 |
| Picarbutrazox+ Prochlorazs | 1+50 | 49.2 | 35.5 |
| Picarbutrazox+ Prochlorazs | 1+1000 | 55.3 | 57.9 |
Upper table clearly illustrates that, according to bactericidal composition of the invention, Picarbutrazox is with the weight ratio of Prochloraz
10:1-1:It is higher than the drug effect being calculated to the actual drug effect of rice seedling blight in the range of 50, that is, there is cooperative effect, and
And the effect of cooperative effect is the most obvious.
Claims (13)
1. a kind of bactericidal composition, it is characterised in that：The bactericidal composition includes that active component Picarbutrazox and miaow are fresh
The weight ratio of amine, Picarbutrazox and Prochloraz is 10:1-1:50, preferably 10:1-1:40, more preferably 10:1-
1:30, it is further preferably 1:1-1:25, it is further preferably 1:1-1:20, more preferably 1:1-1:15, more preferably 1:1-1:10.
2. bactericidal composition according to claim 1, it is characterised in that：The Picarbutrazox and Prochloraz quality
Sum accounts for the 5%-90% of the Bactericidal composite amount of substance, more preferably more preferably 10%-80%, 20%-60%.
3. bactericidal composition according to claim 1, it is characterised in that：Prochloraz includes Prochloraz metallic salt chemical combination
Thing, preferably prochloraz-manganese chloride complex.
4. bactericidal composition according to claim 1, it is characterised in that：The formulation of the bactericidal composition be suspending agent,
Seed coat agent, wettable powder, water dispersible granules, microcapsule suspending agent, coated granule, extrusion granule, missible oil, microemulsion, water
Emulsion, effervescent tablet, ultra low volume liquids.
5. bactericidal composition according to claim 1, it is characterised in that also comprising filler and/or surfactant.
6. it is a kind of prevent and treat plant pathogen method, it is characterised in that：Bactericidal composition described in claim 1 is acted on into cause
In germ and/or its environment, or plant, seed, soil, region, material or space.
7. method according to claim 6, it is characterised in that：Picarbutrazox and miaow described in claim 1 is fresh
Amine is administered simultaneously or applies respectively or sequential application.
8. the bactericidal composition described in claim 1 is used to prevent and treat the purposes of fungi and bacterium.
9. the bactericidal composition described in claim 1 is used to prevent and treat the purposes of fungi and bacterium in cereal, water fruits and vegetables.
10. the bactericidal composition described in claim 1 is used to protect the use of plant propagation material and the plant organ for then growing
On the way.
Caused a disease in preventing and treating soil or cultivation medium in the place that bactericidal composition described in 11. claims 1 is prevented and treated needed for being applied to
Or saprophytic fungi and the purposes of bacterium.
Bactericidal composition described in 12. claims 1 is used to prevent and treat the purposes of fruit vegetables storing period disease.
The plant pathogenic fungi of a kind of 13. control plants, plant part, plant propagation material and the plant organ for then growing
Method, it is characterised in that：The method is included the bactericidal composition described in claim 1 with agronomy effectively and substantially without plant poison
The amount of application of property is applied with Seed Treatment, foliage applying, stem, is impregnated with, instiled, poured into a mould, sprayed, sprayed, dusting, distribution or smoke
Etc. method be administered to plant, plant part, plant propagation material or plant growing or needing the soil that grows wherein or
In cultivation medium.
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| CN107372532A (en) * | 2017-08-11 | 2017-11-24 | 北京科发伟业农药技术中心 | The bactericidal composition of the urethane of pyrrole containing tetrazolium |
| CN110200067A (en) * | 2019-07-08 | 2019-09-06 | 桂林理工大学 | A kind of preservation method of okra |
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| CN106922709A (en) * | 2015-12-29 | 2017-07-07 | 浙江新农化工股份有限公司 | Compositions of the picarbutrazox with sterol biosynthesis inhibitor series bactericidal agent and its preparation and application |
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| CN102047898A (en) * | 2010-12-20 | 2011-05-11 | 陕西韦尔奇作物保护有限公司 | Bactericidal composition containing prochloraz and methoxy acrylic acid ester type compound |
| CN106922709A (en) * | 2015-12-29 | 2017-07-07 | 浙江新农化工股份有限公司 | Compositions of the picarbutrazox with sterol biosynthesis inhibitor series bactericidal agent and its preparation and application |
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