CN105961409A - Sterilization composition containing Bixafen and Tiadinil and application thereof - Google Patents

Sterilization composition containing Bixafen and Tiadinil and application thereof Download PDF

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Publication number
CN105961409A
CN105961409A CN201610356431.0A CN201610356431A CN105961409A CN 105961409 A CN105961409 A CN 105961409A CN 201610356431 A CN201610356431 A CN 201610356431A CN 105961409 A CN105961409 A CN 105961409A
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Prior art keywords
tiadinil
bacterium amine
pyrrole bacterium
biphenyl pyrrole
bactericidal composition
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Inventor
白杰
郭崇友
张宝俊
邢刚
杨琴
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Nanjing Huazhou Pharmaceutical Co Ltd
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Nanjing Huazhou Pharmaceutical Co Ltd
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Priority to CN201610356431.0A priority Critical patent/CN105961409A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/82Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a sterilization composition containing Bixafen and Tiadinil and application thereof. The sterilization composition comprises the following main effective components: Bixafen and Tiadinil, wherein the mass ratio of Bixafen to Tiadinil is (1-70) to (1-50). The sterilization composition can be applied to the prevention and the control of diseases of cereals, fruit trees and vegetables and has a relatively high synergistic interaction effect, the pesticide resistance of germs is overcome and delayed, the sterilization speed is high, the lasting period is long, the application cost is lowered, and the prevention and control effects are obviously superior to the prevention and control effects of a single preparation. The sterilization composition can be used for preventing and controlling fungoid on crops and particularly used for preventing and controlling fungal diseases such as leaf spot disease, brown leaf rust, downy mildew, rice blast and damping off, and the effect is superior to that of the single preparation.

