CN103329937A - Composition of bactericidal active components - Google Patents
Composition of bactericidal active components Download PDFInfo
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- CN103329937A CN103329937A CN2013102761820A CN201310276182A CN103329937A CN 103329937 A CN103329937 A CN 103329937A CN 2013102761820 A CN2013102761820 A CN 2013102761820A CN 201310276182 A CN201310276182 A CN 201310276182A CN 103329937 A CN103329937 A CN 103329937A
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Abstract
The invention relates to a novel composition of bactericidal active components. The composition includes a known oxime ether derivative and copper calcium sulphate. The composition is quite suitable for the control of plant phytopathogenic fungi and bacteria. The composition of bactericidal active components is characterized by containing a compound shown as a formula (I) and the copper calcium sulphate compound in a weight ratio of 1:1-1:100.
Description
Technical field
What a kind of fungicide active ingredient composition of the present invention related to is a kind of new Fungicidal active compound composition, comprises a kind of known oxime ether derivatives and copper sulphate calcium, and said composition is highly suitable for preventing and treating phytopathogenic fungi and bacterium.
Background technology
In horticultural crop and dry-land crop production, crop can run into multiple fungi or infecting of bacterium and various diseases, also often because of in the soil multiple cause a disease or saprophytic fungi (mould as corruption, epidemic disease is mould, Rhizoctonia solani Kuhn, sickle-like bacteria, botrytis cinerea etc.) and bacterium (soft-rot fungi etc.) infect harm, cause mashed kind, mashed root, seedling extremely.
Oxime bacterium ester (Trifloxystrobin) Chinese name makes oxime grass ester or trifluoro quick again, and its chemical name is (2Z)-2-methoxyimino-2-[2-[[1-[3-(trifluoromethyl) phenyl] ethyleneimino] the oxygen methyl] phenyl] methyl acetate, its structural formula is:
Oxime bacterium ester is the new fluorine-containing bactericide of successfully developing as the bactericide lead compound from natural products Strobilurins of a class.It is a kind of respiratory chain inhibitor; stop cell adenosine triphosphatase ATP synthetic by the electronics transmission of pinning between the cytochrome b and 1; thereby suppress its mitochondrial respiratory and bring into play bacteriostasis; it is the bactericide with chemical kinetics characteristic; can be shown the protection activity that provides excellent to plant by plant wax coat strong adsorption.Have efficient, wide spectrum, protection, treat, root out, infiltration, systemic activity, characteristic such as distribution fast; crop absorbs soon, it has interior absorption upwards in addition; so the resistance of rainwater washing against performance is good, the lasting period is long, therefore be considered to second generation methoxy acrylic bactericide.To 1,4-demethylation enzyme inhibitor, benzamides, the bacterial strain of dicarboxyl amine and benzimidazole generation resistance is effective, does not have cross resistance with at present existing bactericide.
Oxime bacterium ester (Trifloxystrobin) all has good activity to nearly all Mycophytes (Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti) disease such as powdery mildew, rust, Ying's rot, net blotch, downy mildew, rice blast etc.Except powdery mildew, leaf spot are had the special efficacy, rust, downy mildew, damping off, apple apple scab there is good activity.Oxime bacterium ester is mainly used in cauline leaf and handles, protection superior activity, and have certain therapeutic activity, and activity is not affected by environment, and using optimal period is spore germination and their early stage stage, but scab is all had activity each period.The activity of this compound is good, but unsatisfactory when hanging down rate of application sometimes.
Copper sulphate calcium is a kind ofly known crop to be had the compound of protective effect, is the bactericide of wide spectrum, and all fungoid and bacterial disease are had the good preventing effect.The big molecular complex of the copper ion that it is unique and calcium ion is guaranteed slow, the lasting release of copper ion.Copper, calcium ion have little fertile effect, can increase plant chlorophyll, strengthen photosynthesis, improve premunition, certain production-increasing function is arranged, but do not have systemic action.The activity of this compound is good, but unsatisfactory when hanging down rate of application sometimes.
Because environmental requirement and the economic requirement to bactericide continues to improve now, for example activity profile, toxicity, selectivity, rate of application, residue are formed and the requirement of favourable preparation feasibility, in addition owing to aspect drug resistance for example, may have problems, therefore, developing the new bactericide that is better than existing fungicide in some aspects is continuing of task.
The invention provides active compound combinations, it achieves the above object in some aspects at least.
