CN109395145B - Active polypeptide product for paper diapers and preparation method thereof - Google Patents
Active polypeptide product for paper diapers and preparation method thereof Download PDFInfo
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- CN109395145B CN109395145B CN201811478357.5A CN201811478357A CN109395145B CN 109395145 B CN109395145 B CN 109395145B CN 201811478357 A CN201811478357 A CN 201811478357A CN 109395145 B CN109395145 B CN 109395145B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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Abstract
The invention relates to an active polypeptide product for paper diapers, which comprises polypeptide, glycerol, chitosan, a chamomile extract, olive oil, butanediol and citric acid, wherein the polypeptide has the effects of repairing skin and improving skin resistance, the glycerol has a good moisturizing effect, the chamomile extract can protect the skin of infants and relieve skin allergy, the citric acid can prevent polypeptide oxidation and improve the using effect of the polypeptide, the whole product is purely natural and does not contain any chemical additive, the active polypeptide product can effectively protect skin and prevent allergy when being used on the paper diapers, the skin resistance is improved, the skin dependence is avoided, and the active polypeptide product has high practical value.
Description
Technical Field
The invention relates to the technical field of baby products, in particular to an active polypeptide product for paper diapers and a preparation method thereof.
Background
The paper diaper is one of the most common daily necessities for babies, the consumption amount reaches billions of sheets every year, the advantages of using the paper diaper are great, the babies are prevented from urinating the trousers, the burden of caregivers is relieved, and the toilet training in the future is facilitated. The skin of an infant is tender and frequent in urination and defecation, and the buttocks of some infants are easy to have skin allergy symptoms when the infants use the paper diaper, namely the red buttocks, so that the problem is solved, some paper diapers are coated with skin care components on the surfaces, and a chamomile extract is added in the paper diaper, but the infants are easy to have a dependence effect after long-time use, namely the self immune repair capability of the infants is reduced.
The polypeptide is an intermediate product of protein hydrolysis, has great influence on the growth, development, immunoregulation and metabolism of a human body, has good effects on antibiosis, skin protection and repair, and has no side effect.
Disclosure of Invention
The invention aims to solve the technical problems and provides an active polypeptide product for paper diapers and a preparation method thereof.
An active polypeptide product for paper diapers comprises the following components in parts by weight: 10-20 parts of polypeptide, 2-3 parts of glycerol, 5-10 parts of chitosan, 5-10 parts of chamomile extract, 1-3 parts of olive oil, 3-5 parts of butanediol and 0.5-1 part of citric acid.
In one embodiment, the composition comprises the following components in parts by weight: 15 parts of polypeptide, 2 parts of glycerol, 5 parts of chitosan, 10 parts of chamomile extract, 2 parts of olive oil, 4 parts of butanediol and 0.8 part of citric acid.
In one embodiment, the polypeptide is a soy extract plant peptide.
A production method of an active polypeptide product for paper diapers comprises the following steps:
1) cleaning and sterilizing soybeans, adding purified water according to the proportion of 1:1.2-1.5, and grinding to obtain a soybean suspension;
2) adding protease with the mass number of 0.2-0.5% of that of the soybean into the suspension for enzymolysis for 5-8 hours to obtain an enzymolysis liquid;
3) adding 0.1-0.3% of active carbon in mass fraction into the enzymolysis liquid, standing for 0.5-1 hr, separating with diatomite to obtain separation liquid, and freeze-drying the separation liquid to obtain polypeptide for use;
4) leaching chamomile by using ethanol as a solvent to obtain a chamomile extract for later use;
5) adding purified water with the mass ratio of 10-15 into the polypeptide in the step 3), adding chamomile extract, glycerol, chitosan, olive oil, butanediol and citric acid, stirring and mixing uniformly to obtain the polypeptide skin care lotion, and freeze-drying to obtain an active polypeptide product.
In one embodiment, the enzymolysis temperature in the step 2) is 55-60 ℃.