Description

A kind of containing biphenyl pyrrole bacterium amine and the bactericidal composition of tiadinil and application
Technical field:
The present invention relates to a kind of bactericidal composition and application thereof, especially one is main with biphenyl pyrrole bacterium amine and tiadinil The bactericidal composition of active component and application thereof.
Background technology
Biphenyl pyrrole bacterium amine (Bixafen), chemical formula: C18H12Cl2F3N3O, chemical name: N-(3 ', 4 '-two chloro-5- Fluorine hexichol-2-base)-3-(difluoromethyl)-1-methylpyrazole-4-Methanamide.Structural formula:
Biphenyl pyrrole bacterium amine is pyrazoles antibacterial, is that the interior absorption that a kind of novel wide spectrum, protection and therapeutic activity have concurrently is killed Microbial inoculum.
Tiadinil (Tiadinil), molecular formula: C11H10ClN3OS, chemical name: 3'-chloro-4,4'-dimethyl-1,2,3- Thiadiazoles-5-formailide.Structural formula:
Tiadinil is the systemic fungicide of a kind of novelty, is transmitted to rapidly other positions by root absorption.Medicament is originally Body is poor to the inhibitory activity of pathogenic bacteria, by stoping pathogenic bacteria mycelia to invade neighbouring healthy cell, and can induce the disease-resistant base of generation Cause.Using in suitable water, the lasting period is long, to leaf blast is sick and fringe rice blast has preferable prevention effect.
The difficulty of prevention and cure of phytopathogen is increasing at present, on the one hand, along with the change of pattern of farming, melon fruits and vegetables etc. Industrial crops cultivated area progressively expands, and disease occurrence degree, generation quantity all increase, and in preventing and treating, difficulty strengthens; On the other hand, the resistance of pathogen rises under lasting medicament selection pressure year by year, and the prevention effect of single dose is had a greatly reduced quality, Control of plant disease is faced with significant challenge.
Summary of the invention:
It is an object of the invention to provide a kind of applied widely, low cost for above-mentioned technical problem, effective containing biphenyl Pyrrole bacterium amine and the plant bactericidal composition of tiadinil.
It is a still further object of the present invention to provide this bactericidal composition and cause the application on fungal disease at preventing and treating plant epiphyte, Especially in the purposes prevented and treated on the fungal diseases such as leaf spot, leaf rust, downy mildew, rice blast, damping-off.
It is an object of the invention to be achieved through the following technical solutions:
A kind of containing biphenyl pyrrole bacterium amine and the bactericidal composition of tiadinil, this bactericidal composition is with biphenyl pyrrole bacterium amine and thiophene acyl bacterium Amine is principle active component, and wherein biphenyl pyrrole bacterium amine is 1~70:1~50 with the mass ratio of tiadinil, wherein sterilization group In compound, active ingredient is present in compositions with enhancing effective amount.
Described bactericidal composition, wherein biphenyl pyrrole bacterium amine is preferably 1~50:1~30 with the mass ratio of tiadinil, enters One step is preferably 1~30:1~10, the most preferably 2.5~20:4~10.Biphenyl pyrrole bacterium amine is excellent with tiadinil Select the quality proportioning to be: 70:1,50:1,30:1,20:1,10:1,5:1,2.5:1,1:1,1: 2,1:4,1:6,1:10,1:20,1:30,1:50.
In the compositions of the present invention, the weight/mass percentage composition accounting for compositions both biphenyl pyrrole bacterium amine and tiadinil is 2~80%.Preferably 5~70%.
Described bactericidal composition, wherein with biphenyl pyrrole bacterium amine and tiadinil for principle active component and known auxiliary agent and Excipient is re-dubbed on pesticide any one dosage form allowed.Auxiliary agent known to these, excipient have dispersant, diffusant, Defoamer, wetting agent, disintegrating agent etc., can use calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, benzylphenol Polyoxyethylene ether, phenethyl phenol polyethenoxy ether, fatty alcohol-polyoxyethylene ether and similar products, aliphatic amine polyoxyethylene Ether, fatty acid ethylene oxide addition product, polyoxyethylene polyoxy propylene block compound, castor oil polyoxyethylene ether, nonyl Phenol polyethenoxy ether, TWEEN Series, fatty alcohol-polyoxyethylene ether, Polyethylene Glycol series, Sulfonates, carboxylate, sulfur Hydrochlorate, phosphate, phosphite, lignosulfonates, xanthan gum, phenol formaldehyde condensate, ammonium salt, quaternary etc. In one or more combinations, excipient includes that Ketohexamethylene, dimethylbenzene, various solvent naphtha, water, antifreezing agent are (such as the third two Alcohol), deionized water etc..Above auxiliary agent, excipient and other adjuvant can be alone or and use.
Described bactericidal composition, its dosage form is cream, wettable powder, suspending agent, aqueous emulsion or water dispersion granule.
The application on preparation preventing and treating fungal diseases of plants medicine of the above-mentioned bactericidal composition.Especially preventing and treating Cereal, Application in terms of fruit tree, vegetable crop disease has significant effect.
Above-mentioned application, described fungal diseases of plants is in leaf spot, leaf rust, downy mildew, rice blast, damping-off At least one.
The feature of bactericidal composition of the present invention:
1, the biphenyl pyrrole bacterium amine used by the present invention and tiadinil, the mechanism of action is different, and mutual mixture will not produce low touching, Can Synergistic, reduce dosage, reduce cost.