Summary of the invention
The present invention seeks to provides a kind of fungicide active ingredient composition at above-mentioned weak point,
Found that described new active compound combinations has good antifungal and bacterium performance, said composition comprises formula (I) compound (2Z)-2-methoxyimino-2-[2-[[1-[3-(trifluoromethyl) phenyl] ethyleneimino] the oxygen methyl] phenyl] methyl acetate (oxime bacterium ester) and copper sulphate calcium compound.
Astoundingly, the bactericidal activity of active compound combinations of the present invention than the activity of each reactive compound add and obviously higher.In other words, there is synergistic effect unpredictable, necessary being, and is not only active augmenting.
When reactive compound was present in the active compound combinations of the present invention with specific weight ratio, synergistic effect was obvious especially.But the weight ratio of the reactive compound in the active compound combinations can change within the specific limits.
A kind of fungicide active ingredient composition of the present invention is to take following technical scheme to realize:
A kind of fungicide active ingredient composition is characterized in that: comprise a kind of formula (I) compound
With the copper sulphate calcium compound, the weight proportion of its Chinese style (I) reactive compound and copper sulphate calcium reactive compound is 1:1 to 1:100, and the ratio of preferred 1:5 to 1:50 exists, and the ratio that is more preferably 1:10 to 1:25 exists.
A kind of method of preventing and treating plant pathogen acts on pathogenic bacteria and/or its environment with the fungicide active ingredient composition, perhaps in plant, plant parts, seed, soil, zone, material or the space.
A kind of method of preventing and treating plant pathogen is used formula (I) compound and copper sulphate calcium compound simultaneously or is used respectively or sequential application.
A kind of preparation fungicide active ingredient method for compositions is mixed the reactive compound in the described active compound combinations with filler and/or surfactant.
The formulation of described fungicide active ingredient composition is suspending agent, plants clothing agent, wetting powder, water dispersible granules, microcapsule suspending agent, ZC, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
Described fungicide active ingredient composition, wherein the content of the active compound combinations of oxime bacterium ester and copper sulphate calcium accounts for the 5-90% of microbicide compositions.
Described fungicide active ingredient composition, wherein the content of the active compound combinations of oxime bacterium ester and copper sulphate calcium accounts for the 10-80% of microbicide compositions.
Described fungicide active ingredient composition is used for the purposes of control fungi and bacterium.
Described fungicide active ingredient composition is used for preventing and treating the purposes of fungi and bacterium on cereal, fruit, vegetables, the economic crops.
Above-claimed cpd oxime bacterium ester is commercially available.Formula (I) compound is known (for example referring to EP-A-460575)
From the structural formula of formula (I) reactive compound, obviously can find out this compound can E or the form of Z isomer exist.Therefore, the mixture that compound (I) can the different isomerization body or exist with the form of individual isomer.Preferred formula (I) compound exists with the E isomer.
Active compound combinations of the present invention has effective microbiocidal activity, and can be used for preventing and treating unwanted microorganisms in crop protection or material protection, as fungi and bacterium.
Active compound combinations of the present invention has extraordinary fungicide performance, and can be used to prevent and treat phytopathogenic fungi, as Plasmodiophoromycetes, Oomycete, Chytridiomycetes, connect and Gammaproteobacteria, Ascomycetes, Basidiomycetes, deuteromycetes etc.
Active compound combinations of the present invention has extraordinary bacterium performance extremely, and can be used to prevent and treat the plant malignant bacteria.As pseudomonadaceae, Rhizobiaceae, enterobacteriaceae, excellent Bacteriaceae and Streptomycetaceae.
