CN105994284A - Antibacterial composition containing bixafen and fenamidone as well as application of antibacterial composition - Google Patents

Antibacterial composition containing bixafen and fenamidone as well as application of antibacterial composition Download PDF

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Publication number
CN105994284A
CN105994284A CN201610355528.XA CN201610355528A CN105994284A CN 105994284 A CN105994284 A CN 105994284A CN 201610355528 A CN201610355528 A CN 201610355528A CN 105994284 A CN105994284 A CN 105994284A
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Prior art keywords
fenamidone
bacterium amine
pyrrole bacterium
biphenyl pyrrole
bactericidal composition
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CN201610355528.XA
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Inventor
郭崇友
赵东亚
孙会杰
程清云
邢刚
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Nanjing Huazhou Pharmaceutical Co Ltd
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Nanjing Huazhou Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/501,3-Diazoles; Hydrogenated 1,3-diazoles

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses antibacterial composition containing bixafen and fenamidone as well as application of the antibacterial composition. The antibacterial composition comprises bixafen and fenamidone as main effective components, wherein the mass ratio of bixafen to fenamidone is (1-70):(1-50). The antibacterial composition can be applied to control on cereal, fruit tree and vegetable diseases, is relatively good in synergistic interaction, overcomes and retards drug resistance of bacteria and is high in sterilization speed, long in lasting period and low in application cost, and the control of the bacterial composition is remarkably superior to that of a single agent. The antibacterial composition can be used for controlling fungal diseases on crops, particularly for controlling fungal diseases such as powdery mildew, rust diseases, damping off, downy mildew, late blight, phytophthora root rot, damping-off, black spot and spotted necrosis, and the effect is remarkably superior to that of the single agent.

Description

A kind of containing biphenyl pyrrole bacterium amine and the bactericidal composition of Fenamidone and application
Technical field:
The present invention relates to a kind of bactericidal composition and application thereof, especially one is main with biphenyl pyrrole bacterium amine and Fenamidone The bactericidal composition of active component and application thereof.
Background technology
Biphenyl pyrrole bacterium amine (Bixafen), chemical formula: C18H12Cl2F3N3O, chemical name: N-(3 ', 4 '-two chloro-5- Fluorine hexichol-2-base)-3-(difluoromethyl)-1-methylpyrazole-4-Methanamide.Structural formula:
Biphenyl pyrrole bacterium amine is pyrazoles antibacterial, is that the interior absorption that a kind of novel wide spectrum, protection and therapeutic activity have concurrently is killed Microbial inoculum.
Fenamidone (Fenamidone), molecular formula: C17H17N3OS, chemical name: (S)-1-phenylamino-4-methyl -2-methyl mercapto-4-phenyl-2-imidazoline-5-ketone.Structural formula:
Fenamidone applicable crops Semen Tritici aestivi, Cotton Gossypii, Fructus Vitis viniferae, Nicotiana tabacum L., lawn, Helianthi, Flos Rosae Rugosae, Rhizoma Solani tuber osi, Fructus Lycopersici esculenti Sick etc. the downy mildew of various vegetables, late blight, phytophthora root rot, damping off, melasma, mottled rot etc..
The difficulty of prevention and cure of phytopathogen is increasing at present, on the one hand, along with the change of pattern of farming, melon fruits and vegetables etc. Industrial crops cultivated area progressively expands, and disease occurrence degree, generation quantity all increase, and in preventing and treating, difficulty strengthens; On the other hand, the resistance of pathogen rises under lasting medicament selection pressure year by year, and the prevention effect of single dose is had a greatly reduced quality, Control of plant disease is faced with significant challenge.
Summary of the invention:
It is an object of the invention to provide a kind of applied widely, low cost for above-mentioned technical problem, effective containing biphenyl Pyrrole bacterium amine and the plant bactericidal composition of Fenamidone.
It is a still further object of the present invention to provide this bactericidal composition and cause the application on fungal disease at preventing and treating plant epiphyte, Especially in the purposes prevented and treated on the fungal diseases such as powdery mildew, rust, downy mildew, damping-off, eyeprint disease.
It is an object of the invention to be achieved through the following technical solutions:
A kind of containing biphenyl pyrrole bacterium amine and the bactericidal composition of Fenamidone, this bactericidal composition is with biphenyl pyrrole bacterium amine and imidazoles bacterium Ketone is principle active component, and wherein biphenyl pyrrole bacterium amine is 1~70:1~50 with the mass ratio of Fenamidone, wherein sterilization group In compound, active ingredient is present in compositions with enhancing effective amount.