2, the present composition scope of application increases, it is adaptable to preventing and treating Cereal, fruit tree, the refractory fungal disease of vegetable, Particularly prevent and treat leaf spot, leaf rust, downy mildew, rice blast, damping-off etc. and all have significant effect.The present invention sterilizes Compositions has good prevention effect to ascomycetes, basidiomycetes, Fungi Imperfecti and Oomycete fungal disease;And suppress insect Or fungus or the antibacterial drug-fast generation to unitary agent (biphenyl pyrrole bacterium amine and tiadinil are arbitrary).The present invention sterilizes Compositions can produce higher synergistic function, and the consumption of the independent reactive compound of amount ratio of this mixture is significantly Reducing, i.e. the activity of mixture is more than the activity of independent component.
Compared with prior art beneficial effects of the present invention: (1), compared with single dose, said composition antagonism fungal disease is such as The fungal diseases such as leaf spot, leaf rust, downy mildew, rice blast, damping-off have obvious synergistic function, overcome and prolong Having delayed Drug resistance, expanding prevention is composed, hence it is evident that improve prevention effect;(2) preventing and treating recruitment, drug cost are reduced;(3) Alternative routine and the pesticide being easily generated resistance;(4) compared with single dose, produce and use cost reduces;(5) suppression is true The drug-fast generation of bacterium, its effect uses apparently higher than its single dose.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, and in embodiment, the preparation method of dosage form is conventional method, " % " of the present invention is mass percent.
Indoor biometrics is tested:
In indoor employing mycelial growth rate method, measure the different agents EC to bacterial strain50Value, uses co-toxicity coefficient calculating side Method, calculates the co-toxicity coefficient (CTC) of mixture, determines the building performance of mixture, and circular is as follows:
In mixture, a certain single dose (is generally selected EC as standard agent50Junior), calculate:
Single dose toxicity index=standard agent EC50/ certain single dose EC50×100
Toxicity index × A the single dose of theoretical toxicity index=A single dose in mixture the toxicity index of proportion+B single dose × B single dose proportion in mixture
The EC of actual measurement toxicity index=standard single dose50The EC of value/mixture50Value × 100
Co-toxicity coefficient=actual measurement toxicity index/theory toxicity index × 100
When co-toxicity coefficient classification: CTC is more than 120, mixture has synergetic, is antagonism when CTC is less than 80, CTC It it is summation action between 80-120.
According to effective ingredient biphenyl pyrrole bacterium amine (A): tiadinil (B) quality proportioning is: 80:1,70:1,50: 1,30:1,20:1,10:1,5:1,2.5:1,1:1,1:2,1:4,1:6,1:10,1:20,1: 30,1:50,1:60,1:70 test, and measure it to rice blast (PyriculariaoryaeCav.) Co-toxicity coefficient.
Table 1: biphenyl pyrrole bacterium amine+tiadinil different ratio indoor biometrics result to rice blast
Medicament Virulence regression equation EC50(mg/L) Co-toxicity coefficient
10% biphenyl pyrrole bacterium amine WP Y=4.624+2.054X 1.524 -
20% tiadinil SC Y=2.395+3.623X 5.236 -
A:B=80:1 Y=3.526+2.203X 4.666 113.20
A:B=70:1 Y=3.206+3.202X 3.634 145.52
A:B=50:1 Y=2.838+4.221X 3.253 163.23
A:B=30:1 Y=3.463+3.562X 2.700 198.45
A:B=20:1 Y=4.359+1.241X 3.283 165.08
A:B=10:1 Y=2.827+4.250X 3.246 172.42
A:B=5:1 Y=4.091+1.754X 3.297 180.08
A:B=2.5:1 Y=3.701+2.005X 4.444 147.75
A:B=1:1 Y=2.176+3.633X 5.988 135.45
A:B=1:2 Y=3.215+2.547X 5.020 197.78
A:B=1:4 Y=4.763+0.258X 8.294 145.85
A:B=1:6 Y=3.437+1.579X 9.775 136.53
A:B=1:10 Y=2.384+2.653X 9.686 152.06
A:B=1:20 Y=2.782+2.021X 12.516 128.79
A:B=1:30 Y=0.572+4.110X 11.951 139.56
A:B=1:50 Y=2.852+2.142X 10.069 170.52
A:B=1:60 Y=2.172+2.302X 16.926 102.20
A:B=1:70 Y=3.564+1.214X 15.237 114.15
Field control effectiveness test:
The pesticidal preparations preventing and treating rice blast test prepared with above-described embodiment.
1, test processes: this test medicine consumption sets three concentration for the treatment of respectively according to the difference of each composition, compares medicine Agent is pesticide single dose 10% biphenyl pyrrole bacterium amine WP and 20% tiadinil SC and blank clean water experiment respectively.
2, each plot area of test method is 66.7m2, it is repeated 3 times;Investigation drug effect after investigating before dispenser and preventing and treating Method is: randomization 5 point in test treatment region, carries out severity Scaling according to country's field test relevant criterion, meter Calculate preventive effect.Result of the test is shown in Table 2:
Table 2 field test effect
Being shown by indoor biometrics and field efficacy result, biphenyl pyrrole bacterium amine and tiadinil compositions have the most collaborative Potentiation, the prevention effect of compositions is excellent, and prevention effect is all better than single dose kind, has application in agricultural is applied It is worth.
Two kinds of reactive compounds can be processed into any one dosage form of permission, illustrates that two kinds have with specific embodiment below The preparation that effect composition is processed into, but the preparation that these two kinds of active component can be processed is not limited only to set forth below.
Embodiment 1:15% biphenyl pyrrole bacterium amine tiadinil wettable powder (1:2)
By biphenyl pyrrole bacterium amine 5g, tiadinil 10g, detergent LS (to methoxyl group fatty acid amido benzene sulfonic acid sodium salt) 2g, Dispersing agent NNO (sodium methylene bis-naphthalene sulfonate) 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out air-flow powder Broken, preparing effective ingredient mass percent is 15% biphenyl pyrrole bacterium amine tiadinil wettable powder.
Embodiment 2:15% biphenyl pyrrole bacterium amine tiadinil wettable powder (1:4)
By biphenyl pyrrole bacterium amine 3g, tiadinil 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient mass percent is 15% biphenyl pyrrole bacterium amine thiophene Acyl bacterium amine wettable powder.
Embodiment 3:14% biphenyl pyrrole bacterium amine tiadinil wettable powder (1:6)