As an example but unrestriced mode propose be included into above-mentioned big class some cause the pathogene of fungal disease and bacteriosis:
By the disease that the powdery mildew pathogene causes, pathogene such as Bu Shi Erysiphe bacterial classification;
Pathogene such as the glue Rust bacterial classification of the disease that is caused by the rust pathogene;
By the disease that Oomycete class pathogene causes, pathogene such as Peronospora bacterial classification;
By the disease that leaf spot and the sick disease pathogene of lobar atrophy cause, pathogene such as Alternaria bacterial classification;
Cause the disease that the harmful pathogene of root and stem disease causes, pathogene such as Fusarium bacterial classification;
Cause the pathogene of spadix and panicled spike disease, pathogene such as Alternaria bacterial classification;
The pathogene of the disease that is caused by smut, pathogene such as Ustilago kind;
Cause the pathogene of fruit rot, pathogene such as Penicillium bacterial classification;
Cause the pathogene of rotten and atrophy disease and seedling disease that kind of biography and soil pass, pathogene such as phytophthora belong to bacterial classification;
Cause the pathogene of wasting disease, pathogene such as chain sclerotinia sclerotiorum belong to;
Cause the pathogene of leaf, flower and fruit deformity, pathogene such as Exoascus bacterium bacterial classification;
Cause the pathogene of cancer disease, mycoceicidum and broom disease, pathogene such as Nectria bacterial classification;
Cause the pathogene of the degeneration disease of woody plant, pathogene such as Esca bacterial classification;
Cause the pathogene of flower and seed disease, pathogene such as Botrytis bacterial classification;
Since the pathogene of plant tuber disease, pathogene such as Rhizoctonia bacterial classification;
Active compound combinations of the present invention also demonstrates has very strong incentive action to plant.Therefore, they are applicable to that the inside of mobilizing plant defends to resist harmful microbe and attack.
In this article, plant excitation (induction of resistance) compound can be understood that such material, and system of defense that namely can stimulating plant makes can demonstrate significant resistance to these microorganisms when processed plant when inoculating harmful microorganism afterwards.
Among the present invention, harmful microorganism should be understood that fungi and the bacterium that plant is caused a disease.Therefore, compound of the present invention is used in and has carried out at protective plant in the certain hour after the processing of mentioned pathogen attack.A period of time that this protection reaches is generally from using reactive compound to handle preferred 1 to 7 day 1 to 10 day that begins to calculate.
The secondary infection that active compound combinations of the present invention is specially adapted to prevent and treat the rotting of mould and leaf spot, fruit and flower, storage disease and is caused by aspergillus fungi/Penicillium notatum etc.
Active agent combinations of the present invention is specially adapted to viticulture, fruit cultivation, crop-planting, vegetable growing and leguminous plant plantation.
Active agent combinations has good plant tolerance under the controlling plant diseases desired concn, this makes and can handle acrial part, in-vitro propagate strain, seed and the soil of plant.Active compound combinations of the present invention can also foliage applying or is used for seed dressing.
All plants and plant parts all can be handled according to the present invention.The implication of plant of the present invention should be understood that all plant and plant population, for example need and unwanted wild plant or crop plants (comprising the crop plants that nature exists).Crop plants can be by conventional breeding or optimum seeking method or the plant that obtains by biotechnology and genetic engineering method or the combination by described method; comprise genetically modified plants, also comprise the plant cultivars that is subjected to the protection of plant seedling power or is not subjected to its protection.The implication of plant parts should be understood that ground and underground position and the organ that plant is all, and for example bud, leaf, Hua Hegen, specifiable example have leaf, needle, stem, do, flower, fruit body, fruit, seed, root, stem tuber and rhizome.Plant parts also comprises harvested material, and asexual and sexual propagation thing, for example rice shoot, stem tuber, rhizome, cutting and seed.
The processing that reactive compound used according to the invention carries out plant and plant parts, directly carry out by conventional method, or realize by acting on its environment of living in, habitat or storage area, the for example immersion liquid of described conventional treatment method, spraying, evaporation, atomizing, broadcast sowing or smear, and, to breeding thing, especially seed, can also smear one or more layers.
Active compound combinations of the present invention can be converted into conventional formulation, for example suspending agent, plant clothing agent, wetting powder, water dispersible granules, microcapsule suspending agent, ZC, coated granule, extrude granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
A kind of bactericidal composition of the present invention comprises the active compound combinations of oxime bacterium ester and copper sulphate calcium.In the described microbicide compositions, the active compound combinations of oxime bacterium ester and copper sulphate calcium mixes with filler and/or surfactant.
In the described microbicide compositions of the present invention, the content that contains the active compound combinations of oxime bacterium ester and copper sulphate calcium accounts for the 5-90% of microbicide compositions, preferred 10-80%.
According to the present invention, term " filler " refer to can be with reactive compound combined or associating so that it is easier to be administered to the natural or synthetic organic or inorganic compound of object (for example plant, crop or careless class).Therefore, described filler is preferably inertia, and it is acceptable to should be agricultural at least.Described filler can be solid or liquid.
