CN105941417A - Sterilization composition containing Bixafen and epoxiconazole and application thereof - Google Patents

Sterilization composition containing Bixafen and epoxiconazole and application thereof Download PDF

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Publication number
CN105941417A
CN105941417A CN201610355222.4A CN201610355222A CN105941417A CN 105941417 A CN105941417 A CN 105941417A CN 201610355222 A CN201610355222 A CN 201610355222A CN 105941417 A CN105941417 A CN 105941417A
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Prior art keywords
epoxiconazole
bacterium amine
pyrrole bacterium
biphenyl pyrrole
bactericidal composition
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CN201610355222.4A
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Inventor
白杰
郭崇友
张宝俊
万维肖
石振龙
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Nanjing Huazhou Pharmaceutical Co Ltd
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Nanjing Huazhou Pharmaceutical Co Ltd
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Priority to CN201610355222.4A priority Critical patent/CN105941417A/en
Publication of CN105941417A publication Critical patent/CN105941417A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647Triazoles; Hydrogenated triazoles
    • A01N43/6531,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a sterilization composition containing Bixafen and epoxiconazole and application thereof. The sterilization composition takes the Bixafen and the epoxiconazole as main effective ingredients, wherein the mass ratio of the Bixafen to the epoxiconazole is (1-70):(1-50). The sterilization composition can be used for preventing and curing cereal, fruit tree and vegetable diseases, has a higher synergistic interaction action, overcomes and delays the drug resistance of bacteria, has the advantages of high sterilization speed and long lasting period and lowers application cost, and the prevention and cure effect of the sterilization composition is obviously superior to the prevention and cure effect brought when the Bixafen or the epoxiconazole is singly used. The sterilization composition can be used for preventing and curing fungi on crops, and can be especially used for preventing and curing fungal diseases including powdery mildew, rust disease, downy mildew, damping off, Pseudocercosporella herpotrichoides and the like, and the effect of the sterilization composition is obviously superior to the effect brought when the Bixafen or the epoxiconazole is singly used.

Description

A kind of containing biphenyl pyrrole bacterium amine and the bactericidal composition of epoxiconazole and application
Technical field:
The present invention relates to a kind of bactericidal composition and application thereof, especially one live with biphenyl pyrrole bacterium amine and epoxiconazole for main The bactericidal composition of property composition and application thereof.
Background technology
Biphenyl pyrrole bacterium amine (Bixafen), chemical formula: C18H12Cl2F3N3O, chemical name: N-(3 ', 4 '-two chloro-5- Fluorine hexichol-2-base)-3-(difluoromethyl)-1-methylpyrazole-4-Methanamide.Structural formula:
Biphenyl pyrrole bacterium amine is pyrazoles antibacterial, is that the interior absorption that a kind of novel wide spectrum, protection and therapeutic activity have concurrently is killed Microbial inoculum.
Epoxiconazole (epoxiconazole), molecular formula: C17H13ClFN3O, chemical name: (2RS, 3SR)-1-[3-(2- Chlorphenyl)-2,3-oxygen bridge-2-(4-fluorophenyl) propyl group]-1H-1,2,4-triazole.Structural formula:
Epoxiconazole is triazole bactericidal agent, to kinds more than ten such as a series of cereal crops such as damping-off, powdery mildew, eyeprint diseases Disease has good preventive and therapeutic effect, and can prevent and treat sugar beet, Semen arachidis hypogaeae, Brassica campestris L, lawn, coffee, Oryza sativa L. and fruit tree Etc. disease.Not only have and well protect, treat and root out activity, and there is interior suction and preferably residual activity..
The difficulty of prevention and cure of phytopathogen is increasing at present, on the one hand, along with the change of pattern of farming, melon fruits and vegetables etc. Industrial crops cultivated area progressively expands, and disease occurrence degree, generation quantity all increase, and in preventing and treating, difficulty strengthens; On the other hand, the resistance of pathogen rises under lasting medicament selection pressure year by year, and the prevention effect of single dose is had a greatly reduced quality, Control of plant disease is faced with significant challenge.