By biphenyl pyrrole bacterium amine 2g, tiadinil 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient mass percent is 14% biphenyl pyrrole bacterium amine thiophene Acyl bacterium amine wettable powder.
Embodiment 4:20% biphenyl pyrrole bacterium amine tiadinil suspending agent (1:1)
Weigh 10g biphenyl pyrrole bacterium amine, 10g tiadinil, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate thereof 4g, xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand Making effective Ingredient percent under the effect of grinding machine is 20% biphenyl pyrrole bacterium amine tiadinil suspending agent.
Embodiment 5:55% biphenyl pyrrole bacterium amine tiadinil aqueous emulsion (1:10)
Weigh 5g biphenyl pyrrole bacterium amine, 50g tiadinil, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, Alkylphenol polyoxyethylene 1g, 150# solvent naphtha 13g, add water to 100g.Above raw material is prepared aqueous emulsion routinely Method puts into the mixing of mixing kettle high speed, and making effective Ingredient percent is 55% biphenyl pyrrole bacterium amine tiadinil water Emulsion.
Embodiment 6:42% biphenyl pyrrole bacterium amine tiadinil cream (1:20)
Weigh 2g biphenyl pyrrole bacterium amine, 40g tiadinil, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is formed with Effect Ingredient percent is 42% biphenyl pyrrole bacterium amine tiadinil cream.
Embodiment 7:70% biphenyl pyrrole bacterium amine tiadinil cream (2.5:1)
Weigh 50g biphenyl pyrrole bacterium amine, 20g tiadinil, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g, castor oil polyoxyethylene ether 2g, 150# solvent naphtha to 100g.The method that above raw material is prepared cream routinely is thrown Entering in mixing kettle and mix, making effective Ingredient percent is 70% biphenyl pyrrole bacterium amine tiadinil cream.
Embodiment 8:18% biphenyl pyrrole bacterium amine tiadinil water dispersion granule (5:1)
Weigh 15g biphenyl pyrrole bacterium amine, 3g tiadinil, wooden sodium sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, Borax 2g, kieselguhr complements to 100g, is made by water dispersible granular agent method by above raw material Effective ingredient mass percent is 17% biphenyl pyrrole bacterium amine tiadinil water dispersion granule.
Embodiment 9:11% biphenyl pyrrole bacterium amine tiadinil cream (10:1)
Weigh 10g biphenyl pyrrole bacterium amine, 1g tiadinil, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is formed with Effect Ingredient percent is 11% biphenyl pyrrole bacterium amine tiadinil cream.
Embodiment 10:31.5% biphenyl pyrrole bacterium amine tiadinil microemulsion (20:1)
Weigh 30g biphenyl pyrrole bacterium amine, 1.5g tiadinil, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether Phosphate ester 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.To be the most former Material is prepared the method for microemulsion routinely and is put into mixing in mixing kettle, and making effective Ingredient percent is 31.5% biphenyl Pyrrole bacterium amine tiadinil microemulsion.
Embodiment 11:31% biphenyl pyrrole bacterium amine tiadinil cream (30:1)
Weigh 30g biphenyl pyrrole bacterium amine, 1g tiadinil, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is formed with Effect Ingredient percent is 31% biphenyl pyrrole bacterium amine tiadinil cream.
Embodiment 12:51% biphenyl pyrrole bacterium amine tiadinil suspending agent (50:1)
Weigh 50g biphenyl pyrrole bacterium amine, 1g tiadinil, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate thereof 4g, xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand Making effective Ingredient percent under the effect of grinding machine is 51% biphenyl pyrrole bacterium amine tiadinil suspending agent.
Embodiment 13:32% biphenyl pyrrole bacterium amine tiadinil microemulsion (1:15)
Weigh 2g biphenyl pyrrole bacterium amine, 30g tiadinil, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether Phosphate ester 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.To be the most former Material is prepared the method for microemulsion routinely and is put into mixing in mixing kettle, and making effective Ingredient percent is 32% biphenyl pyrrole Bacterium amine tiadinil microemulsion.
Embodiment 14:6% biphenyl pyrrole bacterium amine tiadinil aqueous emulsion (1:5)
Weigh 1g biphenyl pyrrole bacterium amine, 5g tiadinil, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, Alkylphenol polyoxyethylene 1g, 150# solvent naphtha 13g, add water to 100g.Above raw material is prepared aqueous emulsion routinely Method puts into the mixing of mixing kettle high speed, and making effective Ingredient percent is 6% biphenyl pyrrole bacterium amine tiadinil water and milk Agent.
Embodiment 15:62% biphenyl pyrrole bacterium amine tiadinil microemulsion (1:30)
Weigh 2g biphenyl pyrrole bacterium amine, 60g tiadinil, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether Phosphate ester 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.To be the most former Material is prepared the method for microemulsion routinely and is put into mixing in mixing kettle, and making effective Ingredient percent is 62% biphenyl pyrrole Bacterium amine tiadinil microemulsion.
Embodiment 16:51% biphenyl pyrrole bacterium amine tiadinil suspending agent (1:50)
Weigh 1g biphenyl pyrrole bacterium amine, 50g tiadinil, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate thereof 4g, xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand Making effective Ingredient percent under the effect of grinding machine is 51% biphenyl pyrrole bacterium amine tiadinil suspending agent.
Embodiment 17:7% biphenyl pyrrole bacterium amine tiadinil water dispersion granule (1:2.5)
Weigh 2g biphenyl pyrrole bacterium amine, 5g tiadinil, wooden sodium sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, Borax 2g, white carbon 3g, kieselguhr complement to 100g, above raw material are pressed water dispersible granular It is 7% biphenyl pyrrole bacterium amine tiadinil water dispersion granule that agent method makes effective Ingredient percent.