Operable nonactive media both can be that solid also can be liquid among the present invention, can be used as for example having that the solid media material uses: the phyteral powdery type (particle of soybean meal, starch, grain dust, wood powder, bark powder, sawdust, walnut shell powder, wheat bran, cellulose powder, coconut husk, corncob and tobacco stem for example, extract residue behind the plant essence etc.), paper, sawdust, pulverize synthesized polymer body, clay class (for example kaolin, bentonite, acid china clay etc.), the talcum powder class of synthetic resin etc.Silica class (for example diatomite, silica sand, mica, moisture silicic acid, calcium silicates), chemical fertilizer, the clay fertilizer of active carbon, natural mineral matter class (float stone, attapulgite and zeolite etc.), the inorganic mineral powder of firing diatomite, sand, plastics media etc. (for example polyethylene, polypropylene, polyvinylidene chloride etc.), potassium chloride, calcium carbonate, calcium phosphate etc., ammonium sulfate, ammonium phosphate, urea, greening ammonium etc., these materials can use separately or use with more than 2 kinds.
Can be used as can in following material, selecting of liquid media material use, water for example, alcohol type (methyl alcohol for example, ethanol, isopropyl alcohol, butanols, ethylene glycol etc.), ketone (acetone for example, methyl ethyl ketone, isobutyrone, cyclohexanone etc.), ethers (ether for example, dioxanes, methylcellulose, oxolane etc.), aliphatic hydrocarbon class (kerosene for example, the mineral wet goods), aromatic hydrocarbons class (benzene for example, toluene, dimethylbenzene, solvent naphtha, Fluhyzon, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbon, chlorobenzene, etc.), the halogenated hydrocarbon class, amide-type, the sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, the animal wet goods.
For making the emulsification of active ingredient compound; disperse; can dissolve; and/or the wetting surfactant that can use for example can enumerate fatty alcohol-polyoxyethylene ether; polyoxyethylene alkylaryl ether; the polyoxyethylene high-grade aliphatic ester; the phosphate of polyoxyethylene alcohol or phenol; the fatty acid ester of polyalcohol; the alkane aromatic sulfonic acid; the naphthalene sulfonic acids polymer; lignosulfonates; a dress copolymer of macromolecule comb shape; butyl naphthalene sulfonate; alkylaryl sulfonates; the alkyl sodium sulfosuccinate; grease; fatty alcohol and ethylene oxide condensate; polyacrylates such as alkyltaurate; protein hydrolysate.Suitable oligosaccharide thing or polymer are for example based on the combination of independent vinyl monomer, acrylic acid, EO and/or PO or itself and for example (polynary) alcohol or (polynary) amine.
For making active ingredient compound decentralized stabilization, adhering to and/or combination, for example can use adjuvants such as xanthans, aluminium-magnesium silicate, gelatin, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid (as cephalin and lecithin) and synthetic phospholipid, bentonite, sodium lignin sulfonate.
The optional spent glycol of antifreezing agent wherein, propane diols, glycerine, sorbierite.Deflocculant as the suspension product can use for example adjuvant of naphthalene sulfonic acids polymer, polymeric phosphate etc.
Can use silicone defoaming agent as defoamer.
Operable colouring agent, inorganic pigment for example is as iron oxide, titanium oxide and Prussian blue; And organic pigment/dyestuff: alizarin dyes, azo dyes and metal phthalocyanine dyestuff; And trace element, for example molysite, manganese salt, boron salt, mantoquita, cobalt salt, molybdenum salt and zinc salt.
Randomly, also can comprise other annexing ingredient, for example protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent, stabilizing agent, screening agent.
Described preparation of the present invention can mix described reactive compound by known way and prepare with conventional additives.Described conventional additives such as conventional extender and solvent or thinner, emulsifier, dispersant and/or adhesive or fixative, wetting agent, waterproofing agent, if desired, can also comprise drier and colouring agent, stabilizing agent, pigment, defoamer, preservative, thickener, water and other processing aid.
These compositions not only comprise and can be applicable to pending object immediately as spraying or dusting equipment by suitable device, are applied to the concentrated commercial composition that need dilute before the object but also be included in.
Of the present inventionly contain oxime bacterium ester and copper sulphate calcium active compound combinations can also be co-administered with other active component, for example be used for enlarging activity profile or preventing from forming resistance.Described other active component is fungicide, bactericide, attractant, insecticide, miticide, nematocide, growth regulator, weed killer herbicide, safener, fertilizer or semiochemical etc. for example.
As a further improvement on the present invention, the application of described disinfecting composition fungi and bacteriosis on the control crop.