Summary of the invention:
It is an object of the invention to provide a kind of applied widely, low cost for above-mentioned technical problem, effective containing biphenyl Pyrrole bacterium amine and the plant bactericidal composition of epoxiconazole.
It is a still further object of the present invention to provide this bactericidal composition and cause the application on fungal disease at preventing and treating plant epiphyte, Especially in the purposes prevented and treated on the fungal diseases such as powdery mildew, rust, downy mildew, damping-off, eyeprint disease.
It is an object of the invention to be achieved through the following technical solutions:
A kind of containing biphenyl pyrrole bacterium amine and the bactericidal composition of epoxiconazole, this bactericidal composition with biphenyl pyrrole bacterium amine with epoxiconazole is Principle active component, wherein biphenyl pyrrole bacterium amine is 1~70:1~50 with the mass ratio of epoxiconazole, wherein in bactericidal composition Active ingredient is present in compositions with enhancing effective amount.
Described bactericidal composition, wherein biphenyl pyrrole bacterium amine is preferably 1~50:1~50 with the mass ratio of epoxiconazole, enters one Step is preferably 1~30:2~50, the most preferably 1~30:2~10.Biphenyl pyrrole bacterium amine and the preferred mass of epoxiconazole Proportioning can also be: 70:1,50:1,30:1,20:1,10:1,5:1,2.5:1,1:1,1:2,1: 4,1:6,1:10,1:20,1:30,1:50.
In the compositions of the present invention, the weight/mass percentage composition accounting for compositions both biphenyl pyrrole bacterium amine and epoxiconazole is 2~80%. Preferably 5~70%.
Described bactericidal composition, wherein with biphenyl pyrrole bacterium amine and epoxiconazole for principle active component and known auxiliary agent and tax Shape agent is re-dubbed on pesticide any one dosage form allowed.Auxiliary agent known to these, excipient have dispersant, diffusant, Defoamer, wetting agent, disintegrating agent etc., can use calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, benzylphenol Polyoxyethylene ether, phenethyl phenol polyethenoxy ether, fatty alcohol-polyoxyethylene ether and similar products, aliphatic amine polyoxyethylene Ether, fatty acid ethylene oxide addition product, polyoxyethylene polyoxy propylene block compound, castor oil polyoxyethylene ether, nonyl Phenol polyethenoxy ether, TWEEN Series, fatty alcohol-polyoxyethylene ether, Polyethylene Glycol series, Sulfonates, carboxylate, sulfur Hydrochlorate, phosphate, phosphite, lignosulfonates, xanthan gum, phenol formaldehyde condensate, ammonium salt, quaternary etc. In one or more combinations, excipient includes that Ketohexamethylene, dimethylbenzene, various solvent naphtha, water, antifreezing agent are (such as the third two Alcohol), deionized water etc..Above auxiliary agent, excipient and other adjuvant can be alone or and use.
Described bactericidal composition, its dosage form is cream, wettable powder, suspending agent, aqueous emulsion or water dispersion granule.
The application on preparation preventing and treating fungal diseases of plants medicine of the above-mentioned bactericidal composition.Especially preventing and treating Cereal, Application effect in terms of fruit tree, vegetable crop disease is significantly better than single dose and uses.
Above-mentioned application, described fungal diseases of plants is in powdery mildew, rust, downy mildew, damping-off, eyeprint disease At least one.
The feature of bactericidal composition of the present invention:
1, the biphenyl pyrrole bacterium amine used by the present invention and epoxiconazole, the mechanism of action is different, and mutual mixture will not produce low touching, Can Synergistic, reduce dosage, reduce cost.
2, the present composition scope of application increases, it is adaptable to preventing and treating Cereal, fruit tree, the refractory fungal disease of vegetable, Particularly prevent and treat powdery mildew, rust, downy mildew, damping-off, eyeprint disease etc. and all have significant effect.Sterilization group of the present invention Compound has good prevention effect to ascomycetes, basidiomycetes, Fungi Imperfecti and Oomycete fungal disease;And suppress insect or Fungus or the antibacterial drug-fast generation to unitary agent (biphenyl pyrrole bacterium amine and epoxiconazole are arbitrary).Bactericidal composite of the present invention Thing can produce higher synergistic function, and the consumption of the independent reactive compound of amount ratio of this mixture drops significantly Low, i.e. the activity of mixture is more than the activity of independent component.