Described bactericidal composition, wherein biphenyl pyrrole bacterium amine is preferably 1~50:1~50 with the mass ratio of Fenamidone, enters One step is preferably 1~50:1~4, the most preferably 20~50:1~4.Biphenyl pyrrole bacterium amine is preferred with Fenamidone Quality proportioning can also be: 70:1,50:1,30:1,20:1,10:1,5:1,2.5:1,1:1,1:2, 1:4,1:6,1:10,1:20,1:30,1:50.
In the compositions of the present invention, the weight/mass percentage composition accounting for compositions both biphenyl pyrrole bacterium amine and Fenamidone is 2~80%.Preferably 5~70%.
Described bactericidal composition, wherein with biphenyl pyrrole bacterium amine and Fenamidone for principle active component and known auxiliary agent and Excipient is re-dubbed on pesticide any one dosage form allowed.Auxiliary agent known to these, excipient have dispersant, diffusant, Defoamer, wetting agent, disintegrating agent etc., can use calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, benzylphenol Polyoxyethylene ether, phenethyl phenol polyethenoxy ether, fatty alcohol-polyoxyethylene ether and similar products, aliphatic amine polyoxyethylene Ether, fatty acid ethylene oxide addition product, polyoxyethylene polyoxy propylene block compound, castor oil polyoxyethylene ether, nonyl Phenol polyethenoxy ether, TWEEN Series, fatty alcohol-polyoxyethylene ether, Polyethylene Glycol series, Sulfonates, carboxylate, sulfur Hydrochlorate, phosphate, phosphite, lignosulfonates, xanthan gum, phenol formaldehyde condensate, ammonium salt, quaternary etc. In one or more combinations, excipient includes that Ketohexamethylene, dimethylbenzene, various solvent naphtha, water, antifreezing agent are (such as the third two Alcohol), deionized water etc..Above auxiliary agent, excipient and other adjuvant can be alone or and use.
Described bactericidal composition, its dosage form is cream, wettable powder, suspending agent, aqueous emulsion or water dispersion granule.
The application on preparation preventing and treating fungal diseases of plants medicine of the above-mentioned bactericidal composition.Especially preventing and treating Cereal, Application in terms of fruit tree, vegetable crop disease has significant effect.
Above-mentioned application, described fungal diseases of plants is powdery mildew, rust, damping-off, downy mildew, late blight, epidemic disease At least one in mildew, damping off, melasma, mottled rot disease.
The feature of bactericidal composition of the present invention:
1, the biphenyl pyrrole bacterium amine used by the present invention and Fenamidone, the mechanism of action is different, and mutual mixture will not produce low touching, Can Synergistic, reduce dosage, reduce cost.
2, the present composition scope of application increases, it is adaptable to preventing and treating Cereal, fruit tree, the refractory fungal disease of vegetable, Particularly prevent and treat powdery mildew, rust, damping-off, downy mildew, late blight, phytophthora root rot, damping off, melasma, mottled rot Disease etc. all has significant effect.Bactericidal composition of the present invention is to ascomycetes, basidiomycetes, Fungi Imperfecti and Oomycete fungal disease There is good prevention effect;And (biphenyl pyrrole bacterium amine and Fenamidone are appointed to unitary agent to suppress insect or fungus or antibacterial One) drug-fast generation.Bactericidal composition of the present invention can produce higher synergistic function, and this mixture The consumption of the independent reactive compound of amount ratio is substantially reduced, and i.e. the activity of mixture is more than the activity of independent component.
Compared with prior art beneficial effects of the present invention: (1), compared with single dose, said composition antagonism fungal disease is such as The mycosises such as powdery mildew, rust, damping-off, downy mildew, late blight, phytophthora root rot, damping off, melasma, mottled rot are sick Evil has obvious synergistic function, overcomes and delayed Drug resistance, and expanding prevention is composed, hence it is evident that improve prevention effect;(2) Reduce preventing and treating recruitment, drug cost;(3) alternative routine and the pesticide being easily generated resistance;(4) compared with single dose, raw Produce and use cost reduces;(5) the suppression drug-fast generation of fungus, its effect uses apparently higher than its single dose.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, and in embodiment, the preparation method of dosage form is conventional method, " % " of the present invention is mass percent.