Compound oxime bacterium ester and copper sulphate calcium can be used simultaneously, or use respectively, or sequential application, and the order during separate administration does not have influence usually to the result of control.
Active compound combinations of the present invention can itself be used, and uses with its dosage form or type of service prepared therefrom.By conventional methods it is used, for example water, spraying, atomizing, broadcast sowing, dust, and as the powder of handling dry seed, dry mixing powder, moist seed dressing, wet-mixing kind, slurries seed dressing, handle seed solution, handle seed water solube powder, handle the water solube powder of earth, or by the formation shell etc.
When using active compound combinations of the present invention or when containing active compound combinations bactericide of the present invention,
-when handling plant parts usually, the rate of application of active compound combinations is generally 0.1 to 10000g/ha, is preferably 10 to 1000g/ha;
During seed dressing, the rate of application of active compound combinations is 0.001 to 50g/kg seed, is preferably 0.01 to 10g/kg seed;
-for soil treatment: the rate of application of active compound combinations is generally 0.1-10000 g/ha, preferred 1-5000 g/ha.
Above-mentioned dosage only is general exemplary dose, and those skilled in the art can especially adjust rate of application according to the character of pending plant or crop and the seriousness of germ according to actual conditions and needs during actual using.
A kind of fungicide active ingredient composition of the present invention, comprise formula (I) compound (2Z)-2-methoxyimino-2-[2-[[1-[3-(trifluoromethyl) phenyl] ethyleneimino] the oxygen methyl] phenyl] methyl acetate (oxime bacterium ester) and copper sulphate calcium compound, have synergistic function, the bactericidal activity of active compound combinations of the present invention than the activity of each reactive compound add and obviously higher.In other words, there is synergistic effect unpredictable, necessary being, and is not only active augmenting.
When reactive compound was present in the active compound combinations of the present invention with specific weight ratio, synergistic effect was obvious especially.
The good bactericidal property of active compound combinations of the present invention can illustrate by following examples.Though independent reactive compound activity aspect its bactericidal action a little less than, active compound combinations demonstrate above each self-applying simply add and activity.
Embodiment
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is a kind of mode effectively and efficiently that exploitation at present and development novel pesticide and control agricultural go up the resistance germ.The agricultural chemicals of different cultivars shows three kinds of type of action: summation action, synergistic effect and antagonism after mixing usually.But be specially which kind of effect, unpredictable, have only by a large amount of experiments and just can know.Compound synergic is well filled a prescription, owing to obviously improved actual control efficiency, reduced the usage amount of agricultural chemicals, thereby delayed the drug-fast generation speed of germ widely, and be the important means of integrated control disease.
FORMULATION EXAMPLE:
Embodiment 1 2% oxime bacterium ester+10% copper sulphate calcium wetting powder
Oxime bacterium ester 2%
Copper sulphate calcium 10%
Lauryl sodium sulfate 10%
Sodium lignin sulfonate 5%
White carbon 10%
Kaolin complements to 100%
Ratio composition in prescription such as active component, various auxiliary agent and filler is mixed, after ultrafine crusher is pulverized, namely obtain 2% oxime bacterium ester+10% copper sulphate calcium wetting powder.
Embodiment 2 1% oxime bacterium esters+50% copper sulphate calcium wetting powder
Oxime bacterium ester 1%
Copper sulphate calcium 50%
Calcium dodecyl benzene sulfonate 1%
Sodium lignin sulfonate 2%
Sucrose complements to 100%
Ratio composition in prescription such as active component, various auxiliary agent and filler is mixed, after ultrafine crusher is pulverized, namely obtain 1% oxime bacterium ester+50% copper sulphate calcium wetting powder.
Embodiment 3 1% oxime bacterium esters+4% copper sulphate calcium missible oil
Oxime bacterium ester 1%
Copper sulphate calcium 4%
Ethoxylated castor oil 5%
Calcium dodecyl benzene sulfonate 3%
Dimethyl sulfoxide (DMSO) complements to 100%
Mentioned component is proportionally prepared, and stirring obtains the phase of homogeneous.