Compared with prior art beneficial effects of the present invention: (1), compared with single dose, said composition antagonism fungal disease is such as The fungal diseases such as powdery mildew, rust, downy mildew, damping-off, eyeprint are sick have obvious synergistic function, overcome and delay Drug resistance, expanding prevention is composed, hence it is evident that improve prevention effect;(2) preventing and treating recruitment, drug cost are reduced;(3) may be used Substitute pesticide that is conventional and that be easily generated resistance;(4) compared with single dose, produce and use cost reduces;(5) suppression fungus Drug-fast generation, its effect uses apparently higher than its single dose.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, and in embodiment, the preparation method of dosage form is conventional method, " % " of the present invention is mass percent.
Indoor biometrics is tested:
In indoor employing mycelial growth rate method, measure the different agents EC to bacterial strain50Value, uses co-toxicity coefficient calculating side Method, calculates the co-toxicity coefficient (CTC) of mixture, determines the building performance of mixture, and circular is as follows:
In mixture, a certain single dose (is generally selected EC as standard agent50Junior), calculate:
Single dose toxicity index=standard agent EC50/ certain single dose EC50×100
Toxicity index × A the single dose of theoretical toxicity index=A single dose in mixture the toxicity index of proportion+B single dose × B single dose proportion in mixture
The EC of actual measurement toxicity index=standard single dose50The EC of value/mixture50Value × 100
Co-toxicity coefficient=actual measurement toxicity index/theory toxicity index × 100
When co-toxicity coefficient classification: CTC is more than 120, mixture has synergetic, is antagonism when CTC is less than 80, CTC It it is summation action between 80-120.
According to effective ingredient biphenyl pyrrole bacterium amine (A): epoxiconazole (B) quality proportioning is: 80:1,70:1,50:1, 30:1,20:1,10:1,5:1,2.5:1,1:1,1:2,1:4,1:6,1:10,1:20,1: 30,1:50,1:60,1:70 test, and measure its common poison to uncinula necator (Uncinula necator.) Coefficient.
Table 1: biphenyl pyrrole bacterium amine+epoxiconazole different ratio indoor biometrics result to uncinula necator
Medicament Virulence regression equation EC50(mg/L) Co-toxicity coefficient
10% biphenyl pyrrole bacterium amine WP Y=4.978+2.057X 1.025 -
25% epoxiconazole EC Y=3.007+3.526X 3.674 -
A:B=80:1 Y=4.852+0.258X 3.758 98.63
A:B=70:1 Y=3.912+2.302X 2.968 125.04
A:B=50:1 Y=4.430+1.580X 2.296 162.32
A:B=30:1 Y=4.613+1.254X 2.036 184.71
A:B=20:1 Y=3.985+2.512X 2.536 150.02
A:B=10:1 Y=4.152+2.330X 2.311 170.12
A:B=5:1 Y=3.049+4.012X 3.064 136.29
A:B=2.5:1 Y=2.340+5.302X 3.175 145.75
A:B=1:1 Y=2.513+4.152X 3.972 144.63
A:B=1:2 Y=3.077+3.369X 3.722 190.08
A:B=1:4 Y=2.933+2.754X 5.631 154.17
A:B=1:6 Y=3.843+1.536X 5.662 169.86
A:B=1:10 Y=4.788+0.254X 6.845 155.78
A:B=1:20 Y=1.903+3.232X 9.084 129.08
A:B=1:30 Y=1.155+4.112X 8.612 141.14
A:B=1:50 Y=0.833+5.003X 6.807 184.12
A:B=1:60 Y=2.673+2.228X 11.078 114.04
A:B=1:70 Y=1.037+3.625X 12.393 102.53
Field control effectiveness test:
The pesticidal preparations preventing and treating uncinula necator test prepared with above-described embodiment.