In one embodiment, the polypeptide with molecular weight of 2000-5000Da is obtained from the separation solution in step 3) by a permeation membrane method.
In one embodiment, the leaching manner in the step 4) is an ultrasonic extraction method.
To sum up, an active polypeptide product for panty-shape diapers, including polypeptide, glycerine, chitosan, chamomile extract, olive oil, butanediol, citric acid, the polypeptide has the effect of repairing skin and improving skin resistance, glycerine has good moisturizing effect, the chamomile extract can protect infant's skin, alleviate skin allergy, citric acid can prevent polypeptide oxidation, improve polypeptide result of use, whole product pure natural, do not have any chemical additive, can effectively protect skin and prevent allergy for on the panty-shape diapers, improve skin self resistance, can not let skin produce the dependence, higher practical value has.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clear, the present invention is further described in detail below with reference to examples. It should be understood that the specific embodiments described herein are only for better understanding of the technical solutions of the present invention, and are not intended to limit the present invention.
An active polypeptide product for paper diapers comprises the following components in parts by weight: 10-20 parts of polypeptide, 2-3 parts of glycerol, 5-10 parts of chitosan, 5-10 parts of chamomile extract, 1-3 parts of olive oil, 3-5 parts of butanediol and 0.5-1 part of citric acid.
In one embodiment, the composition comprises the following components in parts by weight: 15 parts of polypeptide, 2 parts of glycerol, 5 parts of chitosan, 10 parts of chamomile extract, 2 parts of olive oil, 4 parts of butanediol and 0.8 part of citric acid.
In one embodiment, the polypeptide is a soy extract plant peptide.
A production method of an active polypeptide product for paper diapers comprises the following steps:
1) cleaning and sterilizing soybeans, adding purified water according to the proportion of 1:1.2-1.5, and grinding to obtain a soybean suspension;
2) adding protease with the mass number of 0.2-0.5% of that of the soybean into the suspension, and performing enzymolysis at 55-60 deg.C for 5-8 hr to obtain enzymolysis solution;
3) adding 0.1-0.3% of active carbon in mass fraction into the enzymolysis liquid, standing for 0.5-1 h, separating by using diatomite to obtain a separation liquid, obtaining the polypeptide with the molecular weight of 2000-plus 5000Da by a permeation membrane method, and freeze-drying the permeated separation liquid to obtain the polypeptide for later use;
4) extracting flos Matricariae Chamomillae with ethanol as solvent by ultrasonic extraction method to obtain flos Matricariae Chamomillae extract;
5) adding purified water with the mass ratio of 10-15 into the polypeptide in the step 3), adding chamomile extract, glycerol, chitosan, olive oil, butanediol and citric acid, stirring and mixing uniformly to obtain the polypeptide skin care lotion, and freeze-drying to obtain an active polypeptide product.
The polypeptide has an excellent repairing effect, improves the skin resistance, and simultaneously, the prepared materials have a good skin care effect, cannot cause irritation to the hip skin of the infant, are used for the paper diaper, improve the skin resistance and repairing capability of the infant, and fundamentally improve the problem of skin allergy, namely what is commonly referred to as 'red buttock'. The polypeptide is prepared from soybean, the prepared plant polypeptide is easier to be absorbed by human body, the effect is optimal, and finally the polypeptide with the molecular weight of 2000-5000Da (Dalton) with the optimal absorption effect and the highest yield is selected in the preparation process. The chamomile extract has a good protection effect on the skin, is easy to cause the skin to generate a side effect of dependence after being used alone for a long time, and can improve the side effect because the polypeptide has a small molecular weight, is easy to be absorbed by cells and can improve the self resistance of the skin when being used together with the polypeptide.
The final product can be directly clamped in the paper diaper in application and use, the more effective use method is that the polypeptide skincare solution is sprayed on the dust-free paper or non-woven fabric on the top of the paper diaper, the paper diaper is packaged after being dried in a sterile environment, the effective cost of the polypeptide skincare solution is in direct contact with the skin of an infant, and the production is simple and the production is easy to streamline.