Embodiment 4 5% oxime bacterium esters+50% copper sulphate calcium wetting powder
Oxime bacterium ester 5%
Copper sulphate calcium 50%
Lauryl sodium sulfate 10%
Sodium lignin sulfonate 5%
White carbon 10%
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 5 2% oxime bacterium esters+50% copper sulphate calcium water dispersible granules
Oxime bacterium ester 2%
Copper sulphate calcium 50%
MODIFIED LIGNOSULPHONATE 5%
Lauryl sodium sulfate 5%
Urea 5%
Kaolin complements to 100%
Oxime bacterium ester active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, be ground into wetting powder through air-flow; Adding copper sulphate calcium again mixes; Add a certain amount of water mixing extruding again and make material.Obtain 2% oxime bacterium ester+50% copper sulphate calcium water dispersible granules after the drying screening.
Embodiment 6 0.5% oxime bacterium esters+50% copper sulphate calcium suspension emulsion
Oil phase:
Oxime bacterium ester 0.5%
Methyl oleate 10%
Ethoxylated castor oil 5%
Water:
Copper sulphate calcium 50%
The sodium salt 1% of the naphthalene sulfonic acids-formaldehyde condensation products of sulfonation
Water complements to 100%
Oxime bacterium ester is dissolved in the methyl oleate, adds ethoxylated castor oil and obtain oil phase; According to prescription with the sodium salt of the naphthalene sulfonic acids-formaldehyde condensation products of copper sulphate calcium, sulfonation, water through grind and/or high speed shear after obtain the aqueous suspension agent of copper sulphate calcium; Under agitation oil phase is added water and obtain suspension emulsion.
Embodiment 7 10% oxime bacterium esters+10% copper sulphate calcium wetting powder
Oxime bacterium ester 10%
Copper sulphate calcium 10%
Sodium lignin sulfonate 1%
NaLS 2%
The silicic acid 1% of high degree of dispersion
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 8 40% oxime bacterium esters+50% copper sulphate calcium coated granule
Oxime bacterium ester 40%
Copper sulphate calcium 50%
Polyethylene glycol 3%
The silicic acid 1% of high degree of dispersion
Calcium carbonate complements to 100%
In blender, levigate active component evenly is applied to by on the wetting carrier of polyethylene glycol.Can obtain dustless coated granule in this way.
Embodiment 9 10% oxime bacterium esters+50% copper sulphate calcium wetting powder
Oxime bacterium ester 10%
Copper sulphate calcium 50%
Lauryl sodium sulfate 1%
Sodium lignin sulfonate 1%
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 10 20% oxime bacterium esters+60% copper sulphate calcium is extruded granule
Oxime bacterium ester 20%
Copper sulphate calcium
60%
Sodium lignin sulfonate 4%
Carboxymethyl cellulose 2%
Kaolin complements to 100%
Active component is mixed with auxiliary agent and grind the mixture water-wet.This mixture is extruded, dry in air stream then.
Embodiment 11 1% oxime bacterium esters++ 20% copper sulphate calcium kind clothing agent
Oxime bacterium ester 1%
Copper sulphate calcium 20%
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium 10%
MODIFIED LIGNOSULPHONATE 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
PVP-K30 1%
Water complements to 100%
With above-mentioned each component mix in proportion through grind and/or high speed shear after obtain kind of a clothing agent.
Embodiment 12 5% oxime bacterium esters+10% copper sulphate calcium ZC
Atlox 4913 4%
Citric acid 0.05%
Catalyzer 0.1%
Water 13%
Copper sulphate calcium 10%
PAPI 1.35%
Solvesso 200 10%
Atlox4913 16%
Dispersant LFH 0.3%
Defoamer 0.16%
Urea 8.4%
Oxime bacterium ester 5%
Water complements to 100%
The oil phase adding that PAPI, oxime bacterium ester, Solvesso 100 are formed contains in the aqueous solution of Atlox4913, forms emulsion.Heat then and be incubated under 50oC and added catalyst reaction 2 hours.Obtain the microcapsules of oxime bacterium ester after the cooling.
Atlox 4913, dispersant LFH, and defoamer, urea, copper sulphate calcium and water mix in proportion, obtain evenly obtaining suspending agent after grinding and/or high speed shear.
The oxime bacterium ester micro capsule agent that obtains is added in the suspending agent of copper sulphate calcium, and stirring obtains 5% oxime bacterium ester+10% copper sulphate calcium ZC.