1, test processes: this test medicine consumption sets three concentration for the treatment of respectively according to the difference of each composition, compares medicine Agent is pesticide single dose 10% biphenyl pyrrole bacterium amine WP and 25% epoxiconazole EC and blank clean water experiment respectively.
2, each plot area of test method is 66.7m2, it is repeated 3 times;Investigation drug effect after investigating before dispenser and preventing and treating Method is: randomization 5 point in test treatment region, carries out severity Scaling according to country's field test relevant criterion, meter Calculate preventive effect.Result of the test is shown in Table 2:
Table 2 field test effect
Being shown by indoor biometrics and field efficacy result, biphenyl pyrrole bacterium amine and epoxiconazole composition have the most collaborative increasing Effect effect, the prevention effect of compositions is excellent, and prevention effect is all better than single dose kind, has application valency in agricultural is applied Value.
Two kinds of reactive compounds can be processed into any one dosage form of permission, illustrates that two kinds have with specific embodiment below The preparation that effect composition is processed into, but the preparation that these two kinds of active component can be processed is not limited only to set forth below.
Embodiment 1:15% biphenyl pyrrole bacterium amine epoxiconazole wettable powder (1:2)
By biphenyl pyrrole bacterium amine 5g, epoxiconazole 10g, detergent LS (to methoxyl group fatty acid amido benzene sulfonic acid sodium salt) 2g, Dispersing agent NNO (sodium methylene bis-naphthalene sulfonate) 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out air-flow powder Broken, preparing effective ingredient mass percent is 15% biphenyl pyrrole bacterium amine epoxiconazole wettable powder.
Embodiment 2:15% biphenyl pyrrole bacterium amine epoxiconazole wettable powder (1:4)
By biphenyl pyrrole bacterium amine 3g, epoxiconazole 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient mass percent is 15% biphenyl pyrrole bacterium amine fluorine Ring azoles wettable powder.
Embodiment 3:14% biphenyl pyrrole bacterium amine epoxiconazole wettable powder (1:6)
By biphenyl pyrrole bacterium amine 2g, epoxiconazole 12g, sodium lauryl sulphate 3g, dispersing agent NNO 4g, white carbon 5g, Kaolin adds to 100g mixture and carries out comminution by gas stream, and preparing effective ingredient mass percent is 14% biphenyl pyrrole bacterium amine fluorine Ring azoles wettable powder.
Embodiment 4:20% biphenyl pyrrole bacterium amine epoxiconazole suspension concentrate (1:1)
Weigh 10g biphenyl pyrrole bacterium amine, 10g epoxiconazole, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate 4g thereof, Xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand mill Effect under to make effective Ingredient percent be 20% biphenyl pyrrole bacterium amine epoxiconazole suspension concentrate.
Embodiment 5:55% biphenyl pyrrole bacterium amine epoxiconazole aqueous emulsion (1:10)
Weigh 5g biphenyl pyrrole bacterium amine, 50g epoxiconazole, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, Alkylphenol polyoxyethylene 1g, 150# solvent naphtha 13g, add water to 100g.Above raw material is prepared aqueous emulsion routinely Method puts into the mixing of mixing kettle high speed, and making effective Ingredient percent is 55% biphenyl pyrrole bacterium amine epoxiconazole water and milk Agent.
Embodiment 6:42% biphenyl pyrrole bacterium amine epoxiconazole cream (1:20)
Weigh 2g biphenyl pyrrole bacterium amine, 40g epoxiconazole, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, makes effectively one-tenth Point mass percent is 42% biphenyl pyrrole bacterium amine epoxiconazole cream.
Embodiment 7:70% biphenyl pyrrole bacterium amine epoxiconazole cream (2.5:1)
Weigh 50g biphenyl pyrrole bacterium amine, 20g epoxiconazole, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g, Castor oil polyoxyethylene ether 2g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixed Closing in still and mix, making effective Ingredient percent is 70% biphenyl pyrrole bacterium amine epoxiconazole cream.