Example 1
A production method of an active polypeptide product for paper diapers comprises the following steps:
1) cleaning and sterilizing soybeans, adding purified water according to the proportion of 1:1.2, and grinding to obtain a soybean suspension;
2) adding protease with the mass number of 0.2% of that of the soybeans into the suspension, and carrying out enzymolysis at the temperature of 60 ℃ for 5 hours to obtain an enzymolysis solution;
3) adding 0.1% of active carbon by mass into the enzymolysis liquid, standing for 0.5 h, separating with diatomite to obtain a separation liquid, obtaining polypeptide with the molecular weight of 5000Da by a permeation membrane method, and freeze-drying the permeated separation liquid to obtain the polypeptide for later use;
4) extracting flos Matricariae Chamomillae with ethanol as solvent by ultrasonic extraction method to obtain flos Matricariae Chamomillae extract;
5) adding 20 parts of polypeptide in the step 3) into 15 parts of purified water by mass ratio, adding 5 parts of chamomile extract, 3 parts of glycerol, 10 parts of chitosan, 5 parts of olive fruit oil, 3 parts of butanediol and 1 part of citric acid, stirring and uniformly mixing the polypeptide skin care solution, and freeze-drying to obtain the active polypeptide product.
Example 2
A production method of an active polypeptide product for paper diapers comprises the following steps:
1) cleaning and sterilizing soybeans, adding purified water according to the proportion of 1:1.5, and grinding to obtain a soybean suspension;
2) adding protease with the mass number of 0.5% of that of the soybean into the suspension, and carrying out enzymolysis for 8 hours at the temperature of 55 ℃ to obtain an enzymolysis liquid;
3) adding 0.3% of active carbon by mass into the enzymolysis liquid, standing for 1 hour, separating with diatomite to obtain a separation liquid, obtaining polypeptide with molecular weight of 3000Da by a permeation membrane method, and freeze-drying the separation liquid after permeation to obtain the polypeptide for later use;
4) extracting flos Matricariae Chamomillae with ethanol as solvent by ultrasonic extraction method to obtain flos Matricariae Chamomillae extract;
5) 10 parts of polypeptide in the step 3) is added with 10 parts of purified water by mass ratio, 10 parts of chamomile extract, 2 parts of glycerol, 10 parts of chitosan, 10 parts of olive fruit oil, 5 parts of butanediol and 0.5 part of citric acid are added, the polypeptide skin care lotion which is uniformly mixed is stirred, and the active polypeptide product is obtained by freeze drying.
Example 3
A production method of an active polypeptide product for paper diapers comprises the following steps:
1) cleaning and sterilizing soybeans, adding purified water according to the proportion of 1:1.3, and grinding to obtain a soybean suspension;
2) adding protease with the mass number of 0.4% of that of the soybeans into the suspension, and carrying out enzymolysis for 6 hours at the temperature of 58 ℃ to obtain an enzymolysis liquid;
3) adding 0.2% of active carbon by mass into the enzymolysis liquid, standing for 0.8 h, separating with diatomite to obtain a separation liquid, obtaining polypeptide with the molecular weight of 4000Da by a permeation membrane method, and freeze-drying the permeated separation liquid to obtain the polypeptide for later use;
4) extracting flos Matricariae Chamomillae with ethanol as solvent by ultrasonic extraction method to obtain flos Matricariae Chamomillae extract;
5) adding purified water with the mass ratio of 12 into 15 parts of polypeptide in the step 3), adding 8 parts of chamomile extract, 2 parts of glycerol, 8 parts of chitosan, 8 parts of olive fruit oil, 4 parts of butanediol and 0.8 part of citric acid, stirring and mixing uniformly to obtain the polypeptide skin care solution, and freeze-drying to obtain the active polypeptide product.