Claims (10)

1. one kind contains biphenyl pyrrole bacterium amine and the bactericidal composition of tiadinil, it is characterised in that this bactericidal composition is with biphenyl Pyrrole bacterium amine and tiadinil are principle active component, and wherein biphenyl pyrrole bacterium amine is 1~70:1~50 with the mass ratio of tiadinil.
Bactericidal composition the most according to claim 1, it is characterised in that described biphenyl pyrrole bacterium amine and tiadinil Mass ratio is 1~50:1~30.
Bactericidal composition the most according to claim 2, it is characterised in that described biphenyl pyrrole bacterium amine and tiadinil Mass ratio is 1~30:1~10.
Bactericidal composition the most according to claim 3, it is characterised in that described biphenyl pyrrole bacterium amine and tiadinil Mass ratio is 2.5~30:1~10.
Bactericidal composition the most according to claim 1, it is characterised in that described biphenyl pyrrole bacterium amine and tiadinil The two weight/mass percentage composition accounting for compositions is 2-80%.
Bactericidal composition the most according to claim 5, it is characterised in that described biphenyl pyrrole bacterium amine and tiadinil The two weight/mass percentage composition accounting for compositions is 5-70%.
Bactericidal composition the most according to claim 1, it is characterised in that based on biphenyl pyrrole bacterium amine and tiadinil Effective ingredient and insecticides adjuvant, excipient is wanted to be configured on pesticide any one dosage form allowed.
Bactericidal composition the most according to claim 7, it is characterised in that described dosage form is cream, suspending agent, water Emulsion, wettable powder or water dispersion granule.
9. the application on preparation preventing and treating fungal diseases of plants medicine of the bactericidal composition described in claim 1.
Application the most according to claim 9, it is characterised in that described fungal diseases of plants is leaf spot, leaf rust At least one in disease, downy mildew, rice blast, damping-off.
CN201610356431.0A 2016-05-25 2016-05-25 Sterilization composition containing Bixafen and Tiadinil and application thereof Pending CN105961409A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109418270A (en) * 2017-09-01 2019-03-05 浙江省化工研究院有限公司 A kind of bactericidal composition of fluorine-containing phenylate amide

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109418270A (en) * 2017-09-01 2019-03-05 浙江省化工研究院有限公司 A kind of bactericidal composition of fluorine-containing phenylate amide

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Application publication date: 20160928

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