Embodiment 13 5% oxime bacterium esters+30% copper sulphate calcium suspension emulsion
Oxime bacterium ester 5%
Copper sulphate calcium 30%
Solvesso 200 10%
Ethoxylated castor oil 4%
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium 5%
MODIFIED LIGNOSULPHONATE 5%
Xanthans 1%
Bentonite 1%
Glycerine 5%
Water complements to 100%
Oxime bacterium ester is dissolved among the Solvesso 200, adds ethoxylated castor oil, obtain the oil phase of oxime bacterium ester;
Fatty alcohol-polyoxyethylene ether sulfosuccinic acid monoesters disodium, MODIFIED LIGNOSULPHONATE, copper sulphate calcium and water are mixed in proportion, after grinding and/or high speed shear, obtain evenly obtaining the suspending agent of copper sulphate calcium.
The oil phase that will contain oxime bacterium ester joins the aqueous suspension agent of sulfur acid copper calcium, obtains suspension emulsion.
Embodiment 14 5% oxime bacterium esters+5% copper sulphate calcium missible oil
Oxime bacterium ester 5%
Copper sulphate calcium 5%
Ethoxylated castor oil 5%
Calcium dodecyl benzene sulfonate 3%
Solvesso100 complements to 100%
Above-mentioned each component is mixed, be stirred to and obtain transparent homogeneous phase.
Embodiment 15 20% oxime bacterium esters+30% copper sulphate calcium water dispersible granules
Oxime bacterium ester 20%
Copper sulphate calcium 30%
MODIFIED LIGNOSULPHONATE 5%
Lauryl sodium sulfate 5%
Urea 5%
Kaolin complements to 100%
Oxime bacterium ester, copper sulphate calcium active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, be ground into wetting powder through air-flow; Add a certain amount of water mixing extruding again and make material.Obtain 20% oxime bacterium ester+30% copper sulphate calcium water dispersible granules after the drying screening.
Embodiment 16 8% oxime bacterium esters+30% copper sulphate calcium wetting powder
Oxime bacterium ester 8%
Copper sulphate calcium 30%
Lauryl sodium sulfate 1%
Sodium lignin sulfonate 1%
Kaolin complements to 100%
Said components is mixed in proportion, and grind, pulverize, be prepared into wetting powder.
Embodiment 17 10% oxime bacterium esters+60% copper sulphate calcium
Oxime bacterium ester 10%
Copper sulphate calcium 60%
Oxime bacterium ester, copper sulphate calcium are proportionally mixed.
Embodiment 18 3% oxime bacterium esters+47% copper sulphate calcium
Oxime bacterium ester 3%
Copper sulphate calcium 47%
Proportioning among the above embodiment is the weight per distribution ratio.
The biological test example
When the effect of active compound combinations surpasses the summation of the effect when each reactive compound is used separately, there is synergistic function.The predictive role of the particular combination of two kinds of reactive compounds can use so-called " Colby formula " (referring to S.R. Colby, " Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) following calculating: if
X be when use consumption as mg/ha or concentration the activity during as the reactive compound A of mppm;
Y be when use consumption as ng/ha or concentration the activity during as the reactive compound B of nppm, be expressed as the percentage that accounts for untreated control;
E be when use consumption as m and n g/ha or concentration the activity during as the reactive compound A of m and n ppm and B,
So
If the activity of actual observation (O) is greater than expection active (E), so said composition super add and, namely have synergistic effect.
Following biological test example is in order to illustrate the present invention.But the present invention is not limited to these embodiment.
The mould test of epidemic disease (tomato)/protectiveness
Solvent: the acetone of 24.5 weight portions
24.5 the dimethylacetylamide of weight portion
Emulsifier: 1 weight portion alkylaryl polyglycol ether
For preparing suitable active agent preparations, with the reactive compound of 1 weight portion or solvent and the emulsifier of active compound combinations and above-mentioned amount, and the required concentration of this dope of dilute with water, perhaps the preparation of commercially available reactive compound or preparation and the water of active compound combinations are diluted with water to required concentration.
Active for the test protection, spray rice shoot with active agent preparations with affiliated rate of application.After spraying layer exsiccation, inoculate this plant with the water spore suspension of phytophthora infestans (Phytophthora infestans).Plant is placed on about 20 then
oC, relative air humidity are in 100% the culturing room.
Inoculating back 3 days measures.At this moment, 0% refers to equal the drug effect of control group, and 100% refers to not observe infection.
The mould test of epidemic disease (tomato)/protectiveness
The activity that last table clearly shows active compound combinations of the present invention is greater than the activity that calculates, and namely there are synergistic effect in oxime bacterium ester and copper sulphate calcium in the scope of 1:1 to 1:100.