Indoor biometrics is tested:
In indoor employing mycelial growth rate method, measure the different agents EC to bacterial strain50Value, uses co-toxicity coefficient calculating side Method, calculates the co-toxicity coefficient (CTC) of mixture, determines the building performance of mixture, and circular is as follows:
In mixture, a certain single dose (is generally selected EC as standard agent50Junior), calculate:
Single dose toxicity index=standard agent EC50/ certain single dose EC50×100
Toxicity index × A the single dose of theoretical toxicity index=A single dose in mixture the toxicity index of proportion+B single dose × B single dose proportion in mixture
The EC of actual measurement toxicity index=standard single dose50The EC of value/mixture50Value × 100
Co-toxicity coefficient=actual measurement toxicity index/theory toxicity index × 100
When co-toxicity coefficient classification: CTC is more than 120, mixture has synergetic, is antagonism when CTC is less than 80, CTC It it is summation action between 80-120.
According to effective ingredient biphenyl pyrrole bacterium amine (A): Fenamidone (B) quality proportioning is: 70:1,50:1,30: 1,20:1,10:1,5:1,2.5:1,1:1,1:2,1:4,1:6,1:10,1:20,1:30,1: 50 test, and measure its co-toxicity coefficient to tomato late blight (Phytophthora infestans.).
Table 1: biphenyl pyrrole bacterium amine+Fenamidone different ratio indoor biometrics result to tomato late blight
Medicament Virulence regression equation EC50(mg/L) Co-toxicity coefficient
10% biphenyl pyrrole bacterium amine WP Y=4.200+1.221X 4.522 -
40% Fenamidone SC Y=2.214+3.625X 5.869 -
A:B=70:1 Y=3.621+2.052X 4.701 125.26
A:B=50:1 Y=3.428+2.698X 3.825 154.12
A:B=30:1 Y=3.002+3.635X 3.500 168.96
A:B=20:1 Y=4.403+1.210X 3.115 190.52
A:B=10:1 Y=3.707+2.002X 4.424 135.48
A:B=5:1 Y=2.246+4.360X 4.281 142.56
A:B=2.5:1 Y=2.996+2.982X 4.701 133.60
A:B=1:1 Y=4.004+1.598X 4.200 157.84
A:B=1:2 Y=4.231+1.254X 4.101 168.95
A:B=1:4 Y=2.983+3.630X 3.594 200.01
A:B=1:6 Y=3.542+1.897X 5.872 124.42
A:B=1:10 Y=2.683+3.554X 4.487 165.29
A:B=1:20 Y=1.521+5.087X 4.829 155.52
A:B=1:30 Y=2.062+4.521X 4.465 168.96
A:B=1:50 Y=3.274+2.665X 4.442 170.48
Field control effectiveness test:
The pesticidal preparations preventing and treating tomato late blight test prepared with above-described embodiment.
1, test processes: this test medicine consumption sets three concentration for the treatment of respectively according to the difference of each composition, compares medicine Agent is pesticide single dose 10% biphenyl pyrrole bacterium amine WP and 40% Fenamidone SC and blank clean water experiment respectively.
2, each plot area of test method is 66.7m2, it is repeated 3 times;Investigation drug effect after investigating before dispenser and preventing and treating Method is: in test treatment region, (every takes 5m to randomization 5 point2), enter according to country's field test relevant criterion Row severity Scaling, calculates preventive effect.Result of the test is shown in Table 2:
Table 2 field test effect
Being shown by indoor biometrics and field efficacy result, biphenyl pyrrole bacterium amine and Fenamidone compositions have the most collaborative Potentiation, the prevention effect of compositions is excellent, and prevention effect is all better than single dose kind, has application in agricultural is applied It is worth.
Two kinds of reactive compounds can be processed into any one dosage form of permission, illustrates that two kinds have with specific embodiment below The preparation that effect composition is processed into, but the preparation that these two kinds of active component can be processed is not limited only to set forth below.
Embodiment 1:15% biphenyl pyrrole bacterium amine Fenamidone wettable powder (1:2)
By biphenyl pyrrole bacterium amine 5g, Fenamidone 10g, detergent LS (to methoxyl group fatty acid amido benzene sulfonic acid sodium salt) 2g, Dispersing agent NNO (sodium methylene bis-naphthalene sulfonate) 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out air-flow powder Broken, preparing effective ingredient mass percent is 15% biphenyl pyrrole bacterium amine Fenamidone wettable powder.