Embodiment 8:18% biphenyl pyrrole bacterium amine epoxiconazole water dispersion granule (5:1)
Weigh 15g biphenyl pyrrole bacterium amine, 3g epoxiconazole, wooden sodium sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g, Polyvinyl alcohol 5g, Borax 2g, kieselguhr complements to 100g, and by water dispersible granular agent method, above raw material is formed with effect Ingredient percent is 17% biphenyl pyrrole bacterium amine epoxiconazole water dispersion granule.
Embodiment 9:11% biphenyl pyrrole bacterium amine epoxiconazole cream (10:1)
Weigh 10g biphenyl pyrrole bacterium amine, 1g epoxiconazole, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, makes effectively one-tenth Point mass percent is 11% biphenyl pyrrole bacterium amine epoxiconazole cream.
Embodiment 10:31.5% biphenyl pyrrole bacterium amine epoxiconazole microemulsion (20:1)
Weigh 30g biphenyl pyrrole bacterium amine, 1.5g epoxiconazole, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphorus Acid esters 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.By above raw material The method preparing microemulsion routinely puts into mixing in mixing kettle, and making effective Ingredient percent is 31.5% biphenyl pyrrole Bacterium amine epoxiconazole microemulsion.
Embodiment 11:31% biphenyl pyrrole bacterium amine epoxiconazole cream (30:1)
Weigh 30g biphenyl pyrrole bacterium amine, 1g epoxiconazole, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, 150# solvent naphtha is to 100g.The method that above raw material is prepared cream routinely puts into mixing in mixing kettle, makes effectively one-tenth Point mass percent is 31% biphenyl pyrrole bacterium amine epoxiconazole cream.
Embodiment 12:51% biphenyl pyrrole bacterium amine epoxiconazole suspension concentrate (50:1)
Weigh 50g biphenyl pyrrole bacterium amine, 1g epoxiconazole, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate 4g thereof, Xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand mill Effect under to make effective Ingredient percent be 51% biphenyl pyrrole bacterium amine epoxiconazole suspension concentrate.
Embodiment 13:32% biphenyl pyrrole bacterium amine epoxiconazole microemulsion (1:15)
Weigh 2g biphenyl pyrrole bacterium amine, 30g epoxiconazole, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphorus Acid esters 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.By above raw material The method preparing microemulsion routinely puts into mixing in mixing kettle, and making effective Ingredient percent is 32% biphenyl pyrrole bacterium Amine epoxiconazole microemulsion.
Embodiment 14:6% biphenyl pyrrole bacterium amine epoxiconazole aqueous emulsion (1:5)
Weigh 1g biphenyl pyrrole bacterium amine, 5g epoxiconazole, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkane Base phenol polyethenoxy ether 1g, 150# solvent naphtha 13g, adds water to 100g.Above raw material is prepared routinely the side of aqueous emulsion Method puts into the mixing of mixing kettle high speed, and making effective Ingredient percent is 6% biphenyl pyrrole bacterium amine epoxiconazole aqueous emulsion.
Embodiment 15:62% biphenyl pyrrole bacterium amine epoxiconazole microemulsion (1:30)
Weigh 2g biphenyl pyrrole bacterium amine, 60g epoxiconazole, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphorus Acid esters 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropanol 10g, add water to 100g.By above raw material The method preparing microemulsion routinely puts into mixing in mixing kettle, and making effective Ingredient percent is 62% biphenyl pyrrole bacterium Amine epoxiconazole microemulsion.
Embodiment 16:51% biphenyl pyrrole bacterium amine epoxiconazole suspension concentrate (1:50)
Weigh 1g biphenyl pyrrole bacterium amine, 50g epoxiconazole, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulfate 4g thereof, Xanthan gum 0.15g, ethylene glycol 5g, siloxanes 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, at sand mill Effect under to make effective Ingredient percent be 51% biphenyl pyrrole bacterium amine epoxiconazole suspension concentrate.