Claims (14)
1. a fungicide active ingredient composition is characterized in that: comprise a kind of formula (I) compound
(formula I)
With the copper sulphate calcium compound, the weight proportion of its Chinese style (I) reactive compound and copper sulphate calcium reactive compound is 1:1 to 1:100.
2. fungicide active ingredient composition according to claim 1, it is characterized in that: in active compound combinations, the weight ratio of formula (I) compound and copper sulphate calcium is 1:5 to 1:50.
3. fungicide active ingredient composition according to claim 1 and 2 is characterized in that, in active compound combinations, the weight ratio of formula (I) compound and copper sulphate calcium is 1:10 to 1:25.
4. a method of preventing and treating plant pathogen is characterized in that, the fungicide active ingredient composition in the claim 1 is acted on pathogenic bacteria and/or its environment, perhaps in plant, plant parts, seed, soil, zone, material or the space.
5. the described method of claim 4, it is characterized in that: the formula of claim 1 (I) compound and copper sulphate calcium compound are used simultaneously or are used respectively or sequential application.
6. a fungicide active ingredient composition is characterized in that: comprise the described active compound combinations of claim 1.
7. one kind prepares the fungicide active ingredient method for compositions, it is characterized in that the reactive compound in the active compound combinations described in the claim 1 is mixed with filler and/or surfactant.
8. according to the fungicide active ingredient composition of claim 6, it is characterized in that the formulation of described bactericidal composition is suspending agent, plants clothing agent, wetting powder, water dispersible granules, microcapsule suspending agent, ZC, coated granule, extrudes granule, missible oil, microemulsion, aqueous emulsion, effervescent tablet.
9. according to the fungicide active ingredient composition of claim 6, it is characterized in that: the content of the active compound combinations of oxime bacterium ester and copper sulphate calcium accounts for the 5-90% of microbicide compositions.
10. according to the fungicide active ingredient composition of claim 9, it is characterized in that: the content of the active compound combinations of oxime bacterium ester and copper sulphate calcium accounts for the 10-80% of microbicide compositions.
11. be used for the purposes of control fungi and bacterium according to the fungicide active ingredient composition of claim 1.
12. be used for the purposes of control fungi and bacterium according to the fungicide active ingredient composition of claim 6.
13. be used for preventing and treating the purposes of fungi and bacterium on cereal, fruit, vegetables, the economic crops according to the fungicide active ingredient composition of claim 1.
14. be used for preventing and treating the purposes of fungi and bacterium on cereal, fruit, vegetables, the economic crops according to the fungicide active ingredient composition of claim 6.
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| CN104365669A (en) * | 2014-10-30 | 2015-02-25 | 柳州市惠农化工有限公司 | Dinotefuran and copper calcium sulphate suspension emulsion and application thereof |
| CN104604938A (en) * | 2013-11-04 | 2015-05-13 | 龙灯农业化工国际有限公司 | Fungicidal composition and the use thereof |
| CN104663711A (en) * | 2015-02-16 | 2015-06-03 | 中化宁波（集团）有限公司 | Plant bactericidal composition and preparation method thereof |
| CN105580805A (en) * | 2014-11-16 | 2016-05-18 | 陕西美邦农药有限公司 | Pesticide composition containing copper (succinate + glutarate + adipate) |
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| CN101697729A (en) * | 2009-11-03 | 2010-04-28 | 成都皇牌作物科学有限公司 | Disinfectant compound containing cyproconazole |
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| CN102669181A (en) * | 2012-06-13 | 2012-09-19 | 江苏龙灯化学有限公司 | Sterilization composition containing captan and copper calcium sulfate and application of sterilization composition |
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| CN101697729A (en) * | 2009-11-03 | 2010-04-28 | 成都皇牌作物科学有限公司 | Disinfectant compound containing cyproconazole |
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| CN104604938A (en) * | 2013-11-04 | 2015-05-13 | 龙灯农业化工国际有限公司 | Fungicidal composition and the use thereof |
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| CN105580805A (en) * | 2014-11-16 | 2016-05-18 | 陕西美邦农药有限公司 | Pesticide composition containing copper (succinate + glutarate + adipate) |
| CN104663711A (en) * | 2015-02-16 | 2015-06-03 | 中化宁波（集团）有限公司 | Plant bactericidal composition and preparation method thereof |
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| CN103329937B (en) | 2015-07-15 |
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