Embodiment 2:15% biphenyl pyrrole bacterium amine Fenamidone wettable powder (1:4)
By biphenyl pyrrole bacterium amine 3g, Fenamidone 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient mass percent is 15% biphenyl pyrrole bacterium amine miaow Cycloheximide triazole wettable powder.
Embodiment 3:14% biphenyl pyrrole bacterium amine Fenamidone wettable powder (1:6)
By biphenyl pyrrole bacterium amine 2g, Fenamidone 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient mass percent is 14% biphenyl pyrrole bacterium amine miaow Cycloheximide triazole wettable powder.
Embodiment 4:20% biphenyl pyrrole bacterium amine Fenamidone suspending agent (1:1)
Weigh 10g biphenyl pyrrole bacterium amine, 10g Fenamidone, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate thereof 4g, xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand Making effective Ingredient percent under the effect of grinding machine is 20% biphenyl pyrrole bacterium amine Fenamidone suspending agent.
Embodiment 5:55% biphenyl pyrrole bacterium amine Fenamidone aqueous emulsion (1:10)
Weigh 5g biphenyl pyrrole bacterium amine, 50g Fenamidone, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, Alkylphenol polyoxyethylene 1g, 150# solvent naphtha 13g, add water to 100g.Above raw material is prepared aqueous emulsion routinely Method puts into the mixing of mixing kettle high speed, and making effective Ingredient percent is 55% biphenyl pyrrole bacterium amine Fenamidone water Emulsion.
Embodiment 6:42% biphenyl pyrrole bacterium amine Fenamidone cream (1:20)
Weigh 2g biphenyl pyrrole bacterium amine, 40g Fenamidone, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is formed with Effect Ingredient percent is 42% biphenyl pyrrole bacterium amine Fenamidone cream.
Embodiment 7:70% biphenyl pyrrole bacterium amine Fenamidone cream (2.5:1)
Weigh 50g biphenyl pyrrole bacterium amine, 20g Fenamidone, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g, castor oil polyoxyethylene ether 2g, 150# solvent naphtha to 100g.The method that above raw material is prepared cream routinely is thrown Entering in mixing kettle and mix, making effective Ingredient percent is 70% biphenyl pyrrole bacterium amine Fenamidone cream.
Embodiment 8:18% biphenyl pyrrole bacterium amine Fenamidone water dispersion granule (5:1)
Weigh 15g biphenyl pyrrole bacterium amine, 3g Fenamidone, wooden sodium sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, Borax 2g, kieselguhr complements to 100g, is made by water dispersible granular agent method by above raw material Effective ingredient mass percent is 17% biphenyl pyrrole bacterium amine Fenamidone water dispersion granule.
Embodiment 9:11% biphenyl pyrrole bacterium amine Fenamidone cream (10:1)
Weigh 10g biphenyl pyrrole bacterium amine, 1g Fenamidone, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is formed with Effect Ingredient percent is 11% biphenyl pyrrole bacterium amine Fenamidone cream.
Embodiment 10:31.5% biphenyl pyrrole bacterium amine Fenamidone microemulsion (20:1)
Weigh 30g biphenyl pyrrole bacterium amine, 1.5g Fenamidone, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether Phosphate ester 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.To be the most former Material is prepared the method for microemulsion routinely and is put into mixing in mixing kettle, and making effective Ingredient percent is 31.5% biphenyl Pyrrole bacterium amine Fenamidone microemulsion.
Embodiment 11:31% biphenyl pyrrole bacterium amine Fenamidone cream (30:1)
Weigh 30g biphenyl pyrrole bacterium amine, 1g Fenamidone, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, is formed with Effect Ingredient percent is 31% biphenyl pyrrole bacterium amine Fenamidone cream.
Embodiment 12:51% biphenyl pyrrole bacterium amine Fenamidone suspending agent (50:1)
Weigh 50g biphenyl pyrrole bacterium amine, 1g Fenamidone, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate thereof 4g, xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand Making effective Ingredient percent under the effect of grinding machine is 51% biphenyl pyrrole bacterium amine Fenamidone suspending agent.
Embodiment 13:32% biphenyl pyrrole bacterium amine Fenamidone microemulsion (1:15)
Weigh 2g biphenyl pyrrole bacterium amine, 30g Fenamidone, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether Phosphate ester 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.To be the most former Material is prepared the method for microemulsion routinely and is put into mixing in mixing kettle, and making effective Ingredient percent is 32% biphenyl pyrrole Bacterium amine Fenamidone microemulsion.