Embodiment 17:7% biphenyl pyrrole bacterium amine epoxiconazole water dispersion granule (1:2.5)
Weigh 2g biphenyl pyrrole bacterium amine, 5g epoxiconazole, wooden sodium sulfonate 8g, sodium lauryl sulphate 2g, ammonium sulfate 5g, Polyvinyl alcohol 5g, Borax 2g, white carbon 3g, kieselguhr complement to 100g, above raw material are pressed water dispersion granule side It is 7% biphenyl pyrrole bacterium amine epoxiconazole water dispersion granule that method makes effective ingredient mass percent.

Claims (10)

1. one kind contains biphenyl pyrrole bacterium amine and the bactericidal composition of epoxiconazole, it is characterised in that this bactericidal composition is with biphenyl pyrrole Bacterium amine and epoxiconazole are principle active component, and wherein biphenyl pyrrole bacterium amine is 1~70:1~50 with the mass ratio of epoxiconazole.
Bactericidal composition the most according to claim 1, it is characterised in that described biphenyl pyrrole bacterium amine and the matter of epoxiconazole Amount ratio is 1~50:1~50.
Bactericidal composition the most according to claim 2, it is characterised in that described biphenyl pyrrole bacterium amine and the matter of epoxiconazole Amount ratio is 1~30:2~50.
Bactericidal composition the most according to claim 3, it is characterised in that described biphenyl pyrrole bacterium amine and the matter of epoxiconazole Amount ratio is 1~30:2~10.
Bactericidal composition the most according to claim 1, it is characterised in that described biphenyl pyrrole bacterium amine and epoxiconazole two It is 2-80% that person accounts for the weight/mass percentage composition of compositions.
Bactericidal composition the most according to claim 5, it is characterised in that described biphenyl pyrrole bacterium amine and epoxiconazole two It is 5-70% that person accounts for the weight/mass percentage composition of compositions.
Bactericidal composition the most according to claim 1, it is characterised in that be main with biphenyl pyrrole bacterium amine and epoxiconazole Effective ingredient and insecticides adjuvant, excipient are configured on pesticide any one dosage form allowed.
Bactericidal composition the most according to claim 7, it is characterised in that described dosage form is cream, suspending agent, water Emulsion, wettable powder or water dispersion granule.
9. the application on preparation preventing and treating fungal diseases of plants medicine of the bactericidal composition described in claim 1.
Application the most according to claim 9, it is characterised in that described fungal diseases of plants be powdery mildew, rust, At least one in downy mildew, damping-off, eyeprint disease.
CN201610355222.4A 2016-05-25 2016-05-25 Sterilization composition containing Bixafen and epoxiconazole and application thereof Pending CN105941417A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106719690A (en) * 2016-12-08 2017-05-31 深圳诺普信农化股份有限公司 A kind of bactericidal composition of the bacterium of pyrrole containing biphenyl amine and its application

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009135834A2 (en) * 2008-05-08 2009-11-12 Basf Se Method for protecting soybeans from being infected by fungi
EP2220937A2 (en) * 2003-10-10 2010-08-25 Bayer CropScience AG Synergistic fungicidal combinations
US20100331181A1 (en) * 2008-02-28 2010-12-30 Basf Se Method for Protecting Cereals From Being Infected By Fungi
CN102246791A (en) * 2011-07-09 2011-11-23 海利尔药业集团股份有限公司 Compounded pesticide sterilizing composition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2220937A2 (en) * 2003-10-10 2010-08-25 Bayer CropScience AG Synergistic fungicidal combinations
US20100331181A1 (en) * 2008-02-28 2010-12-30 Basf Se Method for Protecting Cereals From Being Infected By Fungi
WO2009135834A2 (en) * 2008-05-08 2009-11-12 Basf Se Method for protecting soybeans from being infected by fungi
CN102246791A (en) * 2011-07-09 2011-11-23 海利尔药业集团股份有限公司 Compounded pesticide sterilizing composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106719690A (en) * 2016-12-08 2017-05-31 深圳诺普信农化股份有限公司 A kind of bactericidal composition of the bacterium of pyrrole containing biphenyl amine and its application

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Application publication date: 20160921