The above-described embodiments are only preferred embodiments of the present invention, and it should be noted that, for those skilled in the art, modifications and variations can be made without departing from the principle of the present invention, and such modifications and variations should also be construed as not departing from the scope of the present invention.
Claims (6)
1. An active polypeptide product for paper diapers is characterized by comprising the following components in parts by weight: 10-20 parts of polypeptide, 2-3 parts of glycerol, 5-10 parts of chitosan, 5-10 parts of chamomile extract, 1-3 parts of olive oil, 3-5 parts of butanediol and 0.5-1 part of citric acid, wherein the polypeptide is soybean extracted plant peptide, and the molecular weight of the polypeptide is 2000-5000 Da.
2. The active polypeptide product for the paper diapers as claimed in claim 1, which is characterized by comprising the following components in parts by weight: 15 parts of polypeptide, 2 parts of glycerol, 5 parts of chitosan, 10 parts of chamomile extract, 2 parts of olive oil, 4 parts of butanediol and 0.8 part of citric acid.
3. A method for producing an active polypeptide product for diapers according to any of claims 1-2, comprising the steps of:
1) cleaning and sterilizing soybeans, adding purified water according to the proportion of 1:1.2-1.5, and grinding to obtain a soybean suspension;
2) adding protease with the mass number of 0.2-0.5% of that of the soybean into the suspension for enzymolysis for 5-8 hours to obtain an enzymolysis liquid;
3) adding 0.1-0.3% of active carbon in mass fraction into the enzymolysis liquid, standing for 0.5-1 hr, separating with diatomite to obtain separation liquid, and freeze-drying the separation liquid to obtain polypeptide for use;
4) leaching chamomile by using ethanol as a solvent to obtain a chamomile extract for later use;
5) adding purified water with the mass ratio of 10-15 into the polypeptide in the step 3), adding chamomile extract, glycerol, chitosan, olive oil, butanediol and citric acid, stirring and mixing uniformly to obtain the polypeptide skin care lotion, and freeze-drying to obtain an active polypeptide product.
4. The method for producing the active polypeptide product for the paper diaper according to claim 3, wherein the method comprises the following steps: the enzymolysis temperature in the step 2) is 55-60 ℃.
5. The method for producing the active polypeptide product for the diaper according to claim 4, wherein the method comprises the following steps: the polypeptide with the molecular weight of 2000-5000Da is obtained in the separation liquid in the step 3) by a permeation membrane method.
6. The method for producing the active polypeptide product for the diaper according to claim 4, wherein the method comprises the following steps: the leaching mode in the step 4) is an ultrasonic extraction method.
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| CN201811478357.5A CN109395145B (en) | 2018-12-05 | 2018-12-05 | Active polypeptide product for paper diapers and preparation method thereof |
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| CN201811478357.5A CN109395145B (en) | 2018-12-05 | 2018-12-05 | Active polypeptide product for paper diapers and preparation method thereof |
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| CN109395145B true CN109395145B (en) | 2021-05-18 |
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| CN101966137B (en) * | 2010-09-30 | 2014-06-18 | 天津市中科健新材料技术有限公司 | Multi-efficacy skin-care preparation composition as well as preparation method and application thereof |
| CN102228802A (en) * | 2011-06-27 | 2011-11-02 | 张会艳 | Food-grade antibacterial filter membrane and preparation method thereof |
| CN102987275B (en) * | 2012-12-28 | 2018-06-01 | 长春大学 | A kind of preparation method of the soy oligosaccharides glycopeptide of high biological value |
| CN105796249A (en) * | 2016-05-19 | 2016-07-27 | 俞祖勋 | Manufacturing method of paper diaper using antibacterial polypeptide and antibacterial paper diaper thereof |
| CN108553333A (en) * | 2018-07-12 | 2018-09-21 | 哈尔滨伟平科技开发有限公司 | A kind of production method of anti-bacterial hand lotion |
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