Embodiment 14:6% biphenyl pyrrole bacterium amine Fenamidone aqueous emulsion (1:5)
Weigh 1g biphenyl pyrrole bacterium amine, 5g Fenamidone, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, Alkylphenol polyoxyethylene 1g, 150# solvent naphtha 13g, add water to 100g.Above raw material is prepared aqueous emulsion routinely Method puts into the mixing of mixing kettle high speed, and making effective Ingredient percent is 6% biphenyl pyrrole bacterium amine Fenamidone water and milk Agent.
Embodiment 15:62% biphenyl pyrrole bacterium amine Fenamidone microemulsion (1:30)
Weigh 2g biphenyl pyrrole bacterium amine, 60g Fenamidone, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether Phosphate ester 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.To be the most former Material is prepared the method for microemulsion routinely and is put into mixing in mixing kettle, and making effective Ingredient percent is 62% biphenyl pyrrole Bacterium amine Fenamidone microemulsion.
Embodiment 16:51% biphenyl pyrrole bacterium amine Fenamidone suspending agent (1:50)
Weigh 1g biphenyl pyrrole bacterium amine, 50g Fenamidone, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate thereof 4g, xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand Making effective Ingredient percent under the effect of grinding machine is 51% biphenyl pyrrole bacterium amine Fenamidone suspending agent.
Embodiment 17:7% biphenyl pyrrole bacterium amine Fenamidone water dispersion granule (1:2.5)
Weigh 2g biphenyl pyrrole bacterium amine, 5g Fenamidone, wooden sodium sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, Borax 2g, white carbon 3g, kieselguhr complement to 100g, above raw material are pressed water dispersible granular It is 7% biphenyl pyrrole bacterium amine Fenamidone water dispersion granule that agent method makes effective Ingredient percent.

Claims (10)

1. one kind contains biphenyl pyrrole bacterium amine and the bactericidal composition of Fenamidone, it is characterised in that this bactericidal composition is with biphenyl Pyrrole bacterium amine and Fenamidone are principle active component, and wherein biphenyl pyrrole bacterium amine is 1~70:1~50 with the mass ratio of Fenamidone.
Bactericidal composition the most according to claim 1, it is characterised in that described biphenyl pyrrole bacterium amine and Fenamidone Mass ratio is 1~50:1~50.
Bactericidal composition the most according to claim 2, it is characterised in that described biphenyl pyrrole bacterium amine and Fenamidone Mass ratio is 1~50:1~4.
Bactericidal composition the most according to claim 3, it is characterised in that described biphenyl pyrrole bacterium amine and Fenamidone Mass ratio is 20~50:1~4.
Bactericidal composition the most according to claim 1, it is characterised in that described biphenyl pyrrole bacterium amine and Fenamidone The two weight/mass percentage composition accounting for compositions is 2-80%.
Bactericidal composition the most according to claim 5, it is characterised in that described biphenyl pyrrole bacterium amine and Fenamidone The two weight/mass percentage composition accounting for compositions is 10-40%.
Bactericidal composition the most according to claim 1, it is characterised in that based on biphenyl pyrrole bacterium amine and Fenamidone Effective ingredient and insecticides adjuvant, excipient is wanted to be configured on pesticide any one dosage form allowed.
Bactericidal composition the most according to claim 7, it is characterised in that described dosage form is cream, suspending agent, water Emulsion, wettable powder or water dispersion granule.
9. the application on preparation preventing and treating fungal diseases of plants medicine of the bactericidal composition described in claim 1.
Application the most according to claim 9, it is characterised in that described fungal diseases of plants be powdery mildew, rust, At least one in damping-off, downy mildew, late blight, phytophthora root rot, damping off, melasma, mottled rot disease.
CN201610355528.XA 2016-05-25 2016-05-25 Antibacterial composition containing bixafen and fenamidone as well as application of antibacterial composition Pending CN105994284A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011043876A1 (en) * 2009-10-07 2011-04-14 Dow Agrosciences Llc Synergistic fungicidal composition containing 5-fluorocytosine for fungal control in cereals
US20120015910A1 (en) * 2003-10-10 2012-01-19 Bayer Cropscience Ag Synergistic fungicidal active substance combinations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120015910A1 (en) * 2003-10-10 2012-01-19 Bayer Cropscience Ag Synergistic fungicidal active substance combinations
WO2011043876A1 (en) * 2009-10-07 2011-04-14 Dow Agrosciences Llc Synergistic fungicidal composition containing 5-fluorocytosine for fungal control in cereals

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